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Abbreviation : ERS
Long Form : endoplasmic reticulum stress
No. Year Title Co-occurring Abbreviation
2007 Glial cell-derived neurotrophic factor protects against proteasome inhibition-induced dopamine neuron degeneration by suppression of endoplasmic reticulum stress and caspase-3 activation. DA, GDNF, PD, UPS, VM
2007 Involvement of endoplasmic reticulum stress in myocardial apoptosis of streptozocin-induced diabetic rats. GRP78, STZ
2008 COX-2 inhibition is neither necessary nor sufficient for celecoxib to suppress tumor cell proliferation and focus formation in vitro. DMC, UMC
2008 Endoplasmic reticulum stress contributes to the cell death induced by UCH-L1 inhibitor. PD, UPR, UPS
2008 Endoplasmic reticulum stress is involved in myocardial apoptosis of streptozocin-induced diabetic rats. CHOP, STZ
2009 Cholesterol overloading leads to hepatic L02 cell damage through activation of the unfolded protein response. ACAT, LDL, RT-PCR, UPR
2009 Endoplasmic reticulum stress and autophagy as targets for cancer therapy. ---
2009 Endoplasmic reticulum stress-mediated apoptosis is activated in vascular calcification. RC, VC
2009 Implications of endoplasmic reticulum stress, the unfolded protein response and apoptosis for molecular cancer therapy. Part I: targeting p53, Mdm2, GADD153/CHOP, GRP78/BiP and heat shock proteins. UPR
10  2009 Implications of endoplasmic reticulum stress, the unfolded protein response and apoptosis for molecular cancer therapy. Part II: targeting cell cycle events, caspases, NF-kappaB and the proteasome. UPR
11  2009 Inhibition of endoplasm reticulum stress by ghrelin protects against ischemia/reperfusion injury in rat heart. CHOP, GRP78
12  2009 The HIV protease inhibitor saquinavir induces endoplasmic reticulum stress, autophagy, and apoptosis in ovarian cancer cells. TEM
13  2009 [C/EBP homologous protein-mediated endoplasmic reticulum stress-related apoptosis pathway is involved in abdominal aortic constriction-induced myocardium hypertrophy in rats.]. CHOP, CRT, GRP78, HW/BW, LVW/BW
14  2009 [Effects of edaravone on IRE1 mRNA expression and neuronal apoptosis in the hippocampus of rats with status convulsivus]. SC, SD, TUNEL
15  2009 [Effects of sarcoplasmic reticulum calcium ATPase 2a overexpression on endoplasmic reticulum stress in cardiomyocytes]. CHOP, GRP78, rAd-SERCA2a, SERCA2a
16  2010 14-3-3 protein protects against cardiac endoplasmic reticulum stress (ERS) and ERS-initiated apoptosis in experimental diabetes. CHOP, DN, GRP, IRE, STZ, TNFR
17  2010 Endoplasmic reticulum stress in murine liver and kidney exposed to microcystin-LR. Bcl-2, CHOP, MC-LR
18  2010 Endoplasmic reticulum stress induced by tunicamycin and antagonistic effect of Tiantai No.1 (1) on mesenchymal stem cells. AD, ER, MSCs, TM
19  2010 Endoplasmic reticulum stress-mediated apoptosis involved in indirect recognition pathway blockade induces long-term heart allograft survival. ---
20  2010 Impaired autophagy in sporadic inclusion-body myositis and in endoplasmic reticulum stress-provoked cultured human muscle fibers. sIBM
21  2010 Partial inactivation of cardiac 14-3-3 protein in vivo elicits endoplasmic reticulum stress (ERS) and activates ERS-initiated apoptosis in ERS-induced mice. CHOP, DN, GRP, IRE, Tg, TNFR
22  2010 [Oxidized low density lipoprotein induces macrophage endoplasmic reticulum stress via CD36.]. GRP94, oxLDL, p-IRE1, TM, XBP1
23  2011 Celecoxib induces cell apoptosis coupled with up-regulation of the expression of VEGF by a mechanism involving ER stress in human colorectal cancer cells. ---
24  2011 Cellular prion protein (PrP(C)) and superoxide dismutase (SOD) in vascular cells under oxidative stress. SOD
25  2011 Effect of sulfur dioxide preconditioning on rat myocardial ischemia/reperfusion injury by inducing endoplasmic reticulum stress. GRP78, I/R, p-eIF2alpha
26  2011 Enhancement of photodynamic therapy by 2,5-dimethyl celecoxib, a non-cyclooxygenase-2 inhibitor analog of celecoxib. COX-2, DMC, PDT
27  2011 Estrogen induces apoptosis in estrogen deprivation-resistant breast cancer through stress responses as identified by global gene expression across time. BIM, CASP4
28  2011 Hydrogen sulfide regulates vascular endoplasmic reticulum stress in apolipoprotein E knockout mice. GRP78, HDL, LDL, MnSOD, ROS, TC, TG
29  2011 Inhibition of endoplasm reticulum stress by anisodamine protects against myocardial injury after cardiac arrest and resuscitation in rats. CA, I/R, ROSC
30  2011 Involvement of endoplasmic reticulum stress in adenosine-induced human hepatoma HepG2 cell apoptosis. ---
31  2011 Involvement of endoplasmic reticulum stress-associated apoptosis in a heart failure model induced by chronic myocardial ischemia. CHOP, CMI, GRP78, HF, JNK1
32  2011 Overexpression of p18INK⁴C in LLC-PK1 cells increases resistance to cisplatin-induced apoptosis. AKI, CDKI
33  2011 Sex differences play a role in cardiac endoplasmic reticulum stress (ERS) and ERS-initiated apoptosis induced by pressure overload and thapsigargin. CHOP, GRP, IRE, Thap, TRAF
34  2011 TRB3 overexpression due to endoplasmic reticulum stress inhibits AKT kinase activation of tongue squamous cell carcinoma. OTSCC, p-AKT, shRNA, TG, Tu
35  2011 [Attenuation and mechanism of endoplasmic reticulum stress-mediated hepatocyte apoptosis in rats with alcohol-induced liver injury by qinggan huoxue recipe and its disassembled formulas]. elF2alpha, GRP78, HXR, pelF-2alpha, QGHXR, QGR, tHcy
36  2011 [Effects of sarcoplasmic reticulum Ca(2+)-ATPase gene transfer in a minipig model of chronic ischemic heart failure]. CMI, EGFP, GRP78, HF, LAD, SERCA2a
37  2011 [Endoplasmic reticulum stress and related apoptosis in the lungs of a chronic obstructive pulmonary disease rat model]. CHOP, GRP78, LPS, RT-PCR, TUNEL
38  2012 Activation and crosstalk between the endoplasmic reticulum road and JNK pathway in ischemia-reperfusion brain injury. JNK, MCAO/R
39  2012 Apoptosis induced by adenosine involves endoplasmic reticulum stress in EC109 cells. EC, EMSA, TUNEL
40  2012 Autophagy can repair endoplasmic reticulum stress damage of the passive Heymann nephritis model as revealed by proteomics analysis. ---
41  2012 Differential targeting of androgen and glucocorticoid receptors induces ER stress and apoptosis in prostate cancer cells: a novel therapeutic modality. AR, BZ, CpdA, GR, PC, PCa
42  2012 Distinct roles of different forms of vitamin E in DHA-induced apoptosis in triple-negative breast cancer cells. alphaT, DHA, DR5, ROS, siRNAs, TNBC
43  2012 Effect of laminarin on the expression of GRP78 and GRP94 in rat after unilateral ureteral obstruction. BUN, SCr, UUO
44  2012 Endoplasmic reticulum stress and its regulator XBP-1 contributes to dendritic cell maturation and activation induced by high mobility group box-1 protein. DC, HMGB1, MHC, RAGE, UPR
45  2012 Endoplasmic reticulum stress contributes to arsenic trioxide-induced apoptosis in drug-sensitive and -resistant leukemia cells. ---
46  2012 Inhibition of glycogen synthase kinase 3beta ameliorates D-GalN/LPS-induced liver injury by reducing endoplasmic reticulum stress-triggered apoptosis. ALF, CHOP, GSK3beta, LPS
47  2012 Minimally modified low-density lipoprotein induces macrophage endoplasmic reticulum stress via toll-like receptor 4. ATF6, GRP78, mm-LDL, p-IRE1, TLR4, UPR
48  2012 Panax quinquefolium saponins reduce myocardial hypoxia-reoxygenation injury by inhibiting excessive endoplasmic reticulum stress. H-R
49  2012 Preferential killing of triple-negative breast cancer cells in vitro and in vivo when pharmacological aggravators of endoplasmic reticulum stress are combined with autophagy inhibitors. CQ, DMC, ERSA, TNBC
50  2012 Reactive oxygen species-triggered trophoblast apoptosis is initiated by endoplasmic reticulum stress via activation of caspase-12, CHOP, and the JNK pathway in Toxoplasma gondii infection in mice. Gpx6, MDA, NAC, Nox1, ROS
51  2012 Sulfur dioxide inhibits excessively activated endoplasmic reticulum stress in rats with myocardial injury. AAT, ISO
52  2012 The chemical chaperone 4-phenylbutyric acid attenuates pressure-overload cardiac hypertrophy by alleviating endoplasmic reticulum stress. HW/BW, PBA
53  2012 The nephroprotective effect of tauroursodeoxycholic acid on ischaemia/reperfusion-induced acute kidney injury by inhibiting endoplasmic reticulum stress. AKI, CHOP, I/R, TUDCA
54  2012 Trichostatin A ameliorates myocardial ischemia/reperfusion injury through inhibition of endoplasmic reticulum stress-induced apoptosis. CHOP, I/R, TSA
55  2012 [Expressions of endoplasmic reticulum stress associated proteins in livers of severely burned rats]. CHOP, GRP78, TUNEL
56  2012 [Research of eye diseases associated with PERK mediated endoplasmic reticulum stress]. ---
57  2012 [Role of endoplasmic reticulum stress during myocardial apoptosis in rats with severe burn injury]. CHOP, GRP78, TEM
58  2012 [Role of endoplasmic reticulum stress in alcoholic liver disease-related hepatocyte apoptosis]. ALD, CBS, GRP, tHcy
59  2013 Activating transcription factor 4 is involved in endoplasmic reticulum stress-mediated apoptosis contributing to vascular calcification. ATF4, VC, VSMC
60  2013 Adiponectin protects the genioglossus of rats against chronic intermittent hypoxia-induced injury via inhibition of endoplasmic reticulum stress. Ad, ATF6, BAX, CHOP, CIH, ELISA, GRP78, p-eIF2a, p-IRE1a
61  2013 Effect of caspase-9 inhibition on endoplasmic reticulum stress induced cortical neuronal injury in rats. FITC, GRP, NSE
62  2013 Effective Components of Panax quinquefolius and Corydalis tuber Protect Myocardium through Attenuating Oxidative Stress and Endoplasmic Reticulum Stress. 8-iso-PGF2 alpha, AMI, CHOP, ELISA, EPC, GRP78, MDA, SOD
63  2013 Endoplasmic reticulum stress leads to lipid accumulation through upregulation of SREBP-1c in normal hepatic and hepatoma cells. AEBSF, FAS
64  2013 Free fatty acid induces endoplasmic reticulum stress and apoptosis of beta-cells by Ca2+/calpain-2 pathways. FFAs, T2DM
65  2013 Ghrelin protects heart against ERS-induced injury and apoptosis by activating AMP-activated protein kinase. AMPK, CaMKK, CHOP, DTT, GHS-R, I/R, ISO, TM
66  2013 Hypoxic preconditioning protects microvascular endothelial cells against hypoxia/reoxygenation injury by attenuating endoplasmic reticulum stress. CHOP, ECs, GRP78, HPC, LDH, MVECs, p38 MAPK
67  2013 Icariin protects rat cardiac H9c2 cells from apoptosis by inhibiting endoplasmic reticulum stress. ROS
68  2013 Improvements in the primary culture of neonate rat myocardial cells by study of the mechanism of endoplasmic reticulum stress. NRMCs, TM
69  2013 Involvement of endoplasmic reticulum stress in apoptosis of testicular cells induced by low-dose radiation. ATF6, IRE1, LDR, PERK, qRT-PCR
70  2013 Lacidipine inhibits endoplasmic reticulum stress and myocardial remodeling induced by pressure overload in rat heart. CRT, EF, IVST, LVEDP, LVESP, LVPWT, LVWI, TAC
71  2013 Liraglutide Improves the Survival of INS-1 Cells by Promoting Macroautophagy. FFA, T2D, TEM
72  2013 Overexpression of conserved dopamine neurotrophic factor (CDNF) in astrocytes alleviates endoplasmic reticulum stress-induced cell damage and inflammatory cytokine secretion. CDNF, CNS
73  2013 Panax quinquefolium saponin attenuates ventricular remodeling after acute myocardial infarction by inhibiting chop-mediated apoptosis. AMI, CHOP, LV, PQS
74  2013 Restraint stress aggravates rat kidney injury caused by a crush injury through endoplasmic reticulum stress. Sal
75  2013 Role of endoplasmic reticulum stress induction by the plant toxin, persin, in overcoming resistance to the apoptotic effects of tamoxifen in human breast cancer cells. ---
76  2013 Serum- and glucocorticoid-induced protein kinase 1 (SGK1) is regulated by store-operated Ca2+ entry and mediates cytoprotection against necrotic cell death. SGK1, TG
77  2013 Sodium tauroursodeoxycholate prevents paraquat-induced cell death by suppressing endoplasmic reticulum stress responses in human lung epithelial A549 cells. TUDCA
78  2013 Surfactin-induced apoptosis through ROS-ERS-Ca2+-ERK pathways in HepG2 cells. ERK, ROS, Ry
79  2013 The chemical chaperon 4-phenylbutyric acid ameliorates hepatic steatosis through inhibition of de novo lipogenesis in high-fructose-fed rats. HFru, PBA
80  2013 The effect of Chinese Jinzhida recipe on the hippocampus in a rat model of diabetes-associated cognitive decline. DACD, JNK, JZD, T2DM
81  2013 The hyperglycemia stimulated myocardial endoplasmic reticulum (ER) stress contributes to diabetic cardiomyopathy in the transgenic non-obese type 2 diabetic rats: a differential role of unfolded protein response (UPR) signaling proteins. DM, ER, SDT, UPR
82  2013 Unfolded protein response and activated degradative pathways regulation in GNE myopathy. AbetaPP, ERAD, GRP78, GRP94, p-tau, UPR, UPS, VCP
83  2013 [Effects of endoplasmic reticulum stress related proteins and their mediated apoptosis in the formation of deep tissue injury of pressure ulcer in rats]. BiP, CHOP, PDI
84  2013 [Effects of erythropoietin on cardiomyocyte apoptosis and endoplasmic reticulum stress-related proteins in neonatal rats with asphyxia]. CHOP, CK, EPO, GRP78, LDH
85  2013 [Effects of lipoxinA4 on endoplasmic reticulum stress during myocardial ischemia reperfusion injury in rats]. cTnI, LX, MDA, MIRI, MPO, NS, SOD
86  2013 [Inhibitory effect of quercetin preconditioning on tunicamycin-induced apoptosis in macrophages and its mechanism]. ATF6, CHOP, Que, TM
87  2013 [Study on antagonistic effect of liangxue huayu recipe on endoplasmic reticulum stress-induced L02 hepatocyte apoptosis and its mechanism]. LHR, TNF-alpha
88  2013 [The relationship of endoplasmic reticulum stress with paraquat induced lung fibrosis in rats]. alpha-SMA, GRP78, HE, MDA, SD
89  2014 4-phenylbutyric acid attenuates endoplasmic reticulum stress-mediated pancreatic beta-cell apoptosis in rats with streptozotocin-induced diabetes. 4-PBA, 4-PBA group, DM, STZ
90  2014 Amelioration of insulin resistance by Rk1 + Rg5 complex under endoplasmic reticulum stress conditions. ---
91  2014 Atorvastatin ameliorates myocardial ischemia/reperfusion injury through attenuation of endoplasmic reticulum stress-induced apoptosis. CHOP, I/R, LAD, p-JNK, TTC, TUNEL
92  2014 Beta-blocker timolol alleviates hyperglycemia-induced cardiac damage via inhibition of endoplasmic reticulum stress. NAC
93  2014 Deletion of p18(INK4c) aggravates cisplatin-induced acute kidney injury. AKI, CDKIs
94  2014 Effect of lithium chloride on endoplasmic reticulum stress-related PERK/ROCK signaling in a rat model of glaucoma. GSK-3beta, IOP, LiCl, RGCs
95  2014 Effects of an astragalus polysaccharide and rhein combination on apoptosis in rats with chronic renal failure. APS, CRF
96  2014 Endoplasmic reticulum stress in diethylnitrosamine-induced rat liver cancer. DEN
97  2014 Endoplasmic reticulum stress is involved in restraint stress-induced hippocampal apoptosis and cognitive impairments in rats. CHOP, RS, sXBP-1, UPR
98  2014 Endoplasmic reticulum stress mediates the anti-inflammatory effect of ethyl pyruvate in endothelial cells. EC, EP, HUVECs, TNF-alpha
99  2014 Endoplasmic reticulum stress plays critical role in brain damage after chronic intermittent hypoxia in growing rats. CIH, OSAHS
100  2014 Endoplasmic reticulum stress-mediated apoptosis is activated in intestines of mice with Trichinella spiralis infection. ---
101  2014 Endoplasmic reticulum stress-unfolding protein response-apoptosis cascade causes chondrodysplasia in a col2a1 p.Gly1170Ser mutated mouse model. ---
102  2014 Guanxinkang Decoction Exerts Its Antiatherosclerotic Effect Partly through Inhibiting the Endoplasmic Reticulum Stress. GXK, Hcy, HUVEC, MMP
103  2014 Hallmarks of triple negative breast cancer emerging at last? TNBC
104  2014 Hypothalamic endoplasmic reticulum stress and insulin resistance in offspring of mice dams fed high-fat diet during pregnancy and lactation. SC-O
105  2014 Metformin protects the myocardium against isoproterenol-induced injury in rats through alleviating endoplasmic reticulum stress. AMPK, ISO
106  2014 N-acetylcysteine prevents endoplasmic reticulum stress elicited in macrophages by serum albumin drawn from chronic kidney disease rats and selectively affects lipid transporters, ABCA-1 and ABCG-1. AGE, CKD, NAC, TC, TG
107  2014 Neuroprotection by (-)-epigallocatechin-3-gallate in a rat model of stroke is mediated through inhibition of endoplasmic reticulum stress. CHOP, EGCG, ERK, GRP78, MEK
108  2014 Nuclear factor-kappaB as a link between endoplasmic reticulum stress and inflammation during cardiomyocyte hypoxia/reoxygenation. TM
109  2014 Panax quinquefolium saponin attenuates cardiomyocyte apoptosis and opening of the mitochondrial permeability transition pore in a rat model of ischemia/reperfusion. AI, CK-MB, I/R, LAD, mPTP, PQS
110  2014 Polyamine depletion attenuates isoproterenol-induced hypertrophy and endoplasmic reticulum stress in cardiomyocytes. ANP, CHOP, DFMO, GRP78, ISO, LDH, MDA, ODC, SSAT
111  2014 Polyphenon E(R), a standardized green tea extract, induces endoplasmic reticulum stress, leading to death of immortalized PNT1a cells by anoikis and tumorigenic PC3 by necroptosis. PCa, UPR
112  2014 Postprandial inflammation is not associated with endoplasmic reticulum stress in peripheral blood mononuclear cells from healthy lean men. HFM, PBMC, UDCA
113  2014 Role of endoplasmic reticulum stress in apoptosis of differentiated mouse podocytes induced by high glucose. C/EBP, DN, ERAD, GRP78
114  2014 The impact of intermittent and repetitive cold stress exposure on endoplasmic reticulum stress and instability of atherosclerotic plaques. ATF6, IRE1, oxLDL, p-ERK
115  2014 TNF/TNFR₁ pathway and endoplasmic reticulum stress are involved in ofloxacin-induced apoptosis of juvenile canine chondrocytes. ---
116  2014 Toxoplasma gondii induce apoptosis of neural stem cells via endoplasmic reticulum stress pathway. CHOP, JNK, NSCs
117  2014 [Changes of endoplasmic reticulum stress- and apoptosis-related factors in rat cerebral cortex following controlled hypotension]. CHOP, GRP78
118  2014 [Effects of adiponectin on endoplasmic reticulum stress-mediated apoptosis and cell cytoskeleton and its mechanism of podocytes cultured in high glucose]. APN, PCR
119  2014 [Endoplasmic reticulum stress and vascular endothelial cell apoptosis]. UPR
120  2014 [Endoplasmic reticulum stress mediates lipopolysaccharide-induced apoptosis in rat hepatocyte]. 4-PBA, LPS, TG
121  2014 [Endoplasmic reticulum stress mediates oxidized low density lipoprotein-induced scavenger receptor A1 upregulation in macrophages]. GRP78, oxLDL, PBA, SR-A1, TC, TG, TM
122  2014 [Expression of calcineurin in podocytes in response to endoplasmic reticulum stress in diabetic nephropathy]. CaN, DN, UDCA
123  2014 [Ophiopogonin D protects cardiomyocytes against doxorubicin-induced injury through suppressing endoplasmic reticulum stress]. NAC, OP-D, ROS
124  2014 [Preliminary investigation into the mechanism of cardiomyocyte hypertrophy induced by visfatin]. ANP, ATF6, BNP, CHOP, GRP78
125  2014 [Role of endoplasmic reticulum stress in D-GalN/LPS-induced acute liver failure]. 4-PBA, ALF, AST, i.p
126  2014 [Role of endoplasmic reticulum stress pathway in podophyllotoxin nanostructured lipid carriers-induced apoptosis of VK2/E6E7 cells]. LSCM, POD-NLC
127  2014 [Total flavonoids from Astragalus complanatus attenuates lung injury following paraquat poisoning in rats through inhibiting excessive endoplasmic reticulum stress and c-Jun N-terminal kinase pathway]. DMSO, FAC, GRP78, IQA, JNK, p-JNK, PQ, RT-PCR, SD, TLW
128  2015 C/EBP homologous protein-mediated endoplasmic reticulum stress-related renal apoptosis is involved in rats with brain death. BD, CHOP, Sal
129  2015 Carbon monoxide offers neuroprotection from hippocampal cell damage induced by recurrent febrile seizures through the PERK-activated ER stress pathway. CHOP, CO, FSs, GRP78, p-PERK
130  2015 Carbonic Anhydrase Protects Fatty Liver Grafts against Ischemic Reperfusion Damage. AMPK, CAs, IRI, MAPKs
131  2015 Chronic intermittent hypobaric hypoxia ameliorates endoplasmic reticulum stress mediated liver damage induced by fructose in rats. CIHH, CIHH-F, CON, GRP78, NAFLD, TC, TG
132  2015 Cortistatin protects myocardium from endoplasmic reticulum stress induced apoptosis during sepsis. CLP, CM, CST, DTT, LPS
133  2015 Curcumin ameliorates streptozotocin-induced liver damage through modulation of endoplasmic reticulum stress-mediated apoptosis in diabetic rats. STZ, UPR
134  2015 Different Eukaryotic Initiation Factor 2Bepsilon Mutations Lead to Various Degrees of Intolerance to the Stress of Endoplasmic Reticulum in Oligodendrocytes. ATF4, eIF2B, GEF, UPR, VWM
135  2015 Down-regulation of C/EBP homologous protein (CHOP) expression in gastric cardia adenocarcinoma: Their relationship with clinicopathological parameters and prognostic significance. CHOP, GCA, qRT-PCR
136  2015 Effect of low-dose cyclophosphamide on endoplasmic reticulum stress and inflammatory reaction of acute renal ischemia reperfusion injury. CHOP, CP, ICAM-1, IRI
137  2015 Effects of hyperbaric oxygen on glucose-regulated protein 78 and c-Jun N-terminal kinase expression after spinal cord injury in rats. GRP, HBO, JNK, SCI
138  2015 Effects of the Combination of the Main Active Components of Astragalus and Panax notoginseng on Inflammation and Apoptosis of Nerve Cell after Cerebral Ischemia-Reperfusion. CCA, GRP78, I/R, NF-kappaB, p-STAT1
139  2015 Endoplasmic reticulum stress impairs insulin receptor signaling in the brains of obese rats. HFD, IRE-1alpha, IRS-1, JNK, PERK
140  2015 Endoplasmic reticulum stress participates in the progress of senescence of bone marrow-derived mesenchymal stem cells in patients with systemic lupus erythematosus. 4-PBA, BM-MSCs, GRP78, SLE
141  2015 Endoplasmic reticulum stress pathway mediates isoflurane-induced neuroapoptosis and cognitive impairments in aged rats. ATF, CHOP, eIF, POCD
142  2015 Endoplasmic reticulum stress-mediated apoptotic pathway is involved in corpus luteum regression in rats. ATF6alpha, CHOP, CL, eIF2alpha, GRP78, IRE1alpha, PCR, XBP1
143  2015 Enhanced antitumor effect of shikonin by inhibiting Endoplasmic Reticulum Stress via JNK/c-Jun pathway in human glioblastoma stem cells. 4-PBA, GSCs, MMP
144  2015 H2 and H3 relaxin inhibit high glucose-induced apoptosis in neonatal rat ventricular myocytes. H2 relaxin, HG, NRVMs
145  2015 Hepatic Overexpression of GRP94 in a Rabbit Model of Parenteral Nutrition-Associated Liver Disease. GRP94, PNALD, TPN
146  2015 Histidine-rich calcium binding protein promotes growth of hepatocellular carcinoma in vitro and in vivo. 4-PBA, CDK2, HCC, HRC, TG
147  2015 Hypertension-mediated enhancement of JNK activation in association with endoplasmic reticulum stress in rat model hippocampus with cerebral ischemia-reperfusion. JNKs
148  2015 IL-15 expression increased in response to treadmill running and inhibited endoplasmic reticulum stress in skeletal muscle in rats. DTT, HFD, IL-15, IL-15Ralpha, IR, TM
149  2015 Induction of Apoptosis Coupled to Endoplasmic Reticulum Stress through Regulation of CHOP and JNK in Bone Marrow Mesenchymal Stem Cells from Patients with Systemic Lupus Erythematosus. 4-PBA, Bax, Bcl-2, BM-MSCs, eIF-2alpha, IRE1, PERK, SLE
150  2015 Intermedin protects against renal ischemia-reperfusion injury by inhibiting endoplasmic reticulum stress. CHOP, GRP78, IMD, IRI, LDH
151  2015 Intermedin1-53 protects against cardiac hypertrophy by inhibiting endoplasmic reticulum stress via activating AMP-activated protein kinase. AAC, ANP, BNP, CHOP, GRP78, IMD, pAMPK
152  2015 Involvement of endoplasmic reticulum stress in angiotensin II-induced NLRP3 inflammasome activation in human renal proximal tubular cells in vitro. Ang II
153  2015 IRE1alpha-XBP1 Pathway Is Activated Upon Induction of Single-Prolonged Stress in Rat Neurons of the Medial Prefrontal Cortex. mPFC, mRNA, PTSD, qRT-PCR, SPS, TUNEL
154  2015 Isolation and antitumor efficacy evaluation of a polysaccharide from Nostoc commune Vauch. ---
155  2015 Melatonin inhibits tunicamycin-induced endoplasmic reticulum stress and insulin resistance in skeletal muscle cells. BiP, GRP78, IRE1, IRS-1, JNK, PERK, T2D, XBP1
156  2015 miR-15b-5p induces endoplasmic reticulum stress and apoptosis in human hepatocellular carcinoma, both in vitro and in vivo, by suppressing Rab1A. HCC, RT-PCR
157  2015 Molecular hydrogen stabilizes atherosclerotic plaque in low-density lipoprotein receptor-knockout mice. oxLDL, ROS
158  2015 Molecular mechanism of ER stress-induced gene expression of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) in macrophages. TG, TM, TRAIL
159  2015 N-acetylcysteine Ameliorates the Erectile Dysfunction Caused by Chronic Intermittent Hypoxia in Rats: Partly Involvement of Endoplasmic Reticulum Stress. CIH, ED, NAC, NO, NOS
160  2015 PDIA3 Knockdown Exacerbates Free Fatty Acid-Induced Hepatocyte Steatosis and Apoptosis. CHOP, FAS, GRP78, NAFLD, p-PERK, PDIA3
161  2015 PPARalpha Agonist WY-14643 Induces SIRT1 Activity in Rat Fatty Liver Ischemia-Reperfusion Injury. IRI, PPARalpha, SIRT1
162  2015 Preconditioning With Tauroursodeoxycholic Acid Protects Against Contrast-Induced HK-2 Cell Apoptosis by Inhibiting Endoplasmic Reticulum Stress. ATF4, CM, GRP78, mRNA, TUDCA
163  2015 Protection of cultured human hepatocytes from hydrogen peroxide‑induced apoptosis by relaxin‑3. ---
164  2015 Quercetin induces endoplasmic reticulum stress to enhance cDDP cytotoxicity in ovarian cancer: involvement of STAT3 signaling. QU
165  2015 Salubrinal protects cardiomyocytes against apoptosis in a rat myocardial infarction model via suppressing the dephosphorylation of eukaryotic translation initiation factor 2alpha. MI
166  2015 Sodium Citrate Inhibits Endoplasmic Reticulum Stress in Rats with Adenine-Induced Chronic Renal Failure. CRF
167  2015 Stress of endoplasmic reticulum modulates differentiation and lipogenesis of human adipocytes. TG, TM, UPR
168  2015 The Chondroprotective Role of TMF in PGE2-Induced Apoptosis Associating with Endoplasmic Reticulum Stress. TMF
169  2015 The Protective Effect of Lacidipine on Myocardial Remodeling Is Mediated by the Suppression in Expression of GPR78 and CHOP in Rats. LAC, LVMI, SHR
170  2015 The role of endoplasmic reticulum stress and insulin resistance in the occurrence of goose fatty liver. IR
171  2015 Toxoplasma gondii prevalent in China induce weaker apoptosis of neural stem cells C17.2 via endoplasmic reticulum stress (ERS) signaling pathways. ---
172  2015 Trinitrotoluene Induces Endoplasmic Reticulum Stress and Apoptosis in HePG2 Cells. CHOP, GRP, JNK, TNT
173  2015 [A study of lymphocyte apoptosis and endoplasmic reticulum stress in the development of sepsis and their association with outcome in septic patients]. GRP78, ICU, RT-PCR
174  2015 [Effect of endoplasmic reticulum stress on the expression and osteogenic differentiation of periodontal ligament stem cells]. ALP, ATF4, CHOP, GRP78, LPS, OCN, PDLSC, PERK, RT, TG
175  2015 [Effects of HO-1 on Lipopolysaccharide-induced Endoplasmic Reticulum Stress of Rat Hepatocytes]. HO-1, LPS
176  2015 [Endoplasmic reticulum stress collaborates with lipopolysaccharide to promote the inflammatory response in macrophages]. ---
177  2015 [Preliminary study on the pathogenic mechanism of myoglobin-induced endoplasmic reticulum stress and apoptosis in crush syndrome]. AKI, SCr
178  2015 [Role of KA1 receptor in excitotoxic neurodegeneration in mouse hippocampus triggered by kainic acid- or tunicamycin-induced endoplasmic reticulum stress]. KA, TM
179  2015 [The role of cell apoptosis mediated by endoplasmic reticulum stress (ERS) of deep tissue injury of pressure ulcer of rats]. 4-PBA, DTI, GRP78
180  2016 Activation of endoplasmic reticulum stress promotes autophagy and apoptosis and reverses chemoresistance of human small cell lung cancer cells by inhibiting the PI3K/AKT/mTOR signaling pathway. SCLC
181  2016 Alpha-ketoglutarate enhances milk protein synthesis by porcine mammary epithelial cells. AKG, DMEM-F12, mTOR, PMECs
182  2016 Associations between autophagy, the ubiquitin-proteasome system and endoplasmic reticulum stress in hypoxia-deoxygenation or ischemia-reperfusion. I/R, UPS
183  2016 Attenuation of Endoplasmic Reticulum Stress-Mediated Liver Damage by Mulberry Leaf Diet in Streptozotocin-Induced Diabetic Rats. CHOP, GRP78, MLD, MLs, PERK, SD, SREBP 1c, STZ, TRAF2, XBP1
184  2016 Berberine Improved Aldo-Induced Podocyte Injury via Inhibiting Oxidative Stress and Endoplasmic Reticulum Stress Pathways both In Vivo and In Vitro. ALDO, OS
185  2016 Bis(maltolato)oxovanadium(IV) (BMOV) Attenuates Apoptosis in High Glucose-Treated Cardiac Cells and Diabetic Rat Hearts by Regulating the Unfolded Protein Responses (UPRs). BMOV, DCM, ER, ROS, STZ, UPR, UPRs
186  2016 C1q/TNF-Related Protein 9 Protects Diabetic Rat Heart against Ischemia Reperfusion Injury: Role of Endoplasmic Reticulum Stress. CTRP9, DsbA-L, ER, HFD, IR, SIR, TG
187  2016 Ca2+-Dependent Endoplasmic Reticulum Stress Regulates Mechanical Stress-Mediated Cartilage Thinning. ER
188  2016 Cardioprotective effects of Notoginsenoside R1 against ischemia/reperfusion injuries by regulating oxidative stress- and endoplasmic reticulum stress- related signaling pathways. I/R, LVSP, NGR1
189  2016 Caspase-12 is involved in stretch-induced apoptosis mediated endoplasmic reticulum stress. RT-PCR
190  2016 Characterization and Inducing Melanoma Cell Apoptosis Activity of Mannosylerythritol Lipids-A Produced from Pseudozyma aphidis. CMC, MELs
191  2016 Chronic intermittent hypobaric hypoxia attenuates radiation induced heart damage in rats. CIHH, LVDP, LVEDP, RIHD
192  2016 Effects of endoplasmic reticulum stress on the expression of inflammatory cytokines in patients with ulcerative colitis. IFN, IL, PHA, TG, UC, XBP1s
193  2016 Effects of probucol on cultured human umbilical vein endothelial cells injured by hypoxia/reoxygenation. HUVECs, LDH, XBP
194  2016 Emodin ameliorates hepatic steatosis through endoplasmic reticulum-stress sterol regulatory element-binding protein 1c pathway in liquid fructose-feeding rats. AST, GRP78, SREBP-1c, TG, UPR
195  2016 Endoplasmic reticulum protein 29 is involved in endoplasmic reticulum stress in islet beta cells. BiP, ERp29, GRP78
196  2016 Endoplasmic reticulum stress induces secretion of high-mobility group proteins and is associated with tumor-infiltrating lymphocytes in triple-negative breast cancer. TILs, TNBC
197  2016 Endoplasmic Reticulum Stress Induces the Early Appearance of Pro-apoptotic and Anti-apoptotic Proteins in Neurons of Five Familial Alzheimer's Disease Mice. AD, CHOP, GRP, SYVN1, UPR, WT
198  2016 Endoplasmic reticulum stress intolerance in EIF2B3 mutant oligodendrocytes is modulated by depressed autophagy. Atg, eIF2B, UPR, VWM
199  2016 Endoplasmic reticulum stress is activated in acute pancreatitis. ER
200  2016 Endoplasmic Reticulum Stress Is Implicated in Intestinal Failure-Associated Liver Disease. IFALD
201  2016 Endoplasmic Reticulum Stress is Involved in DFMO Attenuating Isoproterenol-Induced Cardiac Hypertrophy in Rats. ANP, CHOP, DFMO, GRP78, ISO, ODC, SSAT
202  2016 Endoplasmic reticulum stress mediates JNK-dependent IRS-1 serine phosphorylation and results in Tau hyperphosphorylation in amyloid beta oligomer-treated PC12 cells and primary neurons. Abeta1-42, AD, IRS-1
203  2016 Endoplasmic Reticulum Stress Predicts Clinical Response to Cyclosporine Treatment in Primary Membranous Nephropathy. GRP78, PMN
204  2016 Endoplasmic reticulum stress: a novel mechanism and therapeutic target for cardiovascular diseases. UPR
205  2016 Equol Attenuates Atherosclerosis in Apolipoprotein E-Deficient Mice by Inhibiting Endoplasmic Reticulum Stress via Activation of Nrf2 in Endothelial Cells. HFD, HUVECs
206  2016 Expression and Distribution of Mesencephalic Astrocyte-Derived Neurotrophic Factor in the Retina and Optic Nerve. ARMET, GCL, GFAP, INL, MANF, ON, RGCs
207  2016 Expression levels of urotensin II are associated with endoplasmic reticulum stress in patients with severe preeclampsia. CHOP, sPE, UII
208  2016 Fluoxetine synergizes with temozolomide to induce the CHOP-dependent endoplasmic reticulum stress-related apoptosis pathway in glioma cells. CI, FLT, TMZ
209  2016 Glycated LDL increase VCAM-1 expression and secretion in endothelial cells and promote monocyte adhesion through mechanisms involving endoplasmic reticulum stress. gLDL, HEC, NAC, PBA, ROS, Sal, VCAM-1
210  2016 Guggulsterone-induced apoptosis in cholangiocarcinoma cells through ROS/JNK signaling pathway. CCA, ROS
211  2016 Hepatoprotective Effect of Quercetin on Endoplasmic Reticulum Stress and Inflammation after Intense Exercise in Mice through Phosphoinositide 3-Kinase and Nuclear Factor-Kappa B. ATF6, JNK, PI3K
212  2016 High-density lipoprotein inhibits ox-LDL-induced adipokine secretion by upregulating SR-BI expression and suppressing ER Stress pathway. CHOP, FC, HDL, oxLDL, PBA, SR-BI
213  2016 Honokiol induces autophagy of neuroblastoma cells through activating the PI3K/Akt/mTOR and endoplasmic reticular stress/ERK1/2 signaling pathways and suppressing cell migration. 3-MA, ERK, GpR, LC3, mTOR, PI3K, ROS
214  2016 Hydrogen Sulfide Improves Vascular Calcification in Rats by Inhibiting Endoplasmic Reticulum Stress. VC, VSMC
215  2016 Hyperglycemia attenuates remifentanil postconditioning-induced cardioprotection againsthypoxia/reoxygenation injury inH9c2cardiomyoblasts. ---
216  2016 Icariin displays anticancer activity against human esophageal cancer cells via regulating endoplasmic reticulum stress-mediated apoptotic signaling. ESCC, ICA, NADPH, ROS
217  2016 Impact of activating transcription factor 4 signaling on lipogenesis in HepG2 cells. ACC, ATF4, ChREBP, FAS, NAFLD, TG
218  2016 Inhibition of TRB3 Protects Photoreceptors against Endoplasmic Reticulum Stress-Induced Apoptosis after Experimental Retinal Detachment. LV-TRB3-sh, ONL, RD, TRB3, TUNEL
219  2016 Intermedin Restores Hyperhomocysteinemia-induced Macrophage Polarization and Improves Insulin Resistance in Mice. HHcy, IMD
220  2016 Intermedin1-53 Protects Against Myocardial Fibrosis by Inhibiting Endoplasmic Reticulum Stress and Inflammation Induced by Homocysteine in Apolipoprotein E-Deficient Mice. ATF6, CFs, GRP78, Hcy, IL-6, IMD1-53
221  2016 Involvement of Endoplasmic Reticulum Stress in Uremic Cardiomyopathy: Protective Effects of Tauroursodeoxycholic Acid. TUDCA, UCM
222  2016 Low dose tunicamycin enhances atherosclerotic plaque stability by inducing autophagy. TM
223  2016 MicroRNA-93 inhibits ischemia-reperfusion induced cardiomyocyte apoptosis by targeting PTEN. I/R, PTEN
224  2016 miRNA-1283 Regulates the PERK/ATF4 Pathway in Vascular Injury by Targeting ATF4. ATF4, ATF6, eIF2alpha, HUVECs, IRE1, miRNA, PERK
225  2016 Molecular Mechanisms of Stress-Induced Myocardial Injury in a Rat Model Simulating Posttraumatic Stress Disorder. PTSD, SPS
226  2016 Novel Role of ER Stress and Autophagy in Microcystin-LR Induced Apoptosis in Chinese Hamster Ovary Cells. CHO, MC-LR
227  2016 Overexpressed cyclophilin B suppresses aldosterone-induced proximal tubular cell injury both in vitro and in vivo. CHOP, CyP, GRP78, HK-2, PPIase, RAAS
228  2016 Penehyclidine Hydrochloride Pretreatment Ameliorates Rhabdomyolysis-Induced AKI by Activating the Nrf2/HO-1 Pathway and Alleviating [corrected] Endoplasmic Reticulum Stress in Rats. The. AKI, GRP78, HO-1, Nrf2, PHC, RM
229  2016 PERK-eIF2alpha-ATF4 pathway mediated by endoplasmic reticulum stress response is involved in osteodifferentiation of human periodontal ligament cells under cyclic mechanical force. ATF4, ER, PDLCs, PERK
230  2016 Pterostilbene exerts an anti-inflammatory effect via regulating endoplasmic reticulum stress in endothelial cells. HUVECs, PT, THA, TNF-alpha
231  2016 Quercetin stimulates mitochondrial apoptosis dependent on activation of endoplasmic reticulum stress in hepatic stellate cells. HSCs
232  2016 Reduced AKT phosphorylation contributes to endoplasmic reticulum stress-mediated hippocampal neuronal apoptosis in rat recurrent febrile seizure. CHOP, FS, GRP78, SD, TRIB3, TUNEL
233  2016 Relevance of Endoplasmic Reticulum Stress Cell Signaling in Liver Cold Ischemia Reperfusion Injury. ER, IRI, UPR
234  2016 Roles of endoplasmic reticulum stress, apoptosis and autophagy in 2,2',4,4'-tetrabromodiphenyl ether-induced rat ovarian injury. ---
235  2016 Spermine inhibits Endoplasmic Reticulum Stress-induced Apoptosis: a New Strategy to Prevent Cardiomyocyte Apoptosis. AMI, LAD, ROS
236  2016 Spontaneous nonalcoholic fatty liver disease and ER stress in Sidt2 deficiency mice. NAFLD, TG
237  2016 Supplementing dietary sugar promotes endoplasmic reticulum stress-independent insulin resistance and fatty liver in goose. IR, NAFLD
238  2016 Tanshinone IIA ameliorates apoptosis of cardiomyocytes induced by endoplasmic reticulum stress. miR-133, TM
239  2016 The endoplasmic reticulum stress response: A link with tuberculosis? ER, TB, UPR
240  2016 The protective effect of lycopene on hypoxia/reoxygenation-induced endoplasmic reticulum stress in H9C2 cardiomyocytes. 4-PBA, CHOP, GRP78, I/R, JNK, LDH, p-JNK, TG
241  2016 The Protective effect of the endoplasmic reticulum stress-related factors BiP/GRP78 and CHOP/Gadd153 on noise-induced hearing loss in guinea pigs. ABRs, ANOVA, LSD, NIHL, OHCs
242  2016 The roles of endoplasmic reticulum stress response in female mammalian reproduction. ---
243  2016 The signaling mechanisms of hippocampal endoplasmic reticulum stress affecting neuronal plasticity-related protein levels in high fat diet-induced obese rats and the regulation of aerobic exercise. BDNF, FATP1, GLUT3, HFD, SYN
244  2016 Tripping on TRIB3 at the junction of health, metabolic dysfunction and cancer. UPR
245  2016 TTF1-NPs Induce ERS-Mediated Apoptosis and Inhibit Human Hepatoma Cell Growth In Vitro and In Vivo. SS, TTF1-NPs
246  2016 TTF1-NPs Induce ERS-Mediated Apoptosis and Inhibit Human Hepatoma Cell Growth In Vitro and In Vivo. SS, TTF1-NPs
247  2016 Update on Mechanisms of Renal Tubule Injury Caused by Advanced Glycation End Products. ABCA1, AGEs, DN, HMG-CoAR, LDLR, LXR, SREBP-2
248  2016 Valproate attenuates diabetic nephropathy through inhibition of endoplasmic reticulum stress‑induced apoptosis. CHOP, DN, VPA
249  2016 [Advanced glycated albumin induces macrophage apoptosis via activating caspase-12 pathway]. AGE-alb, LDH
250  2016 [Association between endoplasmic reticulum stress pathway mediated by inositol-requiring kinase 1 and AECII apoptosis in preterm rats induced by hyperoxia]. AECIIs, CHOP, GRP78, IRE1, XBP1
251  2016 [Autophagy inhibitor 3-methyladenine enhances the sensitivity of nasopharyngeal carcinoma cells to chemotherapy and radiotherapy]. DAPI, GRP78, IR, LC3, TM
252  2016 [Effect of dexmedetomidine on expression of endoplasmic reticulum stress-related Caspase-12 in lung ischemia/reperfusion injury mice]. AI, Caspase-12, DEX, Dex group, I/R, NS group, TLW
253  2016 [Effect of Electroacupunctrue on ERp57 in NAFLD Rats]. EA2, NAFLD
254  2016 [Effect of hydrogen sulfide on oxidative stress and endoplasmic reticulum stress in diabetic cardiomyopathy]. CHOP, DCM, GRP78, GSH-Px, MDA, SOD
255  2016 [Effect of Tongxinluo on Apoptosis of Rat Cardiac Microvascular Endothelial Cells]. caspase-12, CHOP, GRP78, Hcy, P-Akt, p-PI3K, rCMECs, RT-PCR, T-Akt, TXL
256  2016 [Effects of chronic intermittent hypoxia on hepatic function and protective mechanism of adiponectin in rats]. Ad, AST, CIH, NC
257  2016 [Effects of electroacupuncture combined with dietary control on liver endoplasmic reticulum stress in rats with non-alcoholic fatty liver disease]. EA, GRP78, HFD, LFD, NAFLD, TEM
258  2016 [Protection of Fufang Zhenzhu Tiaozhi Formula on NAFLD in Mice by Regulating ERS]. FZT, NAFLD, TC, TG
259  2016 [Salubrinal protects human lens epithelial cells against endoplasmic reticulum stress-associated apoptosis]. ANOVA, Caspase-12, CHOP, FCM, GRP78, HLE-B3, p-elF2alpha
260  2016 [Study on Potential Role of Calreticulin in Pressure Overload Induced Cardiac Hypertrophy]. ISO, NCMs, NE, siRNA, TAC
261  2016 [Study on the Mechanism of Yiqi Chutan Recipe in the Treatment of Lung Cancer with Splenasthenic Syndrome]. YCR
262  2016 [The progress of study about endoplasmic reticulum stress in glaucoma]. UPR
263  2017 An immortalized steroidogenic goat granulosa cell line as a model system to study the effect of the endoplasmic reticulum (ER)-stress response on steroidogenesis. ER, hTERT, TG
264  2017 beta-elemene regulates endoplasmic reticulum stress to induce the apoptosis of NSCLC cells through PERK/IRE1alpha/ATF6 pathway. IHC, NSCLC, QPCR, ROS, WB
265  2017 Cadmium-induced endoplasmic reticulum stress in chicken neutrophils is alleviated by selenium. ATF6, CaM, Cd, COX-2, GRP78, IFN-gamma, IL-10, IL-17, IL-1beta, IL-4, iNOS, NF-kappaB, NO, PGE2, Se
266  2017 Caffeic acid attenuates the inflammatory stress induced by glycated LDL in human endothelial cells by mechanisms involving inhibition of AGE-receptor, oxidative, and endoplasmic reticulum stress. CAF, gLDL, HEC, RAGE
267  2017 Calcium homeostasis and endoplasmic reticulum stress are involved in Salvianolic acid B-offered protection against cardiac toxicity of arsenic trioxide. ATO, Sal B
268  2017 Chronic Intermittent Hypobaric Hypoxia Improves Cardiac Function through Inhibition of Endoplasmic Reticulum Stress. CIHH, LDH, PKC
269  2017 Critical role of X-box binding protein 1 in NADPH oxidase 4-triggered cardiac hypertrophy is mediated by receptor interacting protein kinase 1. Ang II, ISO, NCMs, NOX4, RIPK1, ROS, siRNA, TAC
270  2017 Cytoprotective effects of myristicin against hypoxia‑induced apoptosis and endoplasmic reticulum stress in rat dorsal root ganglion neurons. DRG
271  2017 Diazoxide prevents H2O2-induced chondrocyte apoptosis and cartilage degeneration in a rat model of osteoarthritis by reducing endoplasmic reticulum stress. CCK-8, CHOP, OA
272  2017 Discovery of (4-bromophenyl)(3-hydroxy-4-methoxyphenyl)methanone through upregulating hTERT induces cell apoptosis and ERS. EOR
273  2017 Downregulation of Smac attenuates H2O2-induced apoptosis via endoplasmic reticulum stress in human lens epithelial cells. HLEC, Smac
274  2017 Dual Delivery of NGF and bFGF Coacervater Ameliorates Diabetic Peripheral Neuropathy via Inhibiting Schwann Cells Apoptosis. bFGF, DPN, GFs, NGF
275  2017 Echinacoside's nigrostriatal dopaminergic protection against 6-OHDA-Induced endoplasmic reticulum stress through reducing the accumulation of Seipin. ECH, PD
276  2017 Effects of the Activin A-Follistatin System on Myocardial Cell Apoptosis through the Endoplasmic Reticulum Stress Pathway in Heart Failure. BNP, C/EBP, HF, MI
277  2017 Endoplasmic reticulum stress and apoptosis via PERK-eIF2alpha-CHOP signaling in the methamphetamine-induced chronic pulmonary injury. MA
278  2017 Endoplasmic reticulum stress induces autophagy and apoptosis while inhibiting proliferation and drug resistance in multiple myeloma through the PI3K/Akt/mTOR signaling pathway. ALB, GRP78, IGF-1, LC3, LDH, MM, TM
279  2017 Endoplasmic reticulum stress is involved in apoptosis of detrusor muscle in streptozocin-induced diabetic rats. CHOP, DCP, DSM, ER, GRP78, qRT-PCR, STZ, TEM
280  2017 Endoplasmic reticulum stress participates in the progress of senescence and apoptosis of osteoarthritis chondrocytes. OA, SA-beta-gal
281  2017 Endoplasmic reticulum stress pathway PERK-eIF2alpha confers radioresistance in oropharyngeal carcinoma by activating NF-kappaB. NF-kappaB, PERK
282  2017 Endoplasmic Reticulum Stress Promotes Autophagy and Apoptosis and Reduces Chemotherapy Resistance in Mutant p53 Lung Cancer Cells. CHOP, GRP78, IRE1alpha, LC
283  2017 Endoplasmic reticulum stress promotes autophagy and apoptosis and reverses chemoresistance in human ovarian cancer cells. ---
284  2017 Endoplasmic reticulum stress regulates proliferation, migration and invasion of human ovarian cancer SKOV3 cells through PI3K/AKT/mTOR signaling pathway. OC
285  2017 Endoplasmic reticulum stress responses in placentation - A true balancing act. UPR
286  2017 Escherichia coli aggravates endoplasmic reticulum stress and triggers CHOP-dependent apoptosis in weaned pigs. IPEC-J2, LPS
287  2017 Exogenous H2S restores ischemic post-conditioning-induced cardioprotection through inhibiting endoplasmic reticulum stress in the aged cardiomyocytes. PC
288  2017 Expression and function of HSP110 family in mouse testis after vasectomy. AsAb, ELISA, RT-PCR, TUNEL
289  2017 Gaseous signalling molecule SO2 via Hippo‑MST pathway to improve myocardial fibrosis of diabetic rats. STZ
290  2017 Ghrelin ameliorates atherosclerosis by inhibiting endoplasmic reticulum stress. AS, IMT
291  2017 Glucose regulated protein 78 is potentially an important player in the development of nonalcoholic steatohepatitis. GRP78, NASH
293  2017 Hepatoprotective effect of peony total glucosides and the underlying mechanisms in diabetic rats. TGP
294  2017 Hoxa5 increases mitochondrial apoptosis by inhibiting Akt/mTORC1/S6K1 pathway in mice white adipocytes. Akt, DR, HOXA5, iWAT, mTORC1, PA
295  2017 Hydrogen alleviates hyperoxic acute lung injury related endoplasmic reticulum stress in rats through upregulation of SIRT1. HALI, SIRT1
296  2017 Hydrogen Sulfide Facilitates the Impaired Sensitivity of Carotid Sinus Baroreflex in Rats with Vascular Calcification. ALP, VC, VSMCs
297  2017 Hydrogen Sulfide Inhibits Cigarette Smoke-Induced Endoplasmic Reticulum Stress and Apoptosis in Bronchial Epithelial Cells. 4-PBA, CHOP, COPD, CS, PPG
298  2017 Hydrogen-rich saline attenuates hippocampus endoplasmic reticulum stress after cardiac arrest in rats. caspase-12, CHOP, GRP78, I/R, ROS
299  2017 Increased ERp57 Expression in HBV-Related Hepatocellular Carcinoma: Possible Correlation and Prognosis. CHB, HBV-HCC, IHC
300  2017 Inhibition of Endoplasmic Reticulum Stress Apoptosis by Estrogen Protects Human Umbilical Vein Endothelial Cells Through the PI3 Kinase-Akt Signaling Pathway. CHOP, GRP78, HUVECs, JNK, p38 MAPK, PI3K
301  2017 Isorhynchophylline Attenuates MPP+-Induced Apoptosis Through Endoplasmic Reticulum Stress- and Mitochondria-Dependent Pathways in PC12 Cells: Involvement of Antioxidant Activity. ASK1, DPI, IRE1, IRN, JNK, PD
302  2017 l-Glutamine Attenuates Apoptosis Induced by Endoplasmic Reticulum Stress by Activating the IRE1alpha-XBP1 Axis in IPEC-J2: A Novel Mechanism of l-Glutamine in Promoting Intestinal Health. CHOP, GRP78, IPEC-J2, IRE1alpha, TUNI
303  2017 Long-term thermal manipulation in the late incubation period can inhibit breast muscle development by activating endoplasmic reticulum stress in duck (Anasplatyrhynchos domestica). TM
304  2017 Low Dose of Apelin-36 Attenuates ER Stress-Associated Apoptosis in Rats with Ischemic Stroke. I/R, UPR
305  2017 Magnesium isoglycyrrhizinate promotes the activated hepatic stellate cells apoptosis via endoplasmic reticulum stress and ameliorates fibrogenesis in vitro and in vivo. HSCs, MgIG
306  2017 MAPK pathway regulated the cardiomyocyte apoptosis in mice with post-infarction heart failure. HF, MI
307  2017 Mechanical and hypoxia stress can cause chondrocytes apoptosis through over-activation of endoplasmic reticulum stress. HE, OA, PI
308  2017 Melatonin Relieves Busulfan-Induced Spermatogonial Stem Cell Apoptosis of Mouse Testis by Inhibiting Endoplasmic Reticulum Stress. ---
309  2017 Mitochondria-Targeted Antioxidant Mito-Tempo Protects Against Aldosterone-Induced Renal Injury In Vivo. ALDO, CKD, MtD, mtROS
310  2017 Modulation of AbetaPP and GSK3beta by Endoplasmic Reticulum Stress and Involvement in Alzheimer's Disease. AbetaPP, AD, GSK3beta
311  2017 Molecular Mechanisms of IRE1alpha-ASK1 Pathway Reactions to Unfolded Protein Response in DRN Neurons of Post-Traumatic Stress Disorder Rats. DRN, IHC, PTSD, SPS
312  2017 Necrostatin-1 Mitigates Endoplasmic Reticulum Stress After Spinal Cord Injury. CHOP, Nec-1, SCI, XBP1
313  2017 Nickel sulfate induced apoptosis via activating ROS-dependent mitochondria and endoplasmic reticulum stress pathways in rat Leydig cells. NAC, ROS, TEMPO
314  2017 Overexpressed PLTP in macrophage may promote cholesterol accumulation by prolonged endoplasmic reticulum stress. AS, FC, PL, PLTP
315  2017 PCSK9 regulates apoptosis in human lung adenocarcinoma A549 cells via endoplasmic reticulum stress and mitochondrial signaling pathways. PCSK9, si
316  2017 Protective effect of 2-deoxy-D-glucose on the brain tissue in rat cerebral ischemia-reperfusion models by inhibiting Caspase-apoptotic pathway. 2-DG, GRP78, I/R
317  2017 Protective Effects of Glucagon-Like Peptide-1 Analog on Renal Tubular Injury in Mice on High-Fat Diet. AT1R, GLP-1, HFD
318  2017 Protective effects of isorhamnetin on N2a cell against endoplasmic reticulum stress-induced injury is mediated by PKCepsilon. ISO, PKCepsilon, ROS
319  2017 Pterostilbene exerts anticancer activity on non-small-cell lung cancer via activating endoplasmic reticulum stress. NSCLC, PT, ROS, RSV
320  2017 Rce1 expression in renal cell carcinoma and its regulatory effect on 786-O cell apoptosis through endoplasmic reticulum stress. ER, RCC, Rce1
321  2017 Regulation of mitochondrial function and endoplasmic reticulum stress by nitric oxide in pluripotent stem cells. NO
322  2017 Regulation of SREBP-2 intracellular trafficking improves impaired autophagic flux and alleviates endoplasmic reticulum stress in NAFLD. NAFLD, S1P, S2P, SREBP-2
323  2017 Regulation of the endoplasmic reticulum stress response and neuroprotective effects of acupuncture on brain injury caused by heroin addiction. EA, TUNEL, VTA
324  2017 Relationship between CHOP/GADD153 and unstable human carotid atherosclerotic plaque. AS, CEA, CHOP, GADD153, RT-PCR
325  2017 Relief of oxidative stress and cardiomyocyte apoptosis by using curcumin nanoparticles. Cur-NPs, PA, ROS
326  2017 Remifentanil postconditioning ameliorates histone H3 acetylation modification in H9c2 cardiomyoblasts after hypoxia/reoxygenation via attenuating endoplasmic reticulum stress. HDAC, IRI, RPC
327  2017 Role of Endoplasmic Reticulum Stress in Silica-induced Apoptosis in RAW264.7 Cells. 4-PBA, BiP, CHOP
328  2017 Roles of Endoplasmic Reticulum Stress in NECA-Induced Cardioprotection against Ischemia/Reperfusion Injury. GSK-3beta, I/R, mPTP
329  2017 Rosoloactone: A natural diterpenoid inducing apoptosis in human cervical cancer cells through endoplasmic reticulum stress and mitochondrial damage. ROS
330  2017 Salubrinal Alleviates Pressure Overload-Induced Cardiac Hypertrophy by Inhibiting Endoplasmic Reticulum Stress Pathway. ET-1, NRVMs, p-eIF2, PP1, TAC
331  2017 SYVN1, an ERAD E3 Ubiquitin Ligase, Is Involved in GABAAalpha1 Degradation Associated with Methamphetamine-Induced Conditioned Place Preference. ATS, CHOP, CPP, dSTR, ER, GABA, GRP78, METH, SYVN1
332  2017 Tacrolimus protects vascular endothelial cells from injuries caused by Ox-LDL by regulating endoplasmic reticulum stress. HUVEC, LDH, MTT, oxLDL, PCR, ROS, SOD
333  2017 Targeted inhibition of endoplasmic reticulum stress: New hope for renal fibrosis (Review). CKD
334  2017 Tauroursodeoxycholic acid (TUDCA) attenuates pressure overload-induced cardiac remodeling by reducing endoplasmic reticulum stress. BW, GO, HW, TAC, TUDCA, VEH
335  2017 TBHQ Alleviated Endoplasmic Reticulum Stress-Apoptosis and Oxidative Stress by PERK-Nrf2 Crosstalk in Methamphetamine-Induced Chronic Pulmonary Toxicity. MA, MA, tBHQ
336  2017 TGP attenuates endoplasmic reticulum stress and regulates the expression of thioredoxin-interacting protein in the kidneys of diabetic rats. CHOP, GRP78, p-eIF2alpha, p-PERK, TGP
337  2017 The involvement of endoplasmic reticulum stress response in immune dysfunction of dendritic cells after severe thermal injury in mice. DCs
338  2017 The reproductive toxicology of male SD rats after PM2.5 exposure mediated by the stimulation of endoplasmic reticulum stress. HE, PM, PM2.5, SD, TUNEL
339  2017 TSA protects H9c2 cells against thapsigargin-induced apoptosis related to endoplasmic reticulum stress-mediated mitochondrial injury. TG, UPR
340  2017 [Activating transcription factor 6-C/EBP homologous protein pathway mediates advanced glycated albumin-induced macrophage apoptosis]. AGE-alb, ATF6, LDH, siRNA
341  2017 [Activation of endoplasmic reticulum stress and its effect on osteogenic differentiation induced by micropit/nanotube topography]. ALP, ATF4, BiP, BM-MSC, ECM, MNT, PERK, qRT-PCR, SEM, TEM
342  2017 [Effects of HMGB1 inhibition on endoplasmic reticulum stress after myocardial ischemia/reperfusion injury in rats]. ELISA, HMGB1, I/R, PBS, RT-PCR, SD, TNF-alpha
343  2017 [Excessive endoplasmic reticulum stress mediates brain damage in hypoxia hypercapnia induced pulmonary hypertension rats]. 4-PBA, HHPH, TM
344  2017 [Over-expressed Bax inhibitor 1 (BI-1) inhibits apoptosis of hippocampal neurons via endoplasmic reticulum IRE1-JNK pathway in rats with subarachnoid hemorrhage]. BI-1, SAH
345  2017 [Protective effect of earthworm active ingredients against endoplasmic reticulum stress-induced acute liver injury in mice]. ATF4, CHOP, eIF2alpha, EWAs, GRP78, GSH-Px, MDA, PERK, SOD
346  2017 [Role of changes in sodium pump activity and endoplasmic reticulum stress in the ischemia/reperfusion induced injury of isolated hearts]. CK, I/R, I/R, LDH
347  2018 4-phenylbutyric acid attenuates endoplasmic reticulum stress-mediated apoptosis and protects the hepatocytes from intermittent hypoxia-induced injury. 4-PBA, IH, UPR
348  2018 Abeta1-42 induces cell damage via RAGE-dependent endoplasmic reticulum stress in bEnd.3 cells. AD, BBB, RAGE, siRNA
349  2018 Alleviation of endoplasmic reticulum stress protects against cisplatin-induced ovarian damage. 3-MA, ELISA, iTRAQ, POI, TUNEL
350  2018 alpha-Linolenic acid prevents hepatic steatosis and improves glucose tolerance in mice fed a high-fat diet. ALA, BiP, CA, CHOP, HA, HFD, HSP70, IL-1beta, IL-6, MCP-1, XBP1
351  2018 Anticancer effects of plant derived Anacardic acid on human breast cancer MDA-MB-231 cells. AA, Hsp90, TNBC
352  2018 Apigenin-7-O-beta-d-(-6″-p-coumaroyl)-glucopyranoside pretreatment attenuates myocardial ischemia/reperfusion injury via activating AMPK signaling. APG, CK, LDH, MI/R
353  2018 Apoptosis Induction by Iron Radiation via Inhibition of Autophagy in Trp53+/- Mouse Testes: Is Chronic Restraint-Induced Stress a Modifying Factor? CRIS, IR, PS
354  2018 Asiatic acid from Potentilla chinensis alleviates non-alcoholic fatty liver by regulating endoplasmic reticulum stress and lipid metabolism. AAPC, AMPK, FAS, HFD, LXRalpha, NAFLD, NF-kB, OA, SREBP-1c
355  2018 Berberine inhibits cardiac remodeling of heart failure after myocardial infarction by reducing myocardial cell apoptosis in rats. Sham group
356  2018 Bone Marrow-Derived Mesenchymal Stem Cells Protect Islet Grafts Against Endoplasmic Reticulum Stress-Induced Apoptosis During the Early Stage After Transplantation. BMSCs
357  2018 Bufalin suppresses endometriosis progression by inducing pyroptosis and apoptosis. ER, SRC
358  2018 Cell Stress Signaling Cascades Regulating Cell Fate. ---
359  2018 Changes of MODY signal pathway genes in the endoplasmic reticulum stress in INS-1-3 cells. DGE, GO, GSIS, MODY, MTT, PA, RT-PCR, TG, TM
360  2018 Cleavage of caspase-12 at Asp94, mediated by endoplasmic reticulum stress (ERS), contributes to stretch-induced apoptosis of myoblasts. CMS, TC-casp12-D94
361  2018 Compound K Induces Endoplasmic Reticulum Stress and Apoptosis in Human Liver Cancer Cells by Regulating STAT3. HCC
362  2018 Connexin32 plays a crucial role in ROS-mediated endoplasmic reticulum stress apoptosis signaling pathway in ischemia reperfusion-induced acute kidney injury. AKI, Cx32, I/R, ROS
363  2018 Correlation of increased Th17/Treg cell ratio with endoplasmic reticulum stress in chronic kidney disease. CHOP, CKD, GRP78, HD, PD, Treg
364  2018 Creatine phosphate disodium salt protects against Dox-induced cardiotoxicity by increasing calumenin. CP, DOX, NRC
365  2018 Crosstalk Between Nuclear Glucose-Regulated Protein 78 and Tumor Protein 53 Contributes to the Lipopolysaccharide Aggravated Apoptosis of Endoplasmic Reticulum Stress-Responsive Porcine Intestinal Epithelial Cells. GRP78, LPSs
366  2018 Cucurbitacin I induces cancer cell death through the endoplasmic reticulum stress pathway. IRE1alpha, PERK
367  2018 Developmental toxicity induced by PM2.5 through endoplasmic reticulum stress and autophagy pathway in zebrafish embryos. ---
368  2018 Dexmedetomidine Ameliorates Acute Stress-Induced Kidney Injury by Attenuating Oxidative Stress and Apoptosis through Inhibition of the ROS/JNK Signaling Pathway. DEX, NE, ROS
369  2018 Differentially expressed genes of HepG2 cells treated with gecko polypeptide mixture. DEGs, GPM, HCC, ROS
370  2018 Effect and mechanisms of celastrol on the apoptosis of HOS osteosarcoma cells. ---
371  2018 Effect of CXCR4 on Apoptosis in Osteosarcoma Cells via the PI3K/Akt/NF-kappabeta Signaling Pathway. ---
372  2018 Effects of calpain inhibitor on the apoptosis of hepatic stellate cells induced by calcium ionophore A23187. ALLN, ER, HSCs
373  2018 Effects of endoplasmic reticulum stress on autophagy and apoptosis of human leukemia cells via inhibition of the PI3K/AKT/mTOR signaling pathway. CHOP, MDC, mTOR, PI3K
374  2018 Effects of glutamine on intestinal mucus barrier after burn injury. DAO, Gln, IMBF, ITF
375  2018 Effects of resveratrol pretreatment on endoplasmic reticulum stress and cognitive function after surgery in aged mice. NF-kappaB, POCD, SIRT1, UPR
376  2018 EndophilinA2 protects against angiotensin II-induced cardiac hypertrophy by inhibiting angiotensin II type 1 receptor trafficking in neonatal rat cardiomyocytes. Ang II, AT1R, EndoA2, NRCMs, qPCR
377  2018 Endoplasmic reticulum stress activation in adipose tissue induces metabolic syndrome in individuals with familial partial lipodystrophy of the Dunnigan type. FPLD
378  2018 Endoplasmic reticulum stress contributes to the pathogenesis of stress urinary incontinence in postmenopausal women. ATF4, ATF6, Bcl-2, CHOP, IRE1, PERK, SUI
379  2018 Establishment of a novel non‑alcoholic fatty liver disease model using cholesterol‑fed rabbits with reference to the potential role of endoplasmic reticulum stress. HCD, NAFLD
380  2018 Estrogen and propofol combination therapy inhibits endoplasmic reticulum stress and remarkably attenuates cerebral ischemia-reperfusion injury and OGD injury in hippocampus. CHOP, combination group, DSMO, estrogen group, GRP78, MCAO, OGD, OPS, TTC
381  2018 Excessive endoplasmic reticulum stress and decreased neuroplasticity-associated proteins in prefrontal cortex of obese rats and the regulatory effects of aerobic exercise. ---
382  2018 FGF21 attenuates hypoxia‑induced dysfunction and apoptosis in HPAECs through alleviating endoplasmic reticulum stress. BiP, FGF, HPAECs, NO, PAH, PERK
383  2018 Gambogic acid induces cell apoptosis through endoplasmic reticulum stress triggered inhibition of Akt signaling pathways in extranodal NK/T-cell lymphoma cells. ENKTL, GA
384  2018 Gastrodin Ameliorates Cognitive Dysfunction in Diabetes Rat Model via the Suppression of Endoplasmic Reticulum Stress and NLRP3 Inflammasome Activation. BDNF, DM, GAS, HDL-C, HE, LDL-C, TC, TG
385  2018 Gga-let-7f-3p promotes apoptosis in selenium deficiency-induced skeletal muscle by targeting selenoprotein K. miRNAs, NAC, SELENOK
386  2018 Ghrelin ameliorates acute lung injury induced by oleic acid via inhibition of endoplasmic reticulum stress. ALI, HE, OA, TM
387  2018 Glibenclamide exacerbates adriamycin-induced cardiotoxicity by activating oxidative stress-induced endoplasmic reticulum stress in rats. ADR, GLI
388  2018 GSK-3beta inhibition confers cardioprotection associated with the restoration of mitochondrial function and suppression of endoplasmic reticulum stress in sevoflurane preconditioned rats following ischemia/reperfusion injury. CHOP, I/R, mPTP
389  2018 High Mobility Group B-1 (HMGB-1) Promotes Apoptosis of Macrophage-Derived Foam Cells by Inducing Endoplasmic Reticulum Stress. CHOP, DHE, HMGB-1, oxLDL, ROS, TUNEL
390  2018 Honokiol induces apoptosis and autophagy via the ROS/ERK1/2 signaling pathway in human osteosarcoma cells in vitro and in vivo. ERK, GRP, HNK, ROS
391  2018 HSP90 inhibitor 17-AAG prevents apoptosis of cardiomyocytes via miR-93-dependent mitigation of endoplasmic reticulum stress. Hsp90
392  2018 Hydrogen-rich saline protects against small-scale liver ischemia-reperfusion injury by inhibiting endoplasmic reticulum stress. HRS, IRI
393  2018 Hyperbaric oxygen treatment sensitizes gastric cancer cells to melatonin-induced apoptosis through multiple pathways. ---
394  2018 Ibrutinib improves the development of acute lymphoblastic leukemia by activating endoplasmic reticulum stress-induced cell death. ALL, TUDCA
395  2018 Immunocompetence and mechanism of the DRibble-DCs vaccine for oral squamous cell carcinoma. DRibble-DCs
396  2018 Inhibition of cFLIP overcomes acquired resistance to sorafenib via reducing ER stress‑related autophagy in hepatocellular carcinoma. HCC
397  2018 Inhibition of endoplasmic reticulum stress by 4-phenylbutyric acid prevents vital organ injury in rat acute pancreatitis. 4-PBA, AP
398  2018 Inhibition of endoplasmic reticulum stress by intermedin1-53 attenuates angiotensin II-induced abdominal aortic aneurysm in ApoE KO Mice. AAA, AMP, Ang II, ATF4, eIF2a, GRP94, IMD, Tau
399  2018 Inhibition of p38 mitogen-activated protein kinase exerts a hypoglycemic effect by improving beta cell function via inhibition of beta cell apoptosis in db/db mice. MAPK
400  2018 Interplay between Endoplasmic Reticular Stress and Survivin in Colonic Epithelial Cells. 4PBA, IAP, IF, IHC, PARP, UPR
401  2018 Involvement of miR-455 in the protective effect of H2S against chemical hypoxia-induced injury in BEAS-2B cells. CALR, CHOP
402  2018 Long noncoding ribonucleic acid NKILA induces the endoplasmic reticulum stress/autophagy pathway and inhibits the nuclear factor-k-gene binding pathway in rats after intracerebral hemorrhage. ICH, lncRNAs, NF-kB, siRNA
403  2018 Low-frequency ultrasound enhances chemotherapy sensitivity and induces autophagy in PTX-resistant PC-3 cells via the endoplasmic reticulum stress-mediated PI3K/Akt/mTOR signaling pathway. ATG5, PTX, SDT, TEM
404  2018 Lutein and Zeaxanthin Isomers Protect against Light-Induced Retinopathy via Decreasing Oxidative and Endoplasmic Reticulum Stress in BALB/cJ Mice. ATF4, ERG, Nrf2, OS, p-JNK, p-PERK
405  2018 Lutein and Zeaxanthin Isomers Reduce Photoreceptor Degeneration in the Pde6b rd10 Mouse Model of Retinitis Pigmentosa. ERG, ERp29, L-Z, OS, RP
406  2018 Lycium barbarum polysaccharide arbitrates palmitate-induced apoptosis in MC3T3‑E1 cells through decreasing the activation of ERS‑mediated apoptosis pathway. LBP, PA
407  2018 Lycium barbarum polysaccharide improves the development of mouse oocytes vitrified at the germinal vesicle stage. COCs, LBP
408  2018 Lycium barbarum polysaccharide prevents cisplatin-induced MLTC-1 cell apoptosis and autophagy via regulating endoplasmic reticulum stress pathway. LBP
409  2018 Mechanism of Astragalus polysaccharides in attenuating insulin resistance in Rats with type 2 diabetes mellitus via the regulation of liver microRNA‑203a‑3p. APS, CHOP, GK, GRP, IR, mi, miR, p-JNK, T2DM
410  2018 Melatonin prevents senescence of canine adipose-derived mesenchymal stem cells through activating NRF2 and inhibiting ER stress. ADMSCs, cADMSCs, ERAD, SASP
411  2018 Methotrexate remediates spinal cord injury in vivo and in vitro via suppression of endoplasmic reticulum stress-induced apoptosis. CHOP, GRP, MTX, SCI, TG
412  2018 Metoprolol, N-Acetylcysteine, and Escitalopram Prevents Chronic Unpredictable Mild Stress-Induced Depression by Inhibition of Endoplasmic Reticulum Stress. CHOP, CUMS, ESC, GRP78, MDD, MET, NAC
413  2018 miR-26 Induces Apoptosis and Inhibits Autophagy in Non-small Cell Lung Cancer Cells by Suppressing TGF-beta1-JNK Signaling Pathway. LC3, NSCLC
414  2018 MiR-410 Acts as a Tumor Suppressor in Estrogen Receptor-Positive Breast Cancer Cells by Directly Targeting ERLIN2 via the ERS Pathway. EMT, ER, ERLIN2, miRNAs
415  2018 Neuritin Attenuates Neuronal Apoptosis Mediated by Endoplasmic Reticulum Stress In Vitro. GRP78, OGD
416  2018 New Insights into the Role of Endoplasmic Reticulum Stress in Breast Cancer Metastasis. ER
417  2018 Optimized postconditioning algorithm protects liver graft after liver transplantation in rats. IRI, MDA, MPO, PostC
418  2018 Overexpression of septin-7 inhibits melatonin-induced cell apoptosis in human fetal osteoblastic cells via suppression of endoplasmic reticulum stress. hFOB, SEPT7
419  2018 Oxidative Stress Mediates Microcystin-LR-Induced Endoplasmic Reticulum Stress and Autophagy in KK-1 Cells and C57BL/6 Mice Ovaries. MC-LR, ROS
420  2018 Palmitic acid, but not high-glucose, induced myocardial apoptosis is alleviated by N‑acetylcysteine due to attenuated mitochondrial-derived ROS accumulation-induced endoplasmic reticulum stress. Bax, Bcl-2, CHOP, DCM, eIF2alpha, GRP78, IRE1alpha, NAC, NADPH, NOX4, NRCMs, PERK, ROS, XBP1
421  2018 Periostin has a protective role in melatonin‑induced cell apoptosis by inhibiting the eIF2alpha‑ATF4 pathway in human osteoblasts. ATF, CHOP, eIF2alpha, GRP, POSTN, XBP1
422  2018 Postconditioning with sevoflurane ameliorates spatial learning and memory deficit via attenuating endoplasmic reticulum stress induced neuron apoptosis in a rat model of hemorrhage shock and resuscitation. CHOP, GRP78, MWM, TUNEL
423  2018 Preventive effects of total saponins of Panax japonicus on fatty liver fibrosis in mice. alpha-SMA, CHOP, Coll, HF, JNK, NAFLD, p-JNK, RT-PCR, SPJ, TIMP
424  2018 Proanthocyanidins Protect Epithelial Cells from Zearalenone-Induced Apoptosis via Inhibition of Endoplasmic Reticulum Stress-Induced Apoptosis Pathways in Mouse Small Intestines. caspase-12, CHOP, GSH-Px, JNK, MDA, PCs, SOD, ZEA
425  2018 Progesterone inhibited endoplasmic reticulum stress associated apoptosis induced by interleukin-1beta via the GRP78/PERK/CHOP pathway in BeWo cells. CHOP, GRP78, IL, PE, PERK
426  2018 Protective effect of exogenous hydrogen sulfide on pulmonary artery endothelial cells by suppressing endoplasmic reticulum stress in a rat model of chronic obstructive pulmonary disease. AI, CHOP, COPD, FEV0.3, FVC, GRP78, IOD, LPS, PAECs
427  2018 Protective effect of miR378* on doxorubicin-induced cardiomyocyte injury via calumenin. DOX
428  2018 Protective Effects and Target Network Analysis of Ginsenoside Rg1 in Cerebral Ischemia and Reperfusion Injury: A Comprehensive Overview of Experimental Studies. ERK, G-Rg1, HMGB1, JNK, NMDA, RAGE, rt-PA
429  2018 Protective effects of a G. lucidum proteoglycan on INS-1 cells against IAPP-induced apoptosis via attenuating endoplasmic reticulum stress and modulating CHOP/JNK pathways. ATF6, CHOP, FYGL, IAPP, IRE1alpha, JNK, PKR
430  2018 Protective effects of circulating microvesicles derived from ischemic preconditioning on myocardial ischemia/reperfusion injury in rats by inhibiting endoplasmic reticulum stress. EMVs, I/R, LAD, MVs, PMVs
431  2018 Protein tyrosine phosphatase 1B regulates endothelial endoplasmic reticulum stress; role in endothelial dysfunction. NO, PERK, PTP1B
432  2018 Quercetin protects against intestinal barrier disruption and inflammation in acute necrotizing pancreatitis through TLR4/MyD88/p38 MAPK and ERS inhibition. ANP, DAO, MPO, TEM, ZO-1
433  2018 Rab6A GTPase contributes to phenotypic modulation in pulmonary artery smooth muscle cells under hypoxia. GRP78, rPASMCs, VIM
434  2018 Recombinant Newcastle disease virus expressing human IFN-lamda1 (rL-hIFN-lamda1)-induced apoptosis of A549 cells is connected to endoplasmic reticulum stress pathways. rL-hIFN-lamda1
435  2018 Role of autophagy in a model of obesity: A long‑term high fat diet induces cardiac dysfunction. HFD, NC, PAP
436  2018 Role of intestinal trefoil factor in protecting intestinal epithelial cells from burn-induced injury. BBMVs, ITF
437  2018 Role of X-Box Binding Protein-1 in Fructose-Induced De Novo Lipogenesis in HepG2 Cells. ACC, ChREBP, FAS, SCD-1, SREBP-1c, TUDCA, XBP1
438  2018 Roles of endoplasmic reticulum stress and autophagy on H2O2‑induced oxidative stress injury in HepG2 cells. ROS, SAL, TM
439  2018 Sodium butyrate mitigates type 2 diabetes by inhibiting PERK-CHOP pathway of endoplasmic reticulum stress. CHOP, HDAC, p-eIF2alpha, p-PERK
440  2018 Stellate ganglion block ameliorates vascular calcification by inhibiting endoplasmic reticulum stress. ALP, SGB, VC, VSMC
441  2018 Strontium Alleviates Endoplasmic Reticulum Stress in a Nonalcoholic Fatty Liver Disease Model. ATF6, GRP78, HFD, IRE1, LDL-C, NAFLD, SCAP, SREBP-1c, TC, TG
442  2018 Synergistic neuroprotective effects of Geniposide and ursodeoxycholic acid in hypoxia-reoxygenation injury in SH-SY5Y cells. I/R, LDH, OGD/R, qPCR, ROS, TUDCA
443  2018 The cryoprotectant trehalose could inhibit ERS-induced apoptosis by activating autophagy in cryoprotected rat valves. CHOP, DMSO, GRP78
444  2018 The intervention of enalapril maleate and folic acid tablet on the expressions of the GRP78 and CHOP and vascular remodeling in the vascular smooth muscle cells of H-hypertensive rats with homocysteine. Hcy
445  2018 Titanium dioxide nanoparticles induce mouse hippocampal neuron apoptosis via oxidative stress- and calcium imbalance-mediated endoplasmic reticulum stress. NAC, PI, ROS
446  2018 Total Saponins of Aralia Elata (Miq) Seem Alleviate Calcium Homeostasis Imbalance and Endoplasmic Reticulum Stress-Related Apoptosis Induced by Myocardial Ischemia/Reperfusion Injury. CaN, CHOP, CK, HE, LDH, MDA, MIRI, SD, SOD, TTC
447  2018 Toxoplasma gondii dense granule protein 15 induces apoptosis in choriocarcinoma JEG-3 cells through endoplasmic reticulum stress. ASK1, CHOP, GRA15, GRA15, JNK, pEGFP, TRAF2, XBP1
448  2018 TRPM7 channels play a role in high glucose-induced endoplasmic reticulum stress and neuronal cell apoptosis. CHOP, HG, iNOS, TRPM7
449  2018 Zingiber officinale extract administration diminishes steroyl-CoA desaturase gene expression and activity in hyperlipidemic hamster liver by reducing the oxidative and endoplasmic reticulum stress. ACC, CYP7A1, GIN, HL, MPO, NEFA, PON1, PPARgamma, SCD, TBARS, TG
450  2018 [Anti-lung cancer mechanisms of diterpenoid tanshinone via endoplasmic reticulum stress-mediated apoptosis signal pathway]. DT
451  2018 [Effect of Astragalus injection on cardiomyocyte apoptosis, endoplasmic reticulum stress and expression of connexin in cardiomyopathy rats induced by adriamycin]. ADR, CHOP, GRP78, LVEDD, LVEF, LVESD
452  2018 [Effect of naringin on oxidative stress and endoplasmic reticulum stress in diabetic cardiomyopathy]. caspase 12, CHOP, CON, GRP78, MDA, NAR, SOD, STZ, T1DR
453  2018 [Effects of excessive endoplasmic reticulum stress on lung ischemia/reperfusion induced myocardial injury in mice]. 4-PBA, CHOP, CK-MB, GRP78, I/R, LDH, p-JNK, TM
454  2018 [Effects of rosuvastatin in homocysteine induced mouse vascular smooth muscle cell dedifferentiation and endoplasmic reticulum stress and its mechanisms]. 4-PBA, Hcy, mTOR, P70S6K, VSMCs
455  2018 [Electroacupuncture Combined with Intracerebral Injection of VEGF Improves Neurological Dysfunction Possibly by Down-regulating Expression of Endoplasmic Reticulum Stress Related Proteins ATF 6, etc. in Cerebral Ischemia-reperfusion Injury Rats]. CHOP, CIRI, EA, IRE 1, mNSS, VEGF, WB, XBP1
456  2018 [High mobility group box 1 contributes to the endoplasmic reticulum stress of liver in rats with trauma]. AST, CHOP, EP, GRP78, HE, HMGB1, IRE1alpha, SB, SD
457  2018 [Interaction between glycogen synthase kinase-3beta and endoplasmic reticulum stress is involved in high glucose-induced injury in human umbilical vein endothelial cells]. GSK-3beta, HG, HUVECs, MMP, Rh123, ROS
458  2018 [Mild hypothermia combined with hydrogen sulfide alleviates hippocampal endoplasmic reticulum stress after global cerebral ischemia-reperfusion]. GRP78, I/R
459  2018 [Protective effect of earthworm active ingredients against endoplasmic reticulum stress induced L-02 hepatocyte apoptosis]. EWAs, TM
460  2018 [Protective effect of Wuzi Yanzong recipe on testicular germ cell apoptosis in natural ageing rats through endoplasmic reticulum stress]. ---
461  2018 [Role of endoplasmic reticulum stress-induced apoptosis of trophoblasts in intrahepatic cholestasis during pregnancy]. DCA, ICP
462  2018 [The role of endoplasmic reticulum stress in pulmonary hypertension in rat induced by chronic hypoxia and hypercapnia]. 4-PBA, alpha-SMA, caspase-12, CHOP, HH, JNK, LA/TA, mCAP, mPAP, TM, WA/TA
463  2019 4-Phenylbutyric Acid Attenuates Endoplasmic Reticulum Stress-Mediated Intestinal Epithelial Cell Apoptosis in Rats with Severe Acute Pancreatitis. 4-PBA, 4-PBA group, IECs, SAP, STC
464  2019 Acetaldehyde Induces Neurotoxicity In Vitro via Oxidative Stress- and Ca2+ Imbalance-Mediated Endoplasmic Reticulum Stress. ADE, NAC, ROS
465  2019 Apelin-13 protects dopaminergic neurons in MPTP-induced Parkinson's disease model mice through inhibiting endoplasmic reticulum stress and promoting autophagy. MPTP, PD, SNpc, TH
466  2019 Astragaloside IV ameliorates endoplasmic reticulum stress‑induced apoptosis of Abeta25‑35‑treated PC12 cells by inhibiting the p38MAPK signaling pathway. AD, ASTIV, MAPK, MDA, ROS, SOD
467  2019 Atorvastatin reduces alcohol-induced endoplasmic reticulum stress in AC16 cardiomyocytes. TG
468  2019 Bilirubin Attenuates ER Stress-Mediated Inflammation, Escalates Apoptosis and Reduces Proliferation in the LS174T Colonic Epithelial Cell Line. UCB
469  2019 Both Bupivacaine and Levobupivacaine inhibit colon cancer cell growth but not melanoma cells in vitro. ---
470  2019 Chronic intermittent hypoxia accelerates liver fibrosis in rats with combined hypoxia and nonalcoholic steatohepatitis via angiogenesis rather than endoplasmic reticulum stress. HIF-1alpha, NASH
471  2019 CircRNA-012091/PPP1R13B-Mediated Lung Fibrotic Response in Silicosis via ER Stress and Autophagy. ---
472  2019 Death-associated protein kinase 3 deficiency alleviates vascular calcification via AMPK-mediated inhibition of endoplasmic reticulum stress. AMPK, CKD, DAPK3, VC, VSMC
473  2019 Deregulation of long noncoding RNA (TUG1) contributes to excessive podocytes apoptosis by activating endoplasmic reticulum stress in the development of diabetic nephropathy. CHOP, DN, HG, lncRNA, PGC-1alpha, siRNA
474  2019 DL-3-n-butylphthalide alleviates vascular cognitive impairment by regulating endoplasmic reticulum stress and the Shh/Ptch1 signaling-pathway in rats. CCH, NBP, Ptch1, Shh, VD
475  2019 Effects of insulin-like growth factor-1 on endoplasmic reticulum stress and autophagy in rat gastric smooth muscle cells cultured at different glucose concentrations in vitro. DGP, GRP78, IGF-1, LC3, NC
476  2019 Endoplasmic reticulum stress affected chondrocyte apoptosis in femoral head necrosis induced by glucocorticoid in broilers. FHN, MP
477  2019 Endoplasmic Reticulum Stress Induces Macrophages to Produce IL-1beta During Mycobacterium bovis Infection via a Positive Feedback Loop Between Mitochondrial Damage and Inflammasome Activation. AIM2, IL, NLRP3, ROS
478  2019 Endoplasmic reticulum stress triggers Xanthoangelol-induced protective autophagy via activation of JNK/c-Jun Axis in hepatocellular carcinoma. BafA1, HCC, XAG
479  2019 Exercise protects against diabetic cardiomyopathy by the inhibition of the endoplasmic reticulum stress pathway in rats. CHOP, cTnI, DM, GRP78, SD, STZ
480  2019 Fibroblast Growth Factor 21 Attenuates Vascular Calcification by Alleviating Endoplasmic Reticulum Stress Mediated Apoptosis in Rats. FGF21, VC
481  2019 Ghrelin attenuates UUO-induced renal fibrosis via attenuation of Nlrp3 inflammasome and endoplasmic reticulum stress. CKD, IHC, NLRP3, UUO
482  2019 Hepatotoxicity Induced by Isoniazid-Lipopolysaccharide through Endoplasmic Reticulum Stress, Autophagy, and Apoptosis Pathways in Zebrafish. 4-PBA, AST, COX-2, HE, IL-1b, LFABP, LPS, TNF-beta
483  2019 Hispidulin induces ER stress-mediated apoptosis in human hepatocellular carcinoma cells in vitro and in vivo by activating AMPK signaling pathway. HCC, UPR
484  2019 Icariin protects vascular endothelial cells from oxidative stress through inhibiting endoplasmic reticulum stress. ATF4, DTT, eIF2alpha, GRP78, GSH-Px, ICA, SOD
485  2019 Icariside II prevents hypertensive heart disease by alleviating endoplasmic reticulum stress via the PERK/ATF-4/CHOP signalling pathway in spontaneously hypertensive rats. SHRs
486  2019 IL-17A contributes to HSV1 infection-induced acute lung injury in a mouse model of pulmonary fibrosis. AE, ALI, BALF, BLM, HSV-1, IPF, WT
487  2019 Induction of Endoplasmic Reticulum Stress by Cadmium and Its Regulation on Nrf2 Signaling Pathway in Kidneys of Rats. Cd, TUDCA
488  2019 Inhibition of Brd4 alleviates renal ischemia/reperfusion injury-induced apoptosis and endoplasmic reticulum stress by blocking FoxO4-mediated oxidative stress. AKI, I/R
489  2019 Inhibition of endoplasmic reticulum stress protected DOCA-salt hypertension-induced vascular dysfunction. Bcl-2, DOCA, EGFR, NO, p-PERK, TUDCA
490  2019 Isorhamnetin protects against bleomycin-induced pulmonary fibrosis by inhibiting endoplasmic reticulum stress and epithelial-mesenchymal transition. EMT, HBECs, IHC, Isor, TGF
491  2019 Mechanism of isoniazid-induced hepatotoxicity in zebrafish larvae: Activation of ROS-mediated ERS, apoptosis and the Nrf2 pathway. AST, CAT, GPx, MDA, ROS
492  2019 MiR-451a suppressing BAP31 can inhibit proliferation and increase apoptosis through inducing ER stress in colorectal cancer. CRC
493  2019 Monosialoganglioside protects against bupivacaine-induced neurotoxicity caused by endoplasmic reticulum stress in rats. ---
494  2019 MTORC1 coordinates the autophagy and apoptosis signaling in articular chondrocytes in osteoarthritic temporomandibular joint. FFSS, OA, TMJ, UAC
495  2019 PI3-kinase/Akt pathway-regulated membrane transportation of acid-sensing ion channel 1a/Calcium ion influx/endoplasmic reticulum stress activation on PDGF-induced HSC Activation. ASIC1a, HSC
496  2019 Porcine circovirus type 2 ORF5 protein induces endoplasmic reticulum stress and unfolded protein response in porcine alveolar macrophages. ATF6, Cap, IRE1, ORF5, PAMs, PCV2, PCVD, TEM, UPR
497  2019 Prosurvival roles mediated by the PERK signaling pathway effectively prevent excessive endoplasmic reticulum stress-induced skeletal muscle loss during high-stress conditions of hibernation. GRP78, IBA, LT, p-eIF2alpha
498  2019 Protective effect of Barbaloin in a rat model of myocardial ischemia reperfusion injury through the regulation of the CNPY2‑PERK pathway. Bar, CHOP, CNPY2, MIRI, PERK
499  2019 Protective effect of Wuzi Yanzong recipe on testicular dysfunction through inhibition of germ cell apoptosis in ageing rats via endoplasmic reticulum stress. WZ
500  2019 Pterostilbene exerts a protective effect via regulating tunicamycin-induced endoplasmic reticulum stress in mouse preimplantation embryos. PTS, TM
501  2019 Regulation of P300 and HDAC1 on endoplasmic reticulum stress in isoniazid-induced HL-7702 hepatocyte injury. ADLI
502  2019 Riluzole induces AR degradation via endoplasmic reticulum stress pathway in androgen-dependent and castration-resistant prostate cancer cells. AD, AR, AR-V7, CR, PCa
503  2019 Role of reciprocal interaction between autophagy and endoplasmic reticulum stress in apoptosis of human bronchial epithelial cells induced by cigarette smoke extract. COPD, CSE, HBE, qRT-PCR
504  2019 Sodium butyrate and panobinostat induce apoptosis of chronic myeloid leukemia cells via multiple pathways. CML, HDACi
505  2019 The IRE1alpha-XBP1 pathway function in hypoxia-induced pulmonary vascular remodeling, is upregulated by quercetin, inhibits apoptosis and partially reverses the effect of quercetin in PASMCs. HPH, PASMCs, UPR
506  2019 The protective microRNA-199a-5p-mediated unfolded protein response in hypoxic cardiomyocytes is regulated by STAT3 pathway. ATF6, ChIP, IL, pSTAT3, STAT3
507  2019 Unfolded Protein Response Pathways Correlatively Modulate Endoplasmic Reticulum Stress Responses in Rat Retinal Muller Cells. ATF4, ATF6, DR, GRP78, IRE1, PERK, UPR, VEGF, XBP1
508  2019 Upregulation of Nuclear Factor IA Suppresses Oxidized Low-Density Lipoprotein-Induced Endoplasmic Reticulum Stress and Apoptosis in Human Umbilical Vein Endothelial Cells. HUVECs, LDH, NFIA, oxLDL, ROS
509  2019 Xanthatin induces apoptosis by activating endoplasmic reticulum stress in hepatoma cells. HCC, UPR
510  2019 [Interventional effect of bicyclol on isoniazid-induced liver injury in rats and the expression of glucose-regulated protein 78, and growth arrest and DNA-damage-inducible gene 153]. AST, GRP78
511  2019 [Progress of researches on acupuncture treatment of diseases by regulating endoplasmic reticulum stress]. ATF4, CHOP, eIF2alpha, GRP78, p-ERK, UPR