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Abbreviation : Sal B
Long Form : salvianolic acid B
No. Year Title Co-occurring Abbreviation
1998 Increase of vitamin E content in LDL and reduction of atherosclerosis in cholesterol-fed rabbits by a water-soluble antioxidant-rich fraction of Salvia miltiorrhiza. SM
2000 Salvianolic acid B protects brain against injuries caused by ischemia-reperfusion in rats. ATP, LA, MDA, NIM, SOD
2000 Salvianolic acid B protects the memory functions against transient cerebral ischemia in mice. ---
2000 [Effects of salvianolic acid B on beta-amyloid peptide neurotoxicity of primary cultured fetal rat cortical neurons]. Glu, LDH, NO, NOS, SNP
2001 Salvianolic acid B attenuates VCAM-1 and ICAM-1 expression in TNF-alpha-treated human aortic endothelial cells. E-selectin, HAECs, ICAM-1, NF-kappaB, TNF-alpha, VCAM-1
2003 Crude extract of Salvia miltiorrhiza and salvianolic acid B enhance in vitro angiogenesis in murine SVR endothelial cell line. MMP-2, RT-PCR, SM, VEGF
2003 Salvianolic acid B enhances in vitro angiogenesis and improves skin flap survival in Sprague-Dawley rats. FNA
2005 Aqueous extract of Salvia miltiorrhiza attenuates increased endothelial permeability induced by tumor necrosis factor-alpha. DSS, ERK, ESM, VE, VEGF
2006 In vitro protective effects of salvianolic acid B on primary hepatocytes and hepatic stellate cells. HSCs, MDA, ROS, TGF-beta1
10  2006 Salvianolic acid B attenuates cyclooxygenase-2 expression in vitro in LPS-treated human aortic smooth muscle cells and in vivo in the apolipoprotein-E-deficient mouse aorta. COX, HASMCs, LPS
11  2006 Salvianolic acid B, an antioxidant from Salvia miltiorrhiza, prevents Abeta(25-35)-induced reduction in BPRP in PC12 cells. BPRP, ROS
12  2006 The preventive effect of salvianolic acid B on malignant transformation of DMBA-induced oral premalignant lesion in hamsters. DMBA, SCC, SM
13  2006 [Comparison of the inhibitory activities of salvianolic acid B and Ginkgo biloba extract EGb 761 on neurotoxicity of beta-amyloid peptide]. betaAP, ROS, ThT
14  2007 Salvianolic acid B attenuates MMP-2 and MMP-9 expression in vivo in apolipoprotein-E-deficient mouse aorta and in vitro in LPS-treated human aortic smooth muscle cells. HASMCs, LPS
15  2007 Salvianolic acid B inhibits hydrogen peroxide-induced endothelial cell apoptosis through regulating PI3K/Akt signaling. rCMECs
16  2007 Salvianolic acid B modulates hemostasis properties of human umbilical vein endothelial cells. HUVECs, PAI-1, SM
17  2007 Structural characterization of metabolites of salvianolic acid B from Salvia miltiorrhiza in normal and antibiotic-treated rats by liquid chromatography-mass spectrometry. ---
18  2007 Study on the mechanisms of an extract of Salvia miltiorrhiza on the regulation of permeability of endothelial cells exposed to tumour necrosis factor-alpha. DSS, ESM, TNF-alpha
19  2007 The effect of the major components of Salvia Miltiorrhiza Bunge on bone marrow cells. ALP, PCA, SMB, TS
20  2007 [Effect of salvianolic acid B on brain energy metabolism and hydrocephalus of cerebral ischemia in mice at different time]. EC, Lac, Nim, PCr, SHAM
21  2007 [Effect of salvianolic acid B on neural cells damage and neurogenesis after brain ischemia-reperfusion in rats]. I/R, MCAO, SGZ, SVZ
22  2008 Cardioprotective effect of salvianolic acid B on large myocardial infarction mediated by reversing upregulation of leptin, endothelin pathways, and abnormal expression of SERCA2a, phospholamban in rats. ET-ROS, MI, PLB, SERCA2a
23  2008 Comparison of cardioprotective effects of salvianolic acid B and benazepril on large myocardial infarction in rats. LV, MI, mRNA, VEGF
24  2008 Comparison of cardioprotective effects using salvianolic acid B and benazepril for the treatment of chronic myocardial infarction in rats. LV, MI, mRNA, VEGF
25  2008 Inhibitory effects of salvianolic acid B on the high glucose-induced mesangial proliferation via NF-kappaB-dependent pathway. ---
26  2008 Pharmacokinetic interaction between tanshinones and polyphenolic extracts of salvia miltinorrhiza BUNGE after intravenous administration in rats. AUC, TSIIA
27  2008 Salvianolic acid B inhibits Abeta fibril formation and disaggregates preformed fibrils and protects against Abeta-induced cytotoxicty. AD
28  2008 Salvianolic acid B promotes survival of transplanted mesenchymal stem cells in spinal cord-injured rats. BBB, MSC, PBS, SCI
29  2009 Isolation and purification of salvianolic acid A and salvianolic acid B from Salvia miltiorrhiza by high-speed counter-current chromatography and comparison of their antioxidant activity. DPPH, HSCCC, Sal A
30  2009 Preventive effects of salvianolic acid B on transforming growth factor-beta1-induced epithelial-to-mesenchymal transition of human kidney cells. EMT, SMA, TGF
31  2009 Protective effect of salvianolic acid B on chronic pancreatitis induced by trinitrobenzene sulfonic acid solution in rats. MDA
32  2009 Salvianolic acid B in vitro inhibited matrix metalloproteinases-1, -2, and -9 activities. APMA, MMPs, PMN
33  2009 Salvianolic acid B inhibits growth of head and neck squamous cell carcinoma in vitro and in vivo via cyclooxygenase-2 and apoptotic pathways. COX-2, HNSCC
34  2009 Salvianolic acid B protects human endothelial cells from oxidative stress damage: a possible protective role of glucose-regulated protein 78 induction. ATF4, ER, GRP78, HUVECs, PKR, RT-PCR
35  2009 The strategy of combined ischemia preconditioning and salvianolic acid-B pretreatment to prevent hepatic ischemia-reperfusion injury in rats. EC, IPC, IRI, MDA
36  2010 Anti-inflammatory activity of salvianolic acid B in microglia contributes to its neuroprotective effect. IFN, IL-1beta, iNOS, LPS, NO, ROS, TNF-alpha
37  2010 Combination effects of salvianolic acid B with low-dose celecoxib on inhibition of head and neck squamous cell carcinoma growth in vitro and in vivo. COX-2, HNSCC
38  2010 Pharmacokinetic interactions induced by content variation of major water-soluble components of Danshen preparation in rats. CL, DSS, PA, PAL, Sal A
39  2010 Salvianolic acid B attenuates hepatocyte apoptosis by regulating mediators in death receptor and mitochondrial pathways. ---
40  2010 Salvianolic acid B prevents epithelial-to-mesenchymal transition through the TGF-beta1 signal transduction pathway in vivo and in vitro. EMT, MMP-2, RIF
41  2010 Salvianolic acid B protects SH-SY5Y neuroblastoma cells from 1-methyl-4-phenylpyridinium-induced apoptosis. PD
42  2010 The Arabidopsis PAP1 transcription factor plays an important role in the enrichment of phenolic acids in Salvia miltiorrhiza. ---
43  2010 The effect of salvianolic acid B combined with laminar shear stress on TNF-alpha-stimulated adhesion molecule expression in human aortic endothelial cells. HAECs, ICAM-1, LSS, VCAM-1
44  2010 [Effects of salvianolic acid B on lipid peroxidation and metalloproteinase-2 activity in fibrotic liver in rat]. Hyp, TBIL
45  2011 Effects of salvianolic Acid B on protein expression in human umbilical vein endothelial cells. HUVECs
46  2011 Investigation of the binding of Salvianolic acid B to human serum albumin and the effect of metal ions on the binding. CD, HSA
47  2011 Modulation of growth and angiogenic potential of oral squamous carcinoma cells in vitro using salvianolic acid B. DMBA, OSCC
48  2011 Salvianolic acid B and tanshinone IIA attenuate myocardial ischemia injury in mice by NO production through multiple pathways. eNOS, HUVECs, NO, Tan IIA
49  2011 Salvianolic acid B inhibits autophagy and protects starving cardiac myocytes. EM
50  2011 Salvianolic acid B inhibits the TLR4-NFkappaB-TNFalpha pathway and attenuates neonatal rat cardiomyocyte injury induced by lipopolysaccharide. HSP70, IOD, LDH, LPS, NF-kappaB, RT-PCR, TLR4, TNF-alpha
51  2011 Salvianolic acid B modulates the expression of drug-metabolizing enzymes in HepG2 cells. GSTs
52  2011 Salvianolic acid B reverses the epithelial-to-mesenchymal transition of HK-2 cells that is induced by transforming growth factor-beta. TGF-beta1
53  2011 Salvianolic acid B suppresses IFN-gamma-induced JAK/STAT1 activation in endothelial cells. SM
54  2011 Salvianolic acid B suppresses maturation of human monocyte-derived dendritic cells by activating PPARgamma. h-monDC, oxLDL
55  2011 Salvianolic Acid B, a potential chemopreventive agent, for head and neck squamous cell cancer. HNSCC
56  2011 Salvianolic acids: small compounds with multiple mechanisms for cardiovascular protection. Sal A
57  2011 Studies on the interaction of salvianolic acid B with human hemoglobin by multi-spectroscopic techniques. HHb
58  2011 Studies on the stability of salvianolic acid B as potential drug material. HPLC, HPLC-TOFMS, NS
59  2011 Therapeutic effects of SMND-309, a new metabolite of salvianolic acid B, on experimental liver fibrosis. CTGF, TGF-beta1
60  2012 Biotransformation of salvianolic acid B by Fusarium oxysporum f. sp. Cucumerinum and its two degradation routes. ---
61  2012 Chemical conversions of salvianolic acid B by decoction in aqueous solution. ---
62  2012 Direct stimulation of adult neural stem/progenitor cells in vitro and neurogenesis in vivo by salvianolic acid B. NSPCs
63  2012 Effects of salvianolic acid B on survival, self-renewal and neuronal differentiation of bone marrow derived neural stem cells. BDNF, BM-NSCs, BrdU
64  2012 Inhibitory effects of salvianolic acid B on apoptosis of Schwann cells and its mechanism induced by intermittent high glucose. IHG, SC, TUNEL
65  2012 Metabolic transformation of DMBA-induced carcinogenesis and inhibitory effect of salvianolic acid b and breviscapine treatment. DMBA, GC-TOF MS, SCC
66  2012 Protective effects of Salvianolic acid B on Schwann cells apoptosis induced by high glucose. 8-OHdG, DPN, HG, SCs
67  2012 Salvianolic Acid B Attenuates Rat Hepatic Fibrosis via Downregulating Angiotensin II Signaling. alpha-SMA, Ang II, AT1R, Col I, HSCs, RAS, TGF-beta
68  2012 Salvianolic acid B exerts vasoprotective effects through the modulation of heme oxygenase-1 and arginase activities. HO-1, iNOS, LPS, NO, SnPP
69  2012 Salvianolic acid B inhibits SDF-1alpha-stimulated cell proliferation and migration of vascular smooth muscle cells by suppressing CXCR4 receptor. SDF-1alpha, VSMCs
70  2012 Salvianolic acid B lowers portal pressure in cirrhotic rats and attenuates contraction of rat hepatic stellate cells by inhibiting RhoA signaling pathway. ET-1, HSCs, MLC2, ROCK
71  2012 Salvianolic acid B prevents bone loss in prednisone-treated rats through stimulation of osteogenesis and bone marrow angiogenesis. GC, MSC
72  2012 The use of PEGylated liposomes to prolong the circulation lifetime of salvianolic acid B. PEG-DSPE 2000
73  2012 [Hydrogen peroxide is involved in the signal transduction of salicylic acid-induced salvianolic acid B biosynthesis in Salvia miltiorrhiza cell cultures]. CAT, IMD, PAL, SA, TAT
74  2012 [Study on protective effect of salvianolic acid B on glutamate-induced excitotoxicity in pheochromocytoma PC12 cells]. ---
75  2013 Anti-inflammatory effects of danshen on human vascular endothelial cells in culture. DS, IL, MCP, TNF
76  2013 Cardioprotective effect of salvianolic acid B against arsenic trioxide-induced injury in cardiac H9c2 cells via the PI3K/Akt signal pathway. ATO
77  2013 Comparison of the inhibitory effect against copper ion-induced oxidation in rat plasma after oral administration of salvianolic acid B and its decocted solutions. CEOOH, DPPH
78  2013 Novel multiple agents loaded PLGA nanoparticles for brain delivery via inner ear administration: in vitro and in vivo evaluation. CSF, I/R, IT, MDA, NOS, NPs, PNS, SOD, TSIIA
79  2013 Quantitative (1)H NMR method for hydrolytic kinetic investigation of salvianolic acid B. DSS, LA, PRO, Sal D, TSP
80  2013 Salvianolic acid B inhibits hepatic stellate cell activation through transforming growth factor beta-1 signal transduction pathway in vivo and in vitro. alpha-SMA, DMN, HSCs, Hyp, TGF
81  2013 The protective effect of salvianolic acid B on blood-spinal cord barrier after compression spinal cord injury in rats. BSCB, HO-1, SCI
82  2013 [Effects of Ca2+ on salicylic-acid induced biosynthesis of salvianolic acid B in young seedlings of Salvia miltiorrhiza Bunge]. SA
83  2014 Cardiomyocyte-like cells differentiation from non beta-catenin expression mesenchymal stem cells. 5-aza, CLM, MSCs
84  2014 Development of Salvianolic acid B-Tanshinone II A-Glycyrrhetinic acid compound liposomes: formulation optimization and its effects on proliferation of hepatic stellate cells. GA, HSC, RP-HPLC, TSN
85  2014 Enhanced local bioavailability of single or compound drugs delivery to the inner ear through application of PLGA nanoparticles via round window administration. NPs, PL, PLGA, PNS, RW, RWM, TSIIA
86  2014 Expression of miR-106b-25 induced by salvianolic acid B inhibits epithelial-to-mesenchymal transition in HK-2 cells. alpha-SMA, EMT, miRNAs, TGF
87  2014 Hydrogen peroxide and nitric oxide are involved in salicylic acid-induced salvianolic acid B production in Salvia miltiorrhiza cell cultures. NO, SA
88  2014 In vivo distribution and pharmacokinetics of multiple active components from Danshen and Sanqi and their combination via inner ear administration. CSF, DAD, IT, PL, TSIIA
89  2014 Mechanism of action of salvianolic acid B by module-based network analysis. CMM, FAG-EC, GO, PIN
90  2014 Pathway engineering for phenolic acid accumulations in Salvia miltiorrhiza by combinational genetic manipulation. AtPAP1, SmCCR
91  2014 Salvianolic acid B inhibited PPARgamma expression and attenuated weight gain in mice with high-fat diet-induced obesity. IPGTT, IPITT, PPARgamma
92  2014 Salvianolic acid B inhibits atherogenesis of vascular cells through induction of Nrf2-dependent heme oxygenase-1. HO-1, Nrf2, PDGF
93  2014 Salvianolic acid B inhibits platelets as a P2Y12 antagonist and PDE inhibitor: evidence from clinic to laboratory. PDE
94  2014 Salvianolic acid B promotes bone formation by increasing activity of alkaline phosphatase in a rat tibia fracture model: a pilot study. ALP, HE
95  2014 Salvianolic acid B promotes osteogenesis of human mesenchymal stem cells through activating ERK signaling pathway. ERK, hMSCs
96  2014 Study on salvianolic acid B in the reduction of epidural fibrosis in laminectomy rats. EF, VEGF
97  2014 The inhibitory effect of salvianolic acid B on TGF-beta1-induced proliferation and differentiation in lung fibroblasts. ECM, ELISA, RT-PCR, TGF-beta1
98  2014 Transformation of salvianolic acid B to salvianolic acid a in aqueous solution and the in vitro liver protective effect of the main products. LA, Sal A
99  2014 [Effects of salvianolic acid B on endothelin-1-induced contraction and cytoskeleton organization of hepatic stellate cells in rats]. ET-1, HSCs, MLC2
100  2015 Antidiabetic potential of salvianolic acid B in multiple low-dose streptozotocin-induced diabetes. MDA, MLDS, OGTT
101  2015 Antioxidant effect of salvianolic acid B on hippocampal CA1 neurons in mice with cerebral ischemia and reperfusion injury. MDA, NIH, NIM, NOS, SOD, T-AOC
102  2015 Differentiation of embryonic stem cells into cardiomyocytes used to investigate the cardioprotective effect of salvianolic acid B through BNIP3 involved pathway. BNIP3, ESCs, HIF-1alpha, MI
103  2015 Effects of salvianolic acid B on liver mitochondria of rats with nonalcoholic steatohepatitis. MDA, Mfn2, NASH, SOD
104  2015 Inhibition of Tanshinone IIA, salvianolic acid A and salvianolic acid B on Areca nut extract-induced oral submucous fibrosis in vitro. ANE, MOMFs, OSF, Sal-A, Tan IIA
105  2015 Inhibitory effect of salvianolate on human cytochrome P450 3A4 in vitro involving a noncompetitive manner. CYP450, HLMs, HPLC
106  2015 Protective effect of salvianolic acid B on NASH rat liver through restoring intestinal mucosal barrier function. AST, DAO, ET, SD, TC, TG
107  2015 Protective Effects and Mechanisms of Salvianolic Acid B Against H₂O₂-Induced Injury in Induced Pluripotent Stem Cell-Derived Neural Stem Cells. iPSCs, MMP, NSCs, pSTAT3, TIMP
108  2015 Salvianolic acid B accelerated ABCA1-dependent cholesterol efflux bytargeting PPAR-gamma and LXRalpha. ABCA1, LXRalpha, PPARgamma
109  2015 Salvianolic acid B attenuates lung inflammation induced by cigarette smoke in mice. BALF, CS, HO-1, i.p, IL-1beta, IL-6, MCP-1, NF-kappaB, Nrf2, TNF-alpha
110  2015 Salvianolic Acid B Down-regulates Matrix Metalloproteinase-9 Activity and Expression in Tumor Necrosis Factor-alpha-induced Human Coronary Artery Endothelial Cells. ERK, HCAECs, MMP-9, NF-kappaB, TNF-alpha
111  2015 Salvianolic acid B improves bone marrow-derived mesenchymal stem cell differentiation into alveolar epithelial cells type I via Wnt signaling. ALI, AQP, ATI, BMSCs, CM, LiCl
112  2015 Salvianolic acid B-induced microRNA-152 inhibits liver fibrosis by attenuating DNMT1-mediated Patched1 methylation. DNMT1, EMT, Hh, HSCs, miRNAs, Ptch1
113  2016 Cardioprotective effect of Salvianolic acid B on acute myocardial infarction by promoting autophagy and neovascularization and inhibiting apoptosis. AMI, HE
114  2016 Combination of chlorogenic acid and salvianolic acid B protects against polychlorinated biphenyls-induced oxidative stress through Nrf2. CADs, CGA, HO-1, Nrf2, SOD
115  2016 Development and validation of a UFLC-MS/MS method for determination of 7'(Z)-(8″S, 8‴S)-epi-salvianolic acid E, (7'R, 8'R, 8″S, 8‴S)-epi-salvianolic acid B and salvianolic acid B in rat plasma and its application to pharmacokinetic studies. ESI, MRM
116  2016 Effects of salvianolic acid B on growth inhibition and apoptosis induction of ovarian cancer SKOV3. ---
117  2016 Effects of ultrasonic processing on degradation of salvianolic acid B in aqueous solution. LC-MS
118  2016 Immobilization of salvianolic acid B-loaded chitosan microspheres distributed three-dimensionally and homogeneously on the porous surface of hydroxyapatite scaffolds. CS, HA
119  2016 MicroRNA-17-5p-activated Wnt/beta-catenin pathway contributes to the progression of liver fibrosis. HSC, MiRNAs, WIF1
120  2016 Mixed Aqueous Extract of Salvia Miltiorrhiza Reduces Blood Pressure through Inhibition of Vascular Remodelling and Oxidative Stress in Spontaneously Hypertensive Rats. AFs, DSS, PAL, ROS, Sal-A, SBP, SHR, SM, SMLP
121  2016 Production of rosmarinic acid and salvianolic acid B from callus culture of Salvia miltiorrhiza with cytotoxicity towards acute lymphoblastic leukemia cells. HPLC-DAD-MS, MS, RA, SM
122  2016 Protection of SAL B with H9C2 cells. ---
123  2016 Salvianolic Acid B (Sal B) Protects Retinal Pigment Epithelial Cells from Oxidative Stress-Induced Cell Death by Activating Glutaredoxin 1 (Grx1). Grx1, Nrf2, RPE, siRNA
125  2016 Salvianolic acid B ameliorates CNS autoimmunity by suppressing Th1 responses. EAE, MS
126  2016 Salvianolic Acid B Ameliorates Hyperglycemia and Dyslipidemia in db/db Mice through the AMPK Pathway. GLUT4, pACC, pAMPK, PPARalpha
127  2016 Salvianolic acid B improves the disruption of high glucose-mediated brain microvascular endothelial cells via the ROS/HIF-1alpha/VEGF and miR-200b/VEGF signaling pathways. HIF-1alpha, miR-200b, RBMECs, ROS, TJ, VEGF
128  2016 Salvianolic acid B improves vascular endothelial function in diabetic rats with blood glucose fluctuations via suppression of endothelial cell apoptosis. eNOS
129  2016 Salvianolic acid B induced upregulation of miR-30a protects cardiac myocytes from ischemia/reperfusion injury. IR, LDH, miRNAs
130  2016 Salvianolic acid B protects against doxorubicin induced cardiac dysfunction via inhibition of ER stress mediated cardiomyocyte apoptosis. DOX
131  2016 Salvianolic acid B reduced the formation of epidural fibrosis in an experimental rat model. EF, VEGF
132  2016 Salvianolic Acid B Restored Impaired Barrier Function via Downregulation of MLCK by microRNA-1 in Rat Colitis Model. miR-1, TNBS
133  2016 Salvianolic acid B stimulates osteogenesis in dexamethasone-treated zebrafish larvae. ALP, DEX, IOD, OC
134  2016 Salvianolic acid B, a novel autophagy inducer, exerts antitumor activity as a single agent in colorectal cancer cells. ---
135  2016 Simultaneous determination of tanshinones and polyphenolics in rat plasma by UPLC-MS/MS and its application to the pharmacokinetic interaction between them. CT, DSS, ESI, LLE, MRM, PAL, RA, SMB, T-I, TSIIA
136  2016 [Effects of salvianolic acid B on osteogenic differentiation of human periodontal ligament cells]. ALP, hPDLCs, MTT, OCN
137  2016 [The effect of Salvianolic Acid B on the Apoptosis of HUVECs Induced by Intermittent High Glucose]. HUVECs, MDA, NO, T-AOC
138  2017 alphavbeta3 integrin receptor specific peptide modified, salvianolic acid B and panax notoginsenoside loaded nanomedicine for the combination therapy of acute myocardial ischemia. LPNs, PNS
139  2017 BMP-2 combined with salvianolic acid B promotes cardiomyocyte differentiation of rat bone marrow mesenchymal stem cells. BMP-2, BMSCs
140  2017 Calcium homeostasis and endoplasmic reticulum stress are involved in Salvianolic acid B-offered protection against cardiac toxicity of arsenic trioxide. ATO, ERS
141  2017 Coordination-driven assembly of catechol-modified chitosan for the kidney-specific delivery of salvianolic acid B to treat renal fibrosis. ECM, EMT, HChi-Ca-Sal B, UUO
142  2017 Decrease in the Generation of Amyloid-beta Due to Salvianolic Acid B by Modulating BACE1 Activity. AD, FL-APP, SwedAPP
143  2017 Effects of salvianolic acid B on L-type calcium channels and myocardial contractility in isolated rat ventricular myocytes and hERG K+ channels expressed in HEK293 cells. LQTS
144  2017 Function Analysis of Caffeoyl-CoA O-Methyltransferase for Biosynthesis of Lignin and Phenolic Acid in Salvia miltiorrhiza. MeJA
145  2017 LincRNA-p21 Inhibits the Wnt/beta-Catenin Pathway in Activated Hepatic Stellate Cells via Sponging MicroRNA-17-5p. alpha-SMA, HSCs, lincRNA-p21, lncRNAs, miRNAs
146  2017 Overexpression of SmMYC2 Increases the Production of Phenolic Acids in Salvia miltiorrhiza. ---
147  2017 Regulation of SIRT3/FOXO1 Signaling Pathway in Rats with Non-alcoholic Steatohepatitis by Salvianolic Acid B. IP, NASH, ROS, SD
148  2017 Salvianolic acid B and danshensu induce osteogenic differentiation of rat bone marrow stromal stem cells by upregulating the nitric oxide pathway. ALP, DSU, MSCs, NO, OCN, OPG, RANKL
149  2017 Salvianolic acid B attenuates doxorubicin-induced ER stress by inhibiting TRPC3 and TRPC6 mediated Ca2+ overload in rat cardiomyocytes. DOX, ER, TRPC
150  2017 Salvianolic acid B attenuates oxidized low-density lipoprotein-induced endothelial cell apoptosis through inhibition of oxidative stress, p53, and caspase-3 pathways. HUVECs, MDA, oxLDL, SOD
151  2017 Salvianolic Acid B Inhibits High-Fat Diet-Induced Inflammation by Activating the Nrf2 Pathway. COX-2, HF, HFD, iNOS, NF-kappaB, Nrf2
152  2017 Salvianolic acid B inhibits IL-1beta-induced inflammatory cytokine production in human osteoarthritis chondrocytes and has a protective effect in a mouse osteoarthritis model. OA
153  2017 Salvianolic acid B inhibits intermittent high glucose-induced INS-1 cell apoptosis through regulation of Bcl-2 proteins and mitochondrial membrane potential. MDA, MMP, PARP
154  2017 Salvianolic acid B prevents steroid-induced osteonecrosis of the femoral head via PPARgamma expression in rats. PPAR
155  2017 Salvianolic acid B protects hepatocytes from H2O2 injury by stabilizing the lysosomal membrane. Cat, LAMP1, MDA, PCC
156  2017 Salvianolic acid B regulates gene expression and promotes cell viability in chondrocytes. ---
157  2017 Simultaneous determination and pharmacokinetic study of four phenolic acids in rat plasma using UFLC-MS/MS after intravenous administration of salvianolic acid for injection. ESI, LA, MRM, PP, RA, SAFI, Sal D
158  2017 Synthesis and study the properties of StNPs/gum nanoparticles for salvianolic acid B-oral delivery system. StNPs
159  2017 The Protein Kinase SmSnRK2.6 Positively Regulates Phenolic Acid Biosynthesis in Salvia miltiorrhiza by Interacting with SmAREB1. ABRE, RA, SnRK2
160  2017 Treatment with salvianolic acid B restores endothelial function in angiotensin II-induced hypertensive mice. Ang II, DHE, HUVECs, ROS
161  2017 [Preparation and in vivo study of liposomes mediated by glycyrrhetinic acid derivative ligand 18-GA-Gly]. ---
162  2018 Antitumor properties of Salvianolic acid B against triple-negative and hormone receptor-positive breast cancer cells via ceramide-mediated apoptosis. TNBC
163  2018 Mechanism of salvianolic acid B neuroprotection against ischemia/reperfusion induced cerebral injury. MRI, qRT-PCR, TTC
164  2018 Polypharmacological Profiles Underlying the Antitumor Property of Salvia miltiorrhiza Root (Danshen) Interfering with NOX-Dependent Neutrophil Extracellular Traps. citH3, DHTI, MPO, NE, NETs, NOX
165  2018 Salvianolic acid B as an anti-emphysema agent I: In vitro stimulation of lung cell proliferation and migration, and protection against lung cell death, and in vivo lung STAT3 activation and VEGF elevation. HMVEC-L, JAK2, STAT3, VEGF
166  2018 Salvianolic acid B as an anti-emphysema agent II: In vivo reversal activities in two rat models of emphysema. CSE, MDA, MLI, MMP, MPO, PCNA, PPE, pSTAT3, STAT3, VEGF
167  2018 Salvianolic Acid B Enhances Hepatic Differentiation of Human Embryonic Stem Cells Through Upregulation of WNT Pathway and Inhibition of Notch Pathway. ESCs, HES, LEF, TCF
168  2018 Salvianolic acid B inhibits Ang II-induced VSMC proliferation in vitro and intimal hyperplasia in vivo by downregulating miR-146a expression. VSMC
169  2018 Salvianolic acid B inhibits glycolysis in oral squamous cell carcinoma via targeting PI3K/AKT/HIF-1alpha signaling pathway. HIF-1alpha, MMP, NGS, OSCC, PI3K
170  2018 Salvianolic acid B promotes neural differentiation of induced pluripotent stem cells via PI3K/AKT/GSK3beta/beta-catenin pathway. iPSCs, NSCs, PI3K
171  2018 Salvianolic Acid B Promotes the Survival of Random-Pattern Skin Flaps in Rats by Inducing Autophagy. ---
172  2018 SmbHLH37 Functions Antagonistically With SmMYC2 in Regulating Jasmonate-Mediated Biosynthesis of Phenolic Acids in Salvia miltiorrhiza. bHLH, JAs, JAZ, TF
173  2018 SmMYB111 Is a Key Factor to Phenolic Acid Biosynthesis and Interacts with Both SmTTG1 and SmbHLH51 in Salvia miltiorrhiza. bHLH, MYB, TTG1
174  2018 Synergistic Effects of Salvianolic Acid B and Puerarin on Cerebral Ischemia Reperfusion Injury. IS, Pue
175  2018 TGF-beta1 combined with Sal-B promotes cardiomyocyte differentiation of rat mesenchymal stem cells. BMSCs, CMs, cTnI, GATA4, TGF-beta1
176  2019 Pharmacokinetics of Salvianolic acid B, Rosmarinic acid and Danshensu in rat after pulmonary administration of Salvia miltiorrhiza polyphenolic acid solution. DA, Ros A, SMPA
177  2019 Sal B targets TAZ to facilitate osteogenesis and reduce adipogenesis through MEK-ERK pathway. TAZ
178  2019 Salvianolic acid B ameliorates liver injury in a murine aGvHD model by decreasing inflammatory responses via upregulation of HO-1. aGVHD
179  2019 Salvianolic acid B plays an anti-obesity role in high fat diet-induced obese mice by regulating the expression of mRNA, circRNA, and lncRNA. circRNA, lncRNA, WAT
180  2019 Salvianolic acid B remits LPS-induced injury by up-regulating miR-142-3p in MH7A cells. LPS, RA