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Abbreviation: ATIC
Appearance Frequency: 37 time(s)
Long forms: 11

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Long Form No. Long Form Research Area Co-occurring Abbreviation PubMed/MEDLINE Info. (Year, Title)
5-aminoimidazole-4-carboxamide ribonucleotide transformylase
(9 times)
Rheumatology
(5 times)
MTX (6 times)
TS (3 times)
FPGS (2 times)
2004 Polyglutamation of methotrexate with common polymorphisms in reduced folate carrier, aminoimidazole carboxamide ribonucleotide transformylase, and thymidylate synthase are associated with methotrexate effects in rheumatoid arthritis.
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
(7 times)
Molecular Biology
(2 times)
ALCL (2 times)
ALK (2 times)
CLTC (2 times)
2000 Inv(2)(p23q35) in anaplastic large-cell lymphoma induces constitutive anaplastic lymphoma kinase (ALK) tyrosine kinase activation by fusion to ATIC, an enzyme involved in purine nucleotide biosynthesis.
aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase
(7 times)
Biochemistry
(4 times)
AICAR (1 time)
ALK (1 time)
dNTP (1 time)
2001 Human 5-aminoimidazole-4-carboxamide ribonucleotide transformylase/inosine 5'-monophosphate cyclohydrolase. A bifunctional protein requiring dimerization for transformylase activity but not for cyclohydrolase activity.
AICAR transformylase/IMP cyclohydrolase
(5 times)
Biochemistry
(2 times)
AICAR (2 times)
AICA (1 time)
AICAR Tfase (1 time)
2004 AICA-ribosiduria: a novel, neurologically devastating inborn error of purine biosynthesis caused by mutation of ATIC.
acute trauma-induced coagulopathy
(2 times)
Hematologic Diseases
(1 time)
iSTBI (2 times)
CCTs (1 time)
TEG (1 time)
2019 Efficacy of Thromboelastography (TEG) in Predicting Acute Trauma-Induced Coagulopathy (ATIC) in Isolated Severe Traumatic Brain Injury (iSTBI).
Anti-oxidant Therapy In Chronic Renal Insufficiency
(2 times)
Internal Medicine
(1 time)
ADMA (1 time)
BA-FMD (1 time)
ccIMT (1 time)
2007 Effect of a treatment strategy consisting of pravastatin, vitamin E, and homocysteine lowering on carotid intima-media thickness, endothelial function, and renal function in patients with mild to moderate chronic kidney disease: results from the Anti-Oxidant Therapy in Chronic Renal Insufficiency (ATIC) Study.
5-Amino-4-imidazolecarboxamide ribonucleotide transformylase/IMP cyclohydrolase
(1 time)
Biochemistry
(1 time)
--- 2002 The kinetic mechanism of the human bifunctional enzyme ATIC (5-amino-4-imidazolecarboxamide ribonucleotide transformylase/inosine 5'-monophosphate cyclohydrolase). A surprising lack of substrate channeling.
adenosine ribonucleotide transformylase
(1 time)
Biomedical Research
(1 time)
MTHFR (1 time)
MTX (1 time)
RA (1 time)
2014 Prediction of methotrexate clinical response in Portuguese rheumatoid arthritis patients: implication of MTHFR rs1801133 and ATIC rs4673993 polymorphisms.
AICAR transformylase
(1 time)
Rheumatology
(1 time)
DF (1 time)
MTX (1 time)
2013 Fibroblasts from methotrexate-sensitive mice accumulate methotrexate polyglutamates but those from methotrexate-resistant mice do not.
10  AICAR transformylase/inosine monophosphate cyclohydrolase
(1 time)
Biochemistry
(1 time)
AICAR (1 time)
2003 Structure of avian AICAR transformylase with a multisubstrate adduct inhibitor beta-DADF identifies the folate binding site.
11  amino imidazole ribonucleotide transformylase
(1 time)
Rheumatology
(1 time)
MTHFR (1 time)
MTX (1 time)
ORs (1 time)
2006 Risk genotypes in folate-dependent enzymes and their association with methotrexate-related side effects in rheumatoid arthritis.