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Abbreviation: ACNU
Appearance Frequency: 201 time(s)
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Long Form No. Long Form Research Area Co-occurring Abbreviation PubMed/MEDLINE Info. (Year, Title)
1-(4-amino-2-methyl-5-pyrimidinyl)methyl-3-(2-chloroethyl)-3-nitrosourea hydrochloride
(168 times)
Neoplasms
(93 times)
MGMT (21 times)
CENUs (11 times)
5-FU (6 times)
1975 Effect of 3-[4-amino-2-methyl-5-pyrimidinyl)ethyl[-1(2-chloroethyl)-1-nitrosourea hydrochloride on lymphoid leukemia L-1210.
agents: nimustine hydrochloride
(3 times)
Neoplasms
(3 times)
5-FU (2 times)
ADM (2 times)
MMC (2 times)
1983 In vitro studies on potentiation of cytotoxic effects of anticancer drugs by interferon on a human neoplastic cell line (HeLa).
anticancer drug nimustine
(2 times)
Biophysics
(1 time)
5-FU (1 time)
ADM (1 time)
AP-1 (1 time)
1985 [Effects of anticancer drugs on multicellular spheroid of 9L rat brain tumor].
accelerator was given in conjunction with chemotherapy of nimustine hydrochloride
(1 time)
Brain
(1 time)
ED (1 time)
FDG (1 time)
NSD (1 time)
1989 [Radiochemotherapy-related changes in the brain parenchyma of glioma patients evaluated repeatedly by C15O2, C15O, 15O2, and 18F-fluorodeoxyglucose (FDG) PET].
accumulation in the normal brain, whereas nimustine
(1 time)
Brain
(1 time)
5-FU (1 time)
1993 Uptake of drugs and expression of P-glycoprotein in the rat 9L glioma.
acid pellets containing nimustine chloride
(1 time)
Neurosurgery
(1 time)
GB (1 time)
1994 Interstitial chemotherapy with biodegradable ACNU pellet for glioblastoma.
ACNU, a small pellet
(1 time)
Neurosurgery
(1 time)
GB (1 time)
1994 Interstitial chemotherapy with biodegradable ACNU pellet for glioblastoma.
active comparator, new user
(1 time)
Drug Therapy
(1 time)
CI (1 time)
GERD (1 time)
H2RA (1 time)
2019 Extreme restriction design as a method for reducing confounding by indication in pharmacoepidemiologic research.
activity order of three kinds of drugs is Nimustine
(1 time)
Molecular Biology
(1 time)
RLS (1 time)
2017 The efficacy assessments of alkylating drugs induced by nano-Fe3O4/CA for curing breast and hepatic cancer.
10  addition, the immunosuppressive effect of a water-soluble nitrosourea derivative
(1 time)
Antineoplastic Agents
(1 time)
rIL-2 (2 times)
LAK (1 time)
1986 [Strategy of cancer treatment using human recombinant interleukin 2 and lymphokine activated killer cells].
11  adjuvant chemotherapy consisting of temozolomide or nimustine
(1 time)
Neoplasms
(1 time)
HUVEC (1 time)
2013 Human umbilical vein endothelial cell vaccine therapy in patients with recurrent glioblastoma.
12  adjuvant chemotherapy with nimustine
(1 time)
Antineoplastic Agents
(1 time)
AA (1 time)
GBM (1 time)
MGMT (1 time)
2013 Randomized trial of chemoradiotherapy and adjuvant chemotherapy with nimustine (ACNU) versus nimustine plus procarbazine for newly diagnosed anaplastic astrocytoma and glioblastoma (JCOG0305).
13  adjuvant local delivery of nimustine
(1 time)
Neoplasms
(1 time)
GBM (1 time)
KPS (1 time)
OS (1 time)
2018 Enhanced antitumor effects of radiotherapy combined local nimustine delivery rendezvousing with oral temozolomide chemotherapy in glioblastoma patients.
14  administered CSF perfusion chemotherapy with nimustine
(1 time)
Drug Therapy
(1 time)
CSF (1 time)
MTX (1 time)
1998 Pharmacokinetics of nimustine, methotrexate, and cytosine arabinoside during cerebrospinal fluid perfusion chemotherapy in patients with disseminated brain tumors.
15  administrations of nimustine hydrochloride
(1 time)
Neoplasms
(1 time)
ECOG (1 time)
PS (1 time)
SCLC (1 time)
2009 Phase II study of nimustine hydrochloride (ACNU) plus paclitaxel for refractory small cell lung cancer.
16  adriamycin (ADM) with nimustine hydrochloride
(1 time)
Gastroenterology
(1 time)
5-FU (1 time)
ADM (1 time)
CR (1 time)
1997 Multicenter randomized study on Me-CCNU, 5-FU and ADM vs ACNU, 5-FU and ADM for treatment of advanced gastric cancer.
17  adriamycin, cisplatin, nimustine
(1 time)
Antineoplastic Agents
(1 time)
CR (1 time)
EACAM (1 time)
PR (1 time)
1985 [Combination chemotherapy with cyclophosphamide, adriamycin, cisplatin, nimustine(ACNU), and methotrexate (EACAM) in advanced adenocarcinoma of the lung].
18  alphaMRP1-Rz cells were significantly sensitive to nitrosourea
(1 time)
Neoplasms
(1 time)
DOX (1 time)
MRP1 (1 time)
2003 Reversal of drug resistance mediated by hammerhead ribozyme against multidrug resistance-associated protein 1 in a human glioma cell line.
19  amino methyl pyrimidinyl methyl chlorethyl nitrorosourea hydrochloride
(1 time)
Otolaryngology
(1 time)
VCR (1 time)
1996 [Case reports of mucosal melanoma of the head and neck].
20  Amino-Methyl-Pyrimidinyl-Methyl-Chlorethyl-Nitrosourea-Hydrochlori de
(1 time)
General Surgery
(1 time)
DTIC (1 time)
VCR (1 time)
1992 Primary anorectal malignant melanoma.
21  anti-cancer drug
(1 time)
Medicine
(1 time)
LLLT (1 time)
Mu-beta-IFN (1 time)
1993 Role of 830 nm low reactive level laser on the growth of an implanted glioma in mice.
22  anti-tumor efficacy of nimustine hydrochloride
(1 time)
Neurology
(1 time)
CED (1 time)
2012 Safety and feasibility of convection-enhanced delivery of nimustine hydrochloride co-infused with free gadolinium for real-time monitoring in the primate brain.
23  antitumor drug, nimustine hydrochloride
(1 time)
Neurology
(1 time)
bp (1 time)
1988 In vitro damage of isolated DNA from two brain tumor cell lines induced by a water-soluble antitumor nitrosourea.
24  Arbor Clinical Nutrition Updates
(1 time)
Nutritional Sciences
(1 time)
--- 2005 Arbor Clinical Nutrition Updates: evidence-based clinical nutrition education using the Internet.
25  arising from nimustine hydrochloride
(1 time)
Medical Oncology
(1 time)
NwSVM (1 time)
SVM (1 time)
2018 Machine-Learning Approach for Modeling Myelosuppression Attributed to Nimustine Hydrochloride.
26  assessment disclosed that cyclophosphamide, cis-platinum, nitrosourea
(1 time)
Neoplasms
(1 time)
HSR (1 time)
1986 Effects of cyclophosphamide, cis-platinum, nitrosourea (ACNU), melphalan, and dacarbazine on a cytogenetically highly malignant neuroblastoma xenograft.
27  authors investigated in vitro cytotoxic effects of nimustine hydrochloride
(1 time)
Neoplasms
(1 time)
AUC (1 time)
MMC (1 time)
SCLC (1 time)
1992 In vitro measurement of chemosensitivity of human small cell lung and gastric cancer cell lines toward cell cycle phase-nonspecific agents under the clinically equivalent area under the curve.
28  cyclophosphamide and nimustine hydrochloride
(1 time)
Neoplasms
(1 time)
--- 1996 Successful treatment with ranimustine and carboplatin for recurrent intraocular retinoblastoma with vitreous seeding.
29  cyclophosphamide, cis-platinum, nitrosourea
(1 time)
Neoplasms
(1 time)
HSR (1 time)
1986 Effects of cyclophosphamide, cis-platinum, nitrosourea (ACNU), melphalan, and dacarbazine on a cytogenetically highly malignant neuroblastoma xenograft.
30  cyto- and genotoxicity of nimustine
(1 time)
Cell Biology
(1 time)
CNUs (1 time)
DSB (1 time)
HR (1 time)
2012 Chloroethylnitrosourea-induced cell death and genotoxicity: cell cycle dependence and the role of DNA double-strand breaks, HR and NHEJ.
31  multi-agent chemotherapy, including procarbazine, nimustine
(1 time)
Neoplasms
(1 time)
--- 2006 Hyperfractionated radiotherapy and multi-agent chemotherapy (procarbazine, ACNU and vincristine) for high-grade gliomas: a prospective study.