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■ Search Result - Abbreviation : 8-OH-DPAT

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Abbreviation: 8-OH-DPAT
Appearance Frequency: 582 time(s)
Long forms: 29

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Long Form No. Long Form Research Area Co-occurring Abbreviation PubMed/MEDLINE Info. (Year, Title)
agonist 8-hydroxy-2-(di-n-propylamino)tetralin
(544 times)
Pharmacology
(276 times)
5-HT (88 times)
DOI (46 times)
5-HT1A (20 times)
1984 Evidence that 5-HT agonist-induced rotational behaviour in the rat is mediated via 5-HT1 receptors.
8-OH-2-(di-n-propylamino)tetralin
(9 times)
Pharmacology
(5 times)
5-CT (1 time)
DOB (1 time)
DOM (1 time)
1984 The binding of serotonergic ligands to the porcine choroid plexus: characterization of a new type of serotonin recognition site.
microgram/microliter 8-hydroxy-2-(di-n-propylamino)tetralin
(2 times)
Pharmacology
(1 time)
--- 1993 Stimulation of hippocampal 5-HT1A receptors causes amnesia and anxiolytic-like but not antidepressant-like effects in the rat.
oxytocin responses to the 5-HT1A receptor agonists 8-hydroxy-2-(di-n-propylamino) tetralin
(2 times)
Psychiatry
(1 time)
ACTH (1 time)
DOI (1 time)
DRM (1 time)
1993 Stimulation of 5-HT1A and 5-HT2/5-HT1C receptors induce oxytocin release in the male rat.
(3-(1,2,5,6-tetrahydropyrid-4-yl)pyrrolo(3,2-b)pyrid-5-one), and the 5-HT1A receptor selective agonist 8-hydroxy-2-(di-n-propylamino)-tetralin
(1 time)
Pharmacology
(1 time)
--- 1998 The effects of 5-HT1A, 5-HT1B and 5-HT1D receptor agonists on trigeminal nociceptive neurotransmission in anaesthetized rats.
1-day-old rats with the putative selective agonists 8-hydroxy-2-(di-n-propylamino)tetralin
(1 time)
Psychopharmacology
(1 time)
--- 1992 Serotonin receptor ontogeny: effects of agonists in 1-day-old rats.
2-methyl-5-hydroxytryptamine, 8-hydroxy-2-(di-N-propylamino) tetralin hydrobromide
(1 time)
Pharmacology
(1 time)
5-CT (1 time)
5-HT (1 time)
5-MeOT (1 time)
1988 Responses to 5-hydroxytryptamine evoked in the hemisected spinal cord of the neonate rat.
agonist 8-hydroxy-DPAT hydroxybromide
(1 time)
Neurology
(1 time)
5-HT1A (1 time)
RFs (1 time)
WDR (1 time)
2001 The role of 5-hydroxytryptamine1A and 5-hydroxytryptamine1B receptors in modulating spinal nociceptive transmission in normal and carrageenan-injected rats.
hippocampal 5-HT1A density as measured by ((3)H) 8-hydroxy-2-(di-n-propylamino) tetralin
(1 time)
Endocrinology
(1 time)
BTBR (1 time)
CORT (1 time)
HPA (1 time)
2014 Enhanced novelty-induced corticosterone spike and upregulated serotonin 5-HT1A and cannabinoid CB1 receptors in adolescent BTBR mice.
10  observed with 5-HT1A receptor agonists: N,N-dipropyl-8-hydroxy-2-aminotetralin
(1 time)
Biochemistry
(1 time)
d-LSD (1 time)
DOM (1 time)
1993 Activity of serotonin (5-HT) receptor agonists, partial agonists and antagonists at cloned human 5-HT1A receptors that are negatively coupled to adenylate cyclase in permanently transfected HeLa cells.
11  observed with the 5-HT1A agonist R (+)-2-dipropylamino-8-hydroxy-1,2,3, 4-tetrahydronaphthalene hydrobromide
(1 time)
Chemistry
(1 time)
--- 1999 Regulation of glial Na+/K+-ATPase by serotonin: identification of participating receptors.
12  observed with the prototypical serotonin 1A agonist (+/-)-8-hydroxy-2-(DI-n-propyl-amino)tetralin hydrobromide
(1 time)
Neurology
(1 time)
--- 2003 Serotonergic serotonin (1A) mixed agonists/antagonists elicit large-magnitude phase shifts in hamster circadian wheel-running rhythms.
13  obtained were compared with those induced by treatment with 8-hydroxy-2(di-n-propyl-amino)tetralin
(1 time)
Pharmacology
(1 time)
--- 1994 Effects of FG 5893, a new compound with 5-HT1A receptor agonistic and 5-HT2 receptor antagonistic properties, on male rat sexual behavior.
14  obtained with 30 nM 5-HT, while 8-hydroxy-2-(di-n-propylamino)-tetralin
(1 time)
Brain
(1 time)
--- 1990 Serotonin receptors expressed in Xenopus oocytes by mRNA from brain mediate a closing of K+ membrane channels.
15  oil and the 5-HT1A receptor agonist 8-hydroxy-2-(di-n-propylamino)tetralin
(1 time)
Pharmacology
(1 time)
--- 2013 Anxiolytic-like effect of lavender essential oil inhalation in mice: participation of serotonergic but not GABAA/benzodiazepine neurotransmission.
16  Only treatment with the 5-HT1A receptor agonist 8-hydroxy-dipropylaminotetralin
(1 time)
Neurology
(1 time)
NRG-1 (1 time)
PPI (1 time)
2009 Neuregulin 1 hypomorphic mutant mice: enhanced baseline locomotor activity but normal psychotropic drug-induced hyperlocomotion and prepulse inhibition regulation.
17  orexigenic compound, namely the 5-HT1A receptor agonist 8-hydroxy-2-(di-n-propylamino)tetralin
(1 time)
Psychopharmacology
(1 time)
d-FEN (1 time)
1989 Dextrofenfluramine, but not 8-OH-DPAT affects the decrease in food consumed by rats submitted to physical exercise.
18  other 5-HT1A agonists such as 8-hydroxy-2-(di-n-propylamino) tetralin
(1 time)
Psychopharmacology
(1 time)
DA (1 time)
PCPA (1 time)
1987 Blockade of dopamine receptors explains the lack of 5-HT stereotypy on treatment with the putative 5-HT1A agonist LY165163.
19  other anxiolytic agents: the 5-HT1A agonists, buspirone and 8-hydroxy-2-(di-n-propylamino)-tetralin HBr
(1 time)
Psychopharmacology
(1 time)
SI (1 time)
2000 The selective serotonin (5-HT)1A receptor ligand, S15535, displays anxiolytic-like effects in the social interaction and Vogel models and suppresses dialysate levels of 5-HT in the dorsal hippocampus of freely-moving rats. A comparison with other anxiolytic agents.
20  other hand, 8hydroxy-dipropylaminotetralin
(1 time)
Drug Therapy
(1 time)
5-CT (1 time)
mCPBG (1 time)
NE (1 time)
2002 Pharmacology of serotonin receptors modulating electrically-induced [3h]-norepinephrine release from isolated mammalian iris-ciliary bodies.
21  other serotonergic agents, such as ketanserin, 8-hydroxy-2-(di-n-propylamino)tetralin
(1 time)
Physiology
(1 time)
AChRs (1 time)
1999 Blockage of mouse muscle nicotinic receptors by serotonergic compounds.
22  out whether (+/-)-8-hydroxy-2(di-n-propylamino)tetralin
(1 time)
Neurology
(1 time)
EMG (1 time)
2003 Contribution of the serotonin 5-HT1A receptor agonism of 8-OH-DPAT and EMD 128130 to the regulation of haloperidol-induced muscle rigidity in rats.
23  ovariectomized animals received 8-hydroxy-2-(di-N-propylamino)tetralin
(1 time)
Neurology
(1 time)
--- 2014 Serotonergic 5-HT2A/2C receptors are involved in prolactin secretion in hyperestrogenic rats.
24  over the (-) isomer. d-Amphetamine, phencyclidine, 8-hydroxy-2-(di-n-propylamino)tetralin
(1 time)
Psychopharmacology
(1 time)
DS (1 time)
1989 Studies on the discriminative stimulus properties of apomorphine in rhesus monkeys.
25  over the 8-h recording period after the 5-HT(1A) agonist 8-hydroxy-2-(di-n-propylamino)tetralin
(1 time)
Brain
(1 time)
i.t (1 time)
TSWS (1 time)
1996 Sleep/waking effects following intrathecal administration of the 5-HT(1A) Agonist 8-OH-DPAT alone and in combination with the putative 5-HT(1A) antagonist NAN-190 in rats.
26  oxide synthase(NOS) inhibitors on 8-hydroxy-2-di-n-(propylamino)tetralin
(1 time)
Biology
(1 time)
7-NI (1 time)
L-NAME (1 time)
nNOS (1 time)
1999 Involvement of nitric oxide in the 5-HT1A autoreceptor-mediated hyperphagia in rats.
27  oxytocin and ACTH responses to the 5-HT(1A) agonist 8-hydroxy-dipropylamino-tetralin
(1 time)
Neurology
(1 time)
--- 2000 Evidence that G(z)-proteins couple to hypothalamic 5-HT(1A) receptors in vivo.
28  receptor, 8-hydroxy-DPAT
(1 time)
Neurology
(1 time)
EGF (1 time)
1997 Role of the 5-HT1A receptor in development of the neonatal rat brain: preliminary behavioral studies.
29  transduction. ((3)H)8-Hydroxy-2-dipropylaminotetralin
(1 time)
Drug Therapy
(1 time)
5-HT (1 time)
RASSL (1 time)
2009 Mutant 5-hydroxytryptamine 1A receptor D116A is a receptor activated solely by synthetic ligands with a rich pharmacology.