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Abbreviation: AICAR
Appearance Frequency: 891 time(s)
Long forms: 30

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Long Form No. Long Form Research Area Co-occurring Abbreviation PubMed/MEDLINE Info. (Year, Title)
5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside
(812 times)
Biochemistry
(175 times)
AMPK (538 times)
ACC (32 times)
AMP (31 times)
1966 Aminoimidazolecarboxamide ribotide (AICAR)-transformylase of erythrocytes in formiminotransferase deficiency syndrome.
5-amino-1-beta-D-ribofuranosyl-imidazole-4-carboxamide
(16 times)
Physiology
(2 times)
AMPK (12 times)
AMP (3 times)
WT (3 times)
1999 Mechanism-based design of inosine 5-monophosphate dehydrogenase inhibitors: synthesis and biological activities of 5-ethynyl-1-beta-D-ribofuranosylimidazole-4-carboxamide (EICAR) and its derivatives.
activator
(15 times)
Physiology
(3 times)
AMPK (10 times)
AD (1 time)
Ad-shNR1 (1 time)
2009 Metformin prevents progression of heart failure in dogs: role of AMP-activated protein kinase.
5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate
(10 times)
Biochemistry
(5 times)
AMPK (4 times)
5'-ProFAR (1 time)
AA (1 time)
1993 Imidazole glycerol phosphate synthase: the glutamine amidotransferase in histidine biosynthesis.
AICA-riboside
(5 times)
Molecular Biology
(1 time)
AMPK (4 times)
ACC (1 time)
ACh (1 time)
1989 Utility of AICAr for metabolic studies is diminished by systemic effects in situ.
5-amino-4-imidazole carboxamide ribonucleotide 5'-phosphate
(4 times)
Biochemistry
(3 times)
6-MP (2 times)
MTX (2 times)
PRPP (2 times)
1986 Sequence-, time- and dose-dependent synergism of methotrexate and 6-mercaptopurine in malignant human T-lymphoblasts.
N1-(b-D-ribofuranosyl)-5-aminoimidazole-4-carboxamide
(4 times)
Biophysics
(1 time)
AMPK (4 times)
ER (2 times)
BiP (1 time)
2011 Glucosensing by GnRH neurons: inhibition by androgens and involvement of AMP-activated protein kinase.
5'-phosphoribosyl-5-aminoimidazole-4-carboxamide
(2 times)
Pediatrics
(1 time)
10-formyl-H2folate (1 time)
10-formyl-H4folate (1 time)
AICA (1 time)
1977 Lesch-Nyhan syndrome: the synthesis of inosine 5'-phosphate in the hypoxanthine-guanine phosphoribosyltransferase-deficient erythrocyte by alternate biochemical pathways.
AICA ribonucleotide
(2 times)
Cell Biology
(1 time)
ES cells (2 times)
AMPK (1 time)
DAVID (1 time)
2013 AICAR sustains J1 mouse embryonic stem cell self-renewal and pluripotency by regulating transcription factor and epigenetic modulator expression.
10  5'-Phosphoribosyl-4-carboxamide-5-aminoimidazole
(1 time)
Genetics
(1 time)
--- 2005 Revisiting purine-histidine cross-pathway regulation in Saccharomyces cerevisiae: a central role for a small molecule.
11  5-amino-4-carboxamide imidazole riboside 5'-phosphate
(1 time)
Genetics
(1 time)
--- 1993 The pleiotropic effects of his overexpression in Salmonella typhimurium do not involve AICAR-induced mutagenesis.
12  5-Aminoimidazole-4-carboxamide riboside or acadesine
(1 time)
Hematology
(1 time)
AMPK (1 time)
ATM (1 time)
CLL (1 time)
2010 AICAR induces apoptosis independently of AMPK and p53 through up-regulation of the BH3-only proteins BIM and NOXA in chronic lymphocytic leukemia cells.
13  acid insoluble carnitine
(1 time)
Biochemistry
(1 time)
ASCAR (1 time)
TCAR (1 time)
1999 Total acid soluble and insoluble carnitine levels in human brain tumors.
14  activator of AMPK
(1 time)
Complementary Therapies
(1 time)
HUVECs (1 time)
2019 Luteolin: A Natural Flavonoid Enhances the Survival of HUVECs against Oxidative Stress by Modulating AMPK/PKC Pathway.
15  activator ZMP
(1 time)
Chemistry Techniques, Analytical
(1 time)
AMPK (1 time)
CBS (1 time)
2007 Structure of a CBS-domain pair from the regulatory gamma1 subunit of human AMPK in complex with AMP and ZMP.
16  active monophosphate form
(1 time)
Biochemistry
(1 time)
AICAr (1 time)
2014 Identification of yeast and human 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranoside (AICAr) transporters.
17  activity of phosphoribosylaminoimidazolecarboxamide
(1 time)
Science
(1 time)
MTX (1 time)
1985 Inhibition of phosphoribosylaminoimidazolecarboxamide transformylase by methotrexate and dihydrofolic acid polyglutamates.
18  adenine nucleotide precursor supplementation
(1 time)
Vascular Diseases
(1 time)
--- 1986 Biochemical studies: failure of tissue adenosine triphosphate levels to predict recovery of contractile function after controlled reperfusion.
19  adipocytes was supplemented with 100 muM ((2R,3S,4R,5R)-5-(4-Carbamoyl-5-aminoimidazol-1-yl)-3,4-dihydroxyoxolan-2-yl)methyl dihydrogen phosphate
(1 time)
Medicine
(1 time)
AMPK (2 times)
hADMSCs (1 time)
2016 AMP-Activated Kinase (AMPK) Activation by AICAR in Human White Adipocytes Derived from Pericardial White Adipose Tissue Stem Cells Induces a Partial Beige-Like Phenotype.
20  agonist, 5 -aminoimidazole -4 -carboxamide -1-beta-d-ribofuranoside
(1 time)
Biochemistry
(1 time)
AMPK (1 time)
ECs (1 time)
EIMD (1 time)
2015 Activation of AMP-activated protein kinase induce expression of FoxO1, FoxO3a, and myostatin after exercise-induced muscle damage.
21  AICA riboside, acadesine
(1 time)
Pharmacology
(1 time)
NMDA (1 time)
1996 Potentiation of excitatory amino acid-evoked adenosine release from rat cortex by inhibitors of adenosine kinase and adenosine deaminase and by acadesine.
22  AICA-ribose
(1 time)
Biochemistry
(1 time)
AMPK (1 time)
FLCN (1 time)
MNU (1 time)
2012 Activation of AMP-activated protein kinase by MAPO1 and FLCN induces apoptosis triggered by alkylated base mismatch in DNA.
23  AICAR injections
(1 time)
Physiology
(1 time)
AMPK (1 time)
beta-HAD (1 time)
FFAs (1 time)
2010 Chronic AMP-activated protein kinase activation and a high-fat diet have an additive effect on mitochondria in rat skeletal muscle.
24  AICAR monophosphate
(1 time)
Biochemistry
(1 time)
AMPK (1 time)
2010 Ethanol inhibits gastric acid secretion in rats through increased AMP-kinase activity.
25  AMP-activated protein kinase
(1 time)
Biology
(1 time)
CPI-17 (1 time)
MLCK (1 time)
MLCP (1 time)
2014 Vascular O-GlcNAcylation augments reactivity to constrictor stimuli by prolonging phosphorylated levels of the myosin light chain.
26  AMPK in controlling aminoimidazole-4-carboxymide-1-beta-d-ribofuranoside
(1 time)
Physiology
(1 time)
ACC2 (1 time)
AMPK (1 time)
KD (1 time)
2008 AMPK-independent pathways regulate skeletal muscle fatty acid oxidation.
27  AMPK inhibitor, Compound C. AMPK activator
(1 time)
ACC (1 time)
ACS (1 time)
AMPK (1 time)
2010 Mechanical Stretch-Induced Protection against Myocardial Ischemia-Reperfusion Injury Involves AMP-Activated Protein Kinase.
28  AMPK specific activator
(1 time)
Cell Biology
(1 time)
AMPK (1 time)
MAPK (1 time)
PKB (1 time)
2013 Adiponectin inhibits neutrophil apoptosis via activation of AMP kinase, PKB and ERK 1/2 MAP kinase.
29  biosynthesis-5-amino-4-imidazolecarboxamide ribotide
(1 time)
Biomedical Engineering
(1 time)
AICA (1 time)
AICAr (1 time)
IMP (1 time)
2006 Diagnosing AICA-ribosiduria by capillary electrophoresis.
30  p-ribosyl-s-amino-imidazole carboxamide
(1 time)
Biochemistry
(1 time)
FAS (1 time)
2006 Cerulenin-mediated apoptosis is involved in adenine metabolic pathway.