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Abbreviation : AA
Long Form : arachidonic acid
No. Year Title Co-occurring Abbreviation
1975 Cardiovascular and platelet responses in the dog to the monoenoic prostaglandin precursor dihomo-gamma-linolenic acid. DGLA, SAP
1975 Effects of ganglionic and beta-adrenergic blockade on cardiovascular responses to the bisenoic prostaglandins and their precursor arachidonic acid. ---
1975 Modifications of canine vascular smooth muscle responses to dihydroergotamine by endogenous prostaglandin synthesis. DHE, NA
1975 Potentiation of bradykinin-induced vascular permeability increase by prostaglandin E2 and arachidonic acid in rabbit skin. BK, DPP, Hist, PG
1975 The inhibiting effect of indomethacin on the disruption of the blood-aqueous barrier in the rabbit eye. AF, AFR, alpha-MSH, PGE2
1976 Dog platelets fail to aggregate when they form aggregating substances upon stimulation with arachidonic acid. ---
1976 The effect of imidazole on the disruption of the blood-aqueous barrier in the rabbit eye. AF, alpha-MSH
1976 Vascular responses to arachidonic acid in the perfused canine lung. NE, PGF2a
1977 Beneficial effect of arachidonic acid during hemorrhagic shock in the dog. MABP, MDF, PG, RAF, SMAF
10  1977 Effect of the prostaglandin precursor, arachidonic acid, on histamine stimulated gastric secretion in the conscious dog, and observations on the effect of inhibiting endogenous prostaglandin synthesis. ETYN, PGE2
11  1977 Elevation of prostaglandin and cyclic AMP levels by arachidonic acid in primary epithelial cell cultures of C3H mouse mammary tumors. ---
12  1977 Human synovial fibroblasts: the relationships between cyclic AMP, bradykinin, and prostaglandins. BK, FCS, IM, PGE1
13  1977 Prostaglandins and the control of blood flow in the canine myocardium. EMFP, IND, Mf, PG
14  1977 Vascular responses to the monoenoic prostaglandin precursor dihomo-gamma-linolenic acid in the perfused canine lung. DGLA, PG
15  1977 Vasoconstrictor response to arachidonic acid in the isolated hind limb of the dog. ---
16  1978 Antagonism of the pulmonary vasoconstrictor response to prostaglandin F2alpha by N-dimethylamino substitution of prostaglandin F2alpha. PG
17  1978 Antihypertensive effect of volume depletion: interrelation with renal prostaglandins. iPGE2
18  1978 Arachidonic acid-induced platelet aggregation and thromboxane A2 generation in patients with coronary heart disease. TXA2
19  1978 Cardiovascular responses to PGI2 (prostacyclin) in the dog. MCF, PAP, PG
20  1978 E-UFA test in multiple sclerosis. LA
21  1978 Effect of lung transit on systemic depressor responses to arachidonic acid and prostacyclin in dogs. i.v
22  1978 Effects of arachidonic acid and prostaglandins on lung function in the intact dog. Cdyn, PG, Ppa
23  1978 Generation and release of eosinophil chemotactic factor from human polymorphonuclear neutrophils by arachidonic acid. ECF
24  1978 Hyperthermic effects of arachidonic acid, prostaglandin E2 and F2alpha in rats. PG, TXA2
25  1978 Prostaglandins: renal vascular responses to bradykinin, histamine, and nitroglycerine. IND, MEC, PG
26  1978 Role of platelets in aspirin-sensitive bronchoconstriction in the guinea-pig; interactions with salicylic acid. ADP, ATP, PRP
27  1978 The effects of arachidonic acid on erythropoietin production in exhypoxic polycythemic mice and the isolated perfused canine kidney. Ep
28  1978 The role of iron in prostaglandin synthesis: ferrous iron mediated oxidation of arachidonic acid. TBA
29  1978 Thromboxane generation and platelet aggregation in survivals of myocardial infarction. TXA2
30  1978 Transformation of arachidonic acid and prostaglandin endoperoxides by the guinea pig heart. Formation of RCS and prostacyclin. 15-HPAA, BCA, CR, PLS, RBA, RC, RCS, RSS
31  1979 Anti-aggregatory effect of prostacyclin (PGI2) in vivo. ---
32  1979 Arachidonic acid causes lysis of human platelets in an artificial medium: protection by plasma. LT, WPS
33  1979 Atherosclerosis decreased prostacyclin formation in rabbit lungs and kidneys. ---
34  1979 Biotransformation and cardiovascular effects of arachidonic acid in the dog. TXA2
35  1979 Combined effect of prostaglandins and an aortic proteoglycan on platelet aggregation and plasma clotting. APG
36  1979 Differential effects of probenecid on the levels of endogenous PGF2 alpha and TXB2 in brain cortex. PMT
37  1979 Differential effects of prostacyclin and prostaglandin E1 on bronchoconstriction and thrombocytopenia during collagen and arachidonate infusions and anaphylactic shock in the guinea-pig. PGE1
38  1979 Effect of inhibitors of arachidonic acid metabolism on mitogenesis in human lymphocytes: possible role of thromboxanes and products of the lipoxygenase pathway. ---
39  1979 Eosinophil chemotactic factor. Release from human polymorphonuclear neutrophils by arachidonic acid. ECF
40  1979 Prostacyclin-dependent differences in TXA2 formation by platelets from normal and atherosclerotic rabbits. HETE, TXB2
41  1979 Prostaglandin and thromboxane production by human and guinea-pig macrophages and leucocytes. ---
42  1979 Prostaglandin biosynthesis in pulmonary macrophages. BCG, CB, PC, PG
43  1979 Prostaglandins as inhibitors of human platelet aggregation. PG
44  1979 Relation between ulcerogenic activity of various NSAID and their potency as inhibitors of prostaglandin synthesis in vivo. NSAID
45  1979 Slow reacting substance (SRS) from ionophore A23187-stimulated peritoneal mast cells of the normal rat. II. Evidence for a precursor role of arachidonic acid and further purification. ETYA, SRS
46  1979 The effects of albumin bound fatty acids on the platelet inhibitory function of human endothelial cells. DHLA, FA, PA
47  1979 The effects of glucocorticoids on the distribution and mobilisation of arachidonic acid in fat cell ghosts. ACTH, PGE2
48  1979 The metabolism of dihomo-gamma-linolenic acid in man. DHLA
49  1979 Thrombocytopathy in preleukaemia: association with a defect of thromboxane A2 activity. ADP, MDA, TXA2, TXB2
50  1980 A simple method for estimation of lipoxygenase and cyclo-oxygenase pathways in human platelets--the use of thiobarbituric acid reaction. MDA, PLO, TBA
51  1980 Aggregation and inhibition of rat platelets, and the formation of endoperoxide metabolites. ADP, PGs, PRP, TXA2
52  1980 Calcium ionophore A23187 induces release of chemokinetic and aggregating factors from polymorphonuclear leucocytes. PMNs
53  1980 Cardiac synthesis of prostaglandins from arachidonic acid in man. ---
54  1980 Differences in biological activation of arachidonic acid in perfused lungs from guinea pig, rat and man. ---
55  1980 Differential effects of local anesthetics and propranolol on arachidonic acid and adenosine 5'-diphosphate-induced aggregation in rabbit platelets. ADP, PRP
56  1980 Differential effects of prostaglandins and arachidonic acid on gastric circulation and oxygen consumption. PGE2
57  1980 Effect of prostaglandin on the composition of chinchilla middle ear effusion. LDH, ME, MEE, PGs, POM, SOM, TLC
58  1980 Effect of the 5-hydroperoxide of eicosatetraenoic acid and inhibitors of the lipoxygenase pathway on the formation of slow reacting substance by rat basophilic leukemia cells; direct evidence that slow reacting substance is a product of the lipoxygenase pathway. 5-HPETE, SRS
59  1980 Effects of prostaglandins on adrenal steroidogenesis in the rat. ACTH, AII, PGE2, PGF2 alpha
60  1980 Evidence for lipoxygenase pathway involvement in allergic tracheal contraction. ---
61  1980 Further observations with the erythrocyte-unsaturated fatty acid test. A contribution to the genetics of multiple sclerosis. MS
62  1980 Influence of thromboxane inhibition on the severity of myocardial ischemia in cats. CPK, MI, TX, TXB2
63  1980 Metabolism of arachidonic acid and its endoperoxide (PGH2) to myotropic products in guinea-pig and rabbit isolated lungs. ---
64  1980 Metabolism of [14C] arachidonic acid in the isolated rabbit spleen. PG
65  1980 PGE2, PGF2 alpha, and TXB2 biosynthesis by human rheumatoid synovia. OA, PG, RA, TXB2
66  1980 Prostacyclin and thromboxane A2 synthesis by rabbit pulmonary artery. i.p.a, PG, TX
67  1980 Prostaglandins and thromboxanes in amniotic fluid during rivanol-induced abortion and labour. 6-keto-PGF1 alpha, PGE2, PGF2 alpha, TXB2
68  1980 Prostaglandins evoke a whole variety of responses in the lung. PAP, PVR
69  1980 Prostaglandins, platelets, and atherosclerosis. ---
70  1980 Selective inhibitory effects of chlorpromazine and imipramine on platelet aggregation. ADP, CPZ, IMP
71  1980 Separation of prostaglandins, thromboxane, hydroxy fatty acids and arachidonic acid by high pressure liquid chromatography. PGs, TXB2
72  1980 Synthesis of thromboxane B2 and 6-keto-prostaglandin F1 alpha by bovine gastric mucosal and muscle microsomes. 6-keto-PGF1 alpha
73  1980 The effect of arachidonic- and eicosapentaenoic acid on the synthesis of prostacyclin-like material in human umbilical vasculature. EPA
74  1980 The effect of conditions influencing endogenous prostaglandins on the activity of delta'-tetrahydrocannabinol in mice. ---
75  1980 The role of arachidonate lipoxygenase in the release of SRS-A from guinea-pig chopped lung. ETA, NDGA
76  1980 Thromboxane generation in patients with essential hypertension or cerebrovascular disease and effect of oral aspirin. CVD, PGH2, TXB2
77  1980 [Effect of short-term administration of sunflower oil on the blood serum level of linoleic and arachidonic acids and lipids in multiple sclerosis]. LA
78  1980 [Prostaglandin biosynthesis in psoriatic epidermis (author's transl)]. PGE2
79  1981 9 alpha-homo-9,11-epoxy-5,13-prostadienoic acid analogues: specific stable agonist (SQ 26, 538) and antagonist (SQ 26, 536) of the human platelet thromboxane receptor. PG, TX
80  1981 A method for the bioassay of intestinal secretory activity in the conscious rat: studies with arachidonic acid and prostaglandin E2. ---
81  1981 Anti-inflammatory effects of betamethasone phosphate, dexamethasone phosphate and indomethacin on rabbit ocular inflammation induced by bovine serum albumin. PMNs
82  1981 Cerebral prostaglandin biosynthesis and angiotensin-induced drinking in rats. PGE2
83  1981 Conversion of exogenous arachidonic acid to prostaglandins in the pulmonary circulation in vivo. A human and animal study. PGs
84  1981 Differential effects of dietary fatty acids on the accumulation of arachidonic acid and its metabolic conversion through the cyclooxygenase and lipoxygenase in platelets and vascular tissue. CO, LA, PI, TXB2
85  1981 Effect of arachidonic acid and indomethacin on renal function of dogs with pericardial tamponade. PG
86  1981 Effect of arachidonic acid on normal and dystrophic retinal pigment epithelium in tissue culture. RPE
87  1981 Effect of arachidonic acid on the hexose monophosphate shunt and related coenzymes in human blood platelets. HMPS
88  1981 Effect of verapamil on the pulmonary vasoconstrictor action of prostaglandin F2 alpha and a synthetic PGH2 analogue. PGF2 alpha
89  1981 Effects of arachidonic acid hydroperoxides on vascular and non-vascular smooth muscle. GPI, RAS
90  1981 Effects of arachidonic acid, monohydroxyeicosatetraenoic acid and prostaglandins on the release of mucous glycoproteins from human airways in vitro. NSAID, PG
91  1981 Effects of extracellular Ca2+ and the intracellular Ca2+ antagonist 8-(n,n-diethylamino)octyl-3,4,5-trimethoxybenzoate on rabbit platelet conversion of arachidonic acid into thromboxane. TMB-8, TXB2
92  1981 Effects of methylprednisolone and hydrocortisone on aggregation of rabbit platelets induced by arachidonic acid and other aggregating substances. ADP, PG, PRP
93  1981 Enhanced thromboxane A2 biosynthesis in the kidney of spontaneously hypertensive rats during development of hypertension. PG, RHR, SHR, WKY
94  1981 Evidence for the generation of hydroxyl radical during arachidonic acid metabolism by human platelets. OH, SOD
95  1981 Human umbilical blood vessel converts all cis-5, 8, 11, 14, 17 eicosapentaenoic acid to prostaglandin I3. EPA
96  1981 In vitro effects of synthetic antioxidants and vitamin E on arachidonic acid metabolism and thromboxane formation in human platelets and on platelet aggregation. BHA, BHT, TXB2
97  1981 Inhibition of platelet aggregation by 6-keto-PGE1; lack of an effect on cyclic GMP levels. ADP, PRP
98  1981 Lipid metabolism during mediator release from mast cells: studies of the role of arachidonic acid metabolism in the control of phospholipid metabolism. PA, PC, PI, PL
99  1981 Lipoxygenase pathway and hydroperoxy acids: possible relevance to aspirin-induced asthma and hyperirritability of airways in asthmatics. ---
100  1981 Mediators of immune-complex-induced aggregation of polymorphonuclear neutrophils. II. Platelet-activating factor as the effector substance of immune-induced aggregation. CP, IC, PAF, PMN
101  1981 Metabolism of exogenous arachidonic acid by murine macrophage-like tumor cell lines. HHT, TXB2
102  1981 Metabolites of arachidonic acid formed by human gastrointestinal tissues and their actions on the muscle layers. 12-HETE, PGD2, TXB2
103  1981 Molecular mechanisms of inflammation. ---
104  1981 Neonatal platelet function: a membrane-related phenomenon? HHT
105  1981 Plasma and platelet lipid composition and platelet aggregation by arachidonic acid in women on the pill. FFA, OC, TAC
106  1981 Platelet aggregation induced by arachidonic acid and thromboxane generation in patients with hypertension or cerebrovascular disease. CVD, PGH2, TXB2
107  1981 Platelet malondialdehyde production and aggregation responses induced by arachidonate, prostaglandin-G2, collagen, and epinephrine in 12 patients with storage pool deficiency. ADP, MDA, SPD
108  1981 Premature labor. I. Prostaglandin precursors in human placental membranes. PC, PE, PI, PS
109  1981 Prostacyclin (PGI2) and U-46619 stimulate coronary arteries from diabetic dogs and their action is influenced by inhibitors of prostaglandin biosynthesis. TX
110  1981 Prostacyclin (PGI2) mediates hypoxic relaxation of bovine coronary arterial strips. BCA, EYA, PGs
111  1981 Prostacyclin production in rabbit arteries in situ: inhibition by arachidonic acid-induced endothelial cell damage or by low-dose aspirin. 6-k-PGF1 alpha, ASA, TXB2
112  1981 Prostacyclin-thromboxane interactions in the platelet-perfused in vitro heart. ---
113  1981 Prostaglandin levels in isolated brain microvessels and in normal and norepinephrine-stimulated cat brain homogenates. 6KF1 alpha, GC/MS, NE
114  1981 Prostaglandins and renin release in vitro. dmPGE2, EPA, ETA, PGF2 alpha
115  1981 Prostanoids and hemostasis in chickens: anti-aggregating activity of prostaglandins E1 and E2, but not of prostacyclin and prostaglandin D2. ADP, PG
116  1981 Relationship of inhibition of prostaglandin synthesis in platelets to anti-aggregatory and anti-inflammatory activity of some benzoic acid derivatives. 2-PBA, 3-MP, 3-PBA, ABA, PG
117  1981 Release of platelet-activating factor (PAF-acether) and arachidonic acid metabolites from alveolar macrophages. AM
118  1981 Sites of prostaglandin synthesis in the bovine heart and isolated bovine coronary microvessels. ---
119  1981 Steroid 17 alpha-hydroxylase activity of ovarian granulosa cells from hypophysectomized immature rats treated with pregnant mare's serum gonadotropin (PMS). PG, PLA2, PMS
120  1981 Studies on topological distribution of arachidonic acid replacement in platelet phospholipids and on enzymes involved in the phospholipid effect accompanying platelet activation. PC, PI
121  1981 The actions of prostaglandins and cyclo-oxygenase inhibition on the resistance vessels supplying the human fetal placenta. AII, BK, Mf, PG's
122  1981 The effect of cigarette smoke on the metabolism of arachidonic acid in isolated hamster lungs. ---
123  1981 The effect of cod liver oil and corn oil on platelets and vessel wall in man. CLO, CO, E and F series, EPA
124  1981 The effects of albumin-bound unsaturated fatty acids on platelets. DHLA, FA, PF3, PRP
125  1981 The effects of prostaglandins and arachidonic acid on the electroretinogram: evidence for functional cyclooxygenase activity in the retina. ERG, PGs
126  1981 Trapped blood elements within the decidua of the rat pregnant uterus generate a lipoxygenase product(s) which inhibits myometrial prostacyclin synthesis. ETA
127  1981 [Interaction of phenothiazinic anti-inflammatory agent, protizinic acid, with the biopolymers: Inhibitory effects on functions of platelets (author's transl)]. IM, MZA, PZA
128  1982 A comparative study on the effect of cis (oleic, linoleic) and trans (elaidic, linoelaidic) fatty acids on the in vitro prostaglandin biosynthesis in human blood platelets from (1-14C) arachidonic acid. ---
129  1982 Alpha-adrenergic stimulation of prostaglandin release from rabbit iris-ciliary body in vitro. ICB, PGs
130  1982 Alteration in immune complex glomerulonephritis by arachidonic acid. ---
131  1982 Altered prostaglandin synthesis in isolated lungs of rats with streptozotocin-induced diabetes. ---
132  1982 Aspirin inhibits arachidonic acid metabolism via lipoxygenase and cyclo-oxygenase in hamster isolated lungs. ---
133  1982 Characteristics of the formation of the platelet lipoxygenase product from endogenous arachidonic acid. 12-HETE, EFAD, PRP
134  1982 Coronary flow reactions to arachidonic acid are inhibited by docosahexaenoic acid. DHx
135  1982 Coronary vasoconstrictor and vasodilator actions of arachidonic acid in the isolated perfused heart of the rat. NSAA, PGE2
136  1982 Differences in the central actions of arachidonic acid and prostaglandin F2 alpha between spontaneously hypertensive and normotensive rats. i.c.v, NR, PGF2 alpha, SHR
137  1982 Effect of corticosterone, hydrocortisone and prostaglandin fatty acid precursors on the spontaneous motility of the uterus isolated from ovariectomized rats. LA, PG
138  1982 Effect of linoleic acid-rich diet on blood pressure, lipids, catecholamines, and dopamine -beta-hydroxylase in spontaneously hypertensive rats. LA, LAR, SHR
139  1982 Effects of angiotensin II on phosphatidylinositol and polyphosphoinositide turnover in rat kidney. Mechanism of prostaglandin release. PG
140  1982 Effects of arachidonic acid and bradykinin on the coronary flow, release of PGI2 and cardiac functions in the perfused guinea-pig heart. BK
141  1982 Effects of etamsylate on platelet functions and arachidonic acid metabolism. ---
142  1982 Enhanced affinity for arachidonic acid in platelet-rich plasma from rats with Adriamycin-induced nephrotic syndrome. MDA, PRP
143  1982 Evidence for two distinct forms of fatty acid cyclooxygenase in brain. PGE2, PGF2 alpha
144  1982 Experimental and clinical results in shock lung treatment with vitamin E. ARDS, SOD
145  1982 Generation of leukotriene B4, its all trans isomers and 5-hydroxyeicosatetraenoic acid by rat basophilic leukaemia cells. 5-HETE, GPISM, GPPs, h.p.l.c, LT, PMNs
146  1982 Hepatic arachidonic acid metabolism following in vitro perfusion and endotoxin administration. ---
147  1982 Identification of prostaglandins and other arachidonic acid metabolites in experimental otitis media. 15-HETE, HHT, MEM, PGs
148  1982 In vitro and in vivo effects of vitamin E on arachidonic acid metabolism in rat platelets. PRP
149  1982 Increased platelet aggregability is associated with increased prostacyclin production by vessel walls in hypercholesterolemic rabbits. HC, PRP
150  1982 Influence of ascorbic acid on platelet aggregation in vitro and in vivo. MDA, PA, PRP
151  1982 Inhibition by sulphinpyrazone of the platelet-dependent bronchoconstriction due to platelet-activating factor (PAF-acether) in the guinea pig. ---
152  1982 Potentiation by dazoxiben, a thromboxane synthetase inhibitor, of platelet aggregation inhibitory activity of a thromboxane receptor antagonist and of prostacyclin. PG, TX
153  1982 Prostaglandin endoperoxides, thromboxane A2 and adenosine diphosphate in collagen-induced aggregation of rabbit platelets. ADP
154  1982 Prostaglandin synthesis in aorta and platelets of fawn-hooded rats with platelet storage pool disease and its response to cholesterol feeding. FH, PGF1 alpha, SD, TXB2
155  1982 Release of different prostaglandins from vascular tissue by different stimulators. PLA2
156  1982 Selective destruction of the outer leaflet of the capillary endothelial membrane after intracerebral injection of arachidonic acid in the rat. ---
157  1982 SIN-1, the main metabolite of molsidomine, inhibits prostaglandin endoperoxide analogue- and arachidonic acid-induced platelet aggregation as well as platelet thromboxane A2 formation. PRP, TXA2
158  1982 Stimulation of arachidonic acid metabolism and generation of thromboxane A2 by leukotrienes B4, C4 and D4 in guinea-pig lung in vitro. BK, GPPs, LTC4, SRS-A, TXA2
159  1982 Subnormal platelet response to thromboxane A2 in a patient with chronic myeloid leukaemia. TXA2
160  1982 Suppression of murine T-cell mitogenesis by metabolic products of arachidonic acid. ---
161  1982 The effect of aspirin pretreatment on the fate of arachidonic acid in hamster isolated lungs. ---
162  1982 The effect of ticlopidine on the aggregation of rat blood platelets and on the formation of metabolites from arachidonic acid and 8,11,14-eicosatrienoic acid in rat platelets during aggregation, and in the rat kidney. HETE, HHD, HHT, TXB2
163  1982 The lack of correlation between inhibition of aggregation and cAMP levels with canine platelets. EPI, PDIs
164  1982 The metabolism of arachidonic acid to an antiaggregatory compound in isolated lungs of fetal and neonatal rabbits. PRP
165  1982 Thromboxane A2/prostaglandin H2 directly stimulates platelet shape change independent of secreted ADP. 13-APA, PG, TX
166  1982 Uptake of arachidonic acid into membrane phospholipids: effect on chloride transport across cornea. ---
167  1983 2-(6-carboxyhexyl)cyclopentanone hexylhydrazone. A potent and time-dependent inhibitor of platelet aggregation. ---
168  1983 A rapid and simple assay for the study of thromboxane B2 synthesis by intact human platelets. TLC, TXB2
169  1983 A role for cyclooxygenase products in the formation of phosphatidic acid in stimulated human platelets. Differential mechanisms of action of thrombin and collagen. PA
170  1983 A role for the lipoxygenase pathway of arachidonic acid metabolism in glucose- and glucagon-induced insulin secretion. ---
171  1983 Antianginal drug trapidil (Rocornal) inhibits spreading of platelets and formation of surface-bound thrombi-like aggregates. CSC, PG, TXA2
172  1983 Antiplatelet effects of isosorbide dinitrate in man. CPA, ISDN, PRP, TX
173  1983 Arachidonate induced aggregation of rat platelets may not require prostaglandin endoperoxides or thromboxane A2. ADP, PGH2, PRP, TXA2, TXB2
174  1983 Arachidonate metabolism in bovine gallbladder muscle. ---
175  1983 Arachidonic acid and stable analogue of prostaglandin endoperoxides (U46619) induce platelet spreading and thrombi-like aggregate formation on a collagen substrate. Effect of fluid dynamics. CSC, SEM
176  1983 Arachidonic acid induced platelet aggregation and thromboxane formation is inhibited by OKY-1581. TXB2
177  1983 Arachidonic acid protection of gastric mucosa against alcohol injury: sequential analysis of morphologic and functional changes. EtOH
178  1983 Arachidonic acid stimulates the formation of 1,2-diacylglycerol and phosphatidic acid in human platelets. Degree of phospholipase C activation correlates with protein phosphorylation, platelet shape change, serotonin release, and aggregation. PA
179  1983 Are blastocyst prostaglandins produced endogenously? PGs, TLC
180  1983 Biosynthesis of cyclooxygenase and lipoxygenase metabolites of arachidonic acid by rabbit renal microsomes. 12-HETE, 5-HETE, LT, RP-HPLC, UV
181  1983 Bradykinin-stimulated electrolyte secretion in rabbit and guinea pig intestine. Involvement of arachidonic acid metabolites. BK, ETYA, Isc, PGE2, SRS-A, VIP
182  1983 Changes of polyunsaturated fatty acids in serum lipids of spontaneously hypertensive rats during the onset of high blood pressure. EPA, LA, PUFA, SHR, WR
183  1983 Conversion of arachidonic acid to cyclooxygenase and lipoxygenase products, and incorporation into phospholipids in the mouse neuroblastoma clone, Neuro-2A. ETYA, HETE, PGs
184  1983 Cyclooxygenase products and cyclic nucleotide levels with infusion of arachidonic acid, PGI2, PGE2, PGF2, and 6-keto-PGF1 in an isolated dog lung. PGs
185  1983 Different effect of diatrizoate and iopamidol on prostaglandin synthesis in perfused hamster lungs. RCM
186  1983 Effect of arachidonic acid on the basal release of prostaglandins E2 and I2 by rat arteries during the development of hypertension. PG, SH, WKY
187  1983 Effect of eicosatetraenyl (3-aminopropyl) phosphonate (URI-73A) on platelet aggregation and arachidonic acid metabolism. ---
188  1983 Effect of oral administration of highly purified eicosapentaenoic acid on platelet function, blood viscosity and red cell deformability in healthy human subjects. DHA, EPA
189  1983 Effects of bradykinin and bovine serum albumin on arachidonic acid and prostaglandin release from perfused rat heart. BK, BSA, PG
190  1983 Effects of eicosapentaenoic acid on arachidonic acid metabolism in cultured vascular cells and platelets: species difference. EPA, PGs, TXA2
191  1983 Effects of thromboxane synthetase inhibitors on aggregation of rabbit platelets. PGs, TX
192  1983 Endothelium-dependent relaxation of rabbit aorta. I. Relaxation stimulated by arachidonic acid. ---
193  1983 Endothelium-dependent relaxation of rabbit aorta. II. Inhibition of relaxation stimulated by methacholine and A23187 with antagonists of arachidonic acid metabolism. QUIN
194  1983 Enhancement of neutrophil- and eosinophil-mediated complement-dependent killing of schistosomula of Schistosoma mansoni in vitro by leukotriene B4. ---
195  1983 Failure of acute hypoxia to alter pulmonary prostaglandin metabolism in dogs. PG
196  1983 Free-radical inhibition of ATPase in hamster cheek pouch homogenates. HX/XO
197  1983 Human platelet secreted proteins and prostacyclin production by bovine aortic endothelial cells. LA-PF4, PBP, PDGF, PF4
198  1983 Hydroperoxide-dependent activation of p-phenetidine catalyzed by prostaglandin synthase and other peroxidases. HRP, PGS, RSV
199  1983 Hyperreactivity of coronary vasculature in platelet-perfused hearts from diabetic rats. PGF2 alpha, TXB2
200  1983 Impact of insulin or tolbutamide treatment on 14C-arachidonic acid conversion to prostacyclin and/or thromboxane in lungs, aortas, and platelets of streptozotocin-induced diabetic rats. STZ
201  1983 In vitro effects of mercury on platelet aggregation, thromboxane and vascular prostacyclin production. PRP
202  1983 In vitro metabolism of 3-t-butyl-4-hydroxyanisole and its irreversible binding to proteins. BHA, CHP, HRP, MC, PB, SSV
203  1983 Influence of aprotinin and gabexate mesilate on arachidonic acid release by the Ca-ionophore A 23187 in the lung. ---
204  1983 Influence of arachidonic acid on vasoconstrictor responses in the rabbit hindquarters vascular bed. ---
205  1983 Influence of endotoxin on arachidonate metabolism in isolated rabbit peritoneum. LPS
206  1983 Influence of propranolol, pindolol, practolol and talinolol on arachidonic acid (AA)- and U-46619-induced aggregation and on AA-induced thromboxane A2 formation in platelets. PRP, TX
207  1983 Involvement of lipoxygenase products in myometrial contractions. OA
208  1983 Lipid bodies: cytoplasmic organelles important to arachidonate metabolism in macrophages and mast cells. ---
209  1983 Lipoxygenase activity in human uterine and intrauterine tissues: new prospects for control of prostacyclin production in pre-eclampsia. 12-HETE, 12-HPETE, NDGA
210  1983 Lipoxygenase inhibitors alter aggregation and adhesiveness of human blood platelets from aspirin-treated patients. ADP, PRP
211  1983 Lipoxygenase pathway in islet endocrine cells. Oxidative metabolism of arachidonic acid promotes insulin release. 12-HETE
212  1983 Lung strips from guinea pigs as test system for lipoxygenase inhibitors. Inhibition of arachidonic acid-induced contractions by 3-t-butyl-4-hydroxyanisole and nordihydroguaiaretic acid. BHA, BHT, NDGA
213  1983 Metabolism of arachidonic acid in vitro by porcine blastocysts and endometrium. MEM
214  1983 Monitoring the entry of new platelets into the circulation after ingestion of aspirin. ADP, PRP
215  1983 Non-estrogenic metabolites of diethylstilbestrol produced by prostaglandin synthase mediated metabolism. PGS
216  1983 Novel hypothalamic arachidonate products stimulate somatostatin release from the median eminence. ETYA, ID, LHRH, ME
217  1983 Platelet aggregability in smoking and non-smoking subjects. PRP
218  1983 Possible role of arachidonic acid and of phospholipase A2 in the control of lysosomal enzyme release from human polymorphonuclear leukocytes. BPB, ETI, PLA2, PMNs
219  1983 Prevention of experimentally induced gastric damage with the tripeptide ZAMI-420, a new thromboxane synthesis inhibitor. PRP, TXA2
220  1983 Prostaglandin biosynthesis by a human macrophage-like cell line, U937. AHG, NDGA, PG, PMA
221  1983 Prostaglandin H2 directly lowers human platelet cAMP levels. PGH2, TXA2
222  1983 Prostaglandin synthesis by microsomes of circular and longitudinal gastrointestinal muscles. PGs
223  1983 Prostaglandins and renin release from submaxillary glands in vitro. EPA, PGs
224  1983 Protection of ischemic cat myocardium by CGS-13080, a selective potent thromboxane A2 synthesis inhibitor. CK, MI, PRP, TXA2, TXB2
225  1983 Release of leukotriene B4 from human neutrophils and its relationship to degranulation induced by N-formyl-methionyl-leucyl-phenylalanine, serum-treated zymosan and the ionophore A23187. Cyt-B, fMLP, LTB4, STZ, TXB2
226  1983 Stimulation of prostaglandin production in rabbit ileal mucosa by bradykinin. PG
227  1983 Studies on the mechanism of antiaggregatory effect of Moutan Cortex. TXB2
228  1983 Studies on the mechanism of human natural killer cell-mediated cytolysis. I. Modulation by dexamethasone and arachidonic acid. DEX, NK
229  1983 Studies on the role of arachidonic acid metabolites in airways contraction induced in vitro by antigen and calcium ionophore A23187. ---
230  1983 Tachyphylaxis in 12-0-tetradecanoylphorbol acetate- and arachidonic acid-induced ear edema. TPA
231  1983 The effects of a mixed fish diet on platelet function, fatty acids and serum lipids. EPA
232  1983 The effects of cigarette smoke on the fate of arachidonic acid in rat and hamster lungs. ---
233  1983 The metabolism of arachidonic acid in isolated perfused fetal and neonatal rabbit lungs. ---
234  1983 The orally active thia-imino-prostacyclin Hoe 892: antiaggregatory and cardiovascular activities. BP
235  1983 The origin of chemiluminescence produced by neutrophils stimulated by opsonized zymosan. cAMP, CL, SOD
236  1983 The role of phosphatidylinositol turnover in initiation of prostaglandin biosynthesis in concanavalin A-induced activation of rat peritoneal macrophages. PA, PI
237  1983 The role of phospholipase C in platelet responses. 1,2-DG, PA
238  1983 The tripeptide ZAMI-420 inhibits thromboxane-induced gastric vasoconstriction and ischaemia. BI, TXA2
239  1983 Thromboxane formation from arachidonic acid and prostaglandin H2 in rabbit spleen. PG, TX
240  1983 Unbalanced plasma control of TxA2 and PGI2 synthesis in vitamin E-deficient rats. MDA, TXB2
241  1983 Uptake of [3H]-arachidonic acid by human endometrium. Differences between normal and menorrhagic tissue. PG
242  1983 [Peroxidation of arachidonic acid and brain edema]. SG
243  1983 [Role of arachidonic acid in platelet aggregation induced by S. typhimurium endotoxin]. PRP
244  1983 [Studies on the inhibitory effect of etafenone hydrochloride on platelet aggregation]. PDE, TX
245  1983 [The modification of the biosynthesis and effect of thromboxane A2 and prostacyclin by trapidil (Rocornal)]. PRP, TXA2
246  1984 2-(6-carboxyhexyl)cyclopentanone hexylhydrazone: a potent inhibitor of the blood platelet cyclo-oxygenase. 13-APA, ADP, CPH, TXB2
247  1984 A proposed method for exploring anti-aggregatory effects of eicosapentaenoic acid in the rat. EPA
248  1984 Activation of phospholipase C in thrombin-stimulated platelets does not depend on cytoplasmic free calcium concentration. ---
249  1984 Activation of prostacyclin synthesis in cultured aortic smooth muscle cells by 'diuretic-antihypertensive' drugs. ---
250  1984 Age-dependent alterations of linoleic, arachidonic and eicosapentaenoic acids in renal cortex and medulla of spontaneously hypertensive rats. EPA, FFA, LA, PC, PE, PUFA, SHR, WR
251  1984 Alterations of linoleic, arachidonic and eicosapentaenoic acids in renal cortex and medulla of SHR during the onset of hypertension. EPA, FFA, LA, PC, PE, SHR
252  1984 An inhibitory effect of arachidonic acid on subsequent responses of canine cerebral arteries to serotonin and other agonists. ---
253  1984 Analysis of leukotrienes, prostaglandins, and other oxygenated metabolites of arachidonic acid by high-performance liquid chromatography. 5S,12S-DiHETE, HHT, LTs, PGs, TXB2
254  1984 Antiinflammatory agents inhibit microvascular permeability induced by leukotrienes and by stimulated human neutrophils. PMN
255  1984 Antiinflammatory aspects of exogenous arachidonic acid. PGE2
256  1984 Arachidonic acid and leukotriene B4 induce aggregation of human peripheral blood mononuclear leucocytes in vitro. LTB4, MNL, PMN
257  1984 Arachidonic acid and postprandial intestinal hyperemia. ---
258  1984 Arachidonic acid metabolism by retinas of rats with streptozotocin-induced diabetes. PGE2
259  1984 Arachidonic acid metabolism in a cell suspension isolated from rabbit renal outer medulla. TALH
260  1984 Arachidonic acid metabolism in purified human lung mast cells. ---
261  1984 Arachidonic acid, 12- and 15-hydroxyeicosatetraenoic acids, eicosapentaenoic acid, and phospholipase A2 induce starfish oocyte maturation. 1-MeAde
262  1984 Arachidonic acid-induced platelet aggregation is mediated by a thromboxane A2/prostaglandin H2 receptor interaction. 13-APA
263  1984 Augmented thromboxane generation by mesenteric arteries from pancreatectomized diabetic dogs is coincident with the vascular tone enhancement evoked by Na arachidonate and prostacyclin. NaA, PGs, TXA2
264  1984 Biosynthesis and biological activity of leukotriene B5. EPA, LTB5, PMN, RP-HPLC, SP
265  1984 Blockade of coronary reactions to arachidonic acid by glyceryl trinitrate and tranylcypromine. GTN, TRC
266  1984 C3-mediated release of prostaglandin from human monocytes. Behaviour in short-term culture. PG, TXB2
267  1984 Characteristics of cyclosporine induction of increased prostaglandin levels from human peripheral blood monocytes. PGE
268  1984 Chronobiological studies on the hypotensive effect of prostaglandin E2 and arachidonic acid in the rat. PGE2
269  1984 Cortical distribution of prostaglandin and renin in isolated dog glomeruli. 6-keto-PGF1 alpha, JM, PGE2, SP
270  1984 Decrease of arachidonic acid in phosphatidylcholine from renal medulla of SHR after feeding a linoleic and linolenic acid-rich diet. EPA, FFA, LAD, LAR, LNA, LNAR, NR, PC, PE, SHR, TG
271  1984 Decrease of platelet aggregation and spreading via inhibition of the cAMP phosphodiesterase by trapidil. PG
272  1984 Defective desaturation and elongation of n-6 and n-3 fatty acids in hypertensive patients. alpha-LNA, EPA, LA
273  1984 Dependence of arachidonic acid (AA) metabolization in human blood platelets on reduced coenzymes. CO, LO
274  1984 Differences in thromboxane production between neonatal and adult platelets in response to arachidonic acid and epinephrine. ---
275  1984 Effect of arachidonic acid metabolism on the release of histamine and SRS (leukotrienes) from guinea-pig lung. ---
276  1984 Effect of dietary depletion and repletion of linoleic acid on renal fatty acid composition and urinary prostaglandin excretion. FFA, LA, PL, UPGE
277  1984 Effect of glucocorticoids on vascular reactivity to vasoactive hormones in rat isolated kidney: lack of relationship to prostaglandins. AII, AVP, BK, NA, PGE2
278  1984 Effect of molsidomine, an anti-anginal drug, on arachidonic acid metabolism in human platelets. ---
279  1984 Effect of orally administered eicosapentaenoic acid (EPA) on the formation of leukotriene B4 and leukotriene B5 by rat leukocytes. EPA, LTB5
280  1984 Effect on nitroglycerin and other organic nitrates on the in-vitro biosynthesis of arachidonic acid-metabolites in washed human platelets. HHT, ISDN, ISMN, MDA, NG
281  1984 Effects of compound 48/80 and formyl-methionyl-leucyl-phenylalanine on isolated guinea pig airways. fMLP
282  1984 Effects of hydrogen peroxide on vascular arachidonic acid metabolism. ---
283  1984 Effects of phospholipase A2, lysophosphatidyl choline, and fatty acid on the acrosome reaction of human spermatozoa. LC, mBWW
284  1984 Effects of the ratio of exogenous eicosapentaenoic acid to arachidonic acid on platelet aggregation and serotonin release. EPA, HETE, TX
285  1984 Effects on glucose-induced insulin secretion of lipoxygenase-derived metabolites of arachidonic acid. 12-HPETE, HETE, LT
286  1984 Endothelial-dependent relaxant effects of vaso-active intestinal polypeptide and arachidonic acid in rat aortic strips. ACh, NA, VIP
287  1984 Evidence for a two-step process in prostaglandin secretion. Intracellular accumulation of prostacyclin precedes its release from human endothelial cells in culture. EC, PGI2
288  1984 Evidence for the involvement of arachidonic acid metabolites in spontaneous and drug-induced contractions of rat urinary bladder. EFAFD, NSAIDs
289  1984 Exercise-induced increase in plasma arachidonic acid and thromboxane B2 in healthy men: effect of beta-adrenergic blockade. PG, TXB2
290  1984 Fibrinogen degradation products influence PGI2 synthesis by cultured porcine aortic endothelial and smooth muscle cells. FDPs, PGI2
291  1984 Glucocorticoid inhibition of zymosan-induced arachidonic acid release by rat alveolar macrophages. ---
292  1984 Human lymphocyte aggregation? ETYA
293  1984 Human mononuclear phagocytes from different anatomical sites differ in their capacity to metabolize arachidonic acid. PG
294  1984 IgE-mediated triggering signals for mediator release from human mast cells and basophils. cAMP
295  1984 In vitro inhibitory effects of an iodinated derivative of arachidonic acid on calf thyroid. IA
296  1984 In vitro investigation on the antiaggregating activity of ditazole. PRP
297  1984 Influence of aspirin, molsidomine, trapidil, and some trapidil derivatives on arachidonic acid induced reversible thrombocyte aggregation in the rabbit. ---
298  1984 Influence of diamide on aggregation, cytoskeletal proteins, and arachidonic acid metabolism in human platelets. TXB2
299  1984 Influence of fenflumizole on platelet aggregation in man. ---
300  1984 Influence of prostaglandins on bovine abomasum: biosynthesis and in vitro motility experiments. HETE's
301  1984 Influence of renal lipoxygenase activity on the renal vascular response to arachidonic acid. ---
302  1984 Influence of trapidil derivatives on arachidonic acid- and prostaglandin endoperoxide analogue- induced platelet aggregation and thromboxane A2 formation. TXA2
303  1984 Influence of verapamil and diltiazem on aggregatory responses in cat and rabbit platelet rich plasma. PGH2
304  1984 Inhibition by ticlopidine of Paf-acether-induced in vitro aggregation of rabbit and human platelets. ADP
305  1984 Inhibition in vitro of platelet aggregation and arachidonic acid metabolism by flavone. ---
306  1984 Inhibition of stimulated prostaglandin biosynthesis by retinoic acid in smooth muscle cells. 6-keto-PGF1 alpha, RA, SMC, TPA
307  1984 Inhibitory activity of indobufen (*) on platelet aggregation in vivo. ASA
308  1984 Lipoxygenase- and cyclooxygenase-reaction products and incorporation into glycerolipids or radiolabeled arachidonic acid in the bovine retina. HETEs, NDGA, PGs
309  1984 Lipoxygenation of arachidonic acid by subcellular preparations from murine keratinocytes. RP, TLC
310  1984 Luminol-dependent chemiluminescence produced by neutrophils stimulated by immune complexes. AHG, CL, IC
311  1984 Macrophage function in the Schistosoma mansoni egg-induced pulmonary granuloma. Role of arachidonic acid metabolites in macrophage Ia antigen expression. Ia, PG
312  1984 Maternal aspirin administration inhibits pulmonary arachidonic acid metabolism in fetal rabbits. ---
313  1984 Mediators of arachidonic acid-induced contractions of indomethacin-treated guinea-pig airways: leukotrienes C4 and D4. ---
314  1984 Modification of platelet aggregation and thromboxane synthesis by intravascular contrast media. ADP, PRP, RCM, TXB2
315  1984 Oxygenation products of arachidonic acid: third messengers for insulin release. ---
316  1984 Paf-acether formation and arachidonic acid freeing from platelet ether-linked glyceryl-phosphorylcholine. GPC
317  1984 Platelet prostanoids in interaction of platelets with collagen substrates. II. Effects of exogenous arachidonic acid, stable PG endoperoxides analogue, and aspirin. CSC
318  1984 Platelet-activating factor is a weak platelet agonist: evidence from normal human platelets and platelets with congenital secretion defects. ADP, PAF
319  1984 Platelets during alimentary hyperlipaemia induced by cream and cod liver oil. FFA
320  1984 Prostacyclin, its fatty acid precursor and its metabolites on the inotropic function of and on the prostanoid generation by diabetic arteries. NaA, TXA2
321  1984 Recycling of platelet phosphorylation and cytoskeletal assembly. ---
322  1984 Reduced glutathione modulates the arachidonic acid induced coronary reactions. PGE2
323  1984 Regulation of B-lymphocyte proliferative responses by arachidonate metabolites: effects on membrane-directed versus intracellular activators. ---
324  1984 Relationship between endogenous prostaglandin E and the vasoconstrictor response to noradrenaline in a perfused arterial segment. NA, PGE
325  1984 Relationship of arachidonic acid metabolism to indomethacin-sensitive immunoregulatory function and lymphocyte PGE sensitivity in peripheral blood mononuclear cells of disseminated solid tumor cancer patients. PBMC
326  1984 Release of prostaglandin E and thromboxane from macrophages by stimulation with factor H. ---
327  1984 Role of calcium in arachidonic acid-induced contractions of guinea pig airways. KHS
328  1984 Role of lipoxygenase products in murine pulmonary granuloma formation. CO, HPLC, Ia, LO, NDGA
329  1984 Secretogogue-stimulated phosphatidylinositol breakdown in the exocrine pancreas liberates arachidonic acid, stearic acid, and glycerol by sequential actions of phospholipase C and diglyceride lipase. DG, LPI, PA, PI, SA, TG
330  1984 Serine esterase inhibitor reduces contractions with isolated trachea and lung strips from guinea pigs induced by phospholipase A2. PLPA2
331  1984 Sex differences in platelet thromboxane and arterial prostacyclin production in control and n-6 fatty acid supplemented rats. PL, PRP, TXB2
332  1984 Smooth muscle contraction as a model to study the mediator role of endogenous lipoxygenase products of arachidonic acid. HETEs
333  1984 Stimulatory effect of lymphocytes from Chagas' patients on spontaneously beating rat atria. ChL, FC, IDT, NL, SRS-A
334  1984 Structural requirements for preventing the aspirin- and the arachidonate-induced inactivation of platelet cyclo-oxygenase: additional evidence for distinct enzymatic sites. ---
335  1984 The combined effects of sodium salicylate, aspirin and indomethacin on the metabolism of arachidonic acid in human platelets. ---
336  1984 The effect of inhibitors on the LTD4-induced contractions and release of thromboxane A2 in the guinea pig lung parenchymal strip. GPLP, IBMX, LT, PLA2, TX, TXB2
337  1984 The effect of plasma on platelet function in hypercholesterolemic rabbits and the changes in fatty acid composition of the plasma. DHA, PRP, WPS
338  1984 The effect of superoxide dismutase and catalase on metabolism of 3H-arachidonic acid by washed platelets. CAT, HPLC, SOD
339  1984 The effect of zinc deficiency on prostaglandin synthesis in rat testes. 6-keto-PGF1 alpha, AL, PF, PGs
340  1984 The effects of arachidonic acid and non-steroidal anti-inflammatory drugs on intrapulmonary airways of the guinea-pig. PGE1
341  1984 The metabolism of arachidonic acid by platelets in nephrotic syndrome. MDA, PAR, PRP, TXB2
342  1984 The mouse ear inflammatory response to topical arachidonic acid. ---
343  1984 The platelet-independent release of thromboxane A2 by Paf-acether from guinea-pig lungs involves mechanisms distinct from those for leukotriene. BK, LTC4, TXA2
344  1984 The role of immunomodulators in the production of lipid mediators by macrophages (M phi). LT, PG
345  1984 The synthesis of cyclooxygenase products in ocular tissues of various species. ---
346  1984 Thromboxane receptor antagonist properties of SQ 27,427 in the anesthetized guinea pig. AZO
347  1984 Time-dependent inhibition of platelet aggregation by dopamine and 3-methoxytyramine. Important roles of their metabolites. 3-MT, ADP, DA, DOPAL, DOPET, MOPAL, MOPET, PRP
348  1984 Ultraviolet radiation induces changes in membrane metabolism of human keratinocytes in culture. ---
349  1984 Uptake and effect on arachidonic acid oxygenation of some icosaenoic acids in human platelets. ---
350  1984 Zinc deficiency affects neither platelet arachidonic acid metabolism nor platelet aggregation in rats. ---
351  1984 [Pressor and depressor responses to intracerebroventricularly administered prostaglandins and arachidonic acid in anaesthetized rabbits]. i.c.v, PG
352  1984 [Synthesis of thromboxane A2: limiting stages of primary thrombocyte aggregation in humans initiated by arachidonic acid and its metabolic products]. PG, TX
353  1984 [The inhibitory effect of oxaprozin, a new non-steroidal anti-inflammatory drug, on platelet aggregation]. PG
354  1984 [Thrombocyte interaction with a collagen substrate: the role of thrombocyte-synthesized prostaglandin endoperoxides and thromboxane A2]. TXA2
355  1985 A new approach to antithrombotic therapy--evaluation of combined therapy of thromboxane synthetase inhibitor and very low dose of aspirin. CVD, TX
356  1985 A novel eicosanoid is the major arachidonic acid metabolite of cultured human monocytes. HPLC, NDGA, TLC
357  1985 A possible mechanism in the anti-anaphylactic effect of beta-adrenoceptor agonists in guinea-pig lungs. TXA2
358  1985 Adrenergic stimulation of prostacyclin production in the rat tail artery. II. The role of calcium. NE
359  1985 Aggregating and prostanoid-releasing effects of platelet-activating factor and leukotrienes on human polymorphonuclear leukocytes and platelets. LTB4, PAF, PMNL
360  1985 Aggregation of and thromboxane B2 synthesis in platelets from newborn infants of smoking and non-smoking mothers. TXB2
361  1985 Alterations in fatty acid composition of murine keratinocytes with in vitro cultivation. FA, FCS, LA
362  1985 Alterations of the eicosanoid synthetic capacity of rat brain microvessels following ischemia: relevance to ischemic brain edema. 15-HPAA, BBB, MCA
363  1985 Altered releasability of vasoactive mediator secreting cells in atopic eczema. ETYA, NDGA
364  1985 An analysis of inhibitory effect of cyclic GMP on arachidonic acid- or collagen-induced aggregation in rabbit platelets. NP
365  1985 An improved malondialdehyde assay for estimation of thromboxane synthase activity in washed human blood platelets. MDA, TBA, TXB2
366  1985 Antagonism of prostaglandin-mediated responses in platelets and vascular smooth muscle by 13-azaprostanoic acid analogs. Evidence for selective blockade of thromboxane A2 responses. APA, HAPA
367  1985 Antiaggregatory effects of thromboxane receptor antagonists in vivo. ---
368  1985 Arachidonic acid metabolism and urinary excretion of prostaglandins and thromboxane in rats with experimental diabetes mellitus. 6-keto-PGF1 alpha, PGs
369  1985 Arachidonic acid metabolism in thrombocytes and vascular tissues of turkeys. HETE, HHT, PG, TXB2
370  1985 Arachidonic acid metabolites induce beta-adrenoceptor desensitization in rat lung in vitro. INDO, ISO
371  1985 Arachidonic acid, an in vivo inhibitor of carrageenin induced granulomas in the rat. 6-keto-PGF1alpha, cAMP, PGE2, TXB2
372  1985 Arachidonic acid-induced aggregation of platelets from human cord blood compared with platelets from adults. ---
373  1985 Arachidonic acid-induced platelet aggregation and prostanoid formation in whole blood in relation to plasma concentration of indomethacin. 6-keto-PGF1 alpha, TXB2
374  1985 Arachidonic acid-related elicitors of the hypersensitive response in potato and enhancement of their activities by glucans from Phytophthora infestans (Mont.) deBary. ---
375  1985 Ascorbic acid enhances the formation of prostaglandin E1 in washed human platelets and prostacyclin in rat aortic rings. ---
376  1985 Beneficial effects of a new potent and specific thromboxane receptor antagonist (SQ-29,548) in vitro and in vivo. ---
377  1985 Binding of iron beads to sialic acid residues on macrophage membranes stimulates arachidonic acid metabolism. ---
378  1985 Blockade of thromboxane and the prevention of eicosanoid-induced sudden death in mice. ---
379  1985 Blood platelet behaviour in mothers and neonates. ---
380  1985 Characterization of a Ca2+-stimulated lipid peroxidizing system in the sea urchin egg. ---
381  1985 Complement- and IgE-mediated release of histamine from basophils in vitro. V. Differential effects of drugs modulating arachidonic acid metabolism. COX, HR, INDO, LPX
382  1985 Contractile responses of the guinea-pig esophageal muscularis mucosae in vitro to arachidonic acid and its metabolites. LT, PG
383  1985 Cyclosporin A inhibits biological effects of tumor promoting phorbol esters. AP, CsA, ODC, TPA
384  1985 Dietary fats and cancer. ALA, EFAs, EPA, GLA, LA, OA, PUFAs
385  1985 Dietary fish oil modulates macrophage fatty acids and decreases arthritis susceptibility in mice. DHA, DPA, DTA, EPA, PG, TX
386  1985 Different effects of centrally acting drugs on rabbit platelet aggregation: with special reference to selective inhibitory effects of antipsychotics and antidepressants. ADP
387  1985 Dihomo-gamma-linolenic acid increases the metabolism of eicosapentaenoic acid in perfused vascular tissue. DGLA, EPA
388  1985 Dynamics of arachidonic acid metabolism in macrophages from delayed-type hypersensitivity (Schistosoma mansoni egg) and foreign-body-type granulomas. mono-HETEs, SE-GM
389  1985 Effect of indomethacin on airway contraction and the release of LTC4-like material. LT, OA
390  1985 Effect of oral administration of arachidonic acid on prostaglandin and zinc metabolism in plasma and small intestine of the rat. ---
391  1985 Effect of pulmonary oedema induced by alpha-naphthylthiourea on synthesis of cyclo-oxygenase products in rat isolated lungs. ANTU
392  1985 Effects of (1,6-di(O-carbamoyl)cyclohexanone oxime)hexane (RHC 80267) on prostaglandin biosynthesis and accumulation of diacylglycerol and arachidonic acid in rabbit iris. DG, PGE2
393  1985 Effects of arachidonate on permeability and resistance distribution in canine lungs. CF, CP, Pc, Rt
394  1985 Effects of arachidonic acid on the metabolism of eicosapentaenoic acid in washed human platelets. EPA, HEPE, PG, TX
395  1985 Effects of dietary fish oil supplementation on the fatty acid composition of the human platelet membrane: demonstration of selectivity in the incorporation of eicosapentaenoic acid into membrane phospholipid pools. EPA, PC, PE, PI, PS
396  1985 Effects of epidermal growth factor, phorbol myristate acetate, and arachidonic acid on choriogonadotropin secretion by cultured human choriocarcinoma cells. EGF, PMA
397  1985 Effects of hydroxyeicosatetraenoic acids on fatty acid esterification in phospholipids and insulin secretion in pancreatic islets. HETE, PC, PE, PI
398  1985 Effects of riboflavin-2', 3', 4', 5'-tetrabutyrate on platelet function and plasma lipids. ---
399  1985 Eicosapentaenoic acid inhibits the release of 14C-prostacyclin from a perfused tissue after incorporation of 14C-prostaglandin precursors. DGLA, EPA, PG, TLC
400  1985 Elevated glucose in vivo and in vitro adversely alters prostaglandin generation in rat aortas and platelets. ---
401  1985 Enhancement of eicosaenoic acid lipoxygenation in human platelets by 12-hydroperoxy derivative of arachidonic acid. 12-HPETE, DHLA, EPA
402  1985 Further studies on the mechanism of action of human plasma in stimulating prostacyclin production by rat smooth muscle cells. ---
403  1985 gamma-Linolenic acid fails to prevent the effects of prenatal ethanol exposure on brain and behavioral development in B6D2F2 mice. GLA
404  1985 Human platelet-derived growth factor stimulates prostaglandin synthesis by activation and by rapid de novo synthesis of cyclooxygenase. PDGF, PG
405  1985 Incorporation into the tissues and turnover of arachidonic acid after administration to normal and essential fatty acid deficient rats. ---
406  1985 Increased arachidonate incorporation in perfused heart phospholipids from vitamin E-deficient rats. ---
407  1985 Increased glomerular thromboxane synthesis as a possible cause of proteinuria in experimental nephrosis. PG, TXA2
408  1985 Influence of the thromboxane antagonist BM 13.177 on the arachidonic acid-induced increase in pulmonary vascular resistance and permeability in rabbit lungs. PG, TX
409  1985 Influence of whole-body gamma irradiation upon arachidonic acid metabolism in rat platelets. TXB2
410  1985 Inhibition by thiamine tetrahydrofurfuryl disulfide (TTFD) of the arachidonic acid cascade-line activation as evidenced in the heart-lung preparation of the dog. CBF, TTFD
411  1985 Inhibition of phospholipase A2 by tiaramide in rabbit platelets. PLA2
412  1985 Intrarenal prostaglandin release: effects of arachidonic acid and hyperchloremia. PGs, RVR
413  1985 Involvement of 5-lipoxygenase metabolites in ACTH-stimulated corticosteroidogenesis in rat adrenal glands. 5-HETE, 5-HPETE, LO, LTB4
414  1985 Involvement of eicosanoids in release of oxytocin and vasopressin from the neural lobe of the rat pituitary. AVP, EETs, PGs
415  1985 Irreversible platelet aggregation does not depend on lipoxygenase metabolites. CO, LO
416  1985 Lipoxygenase products of arachidonic acid stimulate LHRH release from rat median eminence. 12-HETE, GC-MS, MEs, PGE2, rp-HPLC
417  1985 Mechanism of anti-platelet aggregating action of dilazep. TXB2
418  1985 Mechanism of enhancing effect of irradiation on production of IL-2. ---
419  1985 Modulation of mouse ear edema by cyclooxygenase and lipoxygenase inhibitors and other pharmacologic agents. CO, LO, TPA
420  1985 Modulation of vasopressin-induced water permeability of the cortical collecting tubule by endogenous and exogenous prostaglandins. ---
421  1985 Pharmacological modulation of activation-secretion of rat serosal mast cells by chymase, an endogenous secretory granule protease. AH, DDA, DEC, DHA, INDO, NDGA, PGD2, RSMC, THEO
422  1985 Pharmacological modulation of responses of guinea-pig airways contracted with arachidonic acid. NDGA
423  1985 Plasma essential fatty acids in pure and mixed race American Indians on and off a diet exceptionally rich in salmon. EPA
424  1985 Platelet behaviour in normal pregnancy, pregnancy complicated by essential hypertension and pregnancy-induced hypertension. EHT, PIH
425  1985 Platelet desensitization induced by arachidonic acid is not due to cyclo-oxygenase inactivation and involves the endoperoxide receptor. CO, MS, TX
426  1985 Platelet function during continuous insulin infusion treatment in insulin-dependent diabetic patients. CSII, iTXB2, TXA2
427  1985 Platelet survival and function in rats with enhanced thrombotic tendency. ---
428  1985 Possible participation of adenosine 5'-diphosphate, arachidonic acid and paf-acether in the platelet pro-aggregating effect of uncontrolled insulin-dependent diabetic erythrocytes in vitro. ADP, RBC, U.IDD
429  1985 Production of 12-hydroxyeicosatetraenoic acid and vitamin E status in platelets from type I human diabetic subjects. 12-HETE
430  1985 Production of arachidonic acid metabolites by macrophages exposed in vitro to asbestos, carbonyl iron particles, or calcium ionophore. AM, HETE, HHT, LT, TXB2
431  1985 Production of prostaglandin D2 by murine macrophage cell lines. LPS
432  1985 Prostaglandin and thromboxane synthesis by Lewis lung carcinoma during growth. PGE2
433  1985 Prostaglandin synthesis during the course of limb cartilage differentiation in vitro. PGs, RIA, TLC
434  1985 Prostaglandin synthesis from endogenous and exogenous arachidonic acid in the rat uterus. Effect of estradiol and progesterone. PG, Pg
435  1985 Prostaglandins and other arachidonic acid metabolites in the middle ear fluids. HETE, LT, MEF, MOM, PGs, PMN, SOM
436  1985 Prostaglandins and their precursors can modify genetic damage-induced by gamma-radiation and benzo(a)pyrene. BP, GLA, MN, PGs
437  1985 Prostaglandins and thromboxane outflow from the perfused mesenteric vascular bed in spontaneously hypertensive rats. SHR, TXA2
438  1985 Qualitative and quantitative measurement of hydroxy fatty acids, thromboxanes and prostaglandins using stable isotope dilutions and detection by gas chromatography-mass spectrometry. PGs, TXs
439  1985 Rat's vessel wall generates an antiaggregatory substance independent of prostacyclin production. ITRAR, PRP
440  1985 Temporal changes in 12-HETE formation in two models of canine myocardial infarction. 12-HETE, GC-MS, HETEs, PMNs, RP-HPLC
441  1985 The effect of pindolol on exercise-induced increase in plasma vasoactive prostanoids and catecholamines in healthy men. TXB2
442  1985 The effects of amrinone on human platelet aggregation: evidence that amrinone does not act through a cyclic nucleotide mechanism in platelet rich plasma. PGH2
443  1985 The effects of some benzoic acid derivatives on polymorphonuclear leukocyte accumulation in vivo. 2-PBA, 3-MP, 3-PBA, ABA, ASA, PG, PMN
444  1985 The pharmacologic modulation of the release of arachidonic acid metabolites from purified human lung mast cells. 5-HETE, DEC, ETI
445  1985 The positive inotropic effect of sodium arachidonate on auricles from diabetic rats. TX
446  1985 The relative incorporation of arachidonic and eicosapentaenoic acids into human platelet phospholipids. EPA, PC, PE, PI, PS
447  1985 The use of drugs for the inhibition of prostaglandin or leukotriene synthesis from arachidonic acid is theoretically hazardous. DGLA, EPA
448  1985 Thromboxane A2-induced vascular endothelial cell damage and respiratory smooth muscle cell contraction: inhibition by flunarizine, a Ca2+-overload blocker. ---
449  1985 Thromboxane synthase inhibition potentiates washed platelet activation by endogenous and exogenous arachidonic acid. ASA, PG, TX
450  1985 Thromboxane synthase is preferentially conserved in activated mouse peritoneal macrophages. PG
451  1985 Time-dependent inhibition of the cyclooxygenase pathway by 12-hydroperoxy-5,8,10,14-eicosatetraenoic acid. 12-HPETE, HHT, TX
452  1985 Transformations of exogenous arachidonic acid in human platelets in the presence of oleic- and eicosapentaenoic acids. EPA, TXB2
453  1985 [Analgesic asthma]. AIA
454  1985 [Modulation of alveolar macrophage activity by ambroxol, bromhexine and exogenous arachidonic acid]. AM, CL, ROM
455  1985 [Protein binding of thromboxane--one of the sources of error in thromboxane determination]. MDA, TXA2
456  1985 [The modes of anti-inflammatory and analgesic actions of 2-[4-(3-methyl-2-butenyl) phenyl] propionic acid (TA-60) and 2-[4-(2,2-dichlorovinyl) phenyl] propionic acid (TA-668) and effect of TA-60 on the gastrointestinal tract]. ANSAIDs, PGE2
457  1986 9,11-Epoxy-9-homo-14-oxaprosta-5-enoic acid derivatives. Novel inhibitors of fatty acid cyclooxygenase. IND
458  1986 A possible requirement for arachidonic acid lipoxygenation in the mechanism of phagocytic degranulation by human neutrophils stimulated with aggregated immunoglobulin G. AggIgG, LTB4, MPO
459  1986 Activation of NADPH-oxidase by arachidonic acid involves phospholipase A2 in intact human neutrophils but not in the cell-free system. ---
460  1986 Adrenergic and cholinergic stimulation of arachidonate and phosphatidate metabolism in cultured astroglial cells. ACh, PA
461  1986 Alterations in human leukocyte function induced by ingestion of eicosapentaenoic acid. EPA, LTB5, PMN
462  1986 Alterations in prostacyclin and thromboxane formation by chronic cigarette smoke exposure: temporal relationships and whole smoke vs. gas phase. ---
463  1986 Altered 1-14C arachidonic acid metabolism in arterial wall from patients with renal cell carcinoma. 12-HETE, COP and LOP, HPLC, PGE2, PGF2 alpha, TXB2
464  1986 Anesthetics and anticoagulants used in the preparation of rat platelet-rich-plasma alter rat platelet aggregation. A/K, PRP
465  1986 Anti-thrombotic effect of KC-404, a novel cerebral vasodilator. ADP, EEG
466  1986 Arachidonate metabolism in blood cells and the vessel wall. TXA2
467  1986 Arachidonic acid and acetylcholine induced relaxation of bovine coronary artery: effect of indomethacin and methylene blue. ACh, BCA
468  1986 Arachidonic acid induced coronary reactions and their inhibition by docosahexaenoic acid. DHA, LA
469  1986 Arachidonic acid metabolism in human neutrophils: lack of effect of cyclosporine A. CsA
470  1986 Arachidonic acid strongly stimulates prostaglandin I3 (PGI3) production from eicosapentaenoic acid in human endothelial cells. EPA, GC-MS, PGI3
471  1986 Arachidonic acid-induced brain ischaemia: different severity between stroke-resistant spontaneously hypertensive rats and Wistar-Kyoto rats. ICA, SHRSR, WKY
472  1986 Aspirin and dazoxiben as inhibitors of platelet behaviour: modification of their effects by agents that alter cAMP production. PRP
473  1986 Basal phosphatidylinositol turnover controls aortic Na+/K+ ATPase activity. PI
474  1986 Benoxaprofen photosensitization of phospholipase activation in mammalian cells in culture. BPF, UV
475  1986 Bio-synthesis of PGD2 and TXB2 by rabbit blood monocytes. HETE, HHT, HPLC, PG, TX
476  1986 Chronic cyclosporine A treatment reduces prostaglandin E2 formation in isolated glomeruli and papilla of rat kidneys. CyA, KRB, PGE2
477  1986 Comparative antiaggregatory activity in human platelets of a benzopyranone aci-reductone, clofibric acid, and a 2,3-dihydrobenzofuran analogue. ADP
478  1986 Comparative changes in the fatty-acid composition of rat cardiac phospholipids after long-term feeding of sunflower seed oil- or tuna fish oil-supplemented diets. CC, DHA, DPG, EPA, PC, PE, SSO, TFO
479  1986 Comparison of the in vitro effect of eicosapentaenoic acid (EPA)-derived lipoxygenase metabolites on human platelet function with those of arachidonic acid. 12-HEPE, 12-HETE, 12-HPEPE, 12-HPETE, EPA
480  1986 Competition of n-3 and n-6 polyunsaturated fatty acids in the isolated perfused rat heart. EPA
481  1986 Contractile effects of TxA2 and endoperoxide analogues on cultured rat glomerular mesangial cells. CSA, END, PG, PGE2, TXA2
482  1986 Control of gap junction formation in canine trachea by arachidonic acid metabolites. 4-AP, IDM, PG
483  1986 Correlation between mouse skin inflammation induced by arachidonic acid and eicosanoid synthesis. LO, LTC4
484  1986 Cytochrome P-450-dependent monooxygenase activity and endothelial-dependent relaxations induced by arachidonic acid. ---
485  1986 Dazoxiben, UK 38,485 and aspirin: duration of effect for preventing thrombotic sudden death in rabbits. DAZ
486  1986 Deficient induction of leukotriene synthesis in human neutrophils by lipoxygenase-deficient platelets. 12-HPETE, fMLP, LTB4
487  1986 Dermis-derived 15-hydroxy-eicosatetraenoic acid inhibits epidermal 12-lipoxygenase activity. 15-HETE
488  1986 Dietary fat and mammary cancer. II. Modulation of serum and tumor lipid composition and tumor prostaglandins by different dietary fats: association with tumor incidence patterns. HF, LA, PG's
489  1986 Different changes of n-6 and n-3 fatty acids in adipose tissue from spontaneously hypertensive (SHR) and normotensive rats after diets supplemented with linolenic or eicosapentaenoic acids. DHA, DPA, LA, SHR, WKY, WSCHOE
490  1986 Differential effects of diuretics on eicosanoid biosynthesis. FUR, HCT, IND, PGs, SPI
491  1986 Effect of cilostazol on experimental cerebral infarction in rabbits. ASA
492  1986 Effect of serum on the metabolism of exogenous arachidonic acid by phagocytic cells of the mouse thymic reticulum. P-TR
493  1986 Effects of 2-indolecarbohydrazides on thromboxane synthetase activity and on in vitro and ex vivo blood platelet aggregation. New selective inhibitors. ADP, PGE2, TXB2
494  1986 Effects of a thromboxane synthetase inhibitor and a cAMP phosphodiesterase inhibitor, singly and in combination, on platelet behaviour. PRP
495  1986 Effects of arachidonic acid and indomethacin on sister-chromatid exchange induction by polycyclic aromatic hydrocarbons in mammalian cell lines. AHH, BP, DMBA, IM, PES, SCE
496  1986 Effects of dietary supplementation of fish oil on neutrophil and epidermal fatty acids. Modulation of clinical course of psoriatic subjects. ---
497  1986 Effects of dipyridamole, nifedipine, verapamil, hydralazine and propranolol on the formation of prostacyclin and thromboxane in a coupled system of platelets and aorta. ---
498  1986 Effects of ocular inflammation on tear proteins. I. Thiol protease inhibitors. ---
499  1986 Effects of verapamil on activation of arachidonic acid metabolism in guinea-pig lungs. LTE4, TXA2
500  1986 Effects of Y-20811, a long-lasting thromboxane synthetase inhibitor, on thromboxane production and platelet function. TX
501  1986 Eicosapentaenoic acid as a modulator of inflammation. Effect on prostaglandin and leukotriene synthesis. EPA, LTB4, PGs
502  1986 Endothelium-dependent inhibition of platelet aggregation. ACh, EDRF, NA, NDGA
503  1986 Fibronectin decreases pulmonary vascular permeability under baseline conditions and after administration of arachidonic acid in rabbit lungs. CFC, KHB
504  1986 Functional significance of exaggerated renal thromboxane A2 synthesis induced by cyclosporin A. CyA, GFR, PGE2, TX
505  1986 Generation of the arachidonic acid metabolite 8-HETE by extracts of mouse skin treated with phorbol ester in vivo; identification by 1H-n.m.r. and GC-MS spectroscopy. 8-HETE, RPA, TPA
506  1986 High-performance liquid chromatographic analysis of arachidonic acid metabolites by pre-column derivatization using 9-anthryldiazomethane. HPLC
507  1986 In vitro generation of chemotactic leukotrienes from unfractionated murine epidermal cells. HPLC, LTs, RIAs
508  1986 In vitro synthesis of 12-hydroxy-eicosatetraenoic acid is increased in uninvolved psoriatic epidermis. 15-HETE, LTB4
509  1986 Increased biosynthesis of lipoxygenase products by UVB-irradiated guinea pig epidermis: evidence of a cyclooxygenase inhibitor. ---
510  1986 Increased lung vascular permeability after arachidonic acid and hydrostatic challenge. ---
511  1986 Increased mole fraction of arachidonic acid in bronchial phospholipids in patients with cystic fibrosis. CF
512  1986 Inhibition of eicosanoid formation by prazosin in the rabbit renal cortex. RP-HPLC, TLC
513  1986 Inhibition of platelet aggregation in whole blood by dipyridamole and aspirin. PAF
514  1986 Inhibition of prostacyclin synthesis in cultured bovine aortic endothelial cells by vitamin K1. PGE2, PGH2
515  1986 Inhibition of prostaglandin biosynthesis by SQ 28,852, a 7-oxabicyclo[2.2.1]heptane analog. PG, TX
516  1986 Inhibition of the antidiuretic hormone hydroosmotic response by phospholipids and phospholipid metabolites. ADH, PG
517  1986 Inhibition of the effects of thrombin on guinea pig platelets by the diacylglycerol lipase inhibitor RHC 80267. DGL, PLA2, PLC
518  1986 Inhibitory effects of three new synthetic compounds on human platelet aggregation. ADP, PRP
519  1986 Involvement of lipoxygenase products of arachidonic acid metabolism in bovine luteal function. 5-HETE, CL, NDGA, PG
520  1986 Leukotriene modulation of chloride transport in frog cornea. CO, LO, LTB4, LTC4, LTs, PD, SCC, TLC
521  1986 Linoleic and dihomo-gamma-linolenic acids modulate granuloma growth and granuloma macrophage eicosanoid release. DHGLA, FA, LA, PG, TX
522  1986 Lipid composition of cultured murine keratinocytes. AC, AGC, LA
523  1986 LPS-stimulated release of prostaglandin E and thromboxane B2 from the U937 cell line. LPS, PGE, PMA, TXB2
524  1986 Modulation by cyclic AMP of arachidonic acid-induced platelet desensitization. cAMP
525  1986 Modulation of lymphocyte responsiveness to phytohemagglutinin by micromolecular fibrinogen degradation products. FDP, PBMC, PHA
526  1986 Modulation of the population density of identifiable epidermal Langerhans cells associated with enhancement or suppression of cutaneous immune reactivity. MBEH
527  1986 Onion exerts antiaggregatory effects by altering arachidonic acid metabolism in platelets. ---
528  1986 Pancreatic islet arachidonic acid turnover and metabolism and insulin release in response to delta-9-tetrahydrocannabinol. 12-HETE, THC
529  1986 Perfused and ventilated guinea-pig lung: a method for evaluating xenobiotic effects on arachidonic acid using formaldehyde. LT, TX
530  1986 PGI2 synthesis and excretion in dog kidney: evidence for renal PG compartmentalization. BK, PG
531  1986 Pharmacological studies on proglumetacin maleate, a new non-steroidal anti-inflammatory drug (4). Mode of action on anti-inflammatory activity. DPP, IND, PGM, SAA
532  1986 Phospholipase inhibition and prostacyclin generation by gastric muscularis and mucosa layers. APP, PLA2
533  1986 Physiology and pharmacology of prostaglandins. PGs, TXA2
534  1986 Plasma-free eicosapentaenoic acid/arachidonic acid ratio: a possible new coronary risk factor. EPA, FFA, HDL
535  1986 Platelet aggregating substance from mononuclear leukocytes. ETYA, ML, NDGA, TXA2
536  1986 Platelet antiaggregatory substances inhibit arachidonic acid induced coronary constriction. DPY, HYD, MIX, NFP
537  1986 Platelet formation of 12-hydroxyeicosatetraenoic acid and thromboxane B2 is increased in type IIA hypercholesterolemic subjects. 12-HETE, PRP, SIM, TXB2
538  1986 Potentiation with epinephrine of macaque platelet aggregation by other agonists: implications for studies on human atherosclerosis. ---
539  1986 Prostacyclins are only weak antagonists of coronary vasospasm induced by authentic thromboxane A2 and serotonin. BCA, TX, WPS
540  1986 Prostaglandin and thromboxane biosynthesis in resting and activated platelet-free monocytes from aged subjects. PGE2, TXA2
541  1986 Prostaglandin production in cultured gastric mucosal cells: role of cAMP on its modulation. TXA2
542  1986 Prostaglandins as endogenous mediators of interleukin 1 production. CO, IL-1, LPS, PGE2, PGI2
543  1986 Protein phosphorylation and oocyte maturation. II. Inhibition of starfish oocyte maturation by intracellular microinjection of protein phosphatases 1 and 2A and alkaline phosphatase. 1-MeAde, 8-HETE, DTT, MGBG, MPF
544  1986 Pulmonary microvascular responses to arachidonic acid in isolated perfused guinea pig lung. Rv
545  1986 Putative roles for lysophospholipids as mediators and lipoxygenase-mediated metabolites of arachidonic acid as potentiators of stimulus-secretion coupling: dual mechanisms of p-hydroxymercuribenzoic acid-induced insulin release. lysoPL, PHMB
546  1986 Regulation of prostacyclin production by vascular cells in in vitro and in vivo experimentals systems. ---
547  1986 Release of leukotriene B4 and 5-hydroxyeicosatetraenoic acid during phagocytosis of artificial immune complexes by peripheral neutrophils in chronic inflammatory bowel disease. 5-HETE, ICs, LTB4
548  1986 Remodeling of arachidonate-containing phosphoglycerides within the human neutrophil. PC, PE, PI
549  1986 Renal prostaglandin efflux induced by vasopressin, dDAVP and arachidonic acid: contrasting profile and sites of release. AVP, DDAVP, PG, RIA, UE, VE
550  1986 RU486 antagonizes the inhibitory action of progesterone on prostacyclin and thromboxane A2 synthesis in cultured rat myometrial explants. TXA2
551  1986 Salicylate antagonism of acetylsalicylic acid inhibition of platelet aggregation in male and female subjects: influence of citrate concentration. ASA, SA
552  1986 Slow desaturation and elongation of linoleic and alpha-linolenic acids as a rationale of eicosapentaenoic acid-rich diet to lower blood pressure and serum lipids in normal, hypertensive and hyperlipemic subjects. EPA, HLP, LA, LNA
553  1986 Specific inhibition of PAF-acether-induced platelet activation by BN 52021 and comparison with the PAF-acether inhibitors kadsurenone and CV 3988. ADP
554  1986 Stimulation of arachidonic acid release and eicosanoid biosynthesis in an interleukin 2-dependent T cell line. ---
555  1986 Stimulation of superoxide release in neutrophils by 1-oleoyl-2-acetylglycerol incorporated into pH-sensitive liposomes. OAG, PE
556  1986 Studies on a modulatory role for adenosine in antigen and arachidonic acid induced contractions of guinea pig airways. R-PIA
557  1986 Substrate for endothelial prostacyclin production in the presence of platelets exposed to collagen is derived from the platelets rather than the endothelium. HUVECs, PAF, TXA2
558  1986 The effect of macrophage development on the release of reactive oxygen intermediates and lipid oxidation products, and their ability to induce oxidative DNA damage in mammalian cells. BCG, NDGA, ROI
559  1986 The effect of nifedipine, nimodipine and nisoldipine on agonist- and trauma-stimulated vascular prostacyclin synthesis in vitro. ---
560  1986 The effect of sodium intake on renal prostaglandin production. PG, PRA
561  1986 The influence of dietary manipulation with n-3 and n-6 fatty acids on liver and plasma phospholipid fatty acids in rats. DGLA, DHA, EPA, EPO, LA, POL
562  1986 The production of hydroxyl radical by human neutrophils stimulated by arachidonic acid--measurements by ESR spectroscopy. DMPO, ESR
563  1986 The relative degradation of [14C]eicosapentaenoyl and [3H]arachidonoyl species of phosphatidylinositol and phosphatidylcholine in thrombin-stimulated human platelets. DG, EPA, PA, PC, PI, TFP, TX
564  1986 Thromboxane synthase inhibition: implications for prostaglandin endoperoxide metabolism. I. Characterisation of an acute intravenous challenge model to measure prostaglandin endoperoxide metabolism. RIA, RP-HPLC, TxSI
565  1986 Topical steroid treatment reduces arachidonic acid and leukotriene B4 in lesional skin of psoriasis. 12-HETE, LTB4, PGE2
566  1986 Uptake of fatty acids and their mobilization from phospholipids in cultured monocyte-macrophages from rheumatoid arthritis patients. DHLA, FA, LA, PBM, PC, PG, PL, PM phi, RA
567  1986 Use of plasma for immediate diagnosis of multiple sclerosis (plasma-erythrocyte unsaturated fatty acid test): comparison with the erythrocyte-unsaturated fatty acid (E-UFA) test. E-UFA, LA, OND, RBC
568  1986 [Effect of bilateral common carotid artery ligation on prostaglandin levels (TXA2, PGI2) in spontaneously hypertensive rats (SHRSP, SHRSR) and normotensive rats (WKY)]. BLCL, PGs, SHRSP, SHRSR, TXA2, TXB2, WKY
569  1986 [Metabolism of arachidonic acid in the thrombocytes of patients with periodic disease]. 12-HETE, FMF, HHT
570  1986 [Pharmacological studies on ginger. IV. Effect of (6)-shogaol on the arachidonic cascade]. PGI2
571  1986 [The effect of ambroxol and bromhexine on the "respiratory burst" of alveolar macrophages]. AM, CL, ROM
572  1987 13-Hydroxyoctadecadienoic acid (13-HODE) stimulates prostacyclin production by endothelial cells. 13-HODE
573  1987 A novel arachidonic acid metabolite with stimulatory effect on PHA-induced mitogenesis of lymphocytes. PBML
574  1987 A novel synthetic vitamin A-like compound (a polyprenoic acid derivative, E-5166) inhibits the release of arachidonic acid stimulated by epidermal growth factor. EGF, PI
575  1987 A role for ca in the elicitation of rishitin and lubimin accumulation in potato tuber tissue. PL
576  1987 Abnormal metabolism of arachidonic acid in chronic inflammatory bowel disease: enhanced release of leucotriene B4 from activated neutrophils. 5-HETE, HHT, LTB4
577  1987 Abnormal metabolism of polyunsaturated fatty acids and phospholipids in diabetic glomeruli. FFA, LA, PE
578  1987 Alpha 1-adrenergic receptor induced subsensitivity and supersensitivity in rabbit iris-ciliary body. Effects on myo-inositol trisphosphate accumulation, arachidonate release, and prostaglandin synthesis. DG, PG
579  1987 Alteration of mercuric chloride-induced autoimmune glomerulonephritis in brown-Norway rats by herring oil, evening primrose oil and OKY-046 a selective TXA-synthetase inhibitor. BM, BN, BW, EPA, EPO, FT, GLNA, GN, HO, LA, MC, PGs, s.c
580  1987 Altered intraplatelet arachidonic acid metabolism during the acute state of unstable angina. TXA2
581  1987 Arachidonic acid and 15(S)-hydroxy-5,8,11-cis-13-trans-eicosatetraenoic acid modulate human polymorphonuclear neutrophil activation by monocyte derived neutrophil activating factor. 15-HETE, LTB4, NAF, PMN
582  1987 Arachidonic acid and LTB4 enhance aggregation of psoriatic peripheral blood mononuclear leukocytes in vitro. ASA, LTB4, MNL, NDGA
583  1987 Arachidonic acid and male genital differentiation. ---
584  1987 Arachidonic acid and pulmonary function in heart-lung-preparation of guinea-pig: modulation by PCO2. HLPs
585  1987 Arachidonic acid is involved in the regulation of hCG induced steroidogenesis in rat Leydig cells. ETYA, NDGA, PLC
586  1987 Arachidonic acid lipoxygenase pathways and increased vascular permeability in isolated rabbit lungs. ---
587  1987 Arachidonic acid metabolic profiles in human meningiomas and gliomas. ---
588  1987 Arachidonic acid metabolism in alveolar macrophages. A comparison of cells from healthy subjects, allergic asthmatics, and chronic bronchitis patients. AM
589  1987 Arachidonic acid metabolism is altered in sarcoid alveolar macrophages. AMs, HETEs, LT, PG, TXB2
590  1987 Arachidonic acid protection of rat mucosa against stress ulceration. NS
591  1987 Arachidonic acid stimulation of mucus production by rat gastric cultured cells. ---
592  1987 Arachidonic acid-induced pleurisy (ARIP): an in vivo model for testing 5-lipoxygenase inhibition. ARIP
593  1987 Arachidonic and eicosapentaenoic acid metabolism in bovine neutrophils and platelets: effect of calcium ionophore. 5-HEPE, 5-HETE, EPA, HHT, LTB4, LTB5, TXB2
594  1987 Assessment of leukotriene B4 synthesis in human lymphocytes by using high performance liquid chromatography and radioimmunoassay methods. HPLC, LT, RIA
595  1987 Biphasic effect of oxygen radicals on prostaglandin production by rat mesangial cells. PGE2, ROS
596  1987 Blockade of thromboxane responses in the airway of the cat by SQ 29,548. ---
597  1987 Bovine placental prostaglandin synthesis in vitro as it relates to placental separation. PG's
598  1987 C3-mediated release of prostaglandin from human monocytes: evidence for independent regulation of thromboxane and prostaglandin synthesis. HMP
599  1987 Calcium ionophore (A23187)- and arachidonic acid-stimulated prostaglandin release from microvascular endothelial cells: effects of calcium antagonists and calmodulin inhibitors. PG, PL, RCME
600  1987 cAMP levels from endogenous and exogenous arachidonic acid in isolated dog lung. cAMP
601  1987 CGS 15435A, a thromboxane synthetase inhibitor with an extended duration of action: a comparison with dazoxiben. DAZ, TX
602  1987 Changes in cyclic 3'5'-adenosine monophosphate tissue concentration and net fluid transport in the cat's small intestine elicited by cholera toxin, arachidonic acid, vasoactive intestinal polypeptide and 5-hydroxytryptamine. 5-HT, cAMP, VIP
603  1987 Changes of N-6 and N-3 fatty acids in liver from spontaneously hypertensive (SHR) and normotensive rats after diets supplemented with alpha-linolenic or eicosapentaenoic acids. DHA, FFA, LA, PC, PE, SHR, TG
604  1987 Cholinergic and non-cholinergic components of the inotropism evoked by electric field stimulation in the isolated rat urinary bladder. Influence of some eicosanoids. ACh, ASA, EFS, NDGA
605  1987 Comparison of histamine release and prostaglandin E2 production of human basophils in atopic and normal individuals. ASA, HR
606  1987 Comparison of subcellular activation of the human neutrophil NADPH-oxidase by arachidonic acid, sodium dodecyl sulfate (SDS), and phorbol myristate acetate (PMA). PKC, PMA, SDS
607  1987 Conversion of linoleic acid into arachidonic acid by cultured murine and human keratinocytes. LA
608  1987 Copper modulation of macrophage cyclooxygenase metabolite synthesis. GUR, PG, TX
609  1987 Cyclic AMP-dependent regulation of lipid mediators in white cells. A unifying concept for explaining the efficacy of theophylline in asthma. LT, PG, PGE
610  1987 Cytochrome P-450-related arachidonic acid metabolites. ---
611  1987 Decreased plasma arachidonic acid binding capacity in neonates. RDS
612  1987 Detection of sputum eicosanoids in cystic fibrosis and in normal saliva by bioassay and radioimmunoassay. CF, LTs, PGE2, PGF2 alpha, Ps, RIA, SRSs, TXB2
613  1987 Differential effects of estradiol, arachidonic acid, and A23187 on prostaglandin F2 alpha output by epithelial and stromal cells of human endometrium. PGF2 alpha
614  1987 Differential influence of calcium channel-blockers on prostanoid generation and thromboxane-mediated vasoconstriction in rabbit lungs. ---
615  1987 Differential inhibitory effects of auranofin on leukotriene B4 and leukotriene C4 formation by human polymorphonuclear leukocytes. AF, LT, PMNs
616  1987 Digestion, absorption and effects on cholesterol absorption of menhaden oil, fish oil concentrate and corn oil by rats. EPA, FOC
617  1987 Dynamic actions of arachidonic acid and protein kinase C in pituitary stimulation by gonadotropin-releasing hormone. TPA
618  1987 Effect of diltiazem on intracellular Ca2+ mobilization in hepatocytes during endotoxic shock. ---
619  1987 Effect of effervescent buffered aspirin on prostaglandin synthesis by human gingival fibroblasts. EBA
620  1987 Effect of selected antiinflammatory agents and other drugs on zymosan, arachidonic acid, PAF and carrageenan induced paw edema in the mouse. CO, LO, PAF
621  1987 Effect of single-dose aspirin on TXA2 and PGI2 cyclooxygenases in vivo. 6-keto PGF1 alpha, TXA2, TXB2
622  1987 Effects of A23187, exogenous phospholipase A2 and exogenous arachidonic acid on pulmonary vascular resistance in isolated rabbit lung. PLA2, PVR, TXA2
623  1987 Effects of chronic ethanol ingestion on arachidonic acid metabolism in rat tissues and in vitro effect of ethanol on cAMP in platelets. 5-HETE, cAMP, LTB4
624  1987 Effects of selenium, vitamin E and vitamin C on human prostacyclin and thromboxane synthesis in vitro. TBHP, TXA2
625  1987 Eicosanoid production by the coronary microvascular endothelium. PG, RCME
626  1987 Eicosapentaenoic acid metabolism in cynomolgus and rhesus conjunctiva and eyelid. ---
627  1987 Endothelium, arachidonic acid, and coronary vascular tone. EDRFs, TXA2
628  1987 Enhanced capacity for release of leucotriene B4 by neutrophils in rheumatoid arthritis. LTB4
629  1987 Epoxy derivatives of arachidonic acid are potent stimulators of prolactin secretion. 5,6-EET, 5-HETE, EH, PRL
630  1987 Estradiol enhances prostaglandin synthase activity in epithelial but not in stromal cells of human endometrium. ---
631  1987 Evidence for increased activity of mouse brain fatty acid cyclooxygenase following drug-induced convulsions. PGE2, PGF2 alpha, PGs, PTZ
632  1987 Evidence that renal prostaglandin and thromboxane production is stimulated in chronic cyclosporine nephrotoxicity. ---
633  1987 Fasting and diabetes mellitus elicit opposite effects on agonist-stimulated prostacyclin synthesis by the rat aorta. ---
634  1987 Fatty acids, cholesterol, and their roles in ischemia. ---
635  1987 Hemorheological changes in elderly subjects--effect of pentosan polysulfate and possible role of leucocyte arachidonic acid metabolism. PPS
636  1987 Heterogeneous distribution of lipoxygenase products in psoriatic skin lesions. HETE, LTB4
637  1987 Homologous desensitization to prostaglandins in rabbit ileum. cAMP, Isc, PG's, VIP
638  1987 Human neutrophil activation with interleukin-1. A role for intracellular calcium and arachidonic acid lipoxygenation. CTC, ETYA, IL-1, NDGA
639  1987 Human polymorphonuclear neutrophil activation with arachidonic acid. CB, DIDS, ETYA, PKC, PMNs
640  1987 In vitro effect of cinnamic aldehyde, a main component of Cinnamomi Cortex, on human platelet aggregation and arachidonic acid metabolism. TXB2
641  1987 Incomplete biochemical adaptation of vein grafts to the arterial environment in terms of prostacyclin production. ---
642  1987 Increased prostaglandin formation in rat brain following systemic application of kainic acid. PGD2, PGE2, PGF2 alpha, TXB2, WDS
643  1987 Indomethacin reduces proteinuria in passive Heymann nephritis in rats. ADR, GFR, i.p, i.v, PGs, PHN, TX
644  1987 Inflammation, oxidative DNA damage, and carcinogenesis. TPA
645  1987 Influence of some beta blockers (pindolol, atenolol, timolol and metoprolol) on aggregation and arachidonic acid metabolism in human platelets. CO
646  1987 Inhibition by methylprednisolone of zymosan-induced leukotriene synthesis in alveolar macrophages. AMs, GC, LT, MP, TXB2
647  1987 Inhibition by Salicylhydroxamic Acid, BW755C, Eicosatetraynoic Acid, and Disulfiram of Hypersensitive Resistance Elicited by Arachidonic Acid or Poly-l-Lysine in Potato Tuber. ETYA, SHAM
648  1987 Inhibition of lipoxygenase products by retinoids in human blood cells. ---
649  1987 Inhibition of platelet aggregation and reduced formation of thromboxane and lipoxygenase products in platelets by oil of cloves. ---
650  1987 Inhibition of platelet aggregation by myeloid leukaemic cells demonstrated in vitro. ADP, PMN
651  1987 Inhibition of thromboxane A2 production by trapidil and trapidil derivatives in the arachidonic acid-injected rat. TXA2
652  1987 Inhibitors of diacylglycerol lipase and diacylglycerol kinase inhibit carbamylcholine-stimulated responses in guinea pig pancreatic minilobules. CCh, DG
653  1987 Inhibitors of prostaglandin dehydrogenase (Ph CL 28A and Ph CK 61A) increase output of prostaglandins from rat isolated lung. PGDH, PGE2
654  1987 Inhibitory effect of sulindac on prostaglandin synthesis in cultured renal and vascular cells. NSAID, PG
655  1987 Injection of tridocosahexaenoyl-glycerol emulsion and fatty acid composition of blood cells. DHA, EPA
656  1987 Interference of the thromboxane antagonist SK&F 88046 with platelet activation and subsequent desensitization by arachidonic acid and the thromboxane mimetics U46619 and EP171. ---
657  1987 Kinetic studies on the inactivation of 5-lipoxygenase by 5(S)-hydroperoxyeicosatetraenoic acid. 5-HETE, 5-HPETE, DTT
658  1987 Leukocyte-derived metabolites of arachidonic acid in ischemia-induced myocardial injury. PMNs
659  1987 Lipoxygenase inhibitors suppress IL-2 synthesis: relationship with rise of [Ca++]i and the events dependent on protein kinase C activation. IL-2, LO, PKC
660  1987 Low prevalences of coronary heart disease (CHD), psoriasis, asthma and rheumatoid arthritis in Eskimos: are they caused by high dietary intake of eicosapentaenoic acid (EPA), a genetic variation of essential fatty acid (EFA) metabolism or a combination of both? CHD, DGLA, EFA, EPA
661  1987 Metabolism of arachidonic acid in human lung cancer cell lines. PGE2
662  1987 Metabolism of [14C]arachidonic acid by polymorphonuclear leukocytes in patients with psoriasis. ---
663  1987 Modulation of prostaglandin synthesis in mouse peritoneal macrophages by enrichment of lipids with either eicosapentaenoic or docosahexaenoic acids in vitro. 6 keto PGF1 alpha, DHA, EPA, PGE2, PUFA, TXB2
664  1987 Muscarinic cholinergic induced subsensitivity in rabbit iris-ciliary body. Effects on myo-inositol triphosphate accumulation, arachidonate release, prostaglandin synthesis, and contraction. IP3, MLC, PG, PPI
665  1987 Partial characterization of phospholipase C activity in normal, psoriatic uninvolved, and lesional epidermis. ---
666  1987 Permeability and vasomotor response of cerebral vessels during exposure to arachidonic acid. FITC
667  1987 PGI3 production from eicosapentaenoic acid in 3T3 fibroblast cells and cultured bovine pulmonary artery endothelial cells. CPAE, EPA, GC-MS, TLC
668  1987 Pharmacological modulation of bradykinin-, acetylcholine- and calcium ionophore A23187-induced relaxation of rabbit pulmonary arterial segments. ACh, BK, EDRF
669  1987 Phorbol ester-induced formation of clastogenic factor from human monocytes. PMA
670  1987 Phospholipase A2 activation in chemotactic peptide-stimulated HL60 granulocytes: synergism between diacylglycerol and Ca2+ in a protein kinase C-independent mechanism. fMLP, OAG
671  1987 Phospholipase A2 treatment of lymphocytes provides helper signal for interferon-gamma induction. Evidence for second messenger role of endogenous arachidonic acid. IFN-gamma, PLA2, PLC
672  1987 Phospholipid and arachidonic acid metabolism in zymosan-stimulated human monocytes: modulation by cAMP. dcAMP, IBMX, PC, PI
673  1987 Platelet aggregation in whole blood from patients with Glanzmann's thrombasthenia. PRP
674  1987 Possible role of endothelial thromboxane A2 in the resting tone and contractile responses to acetylcholine and arachidonic acid in canine cerebral arteries. ACh, iTxB2, TXA2
675  1987 Potential inhibitors of platelet aggregation from plant sources, III. DBA
676  1987 Preparative HPLC purification of prostaglandin endoperoxides and isolation of novel cyclooxygenase-derived arachidonic acid metabolites. 15-HETE, 15-HPETE, PGG2, PGH2
677  1987 Prostaglandin and thromboxane synthesis by M5076 ovarian reticulosarcoma during growth: effects of a thromboxane synthetase inhibitor. 6-keto-PGF1 alpha, PGD2, PGE2, PGF2 alpha, TXB2
678  1987 Prostaglandin metabolism in umbilical vessels of smoking and non-smoking mothers. PG, TLC
679  1987 Prostaglandin synthesis by squamous carcinoma cells of head and neck, and its inhibition by non-steroidal anti-inflammatory drugs. PGs, SCC
680  1987 Prostaglandin synthesis in human T cells: its partial inhibition by lectins and anti-CD3 antibodies as a possible step in T cell activation. mAb, PG, TPA
681  1987 Prostaglandin-H-synthase competent cells derived from ram seminal vesicles: a tool for studying cooxidation of xenobiotics. PG, PHS, SEMV
682  1987 Protective effect of gamma-linolenic acid on aspirin-induced gastric hemorrhage in rats. GLA
683  1987 Purified human basophils do not generate LTB4. ---
684  1987 Release of arachidonic acid metabolites by human monocytes or lymphocytes: effect of treatment with interferon on stimulation by phorbol ester or calcium ionophore. HETE, HHT, IFN, LTB4, TPA
685  1987 Release of renin and angiotensin II into plasma and lymph during hyperchloremia. Ang II, LR, RR, RVR
686  1987 Reversible activation of NADPH oxidase in membranes of HL-60 human leukemic cells. CF
687  1987 Role of arachidonic acid release in the G2 delay induced by tumor promoter TPA in HeLa cells. ---
688  1987 Septic lung. ---
689  1987 Specific action of the lipoxygenase pathway in mediating angiotensin II-induced aldosterone synthesis in isolated adrenal glomerulosa cells. 12-HETE, AII, CO, LO
690  1987 Starfish oocyte maturation: 1-methyladenine triggers a drop of cAMP concentration related to the hormone-dependent period. 1-MeAde, 8-HETE, HDP
691  1987 Stimulus-specific induction of phospholipid and arachidonic acid metabolism in human neutrophils. DAG, PI, PLA2, PLC
692  1987 Suppression of the cutaneous immune response following topical application of the prostaglandin PGE2. CHS, DNFB, IM
693  1987 Surfactant-induced alteration of arachidonic acid metabolism of mammalian cells in culture. AEOS, LAS
694  1987 Synthesis of slow-reacting substance-like activity in human anterior uvea. GI, SRS
695  1987 The action of erythropoietin is mediated by lipoxygenase metabolites in murine fetal liver cells. 12-HETE, 15-HETE, Ep
696  1987 The antiinflammatory action of guanabenz is mediated through 5-lipoxygenase and cyclooxygenase inhibition. LT, PG, TPA
697  1987 The effect of dietary eicosapentaenoic acid on arachidonic acid incorporation and metabolism in rat leukocytes. EPA
698  1987 The effect of modulating the synthesis of arachidonic acid cascade products on HSV lesion recurrence. PRI
699  1987 The influence of fenflumizole on platelet aggregation in patients with unstable angina pectoris. beta-TG, PF4, TXB2
700  1987 The pharmacology of arachidonic acid-induced rat paw edema. ---
701  1987 The platelet cyclooxygenase metabolite 12-L-hydroxy-5, 8, 10-hepta-decatrienoic acid (HHT) may modulate primary hemostasis by stimulating prostacyclin production. FBAECs
702  1987 The use of 12-hydroxyheptadecatrienoic acid (HHT) as an HPLC/spectrophotometric marker for cyclooxygenase pathway activity in resident rat peritoneal cells. 5-LO, CO, HHT
703  1987 Therapeutic potential of choline magnesium trisalicylate as an alternative to aspirin for patients with bleeding tendencies. CMT
704  1987 Uptake and distribution of cis-unsaturated fatty acids and their effect on free radical generation in normal and tumor cells in vitro. c-UFAs, EPA, LA
705  1987 Vascular lipoxygenase activity: synthesis of 15-hydroxyeicosatetraenoic acid from arachidonic acid by blood vessels and cultured vascular endothelial cells. EC
706  1987 Vasoactivity of arachidonic acid epoxides. ---
707  1987 [A study on the activity of the PGI2 producing enzyme system derived from maternal and fetal vessels of toxemia of pregnancies]. NOR, O.V, TOX, UV
708  1987 [Different severity of brain ischemia between spontaneously hypertensive rats and Wistar-Kyoto rats induced by internal carotid infusion of arachidonic acid]. SEM, SHRSR, WKY
709  1987 [Effect of SIN-1 on the synthesis of leukotrienes in human polymorphonuclear cells]. LT, PMNL
710  1987 [Effects of SIN-1, a metabolite of molsidomine, on paf-acether-blood platelets interactions]. ADP
711  1987 [Studies on a platelet aggregation inhibitor isolated from the human placenta]. PCO, TXB2
712  1988 A comparison of the effect of timegadine, levamisole, and D-penicillamine on human neutrophil metabolism of endogenous arachidonic acid and chemotaxis. LTB4
713  1988 A study on cisternal CSF levels of arachidonic acid metabolites after aneurysmal subarachnoid hemorrhage. ---
714  1988 Acetaminophen and analogs as cosubstrates and inhibitors of prostaglandin H synthase. BHA, NAPQI, PGHS
715  1988 Albumin in monocyte function assays. Differential stimulation of superoxide or arachidonate release by calcium ionophores. TPA
716  1988 Altered arachidonic acid metabolism and platelet size in atopic subjects. ---
717  1988 Arachidonic acid metabolism and casein secretion in lactating rabbit mammary epithelial cells: effects of inhibitors of prostaglandins and leukotrienes synthesis. DCHA, GST, PGF2 alpha, PRL
718  1988 Arachidonic acid metabolism in Ascidia ceratodes eggs: role of lipid peroxidation. ---
719  1988 Arachidonic acid metabolism in cultured alveolar macrophages from normal, atopic, and asthmatic subjects. AM, LTB4, PGD2, PGE2, TXB2
720  1988 Arachidonic acid metabolism in HEL/30 murine epidermal cell line. 15-HETE, ETYA, LTB4, TPA
721  1988 Arachidonic acid metabolism in polymorphonuclear cells in headaches. A methodologic study. CPH, PMNs, PS
722  1988 Arachidonic acid metabolism of cultured peritoneal rat macrophages and its manipulation by nonsteroidal antiinflammatory agents. HETE, HHT, NDGA, PG, TPA, TXB2
723  1988 Arachidonic acid metabolites and their circadian rhythm in patients with allergic bronchial asthma. PEF
724  1988 Arachidonic acid reversal of phenytoin-induced neural tube and craniofacial defects in vitro in mice. DPH
725  1988 Biosynthesis of 20,20,20-trifluoroleukotriene B4 from 20,20,20-trifluoroarachidonic acid: a metabolically stable analog of leukotriene B4 and its application to a study of stimulation of leukotriene B4 synthesis by immunoglobulin G1,2. ---
726  1988 Bovine placental prostaglandin synthesis: principal cell synthesis as modulated by the binucleate cell. BNC, PGE2, PGEs, PGF2 alpha, PGFs, PGs
727  1988 Butter-enriched diets reduce arterial prostacyclin production in rats. EDRF, EPA
728  1988 Changes in human plasma essential fatty acid levels as a result of administration of linoleic acid and gamma-linolenic acid. DGLA, GLA, LA
729  1988 Characterization of arachidonic acid metabolism in Watanabe heritable hyperlipidemic (WHHL) and New Zealand white (NZW) rabbit aortas. HETEs, NZW, PGs, WHHL
730  1988 Characterization of the low mol. wt zinc-binding ligand from rat small intestine by comparison to the organic zinc-binding ligands. AT, CA, L-His, LMW-ZBL, PA, PG
731  1988 Cicletanine and eicosanoids in cultured vascular smooth muscle cells. ---
732  1988 Combined arachidonic acid and ADP platelet inhibition maximizes patency of small-diameter vascular grafts. ADP, TC, TP, TR, TX
733  1988 Cyclooxygenase products from endogenous arachidonic acid in isolated dog and rabbit lungs. PG, TXA2
734  1988 Decreased platelet number and function and increased fibrinolysis contribute to postoperative bleeding in cardiopulmonary bypass patients. AP, ATIII, CP, fPA, PLG
735  1988 Delta 9-tetrahydrocannabinol increases arachidonic acid levels in guinea pig cerebral cortex slices. THC
736  1988 Desensitization of pituitary gonadotropes by mediators of LH release. GnRH, LH, TPA
737  1988 Dietary immunoregulation of transfusion-induced immunosuppression. FO, LA, OA
738  1988 Differential effects of 15-HPETE on arachidonic acid metabolism in collagen-stimulated human platelets. 15-HPETE
739  1988 Docosahexaenoic acid and other dietary polyunsaturated fatty acids suppress leukotriene synthesis by mouse peritoneal macrophages. DHA, EPA, LNA, PUFA
740  1988 Dual effect of the phorbol ester TPA on arachidonic acid release from HeLa cells. PLA2, TPA
741  1988 Dual stimulation of phospholipase activity in human monocytes. Role of calcium-dependent and calcium-independent pathways in arachidonic acid release and eicosanoid formation. CO, HETE, LO
742  1988 Effect of dietary fish oil supplementation on eicosanoid production by rat renal allografts. BT, FO, PG, TX
743  1988 Effect of glucocorticoids, monokines and growth factors on the spontaneously developing responses of the rabbit isolated aorta to des-Arg9-bradykinin. Des-Arg9-BK, DSP, IL-1, IL-2, TGF-beta, TNF
744  1988 Effect of phorbolmyristate acetate on fatty acid uptake and distribution in human promyelocytic leukemia (HL-60) cells in vitro. LA, PMA
745  1988 Effect of polyunsaturated fatty acids of the n-3 and n-6 series on lipid composition and eicosanoid synthesis of platelets and aorta and on immunological induction of atherosclerosis in rabbits. EPA, PUFA
746  1988 Effects of a specific inhibitor of the 5-lipoxygenase pathway on mediator release from human basophils and mast cells. 5-HETE, LT
747  1988 Effects of alpha-tocopherol, its carboxylic acid chromane compound and two novel antioxidant isoflavanones on prostaglandin H synthase activity and autodeactivation. ---
748  1988 Effects of an extract of feverfew (Tanacetum parthenium) on arachidonic acid metabolism in human blood platelets. FE, PL, SH
749  1988 Effects of certain herbal medicines on the biotransformation of arachidonic acid: a new pharmacological testing method using serum. ---
750  1988 Effects of changes in intracellular pH induced by platelet storage and treatment with monovalent cation ionophores on platelet functions. ---
751  1988 Effects of experimental diabetes on spontaneous contractions, on the output of prostaglandins and on the metabolism of labelled arachidonic acid, in uteri isolated from ovariectomized rats. Influences of estradiol. Eo, IDT, PGs
752  1988 Effects of latamoxef on in vitro and ex vivo thromboxane A2 generation in human platelets. LMOX, TX
753  1988 Effects of phospholipase A2 and its hydrolytic products on alveolar epithelial permeability and elastase-induced emphysema. alpha 1 PI, lysoPC, PA, PLA2, PPE, PS
754  1988 Effects of trapidil and trapidil derivatives on arachidonic acid and prostaglandin endoperoxide analogue U 46619-induced blood pressure changes in rats. ASA, TD, TXA2
755  1988 Effects of various drugs on superoxide generation, arachidonic acid release and phospholipase A2 in polymorphonuclear leukocytes. fMLP, PMNs
756  1988 Eicosanoid synthesis in 7,12-dimethylbenz(a)anthracene-induced mammary carcinomas in Sprague-Dawley rats fed primrose oil, menhaden oil or corn oil diet. CO, DHA, DMBA, EPA, GLA, LA, MO, PO
757  1988 Endothelium-dependent and independent responses to prostaglandin H2 and arachidonic acid in isolated dog cerebral arteries. PG
758  1988 Evaluation of prostaglandins as mediators of tubuloglomerular feedback. SFP, TGF, TXA2
759  1988 Evidence that the histamine sensitivity and responsiveness of guinea-pig isolated trachea are modulated by epithelial prostaglandin E2 production. PGE2
760  1988 Exogenous arachidonic acid promotes insulin release from intact or permeabilized rat islets by dual mechanisms. Putative activation of Ca2+ mobilization and protein kinase C. ---
761  1988 Experimental pharmacologic cerebroprotection. APL, DEF, NS, NX, SOD
762  1988 Extract of a spice--omum (Trachyspermum ammi)-shows antiaggregatory effects and alters arachidonic acid metabolism in human platelets. ---
763  1988 Failure of non-selective inhibition of arachidonic acid metabolism to ameliorate hyperoxic lung injury. ---
764  1988 Glucocorticoids stimulate prostaglandin synthesis in human amnion cells by a receptor-mediated mechanism. PGE2
765  1988 Gonadal steroid effects on LH response to arachidonic acid and protein kinase C. LH, PKC, TPA
766  1988 Gonadotropic regulation of prostaglandin production by ovarian follicular cells of the pig. GC, GC-108, TC-108, hCG, LH, PMSG, TC
767  1988 Guanine nucleotides inhibit agonist-stimulated arachidonic acid release in both intact and saponin-permeabilized human platelets. ---
768  1988 Health effects and metabolism of dietary eicosapentaenoic acid. EPA
769  1988 High-performance-liquid-chromatographic analysis of radiolabelled prostaglandins and fatty acids with the radial compression column. ---
770  1988 Hydrogen peroxide inhibits alveolar macrophage 5-lipoxygenase metabolism in association with depletion of ATP. 5-HETE, RIAs, RP-HPLC
771  1988 Hydrogen-peroxide-induced arachidonic acid metabolism in the rat alveolar macrophage. AM, PG, TX
772  1988 Hydroperoxide-induced chemiluminescence in rabbit lungs: role of arachidonic acid enzymes. PG, t-BuOOH, TXB2
773  1988 In vitro effect of trichosanic acid, a major component of Trichosanthes japonica on platelet aggregation and arachidonic acid metabolism in human platelets. 12-HETE, HHT, LNA, TCA, TXB2
774  1988 Increased production of prostacyclin (PGI2) by vascular intimal smooth muscle cells from atherosclerotic rabbit aorta. SMC
775  1988 Increased urinary excretion of thromboxane B2 and 2,3-dinor-TxB2 in cyclosporin A nephrotoxicity. CsA, GFR, IPK, iTxB2, PRP
776  1988 Influence of OKY-1581 on responses to arachidonic acid in the feline pulmonary vascular bed. ---
777  1988 Influence of polymorphonuclear leukocytes on the metabolism of arachidonate in human platelets. 12-HETE, PMNL, TXB2
778  1988 Influence of the antianginal drug trapidil and its derivative AR 12463 on arachidonic acid liberation and thromboxane formation in thrombin-stimulated platelets. TPs, TX
779  1988 Inhibition of arachidonic acid-induced vasogenic brain edema by the non-glucocorticoid 21-aminosteroid U74006F. ---
780  1988 Inhibition of cysteinyl-leukotriene production by azelastine and its biological significance. HPLC, LT, NDGA
781  1988 Inhibition of platelet aggregation by manoalide: preliminary results. MND
782  1988 Inhibitory effect of exogenous arachidonic acid on alveolar macrophage 5-lipoxygenase metabolism. Role of ATP depletion. LT
783  1988 Inhibitory effect of glycyrrhetinic acid derivatives on arachidonic acid-induced mouse ear oedema. ---
784  1988 Inhibitory effects of trimetazidine dihydrochloride on aggregation, serotonin release and malondialdehyde production in rabbit platelets. MDA, TMZ
785  1988 Intestinal zinc transport: influence of streptozotocin-induced diabetes, insulin and arachidonic acid. ---
786  1988 Investigation of the nutritional state of children in a Congolese village. II. Plasma fatty acid composition. CE, DHLA, LA, PL
787  1988 Lack of effect of fish oil-enriched diet on experimental allergic neuritis in Lewis rats. EAN, EPA, LT
788  1988 Leukotriene B4 production in human atherosclerotic plaques. LT
789  1988 Lipid composition of platelets from patients with atherosclerosis: effect of purified eicosapentaenoic acid ethyl ester administration. Chol, EPA, LDL, PC, PL
790  1988 Lysophosphatidylcholine and the inflammatory action of neutrophils. lysoPC, NAG, PC
791  1988 Mechanism of inhibitory action of tranilast on the release of slow reacting substance of anaphylaxis (SRS-A) in vitro: effect of tranilast on the release of arachidonic acid and its metabolites. PEC, PG, PMC, SRS-A
792  1988 Metabolic fate of arachidonic acid in hepatocytes of continuously endotoxemic rats. ET, PI
793  1988 Metabolism of arachidonic acid through the 5-lipoxygenase pathway in normal human peritoneal macrophages. 5-HETE, LT, PM
794  1988 Methylene blue inhibits the arachidonic acid metabolism in human blood platelets. MB
795  1988 Mobilization of arachidonic acid in collagen-stimulated human platelets. 12-HETE, PC, PE, PGH2, PI, PS
796  1988 Modulation of arteriolar blood flow by inhibitors of arachidonic acid oxidation after thermal injury: possible role for a novel class of vasodilator metabolites. ---
797  1988 Modulation of leucocyte activation in the early phase of the rabbit burn injury. LTB4, PAF, PMN
798  1988 Novel renal arachidonate metabolites. EET, SHRs, TALH
799  1988 Oxidative phenomena are implicated in human T-cell stimulation. PBL, PHA, PMA
800  1988 Phospholipase A2 activation in human neutrophils. Differential actions of diacylglycerols and alkylacylglycerols in priming cells for stimulation by N-formyl-Met-Leu-Phe. 5-HETE, fMLP, LTB4, OAG
801  1988 Phospholipase activation and arachidonic acid release in isolated intestinal epithelial cells. ---
802  1988 Phospholipase C from clostridium perfringens induces human platelet aggregation in plasma. PAF, PLC, PRP, TAC
803  1988 Platelet arachidonic acid metabolism in patients with cardiovascular disorders. COX, HMS, MDA, PG, TX
804  1988 Platelet synthesis of cyclooxygenase and lipoxygenase products in type I and type II diabetes. CO, PGE2, TXA2
805  1988 Polyunsaturated fatty acids of serum lipids in myocardial infarction. CE, GC, MI, NEFA, PGI, PL, TG
806  1988 Possible involvement of lipoxygenase pathway of arachidonic acid in rat pituitary hormone release in vitro. 5HETE, beta-E, LTB4
807  1988 Production of lipoxygenase metabolites of eicosapentaenoic acid by bovine alveolar macrophages in vitro. 5-HEPE, BAMs, HETEs, LTs
808  1988 Prostacyclin and thromboxane formation following chronic exposure to cigarette smoke condensate administered via osmotic pumps in rats. A method for chronic administration of particulates of whole smoke. ---
809  1988 Prostacyclin synthesis by endothelial cells from human umbilical veins: effect of cumulative population doublings. HUVE, PDs
810  1988 Prostaglandin E2 and thromboxane B2 release from human monocytes treated with bacterial lipopolysaccharide. LPS, PGE2, TXB2
811  1988 Prostaglandins, leukotrienes, and other arachidonic acid metabolites in the pathogenesis of otitis media. LTs, MEE, OM, PGs, TT
812  1988 Pulmonary intravascular macrophages metabolize arachidonic acid in vitro. Comparison with alveolar macrophages. HETE, HHT, LT, PG, TX
813  1988 Recognition of acidic phospholipase A2 activity in plasma membranes of resident peritoneal macrophages. PC, PLase
814  1988 Regulation of arachidonic acid-dependent Ca++ influx in human platelets. GP, PG, TXA2
815  1988 Renal cytochrome P-450-related arachidonate metabolism in rabbit aortic coarctation. TALH
816  1988 Role of arachidonic acid in luteinizing hormone-releasing hormone action: stimulation of progesterone production in rat granulosa cells. TPA
817  1988 Selective inhibition of leukotriene C4 synthesis and natural killer activity by ethacrynic acid. CA, ET, FA, GST, LTC4, NA, NK
818  1988 Serum interferon activity in inflammatory bowel disease. Arachidonic acid release and lipoxygenation activated by alpha-class interferon in human neutrophils. 5-HETE, CIBD, IFN, LTB4
819  1988 Source of endogenous arachidonate and 5-lipoxygenase products in human neutrophils stimulated by bradykinin and A23187. 5-HETE, 5-HT, BK, LTB4
820  1988 Stimulation of arachidonic acid metabolism by adherence of alveolar macrophages to a plastic substrate. Modulation by fetal bovine serum. FBS, LTB4, TXB2
821  1988 Stimulus-response coupling in fresh and stored granulocytes. CTX, FMLP, HETE, LTB4, RT, SRC
822  1988 Studies on peroxidation of arachidonic acid in different liposomes below and above phase transition temperature. DPPC, DPPE, MDA, SUV, Tm
823  1988 Sulfidopeptide-leukotrienes are major mediators of arachidonic acid-induced mouse ear edema. LTs, PG
824  1988 The adenylate cyclase of rheumatoid synovial fluid macrophages is more sensitive for dl-5E, 19,14-di dehydro-carbo-prostacyclin, a stable prostacyclin analogue, than for prostaglandin E2. cAMP, PG, TX
825  1988 The alkenylacyl class of ethanolamine phospholipid represents a major form of eicosapentaenoic acid (EPA)-containing phospholipid in the platelets of human subjects consuming a fish oil concentrate. DHA, DPA, EPA, PC, PE
826  1988 The association of in vitro arachidonic acid responsiveness and plasma thromboxane levels with early platelet deposition on the luminal surface of small-diameter grafts. ADP, TSI
827  1988 The dynamics of arachidonic acid liberation and prolactin release: a comparison of thyrotropin-releasing hormone, angiotensin II, and neurotensin stimulation in perifused rat anterior pituitary cells. AII, DA, NT
828  1988 The effect of selected arachidonic acid metabolites on natural killer cell activity. NK, PGE2
829  1988 The infusion of trieicosapentaenoyl-glycerol into humans and the in vivo formation of prostaglandin I3 and thromboxane A3. EPA, PG, TX
830  1988 The measurement of platelet aggregation and ATP-release in mice with liver damage induced by carbon tetrachloride (CCl4) using a whole blood aggregometer. ---
831  1988 The oral gold compound auranofin triggers arachidonate release and cyclooxygenase metabolism in the alveolar macrophage. AF, AMs, LT, PG, TX
832  1988 Transitional changes in arachidonic acid metabolism by bovine embryos at different developmental stages. PGE2, RIA
833  1988 Ultrastructural autoradiographic localization of exogenous arachidonic acid in cultured endothelial and smooth muscle cells. EC, SMC
834  1988 [An analysis of 220 cases of pregnancy termination and induced menstruation by alcoholic extract of Wikstroemia Chamaedaphne]. PG
835  1988 [Increase of the prostacyclin/thromboxane A2 ratio in the plasma of rabbits treated with cicletanine, a new antihypertensive agent]. ---
836  1988 [Possible significance of the lipoxygenase pathway of arachidonic acid metabolism for the pathogenesis of constrictive reactions of lung blood vessels]. LOX, PLP
837  1988 [Selective augmenting effect of oxy-Hb on the contractions of cerebral arteries elicited by various vasoactive substances]. ATII, DAG, HA, IDM, NCDC, OAG, oxyHb, PGF2 alpha, TXA2
838  1989 9,11-Epoxy-9-homo-14-thiaprost-5-enoic acid derivatives: potent thromboxane A2 antagonists. ---
839  1989 Activation of human neutrophil NADPH-oxidase in vitro by the catalytic fragment of protein kinase-C. PKC, PKM
840  1989 Activity of dipyrone on intraplatelet arachidonic acid metabolism: an in vitro study. HPLC, IC, LO, TX
841  1989 Aggregation and/or oxygenated products of arachidonic acid are not required for collagen-induced deacylation of phosphatidylcholine in human platelets. PC
842  1989 Alterations in arachidonic acid metabolism and chemotactic response in polymorphonuclear leukocytes from patients with rheumatoid arthritis. RA
843  1989 Altered membrane fatty acid composition and increased thromboxane A2 generation in platelets from patients with diabetes. DHA, EPA, PC, TXA2
844  1989 Analysis of relaxin release by cultured porcine luteal cells using a reverse hemolytic plaque assay: effects of arachidonic acid, cyclo- and lipooxygenase blockers, phospholipase A2, and melittin. LLCs
845  1989 Arachidonate incorporation into rat aorta lipid fractions and eicosanoid formation. Effect of prolonged prostacyclin production. PL
846  1989 Arachidonic acid affects membrane ionic conductances of GH3 pituitary cells. AP
847  1989 Arachidonic acid as a stimulatory mediator of luteinizing hormone-releasing hormone action in the rat ovary. TPA
848  1989 Arachidonic acid closes gap junction channels in rat lacrimal glands. ---
849  1989 Arachidonic acid evokes inositol phospholipid hydrolysis in astrocytes. IP, PAF
850  1989 Arachidonic acid metabolism by perfused ram testis. 6KF
851  1989 Arachidonic acid mobilization and phosphoinositide turnover by the terminal complement complex, C5b-9, in rat oligodendrocyte x C6 glioma cell hybrids. C9D-HS
852  1989 Arachidonic acid potentiates superoxide anion radical production by murine peritoneal macrophages stimulated with tumor promoters. PEC
853  1989 Arachidonic acid release and prostaglandin biosynthesis in synchronized rat embryo fibroblasts. BSA, FCS, PG
854  1989 Arachidonic acid turnover in peritoneal macrophages is altered in endotoxin-tolerant rats. PC, PE, PI, PS
855  1989 Arachidonic acid-induced bronchomotor responses are partially mediated by release of sensory neuropeptides from capsaicin-sensitive structures. ---
856  1989 Arterial 6-keto-PGF1 alpha and TxB2 release in ex vivo perfused canine vessels: effects of pulserate, pulsatility, altered pressure and flow rate. ---
857  1989 Blockade of ADP-induced Ca2+-signal and platelet aggregation by lipoxygenase inhibitors. LPG, NDGA
858  1989 Bradykinin-induced changes in phosphoinositides, inositol phosphate production and intracellular free calcium in cultured bovine aortic endothelial cells. BAEC, BK, DAG, Ins-1,4,5-P3, PA, PLC
859  1989 Can hemofiltration increase survival time in acute endotoxemia--a porcine shock model. HF
860  1989 Cardiovascular and renal actions of cytochrome P-450 metabolites of arachidonic acid. ---
861  1989 Cells in culture from rabbit medullary thick ascending limb of Henle's loop. ---
862  1989 Cluster headache: incorporation of (1-14C)oleic acid into phosphatidylserine in polymorphonuclear cells. PC, PMNs, PS
863  1989 Cluster headache: increased incorporation of (1-14C)arachidonic acid into phosphatidylserine in polymorphonuclear cells. GPLs, PC, PE, PMNs, PS
864  1989 Comparison of the effect of lipoxygenase metabolites of arachidonic acid and eicosapentaenoic acid on human natural killer cell cytotoxicity. EPA, LO, LTB4, NK
865  1989 Complement C5b-9 complex activates phospholipases in glomerular epithelial cells. DAG, EGTA, GEC, MAC, PA
866  1989 Culture of normal and inflamed rabbit colonic explants. Medium-term prostaglandin profile. PGE2
867  1989 Cyclooxygenase metabolism of endogenous arachidonic acid by cultured human tracheal epithelial cells. HTE
868  1989 Cytochrome P450 dependent arachidonic acid metabolism in hemopoietic cells. HETE's
869  1989 Cytoplasmic pH dependency of Na+/H+ exchange in human platelets activated with thrombin, arachidonic acid, A23187 and TPA. TPA
870  1989 Cytotoxicity of arachidonic acid and of its lipoxygenase metabolite 15-hydroperoxyeicosatetraenoic acid on human breast cancer MCF-7 cells in culture. ---
871  1989 Decrease of polyunsaturated fatty acids and elevation of the oleic/stearic acid ratio in plasma and red blood cell lipids of malnourished cancer patients. CE, LA, PL, PUFA
872  1989 Dietary fatty acids, serum lipids, platelet biochemistry and function. DHA, EPA, LA, PUFA
873  1989 Different pathways initiating arachidonic acid (AA) release/thromboxane (TxA2) formation in human platelets--studies with fluoride and phorbol ester. ---
874  1989 Different patterns of arachidonate metabolism in autologous human blood monocytes and alveolar macrophages. 5-LO, AM, CO, PBM
875  1989 Differential actions of arachidonic acid and melittin on luteinizing hormone release and synthesis. IR, LH
876  1989 Differential activation of human skin cells by platelet activating factor: stimulation of phosphoinositide turnover and arachidonic acid mobilization in keratinocytes but not in fibroblasts. IP, PAF, PC
877  1989 Direct in vivo characterization of delta 5 desaturase activity in humans by deuterium labeling: effect of insulin. DHLA
878  1989 Dysregulation of arachidonic acid release and metabolism by atopic mononuclear cells. CO, HPLC, LO
879  1989 Effect of arachidonic acid on cultured cerebromicrovascular endothelium: permeability, lipid peroxidation and membrane "fluidity". EC, TBA
880  1989 Effect of cytoplasmic pH on platelet activation by arachidonic acid. ---
881  1989 Effect of dietary alpha-linolenate/linoleate balance on collagen-induced platelet aggregation and serotonin release in rats. alpha-LNA, EPA, LA
882  1989 Effect of dietary supplementation with a fish oil concentrate on the alkenylacyl class of ethanolamine phospholipid in human platelets. AdA, EPA, PC, PE
883  1989 Effect of oxygen deprivation on metabolism of arachidonic acid by cultures of rat heart cells. ---
884  1989 Effect of pH on pulmonary vascular tone, reactivity, and arachidonate metabolism. ---
885  1989 Effects of arachidonic acid metabolites and other compounds on the CTLL assay for interleukin-2. IL-2
886  1989 Effects of atrial natriuretic peptide on renal medullary prostaglandin E2 production. ANP, BK, PGE2
887  1989 Effects of AVP and dDAVP on PGE2 synthesis in superfused cortical collecting tubules. ADH, AVP, DDAVP, PGs
888  1989 Effects of dilazep on arachidonic acid metabolism by neutrophils and platelet/neutrophil interactions. 5-HETE, 5S,12S-DiHETE, fMLP, LTB4, PAF
889  1989 Effects of dilazep on cytoplasmic calcium ion concentrations and arachidonic acid metabolism in activated human platelets. ---
890  1989 Effects of inhibitors of phospholipase A2, cyclooxygenase and thromboxane synthetase on paracetamol hepatotoxicity in the rat. PLA2
891  1989 Effects of n-3 polyunsaturated fatty acids on coronary heart disease. CHD, DHA, LA, PC, PE, PL, VF
892  1989 Effects of prostaglandin E3 and eicosapentaenoic acid on rat bone in organ culture. EPA, TGF-alpha
893  1989 Effects of reactive oxygen species on prostacyclin production in perinatal rat lung cells. ---
894  1989 Effects of small concentrations of eicosapentaenoic acid on platelets. EPA
895  1989 Eicosanoid interactions in the canine proximal colon. LTB4, PGE2
896  1989 Eicosanoid metabolism in cholesterol-enriched arterial smooth muscle cells: reduced arachidonate release with concomitant decrease in cyclooxygenase products. CE, cLDL, SMC
897  1989 Eicosanoids in myocardial ischemia. ---
898  1989 Eicosapentaenoic and arachidonic acid: comparison of metabolism and activity in murine epidermal cells. EPA, ODC, TPA
899  1989 Endothelin-induced mobilization of Ca2+ and the possible involvement of platelet activating factor and thromboxane A2. ET, PAF, TXA2, VSMC
900  1989 Enhanced glomerular thromboxane A2 mediates some pathophysiologic effect of platelet-activating factor in rabbit nephrotoxic nephritis: evidence from biochemical measurements and inhibitor trials. 6-keto-PGF1 alpha, NTN, PAF, PGE2, TXA2, TXB2
901  1989 Evidence of GTP-binding protein regulation of phospholipase A2 activity in isolated human platelet membranes. ---
902  1989 Extracellular phospholipase A2 activity in cell free peritoneal lavage fluid from mice with zymosan peritonitis. LTC4, PLA2
903  1989 Extracts from two frequently consumed spices--cumin (Cuminum cyminum) and turmeric (Curcuma longa)--inhibit platelet aggregation and alter eicosanoid biosynthesis in human blood platelets. ---
904  1989 Factors subserving the enhancing effect of progesterone on the output of prostaglandin F2 alpha in uteri from ovariectomized rats. PGs
905  1989 Formation of PGI3 in the rat during dietary fish oil supplementation. EPA
906  1989 Free arachidonic acid source for PGE2 and TXB2 production in guinea pig peritoneal macrophages exposed to insoluble glucan from Streptococcus mutans. PC, PI
907  1989 Functional and metabolic heterogeneity among normal neutrophil subpopulations. fMLP
908  1989 Granulocyte-macrophage colony-stimulating factor primes neutrophils by activating a pertussis toxin-sensitive G protein not associated with phosphatidylinositol turnover. DAG, fMLP, GM-CSF
909  1989 Guanine nucleotides and fluoride enhance carbachol-mediated arachidonic acid release from phosphatidylinositol. Evidence for involvement of GTP-binding protein in phospholipase A2 activation. ---
910  1989 Immunopharmacological analysis of endotoxin-induced uveitis in the rat. EIU
911  1989 Immunoregulation of transfusion-induced immunosuppression with inhibitors of the arachidonic acid metabolism. NDGA, TII
912  1989 Impaired cytoplasmic ionized calcium mobilization in inherited platelet secretion defects. ADP, ATP, PAF, PRP
913  1989 In vitro adsorption losses of arachidonic acid and calcium ionophore A23187. BSA
914  1989 In vitro inhibition of arachidonic acid metabolism by two novel retinoid analogs. HDF, MO
915  1989 In vivo assessment of precursor induced prostaglandin release within the rat gastric lumen. DHGL, GLA, PG
916  1989 In-vitro versus in-vivo activities of new 5-lipoxygenase inhibitors with antiinflammatory activity. CO, LO, ODC, TPA
917  1989 Incorporation of arachidonic acid into lipids of the isolated perfused rat lung. 6-keto-PGF1 alpha, LT, PC, PE, PI
918  1989 Increase of phosphatidylinositol arachidonic acid incorporation induced by mepacrine. BK, Mp, PC, PE, PI
919  1989 Increased erythrocyte membrane arachidonate and platelet malondialdehyde (MDA) production in psoriasis: normalization after fish-oil. MDA, PUFA
920  1989 Increased incorporation of L-(U-14C)serine into phosphatidylserine in polymorphonuclear cells from cluster headache patients. PMNs, PS
921  1989 Influence of a cytomegalovirus infection on functions and arachidonic acid metabolism of rat peritoneal macrophages. 5-HETE, CL, HHT, LTB4, p.i
922  1989 Influence of highly concentrated n-3 fatty acids on serum lipids and hemostatic variables in survivors of myocardial infarction receiving either oral anticoagulants or matching placebo. DHA, EPA, OAC, TG
923  1989 Inhibition of GSH-dependent PGH2 isomerase in mammary adenocarcinoma cells by allicin. ---
924  1989 Inhibition of neutrophil response by curcumin. STZ, ZAP
925  1989 Inhibition of pulmonary thromboxane A2 synthase activity and airway responses by CGS 13080. ---
926  1989 Inhibitors of arachidonic acid metabolism eliminate the increase in cytosolic free calcium induced by the mitogen concanavalin A in rat thymocytes. Con A
927  1989 Inhibitory action of gliclazide on platelet functions. cAMP, GC, PGI2, TXA2
928  1989 Inhibitory effect of 8-bromo cyclic GMP on an extracellular Ca2+-dependent arachidonic acid liberation in collagen-stimulated rabbit platelets. 8-Br cGMP, TX
929  1989 Inhibitory effects of diclofenac and indomethacin on interleukin-1-induced changes in PGE2 release. A novel effect on free arachidonic acid levels in human synovial cells. IL-1, NSAIDS, PC, PE, PGE2, TG
930  1989 Interleukin-1 potentiates bradykinin- and TNF alpha-induced PGE2 release. CO, PGE2, TNF-alpha
931  1989 Intracellular platelet-activating factor regulates eicosanoid generation in guinea-pig resident peritoneal macrophages. fMLP, PAF
932  1989 Involvement of arachidonic acid metabolites in increases in vascular permeability in experimental dental pulpal inflammation in the rat. 12-HETE, LPS, PG
933  1989 Isolation and effects of some garlic components on platelet aggregation and metabolism of arachidonic acid in human blood platelets. MEE
934  1989 Kallikrein stimulates arachidonic acid release and production of prostaglandins from TEA3A1 endocrine thymic epithelial cells. PGE2, TXB2
935  1989 Leukotriene D4 and platelet-activating factor-acether antagonists on allergic and arachidonic acid-induced reactions in guinea pig airways. LT, OA, PAF
936  1989 Levuglandin E2 crosslinks proteins. LGE2
937  1989 Mast cell mediators stimulate synthesis of arachidonic acid metabolites in macrophages. HETE, LT
938  1989 Mechanism of arachidonic acid liberation in platelet-activating factor-stimulated human polymorphonuclear neutrophils. PAF
939  1989 Mechanism of membrane phospholipid degradation in ischemic-reperfused rat hearts. LPC, PC
940  1989 Mechanism of the activation of arachidonic acid release by oxysterols in NRK 49F cells: role of calcium. FCS, PG
941  1989 Mechanisms of vascular graft thrombosis: role of altered canine platelet sensitivity to thromboxane. TXB2
942  1989 Metabolism of gamma-linolenic acid in primary cultures of rat hepatocytes and in Hep G2 cells. DGLA, GLA, LLA
943  1989 Metabolism of unsaturated fatty acids by RBL-1 5-lipoxygenase: influence of substrate solubility and product inactivation. EPA
944  1989 Modulation of phospholipase A2 activity in human fibroblasts. BK, HSF, PGE2, PLA2, rIL-1 alpha
945  1989 Multiple defects in arachidonate metabolism in alveolar macrophages from young asymptomatic smokers. AMs, PBMs
946  1989 Muscarinic stimulation of prostanoid synthesis by the isolated rat trachea: calcium dependency and effect of cortisol and cigarette smoke. DMPP
947  1989 On possible different mechanisms subserving the release of arachidonic and di-homo-gamma-linolenic acids for the formation of monoenoic and bisenoic prostaglandins in uteri from ovariectomized rats. 4-PEA, DGLA, NLs, PC, PGs, PI, PLs, TG
948  1989 Ovine trophoblast protein-1 and human interferon alpha reduce prostaglandin synthesis by ovine endometrial cells. IFN, oTP-1, PG
949  1989 Oxidant-mediated activation of phospholipase A2 in pulmonary endothelium. HTP, t-BuOOH
950  1989 Participation of arachidonic acid metabolism in gonadotropin-releasing hormone stimulation of goldfish gonadotropin release. GnRH, NDGA
951  1989 PGE2 concentrations in renal venous plasma and renal lymph during basal and stimulated conditions in the dog. ---
952  1989 Phase I study of Y-20811, a new long-acting thromboxane synthetase inhibitor by intravenous administration. ADP, AUC, PG, TX, Vss
953  1989 Phospholipase activation and arachidonic acid release in cultured intestinal epithelial cells (INT 407). PMA
954  1989 Phospholipid metabolism in polymorphonuclear leukocytes from rheumatoid arthritis patients: effects of non-steroidal anti-inflammatory agents and clotrimazole. MRAI, NSAIA, PLA2, PMNL, RA
955  1989 Platelet aggregability in sleep-related stroke. AOS, SOS
956  1989 Platelet hypersensitivity induced by 1-chloro-2, 4-dinitrobenzene, hydroperoxides and inhibition of lipoxygenase. ---
957  1989 Potent antiplatelet effects of cyclic clofibric acid (CPIB) analogs on human platelets. AGG, CHCCA, PCCA, PG, SEC, TXA2
958  1989 Primary role of calcium ions in arachidonic acid release from rat platelet membranes. Comparison with human platelet membranes. ---
959  1989 Prostacyclin and thromboxane production by autogenous femoral veins grafted into the arterial circulation of the dog. ---
960  1989 Prostaglandin E1 infusion fails to prevent hyperoxic lung injury in adult rabbits. BAL, PGE1, PGI2, PMN
961  1989 Prostaglandin E2 inhibits and indomethacin and aspirin enhance, A23187-stimulated leukotriene B4 synthesis by rat peritoneal macrophages. db-cyclic AMP, LTB4, PGE2, TXB2
962  1989 Prostaglandin E2 production is synergistically increased in cultured human glomerular mesangial cells by combinations of IL-1 and tumor necrosis factor-alpha 1. HMC
963  1989 Prostaglandins and hypertension. PG
964  1989 Prostaglandins in human brain tumors. ---
965  1989 Prostanoid release from ex vivo perfused canine arteries and veins: effects of prolonged perfusion, intermittent perfusion, as well as exposure to exogenous arachidonic acid, thrombin and bradykinin. ---
966  1989 Protection of the rat gastric mucosa against aspirin injury by arachidonic acid: a dietary prostaglandin precursor fatty acid. PL
967  1989 Protective effect of SK&F 86002, a novel dual inhibitor of arachidonic acid metabolism, in murine models of endotoxin shock: inhibition of tumor necrosis factor as a possible mechanism of action. D-gal, LPS, TNF
968  1989 Reduced sensitivity of human platelets to PAF-acether following ticlopidine intake. ADP
969  1989 Regulation of prostaglandin synthesis by protein kinase C in mouse peritoneal macrophages. PGs, PKC, TPA
970  1989 Release of vasoactive intestinal peptide in mouse cerebral cortex: evidence for a role of arachidonic acid metabolites. 4-AP, PLA2, TTX, VIP
971  1989 Renal vascular responses and eicosanoid release in diabetic rats. AVP, STZ
972  1989 Response of thromboxane B2, malondialdehyde and platelet sensitivity to 3 weeks low-dose aspirin (ASA) in healthy volunteers. MDA, PGI2, TXB2
973  1989 Role of glutathione and glutathione peroxidase in human platelet arachidonic acid metabolism. CDNB, GSH-Px
974  1989 Role of prostaglandin I2 and thromboxane A2 in the regulation of blood pressure. SHRs, TX, WKY
975  1989 Selective activation of the gamma-subspecies of protein kinase C from bovine cerebellum by arachidonic acid and its lipoxygenase metabolites. PKC
976  1989 Significance of myocardial eicosanoid production. ---
977  1989 Stimulation of arachidonic acid metabolism in silica-exposed alveolar macrophages. 5-HETE, BAM, LDH, LTB4
978  1989 Stimulation of heart contractility by supernatants from lectin-activated lymphocytes. Role of IL-2. IL-2
979  1989 Stimulation of prostaglandin synthesis by cholecystokinin in primary culture cells of bovine gallbladder muscle. CCK
980  1989 Systemic interleukin I administration suppresses arachidonic acid-induced ear oedema in the mouse. IL-1 beta
981  1989 The effect of shear stress on the uptake and metabolism of arachidonic acid by human endothelial cells. ---
982  1989 The influence of glutathione depleting agents on human platelet function. CDNB, NEM
983  1989 The metabolism of arachidonic and eicosapentaenoic acids in human neutrophils stimulated by A23187 and FMLP. EPA
984  1989 The pharmacology of arachidonic acid-induced rat PMN leukocyte infiltration. MPO
985  1989 The phospholipid and fatty acid compositions of seal platelets: a comparison with human platelets. EPA, PC, PE, PI, PS
986  1989 The role of arachidonic acid metabolite PGE2 on T cell proliferative response. IFN-gamma, LPS, MO, PBL, PGE2, PHA
987  1989 The role of extracellular Ca2+ and Na+ in paf-acether-induced human platelet activation. paf, TX
988  1989 Treatment with tin prevents the development of hypertension in spontaneously hypertensive rats. BP, SHRs, WKYs
989  1989 Turnover of eicosanoid precursor fatty acids among phospholipid classes and subclasses of cultured human umbilical vein endothelial cells. alkyl-PC, diacyl PC, EPA, EPFAs, ETA, PC, plasmalogen PE
990  1989 [Action of adaptogens: cucurbitacin R diglucoside as a stimulator of arachidonic acid metabolism in the rat adrenal gland]. CRD
991  1989 [Antiplatelet effects of combination therapy with low-dose aspirin and ticlopidine in cerebral ischemia]. 6keto PGF1 alpha, ADP, PA, PAF, PF4, TXB2
992  1989 [Comparative studies on steroidogenesis and prostaglandins production by luteal cells in newly formed corpora lutea and early pregnancy]. CL, PGs
993  1989 [Effect of a new thromboxane A2 antagonist, S-145, on platelet aggregation]. p.o
994  1989 [Effect of Actinomyces viscosus on the production of prostaglandin E2 and thromboxane B2 in macrophages]. A. viscosus, PG, TX
995  1989 [Effect of dauricine on rat and human platelet aggregation and metabolism of arachidonic acid in washed rat platelets]. ADR, Dau
996  1989 [Effect of dazoxiben on cerebrovascular resistance in rabbits]. CBF, CVR
997  1989 [Effect of diglyceride on phospholipase A2 activities in plasma membrane of guinea pig peritoneal macrophases]. PI
998  1989 [Effects of anisodamine on the metabolism of arachidonic acid by washed rat platelets]. 12-HETE, HHT
999  1989 [Effects of imazodan and dazoxiben on cAMP levels and PGI2 production in cultured bovine aortic endothelial cells]. PDE III
1000  1989 [Effects of tetrandrine on rabbit platelet aggregation, thromboxane A2 generation and calmodulin activity]. PRP, Tet, TXA2
1001  1989 [Inhibition of release of prostaglandins and leukotrienes from calcimycin-induced mouse peritoneal macrophages and bovine aorta endothelial cells by anisodamine]. Ani
1002  1989 [The effect of ethanol on the metabolism of arachidonic acid (AA) of peritoneal macrophages of mice]. ---
1003  1989 [The effect of the antiarrhythmic, prajmalium bitartrate, on human thrombocyte function]. ADP, PAF
1004  1990 1-naphthyl N-methyl carbamate effect on intra- and extracellular concentrations of arachidonic acid metabolites, and on the chemiluminescence generation by mouse peritoneal macrophages. 5-HETE, CL, CO, LO, OZ, PGs, TPA
1005  1990 14, 15-Epoxyeicosatrienoic acid promotes endothelial cell dependent adhesion of human monocytic tumor U937 cells. EC
1006  1990 5,6-epoxyeicosatrienoic acid, a novel arachidonate metabolite. Mechanism of vasoactivity in the rat. 5,6-EET
1007  1990 5-Hydroxytryptamine and the metabolism of arachidonic acid by the lipoxygenase and cyclooxygenase of washed human platelets. 12-HETE, 5-HT, CO, TXB2
1008  1990 Age-dependent effect of ozone on pulmonary eicosanoid metabolism in rabbits and rats. PGE2, PGF2 alpha
1009  1990 Alterations in the pattern of arachidonate metabolism accompany rat macrophage differentiation in the lung. 5-LO, CO, IM, PM
1010  1990 Alterations in transfer and lipid distribution of arachidonic acid in placentas of diabetic pregnancies. IDDM
1011  1990 Arachidonate lipoxygenase inhibitors in guinea-pig isolated trachea. Effects on contractions to antigen and various agonists. LT
1012  1990 Arachidonate metabolism increases as rat alveolar type II cells differentiate in vitro. ---
1013  1990 Arachidonic acid metabolism by dioxin-induced cytochrome P-450: a new hypothesis on the role of P-450 in dioxin toxicity. ---
1014  1990 Arachidonic acid metabolism in heat-shock treated human leucocytes. HSP, LMB
1015  1990 Arachidonic acid metabolism in neutrophil granulocytes obtained from synovial fluid in rheumatoid arthritis. 5-HETE, LTB4, RA
1016  1990 Arachidonic acid metabolism in normal human alveolar macrophages: stimulus specificity for mediator release and phospholipid metabolism, and pharmacologic modulation in vitro and in vivo. 5-HETE, LTB4, PMA, TXB2
1017  1990 Arachidonic acid metabolism varies with the state of differentiation in density gradient-separated mouse epidermal cells. HETE, PG
1018  1990 Arachidonic acid metabolites alter G protein-mediated signal transduction in heart. Effects on muscarinic K+ channels. ACh, ACh, ACh, ACh, ACh, GTP gamma S, INDO, mAChR, NDGA
1019  1990 Arachidonic acid modulates hippocampal calcium current via protein kinase C and oxygen radicals. PKC
1020  1990 Arachidonic acid release from cultured human amnion cells: the effect of dexamethasone. PG
1021  1990 Arachidonic acid stimulates phosphoinositide metabolism and catecholamine release from bovine adrenal chromaffin cells. ---
1022  1990 Arachidonic acid stimulates steroidogenesis in goldfish preovulatory ovarian follicles. hCG
1023  1990 Arginine vasotocin-induced prostaglandin synthesis in vitro by the reproductive tract of the viviparous lizard Sceloporus jarrovi. AVT, PGs
1024  1990 ATP-evoked arachidonic acid mobilization in astrocytes is via a P2Y-purinergic receptor. ---
1025  1990 Biochemical and functional abnormalities in hypercholesterolemic rabbit platelets. HC, PC, PI, PRP
1026  1990 Ca2(+)-dependence of arachidonic acid redistribution among phospholipids of cultured mouse keratinocytes. DAG, PtdCho, PtdEtn, PtdIns, PtdSer
1027  1990 Cardiac chemical reflex control of preload in conscious dogs. EDD, EDP, LV
1028  1990 Cellular and biochemical characterization of the anti-inflammatory effects of DuP 654 in the arachidonic acid murine skin inflammation model. PMN
1029  1990 Chemiluminescence response and arachidonic acid metabolism of macrophages induced by gamma-hexachlorocyclohexane (lindane). CL, gamma-HCCH, PGs-LTs
1030  1990 Chloroquine inhibition of cholera toxin. cAMP, CT, PGs, PLA2, PLC
1031  1990 Complex effects of in vitro hyperoxia on alveolar macrophage arachidonic acid metabolism. AM, LT, PG
1032  1990 Concentration-activity profile of the modulation of cyclooxygenase product formation by reduced glutathione in microsomal fractions from the goat lung. PGH2
1033  1990 Constant turnover of arachidonic acid and inhibition of a potassium current in Aplysia giant neurons. IR
1034  1990 Cortical spreading depression is associated with arachidonic acid accumulation and preservation of energy charge. CSD, DC, PCr
1035  1990 Covalent binding of arachidonic acid metabolites to human platelet proteins. Identification of prostaglandin H synthase as one of the modified substrates. PG
1036  1990 Cyclooxygenase and lipoxygenase metabolite synthesis by polymorphonuclear neutrophils: in vitro effect of dipyrone. CO, LO, LTC4, PGE2, PMN, TXA2
1037  1990 Cytochrome P-450 arachidonate metabolites in rat kidney: characterization and hemodynamic responses. 19- and 20-OHAA, EETs, GFR
1038  1990 Cytokine- and calcium ionophore A23187-mediated arachidonic acid metabolism in neutrophils. GM-CSF, TNF
1039  1990 Cytokine-stimulation of prostaglandin synthesis from endogenous and exogenous arachidonic acids in polymorphonuclear leukocytes involving activation and new synthesis of cyclooxygenase. ASA, CHX, COX, CSF, GM, hr, PGE2, PMNL
1040  1990 Decrease in cyclosporin-mediated prostacyclin production in renal versus carotid arteries: a mechanism for cyclosporin-induced hypertension. CA, JV, RA
1041  1990 Detergents, dimeric G beta gamma, and eicosanoid pathways to muscarinic atrial K+ channels. CHAPS
1042  1990 Dietary n-3 polyunsaturated fatty acids and amelioration of cardiovascular disease: possible mechanisms. DHA, EPA, LTB4, n-3 PUFAs, PGI3, TGs
1043  1990 Dietary protein influences polyunsaturated fatty acid patterns of rat tissue lipids. CAS, LA, PC, SOY
1044  1990 Diets rich in n-9, n-6 and n-3 fatty acids differentially affect the generation of inositol phosphates and of thromboxane by stimulated platelets, in the rabbit. DHA, EPA, LA, PRP, TXB2
1045  1990 Differential changes in lipid metabolism of myeloid and lymphoid cell lines induced by treatment with 12-O-tetradecanoylphorbol-13-acetate (TPA). NL, PC, PL, TAG, TPA
1046  1990 Differential dependence on protein kinase C of arachidonic acid metabolism stimulated by hydrogen peroxide and by zymosan in the alveolar macrophage. PKC
1047  1990 Differential regulation of 5-lipoxygenase and cyclo-oxygenase pathways of arachidonate metabolism in rat peritoneal leukocytes. fMLP, LTB4, PMA, TXB2
1048  1990 Dilation of cerebral arterioles by cytochrome P-450 metabolites of arachidonic acid. 5,6-EET, PG
1049  1990 Diminished protein kinase C-activated arachidonate metabolism accompanies rat macrophage differentiation in the lung. AM, PKC, PM
1050  1990 Direct inhibition of smooth muscle myosin light chain kinase by arachidonic acid in a purified system. SMLC, SMLCK
1051  1990 Disparate effects of the prostaglandin synthesis inhibitors, meclofenamate, and flurbiprofen on monkey luteal tissue in vitro. dbcAMP, Flur, MEC, PG
1052  1990 Effect of adenine nucleotides on cyclooxygenase and lipoxygenase enzyme products of arachidonic acid in human platelets. 12-HETE
1053  1990 Effect of arachidonic acid on the inner ear blood flow measured with a laser Doppler flowmeter. PGE2, STA2
1054  1990 Effect of dietary oils on the production of n-3 and n-6 metabolites of leukocyte 5-lipoxygenase in five rat strains. EPA, LTB4
1055  1990 Effect of fish oil and safflower oil in common Japanese diet on human plasma fatty acid composition. DHA, EPA
1056  1990 Effect of fish oil n-3 fatty acids on cerebral microcirculation. CSF, PGE2
1057  1990 Effect of in vivo coal dust exposure on arachidonic acid metabolism in the rat alveolar macrophage. AM, LTB4, PGE2, TXA2
1058  1990 Effect of prostaglandin, leukotriene, and arachidonic acid on experimental otitis media with effusion in chinchillas. LTs, OME, PGs
1059  1990 Effects of acrolein on human platelet aggregation. TXA2
1060  1990 Effects of arachidonic acid and prostaglandin F2 alpha in isolated rat lungs. PVR
1061  1990 Effects of arachidonic acid in the rabbit pulmonary and systemic vascular beds in vivo. Ppa
1062  1990 Effects of arachidonic acid on the gap junctions of neonatal rat heart cells. ---
1063  1990 Effects of calcium loading and impaired energy production on metabolic and ultrastructural features of cell injury in cultured neonatal rat cardiac myocytes. IAA
1064  1990 Effects of nimodipine on platelet aggregation and the activity of enzymes in arachidonic acid metabolism. ---
1065  1990 Effects of oxidized low density lipoproteins on arachidonic acid metabolism in smooth muscle cells. BHT, HPLC, RIA, SMC, TBAR, VLDL
1066  1990 Effects of oxysterols on arachidonic acid metabolism and prostacyclin synthesis in bovine aortic smooth muscle cells in culture. ---
1067  1990 Effects of ozone on cyclooxygenase metabolites in the baboon tracheobronchial tree. BAL, PG, ppm, TX
1068  1990 Effects of plasma on PGI2 release from prolonged perfused canine veins. HBSS, PPP
1069  1990 Eicosanoid production and transfer in the placenta of the diabetic pregnancy. 6KPGF1a, HETEs, HPLC, IDDM, TX
1070  1990 Eicosanoids in rat brain during ischemia and reperfusion--correlation to DC depolarization. PG, TX
1071  1990 Endogenous AA metabolites and their possible role in tracheal smooth muscle tone in guinea pigs. ---
1072  1990 Epoxygenase products of arachidonic acid are endogenous constituents of the hypothalamus involved in D2 receptor-mediated, dopamine-induced release of somatostatin. DA, EETs, GC, ME, MS
1073  1990 Evaluation of Tenidap (CP-66,248) on human neutrophil arachidonic acid metabolism, chemotactic potential and clinical efficacy in the treatment of rheumatoid arthritis. LTB4, RA
1074  1990 Evidence for 5-lipoxygenase activity in human B cell lines. A possible role for arachidonic acid metabolites during B cell signal transduction. 5-HETE, 5-HL
1075  1990 Evidence for coupling of different receptors for gonadotropin-releasing hormone to phospholipases C and A2 in cultured rat luteal cells. GnRH, IPs, PGF2 alpha
1076  1990 Exogenous arachidonic acid metabolism in platelets from psoriatic patients. ---
1077  1990 Free radical generation in human leukocytes by CIS-unsaturated fatty acids is a calmodulin dependent process. fMLP, GLA, LPS, PMA
1078  1990 Functional consequences of phospholipase A2 activation in human monocytes. Con A, HETE'S, LO, LPS, LT's, PLA2, STZ
1079  1990 Generation of lipoxygenase metabolites of arachidonic acid by monolayer cultures of tracheal epithelial cells and intact tracheal segments from rabbits. HETE, LT, TE
1080  1990 Glucocorticoids fail to inhibit arachidonic acid metabolism stimulated by hydrogen peroxide in the alveolar macrophage. AM, TX
1081  1990 Guinea pig alveolar eosinophils and macrophages produce leukotriene B4 but no peptido-leukotriene. HHT, LT
1082  1990 Hemorheologic effects of Meclomen including effect in malignant melanoma. ADP
1083  1990 Histamine-stimulated and GTP-binding proteins-mediated phospholipase A2 activation in rabbit platelets. G proteins, PMA
1084  1990 In vitro goldfish growth hormone responses to gonadotropin-releasing hormone: possible roles of extracellular calcium and arachidonic acid metabolism? GH, NDGA
1085  1990 In vitro prostaglandin H synthase- and monooxygenase-mediated binding of aflatoxin B1 to DNA in guinea-pig tissue microsomes. AFB1, PHS
1086  1990 In vitro study of docosahexaenoic acid incorporation into phosphatidylcholine by enzymes of rat heart. DHA, PC
1087  1990 Induction of endogenous arachidonic acid metabolism in human neutrophils with snake venom phospholipase A2, immune complexes, and A23187. LTB4, PLA2
1088  1990 Influence of dietary fish on eicosanoid metabolism in man. TA
1089  1990 Influence of extracellular calcium on the metabolism of arachidonic acid in alveolar macrophages. CO, LO, PLA2, PMA
1090  1990 Inhibition of arachidonic acid release by nordihydroguaiaretic acid and its antioxidant action in rat alveolar macrophages and Chinese hamster lung fibroblasts. LOOH, NDGA, t-BOOH
1091  1990 Inhibition of human platelet activation by polymorphonuclear leukocytes. ATP, PMNs
1092  1990 Inhibition of human platelet aggregation and thromboxane-B2 production by melatonin: evidence for a diurnal variation. ADP, PRP, TXB2
1093  1990 Inhibition of phospholipase activity in human monocytes by IFN-gamma blocks endogenous prostaglandin E2-dependent collagenase production. ---
1094  1990 Inhibition of prostaglandin and leukotriene generation by the plant alkaloids tetrandrine and berbamine. IL-1, PAF
1095  1990 Inhibitory effects of arachidonic acid on muscarinic current response in single pancreatic acinar cells of rats. 4-BPB, ACh, PLA2
1096  1990 Inositol 1,4,5-trisphosphate- and arachidonic acid-induced calcium mobilization in T and B lymphocytes. ER
1097  1990 Intestinal absorption of arachidonic acid in experimental azotemia. PF, RF
1098  1990 Involvement of a guanine-nucleotide-binding protein-mediated mechanism in the enhancement of arachidonic acid liberation by phorbol 12-myristate 13-acetate and Ca2+ in saponin-permeabilized platelets. ---
1099  1990 Ischemia and reperfusion induced formation of eicosanoids in isolated rat hearts. ---
1100  1990 Key role of diacylglycerol-mediated 12-lipoxygenase product formation in angiotensin II-induced aldosterone synthesis. 12-HETE, AII, DG
1101  1990 Kinetics of phospholipase A2, arachidonic acid, and eicosanoid appearance in mouse zymosan peritonitis. PLA2, UnFA
1102  1990 Lipoxins formation by rat basophilic leukemia (RBL-1) cells. 15-HPETE, GC/MS, LXA4, LXB4, LXs, RP-HPLC
1103  1990 Lipoxygenase inhibitors suppress intracellular calcium rise induced by ionomycin in rat thymocytes. 15-HETE, BPB, LO, NDGA, PLA2
1104  1990 Mechanisms of contracting action of oxyhemoglobin in isolated monkey and dog cerebral arteries. EDRF, PG
1105  1990 Mobilization of arachidonic acid in thrombin-stimulated human platelets. NCDC, PMSF
1106  1990 Modes of inhibitory action of 4 beta-phorbol 12-myristate 13-acetate in thrombin-stimulated arachidonic acid release in intact and permeabilized platelets. PMA
1107  1990 N-6 and N-3 PUFA in liver lipids, thromboxane formation and blood pressure from SHR during diets supplemented with evening primrose, sunflowerseed or fish oil. DHA, EPA, EPO, FO, LA, PC, PE, PUFA, SHR, SO, TG
1108  1990 Non-receptor-mediated refractoriness in prostacyclin production by human endothelial cells in a continuous flow system is delayed by a low-molecular-weight plasma fraction devoid of reducing cofactors for peroxidase-catalysed reactions. HUVECs
1109  1990 Optimization of an assay for studying the effects of agents on cyclooxygenase and lipoxygenase metabolism of arachidonic acid in washed human platelets. ---
1110  1990 Penta- and hexadienoic acid derivatives: a novel series of 5-lipoxygenase inhibitors. 5-LO, CO
1111  1990 Phospholipase A2, an in vivo immunomodulator. ACM, CL, NDGA, PLA2, SOD, TDM
1112  1990 Phospholipase activation and arachidonic acid release in intestinal epithelial cells from patients with Crohn's disease. ---
1113  1990 Phospholipase C from Clostridium perfringens stimulates phospholipase A2-mediated arachidonic acid release in cultured intestinal epithelial cells (INT 407). ---
1114  1990 Possible involvement of arachidonic acid metabolites of cytochrome P450 monooxygenase pathway in vasopressin-stimulated glycogenolysis in isolated rat hepatocytes. CO, EET, ETYA, LO, MO
1115  1990 Possible involvement of different GTP-binding proteins in noradrenaline- and thrombin-stimulated release of arachidonic acid in rabbit platelets. NA
1116  1990 Prevention of stress-induced erosive gastritis by parenteral administration of arachidonic acid. i.p, PG
1117  1990 Production of arachidonic acid metabolites by caprine alveolar macrophages. CAM, HETE, HHT
1118  1990 Production of arachidonic and linoleic acid metabolites by guinea pig tracheal epithelial cells. 5- and 15-HETE, 9- and 13-HODE, HHT, LA, LT
1119  1990 Prostaglandin E2 and F2 alpha in mid-pregnant rat uterus and at parturition. PGE2
1120  1990 Regulation of arachidonic acid release by enzyme(s) of rat brain cortex. PLA2, PLC
1121  1990 Regulation of eicosanoid biosynthesis by phorbol ester in Madin Darby canine kidney cells. BK, COX, MDCK, PGE2, PMA, STP
1122  1990 Regulation of intracellular free arachidonic acid in Aplysia nervous system. ---
1123  1990 Renal vasoconstriction induced by arachidonic acid during burn shock in rats. RBF, TXA2
1124  1990 Retinoids inhibit phospholipase A2 in human synovial fluid and arachidonic acid release from rat peritoneal macrophages. all-trans-RA, PLA2
1125  1990 Role of arachidonic acid in depolarization-induced modulation of ion currents in Aplysia giant neurons. BPB, BSA, cAMP, IR
1126  1990 Role of arachidonic acid or its metabolites in growth-hormone-releasing factor-induced release of somatostatin from the median eminence. GRF, ME
1127  1990 Role of iron on membrane phospholipid breakdown in ischemic-reperfused rat heart. PC
1128  1990 Selenium dependent glutathione peroxidase: a physiological regulatory system for platelet function. GSH-Px, MDA, TXA2, TXB2
1129  1990 Sensitivity of tryptophan and related compounds to oxidation induced by lipid autoperoxidation. Application to human serum low- and high-density lipoproteins. TBARS
1130  1990 Serotonin inhibits ATP-induced mobilization of arachidonic acid but not phosphoinositide turnover in astrocytes. ---
1131  1990 Sex related differences in platelet TxA2 generation. TX
1132  1990 Specific binding of haptoglobin to human neutrophils and its functional consequences. fMLP, PMA
1133  1990 Sphingosine potentiates IL-1-mediated prostaglandin E2 production in human fibroblasts. PKC, PLA2
1134  1990 Stimulation of free radical generation in human leukocytes by various agents including tumor necrosis factor is a calmodulin dependent process. FMP, LPS, PMA, r-TNF-1 alpha
1135  1990 Stimulation of prostaglandin synthesis by hyperoxia in perinatal rat lung cells. PGs
1136  1990 Stimulatory effects of cholera toxin on arachidonic acid metabolism in Chinese hamster ovary cells. CT
1137  1990 Synaptic vesicle-bound phospholipase(s) acting on phosphatidylinositol exhibit(s) high susceptibility to brain ischemia. PhLC, PI, SV
1138  1990 The effect of essential fatty acid deficiency on the adrenergic activation of glycogenolysis in rat hepatocytes. EFA
1139  1990 The effects of different silicas on arachidonic acid metabolism in alveolar macrophages. BAM, HPLC, LDH
1140  1990 The LDL receptor pathway delivers arachidonic acid for eicosanoid formation in cells stimulated by platelet-derived growth factor. LDL, PGs
1141  1990 Thromboxane and prostacyclin levels in fetal rabbit brain and placenta after intrauterine partial ischemic episodes. PG
1142  1990 Thromboxane generation and pulmonary reactivity to arachidonic acid in heart-lung preparation of guinea-pig: modulation by PCO2. HLPs
1143  1990 Ticlopidine prevents renal disease progression in rats with reduced renal mass. TXA2
1144  1990 Ultraviolet radiation suppresses mouse-ear edema induced by topical application of arachidonic acid. PUVA, UV
1145  1990 [Effect of dazoxiben on the metabolism of arachidonic acid in isolated porcine basilar arteries]. LT
1146  1990 [Effects of Codonopsis pilosulae on the synthesis of thromboxane A2 and prostacyclin]. CP
1147  1990 [Effects of ketotifen on rabbit platelet aggregation and platelet activating factor formation from rat neutrophils]. KET, PAF
1148  1990 [Effects of ticlopidine on platelet function at rest and after exercise in patients with previous myocardial infarct. An acute crossover double-blind study]. ---
1149  1990 [Influences of 3,4,5-trihydroxystibene-3-beta-mono-D-glucoside on rabbits' platelet aggregation and thromboxane B2 production in vitro]. ADP, TXB2
1150  1990 [Interaction of CN-100, a novel non-steroidal anti-inflammatory drug, on biopolymers]. IM, PP
1151  1990 [Significance of the PGI2 producing enzyme system in the pathogenesis of pregnancy-induced hypertension]. P.E.S, PIH
1152  1990 [Studies of aggregation using pairs of agonists in platelet concentrates stored for 5 days. Influence of autologous fresh plasma]. PC
1153  1990 [Study on LH release and desensitization by means of a superfusion system with beads attached pituitary cells]. NDGA, OAG, PMA
1154  1990 [The role of arachidonic acid metabolites in the skin]. EPA
1155  1991 5-Acyl-6-aryl-4-nitro-3(2H)pyridazinones and related 4-amino compounds: synthesis and pharmacological evaluation. ADP, ASA, LPS, PAF, PGE2
1156  1991 A new role for the low density lipoprotein receptor. FH, LDL, PDGF, PG, rec-LDL
1157  1991 A novel anti-inflammatory peptide from human lipocortin 5. hrLC5, PGE2, PLA2
1158  1991 A possible mechanism of mitochondrial dysfunction during cerebral ischemia: inhibition of mitochondrial respiration activity by arachidonic acid. ---
1159  1991 A study on the biological behavior of human brain tumors. Part I. Arachidonic acid metabolism and DNA content. ---
1160  1991 Activation of osmolyte efflux from cultured renal papillary epithelial cells. ETYA
1161  1991 Activation of phospholipase D in a rat mast (RBL 2H3) cell line. A possible unifying mechanism for IgE-dependent degranulation and arachidonic acid metabolite release. DAG, PA
1162  1991 ADH-dependent phosphoinositide signalling system and prostaglandin E production in the frog urinary bladder. ADH, DAG, PGE
1163  1991 Amplification of LTB4 generation in AM-PMN cocultures: transcellular 5-lipoxygenase metabolism. AM, HETE, LT, PMN
1164  1991 Arachidonate metabolism in bovine gallbladder mucosa. ---
1165  1991 Arachidonate metabolites and kinins in blood pressure regulation. ---
1166  1991 Arachidonic acid and bradykinin share a common pathway to release neuropeptide from capsaicin-sensitive sensory nerve fibers of the guinea pig heart. CGRP-LI, PG
1167  1991 Arachidonic acid induced increase in intracellular free calcium in guinea-pig hepatocytes. ---
1168  1991 Arachidonic acid is essential for IgG Fc receptor-mediated phagocytosis by human monocytes. EIgG
1169  1991 Arachidonic acid metabolism by bovine placental tissue during the last month of pregnancy. HHT
1170  1991 Arachidonic acid metabolism in human and bovine retina. 12-HETE, LT, PG
1171  1991 Arachidonic acid metabolites and chloride secretion in rabbit distal colonic mucosa. 5-HETE, PGF2 alpha, TXB2
1172  1991 Arachidonic acid metabolites and colchicine in Behcet's disease (BD). BD, LTC4, PGE2, PML
1173  1991 Arachidonic acid metabolites in middle ear effusions of children. MEEs
1174  1991 Arachidonic acid metabolites in pregnant rat uterus. 6-keto-PGF1 alpha, PGE2
1175  1991 Arachidonic Acid-induced Platelet Aggregation ex vivo in Patients with Acute Ischaemic Heart Disease. PRP
1176  1991 Aspirin-induced decline in prostacyclin production in patients with coronary artery disease is due to decreased endoperoxide shift. Analysis of the effects of a combination of aspirin and n-3 fatty acids on the eicosanoid profile. EPA
1177  1991 Attenuation of histamine-induced lymphatic smooth muscle contractility by arachidonic acid. FA
1178  1991 Basal activation of protein kinase C in rat alveolar macrophages: implications for arachidonate metabolism. AM, PKC, PM
1179  1991 Biochemical perturbations of BW 91Y (3-deazaadenosine) on human neutrophil chemotactic potential and lipid metabolism. LF, PC, PE, RA
1180  1991 Both arachidonic acid and 1-oleoyl-2-acetyl glycerol in low magnesium solution induce long-term potentiation in hippocampal CA1 neurons in vitro. DG, EPSPs, LTP, PDBu, PKC, PS
1181  1991 Calcium-dependent biosynthesis of platelet-activating factor by submandibular gland cells. ACh, PAF
1182  1991 Changes of rabbit platelet function on simultaneous administration of ticlopidine hydrochloride and OKY-046. ---
1183  1991 Characterization of phospholipase A2 (PLA2) activity in gerbil brain: enhanced activities of cytosolic, mitochondrial, and microsomal forms after ischemia and reperfusion. PC, PLA2
1184  1991 Characterization of platelet function in cyclic hematopoietic dogs. CH, PAF, PLC, TPA, TXB2
1185  1991 Chick nutritional encephalomalacia and prostanoid formation. L-E, NE, TXB2
1186  1991 Comparison of arachidonate metabolism by alveolar macrophages from bighorn and domestic sheep. AMs, HETEs, LTs, PGs, PMA, TXs
1187  1991 Comparison of responses to angiotensin II of dog mesenteric arteries and veins. AII, EDRF, PG
1188  1991 Contribution of K+ channels to arachidonic acid-induced endothelium-dependent vasodilation in rat isolated perfused mesenteric arteries. ---
1189  1991 Crotoxin, a phospholipase A2 neurotoxin from snake venom, interacts with epithelial mammary cells, is internalized and induces secretion. CA, NDGA, PLA2, PRL
1190  1991 Cytochrome P-450-dependent vasodilation of rat kidney by arachidonic acid. ---
1191  1991 Cytochrome P-450-dependent vasodilator responses to arachidonic acid in the isolated, perfused kidney of the rat. ---
1192  1991 Decrease in platelet reduced glutathione increases lipoxygenase activity and decreases vitamin E. 12-HETE, HPLC, MDA
1193  1991 Delta 9-tetrahydrocannabinol inhibits arachidonic acid acylation of phospholipids and triacylglycerols in guinea pig cerebral cortex slices. THC
1194  1991 Diacylglycerol lipase and the contractile action of epidermal growth factor-urogastrone: evidence for distinct signal pathways in a single strip of gastric smooth muscle. DG lipase, EGF-URO, TGF-alpha
1195  1991 Differential effects of dietary fish oil on myocardial prostaglandin I2 and thromboxane A2 production. PG, PUFA, REF, SF, SSO, TFO, TX
1196  1991 Differential effects of various Ca2+ antagonists. ---
1197  1991 Differential induction of cytochromes P450 and cytochrome P450-dependent arachidonic acid metabolism by 3,4,5,3',4'-pentachlorobiphenyl in the rat and the guinea pig. PenCB
1198  1991 Differentiation-associated expression of prostaglandin H and thromboxane A synthases in monocytoid leukemia cell lines. COX, LOX, PMA, TXA2
1199  1991 Docosahexaenoic acid inhibits PAF and LTD4 stimulated [Ca2+]i-increase in differentiated monocytic U937 cells. EPA, LA, LNA, PUFAs, RA
1200  1991 Dopamine inhibits inositol phosphate production, arachidonic acid formation, and corticosteroid release by frog adrenal gland through a pertussis toxin-sensitive G-protein. DG
1201  1991 Dual inhibition of thromboxane A2 synthesis and thromboxane A2/prostaglandin endoperoxide receptors by ridogrel: anti-thrombotic effect in vivo in rat mesenteric arteries. TXA2
1202  1991 EDRF released from microvascular endothelial cells dilates arterioles in vivo. L-NMMA, MECs
1203  1991 Effect of cytochrome P450 arachidonate metabolites on ion transport in rabbit kidney loop of Henle. ---
1204  1991 Effect of glutathione manipulation on prostaglandin synthesis in renal medullary homogenates. DEM, GSH-MEE, RM
1205  1991 Effect of retinoids and carotenoids on prostaglandin formation by oral squamous carcinoma cells. betaCT, CTX, N-4-HPR, PGs
1206  1991 Effects of chlorpromazine on phosphatidylinositol turnover following thrombin stimulation of human platelets. 1,2-DAG, CPZ, DAG-kinase, PA
1207  1991 Effects of dietary fish oil lipids on allergic and inflammatory diseases. DCHA, EPA
1208  1991 Effects of exercise and ethanol ingestion on platelet thromboxane release in healthy men. ADP
1209  1991 Effects of intravenous and aerosolized arachidonic acid on alveolar epithelial permeability in rabbits. ---
1210  1991 Effects of ozone on lung mechanics and cyclooxygenase metabolites in dogs. 6-keto-PGF1alpha, BAL, Cdyn, PD50, PGE2, PGF2 alpha, TXB2
1211  1991 Effects of Ph CL 28A on eicosanoid synthesis in rat isolated hearts. CDT, CPP
1212  1991 Effects of prostaglandin F2 alpha prostaglandin E2 and arachidonic acid on the induction of oviposition in vivo and in vitro in oviparous lizards. PGF2 alpha
1213  1991 Effects of protein synthesis inhibition on PGE2 production in rabbit colonic explants cultured in vitro. CH, PS
1214  1991 Eicosanoid production and phospholipase A2 secretion by peritoneal macrophages from rats with adjuvant-induced arthritis. LTB4, PGE2, PLA2, RPM
1215  1991 Eicosanoid-dependent and -independent formation of individual [14C]stearoyl-labelled lysophospholipids in collagen-stimulated human platelets. lysoPC, lysoPE, lysoPI, TXA2
1216  1991 Elevation of platelet cyclic AMP level by thromboxane A2/prostaglandin H2 receptor agonists. PKC
1217  1991 Endothelin-1 stimulates the release of arachidonic acid and prostaglandins in rabbit iris sphincter smooth muscle: activation of phospholipase A2. ET-1
1218  1991 Epidermal growth factor modulates intracellular arachidonic acid levels in MA-10 cultured Leydig tumor cells. EGF
1219  1991 Evidence for the possible involvement of protein kinase C in the activation of non-specific phospholipase A2 in human neutrophils. PLA2, PMA
1220  1991 Expression of prostaglandin G/H synthase (cyclooxygenase) during murine fetal thymic development. PGs
1221  1991 Extract and compounds obtained from Mandevilla velutina inhibit arachidonic acid-induced ear oedema in mice, but not rat stomach contraction. CE, MI, PGE2
1222  1991 Fatty acids in human platelets and plasma. Fish oils decrease sensitivity toward N2 microbubbles. ---
1223  1991 Functions of two types of Fc gamma receptor on guinea-pig macrophages in immune complex-induced arachidonic acid release. FcgammaR, OA
1224  1991 Generation of arachidonic acid metabolites from stimulated whole blood in patients with chronic myeloproliferative disorders. ET, MPD, PV
1225  1991 Generation of leukotrienes and hydroxyeicosatetraenoic acids in peritoneal macrophages of tumor-bearing mice. HETEs, LTs
1226  1991 Hydroxynonenal, a component of clastogenic factors? CF, X-XO
1227  1991 Identification of 12(S)-hydroxyeicosatetraenoic acid in the young rat lens. ---
1228  1991 Immunosuppressive mechanisms in protein-calorie malnutrition. MFR, PCM, PGE2
1229  1991 In vitro antiplatelet profiles of the new thromboxane synthetase inhibitor sodium 2-(1-imidazolylmethyl)-4,5-dihydrobenzo[b]thiophene-6-carboxylate. PRP, TX
1230  1991 In vitro effects of picotamide on human platelet aggregation, the release reaction and thromboxane B2 production. ASA, MDA, PE, TXB2
1231  1991 In vitro secretion of prostaglandins from endometrium of postpartum beef cows expected to have short or normal luteal phases. 6-keto-PGF1 alpha, PGE2, PGF
1232  1991 Induction of interleukin-6 release by interleukin-1 in rat anterior pituitary cells in vitro: evidence for an eicosanoid-dependent mechanism. IL-1, PLA2
1233  1991 Induction of vascular injury by Pseudomonas aeruginosa cytotoxin in rabbit lungs is associated with the generation of different leukotrienes and hydroxyeicosatetraenoic acids. HETEs, LT
1234  1991 Influence of chemotherapeutic agents on prostacyclin synthesis. II. Effects of tetracycline and penicillin G on prostacyclin synthesis by the rat thoracic aorta and myometrial tissues. ---
1235  1991 Influence of diethylcarbamazine and mefloquine on PGI2 synthesis by the rat thoracic aorta and myometrial tissues. Mf, PLA2
1236  1991 Influence of quin 2, fura 2 and indo 1 on platelet function and on the measurement of cytosolic free calcium ions. PAF
1237  1991 Ingestion of eicosapentaenoic acid-ethyl ester renders rabbit LDL less susceptible to Cu2(+)-catalyzed-oxidative modification. EPA-E, LDL
1238  1991 Inhibition of depolarisation-induced calcium influx into GH3 cells by arachidonic acid: the involvement of protein kinase C. PDBu, PKC
1239  1991 Inhibition of human platelet aggregation and thromboxane B2 production by melatonin. Correlation with plasma melatonin levels. PRP, TXB2
1240  1991 Inhibition of leukotriene B4 formation in rat peritoneal neutrophils by an ethanolic extract of the gum resin exudate of Boswellia serrata. 5-LOX, PMNL
1241  1991 Inhibitory effect of new PAF antagonists on PAF-induced rabbit platelet aggregation in vitro and ex vivo. ---
1242  1991 Inhibitory effects of licochalcone A isolated from Glycyrrhiza inflata root on inflammatory ear edema and tumour promotion in mice. DMBA, TPA
1243  1991 Interleukins 1 alpha and 6 and tumor necrosis factor-alpha are paracrine inhibitors of human melanocyte proliferation and melanogenesis. IL, NHM, TNF
1244  1991 Involvement of capsaicin-sensitive nerves in the bronchomotor effects of arachidonic acid and melittin: a possible role for lipoxin A4. ---
1245  1991 Isolation of a novel arachidonic acid metabolite 3-hydroxy-5,8,11,14-eicosatetraenoic acid (3-HETE) from the yeast Dipodascopsis uninucleata UOFs-Y128. 3-HETE, EI, HPLC, MS, TLC
1246  1991 Lack of dose response by dietary n-3 fatty acids at a constant ratio of n-3 to n-6 fatty acids in suppressing eicosanoid biosynthesis from arachidonic acid. ---
1247  1991 Lack of involvement of arachidonic acid metabolism in chicken gonadotropin-releasing hormone II (cGnRH-II) stimulation of gonadotropin secretion in dispersed pituitary cells of goldfish, Carassius auratus. Identification of a major difference in salmon GnRH and chicken GnRH-II mechanisms of action. cGnRH-II, cGnRH-II, NDGA
1248  1991 Leukotriene C4 and prostaglandin E2 activities in the serum and cerebrospinal fluid during acute cerebral ischemia. CSF, PGE2
1249  1991 Linoleic acid and dihomogammalinolenic acid inhibit leukotriene B4 formation and stimulate the formation of their 15-lipoxygenase products by human neutrophils in vitro. Evidence of formation of antiinflammatory compounds. 15-HETE, DGLA, LA, LO, LTB4, LTs, PUFA, RP-HPLC
1250  1991 Long-term administration of highly purified eicosapentaenoic acid provides improvement of psoriasis. DHA, EPA, LTB4, LTB5
1251  1991 Long-term feeding of formulas high in linolenic acid and marine oil to very low birth weight infants: phospholipid fatty acids. DHA, PE, RBC
1252  1991 Mechanism of arachidonic acid transport across rabbit distal colonic mucosa. PD
1253  1991 Mechanism of regulation of prostaglandin production by parathyroid hormone, interleukin-1, and cortisol in cultured mouse parietal bones. IL-1, PG, PTH
1254  1991 Melittin stimulates phosphoinositide hydrolysis and placental lactogen release: arachidonic acid as a link between phospholipase A2 and phospholipase C signal-transduction pathways. ---
1255  1991 Novel arachidonate metabolites generated by cytochrome P450-dependent mono-oxygenases. mTALH
1256  1991 Pharmacology of thromboxane A2, prostacyclin and other eicosanoids in the cardiovascular system. ---
1257  1991 Phorbol ester plus calcium ionophore induces release of arachidonic acid from membrane phospholipids of a human B cell line. OLE, PAL, PKC, PMA, STE
1258  1991 Photoreactivation of ultraviolet radiation-induced release of arachidonic acid from marsupial cells. UVR
1259  1991 Platelet-activating factor (PAF) receptor antagonists inhibit arachidonic acid induced platelet aggregation in rabbit whole blood. ADP, PAF
1260  1991 Platelet-activating factor stimulates eicosanoid production in cultured feline tracheal explants. HETE, HPLC, LT, PAF, PG, RIA, TX
1261  1991 Positive inotropic effect of interleukin-2. Role of phospholipases and protein kinase C. BPB, IL-2, NCDC, OAG
1262  1991 Possible implication of arachidonic acid metabolism in the decrease of chemiluminescence production after exposure of murine peritoneal macrophages to diethylnitrosamine and tumour promoter, 12-O-tetradecanoylphorbol-13-acetate. CO, DEN, LTs, PGs, PKC, PLA2, TPA
1263  1991 Production of the polyunsaturated fatty acids arachidonic acid and eicosapentaenoic acid by the fungus Pythium ultimum. EPA, PUFAs
1264  1991 Prostacyclin production in the area of arterial endothelial denudation. ---
1265  1991 Protein kinase C and cyclic AMP modulate thrombin-induced platelet-activating factor synthesis in human endothelial cells. EC, PAF, PKC, PLA2, PMA
1266  1991 Protein kinase C dependent and independent activation of phospholipase A2 under calcium ionophore (A23187) exposure in rabbit pulmonary arterial smooth muscle cells. PKC, PLA2
1267  1991 Protein kinase C regulates MHC-class II expression on endothelial cells. EC, IFN-gamma, PKC, PMA
1268  1991 Regulation of agonist-induced prostaglandin E1 versus prostaglandin E2 production. A mass analysis. DHLA, PGE1, PGE2
1269  1991 Renal cytochrome P-450-dependent metabolism of arachidonic acid in cirrhotic rats. HPLC
1270  1991 Role of corticosterone in modulation of eicosanoid biosynthesis and antiinflammatory activity by 5-lipoxygenase (5-LO) and cyclooxygenase (CO) inhibitors. 5-LO, CO, LO, TXB2
1271  1991 Saturability of esterification pathways of major monohydroxyeicosatetraenoic acids in rat basophilic leukemia cells. ---
1272  1991 Signal transduction by interferon-alpha through arachidonic acid metabolism. BPB, IFNs, ISRE
1273  1991 Structural identification of cytochrome P450-dependent arachidonate metabolites formed by rabbit medullary thick ascending limb cells. 19-HETE, mTALH
1274  1991 Synthesis of eicosanoids by isolated guinea pig tracheocytes. IgG, LT
1275  1991 The effect of a salmon diet on blood clotting, platelet aggregation and fatty acids in normal adult men. DHA, EPA, FA, PA
1276  1991 The effect of adjuvant-induced arthritis on rat leukocyte membrane phospholipid fatty acid levels following fish oil feeding. EPA, PEC
1277  1991 The role of prostaglandin synthetase in the rate depressant effects and narcosis caused by ethanol. PES
1278  1991 Thiol modification in H2O2- and thromboxane-induced vaso- and bronchoconstriction in rat perfused lung. ---
1279  1991 Thromboxane and prostacyclin generation by human umbilical veins after thrombin. HUV, TXB2
1280  1991 Treatment of S antigen uveoretinitis with lipoxygenase and cyclo-oxygenase inhibitors. CO, LO, NDGA
1281  1991 Tumor necrosis factor-alpha priming of phospholipase A2 activation in human neutrophils. An alternative mechanism of priming. DG, LTB4, PAF, PLA2
1282  1991 Tumoricidal action of cis-unsaturated fatty acids and their relationship to free radicals and lipid peroxidation. c-UFAs, EPA, GLA
1283  1991 Voltage dependence of bovine pulmonary artery endothelial cell function. ---
1284  1991 [Are omega-3-fatty acids essential for newborn infants?]. DHA, EPA
1285  1991 [Effect of (+)-S-145 calcium salt dihydrate, an orally active antagonist of the thromboxane A2/prostaglandin endoperoxide receptor, on platelet aggregation]. ---
1286  1991 [Effects of berberine on synthesis of platelet TXA2 and plasma PGI2 in rabbits]. ---
1287  1991 [Effects of econazole and clotrimazole on TXB2 and PGE2 production in calcimycin-stimulated neutrophils and arachidonic acid-stimulated platelets]. ---
1288  1991 [Effects of Y-20811, a specific thromboxane A2 synthetase inhibitor, on chemical mediator-induced bronchoconstriction in guinea pigs]. ---
1289  1991 [Evaluation of platelet malondialdehyde and 12-hydroperoxyeicosatetraenoic acid in type I and II diabetic patients with ketoacidosis and after clinical complications]. 12-HPETE, CO, LO, MDA
1290  1991 [The anti-pyretic mechanism of alminoprofen]. AP, CSF, i.c, LP, LPS
1291  1991 [The effects of ilexonin A on AA metabolism]. TXB2
1292  1992 5c,11c,14c-eicosatrienoic acid and 5c,11c,14c,17c-eicosatetraenoic acid of Biota orientalis seed oil affect lipid metabolism in the rat. ALA, BSO, GLA, LA, PC, PUFA
1293  1992 A role for the arachidonic acid cascade in fast synaptic modulation: ion channels and transmitter uptake systems as target proteins. NMDA, PUFA
1294  1992 Actions of SQ 29,548 on contractile responses and arachidonic acid metabolism of intrapulmonary arteries, in vitro. 5-HT, IPA, IPV, TX
1295  1992 Activation of T84 cell chloride channels by carbachol involves a phosphoinositide-coupled muscarinic M3 receptor. 4-DAMP
1296  1992 Activation of the human neutrophil 5-lipoxygenase by leukotriene B4. 15-HpETE, 5,15-DiHETE, 5-LO, LTB4
1297  1992 Active metabolism of arachidonic acid by Kaposi sarcoma cells cultured from lung biopsies (KS-3); identification by HPLC and MS/MS of the predominant metabolite secreted as the 11,12-epoxy-eicosatrienoic acid. EET, H-UVE, HMSM
1298  1992 Age-dependence of responses to acute ozone exposure in rats. PGE2, PMN
1299  1992 Age-related changes in renal cytochrome P-450 arachidonic acid metabolism in spontaneously hypertensive rats. DHT, EET, HETE, SHR
1300  1992 Alterations in eicosanoid production by rat alveolar type II cells isolated after silica-induced lung injury. LTC4, PG, TXB2
1301  1992 Anoxia induces phospholipase A2 activation in rabbit renal proximal tubules. PE, PLA2
1302  1992 Antiflammins suppress the A23187- and arachidonic acid-dependent chloride secretion in rabbit distal colonic mucosa. PGE2
1303  1992 Arachidonic acid and lipoxygenase metabolites uncouple neonatal rat cardiac myocyte pairs. ---
1304  1992 Arachidonic acid channelling in the phospholipid fractions and subcellular compartments of cultured myocardial cells. ---
1305  1992 Arachidonic acid induces phosphorylation of an 18 kDa protein in electrically permeabilised rat islets of Langerhans. 4 beta PMA, PKC
1306  1992 Arachidonic acid inhibits Cl secretion in cultures of dog tracheal epithelium. INDO, Isc, ISO, NDGA
1307  1992 Arachidonic acid inhibits myosin light chain phosphatase and sensitizes smooth muscle to calcium. ---
1308  1992 Arachidonic acid inhibits the secretory K+ channel of cortical collecting duct of rat kidney. CCD
1309  1992 Arachidonic acid metabolism in gill homogenate and isolated gill cells from rainbow trout, Oncorhynchus mykiss: the effect of osmolality, electrolytes and prolactin. ---
1310  1992 Arachidonic acid production by microorganisms. ---
1311  1992 Arachidonic acid regulates the phosphoinositide signal transduction pathway in submandibular acinar cells. ---
1312  1992 Arachidonic acid-induced insulin secretion from rat islets of Langerhans. PKC
1313  1992 Arachidonic acid-induced LH release is ATP-independent and insensitive to N-ethyl maleimide. ---
1314  1992 Bay K 8644 is a negative inotrope in the presence of arachidonic acid but not eicosapentaenoic acid. EPA
1315  1992 Beneficial effects of SK&F 105809, a novel cytokine-suppressive agent, in murine models of endotoxin shock. D-gal, IL-1, LPS, TNF
1316  1992 Bioactivation of aflatoxin B1 by lipoxygenases, prostaglandin H synthase and cytochrome P450 monooxygenase in guinea-pig tissues. AFB1, Hb, PHS, TMPD
1317  1992 Blocking the interleukin-1 receptor inhibits leukotriene B4 and prostaglandin E2 generation in human monocyte cultures. IL-1ra, PGE2
1318  1992 Carbachol-stimulated release of arachidonic acid and eicosanoids from brain cortex synaptoneurosome lipids of adult and aged rats. PI, PLA2, PLC
1319  1992 Cellular interactions between n-6 and n-3 fatty acids: a mass analysis of fatty acid elongation/desaturation, distribution among complex lipids, and conversion to eicosanoids. DHLA, EPA
1320  1992 Characterization and identification of an epidermal-growth-factor-activated phospholipase A2. EGF, PLA2
1321  1992 Characterization of a new compound, S35b, as a guanylate cyclase activator in human platelets. ---
1322  1992 Comparison of the effects of dietary fish oils with different n-3 polyunsaturated fatty acid compositions on plasma and liver lipids in rats. EPA
1323  1992 Complex effects of arachidonic acid and its lipoxygenase products on cytosolic calcium in GH3 cells. ---
1324  1992 Cytotoxicity of fatty acid oxygenase activation in rat basophilic leukemia cells. LA
1325  1992 Developmental changes in the fatty acids of rat uterus and the influence of dietary essential fatty acids. DHA, EPA, NL, PL
1326  1992 Dicentrine, a novel antiplatelet agent inhibiting thromboxane formation and increasing the cyclic AMP level of rabbit platelets. PAF
1327  1992 Dietary modulation of lipid metabolism and mechanical performance of the heart. DHA, EPA, PUFA's
1328  1992 Diethyldithiocarbamate (ditiocarb sodium) effect on arachidonic acid metabolism in human mononuclear cells. Glutathione peroxidase-like activity. 15-HPETE, Con A, DTC, GPx, HETE, PBMC, TXB2
1329  1992 Different patterns of release of endothelium-derived relaxing factor and prostacyclin. ACh, ADP, BK, EC, EDRF, Fb
1330  1992 Differential effects of WEB 2086 and SRI 63-441 on TNF-alpha-induced alterations in cardiopulmonary function. CI, PAF, PG, PVR, TX
1331  1992 Differential low density lipoprotein receptor-dependent formation of eicosanoids in human blood-derived monocytes. LDLs, LT, PG
1332  1992 Diminished arachidonic acid metabolite release by bovine alveolar macrophages exposed to surface-modified silica. BAM, PVPNO
1333  1992 Does gentamicin induce acute renal failure by increasing renal TXA2 synthesis in rats? ARF, Ccr, GM, IS, PU, VE
1334  1992 Dual action of arachidonic acid on calcium mobilization in avian granulosa cells. ER, LH
1335  1992 Dual regulation of arachidonic acid release by P2U purinergic receptors in dibutyryl cyclic AMP-differentiated HL60 cells. ---
1336  1992 Effect of a high concentration perfluorocarbon emulsion on platelet function. PFC
1337  1992 Effect of acute and chronic treatment of tin on blood pressure in spontaneously hypertensive rats. BP, SHR
1338  1992 Effect of age on leukotriene B4 production in guinea pig whole blood. 12-HETE, ELISA, LT, PGE2, PLA2, RP-HPLC, TXB2
1339  1992 Effect of anethole dithiolthione on human platelet aggregation. ADP, ADT, TX
1340  1992 Effect of dihomogammalinolenic acid and its 15-lipoxygenase metabolite on eicosanoid metabolism by human mononuclear leukocytes in vitro: selective inhibition of the 5-lipoxygenase pathway. 15-HETrE, CO, HPML, LO, PGE1, RP-HPLC
1341  1992 Effect of exogenous arachidonic acid metabolites applied on round window membrane on hearing and their levels in the perilymph. 15-HETE, ABR, HPLC, LT, PG, RIA, RWM
1342  1992 Effect of n-3 and n-6 dietary fats on the lipoxygenase products from stimulated rat neutrophils. EPA, LT
1343  1992 Effect of parathyroid hormone on arachidonic acid metabolism in mouse osteoblasts: permissive action of dexamethasone. ---
1344  1992 Effect of phorbol myristate acetate on release of arachidonic acid and its metabolites in the osteoblastic MOB 3-4 cell line and its subclone, MOB 3-4-F2. 4 alpha-PDD, PKC, PLA2, PMA
1345  1992 Effect of praziquantel and oxamniquine on prostacyclin synthesis by the rat arterial and myometrial tissues. PLA2
1346  1992 Effect of sodium loading (3% NaCl) on arachidonic acid biosynthesis in rat liver microsomes. DGLA, LA, PGs
1347  1992 Effect of steroids and nonsteroidal antiinflammatory agents on human ocular fibroblast. GFS, NSAIDs
1348  1992 Effect of sulindac on prostaglandin synthesis in human and in cultured rat renal and vascular smooth muscle cells. GM, PG, RPCT, VSM
1349  1992 Effect of tert-butyl hydroperoxide on cyclooxygenase and lipoxygenase metabolism of arachidonic acid in rabbit platelets. 12-HETE, 12-HPETE, HHT, t-BOOH, TX
1350  1992 Effect of tumor necrosis factor-alpha on the stimulus-coupled responses of neutrophils and their modulation by various inhibitors. fMLP, HPPMN, NA, OZ, PKC, PMA, PT, rHuTNF-alpha, TK
1351  1992 Effect of vegetable and marine oils in preterm infant formulas on blood arachidonic and docosahexaenoic acids. DHA
1352  1992 Effect of vitamin C and vitamin E on prostaglandin synthesis by fibroblasts and squamous carcinoma cells. PGs
1353  1992 Effects of a 5-lipoxygenase inhibitor, AA861, on lipoxygenase metabolism and superoxide anion generation by human polymorphonuclear leukocytes--potentiation of superoxide anion generation by LTB4. 5-HETE, LTB4, PMN
1354  1992 Effects of arachidonic acid, prostaglandin F2 alpha, prostaglandin E2, and arginine vasotocin on induction of birth in vivo and in vitro in a viviparous lizard (Sceloporus jarrovi). ---
1355  1992 Effects of butylated hydroxyanisole on arachidonic acid and linoleic acid metabolism in relation to gastrointestinal cell proliferation in the rat. ASA, BHA, IM, LA
1356  1992 Effects of cigarette smoking on the function of metabolizing arachidonic acid and angiotensin I in the isolated perfused rat lungs. AI
1357  1992 Effects of lipoxygenase and cyclooxygenase inhibitors on murine antibody-dependent cellular cytotoxicity (ADCC). ADCC, ASA, CO, ES, Imi, INDO, LO, NDGA, PHE
1358  1992 Effects of ozone exposure on lipid metabolism in human alveolar macrophages. AM, PAF
1359  1992 Effects of the amphiphilic peptides melittin and mastoparan on calcium influx, phosphoinositide breakdown and arachidonic acid release in rat pheochromocytoma PC12 cells. ---
1360  1992 Effects of the new antiplatelet agent 2-methyl-3-(1,4,5,6-tetrahydronicotinoyl)pyrazolo[1,5-a]pyridine on platelet aggregation and thrombosis in experimental animals. ASA, RPRP, TXB2
1361  1992 Eicosanoids modulate apical Ca(2+)-dependent K+ channels in cultured rabbit principal cells. CCT, PG, PLA2, Po
1362  1992 Eicosapentaenoic acid inhibits antigen-presenting cell function of murine splenocytes. APC, EPA, KLH
1363  1992 Eicosapentaenoic acid inhibits cholesteryl ester accumulation in rat peritoneal macrophages by decreasing the number of specific binding sites of acetyl LDL. AcLDL, CE, DHA, DPA, EPA, EPA-E
1364  1992 Eicosatetraynoic and arachidonic acid-induced changes in cell membrane fluidity consonant with differences in computer-aided design-structures. ---
1365  1992 Electrophysiological responses of the cochlea to transient asphyxia are influenced by arachidonate metabolites. CM, EP, SP
1366  1992 Endothelin-1 induces stimulation of prostaglandin synthesis in cells obtained from canine airways by bronchoalveolar lavage. BAL, ET-1, PG, TX
1367  1992 Endothelin-1 stimulates eicosanoid production in cultured human nasal mucosa. 15-HETE, ET, HPLC, PG
1368  1992 Endothelin-evoked Release of Arachidonic Acid from Mouse Astrocytes in Primary Culture. ET, PMA
1369  1992 Endotoxin tolerance is associated with altered GTP-binding protein function. GTPase, TXB2
1370  1992 Entamoeba histolytica alters arachidonic acid metabolism in macrophages in vitro and in vivo. INDO, LTC4, NDGA, p.i, PGE2, PMO
1371  1992 Epidermal derived growth factor stimulates the prostaglandin F2 alpha-synthesis in rabbit luteal cells. ---
1372  1992 Epithelial strips: an alternative technique for examining arachidonate metabolism in equine tracheal epithelium. PG
1373  1992 Extracellular ATP and ADP stimulate proliferation of porcine aortic smooth muscle cells. PDBu, PGE2, PKC, SMC
1374  1992 Factors affecting long-chain polyunsaturated fatty acid composition of plasma choline phosphoglycerides in preterm infants. DHA, EDD, LCPUFA
1375  1992 Fatty acid changes during the induction of differentiation of human promyelocytic leukemia (HL-60) cells by phorbolmyristate acetate. PMA
1376  1992 Generation of 5-lipoxygenase metabolites following pulmonary reperfusion in isolated rabbit lungs. ---
1377  1992 Gonadotropin releasing hormone activates the lipoxygenase pathway in cultured pituitary cells: role in gonadotropin secretion and evidence for a novel autocrine/paracrine loop. PGE
1378  1992 Guinea pig whole blood 5-lipoxygenase assay: utility in the assessment of potential 5-lipoxygenase inhibitors. LTB4, TXB2
1379  1992 Human keratinocyte sensitivity towards inflammatory cytokines varies with culture time. IL-1, PG
1380  1992 Human neutrophil-derived histamine-releasing activity (HRA-N) causes the release of serotonin but not arachidonic acid metabolites from rat basophilic leukemia cells. HRA-N, LTC4, PGD2, RBL
1381  1992 Hydrogen peroxide increases the availability of arachidonic acid for oxidative metabolism by inhibiting acylation into phospholipids in the alveolar macrophage. AM, PLA2
1382  1992 IgE binding inhibits arachidonic acid-induced chemiluminescence of human platelets. ChL, IgE, IgG
1383  1992 IgE receptor-mediated arachidonic acid release by rat basophilic leukemia (RBL-2H3) cells: possible role in activating degranulation. InsPs, PI
1384  1992 In human monocytes interleukin-1 stimulates a phospholipase C active on phosphatidylcholine and inactive on phosphatidylinositol. DAG, IL-1, IPs, PC, PLA2, PLC
1385  1992 Incorporation of [14C] arachidonic acid into ovine conceptus and endometrial lipids. ---
1386  1992 Increased whole blood platelet aggregation in normal pregnancy can be prevented in vitro by aspirin and dazmegrel (UK38485). PAF, TXA2
1387  1992 Influence of N-phenyllinoleamide from toxic oil samples on the lipoxygenase metabolism of exogenous arachidonic acid in mouse peritoneal macrophages. 3H-12-HETE, MPM, NPLA, TOS
1388  1992 Inhibition of phospholipase A2 activity in guinea pig eosinophils by human recombinant IL-1 beta. PC, PLA2
1389  1992 Inhibition of platelet-activating factor fails to limit ischemia and reperfusion-induced myocardial damage. HR, LCX, MAP
1390  1992 Inhibitory effect of curcumin on fatty acid desaturation in Mortierella alpina 1S-4 and rat liver microsomes. DGLA
1391  1992 Inhibitory effect of rhynchophylline on platelet aggregation and thrombosis. MDA, PF4, Rhy, TXB2
1392  1992 Inhibitory effects of hyaluronan on [14C]arachidonic acid release from labeled human synovial fibroblasts. HA
1393  1992 Inhibitory effects of interleukin 6 on prostaglandin I2 production in cultured bovine vascular endothelial cells. BVECs, IL-6, PGI2
1394  1992 Insoluble immune complex-stimulated neutrophil leukotriene B4 production is dependent on Fc gamma RII and Fc gamma RIII and independent of pertussis toxin-sensitive signal transduction pathways. ICs, LTB4
1395  1992 Interaction of platelets and blood vessels--vascular injuries induced by platelet activation in vivo. ---
1396  1992 Interleukin-8 stimulates the formation of 15-hydroxy-eicosatetraenoic acid by human neutrophils in vitro. IL-8, LO, PMN
1397  1992 Intratumoral gamma-linoleic acid therapy of human gliomas. EPA, GLA
1398  1992 Involvement of arachidonic acid and its metabolites in the inhibitory effect of beta-adrenoceptor blocking drugs on blood platelets. ALP, ATE, MDA, MET, OXP, PRO, TXB2
1399  1992 Involvement of arachidonic acid cascade pathways in interleukin-6-stimulated corticotropin-releasing factor release in vitro. AAC, CLO, CRF, DEX, ETI, IL-6, IND, MBH, PLA2
1400  1992 LDL receptor-dependent polyunsaturated fatty acid transport and metabolism. LDL
1401  1992 Ligand-operated synthesis of 4-series and 5-series leukotrienes in human neutrophils: critical dependence on exogenous free fatty acid supply. 5-HETE, EPA, PUFAs
1402  1992 Lipids of selected molds grown for production of n-3 and n-6 polyunsaturated fatty acids. DHA, EPA, PUFA
1403  1992 Lipoprotein receptor mediated metabolism of [14C]arachidonic acid labeled chylomicron remnants by Hep G2 cells. LDL, TG
1404  1992 Loss of cytosolic 15-lipoxygenase activity in A23187-stimulated human leukocytes: involvement of a translocation process? 15-LO
1405  1992 Lower levels of lipid peroxidation in human platelets incubated with eicosapentaenoic acid. 12-HETE, 12-HPETE, EPA
1406  1992 Mechanism of prostaglandin E2-induced arachidonic acid release in osteoblast-like cells: independence from phosphoinositide hydrolysis. PGE2, PTX
1407  1992 Metabolism of arachidonic, eicosapentaenoic, and docosahexaenoic acids in HepG2 cells and rat hepatocytes. DHA, EPA
1408  1992 Mobilization of diacylglycerol in intact HeLa cells by exogenous phospholipase C from Cl. perfringens is accompanied by release of fatty acids including arachidonic acid. DAG, PC, PI, PLC
1409  1992 Modulation of voltage-dependent Ca channel current by arachidonic acid and other long-chain fatty acids in rabbit intestinal smooth muscle. ---
1410  1992 Mouse peritoneal macrophages contain an acylating system specific for twenty-carbon polyunsaturated fatty acids. A study with intact cells. EPA, ETA
1411  1992 New indole and triazino[5,4-b]indol-4-one derivatives: synthesis and studies as inotropics and inhibitors of blood platelet aggregation. ADP, PGE2, TXB2
1412  1992 Nicardipine reduces the levels of leukotriene C4 and prostaglandin E2, following different ischemic periods in rat brain tissue. LTC4, PGE2
1413  1992 Papaverine effects on PGI2 and TXA2 release from the canine vascular wall. ---
1414  1992 Participation of prostaglandin E2 in dopamine D2 receptor-dependent potentiation of arachidonic acid release. CHO, PG
1415  1992 Phenytoin potentiates interleukin-1-induced prostaglandin biosynthesis in human gingival fibroblasts. PGE2, PHT, TNF-alpha
1416  1992 Phospholipase-A2 action and arachidonic acid metabolism in calcium-mediated parathyroid hormone secretion. LO, PLA2
1417  1992 Phospholipid metabolism and second messenger system after brain ischemia. APP, FFAs, IP3, PDBu, PKC, PPIs
1418  1992 Phosphorylation-dependent regulation of phospholipase A2 by G-proteins and Ca2+ in HL60 granulocytes. PLA2
1419  1992 Plasma and red blood cell fatty acid values as indexes of essential fatty acids in the developing organs of infants fed with milk or formulas. CNS, DHA, RBC
1420  1992 Platelet hyperreactivity in hyperlipidaemia with specific reference to platelet lipids and fatty acid composition. HL, PI, TX
1421  1992 Prolonged stimulation of bovine adrenal chromaffin cells with arachidonic acid and prostaglandin E2 increases expression of the proenkephalin gene and the secretion of [Met5]-enkephalin. BAMC, PGE2, proENK
1422  1992 Prostaglandin E2 and leukotriene C4 levels following different reperfusion periods in rat brain correlated with morphological changes. LTC4, PGE2
1423  1992 Prostaglandin E2 synthesis elicited by adrenergic stimuli in guinea pig trachea is mediated primarily via activation of beta 2 adrenergic receptors. iPGE2, PG
1424  1992 Prostaglandin E2-induced arachidonic acid release and catecholamine secretion from cultured bovine adrenal chromaffin cells. PGE2
1425  1992 Protective effects of benidipine on arachidonic acid-induced acute cerebral ischemia in rats. EB
1426  1992 Protein kinase C activation amplifies prostaglandin F2 alpha-induced prostaglandin E2 synthesis in osteoblast-like cells. OAG, PGE2, PGF2 alpha, PKC, TPA
1427  1992 Protein kinase C activation modulates arachidonic acid metabolism in cultured alveolar epithelial cells. PKC, PMA
1428  1992 Rapid remodeling of arachidonate from phosphatidylcholine to phosphatidylethanolamine pools during mast cell activation. BMMC, PC, PE, PI/PS
1429  1992 Rapid stimulation of 5-lipoxygenase activity in potato by the fungal elicitor arachidonic Acid. LOX
1430  1992 Reduced platelet thromboxane formation after long-term administration of a dihydropyridine calcium channel blocker: a prospective, double-blind, placebo-controlled study with nitrendipine in borderline hypertensive patients with IDDM-type diabetes mellitus. ---
1431  1992 Reduced tissue arachidonic acid concentration with chronic ethanol feeding in miniature pigs. ---
1432  1992 Regulation of arachidonic acid metabolism in the perinatal brain during development and under ischemic stress. DG, poly-PI
1433  1992 Regulation of phospholipase A2 activation and arachidonic acid metabolism in an interleukin-3-dependent macrophage-like cell line. IL-3, LTB4, PGE2, PKC, PLA2, PMA
1434  1992 Relevance of vasoactive mediators for the blood pressure effects of intravenous arachidonic acid injection in rats. ---
1435  1992 Retrograde modulation at developing neuromuscular synapses: involvement of G protein and arachidonic acid cascade. ACh, SSCs
1436  1992 Role of arachidonic acid and its metabolites in the regulation of progesterone and oxytocin release from the bovine corpus luteum. OT
1437  1992 Role of serine esterase in hydrogen peroxide-mediated activation of phospholipase A2 in rabbit pulmonary arterial smooth muscle cells. ---
1438  1992 Sequential incorporation of 3H- and 14C-arachidonic acid during 24 h in rabbit colonic explants cultured in vitro. PE, PI, PMA
1439  1992 Simultaneous measurement of fluid and protein permeability in isolated rabbit lungs during edema. ---
1440  1992 Spreading of HeLa cells on a collagen substratum requires a second messenger formed by the lipoxygenase metabolism of arachidonic acid released by collagen receptor clustering. LOX, PKC
1441  1992 Storage in sodium chloride does not impair arterial prostacyclin release. HBSS
1442  1992 Synthesis of eicosanoids by circulating mononuclears in healthy people and in patients with liver cirrhosis. LC, MNCs
1443  1992 Synthesis of prostaglandin F2 alpha, E2 and prostacyclin in isolated corpora lutea of adult pseudopregnant rats throughout the luteal life-span. CL, PGs, TXB2
1444  1992 Temporal and regional production of 12(S)hydroxyeicosatetraenoic acid [12(S)-HETE] in rat lens. ---
1445  1992 The activities of acyl-CoA:1-acyl-lysophospholipid acyltransferase(s) in human platelets. EPA, Lyso-PC
1446  1992 The cumulative dose response effect of eicosapentaenoic and docosahexaenoic acid on blood pressure, plasma lipid profile and diet pattern in mild to moderate essential hypertensive black patients. DHA, EPA
1447  1992 The effect of ascorbic acid on arachidonic acid and prostaglandin E2 metabolism in B16 murine melanoma cells. ASC, FA, PGE2
1448  1992 The effect of progesterone and human interferon alpha-2 on the release of PGF2 alpha and PGE from epithelial cells of human proliferative endometrium. PG
1449  1992 The effects of varying doses of aspirin on human platelet activation induced by PAF, collagen and arachidonic acid. PAF
1450  1992 The metabotropic glutamate receptor (MGR): pharmacology and subcellular location. AMPA, D, L-AP3, DO, InsP, KA, MGR, PDBu, trans-ACPD
1451  1992 The regulation of prostaglandin biosynthesis in cells derived from human gestational tissues: effects of fetal calf serum. FCS, PGE2
1452  1992 The renal cytochrome P-450 arachidonic acid system. ---
1453  1992 Tissue levels of polyunsaturated fatty acids during early human development. DHA
1454  1992 Tracheal epithelial cell fatty acid composition modulates prostaglandin E2 and cAMP production. cAMP, FBS, PGE2, TE
1455  1992 Transcellular metabolism of arachidonic acid: increased platelet thromboxane generation in the presence of activated polymorphonuclear leukocytes. fMLP, PMN, TX
1456  1992 Transduction of a signal for arachidonic acid metabolism by untriggered CSF-1 receptor induces an opposite effect to that induced by CSF-1 receptor and its ligand: separate regulation of phospholipase A2 and cyclooxygenase by CSF-1 receptor/CSF-1. PGE2, TK
1457  1992 Trichothecene mycotoxins inhibit phosphoinositide hydrolysis in bovine platelets stimulated with platelet activating factor. DAS, DON, PA, PAF, PI, PLC
1458  1992 Tumour promoter-induced release and metabolism of arachidonic acid: Comparison between mouse and human epidermal cells. HEK, MEK, PG, TPA
1459  1992 Type II alveolar epithelial eicosanoid metabolism: predominance of cyclooxygenase pathways and transcellular lipoxygenase metabolism in co-culture with neutrophils. HETE, LT, PG, PMN
1460  1992 Vessel repair after balloon angioplasty: morphological appearance and prostacyclin synthesising capacity. SMC
1461  1992 [Blood leukotriene B4 response to endotoxin in fish oil fed rats]. EPA, LPS, LTB4, SO
1462  1992 [Changes in arachidonic acid-induced respiratory distress in streptozotocin-diabetic mice]. STZ, TXA2
1463  1992 [Effect of bradykinin, ionophore A23187 and trypsin on prostacyclin release from calf and pig aorta endothelial cells]. ---
1464  1992 [Effect of dietary supplementation with eicosapentaenoic acid on surgically induced endometriosis in the rabbit]. EPA
1465  1992 [Effects of arachidonic acid, eicosapentaenoic acid and docosahexaenoic acid on tension of rabbit aortic strips]. DHA, EDCF, EPA
1466  1992 [Experimental study of the prostacyclin production of autogeneous vein graft]. AVG
1467  1992 [Pharmacological activities of musk. IV. Effects of musk on arachidonic acid metabolism in leukocytes from rat inflammatory exudate]. LTB4, PLA2
1468  1993 14(R),15(S)-epoxyeicosatrienoic acid (14(R),15(S)-EET) receptor in guinea pig mononuclear cell membranes. GPM
1469  1993 15-Hydroxy-eicosatetraenoic acid has minor anti-inflammatory properties in colitis. DSS
1470  1993 5-Lipoxygenase activity in the human pancreas. 5-LO, LTs
1471  1993 Aci-reductones enhance interleukin-2-induced lymphocyte cytotoxicity. IL-2, LAK, PBMC, ROS
1472  1993 Activation of protein kinase C by arachidonic acid selectively enhances the phosphorylation of GAP-43 in nerve terminal membranes. DAG, LTP, PKC
1473  1993 Adhesive interactions of neutrophils and leukotriene synthesis. 5-HETE, 5-LO, LTB4, PMA
1474  1993 Albumin-binding proteins function in the receptor-mediated binding and transcytosis of albumin across cultured endothelial cells. ABP, BAEC, FITC, OA
1475  1993 Anti-inflammatory effects of eicosapentaenoic acid on experimental skin inflammation models. DHA, EPA, UVB
1476  1993 Antiplatelet activity of some prenylflavonoids. PAF
1477  1993 Antiplatelet principles from a food spice clove (Syzygium aromaticum L) [corrected]. CO
1478  1993 Arachidonic acid abolishes the mitogen-induced increase in cytosolic free Ca2+ and intracellular pHi in rat thymocytes. Con A, PHA
1479  1993 Arachidonic acid and cell signalling in the ovary and placenta. ---
1480  1993 Arachidonic acid and its metabolites increase Cai in cultured rat oligodendrocytes. Cai, OLGs
1481  1993 Arachidonic acid and prostaglandin E2 stimulate testosterone production by goldfish testis in vitro. ---
1482  1993 Arachidonic acid and the control of body pattern inHydra. 12-HETE, 9-HODE, DG, PKC
1483  1993 Arachidonic acid immunoregulation in lambs persistently infected with border disease virus. BD, FA, LTC4, PGD2
1484  1993 Arachidonic acid increases the activity of the assembled NADPH oxidase in cytoplasmic membranes and endosomes. FITC-dextran
1485  1993 Arachidonic acid inhibits sodium currents and synaptic transmission in cultured striatal neurons. ---
1486  1993 Arachidonic acid metabolism during early development of ovine embryos: a possible relationship to shedding of the zona pellucida. INDO
1487  1993 Arachidonic acid metabolism of rat peritoneal macrophages after passive sensitization and allergen challenge. ---
1488  1993 Arachidonic acid metabolites and haemodynamics of the neonate. PGI2, TXA2
1489  1993 Arachidonic acid metabolites in experimental otitis media and effects of anti-inflammatory drugs. ---
1490  1993 Arachidonic acid stimulates glucose uptake in cerebral cortical astrocytes. NE
1491  1993 Arachidonic acid stimulates interleukin-6 release from rat peritoneal macrophages in vitro: evidence for a prostacyclin-dependent mechanism. IL-6, TXB2
1492  1993 Arachidonic acid turnover and phospholipase A2 activity in neuronal growth cones. GCPs, PC, PI, PLA2
1493  1993 Arachidonic acid-induced insulin secretion from rat islets of Langerhans is not mediated by protein phosphorylation. NDGA, PKC
1494  1993 Aspirin fails to inhibit platelet aggregation in sheep. ---
1495  1993 Biosynthesis, structure and biological activity of hydroxyeicosatetraenoic acids in Hydra vulgaris. 11-HPETE, HETEs
1496  1993 Ca2+ release from platelet intracellular stores by thapsigargin and 2,5-di-(t-butyl)-1,4-benzohydroquinone: relationship to Ca2+ pools and relevance in platelet activation. TG
1497  1993 Calphostin C, a specific protein kinase C inhibitor, activates human neutrophils: effect on phospholipase A2 and aggregation. NDGA, PAF
1498  1993 Cellular activation by thromboxane A2 and other eicosanoids. COX, PLC, TXA2
1499  1993 Cellular mechanisms for orthovanadate-, phorbol ester-, and calcium ionophore-stimulated prostaglandin production in brook trout (Salvelinus fontinalis) follicles. PG, PMA
1500  1993 Changes in microsomal phospholipases and arachidonic acid in experimental alcoholic liver injury: relationship to cytochrome P-450 2E1 induction and conjugated diene formation. CYP2E1, PLA, PLC
1501  1993 Characteristics of arachidonic-acid-mediated brain protein kinase C activation: evidence for concentration-dependent heterogeneity. DG, DOC, HS, LS, PKC, PtdCho, PtdSer
1502  1993 Characterization of hormonally regulated and particulate-associated phospholipase A2 from bovine endothelial cells. BK, HR-PLA2, PLA2
1503  1993 Chemical nature and immunotoxicological properties of arachidonic acid degradation products formed by exposure to ozone. PMN
1504  1993 Cloricromene inhibits leukotriene formation by human polymorphonuclear leucocytes by suppressing arachidonate release from membrane phospholipids. LTB4, PMNs, STZ
1505  1993 Coexistence of two biochemically distinct phospholipase A2 activities in human platelet, monocyte, and neutrophil. HMM, HSF, PLA2
1506  1993 Combination of arachidonic acid and guanosine 5'-O-(3-thiotriphosphate) induce translocation of rac p21s to membrane and activation of NADPH oxidase in a cell-free system. ---
1507  1993 Comparative evaluation of arachidonic acid (AA)- and tetradecanoylphorbol acetate (TPA)-induced dermal inflammation. LTB4, TPA, TXB2
1508  1993 Comparison of uptake and incorporation of docosahexaenoic and arachidonic acids by frog retinas. DHA
1509  1993 Control of inositol polyphosphate-mediated calcium mobilization by arachidonic acid in pancreatic acinar cells of rats. 4-BPB, InsP5
1510  1993 Cytochrome P450-dependent arachidonate metabolites affect renal transport in the rabbit. ---
1511  1993 Dietary fish oil supplementation alters LTB4:LTB5 ratios but does not affect the expression of acute graft versus host disease in mice. DHA, EPA, GVHD, LTB4, PUFA
1512  1993 Dietary n-3 fatty acid effects on neutrophil lipid composition and mediator production. Influence of duration and dosage. DCHA, EPA
1513  1993 Differential involvement of phospholipase A2/arachidonic acid and phospholipase C/phosphoinositol pathways during cholecystokinin receptor activated Ca2+ oscillations in pancreatic acini. ER
1514  1993 Differential vasoconstrictor potencies of free fatty acids in the lung vasculature: 2-versus 3-series prostanoid generation. EPA, ETA, OA, PAL
1515  1993 Distribution of monohydroxy fatty acids in specific human epidermal phospholipids. LA, MHFAs, PC, PE, PI
1516  1993 Dopamine D2 receptor signaling via the arachidonic acid cascade: modulation by cAMP-dependent protein kinase A and prostaglandin E2. PG, PKA
1517  1993 Effect of anti-inflammatory compounds on edema formation and myeloperoxidase activity in the arachidonic acid-induced ear model in the mouse. MPO
1518  1993 Effect of high concentration perflubron emulsion on platelet function. PFC
1519  1993 Effect of milrinone in human platelet shape change, aggregation and thromboxane A2 synthesis: an in vitro study. INDO, MIL, PSC, TXA2, WB-PA
1520  1993 Effect of naftidrofuryl on platelet-induced vasospasm in vitro. Role of antiserotonergic actions. BCA
1521  1993 Effect of single oral dose of aspirin on human platelet functions and plasma plasminogen activator inhibitor-1. a-c, PAI-1
1522  1993 Effect of the choline acetyltransferase inhibitor (2-benzoylethyl)-trimethylammonium iodide (BETA) on human placental prostaglandin release and phospholipase A2 activity. ACh, PG, PGHS, PLA2
1523  1993 Effect of VLDL on the inhibition of arachidonic acid transformation by dexamethasone in cultured smooth muscle cells. PGI2, SMC, VLDL
1524  1993 Effects of a garlic-derived principle (ajoene) on aggregation and arachidonic acid metabolism in human blood platelets. ADP
1525  1993 Effects of eicosanoid metabolism inhibitors on growth of a human gastric tumour cell line (HGT). HGT
1526  1993 Effects of endogenous and exogenous n-3 and n-6 fatty acids on microsomal synthesis of docosahexaenoic acid in vitro. DHA, DPA, EPA, PUFA
1527  1993 Effects of exogenous eicosapentaenoic acid on generation of leukotriene C4 and leukotriene C5 by calcium ionophore-activated human eosinophils in vitro. EPA, LT
1528  1993 Effects of highly purified ethyl all-cis-5,8,11,14,17-icosapentaenoate (EPA-E) on rabbit platelets. ADP, EPA, EPA-E, TXB2
1529  1993 Effects of inhibitors of arachidonic acid metabolism on serotonin release from rat basophilic leukemia cells. ETYA, NDGA, RBL
1530  1993 Effects of interleukin-1 alpha on arachidonic acid metabolism in human osteosarcoma osteoblastic cells. CO, HETE, IL-1alpha, LO, PGE2
1531  1993 Effects of polyunsaturated fatty acids on the efficacy of antineoplastic agents toward L5178Y lymphoma cells. alpha-LNA, DEX, DHA, DRN, EPA, LA, MTC, OA
1532  1993 Effects of tetrandrine on production of leukotriene B4 and thromboxane B2 in rabbit blood. CaM, DEX, FLU, HPLC, LTB4, PLA2, RIA, Tet, TXB2
1533  1993 Eicosanoid production by intrauterine tissues before and after labor in short-term tissue culture. ---
1534  1993 Eicosanoid/thromboxane A2-independent and -dependent generation of lysoplasmenylethanolamine via phospholipase A2 in collagen-stimulated human platelets. TXA2
1535  1993 Elongation, desaturation, and esterification of essential fatty acids by fetal rat brain in vivo. DG, DHA, NG, PC, PI, PL, TG
1536  1993 Endothelins release 51Cr from cultured human cerebromicrovascular endothelium. LDH, PKC
1537  1993 Endothelium-dependent contractions in rabbit pulmonary artery are mediated by thromboxane A2. EDCF, HPLC, MeCh, PG, TX
1538  1993 Epidermal growth factor potentiates interleukin 1 and tumor necrosis factor-induced prostaglandin biosynthesis in human gingival fibroblasts. 3H-AA, EGF, IL-1, PGE2, TGF-alpha, TNF-alpha
1539  1993 Fluoride causes suppression of neurite outgrowth in human neuroblastoma via an influx of extracellular calcium. PI
1540  1993 Free radicals and lung disease. ROS
1541  1993 Further studies on the antioxidant role of pyrophosphate in model membranes. DPPC, DPPE, SAPC, TBARS
1542  1993 Gallbladder mucin, arachidonic acid, and bile lipids in patients who develop gallstones during weight reduction. BS, GBM
1543  1993 General anesthetics inhibit cytochrome P450 monooxygenases and arachidonic acid metabolism. ---
1544  1993 Guanine nucleotide-binding protein stimulates arachidonic acid metabolism in TEA3A1 thymic epithelial cells by stimulating release and inhibiting incorporation of arachidonic acid. G protein, PGE2
1545  1993 Heat shock in human neutrophils: superoxide generation is inhibited by a mechanism distinct from heat-denaturation of NADPH oxidase and is protected by heat shock proteins in thermotolerant cells. ActD, HSPs
1546  1993 Highly purified eicosapentaenoic acid attenuates tissue damage in experimental myocardial infarction. EPA, LTB4
1547  1993 Human bronchial epithelial cell dysfunction following in vitro exposure to nitrogen dioxide. BSA, CBF, ppb
1548  1993 Hyperoxia decreases cyclooxygenase activity in endothelial cells. CAEC, PAEC, PG
1549  1993 Immunoregulation of antitumor response; differential secretion of arachidonic acid metabolites by macrophages during stimulation in vitro with BCG and Corynebacterium parvum. PEC, PGs, TLC
1550  1993 In vivo effect of lipopolysaccharide on alveolar and peritoneal macrophages of rats: superoxide anion generation and 5-lipoxygenase metabolism of arachidonic acid. AM, LTB4, PM
1551  1993 Increased synthesis and secretion of a 14-kDa phospholipase A2 by guinea pig alveolar macrophages. Dissociation from arachidonic acid liberation and modulation by dexamethasone. AM, PLA2
1552  1993 Increased thromboxane A2 production at primary tumor site in metastasizing squamous cell carcinoma of the larynx. PG, TXB2
1553  1993 Influence of fatty acid anilides present in toxic oils on the metabolism of exogenous arachidonic acid in cultured human endothelial cells. FAA, LAA, OAA
1554  1993 Inhibition of collagen-induced platelet aggregation and adhesion by a pseudocyanide derivative of avicine isolated from Zanthoxylum integrifoliolum Merr. ---
1555  1993 Inhibitory effect of melanin precursors on arachidonic acid peroxidation. DHI
1556  1993 Inhibitory effect of melatonin on platelet activation induced by collagen and arachidonic acid. ADP
1557  1993 Inhibitory effects of inhibitors of arachidonic acid metabolism on the evolution of rat liver preneoplastic foci into nodules and hepatocellular carcinomas with or without phenobarbital exposure. ASA, BPB, PB, QU
1558  1993 Insulin secretion without the participation of arachidonic acid. GC
1559  1993 Interaction of dietary protein and alpha-linolenic acid on polyunsaturated fatty acid composition of liver microsomal phospholipids and eicosanoid production in streptozotocin-induced diabetic rats. CAS, EPA, PUFA, SOY
1560  1993 Interactions between arachidonic and eicosapentaenoic acids during their dioxygenase-dependent peroxidation. EPA
1561  1993 Interactions between the monocyte/macrophage and the vascular smooth muscle cell. Stimulation of mitogenesis by a soluble factor and of prostanoid synthesis by cell-cell contact. CM, IM, SMCs
1562  1993 Interferon (IFN)-alpha, IFN-gamma, interleukin (IL)-2, and arachidonic acid metabolites modulate IL-4-induced IgE synthesis similarly in healthy persons and in atopic dermatitis patients. IFN, IL, IL-4, NDGA, PBMCs
1563  1993 Interferon-gamma induces a phospholipase D-dependent release of arachidonic acid from endothelial cell membranes: a mechanism for protein kinase C activation. BPB, DAG, IFN-gamma, PA, PAPase, PC, PKC, PLA2, PLC, PLD
1564  1993 Interferon-gamma-stimulated and GTP-binding-proteins-mediated phospholipase A2 activation in human neuroblasts. G proteins, IFN-gamma, IFN-gammaR, NB, PLA2
1565  1993 Interleukin-1 increases 15-hydroxyeicosatetraenoic acid formation in cultured human endothelial cells. HETEs, IL-1
1566  1993 Interleukin-1-mediated phospholipid breakdown and arachidonic acid release in human synovial cells. IL-1, PC, PE, PGE2, PI, PLA2
1567  1993 Interplay between platelet-derived 5-hydroxytryptamine and arachidonic acid metabolites limits the thrombolytic efficacy of streptokinase against canine platelet-rich coronary thrombosis. 5-HT, SK
1568  1993 Involvement of phospholipase A2 activation and arachidonic acid metabolism in the cytotoxic functions of rat NK cells. Ab, CO, LO, LTB4, lysoPC, NDGA, p-BPB, PLA2
1569  1993 Killing of endothelial cells and release of arachidonic acid. Synergistic effects among hydrogen peroxide, membrane-damaging agents, cationic substances, and proteinases and their modulation by inhibitors. EC, LL, PLA2, SLS
1570  1993 Mammalian gonadotropin-releasing hormone increases PGF2 alpha production activating diacylglycerol lipase in Rana esculenta interrenal. DAG, DAGlipase, mGnRH, PGF2 alpha, PKC, PLA1, PLA2, PLC
1571  1993 Manganese exposure to PC-12 cells alters triacylglycerol metabolism and promotes neurite outgrowth. PC, TG
1572  1993 Mechanisms of platelet-derived growth factor-induced arachidonic acid release in Swiss 3T3 fibroblasts: the role of a localized increase in free Ca2+ concentration beneath the plasma membrane and the activation of protein kinase C. AM, PDGF, PKC, PLA2
1573  1993 Mechanisms of suppression of X-ray-induced transformation of 10T1/2 cells by lipopolysaccharide. BPB, DM, PLA2
1574  1993 Mediators of vascular and parenchymal mechanisms in secondary brain damage. BBB, BK, HA
1575  1993 Metabolism in frog retinal pigment epithelium of docosahexaenoic and arachidonic acids derived from rod outer segment membranes. FFA, ROS, RPE, TG
1576  1993 Metabolism of arachidonic acid by caruncular and allantochorionic tissues in cows with retained fetal membranes (RFM). EGF, HETE, LTB4, PAF, PGE2, PGF2 alpha, RFM, TXB2
1577  1993 Microdialysis measurements of PGD2, TXB2 and 6-KETO-PGF1 alpha in rat CA1 hippocampus during transient cerebral ischemia. ---
1578  1993 Mobilization of different arachidonate pools and their roles in the generation of leukotrienes and free arachidonic acid during immunologic activation of mast cells. LT, SAR
1579  1993 Modulation of lipid derived mediators by polyunsaturated fatty acids. DAG, DHA, FA, IP, PL, PLase, PUFA
1580  1993 Modulation of phorbol ester-associated events in epidermal cells by linoleate and arachidonate. LA, PG, TPA
1581  1993 Modulation of pulmonary vascular resistance and edema formation by short-term infusion of a 10% fish oil emulsion. PAP
1582  1993 Modulation of superoxide anion generation by manoalide, arachidonic acid and staurosporine in liver infiltrated neutrophils in a rat model of endotoxemia. LPS, PKC, PLA2, PMA, PMN, SAL-PMN
1583  1993 Oxy-radicals, lipid peroxides and essential fatty acids in patients with glomerular disorders. EFAs, PGs, PMA
1584  1993 Peritoneal lavage fluid alters patterns of eicosanoid production in murine bone marrow-derived and peritoneal macrophages: dependency on inflammatory state of the peritoneum. BMDM, GM-CSF, LTC4, PLA2
1585  1993 Pneumocystis carinii induces the release of arachidonic acid and its metabolites from alveolar macrophages. ---
1586  1993 Possible mechanisms of epinephrine actions in quin-2-loaded platelets refractory to arachidonic acid. MLC
1587  1993 Production of eicosanoids in response to endothelin-1 and identification of specific endothelin-1 binding sites in airway epithelial cells. ET-1, GC/MS, HETE, HLPC, PG, RIA
1588  1993 Profile of capsaicin-induced mouse ear oedema as neurogenic inflammatory model: comparison with arachidonic acid-induced ear oedema. 5-HT, CGRP, NKA, PAF, SP, VIP
1589  1993 Prostacyclin release in experimental diabetes: effects of evening primrose oil. ACh, CO, EPO
1590  1993 Regulation of CD11b/CD18 expression in human neutrophils by phospholipase A2. HPMNL, MLD, PLA2, SLD
1591  1993 Regulation of the electrogenic H+ channel in the plasma membrane of neutrophils: possible role of phospholipase A2, internal and external protons. BPB, PKC, PMA
1592  1993 Regulatory effect of arachidonic acid on the calcium transport system in rat liver nuclei. 5-HETE
1593  1993 Release of 6-keto-PGF1 alpha and thromboxane B2 in late appearing cardioprotection induced by the stable PGI analogue: 7-OXO-PGI. 6-KETO, 7-OXO, TXA2, TXB2
1594  1993 Requirement for diacylglycerol and protein kinase C in HeLa cell-substratum adhesion and their feedback amplification of arachidonic acid production for optimum cell spreading. DG, LOX, PKC, PLA2
1595  1993 Role of a membrane-associated serine esterase in the oxidant activation of phospholipase A2 by t-butyl hydroperoxide. PLA2, t-BuOOH, TAME
1596  1993 Role of eicosanoids in vasopressin-induced calcium mobilization in A7r5 vascular smooth muscle cells. HPLC
1597  1993 Role of protein kinase C in oxidant--mediated activation of phospholipase A2 in rabbit pulmonary arterial smooth muscle cells. PKC, PLA2
1598  1993 Role of serine esterase in A23187-mediated activation of phospholipase A2 in pulmonary endothelium. PLA2
1599  1993 SCF/c-kit receptor-mediated arachidonic acid liberation in rat mast cells. Involvement of PLD activation associated tyrosine phosphorylation. 1,2-DG, PA, SCF
1600  1993 Selection of alternative G-mediated signaling pathways at the dopamine D2 receptor by protein kinase C. PKC
1601  1993 Simple relationships exist between dietary linoleate and the n-6 fatty acids of human neutrophils and plasma. LA
1602  1993 Somatostatin inhibition of hippocampal CA1 pyramidal neurons: mediation by arachidonic acid and its metabolites. SS
1603  1993 Stimulation by glutamate receptors of arachidonic acid release depends on the Na+/Ca2+ exchanger in neuronal cells. AMPA, mGluR, NMDA, PLA2
1604  1993 Stimulation of prostaglandin synthesis by human endothelial cells exposed to hypoxia. PGs
1605  1993 Synthesis of 12-hydroxyeicosatetraenoic acid by human endometrium and decidua. 12-HETE, HPLC, PGs
1606  1993 The activation of phospholipase A2 and release of arachidonic acid and other lipid mediators at the synapse: the role of platelet-activating factor. DHA
1607  1993 The calcium uptake of the rat heart sarcoplasmic reticulum is altered by dietary lipid. CSR, DHA, EPA
1608  1993 The differential effect of aspirin on human platelet activation in aspirin-sensitive asthmatics and normal subjects. Col, PAF
1609  1993 The effect of ascorbate on essential fatty acid composition in B16 melanoma cells. DGLA, EFA, GLA, LA
1610  1993 The effect of methotrexate on lipoxygenase metabolism in neutrophils from rats: in vitro and ex vivo studies. 5-HETE, 5-LO, LTB4, MTX
1611  1993 The effect of nordihydroguaiaretic acid on leukotriene C4 and prostaglandin E2 production following different reperfusion periods in rat brain after forebrain ischemia correlated with morphological changes. LTC4, NDGA, PGE2
1612  1993 The enteral bioavailability of eicosapentaenoic acid and docosahexaenoic acid is as good from ethyl esters as from glyceryl esters in spite of lower hydrolytic rates by pancreatic lipase in vitro. ---
1613  1993 The genotoxic effects of arachidonic acid in V79 cells are mediated by peroxidation products. ---
1614  1993 The influence of growth factors on the prostaglandin synthesis in cultured rabbit luteal cells. PG
1615  1993 The mechanism of arachidonic acid-induced insulin secretion from rat islets of Langerhans. ---
1616  1993 The platelet-activating factor precursor of the injured cornea is selectively implicated in arachidonate and eicosanoid release. HPLC, PAF
1617  1993 The role of essential fatty acids in neural development: implications for perinatal nutrition. DHA
1618  1993 Time-dependent effects of progressive gamma-linolenate feeding on hyperphagia, weight gain, and erythrocyte fatty acid composition during growth of Zucker obese rats. GLA, PL, SOY
1619  1993 Transcellular eicosanoid synthesis in cocultures of alveolar epithelial cells and macrophages. AEC, AM
1620  1993 Ultraviolet radiation-induced phospholipase A2 activation occurs in mammalian cell membrane preparations. ---
1621  1993 Vitamin K2 (menatetrenone) inhibits prostaglandin synthesis in cultured human osteoblast-like periosteal cells by inhibiting prostaglandin H synthase activity. PG
1622  1993 [Effect of PAF (platelet-activating factor) on hemostasis. Studies on endothelial cells and platelets]. PAF, PRP
1623  1993 [Effect of quercetin on chemiluminescence of human platelets induced by arachidonic acid]. CL
1624  1993 [Nutrition as adjuvant therapy in chronic polyarthritis]. ---
1625  1993 [The dynamic production of interferons, interleukins and arachidonic acid metabolites by the blood cells of children with glomerulonephritis associated with HB virus infection while treated with reaferon]. GN, IFN, IL, IST
1626  1993 [The effect of oxytocin on production of free fatty acid in primary human uterine myometrial cell culture]. DHAS, LA, OT, PA, PI-PLC, SA
1627  1993 [The effect of the long-term use of a diet enriched with omega-3 polyunsaturated fatty acids on the fatty acid composition, fibrinolytic system indices and lipid spectrum of the blood in patients with ischemic heart disease]. DHA, EPA
1628  1994 1,3-Dioctanoylglycerol (1,3-DiC8) is as effective as 1,2-dioctanoylglycerol (1,2-DiC8) in priming phospholipase A2 activation in human platelets and neutrophils. DAG, OAG, PKC, PLA2, PMA
1629  1994 A dual effect of arachidonic acid on Ca2+ transport systems in lymphocytes. BHQ
1630  1994 A newly cloned phospholipase A2-activating protein elicits Ca2+ oscillations and pancreatic amylase secretion via mediation of G protein beta/phospholipase A2/arachidonic acid cascades. PLA2, PLAP
1631  1994 A phospholipase C inhibitor, U-73122, blocks TSH-induced inositol trisphosphate production, Ca2+ increase and arachidonic acid release in FRTL-5 thyroid cells. IP3, PLC
1632  1994 A study of the synergism between metabotropic glutamate receptor activation and arachidonic acid in the rat hippocampus. ACPD, PKC
1633  1994 Aging modulates calcium-dependent phosphatidylinositol degradation by cerebral cortex synaptic plasma membrane phospholipases. DAG, PLA2, PLC, SPM
1634  1994 Altered renal P-450 metabolism of arachidonic acid in Dahl salt-sensitive rats. 20-HETE
1635  1994 Antiaggregant and antivasospastic properties of the new thromboxane A2 receptor antagonist sodium 4-[[1-[[[(4-chlorophenyl)sulfonyl]amino]methyl]cyclopentyl] methyl]benzeneacetate. PRP
1636  1994 Antiarrhythmic effects of eicosapentaenoic acid during myocardial infarction--enhanced cardiac microsomal (Ca(2+)-Mg2+)-ATPase activity. EPA, VF, VT
1637  1994 Antiplatelet constituents of formosan Rubia akane. ---
1638  1994 Antiproliferative effect of polyunsaturated fatty acids and interleukin-2 on normal and abnormal human lymphocytes. ALA, DHA, EPA, GLA, IL-2, LA, PUFAs
1639  1994 Antithrombotic activity of clove oil. PAF
1640  1994 Arachidonic acid and lipoxygenase products stimulate gonadotropin alpha-subunit mRNA levels in pituitary alpha T3-1 cell line: role in gonadotropin releasing hormone action. 5-HETE, BPB, GnRH, LTC4
1641  1994 Arachidonic acid blocks large-conductance chloride channels in L6 myoblasts. ---
1642  1994 Arachidonic acid down-regulates the insulin-dependent glucose transporter gene (GLUT4) in 3T3-L1 adipocytes by inhibiting transcription and enhancing mRNA turnover. ---
1643  1994 Arachidonic acid induces [Ca2+]i oscillations in smooth muscle cells from human airways. PLA2
1644  1994 Arachidonic acid metabolism by nuclei of a retinoic acid--or vitamin D3-differentiated human leukemia cell line HL-60. HHT, PGs, RA, TXB2
1645  1994 Arachidonic acid metabolism in alveolar macrophages from actively sensitized guinea-pigs: effects of sensitization and specific allergen. sAM
1646  1994 Arachidonic acid mobilization in P388D1 macrophages is controlled by two distinct Ca(2+)-dependent phospholipase A2 enzymes. ---
1647  1994 Arachidonic acid participates in the anoxia-induced increase in mEPSC frequency in CA1 neurons of the rat hippocampus. aCSF, BPB, mEPSCs
1648  1994 Arachidonic acid release and permeability changes induced by endothelins in human cerebromicrovascular endothelium. ET-1, HBEC, PKC
1649  1994 Arachidonic acid stimulates the plasma membrane H+ conductance of macrophages. ---
1650  1994 Arachidonyl trifluoromethyl ketone, a potent inhibitor of 85-kDa phospholipase A2, blocks production of arachidonate and 12-hydroxyeicosatetraenoic acid by calcium ionophore-challenged platelets. 12-HETE, cPLA2
1651  1994 Assessment of membrane toxicity using [(3)H]arachidonic acid release in U937 cells. SDS
1652  1994 Augmented expression of cytosolic phospholipase A2 during phenotypic transformation of cultured type II pneumocytes. AEC, cPLA2, PLA2
1653  1994 Autocrine enhancement of leukotriene synthesis by endogenous leukotriene B4 and platelet-activating factor in human neutrophils. 5-LO, GM-CSF, LTB4, PAF, PT, rh
1654  1994 Bacterial lipopolysaccharide primes human neutrophils for enhanced release of arachidonic acid and causes phosphorylation of an 85-kD cytosolic phospholipase A2. LBP, LPS, LTB4, OA, PLA2
1655  1994 Bioactivation of arachidonic acid by the cytochrome P450 monooxygenases of guinea pig lung: the orthologue of cytochrome P450 2B4 is solely responsible for formation of epoxyeicosatrienoic acids. EETs
1656  1994 C-kinase manipulations disrupt activity-driven retinotopic sharpening in regenerating goldfish retinotectal projection. i.o, IC, LTP, PKC
1657  1994 Ca-mediated and independent effects of arachidonic acid on gap junctions and Ca-independent effects of oleic acid and halothane. DPPC, DWCC, OA
1658  1994 Calcium influx and protein kinase C alpha activation mediate arachidonic acid mobilization by the human NK-2 receptor expressed in Chinese hamster ovary cells. NK2
1659  1994 Candida albicans stimulates arachidonic acid liberation from alveolar macrophages through alpha-mannan and beta-glucan cell wall components. ---
1660  1994 Cellular mechanisms mediating the stimulation of ovine endometrial secretion of prostaglandin F2 alpha in response to oxytocin: role of phospholipase A2. PG, PL
1661  1994 Concentration-dependent modulations of potassium and calcium currents of rat osteoblastic cells by arachidonic acid. ---
1662  1994 Cytochrome P-450 arachidonate metabolites affect ion fluxes in rabbit medullary thick ascending limb. 20-HETE, mTALH
1663  1994 Diacylglycerol kinase is stimulated by arachidonic acid in neural membranes. DG, PA
1664  1994 Dietary lipids from marine unicellular algae enhance the amount of liver and blood omega-3 fatty acids in rats. DHA, EPA, PUFA
1665  1994 Differential effect of growth- and differentiation-inducing factors on the release of eicosanoids and phospholipids from ML-1 human myeloblastic leukemia cells. HETEs, IGF1, Tf, TGF-beta
1666  1994 Differential effects of eicosapentaenoic acid and docosahexaenoic acid on human skin fibroblasts. DHA, EPA
1667  1994 Differential effects of phorbol 12-myristate 13-acetate and diacylglycerols on thromboxane A2-independent phospholipase A2 activation in collage-stimulated human platelets. PKC, PLA2, PMA, TXA2
1668  1994 Differential induction of eicosanoid synthesis in monocytic cells treated with retinoic acid and 1,25-dihydroxy-vitamin D3. GC-MS, HHT, IFN-gamma, PAF, RA
1669  1994 Differential roles for triglyceride and phospholipid pools of arachidonic acid in human lung macrophages. BMP, HLM, PC, PE, PI/PS, TG
1670  1994 Docosahexaenoic acid and signaling pathways in rabbit colon. DHA, PG
1671  1994 Effect of a 5-lipoxygenase inhibitor, ZM 230487, on cutaneous allergic inflammation in the guinea-pig. LTB4, PCA
1672  1994 Effect of administration of gamma-linolenic acid on the fatty acid composition of serum phospholipids and cholesteryl esters in patients with cystic fibrosis. CE, PL
1673  1994 Effect of bacterial cell wall and lipopolysaccharide on arachidonic acid metabolism by caruncular and allantochorionic tissues from cows that calved normally and those that retained fetal membranes. HETE
1674  1994 Effect of dipfluzine on platelet aggregation and thrombus formation. CIN, Dip
1675  1994 Effect of interleukin 1, lipopolysaccharide and phorbol esters on phospholipase D activity in chondrocytes. IL-1, LPS, PGE2, PKC, PLD, PMA
1676  1994 Effect of n-3 and n-6 fatty acids on proliferation and differentiation of promyelocytic leukemic HL-60 cells. EPA, RA
1677  1994 Effect of n-6 and n-3 fatty acids on the survival of vincristine sensitive and resistant human cervical carcinoma cells in vitro. CPZ, DGLA, DHA, EPA, GLA, NDGA, SOD, TFP
1678  1994 Effect of P-450 omega-hydroxylase metabolites of arachidonic acid on tubuloglomerular feedback. 17-ODYA, SFP, TGF
1679  1994 Effect of picotamide on the calcium mobilization and phospholipase C activation in human platelets. GFPs, Ins 1,3,4 P3, PLC, TXA2
1680  1994 Effect of polyunsaturated fatty acids on the growth of murine colon adenocarcinomas in vitro and in vivo. LA, PUFAs
1681  1994 Effect of prostaglandins and their precursors on the proliferation of human lymphocytes and their secretion of tumor necrosis factor and various interleukins. DGLA, EPA, ILs, PGs, TNF, TXB2
1682  1994 Effects of CGRP in different models of mouse ear inflammation. CA, CGRP, CO, TPA
1683  1994 Effects of continuous tube feeding of dietary fat emulsions on eicosanoid production and on fatty acid composition during an acute septic shock in rats. EPA, LPS, MO, PG, PUFA, SO
1684  1994 Effects of long-chain polyunsaturated fatty acids on the contraction of neonatal rat cardiac myocytes. DHA, EPA, ETYA, PUFAs
1685  1994 Effects of organometals on cellular signaling. I. Influence of metabolic inhibitors on metal-induced arachidonic acid liberation. PLA2, PT
1686  1994 Effects of tebufelone (NE-11740), a new anti-inflammatory drug, on arachidonic acid metabolism. 5-LO, CO, DTBP, NSAID
1687  1994 Effects of the lipid peroxidation inhibitor tirilazad mesylate (U-74006F) on gerbil brain eicosanoid levels following ischemia and reperfusion. ---
1688  1994 Enantiospecific synthesis of bioactive hydroxyeicosatetraenoic acids (HETEs) in Hydra magnipapillata. 12-S-HPETE, EHF, HETEs, NDGA
1689  1994 Endothelium-dependent relaxation to arachidonic acid in porcine coronary artery: is there a fourth pathway? BK, CO, CP450, INDO, L-NAME, LO, NO, PCA, PLA
1690  1994 Endotoxin tolerance is associated with decreased prostaglandin H synthases-1 and -2. LPS, PG, TX
1691  1994 Evidence that secretory phospholipase A2 plays a role in arachidonic acid release and eicosanoid biosynthesis by mast cells. 5-LO, CO, sPLA2
1692  1994 Existence of an enzymatic pathway furnishing arachidonic acid for prostaglandin synthesis from arachidonoyl CoA in rabbit kidney medulla. AA-CoA, PG
1693  1994 Expression of prostaglandin H2-mediated mechanism of vascular contraction in hypertensive rats. Relation to lipoxygenase and prostacyclin synthase activities. PG, TX
1694  1994 Facilitatory effect of docosahexaenoic acid on N-methyl-D-aspartate response in pyramidal neurones of rat cerebral cortex. DHA, NMDA
1695  1994 Fatty acid and amino acid composition in haruan as a potential role in wound healing. EPA
1696  1994 Fatty acid and phospholipid selectivity of different phospholipase A2 enzymes studied by using a mammalian membrane as substrate. CoA-IT, PLA2
1697  1994 Fatty acids directly increase the activity of Ca(2+)-activated K+ channels in rabbit coronary smooth muscle cells. ---
1698  1994 Formation and action of a P-450 4A metabolite of arachidonic acid in cat cerebral microvessels. HETE, ODYA
1699  1994 Glutamate exocytosis and MARCKS phosphorylation are enhanced by a metabotropic glutamate receptor coupled to a protein kinase C synergistically activated by diacylglycerol and arachidonic acid. MARCKS, mGluR, PKC
1700  1994 Glutamate uptake is inhibited by arachidonic acid and oxygen radicals via two distinct and additive mechanisms. BSA, CAT, DTT, ROS, SOD, XO
1701  1994 Histochemical demonstration of free radicals (H2O2) in ischemic brain edema and protective effects of human recombinant superoxide dismutase on ischemic neuronal damage. MDA
1702  1994 Identification of a substance, previously shown to enhance mitogenesis of human lymphocytes, as the acetamide of p-aminobenzoic acid. PACBA
1703  1994 Identification of arachidonic acid as a mediator of sphingomyelin hydrolysis in response to tumor necrosis factor alpha. SM, TNF-alpha
1704  1994 IL-1 beta amplifies bradykinin-induced prostaglandin E2 production via a phospholipase D-linked mechanism. BK, DAG, PA, PC, PEt, PLC, PLD
1705  1994 Incorporation of exogenous unsaturated fatty acids in mouse jejunal explants. ---
1706  1994 Increase in cytosolic free Ca2+ in corticotropin-stimulated white adipocytes. ACTH, NE, PC, PI
1707  1994 Increases in 5-lipoxygenase activating protein expression account for enhanced capacity for 5-lipoxygenase metabolism that accompanies differentiation of peripheral blood monocytes into alveolar macrophages. 5-LO, AM, FLAP, PBM
1708  1994 Influence of thiofedrine on platelet aggregation, intraplatelet cyclic cAMP and malondialdehyde in rats. ADP, cAMP, MDA, Thi
1709  1994 Influences on the gamma-muscle-spindle system from muscle afferents stimulated by increased intramuscular concentrations of arachidonic acid. MSAs, PBSt
1710  1994 Inhibition by fatty acids of cyclic AMP-dependent protein kinase activity in brush border membranes isolated from human placental vesicles. BBM, INDO, NDGA, PKA
1711  1994 Inhibition of adenylate cyclase in perfusion mouse palate by secalonic acid D. AC, CP, GC, PG, SAD
1712  1994 Inhibition of cyclooxygenase activity and increase in platelet cyclic AMP by girinimbine, isolated from Murraya euchrestifolia. PAF, PGD2, PGE2, PRP, TXB2
1713  1994 Inhibition of human neutrophil leukotriene B4 synthesis in essential fatty acid deficiency: role of leukotriene A hydrolase. EFA, FA, LTA4, LTB4
1714  1994 Inhibition of renal vascular 20-HETE production impairs autoregulation of renal blood flow. 17-ODYA, 20-HETE, EETs
1715  1994 Inhibitory effect of 4-acylaminophenol derivatives (T-0799 and T-0757), novel lipoxygenase inhibitors, on arachidonic acid-induced infiltration of polymorphonuclear leukocytes in rat skin. MPO
1716  1994 Inhibitory effect of tetrahydroberberine on platelet aggregation and thrombosis. THB, TXB2
1717  1994 Interactions between large and small bovine luteal cells in a sequential perifusion co-culture system. ---
1718  1994 Interactions between protein kinase C and arachidonic acid in the gonadotropin response to salmon and chicken gonadotropin-releasing hormone-II in goldfish. BPB, DG, GTH, NDGA, PKC, PLA2, sGnRH, TPA
1719  1994 Interferon-gamma induces the synthesis and activation of cytosolic phospholipase A2. cPLA2, PLA2
1720  1994 Interleukin-4-mediated inhibition of C-Fos mRNA expression: role of the lipoxygenase directed pathway. 5'-HPTETE, LTB4
1721  1994 Interrelationship of ascorbate, arachidonic acid and prostaglandin E2 in B16 melanoma cells. AC, ASC, PGE2
1722  1994 Ketoconazole blocks organic osmolyte efflux independently of its effect on arachidonic acid conversion. LO, PG
1723  1994 Kinetics of 5-lipoxygenase activation, arachidonic acid release, and leukotriene synthesis in human neutrophils: effects of granulocyte-macrophage colony-stimulating factor. 5-LO, GM-CSF, LT
1724  1994 Light-evoked arachidonic acid release in the retina: illuminance/duration dependence and the effects of quinacrine, mellitin and lithium. Light-evoked arachidonic acid release. PLA2
1725  1994 Lovastatin increases arachidonic acid levels and stimulates thromboxane synthesis in human liver and monocytic cell lines. LOV, MM6
1726  1994 Macrophage colony-stimulating factor-induced bone marrow macrophages do not synthesize or release prostaglandin E2. FBS, GM, IL-3, M-CSF, MO, PGE2, PLA2, RIA
1727  1994 Mechanically induced calcium mobilization in cultured endothelial cells is dependent on actin and phospholipase. BAEC
1728  1994 Modulation of antitumour activity of macrophages by regulation of eicosanoids and cytokine production. CAPD, MO
1729  1994 Modulation of rat peripheral polymorphonuclear leukocyte response by nitric oxide and arginine. L-Arg, LCL, NO, PMNLs, SNP
1730  1994 Modulation of superoxide generation in in vivo lipopolysaccharide-primed Kupffer cells by staurosporine, okadaic acid, manoalide, arachidonic acid, genistein and sodium orthovanadate. 5-LO, CO, LPS, PKC, PLA2, PMA
1731  1994 Muscarinic cholinergic agonists stimulate arachidonic acid release from mouse striatal neurons in primary culture. IPs, PMA
1732  1994 Nitric oxide production regulates cGMP formation and calcium influx in pancreatic acinar cells. L-NMMA, NO
1733  1994 omega-Conotoxin inhibits glucose- and arachidonic acid-induced rises in intracellular [Ca2+] in rat pancreatic islet beta-cells. CTX, DHP, FACS
1734  1994 On the role of arachidonic acid in M-current modulation by muscarine in bullfrog sympathetic neurons. IA
1735  1994 Opposing actions of D1- and D2-dopamine receptors on arachidonic acid release and cyclic AMP production in striatal neurons. ---
1736  1994 Oxidative metabolism of aflatoxin B1 by lipoxygenase purified from human term placenta and intrauterine conceptal tissues. AFB1, LA, LO
1737  1994 Oxidized low density lipoprotein increases U937 cell 5-lipoxygenase activity: induction of 5-lipoxygenase activating protein. 15-HETE, 5-HETE, 5-LO, oxLDL
1738  1994 P2-purinergic stimulation of iodide efflux in FRTL-5 rat thyroid cells involves parallel activation of PLC and PLA2. BAPTA, PKC, PLA2, PLC
1739  1994 Paradoxical inhibition by aspirin of naloxone-induced adrenocorticotropin secretion in myotonic dystrophy. DM
1740  1994 Parathyroid hormone inhibits Na(+)-K(+)-ATPase through a cytochrome P-450 pathway. 20-HETE, PLA2, PT, PTH, PTX
1741  1994 Pharmacokinetic and pharmacodynamic profiles of CS-518, a selective, long-lasting thromboxane synthase inhibitor, after single and multiple oral administration to healthy volunteers. 6-keto-PGF1 alpha, ADP, AUC, TX
1742  1994 Pharmacological characterization of cinnamophilin, a novel dual inhibitor of thromboxane synthase and thromboxane A2 receptor. i.p, PGE2, PRP, TXA2, TXB2
1743  1994 Phenol red is a thromboxane A2/prostaglandin H2 receptor antagonist in canine lingual arteries and human platelets. LA, PE, PGF2 alpha, PR
1744  1994 Phosphatidate-induced arachidonic acid mobilization in mouse peritoneal macrophages. PA
1745  1994 Platelet aggregation and dense granule secretion in schizophrenia. ATP
1746  1994 Polarized release of lipid mediators derived from phospholipase A2 activity in a human bronchial cell line. PAF, PLA2
1747  1994 Polymorphonuclear leukocyte-platelet interaction: role of P-selectin in thromboxane B2 and leukotriene C4 cooperative synthesis. ---
1748  1994 Potentiation by cholesterol and vitamin D3 oxygenated derivatives of arachidonic acid release and prostaglandin E2 synthesis induced by the epidermal growth factor in NRK 49F cells: the role of protein kinase C. EGF, PG, PKC
1749  1994 Protective effects of KW-3635, a thromboxane A2 antagonist, on arachidonic acid-induced transient cerebral ischemia in dogs. EEG, LCP, TX
1750  1994 Radiation reduces cyclooxygenase activity in cultured human endothelial cells at low doses. IL-2, PG, PGE2, PGF2 alpha
1751  1994 Reduced 5-lipoxygenase metabolism of arachidonic acid in macrophages rrom 1,25-dihydroxyvitamin D3-deficient rats. 5-LO, AM, COX, PBM, PM
1752  1994 Reduction in human neutrophil superoxide anion generation by n-3 polyunsaturated fatty acids: role of cyclooxygenase products and endothelium-derived relaxing factor. DHA, EDRF, EPA, NO, PMNs, SOD
1753  1994 Regulation of guanine-nucleotide binding proteins in islet subcellular fractions by phospholipase-derived lipid mediators of insulin secretion. LPA, LPC, PA, PC
1754  1994 Regulation of phospholipase A2 activity in undifferentiated and neutrophil-like HL60 cells. Linkage between impaired responses to agonists and absence of protein kinase C-dependent phosphorylation of cytosolic phospholipase A2. cPLA2, PMA
1755  1994 Regulation of prostaglandin synthesis by interleukin-1 beta in cultured bovine luteal cells. ActD, CHX, IL-1 beta, PGF2 alpha, PLA2, PLC
1756  1994 Relationship between plasma essential fatty acids and smoking, serum lipids, blood pressure and haemostatic and rheological factors. DHA, EPA, FIBDP, HDL-C, LPx, TGs, vWF
1757  1994 Relaxant responses of rabbit aorta: influence of cytochrome P450 inhibitors. ---
1758  1994 Relaxation of porcine coronary artery to bradykinin. Role of arachidonic acid. NO, PCA
1759  1994 Release and steroidogenic actions of polyunsaturated fatty acids in the goldfish testis. DHA, EPA, ETA, INDO, PG, PMA, PUFA
1760  1994 Role of the cytochrome P450 enzyme system as a humoral modulator of vasomotor responses in rat renal vasculature. 5-HT, cyt, PE
1761  1994 Serotonin, a potent modulator of arachidonic acid turnover, interaction with glutamatergic receptor in brain cortex. LPI, PI
1762  1994 Stimulated human gastric tumor cells (HGT) fail to synthesize eicosanoids. HGT
1763  1994 Studies on anti-platelet agents. IV. A series of 2-substituted 4,5-bis(4-methoxyphenyl)pyrimidines as novel anti-platelet agents. CO
1764  1994 Suppression of human T-cell growth in vitro by cis-unsaturated fatty acids: relationship to free radicals and lipid peroxidation. DGLA, EPA, PGE, PGs
1765  1994 Swelling, acidosis, and irreversible damage of glial cells from exposure to arachidonic acid in vitro. pHi
1766  1994 Synthesis, platelet anti-aggregating activity and anti-inflammatory activity of a series of beta-aminoxypropionic acids. ADP, MDA, PRP
1767  1994 The cleavage of plasmenylethanolamine by phospholipase A2 appears to be mediated by the low affinity binding site of the TxA2/PGH2 receptor in U46619-stimulated human platelets. ---
1768  1994 The effect of 3-[2-(cyclopropylamino)ethoxy]xanthone on platelet thromboxane formation. ---
1769  1994 The effect of arachidonic acid on the hydroosmotic action of vasopressin in frog urinary bladder. ---
1770  1994 The effect of linoleic, arachidonic and eicosapentaenoic acid supplementation on prostacyclin production in rats. EPA, LA
1771  1994 The effect of oral administration of eicosapentaenoic and docosahexaenoic acids on acute inflammation and fatty acid composition in rats. DHA, EPA
1772  1994 The induction of anterior chamber inflammation by factors released from hydrogen peroxide-injured corneas: effect of dexamethasone and indomethacin. GO, MEM, NCF
1773  1994 The mechanism of arachidonic acid release in collagen-activated human platelets. DG, lysoPA, lysoPI, MG, PA, PI-PLC, TXB2
1774  1994 The position of NO among endogenous vasodilators. GC-MS
1775  1994 The presence of cytoplasmic lipid droplets is not sufficient to account for neutral lipid signals in the 1H MR spectra of neutrophils. LPS, OA
1776  1994 YC-1, a novel activator of platelet guanylate cyclase. PAF
1777  1994 [Biological effects on premature neonates of a milk formula enriched with alpha-linolenic acid: a multicenter study]. ---
1778  1994 [Effect of acetylsalvianolic acid A on platelet function]. ASAA
1779  1994 [Effect of protopine on rabbit platelet function]. Pro, TMVA
1780  1994 [Effect of Y-20811, a thromboxane A2 synthetase inhibitor, on the arachidonic acid-induced response in the blood-superfused canine coronary artery]. ---
1781  1994 [Effects of lanthanum ion on beta-endorphin biosynthesis and release in rat pituitary cells]. DEX
1782  1994 [Inhibitory effects of exogenous eicosapentaenoic acid on generation of leukotriene C4 and leukotriene B4 by human leukocytes stimulated with calcium ionophore]. EPA
1783  1994 [The studies on the mechanism of platelet activation induced by exogenous arachidonic acid with special reference to intraplatelet Ca2+ mobilization]. CTC
1784  1995 1,25-Dihydroxyvitamin D3 or dexamethasone modulate arachidonic acid uptake and distribution into glycerophospholipids by normal adult human osteoblast-like cells. hOB
1785  1995 5-Lipoxygenase products modulate the activity of the 85-kDa phospholipase A2 in human neutrophils. 5-HETE, LTB4, PLA2
1786  1995 A Ca2+/calmodulin kinase inhibitor, KN-62, inhibits neurite outgrowth stimulated by CAMs and FGF. CaM
1787  1995 A study of the novel anti-inflammatory agent florifenine topical anti-inflammatory activity and influence on arachidonic acid metabolism and neutrophil functions. TPA
1788  1995 Acetylated low density lipoprotein inhibits the incorporation of arachidonic acid in phospholipids with a concomitant increase of cholesterol arachidonate in rat peritoneal macrophages. ACAT, CE, LDL, PL
1789  1995 ACTH-dependent proteolytic activity of a novel phosphoprotein (p43) intermediary in the activation of phospholipase A2 and steroidogenesis. ---
1790  1995 Actions of arachidonic acid on erythrocyte membrane Rb permeability. ---
1791  1995 Adenosine triphosphate and arachidonic acid stimulate glycogenolysis in primary cultures of mouse cerebral cortical astrocytes. ATP, VIP
1792  1995 Age-related depletion of linoleic acid desaturation in liver microsomes from young spontaneously hypertensive rats. LA, SHR
1793  1995 Agonist-mediated activation of PLA2 initiates Ca2+ mobilization in intestinal longitudinal smooth muscle. PLA2, PTX
1794  1995 Alpha-linolenic acid in the treatment of rheumatoid arthritis. A double-blind, placebo-controlled and randomized study: flaxseed vs. safflower seed. alpha-LNA, DHA, EPA, LTB4, PGE2
1795  1995 Amphibian oocyte: a model of a possible regulatory mechanism for prostaglandin E2 and prostaglandin F2 alpha synthesis. GnRH, PGE2, PGF2 alpha, SP
1796  1995 Anandamide, an endogenous cannabinomimetic substance, modulates rat brain protein kinase C in vitro. PKC, PS
1797  1995 Antioxidant and cytotoxic tocopheryl quinones in normal and cancer cells. ALL, alpha-T, alpha-TQ, delta-TQ, DOX, gamma-TQ, gammaT, SMC, VLB
1798  1995 Antioxidants, but not cAMP or high K+, prevent arachidonic acid toxicity on neuronal cultures. ---
1799  1995 Arachidonic acid and diacylglycerol release associated with inhibition of myosin light chain dephosphorylation in rabbit smooth muscle. DAG, GC-MS, PDBu, PE
1800  1995 Arachidonic acid and its metabolites effects on testosterone production by rat Leydig cells. IND, LTB4, PGE2
1801  1995 Arachidonic acid and lysophosphatidylcholine modulate excitatory transmitter amino acid release from the rat cerebral cortex. EAAs, PLA2
1802  1995 Arachidonic acid as a neurotoxic and neurotrophic substance. ---
1803  1995 Arachidonic acid disrupts calcium dynamics in neonatal rat cardiac myocytes. ---
1804  1995 Arachidonic acid increases cytosolic calcium and stimulates hormone release in rat lactotrophs. PRL
1805  1995 Arachidonic acid inhibits a purified and reconstituted glutamate transporter directly from the water phase and not via the phospholipid membrane. ---
1806  1995 Arachidonic acid inhibits hCG-stimulated progesterone production by corpora lutea of primates: potential mechanism of action. CL, PDBu, PI, PKC
1807  1995 Arachidonic acid inhibits hormone-stimulated cAMP accumulation in the medullary thick ascending limb of the rat kidney by a mechanism sensitive to pertussis toxin. AVP, BAPTA, cAMP, mTAL, PTX
1808  1995 Arachidonic acid inhibits potassium conductances in cultured rat oligodendrocytes. IKir
1809  1995 Arachidonic acid is a preferred acetyl donor among fatty acids in the acetylation of p-aminobenzoic acid by human lymphoid cells. PA, PABA, PBML
1810  1995 Arachidonic acid is functioning as a second messenger in activating the Ca2+ entry process on H1-histaminoceptor stimulation in DDT1 MF-2 cells. ---
1811  1995 Arachidonic acid may mediate the galanin-induced hyperpolarization in parasympathetic neurons from Necturus maculosus. ---
1812  1995 Arachidonic acid metabolites are involved in mediating red blood cell adherence to endothelium. EC, NDGA, RBCs
1813  1995 Arachidonic acid-dependent phosphorylation of troponin I and myosin light chain 2 in cardiac myocytes. ET, MLC2, PMA, TnI
1814  1995 Arachidonic-acid-activated membrane conductances in dissociated cardiac parasympathetic neurons from Necturus. NDGA, NMG
1815  1995 ATP receptor-mediated increase of Ca ionophore-stimulated arachidonic acid release from PC12 pheochromocytoma cells. ---
1816  1995 Biochemical functions of a pool of arachidonic acid associated with triglycerides in human inflammatory cells. TGs
1817  1995 Blocking effects of polyunsaturated fatty acids on Na+ channels of neonatal rat ventricular myocytes. EPA, PUFAs
1818  1995 Blood cell redox status and fatty acids. GSH-Px
1819  1995 Calcium influx is required for tannin-mediated arachidonic acid release from alveolar macrophages. ---
1820  1995 Cell-based assay for functional screening of compounds active at the human endothelin A receptor. CHO
1821  1995 Characterisation of cytosolic phospholipase A2 as mediator of the enhanced arachidonic acid release from dimethyl sulphoxide differentiated U937 cells. cPLA2, DMSO, PLA2, PMA
1822  1995 Characterization and inhibition of 15-lipoxygenase in human monocytes: comparison with soybean 15-lipoxygenase. 15-LO, HMC, IL-4
1823  1995 Characterization of arachidonic acid metabolism and the polymorphonuclear leukocyte response in mice infected intracorneally with Pseudomonas aeruginosa. MPO
1824  1995 Characterization of zinc uptake and its regulation by arachidonic acid in fetal type II pneumocytes. ---
1825  1995 Clearance and metabolism of arachidonic acid by C6 glioma cells and astrocytes. RIA
1826  1995 Co-existence and interaction between facilitatory and inhibitory metabotropic glutamate receptors and the inhibitory adenosine A1 receptor in cerebrocortical nerve terminals. ACPD, CHA, L-AP4, mGluRs
1827  1995 Competition for factors and cellular resources as a principle of pattern formation in Hydra. I. Increase of the potentials for head and bud formation and rescue of the regeneration-deficient mutant reg-16 by treatment with diacylglycerol and arachidonic acid. DAG, PKC
1828  1995 Complement C5b-9 activates cytosolic phospholipase A2 in glomerular epithelial cells. GEC, PLA2
1829  1995 Concomitant acceleration of the activation and inactivation kinetics of the human delayed rectifier K+ channel (Kv1.1) by Ca(2+)-independent phospholipase A2. PLA2
1830  1995 Conversion of endogenous arachidonic acid to 5,15-diHETE and lipoxins by polymorphonuclear cells from patients with rheumatoid arthritis. LXs, PMN, RA
1831  1995 Curcumin, a major component of food spice turmeric (Curcuma longa) inhibits aggregation and alters eicosanoid metabolism in human blood platelets. TXB2
1832  1995 Cyclosporin A inhibits leukotriene production in intact RBL-1 cells without inhibiting leukotriene biosynthetic enzymes. 5-HETE, CsA, HPLC, RBL-1
1833  1995 Cytochrome P450-dependent effects of bradykinin in the rat heart. BK
1834  1995 Cytosolic phospholipase A2 and cyclooxygenase-2 mediate release and metabolism of arachidonic acid in tumor necrosis factor-alpha-primed cultured intestinal epithelial cells (INT 407). COX, cPLA2, PGE2, PLA2, TNF-alpha
1835  1995 Cytotoxic action of cis-unsaturated fatty acids on human cervical carcinoma (HeLa) cells in vitro. ALA, BHA, BHT, c-UFAs, CPZ, DGLA, FAs, GLA, HeLa, LA, NDGA, PG, SOD, TFP
1836  1995 Development of an in vitro model of essential fatty acid deficiency in fish cells. EFA, EFAD, EPA, EPC, PUFA, TF
1837  1995 Diacylglycerol lipase activation and 5-lipoxygenase activation and translocation following TCR/CD3 triggering in T cells. cLT, DAG, TCR
1838  1995 Diets rich in eicosapentaenoic acid and gamma-linolenic acid affect phospholipid fatty acid composition and production of prostaglandins E1, E2 and E3 in turbot (Scophthalmus maximus), a species deficient in delta 5 fatty acid desaturase. BO, DHGLA, EPA, GLA, MO, PC, PE, PGE1, PI, PUFA
1839  1995 Differences exist in the relationships between dietary linoleic and alpha-linolenic acids and their respective long-chain metabolites. alpha-LA, EPA, LA
1840  1995 Differences in fatty acid composition of immature and mature articular cartilage in humans and sheep. EFA, LA
1841  1995 Different mechanisms of renal Na-K-ATPase regulation by dopamine in the proximal and distal nephron. CCD, DA, MTAL, PCT, PKA, PKC, PLA2
1842  1995 Differential Expression of Platelet Activation Markers CD62P and CD63 Following Stimulation with PAF, Arachidonic Acid and Collagen. PAF
1843  1995 Differential influence of arachidonic vs. eicosapentaenoic acid on experimental pulmonary hypertension. EPA, PAP, TX
1844  1995 Differential utilization of linoleic and arachidonic acid by cultured human keratinocytes. LA
1845  1995 Discrete pathways for arachidonic acid release from tannin versus beta-glucan-stimulated rabbit alveolar macrophages. ---
1846  1995 Distribution of arachidonic, eicosapentaenoic, docosahexaenoic and related fatty acids in ovine endometrial phospholipids in late gestation and labor. dGA, DHA, EPA, GC, LC-PUFA, LPC, PC, PE, PG, PI, PL, PS, TLC, UI
1847  1995 Docosahexaenoic acid is a potent inhibitor of rat uterine stromal cell proliferation. DHA
1848  1995 Dopamine D2 receptors potentiate arachidonate release via activation of cytosolic, arachidonate-specific phospholipase A2. cPLA2
1849  1995 Effect of arachidonic acid on activity of the apical K+ channel in the thick ascending limb of the rat kidney. 17-ODYA, 20-HETE, CDC, DBDD, TAL
1850  1995 Effect of arachidonic acid on Na+/H+ exchange and neutral amino acid transport in sea urchin eggs. ---
1851  1995 Effects of an anti-inflammatory peptide (antiflammin 2) on cell influx, eicosanoid biosynthesis and oedema formation by arachidonic acid and tetradecanoyl phorbol dermal application. LTB4, TPA
1852  1995 Effects of arachidonic acid on dopamine synthesis, spontaneous release, and uptake in striatal synaptosomes from the rat. ---
1853  1995 Effects of dietary borage oil [enriched in gamma-linolenic acid,18:3(n-6)] or marine fish oil [enriched in eicosapentaenoic acid,20:5(n-3)] on growth, mortalities, liver histopathology and lipid composition of juvenile turbot (Scophthalmus maximus). BO, DHGLA, EPA, GLA, MO, PUFA
1854  1995 Effects of dietary fish oil (MaxEPA) on N-nitrosobis(2-oxopropyl)amine (BOP)-induced pancreatic carcinogenesis in hamsters. BLL, BOP, LA, LI, PGs, TX
1855  1995 Effects of fatty acyl coenzyme A esters on lipoxygenase and cyclooxygenase metabolism of arachidonic acid in rabbit platelets. CoA
1856  1995 Effects of Hoe-140 and ramiprilat on arteriolar tone and dilation to bradykinin in skeletal muscle of rats. ACh, ADO, BK
1857  1995 Effects of thromboxane A2 synthase inhibitors (CV-4151 and ozagrel), aspirin, and ticlopidine on the thrombosis caused by endothelial cell injury. TXA2
1858  1995 Effects of variation in oxygen tension on responses of the human fetoplacental vasculature to vasoactive agents in vitro. 5-HT, ATP, BK, FAP
1859  1995 Eicosanoid production and phospholipase A2 activity in uterine tissue from castrated rats with non-insulin dependent diabetes mellitus. LTB4, PGs, PLA2, TXB2
1860  1995 Eicosapentaenoic acid modulates arachidonic acid metabolism in rat alveolar macrophages. EPA, LTB4
1861  1995 Epoxygenase metabolites of docosahexaenoic and eicosapentaenoic acids inhibit platelet aggregation at concentrations below those affecting thromboxane synthesis. DHA, EPA
1862  1995 Essential fatty acid metabolism in patients with essential hypertension, diabetes mellitus and coronary heart disease. ALA, CHD, DGLA, DHA, DM, EFAs, EPA, GLA, HTN, LA, NIDDM, PGE1
1863  1995 Essential fatty acids in full term infants fed breast milk or formula. DHA, LCP
1864  1995 Estimation of arachidonic acid synthesis in full term neonates using natural variation of 13C content. GC-IRMS, LA
1865  1995 Eugenol: a dual inhibitor of platelet-activating factor and arachidonic acid metabolism. PAF
1866  1995 Evidence of a temperature-sensitive step in the release of prostaglandin E2 in calcium ionophore-stimulated rat muscle. PGE2, PGF2 alpha
1867  1995 Exposure to gp120 of HIV-1 induces an increased release of arachidonic acid in rat primary neuronal cell culture followed by NMDA receptor-mediated neurotoxicity. ---
1868  1995 Expression of the proenkephalin A gene and [Met5]-enkephalin secretion induced by arachidonic acid in bovine adrenal medullary chromaffin cells: involvement of second messengers. BAMC, PKC, proENK
1869  1995 Fatty acids in human platelets and plasma. Dietary seal oil decreases sensitivity toward microbubbles. DHA, EPA, PRP
1870  1995 FGF inhibits neurite outgrowth over monolayers of astrocytes and fibroblasts expressing transfected cell adhesion molecules. FGF
1871  1995 Glutathione, glutathione utilizing enzymes and thioltransferase in platelets of insulin-dependent diabetic patients: relation with platelet aggregation and with microangiopatic complications. G6PDH, GSH-Px, GSH-Tr, TT
1872  1995 High-affinity CCK receptors are coupled to phospholipase A2 pathways to mediate pancreatic amylase secretion. CCK, PLA2
1873  1995 HIV-induced TNF-alpha regulates arachidonic acid and PGE2 release from HIV-infected mononuclear phagocytes. MO, p.i
1874  1995 Immortalization of cat iris sphincter smooth muscle cells by SV40 virus: growth, morphological, biochemical and pharmacological characteristics. PG
1875  1995 In vitro influence of polyunsaturated fatty acids on nosocomial Pseudomonas aeruginosa: a preliminary report. GLA, PUFAs
1876  1995 Incorporation of arachidonic and eicosapentaenoic acids into phospholipids of non-transformed and spontaneously-transformed rat liver epithelial cells: effects on DNA-synthesis. EPA, PC, PE, RLEC
1877  1995 Influence of calcium on arachidonic acid mobilization by murine resident peritoneal macrophages. PLA2, PMA
1878  1995 Influence of polyunsaturated fatty acids on lipid metabolism in human blood mononuclear cells and early biochemical events associated with lymphocyte activation. PBMC, PDE
1879  1995 Influx of extracellular calcium and agonist-coupling appear essential for the activation of thromboxane A2-dependent phospholipase A2 in human platelets. COX, PLA2, TXA2
1880  1995 Inhibition of calcium-independent phospholipase A2 prevents arachidonic acid incorporation and phospholipid remodeling in P388D1 macrophages. BEL, PLA2
1881  1995 Inhibition of gonadotropin-stimulated ovarian steroid production by polyunsaturated fatty acids in teleost fish. DHA, PUFAs
1882  1995 Inhibition of leukotriene production by FK506 in rat basophilic leukemia-1 cells. 5-HETE, LTB4, LTs
1883  1995 Inhibition of the human platelet cyclooxygenase response by the naturally occurring phenazine derivative, 1-hydroxyphenazine. 12-HETE, HHT, TXB2
1884  1995 Interactions between large and small luteal cells collected during the mid- or late-luteal stages of the bovine oestrous cycle. LH
1885  1995 Interleukin-11 induces phosphatidic acid formation and activates MAP kinase in mouse 3T3-L1 cells. IL-11, MoAb, PA, PAP, PLD
1886  1995 Ligands of purinergic receptors stimulate electrogenic H(+)-transport of neutrophils. ---
1887  1995 Lower leukotriene C(4) levels in bronchoalveolar lavage fluid of asthmatic subjects after 2.5 years of inhaled corticosteroid therapy. BAL, LT, PG
1888  1995 Mechanisms of action of the tumor necrosis factor and lymphotoxin ligand-receptor system. DAG, LT, LTbetaR, PC-PLC, PKC, PLA2, SM, SMase, TNF
1889  1995 Migration of human inflammatory cells into the lung results in the remodeling of arachidonic acid into a triglyceride pool. BAL, TG
1890  1995 Milk composition in women from five different regions of China: the great diversity of milk fatty acids. DHA
1891  1995 Model experiments on squid axons and NG108-15 mouse neuroblastoma x rat glioma hybrid cells. Ca, ETYA, HVA, LVA, PDB, PKC
1892  1995 Modulation by nitric oxide of prostaglandin biosynthesis in the rat. 6-keto-PGF1 alpha, COX, NO, SNAP, SNP
1893  1995 Modulation of calcium channel currents by arachidonic acid in single smooth muscle cells from vas deferens of the guinea-pig. GTP, INDO, NDGA, PGF2 alpha
1894  1995 Modulation of neuronal calcium channels by arachidonic acid and related substances. HVA, LVA
1895  1995 Modulation of NMDA receptor-mediated release of [3H]arachidonate in hippocampal slices of immature rats. NMDA, PND
1896  1995 Modulation of superoxide generation in in vivo lipopolysaccharide-primed rat alveolar macrophages by arachidonic acid and inhibitors of protein kinase C, phospholipase A2, protein serine-threonine phosphatase(s), protein tyrosine kinase(s) and phosphatase(s). 5-LO, CO, LPS, PKC, PLA2, PMA, PSP, PTK, PTP, SAL
1897  1995 Mouse spermatozoa can synthesize PGE2 and 5-HETE in vitro: stimulatory action of nitric oxide. 5-HETE, Hb, NO, NP, PGs
1898  1995 Neutrophil release of arachidonic acid, oxidants, and proteinases: causally related or independent. fMLP, LZ, MPO, PMN
1899  1995 New indole and pyridazinoindole analogs--synthesis and study as inhibitors of phosphodiesterases and as inhibitors of blood platelet aggregation. ---
1900  1995 Noradrenaline and dopamine infusions modulate arachidonic acid cyclooxygenase and 5-lipoxygenase pathways ex vivo in man. PGE2, TX/LT
1901  1995 Omega-3 fatty acids suppress the enhanced production of 5-lipoxygenase products from polymorph neutrophil granulocytes in cystic fibrosis. EPA, PMN
1902  1995 Ozone exposure of human tracheal epithelial cells inactivates cyclooxygenase and increases 15-HETE production. 15-HETE, CO, PGE2, TE, TLC
1903  1995 PKC zeta is a molecular switch in signal transduction of TNF-alpha, bifunctionally regulated by ceramide and arachidonic acid. ---
1904  1995 Platelet Aggregometry - Dose-related Responses to Arachidonic Acid in Childhood Nephrotic Syndrome. ---
1905  1995 Platelet-activating factor preferentially stimulates the phospholipase A2/cyclooxygenase cascade in the rabbit cornea. DAG, HPLC, PA, PAF, PC, PE, PI, PIP, TLC
1906  1995 Platelet-activating factor stimulates eicosanoid production in cultured feline tracheal epithelial cells. Ca-ionophore, HETE, HPLC, PAF, PG, RIA, TXB2
1907  1995 Polyunsaturated fatty acid enrichment increases ultraviolet A-induced lipid peroxidation in NCTC 2544 human keratinocytes. TBARS
1908  1995 Possible sites of dopaminergic inhibition of gonadotropin release from the pituitary of a teleost fish, tilapia. APO, BRCR, DA, PKC
1909  1995 Potent antiplatelet, anti-inflammatory and antiallergic isoflavanquinones from the roots of Abrus precatorius. ---
1910  1995 Proposed signaling role of arachidonic acid in human myometrium. HMC, PE
1911  1995 Prostaglandin H synthetase-mediated metabolism of dopamine: implication for Parkinson's disease. PHS
1912  1995 Prostaglandin metabolism during growth and differentiation of the regenerating vertebrate appendage. cAMP, FA, PGs
1913  1995 Protein kinase C activation precedes arachidonic acid release during IgG-mediated phagocytosis. PKC
1914  1995 Protein kinases and prostaglandin production in ovine astroglia. COX, IL-1alpha, PGF2 alpha, PKC, PLA2
1915  1995 Quantitative chromatographic analysis of inositol phospholipids and related compounds. DAG, IPs
1916  1995 Radiodetoxified endotoxin-induced tolerance. Effect on endotoxin lethality and macrophage arachidonic acid metabolism. RD
1917  1995 Regulation of bradykinin-stimulated phospholipase C and arachidonic acid release by protein kinase A in MDCK-D1 cells. AVP, BDK, DAG, FSK, IBMX, InsP, PKA, PKC, PLC, SSP, TPA
1918  1995 Regulation of endometrial prostaglandin synthesis during early pregnancy in cattle: effects of phospholipases and calcium in vitro. PLA2
1919  1995 Regulation of free arachidonic acid levels in isolated salivary glands from the lone star tick: a role for dopamine. arachidonyl-PL, LAT, PLA2
1920  1995 Regulation of phosphatidylinositol kinases by arachidonic acid in rat submandibular gland cells. ATP, PI
1921  1995 Reorientation of macrophage mediator production in endotoxin tolerance. 6-keto-PGF1 alpha, Gi, IL-6, NO, PT
1922  1995 Role of cytochrome P-450 enzymes and metabolites of arachidonic acid in the control of vascular tone. EETs, HETEs
1923  1995 Role of cytosolic phospholipase A2 in arachidonic acid release of rat-liver macrophages: regulation by Ca2+ and phosphorylation. cPLA2, LPS, MAP, PMA
1924  1995 Role of hydroxyl radical in the stimulation of arachidonic acid release caused by H2O2 in pulmonary smooth muscle cells: protective effect of anion channel blocker. DFO, DMTU
1925  1995 Role of interferon-alpha in arachidonic acid metabolism by the rat uteri from spayed animals: effect of 17 beta-estradiol. 5-HETE, IFN, PG, TXB2
1926  1995 Role of intracellular calcium in the regulation of phospholipase A2 in fMet-Leu-Phe-challenged human polymorph neutrophils. cPLA2, PKC, PMN
1927  1995 Roles of arachidonic acid, lipoxygenases and phosphatases in calcium-dependent modulation of M-current in bullfrog sympathetic neurons. 15-HETE, 4-BPB, ETI, LHRH, LO, NDGA
1928  1995 Roles of prostaglandin production and mitogen-activated protein kinase activation in hepatocyte growth factor-mediated rat hepatocyte proliferation. cPLA2, EGF, HGF, MAP, PGE1
1929  1995 Saiboku-To, a herbal extract mixture, selectively inhibits 5-lipoxygenase activity in leukotriene synthesis in rat basophilic leukemia-1 cells. 5-LO, cLTs, LTB4, TXA2
1930  1995 SB 203347, an inhibitor of 14 kDa phospholipase A2, alters human neutrophil arachidonic acid release and metabolism and prolongs survival in murine endotoxin shock. PLA2
1931  1995 Sickle cell vaso-occlusive crisis is associated with abnormalities in the ratio of vasoconstrictor to vasodilator prostanoids. 6-k-PGF1 alpha, SCD, TX, VOC
1932  1995 Suppression of evoked IPSPs by arachidonic acid and prostaglandin F2 alpha. ---
1933  1995 Synthesis, antiinflammatory activity and platelet antiaggregating activity of a new series of beta-aminoxypropionic acids. ADP, AOPAs, ArAAs, MDA, PRP, SAOPAs
1934  1995 The negative coupling between serotonin and muscarinic receptor(s) for arachidonic acid and inositol phosphates release in brain cortex synaptoneurosomes. Effect of aging. IPs, mAChR
1935  1995 The regulation of arachidonate lipoxygenase metabolite formation in cells derived from intrauterine tissues. 5-HETE, LTB4
1936  1995 Time course and concentration dependence of the incorporation of deuterated/tritiated arachidonic acid and derived fatty acids in THP-1 cell lipids. FA, PC, PL, TG
1937  1995 Transcriptional induction of prostaglandin G/H synthase-2 by basic fibroblast growth factor. bFGF, PGHS-2
1938  1995 [Ca2+] modulates the ratio between cycloxygenase and lipoxygenase metabolism of arachidonic acid in homogenates of hippocampal astroglial cultures. 12-HETE, 12-HHT, COX, LOX, PG
1939  1995 [Effects of berberine on platelet aggregation and plasma levels of TXB2 and 6-keto-PGF1 alpha in rats with reversible middle cerebral artery occlusion]. 6-keto-PGF1 alpha, Ber, Coll, MCAO, TXB2
1940  1995 [Effects of selenium and vitamin E on arachidonic acid metabolism in experimental myocardial ischaemia]. CAT, CK, CuZnSOD, GSH-PO, LDH, LPO, LTC4, PC, PLA2, Se, TXA2, VE
1941  1995 [Is a fish oil enriched diet therapeutically beneficial?]. ---
1942  1995 [Pharmacological profile of F-0401, a novel dihydropyridine derivative. III. The anti-aggregatory action of F-0401 on rabbit platelets]. PAF, TXA2
1943  1995 [Treatment of chronic virus hepatitis with acetylsalicylic acid]. ASA, IFN, IFN
1944  1996 2-Arylmethyl-1,4-benzoquinones. I. Novel inhibitors of platelet aggregation: synthesis and pharmacological evaluation. ---
1945  1996 5-Hydroxyeicosatetraenoic acid and human parturition. 5-HETE, ASA
1946  1996 5-Lipoxygenase metabolism in alveolar macrophages from subjects infected with the human immunodeficiency virus. 5-LO, AM, LT
1947  1996 A comparative study of arachidonic acid metabolism in rabbit cultured astrocytes and human astrocytoma cells (1321N1). BK, PG, PL, TX
1948  1996 A new breast milk supplement for preterm infants. DHA, EBM, LC-PUFA
1949  1996 Abnormal incorporation of arachidonic acid into platelets of drug-free patients with schizophrenia. DAG, HETE
1950  1996 Acrosome reaction stimulated by the GTP non-hydrolizable analogue GTP gamma S is blocked by phospholipase A2 inhibitors in human spermatozoa. LPC
1951  1996 Activation of phospholipase C-gamma by the concerted action of tau proteins and arachidonic acid. PLCgamma
1952  1996 Activation of serotonergic 5-HT1A receptor reduces Ca(2+)- and glutamatergic receptor-evoked arachidonic acid and No/cGMP release in adult hippocampus. NO
1953  1996 Acute hypoxia modulates arachidonic acid metabolism in cat carotid bodies. Role of dopamine. CB, DA, PtdIns
1954  1996 Afferent arteriolar response to arachidonic acid: involvement of metabolic pathways. CHAPS
1955  1996 Age-related enhancement of 5-lipoxygenase metabolic capacity in cattle alveolar macrophages. 5-HETE, 5-LO, AM, LT
1956  1996 Airway hyperresponsiveness to acetylcholine induced by aerosolized arachidonic acid metabolites in guinea-pigs. ACh, LT, PG, TX
1957  1996 alpha-1-Adrenergic receptor stimulation causes arachidonic acid release through pertussis toxin-sensitive GTP-binding protein and JNK activation in rabbit aortic smooth muscle cells. AR, G proteins, IAP, JNK, MAP, PI, PLA2, PT, SMC
1958  1996 Alterations in arachidonic acid metabolism in mouse mast cells induced to undergo maturation in vitro in response to stem cell factor. BMCMCs, PL, SCF
1959  1996 Antagonistic effects of dietary arachidonic acid and n-3 polyunsaturated fatty acids. PUFA
1960  1996 Antiplatelet and calcium inhibitory properties of eugenol and sodium eugenol acetate. ---
1961  1996 Antiplatelet and vasorelaxing actions of some aporphinoids. ADP, PAF
1962  1996 Antiplatelet effect of a new inhibitor of thromboxane synthase and thromboxane A2 receptors. ASA, NSAIDs, PAF, TXB2
1963  1996 Antithrombotic effect of GYKI-14766 in a canine model of arterial and venous rethrombosis: a comparison with heparin. APTT, i.v
1964  1996 Arachidonate lipoxygenases as essential regulators of cell survival and apoptosis. COX, LOX
1965  1996 Arachidonate metabolism in human placenta, fetal membranes, decidua and myometrium: lipoxygenase and cytochrome P450 metabolites as main products in HPLC profiles. 12-HETE, HPLC
1966  1996 Arachidonic acid and lipoxygenase products stimulate protein kinase C beta mRNA levels in pituitary alpha T3-1 cell line: role in gonadotropin-releasing hormone action. 5-HETE, GnRH, LTC4, PKCbeta
1967  1996 Arachidonic acid increases activation of NADPH oxidase in monocytic U937 cells by accelerated translocation of p47-phox and co-stimulation of protein kinase C. IFN-gamma, NADPH, PKC, PMA
1968  1996 Arachidonic acid inhibits activity of cloned renal K+ channel, ROMK1. ---
1969  1996 Arachidonic acid regulation of vasopressin release and intracellular Ca2+ in neurohypophysial nerve endings. ---
1970  1996 Arachidonic acid status of human infants: influence of gestational age at birth and diets with very long chain n-3 and n-6 fatty acids. DHA, EPA
1971  1996 Arachidonic acid supply and metabolism in human infants born at full term. DHA
1972  1996 Arachidonic acid synthesis and lipid metabolism in retinoic acid-differentiated neuroblastoma cells. LA, PL, PUFA
1973  1996 Arachidonic acid to eicosapentaenoic acid ratio in blood correlates positively with clinical symptoms of depression. EPA, HRS, LRS, PL, PUFA
1974  1996 Arachidonic acid-induced down-regulation of protein kinase C delta in beta-cells. PKC
1975  1996 Arachidonic acid-induced hormone release in somatotropes: involvement of calcium. 5-, 12- and 15-HpETE, PKC
1976  1996 Artificial rearing of infant rats on milk formula deficient in n-3 essential fatty acids: a rapid method for the production of experimental n-3 deficiency. CNS, DHA, PUFA
1977  1996 Bile but not chyle lipoprotein is an important source of arachidonic acid for the rat small intestine. ---
1978  1996 Biochemical effects of dietary linoleic/alpha-linolenic acid ratio in term infants. DHA, LNA
1979  1996 Biological effects of dietary arachidonic acid. Introduction. PUFA
1980  1996 Blood pressure, serum lipids, and fatty acids in populations on a lake-fish diet or on a vegetarian diet in Tanzania. DHA, EPA, FA, FD, TC, TG, VD
1981  1996 Caerulein-stimulated arachidonic acid release in rat pancreatic acini: a diacylglycerol lipase affair. DAG, PLA2, PLC, PLD
1982  1996 Calcium mobilization from the intracellular mitochondrial and nonmitochondrial stores of the rat cerebellum. SPC, Sph
1983  1996 Calcium/calmodulin-dependent protein kinase IIalpha mediates activation of mitogen-activated protein kinase and cytosolic phospholipase A2 in norepinephrine-induced arachidonic acid release in rabbit aortic smooth muscle cells. CaM kinase II, cPLA2, MAP kinase, NE, VSMC
1984  1996 CAM-FGF Receptor Interactions: A Model for Axonal Growth DAG, FGFR
1985  1996 CAM-FGF receptor interactions: a model for axonal growth. DAG, FGFR
1986  1996 Candida albicans induces the release of inflammatory mediators from human peripheral blood monocytes. C. albicans, IL-1 beta, IL-6, IL-8, TNF-alpha
1987  1996 Characterization of a secretory phospholipase A2 in human bronchoalveolar lavage fluid. BALF, PAF, PLA2
1988  1996 Cloned and expressed rat Ca2+-sensing receptor. ---
1989  1996 Colchicine inhibits arachidonate release and 5-lipoxygenase action in alveolar macrophages. 5-LO, AM
1990  1996 Comparison of acceptor and donor substrates in the CoA-independent transacylase reaction in human neutrophils. CoA-IT, PC, PE
1991  1996 Compartmental study of rat renal prostaglandin synthesis during development. COX, PGs
1992  1996 Cord blood neutrophil responses to polyunsaturated fatty acids: effects on degranulation and oxidative respiratory burst. fMLP, PUFA
1993  1996 Curcumin induces apoptosis in immortalized NIH 3T3 and malignant cancer cell lines. PKC
1994  1996 Cytosolic and mitochondrial proteins as possible targets of cycloheximide effect on adrenal steroidogenesis. CHX
1995  1996 Defibrotide mediated inhibition of serotonin, endothelin-I, thromboxane, and serum induced contraction of canine femoral and pulmonary arterial rings. PRP
1996  1996 Developmental changes in arachidonic acid potentiation of NMDA currents in cortical neurones. NMDA
1997  1996 Dietary (n-9) eicosatrienoic acid from a cultured fungus inhibits leukotriene B4 synthesis in rats and the effect is modified by dietary linoleic acid. EFA, EPA, ETrA, LTB4, PEC
1998  1996 Dietary alteration of dihomogamma-linolenic acid/arachidonic acid ratio in a rat 5/6-renal-ablation model. The Nutrition & Kidney Disease Research Group. BO, CO, DGLA, GLA, LA, PUFA, RLD, TXB2
1999  1996 Dietary fish oil (MaxEPA) enhances pancreatic carcinogenesis in azaserine-treated rats. AACNs, HF, LA, LF, PG, TXB2
2000  1996 Differential effects of 1,25-(OH)2D3 on acyl hydrolase and cyclooxygenase activities in interleukin 1 beta-stimulated human synovial fibroblast cultures. COX, IL-1 beta, PGE2
2001  1996 Differential effects of n-6 and n-3 polyunsaturated fatty acids on cell growth and early gene expression in Swiss 3T3 fibroblasts. DHA, EPA, PGE2, PUFAs
2002  1996 Differential effects of snake venom phospholipase A2 neurotoxin (beta-bungarotoxin) and enzyme (Naja naja atra) on protein kinases. beta-BuTX, FFAs, N. n. atra, PKC, PLA2
2003  1996 Differential eudismic ratios in the antagonism of human platelet function by phenoxy- and thiophenoxyacetic acids. CPBA, CPPA, CTBA, CTPA
2004  1996 Differential expression of platelet activation markers in aspirin-sensitive asthmatics and normal subjects. Col, PAF
2005  1996 Differential involvement of calcium channels and protein kinase-C activity in GnRH-induced phospholipase-C, -A2 and -D activation in a gonadotrope cell line (alpha T3-1). IPs, PEt, PKC, PLC
2006  1996 Distinct roles in signal transduction for each of the phospholipase A2 enzymes present in P388D1 macrophages. cPLA2, PLA2s, sPLA2
2007  1996 Docosahexaenoic acid is a major n-3 polyunsaturated fatty acid in bovine retinal microvessels. BRECs, DHA
2008  1996 Docosahexaenoic acid reduces GABA response in substantia nigra neuron of rat. DHA, DPA, GABA, Iasp, Igly, SN
2009  1996 Docosahexaenoic acid therapy in docosahexaenoic acid-deficient patients with disorders of peroxisomal biogenesis. DHA-EE
2010  1996 Docosahexaenoic and arachidonic acid content of serum and red blood cell membrane phospholipids of preterm infants fed breast milk, standard formula or formula supplemented with n-3 and n-6 long-chain polyunsaturated fatty acids. DHA
2011  1996 Dual effects of arachidonic acid on ATP-sensitive K+ current of coronary smooth muscle cells. ATP, ATP, ETYA
2012  1996 Dual regulation of PLA2 and PGI2 production by G proteins in bovine aortic endothelial cells. BAEC, cPLA2, G proteins, PLA2
2013  1996 Effect of angiotensin II on the apical K+ channel in the thick ascending limb of the rat kidney. 17-ODYA, 20-HETE, AII, GC/MS, L-NAME, NO, Po, SNAP, TAL
2014  1996 Effect of arachidonic acid on the L-type calcium current in frog cardiac myocytes. Caly, ETYA, INDO, ISO, MA, MC, NDGA, OA, PKA
2015  1996 Effect of degree of unsaturation in dietary fatty acids on arachidonic acid mobilization by peritoneal macrophages. EPA and DHA
2016  1996 Effect of long-chain n-3 fatty acid supplementation on visual acuity and growth of preterm infants with and without bronchopulmonary dysplasia. BPD, LLA, PC
2017  1996 Effects of dietary gamma-linolenic acid on the tissue phospholipid fatty acid composition and the synthesis of eicosanoids in rats. GLA
2018  1996 Effects of dietary n-3/n-6 and polyunsaturated fatty acid/saturated fatty acid ratios on platelet aggregation and lipid metabolism in rats. DHA, EPA, P/S, PL, TXA2
2019  1996 Effects of endothelin on phospholipases and generation of second messengers in cat iris sphincter and SV-CISM-2 cells. ET-1, PEt, PLA2, PLC, PLD
2020  1996 Effects of endothelin-1 on aggregation of normal and uremic platelets. PRP
2021  1996 Effects of ethanol on the incorporation of free fatty acids into cerebral membrane phospholipids. DHA, EtOH, FA, FFAs, LA, PC, PE, PI, PL, PLA2, PS
2022  1996 Effects of fluticasone propionate on arachidonic acid metabolites in BAL-fluid and methacholine dose-response curves in non-smoking atopic asthmatics. BAL, FP
2023  1996 Effects of granulocyte-macrophage colony-stimulating factor on eicosanoid production by mononuclear phagocytes. AM, GM-CSF, LT, PLA2
2024  1996 Effects of linoleic acid, eicosapentaenoic acid, and docosahexaenoic acid on the growth and metastasis of MM48 mammary tumor transplants in mice. DHA, EPA, LA
2025  1996 Effects of non-steroidal anti-inflammatory drugs on prostaglandin E2 production by cyclooxygenase-2 from endogenous and exogenous arachidonic acid in rat peritoneal macrophages stimulated with lipopolysaccharide. COX-2, LPS, NSAIDs, PGE2
2026  1996 Eicosanoid precursors: potential factors for atherogenesis in diabetic CAPD patients? CAPD, EPA, IDDM, NIDDM
2027  1996 Endothelin-1 increases arachidonic acid release in C6 glioma cells through a potassium-modulated influx of calcium. ET-1, PKC, PLA2
2028  1996 Endothelin-1-evoked arachidonic acid release: a Ca(2+)-dependent pathway. ET, ET-1, HPSMC, MAPTAM, PKC
2029  1996 Epinephrine induces a late thromboxane-dependent platelet shape change and enhances synergistically the shape change induced by other platelet agonists. ADP, PAF, PRP, TX
2030  1996 Essential fatty acids and modern lifestyle: a reappraisal. DGLA, EPA, FO, GLA, HCD, WAD
2031  1996 Estrogen pretreatment increases arachidonic acid release by bradykinin stimulated normal human osteoblast-like cells. hOB
2032  1996 Evidence for the involvement of protein kinase C isoforms in alpha-1 adrenergic activation of phospholipase A2 in FRTL-5 thyroid cells. BAPTA, PKC, PLA2, PLC, PMA, TX, Tx
2033  1996 Fatty acid composition of late embryonic and early postnatal rat brain. DHA, FA, NL, PE, PI, PL, PS
2034  1996 Fatty acid metabolism in phenylketonuria. PKU, PUFA
2035  1996 Fish and healthy pregnancy: more than just a red herring! DHA, EFAs
2036  1996 Fish oil fatty acids and human platelets: dose-dependent decrease in dienoic and increase in trienoic thromboxane generation. DCHA, EPA, TX
2037  1996 Hemoglobin affects lipid peroxidation and prostaglandin E2 formation in rat corticocerebral tissues in vitro. Hb, IN, LOOH, TBARS
2038  1996 Human cytomegalovirus-induced immunosuppression. Relationship to tumor necrosis factor-dependent release of arachidonic acid and prostaglandin E2 in human monocytes. CMV, MO
2039  1996 Human polymorphonuclear leukocytes: effect of chloroquine on aggregation, arachidonic acid liberation and thromboxane B2 generation. CQ, fMLP, PMN, TXB2
2040  1996 Identification and localisation of a type IV cytosolic phospholipase A2 in rat pancreatic beta-cells. PLA2
2041  1996 Identification and localization of an actin-binding motif that is unique to the epsilon isoform of protein kinase C and participates in the regulation of synaptic function. PKC
2042  1996 Identification of a putative microvascular oxygen sensor. 17-ODYA
2043  1996 Immunoglobulins from Graves' disease patients stimulate phospholipase A2 and C systems in FRTL-5 and human thyroid cells. IgG, PLA2
2044  1996 Immunosuppressive effects of hypericin on stimulated human leukocytes: inhibition of the arachidonic acid release, leukotriene B(4) and Interleukin-Ialpha production, and activation of nitric oxide formation. NO
2045  1996 Incorporation of 3H-arachidonic acid into platelet phospholipids of patients with schizophrenia. DAG, HD, PA, PC, PE, PI, PLC, PS
2046  1996 Increased synthesis of specific eicosanoids in rejected corneal grafts. PG, PGE2
2047  1996 Inhibition by acetylsalicylic acid, a cyclo-oxygenase inhibitor, and p-bromophenacylbromide, a phospholipase A2 inhibitor, of both cirrhosis and enzyme-altered nodules caused by a choline-deficient, L-amino acid-defined diet in rats. ASA, BPB, CDAA, GST-P, NDGA, QU, TBARS
2048  1996 Inhibition of arachidonic acid induced-aggregation of rabbit platelets with CV-4151 (isbogrel), a selective thromboxane A2 (TXA2) synthase inhibitor: modulation of the antiplatelet action and prostanoid metabolism by rat aortic rings. TXA2
2049  1996 Inhibition of brain P-450 arachidonic acid epoxygenase decreases baseline cerebral blood flow. CBF, EETs, LDF
2050  1996 Inhibition of cytochrome P-450 attenuates hypoxemia of acute lung injury in dogs. ALI, ECV, EET, EVLW
2051  1996 Inhibition of leukotriene synthesis by honokiol in rat basophilic leukemia cells. LT, RBL, RIA
2052  1996 Inhibition of platelet function by A02131-1, a novel inhibitor of cGMP-specific phosphodiesterase, in vitro and in vivo. ADP, ATP, PAF, PDE, PGD2, PGE1, TXB2
2053  1996 Inotropic, chronotropic, and radioligand binding characteristics of leukotriene B4 in cardiac myocyte, papillary muscle, and membrane preparations. EPA
2054  1996 Interaction of nitric oxide synthase inhibitors and their D-enantiomers with rat neutrophil luminol dependent chemiluminescence response. fMLP, L-NAME, L-NMMA, LCL, LUCDCL, PMNLs
2055  1996 Interactions between signaling pathways in mediating GnRH-stimulated GTH release from goldfish pituitary cells: protein kinase C, but not cyclic AMP is an important mediator of GnRH-stimulated gonadotropin secretion in goldfish. cAMP, GnRH, PKA, PKC, TPA
2056  1996 Interleukin-4 inhibits prostaglandin G/H synthase-2 and cytosolic phospholipase A2 induction in neonatal mouse parietal bone cultures. cPLA2, IL-4, PG, PGE2, PGHS-2, PTH, TNF-alpha
2057  1996 Intracellular control of IP3-independent Ca2+ oscillations in pancreatic acini. CCK, ER, PLA2
2058  1996 Intratracheal administration of DBcAMP attenuates edema formation in phosgene-induced acute lung injury. cAMP, dbcAMP, LT, LWG
2059  1996 Involvement of phospholipase A2 and arachidonic acid in cholecystokinin-8-induced insulin secretion in rat islets. ACA, CCK, PKC, PLA2, PLC
2060  1996 Involvement of the 12-lipoxygenase pathway of arachidonic acid metabolism in homosynaptic long-term depression of the rat hippocampus. LTD, LTP, NDGA, PLA2
2061  1996 Lipoxygenase activity in heart cells. 12-HETE, AS, LOX
2062  1996 Long-chain polyunsaturated fatty acid content in Dutch preterm breast milk; differences in the concentrations of docosahexaenoic acid and arachidonic acid due to length of gestation. DHA, LCP
2063  1996 Lung cancer cell lines inhibit leukotriene B4 production by human polymorphonuclear leukocytes at the level of phospholipase A2. 12-HETE, 5-HETE, LTB4, PLA2, PMN
2064  1996 Mechanisms of action of free arachidonic acid on ovarian steroid production in the goldfish. hCG, PGE2
2065  1996 Mechanisms of prostanoid synthesis in human synovial cells: cytokine-peptide synergism. BK, IL-1
2066  1996 Metabolism of gammalinolenic acid in human neutrophils. 15-HETre, DGLA, GLA, LTB4
2067  1996 Microsomal cytochrome P450 peroxygenase metabolism of arachidonic acid in guinea pig liver. CuOOH
2068  1996 Missing links: Cytochrome P450 arachidonate products A new class of lipid mediators. ---
2069  1996 Mitogen-activated protein kinase activation in hepatocyte growth factor-stimulated rat hepatocytes: involvement of protein tyrosine kinase and protein kinase C. GTP, HGF, MAP, PG, PKC, PLA2, PMA, PTK
2070  1996 Modulation by atrial natriuretic factor of receptor-mediated cyclic AMP-dependent responses in canine pulmonary artery during heart failure. ANF, CHF, ISO, PA
2071  1996 Modulation of beta-adrenergic receptor-stimulated lipolysis in the heart by prostaglandins. 6-keto-PGF1 alpha, ISOP, PGE2, PGI2
2072  1996 Modulation of human muscle sodium channels by intracellular fatty acids is dependent on the channel isoform. FFAs
2073  1996 Modulation of N-methyl-D-aspartate receptor mediated arachidonic acid release by endogenous nitric oxide in cultured neurons. AMPA, L-NOArg, NMDA, NO
2074  1996 Modulation of platelet function and vascular smooth muscle contractile actions by a novel, selective, highly potent 5-HT2 antagonist (SR46349). PRP
2075  1996 Modulation of presynaptic calcium homeostasis by nitric oxide. NO
2076  1996 Modulation of ryanodine binding to the cardiac Ca2+ release channel by arachidonic acid. jSR
2077  1996 Modulatory effects of arachidonic acid on the delayed rectifier K+ current in rat pulmonary arterial myocytes. Structural aspects and involvement of protein kinase C. PKC
2078  1996 Molecular characterization of an arachidonic acid epoxygenase in rat brain astrocytes. EETs
2079  1996 Neutrophil activation by anti-proteinase 3 antibodies in Wegener's granulomatosis: role of exogenous arachidonic acid and leukotriene B4 generation. ANCA, LT, PR3, WG
2080  1996 NMDA receptors play an anti-aggregating role in human platelets. ADP, NMDA, PAF, TFP
2081  1996 Novel antiplatelet constituents from formosan moraceous plants. ---
2082  1996 Phospholipase A2 activating protein and idiopathic inflammatory bowel disease. DSS, IBD, LPS, PLA2
2083  1996 Phospholipase activation and secretion: evidence that PLA2, PLC, and PLD are not essential to exocytosis. PA, PKC, PLD, PMA
2084  1996 Phospholipases: in search of a genetic base of schizophrenia. ---
2085  1996 Plasma values of polyunsaturated fatty acids in extremely low birth weight (ELBW) infants fed breast milk or formula very early in life. DHA, ELBW
2086  1996 Platelet and aorta arachidonic and eicosapentaenoic acid levels and in vitro eicosanoid production in rats fed high-fat diets. DHA, EPA, PL, PUFA, TXA2
2087  1996 Possible role of arachidonic acid in stress-induced cytochrome P450IA1 activity. CYPIA1
2088  1996 Products of ozonized arachidonic acid potentiate the formation of DNA single strand breaks in cultured human lung cells. SSB
2089  1996 Proliferation-dependent changes in arachidonic acid mobilization from phospholipids of 3T6 fibroblasts. ---
2090  1996 Prostaglandin F2 alpha and its analogs induce release of endogenous prostaglandins in iris and ciliary muscles isolated from cat and other mammalian species. INDO, IOP, PGF2 alpha
2091  1996 Pyrimidinoceptor-mediated activation of phospholipase C and phospholipase A2 in RAW 264.7 macrophages. IP, PLA2, PLC, PMA, PTX
2092  1996 Rapid modulation of lung and liver macrophage phospholipid fatty acids in endotoxemic rats by continuous enteral feeding with n-3 and gamma-linolenic fatty acids. DHGLA, EPA, GLA, KE, LA
2093  1996 Regulation of GLUT4 gene expression by arachidonic acid. Evidence for multiple pathways, one of which requires oxidation to prostaglandin E2. PPARs, PPRE
2094  1996 Regulation of intracellular magnesium in ascites cells: involvement of different regulatory pathways. EATC, PLA2
2095  1996 Regulation of intracellular pH by phospholipase A2 and protein kinase C upon neutrophil adhesion to solid substrata. ---
2096  1996 Regulation of the adhesion of a human breast carcinoma cell line to type IV collagen and vitronectin: roles for lipoxygenase and protein kinase C. PKC, TPA
2097  1996 Relationship between dietary supply of long-chain fatty acids and membrane composition of long- and very long chain essential fatty acids in developing rat photoreceptors. DHA, PC, PE, ROS
2098  1996 Relative activities of retrovirally expressed murine prostaglandin synthase-1 and -2 depend on source of arachidonic acid. PGE2, PGHS-1 or -2
2099  1996 Role of arachidonic acid and calmodulin in mediating dopamine D1- and GnRH-stimulated growth hormone release in goldfish pituitary cells. BPB, CaM, GH, GnRH, NDGA, PKC, TPA
2100  1996 Role of kinases and G-proteins on arachidonate release induced by zymosan in mouse peritoneal macrophages. PLC
2101  1996 Role of leukotriene C4 in follicle-stimulating hormone (FSH) secretion in female rat pituitary. FSH, GnRH
2102  1996 Role of PLA2, PLC, and PLD in bradykinin-induced release of arachidonic acid in MDCK cells. BK, cPLA2, EtOH, MDCK, PA, PC-PLC, PLD
2103  1996 Role of protein kinase C alpha in nerve growth factor-induced arachidonic acid release from PC12 cells. NGF, PKC, PMA
2104  1996 Secretory phospholipase A2 activity is elevated in bronchoalveolar lavage fluid after ovalbumin sensitization of guinea pigs. AM, cPLA2
2105  1996 Selective neurotoxicity induced by the ionophore lasalocid in rat dissociated cerebral cultures, involvement of the NMDA receptor/channel. CNQX, EAA, LDH, NMDA, PLA2
2106  1996 Selective suppression of endothelial cell activation by arachidonic acid. EC, ICAM, IL, MCP-1, PAI-1, TF, VCAM
2107  1996 Short-term diets rich in arachidonic acid influence plasma phospholipid polyunsaturated fatty acid levels and prostacyclin and thromboxane production in humans. DHA, EPA, n-3 LCP, PL
2108  1996 Sickle red blood cells stimulate endothelial cell production of eicosanoids and diacylglycerol. 15-HETE, DAG, RBCs
2109  1996 Some evidence against the involvement of arachidonic acid in muscarinic suppression of voltage-gated calcium channel current in guinea-pig ileal smooth muscle cells. CCh
2110  1996 Spontaneously hypertensive rats: eicosa-8,11,14-trienoic acid metabolism and arachidonic acid biosynthesis. LCFA, PUFA, SHR
2111  1996 Stimulation of arachidonic acid mobilization by adherence of resident peritoneal macrophages to plastic substrate. ---
2112  1996 Supplementation with an algae source of docosahexaenoic acid increases (n-3) fatty acid status and alters selected risk factors for heart disease in vegetarian subjects. DHA, DHA group, EPA
2113  1996 Swelling, intracellular acidosis, and damage of glial cells. ---
2114  1996 Synergistic effect of interleukin-1 beta and tumor necrosis factor alpha on PGE2 production by articular chondrocytes does not involve PLA2 stimulation. COX, cPLA2, IL-1, PGE2, RAC, sPLA2, TNF
2115  1996 Synthesis and evaluation of coumarin alpha-methylene-gamma-butyrolactones: a new class of platelet aggregation inhibitors. Col, PAF, Thr
2116  1996 Tannin stimulates arachidonic acid release from bovine tracheal epithelial cells. BTE, CBE, ETYA, PLC
2117  1996 The adenovirus E3-14.7K protein and the E3-10.4K/14.5K complex of proteins, which independently inhibit tumor necrosis factor (TNF)-induced apoptosis, also independently inhibit TNF-induced release of arachidonic acid. Ad, cPLA2, TNF
2118  1996 The effect of aqueous garlic extract on the levels of arachidonic acid metabolites (leukotriene C4 and prostaglandin E2) in rat forebrain after ischemia-reperfusion injury. AGE, LTC4, PGE2
2119  1996 The effect of essential fatty acids on growth and urokinase-type plasminogen activator production in human prostate DU-145 cells. ALA, EFA, EPA, GLA, LA, OA, uPA
2120  1996 The effects of omega-3 polyunsaturated (correction of polyunsatulated) fatty acids on the recovery of cardiac function following cold preservation and reperfusion in hyperlipidemic rats. DHA, EPA, HC, P/R
2121  1996 The inhibitory effect of 2-thienyl 2'-hydroxyphenyl ketone (C85) on platelet thromboxane formation. PAF, PGE2, PGH2, PRP, TXB2
2122  1996 The nutritional effect of a-linolenic acid-rich emulsion with total parenteral nutrition in a rat model with inflammatory bowel disease. EPA, FF, IBD, POE, SOE, TPN
2123  1996 The relationships between dietary alpha-linolenic:linoleic acid and rat platelet eicosapentaenoic and arachidonic acids. ALA, EPA
2124  1996 The role of specific eicosanoids in mediating the acute narcotic effects of ethanol. PES, PGE
2125  1996 The role of thromboxane A2 in increased whole blood platelet aggregation in oral contraceptive users. EE
2126  1996 Translocation of cytosolic phospholipase A2 to the nuclear envelope elicits topographically localized phospholipid hydrolysis. cPLA2