3650816 WFS1 Wolfram syndrome 1 45 3650815 WFS1 Wolfram syndrome 1 gene 20 3650811 WFS1 WFS type 1 2 3650809 WFS1 WFS1 gene, encoding wolframin 2 3650813 WFS1 WS was identified in 4p16.1 2 3650812 WFS1 WFS patients show type 1 syndrome 1 3650810 WFS1 WFS1 gene 1 3650814 WFS1 WFS1, leading to p.H696Y substitution at the C-terminus of Wolframin 1