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Abbreviation: Akt
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Long Form No. Long Form Research Area Co-occurring Abbreviation PubMed/MEDLINE Info. (Year, Title)
activation of protein kinase B
(194 times)
Neoplasms
(36 times)
ERK (24 times)
mTOR (22 times)
PI3K (19 times)
2000 A potential mechanism for fumonisin B(1)-mediated hepatocarcinogenesis: cyclin D1 stabilization associated with activation of Akt and inhibition of GSK-3beta activity.
RAC-alpha serine/threonine-protein kinase
(36 times)
Neoplasms
(15 times)
PI3K (13 times)
EGFR (3 times)
ER (3 times)
2009 Preimplantation embryo development in the mouse requires the latency of TRP53 expression, which is induced by a ligand-activated PI3 kinase/AKT/MDM2-mediated signaling pathway.
associated with greater phosphorylation of protein kinase B
(21 times)
Molecular Biology
(5 times)
PI3K (4 times)
AMPK (2 times)
eNOS (2 times)
2008 Adenoviral cardiotrophin-1 transfer improves survival and early graft function after ischemia and reperfusion in rat small-for-size liver transplantation model.
Akt/protein kinase B
(14 times)
Neurology
(3 times)
EGF (2 times)
eNOS (2 times)
ERK (2 times)
1999 Epidermal growth factor protects epithelial cells against Fas-induced apoptosis. Requirement for Akt activation.
kinase and protein kinase B
(14 times)
Molecular Biology
(3 times)
ANPT (1 time)
AR (1 time)
CDK (1 time)
2001 Impaired muscle glycogen synthase in type 2 diabetes is associated with diminished phosphatidylinositol 3-kinase activation.
Akt kinase
(9 times)
Physiology
(3 times)
eNOS (3 times)
PI3K (3 times)
HFD (2 times)
2005 IL-2 increases human telomerase reverse transcriptase activity transcriptionally and posttranslationally through phosphatidylinositol 3'-kinase/Akt, heat shock protein 90, and mammalian target of rapamycin in transformed NK cells.
acting via the phosphatidylinositol-3-OH kinase (PI(3)K)-protein kinase B
(8 times)
Science
(2 times)
PI3K (3 times)
IGF-1 (2 times)
LPS (2 times)
2000 Constitutive expression of insulin-like growth factor-1 in epidermal basal cells of transgenic mice leads to spontaneous tumor promotion.
ATP-dependent tyrosine kinase
(8 times)
Neoplasms
(2 times)
FAK (3 times)
Cav-1 (2 times)
Cdc42 (2 times)
2001 Role of 14-3-3epsilon, c-Myc/Max, and Akt phosphorylation in HIV-1 gp 120-induced mesangial cell proliferation.
v-akt murine thymoma viral oncogene
(6 times)
Neurology
(3 times)
PI3K (4 times)
COX-2 (1 time)
FVPTC (1 time)
2009 Atrogin-1, MuRF1, and FoXO, as well as phosphorylated GSK-3beta and 4E-BP1 are reduced in skeletal muscle of chronic spinal cord-injured patients.
10  mitogen-activated protein kinase and protein kinase B
(5 times)
Neoplasms
(2 times)
3-MA (1 time)
4-PBA (1 time)
CHO (1 time)
2002 Heparin amplifies platelet-derived growth factor (PDGF)- BB-induced PDGF alpha -receptor but not PDGF beta -receptor tyrosine phosphorylation in heparan sulfate-deficient cells. Effects on signal transduction and biological responses.
11  activating RAC serine/threonine-protein kinase
(4 times)
Neoplasms
(1 time)
AD (1 time)
ARE (1 time)
EB (1 time)
2012 N-acetylcysteine enhances neuronal differentiation of P19 embryonic stem cells via Akt and N-cadherin activation.
12  Akt/PKB
(4 times)
Gastroenterology
(2 times)
BDL (1 time)
COX-2 (1 time)
EMT (1 time)
2004 Celecoxib-induced apoptosis in rat cholangiocarcinoma cells mediated by Akt inactivation and Bax translocation.
13  Ak mouse strain thymoma
(3 times)
Nutritional Sciences
(1 time)
bFGF (1 time)
CTGF (1 time)
DC (1 time)
2015 Laminin-rich blood vessels display activated growth factor signaling and act as the proliferation centers in Dupuytren's contracture.
14  activation of phosphoinositide 3'-kinase/protein kinase B
(2 times)
Chemistry
(1 time)
mTOR (2 times)
AIF (1 time)
Cd (1 time)
2014 Celastrol prevents cadmium-induced neuronal cell death via targeting JNK and PTEN-Akt/mTOR network.
15  addition, survival signaling molecules protein kinase B
(2 times)
Chemistry
(1 time)
ERK (1 time)
GRPs (1 time)
JNK (1 time)
2002 Activation of stress signaling molecules in bat brain during arousal from hibernation.
16  amino kinase terminal
(2 times)
Biochemistry
(1 time)
COX (1 time)
EGCG (1 time)
ERK (1 time)
2009 Role of caveolin-1 in EGCG-mediated protection against linoleic-acid-induced endothelial cell activation.
17  anti-apoptotic kinases protein kinase B
(2 times)
Nephrology
(1 time)
OGD (1 time)
TUNEL (1 time)
2003 Local anesthetics induce human renal cell apoptosis.
18  associated with a decrease in protein kinase B
(2 times)
Psychopharmacology
(1 time)
CaMKII (1 time)
D2R (1 time)
DISC1 (1 time)
2009 Potent in vivo antiangiogenic effects of GS-101 (5'-TATCCGGAGGGCTCGCCATGCTGCT-3'), an antisense oligonucleotide preventing the expression of insulin receptor substrate-1.
19  autophagic programmed cell death pathways through protein kinase B
(2 times)
Biological Science Disciplines
(2 times)
EPO (2 times)
2016 Regeneration in the nervous system with erythropoietin.
20  NF-kappaB, and protein kinase B
(2 times)
Clinical Laboratory Techniques
(1 time)
Bcl (1 time)
IL (1 time)
JNK (1 time)
2017 Quercetin prevents alcohol-induced liver injury through targeting of PI3K/Akt/nuclear factor-kappaB and STAT3 signaling pathway.
21  3-kinase(PI3K)-AKT serine/threonine kinase
(1 time)
Neoplasms
(1 time)
AIF (1 time)
MPM (1 time)
PI (1 time)
2018 Curcumin induces apoptosis and inhibits angiogenesis in murine malignant mesothelioma.
22  abates the interaction of CTMP and protein kinase B
(1 time)
Neoplasms
(1 time)
CREB (1 time)
CTMP (1 time)
MyHC (1 time)
2017 NDRG4 promotes myogenesis via Akt/CREB activation.
23  aberrant expression of genes related to the phosphatidyl-inositol-3'-kinase/protein kinase B
(1 time)
Brain
(1 time)
INPPL1 (1 time)
PI3K (1 time)
2003 Genetic alterations and aberrant expression of genes related to the phosphatidyl-inositol-3'-kinase/protein kinase B (Akt) signal transduction pathway in glioblastomas.
24  Abeta25-35 -inhibited protein kinase B
(1 time)
Neurology
(1 time)
AD (1 time)
alpha7nAChR (1 time)
ERK2 (1 time)
2014 Simvastatin exerts antiamnesic effect in Abeta25-35 -injected mice.
25  ability of BK to inhibit protein kinase B
(1 time)
Chemistry
(1 time)
BK (1 time)
2006 Modulation of bradykinin signaling by EP24.15 and EP24.16 in cultured trigeminal ganglia.
26  abolished the upregulation of phosphorylated‑protein kinase B
(1 time)
Molecular Biology
(1 time)
PEMFs (1 time)
RANKL (1 time)
2018 Pulsed electromagnetic fields inhibit osteoclast differentiation in RAW264.7 macrophages via suppression of the protein kinase B/mammalian target of rapamycin signaling pathway.
27  accompanied by an increased level of phosphorylated‑protein kinase B
(1 time)
Molecular Biology
(1 time)
I/R (1 time)
LC3 (1 time)
Pur (1 time)
2017 Puerarin attenuates myocardial hypoxia/reoxygenation injury by inhibiting autophagy via the Akt signaling pathway.
28  accompanied by phosphorylation of ERK1/2, phosphatidylinositol 3-kinase
(1 time)
Biochemistry
(1 time)
eNOS (1 time)
KRGE (1 time)
2007 Water extract of Korean red ginseng stimulates angiogenesis by activating the PI3K/Akt-dependent ERK1/2 and eNOS pathways in human umbilical vein endothelial cells.
29  accompanied with elevation of protein kinase B
(1 time)
Endocrinology
(1 time)
CA (1 time)
CREB (1 time)
ECM (1 time)
2015 Overexpression of the FoxO1 Ameliorates Mesangial Cell Dysfunction in Male Diabetic Rats.
30  accumulation of phosphorylated protein kinase B
(1 time)
Biochemistry
(1 time)
EGFR (1 time)
ERK (1 time)
HCS (1 time)
2012 Effects of CS-1 on A431 cell proliferation, cell cycle, and epidermal growth factor receptor signal transduction.
31  acid-mediated upregulation of protein kinase B
(1 time)
Biochemistry
(1 time)
PI3K (1 time)
2018 Betulinic acid improves insulin sensitivity, hyperglycemia, inflammation and oxidative stress in metabolic syndrome rats via PI3K/Akt pathways.
32  action demonstrated that cefminox inhibits the protein kinase B
(1 time)
Pharmacology
(1 time)
cAMP (1 time)
mTOR (1 time)
PAH (1 time)
2018 Cefminox, a Dual Agonist of Prostacyclin Receptor and Peroxisome Proliferator-Activated Receptor-Gamma Identified by Virtual Screening, Has Therapeutic Efficacy against Hypoxia-Induced Pulmonary Hypertension in Rats.
33  action on phosphorylated (p-)Protein Kinase B
(1 time)
Metabolism
(1 time)
AS160 (1 time)
CS (1 time)
EDL (1 time)
2019 Undercarboxylated osteocalcin improves insulin-stimulated glucose uptake in muscles of corticosterone-treated mice.
34  activate phosphatidylinositol 3-kinase/murine thymoma viral oncogene homolog 1
(1 time)
Nutritional Sciences
(1 time)
EFAs (1 time)
2011 Influence of polyunsaturated fatty acids and their metabolites on stem cell biology.
35  activate phosphatidylinositol-4,5-bisphosphate 3-kinase, protein kinase B
(1 time)
Gastroenterology
(1 time)
CRC (1 time)
FMNL (1 time)
HMGA (1 time)
2013 MicroRNA-137, an HMGA1 target, suppresses colorectal cancer cell invasion and metastasis in mice by directly targeting FMNL2.
36  activated by numerous genes and leads to protein kinase B
(1 time)
Molecular Biology
(1 time)
HIF (1 time)
PI3K (1 time)
2019 PI3K/Akt signaling transduction pathway, erythropoiesis and glycolysis in hypoxia (Review).
37  activated p-CaMKII could elicit the phosphorylation of protein kinase B
(1 time)
Biochemistry
(1 time)
CaMKII (1 time)
MAPK (1 time)
MIA (1 time)
2018 The Transient Receptor Potential Channel, Vanilloid 5, Induces Chondrocyte Apoptosis via Ca2+ CaMKII-Dependent MAPK and Akt/ mTOR Pathways in a Rat Osteoarthritis Model.
38  activated signalling via protein kinase B
(1 time)
Endocrinology
(1 time)
INSR (1 time)
sh (1 time)
2018 Evaluation of anti-insulin receptor antibodies as potential novel therapies for human insulin receptoropathy using cell culture models.
39  activated the phosphorylation of the target protein kinase B
(1 time)
Reproductive Medicine
(1 time)
ANXA8 (1 time)
EGF (1 time)
LIF (1 time)
2019 Annexin A8 (ANXA8) regulates proliferation of porcine endometrial cells via Akt signalling pathway.
40  activated threonine kinase
(1 time)
Cell Biology
(1 time)
FOXO3 (1 time)
siRNA (1 time)
TB (1 time)
2014 Forkhead box O3 (FOXO3) transcription factor mediates apoptosis in BCG-infected macrophages.
41  activates phosphatidylinositol 3-kinase and subsequently, protein kinase B
(1 time)
Pharmacology
(1 time)
IGF-1 (1 time)
2003 Akt is a molecular target for signal transduction therapy in brain ischemic insult.
42  activating phosphoinositidedependent kinase, protein kinase B
(1 time)
Chemistry
(1 time)
mTOR (1 time)
PI3Ks (1 time)
SARs (1 time)
2013 Recent developments of small molecule PI3K/mTOR dual inhibitors.
43  activation by flow of protein kinase B
(1 time)
Science
(1 time)
EC (1 time)
TrpRS (1 time)
2003 Biologically active fragment of a human tRNA synthetase inhibits fluid shear stress-activated responses of endothelial cells.
44  activation of c-Jun N-terminal kinase, protein kinase B
(1 time)
Neoplasms
(1 time)
--- 2002 G protein-coupled receptors provide survival signals in prostate cancer.
45  activation of caspases, and dephosphorylation of protein kinase B
(1 time)
Neoplasms
(1 time)
Bax (1 time)
Bcl-2 (1 time)
ERK (1 time)
2017 Isobavachalcone inhibits the proliferation and invasion of tongue squamous cell carcinoma cells.
46  activation of downstream signaling pathways including the protein kinase B
(1 time)
Neoplasms
(1 time)
mTOR (1 time)
PI3K (1 time)
RCC (1 time)
2009 Temsirolimus in the treatment of renal cell carcinoma associated with Xp11.2 translocation/TFE gene fusion proteins: a case report and review of literature.
47  activation of glucose metabolism-related signalling pathway via protein kinase B
(1 time)
Physiology
(1 time)
DHEA (1 time)
DHT (1 time)
STZ (1 time)
2009 DHEA improves impaired activation of Akt and PKC zeta/lambda-GLUT4 pathway in skeletal muscle and improves hyperglycaemia in streptozotocin-induced diabetes rats.
48  activation of kinases such as protein kinase B
(1 time)
MAP (1 time)
TRPV (1 time)
2018 Mechanisms involved in adenosine pharmacological preconditioning-induced cardioprotection.
49  activation of leptin-relevant signaling pathways involving protein kinase B
(1 time)
Endocrinology
(1 time)
LepBP (1 time)
2016 Impaired central leptin signaling and sensitivity in rainbow trout with high muscle adiposity.
50  activation of myocyte survival enzymes protein kinase B
(1 time)
Cardiovascular Diseases
(1 time)
JNK (1 time)
PARP (1 time)
PARP1 (1 time)
2018 Poly(ADP-ribose) Polymerase (PARP) and PARP Inhibitors: Mechanisms of Action and Role in Cardiovascular Disorders.
51  activation of neuroprotective kinases protein kinase B
(1 time)
Neurology
(1 time)
CHI (1 time)
ERK (1 time)
TBI (1 time)
2014 Angiotensin receptor type 2 activation induces neuroprotection and neurogenesis after traumatic brain injury.
52  activation of NF-kappaB by inhibiting upstream kinases
(1 time)
Rheumatology
(1 time)
MMP (1 time)
OA (1 time)
2009 Synergistic chondroprotective effects of curcumin and resveratrol in human articular chondrocytes: inhibition of IL-1beta-induced NF-kappaB-mediated inflammation and apoptosis.
53  activation of pro-survival factors such as protein kinase B
(1 time)
Cardiovascular Diseases
(1 time)
IHD (1 time)
VEGF (1 time)
2014 Impact of conditioning hyperglycemic on myocardial infarction rats: Cardiac cell survival factors.
54  activation of the downstream effector protein kinase B
(1 time)
Endocrine System Diseases
(1 time)
AMPK (1 time)
Ang II (1 time)
CKD (1 time)
2013 Insulin resistance and muscle metabolism in chronic kidney disease.
55  activation of the RAC-alpha serine/threonine-protein kinase
(1 time)
Clinical Laboratory Techniques
(1 time)
HGF (1 time)
MM (1 time)
2018 Antiproliferation activities of NK4 on multiple myeloma.
56  activation of the survival kinase Protein Kinase B
(1 time)
Neoplasms
(1 time)
PI3K (1 time)
PTEN (1 time)
2018 New Insights into Protein Kinase B/Akt Signaling: Role of Localized Akt Activation and Compartment-Specific Target Proteins for the Cellular Radiation Response.
57  activation of various signaling cascades such as protein kinase B
(1 time)
Nervous System Diseases
(1 time)
PI3K (1 time)
RA (1 time)
2015 Ouabain-Induced Signaling and Cell Survival in SK-N-SH Neuroblastoma Cells Differentiated by Retinoic Acid.
58  activation, is preserved, but insulin-stimulated protein kinase B
(1 time)
Endocrinology
(1 time)
IRS (1 time)
mTORC1 (1 time)
PI 3-kinase (1 time)
2008 Mechanisms of high-glucose/insulin-mediated desensitization of acute insulin-stimulated glucose transport and Akt activation.
59  active form of either PI3-K or PKB
(1 time)
Cell Biology
(1 time)
IGF-I (1 time)
PI3K (1 time)
SMCs (1 time)
1999 Changes in the balance of phosphoinositide 3-kinase/protein kinase B (Akt) and the mitogen-activated protein kinases (ERK/p38MAPK) determine a phenotype of visceral and vascular smooth muscle cells.
60  active inhibitors of protein kinase B
(1 time)
Chemistry
(1 time)
--- 2010 Discovery of 4-amino-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamides as selective, orally active inhibitors of protein kinase B (Akt).
61  activities and sustained protein kinase B
(1 time)
Biochemistry
(1 time)
MAPK (1 time)
2001 Oxidative preconditioning and apoptosis in L-cells. Roles of protein kinase B and mitogen-activated protein kinases.
62  activities in the phosphatidylinositol 3-kinase pathway
(1 time)
Proteome
(1 time)
--- 2003 A high-throughput quantitative multiplex kinase assay for monitoring information flow in signaling networks: application to sepsis-apoptosis.
63  activity and the promotion of phosphorylated‑protein kinase B
(1 time)
Molecular Biology
(1 time)
DM (1 time)
2016 Protective effect of thymoquinone improves cardiovascular function, and attenuates oxidative stress, inflammation and apoptosis by mediating the PI3K/Akt pathway in diabetic rats.
64  activity in the Neuro-2a cells through protein kinase B
(1 time)
Geriatrics
(1 time)
i.c.v (1 time)
IR (1 time)
PI3K (1 time)
2018 NO-Dependent Akt Inactivation by S-Nitrosylation as a Possible Mechanism of STZ-Induced Neuronal Insulin Resistance.
65  activity of Bax and inhibiting the protein kinase B
(1 time)
Neoplasms
(1 time)
DR (1 time)
ERS (1 time)
HOXA5 (1 time)
2017 Hoxa5 increases mitochondrial apoptosis by inhibiting Akt/mTORC1/S6K1 pathway in mice white adipocytes.
66  activity of its important downstream signaling targets protein kinase B
(1 time)
Gastroenterology
(1 time)
CCA (1 time)
GSK (1 time)
HGF (1 time)
2013 NK4 gene therapy inhibits HGF/Met-induced growth of human cholangiocarcinoma cells.
67  activity toward a peptide substrate reporter for protein kinase B
(1 time)
Chemistry Techniques, Analytical
(1 time)
CE-LIF (1 time)
2017 Interspecies comparison of peptide substrate reporter metabolism using compartment-based modeling.
68  acute insulin treatment, through the downstream kinase protein kinase B
(1 time)
Neurology
(1 time)
NE (1 time)
2010 Insulin reveals Akt signaling as a novel regulator of norepinephrine transporter trafficking and norepinephrine homeostasis.
69  acute lung injury via the serine/threonine kinase-protein kinase B
(1 time)
Critical Care
(1 time)
ERK (1 time)
2008 Serine/threonine kinase-protein kinase B and extracellular signal-regulated kinase regulate ventilator-induced pulmonary fibrosis after bleomycin-induced acute lung injury: a prospective, controlled animal experiment.
70  acute TBI, including protein kinase B
(1 time)
Neurology
(1 time)
LFPI (1 time)
PKC (1 time)
TBI (1 time)
2017 Traumatic Brain Injury Induces Alterations in Cortical Glutamate Uptake without a Reduction in Glutamate Transporter-1 Protein Expression.
71  addition, a significant decreased protein kinase B
(1 time)
Brain
(1 time)
AD (1 time)
PTP1B (1 time)
SOCS3 (1 time)
2018 Disruption of leptin signalling in a mouse model of Alzheimer's disease.
72  addition, berberine stimulated phosphorylation of protein kinase B
(1 time)
Neoplasms
(1 time)
PI3K (1 time)
pRb (1 time)
2014 Induction of G₂/M Arrest by Berberine via Activation of PI3K/Akt and p38 in Human Chondrosarcoma Cell Line.
73  addition, CSC treatment suppressed protein kinase-B
(1 time)
Neoplasms
(1 time)
PI3K (1 time)
2018 Chloroform fraction of Serratulae chinensis S. Moore suppresses proliferation and induces apoptosis via the phosphatidylinositide 3-kinase/Akt pathway in human gastric cancer cells.
74  addition, curcumin inhibited the phosphorylation of protein kinase B
(1 time)
Clinical Laboratory Techniques
(1 time)
Bax (1 time)
Bcl-2 (1 time)
mTOR (1 time)
2018 Curcumin inhibits proliferation and promotes apoptosis of breast cancer cells.
75  addition, GDNF significantly increased serine protein kinase B
(1 time)
Chemistry
(1 time)
GDNF (1 time)
GSK3beta (1 time)
PD (1 time)
2017 Intranasal Administration of GDNF Protects Against Neural Apoptosis in a Rat Model of Parkinson's Disease Through PI3K/Akt/GSK3beta Pathway.
76  addition, protein and mRNA expression levels of protein kinase B
(1 time)
Molecular Biology
(1 time)
HTy (1 time)
HUVECs (1 time)
mTOR (1 time)
2017 Hydroxytyrosol contributes to cell proliferation and inhibits apoptosis in pulsed electromagnetic fields treated human umbilical vein endothelial cells in vitro.
77  addition, the changes of the protein kinase B
(1 time)
Pulmonary Medicine
(1 time)
ERK (1 time)
MTT (1 time)
NSCLC (1 time)
2010 [The effects of Tumstatin185-191 on lung adenocarcinoma cell lines and the association with protein kinase B and extracellular regulated protein kinase activation].
78  addition, the expressions of phosphorylated protein kinase B
(1 time)
Pharmacology
(1 time)
eNOS (1 time)
RVO (1 time)
2017 Effects of kallidinogenase on retinal edema and size of non-perfused areas in mice with retinal vein occlusion.
79  addition, the phosphorylation of FAK, paxillin and protein kinase B
(1 time)
Physiology
(1 time)
FAK (1 time)
Lys (1 time)
SCs (1 time)
2019 Lysine-induced swine satellite cell migration is mediated by the FAK pathway.
80  Additionally, galangin reduced protein kinase B
(1 time)
Biology
(1 time)
PIP3 (1 time)
2018 Galangin inhibits the cell progression and induces cell apoptosis through activating PTEN and Caspase-3 pathways in retinoblastoma.
81  Additionally, high glucose decreased cell viability, prevented serine-threonine kinase
(1 time)
Cardiology
(1 time)
DCM (1 time)
p-Akt and p-FoxO3a (1 time)
RSV (1 time)
2017 Resveratrol Ameliorates Cardiac Dysfunction by Inhibiting Apoptosis via the PI3K/Akt/FoxO3a Pathway in a Rat Model of Diabetic Cardiomyopathy.
82  Additionally, the expression levels of several RAC-alpha serine/threonine kinase
(1 time)
Neoplasms
(1 time)
Bcl-2 (1 time)
PI3K (1 time)
2017 Combination of cecropinXJ and LY294002 induces synergistic cytotoxicity, and apoptosis in human gastric cancer cells via inhibition of the PI3K/Akt signaling pathway.
83  adenosine triphosphate-dependent tyrosine kinase
(1 time)
Neoplasms
(1 time)
HCC (1 time)
HIF-1 (1 time)
PI3K (1 time)
2010 PTEN regulates angiogenesis and VEGF expression through phosphatase-dependent and -independent mechanisms in HepG2 cells.
84  adenovirus expressing a dominant-negative mutant of protein kinase B
(1 time)
Physiology
(1 time)
CaM (1 time)
FS (1 time)
MOI (1 time)
2007 Signalling mechanisms in contraction-mediated stimulation of intracellular NO production in cat ventricular myocytes.
85  adipocytes at the level of insulin receptor, proteinkinase B
(1 time)
Biochemistry
(1 time)
sDPP4 (1 time)
2016 Reduced DPP4 activity improves insulin signaling in primary human adipocytes.
86  administration induced a significant phosphorylation of prosurvival protein kinase B
(1 time)
Biomedical Research
(1 time)
IRI (1 time)
PEG 35 (1 time)
PEGs (1 time)
2015 Protective Effect of Intravenous High Molecular Weight Polyethylene Glycol on Fatty Liver Preservation.
87  administration significantly enhanced protein kinase B
(1 time)
Chemistry
(1 time)
BCCAO (1 time)
mAChR (1 time)
MEC (1 time)
2017 The T-type calcium channel enhancer SAK3 inhibits neuronal death following transient brain ischemia via nicotinic acetylcholine receptor stimulation.
88  administration significantly promoted the phosphorylation levels of protein kinase B
(1 time)
Behavioral Sciences
(1 time)
GSK-3beta (1 time)
IRS-1 (1 time)
SOCS2 (1 time)
2017 Paeoniflorin ameliorates cognitive dysfunction via regulating SOCS2/IRS-1 pathway in diabetic rats.
89  ADSC treatment had a lower expression of protein kinase B
(1 time)
Rheumatology
(1 time)
ADSC (1 time)
PBS (1 time)
SLE (1 time)
2019 Allogeneic adipose-derived stem cells suppress mTORC1 pathway in a murine model of systemic lupus erythematosus.
90  AF also induced protein kinase B
(1 time)
Molecular Biology
(1 time)
--- 2007 Dose-response transition from cell cycle arrest to apoptosis with selective degradation of Mdm2 and p21WAF1/CIP1 in response to the novel anticancer agent, aminoflavone (NSC 686,288).
91  affecting the total protein kinase B
(1 time)
Biochemistry
(1 time)
ERK (1 time)
FH (1 time)
HK (1 time)
2011 5-Formylhonokiol exerts anti-angiogenesis activity via inactivating the ERK signaling pathway.
92  affects the regulation of protein kinase B
(1 time)
Geriatrics
(1 time)
AMPK (1 time)
CaN (1 time)
EDL (1 time)
2010 Effects of aging and gender on muscle mass and regulation of Akt-mTOR-p70s6k related signaling in the F344BN rat model.
93  affects various elements of the protein kinase B
(1 time)
Sports Medicine
(1 time)
FSK (1 time)
INS (1 time)
P/T (1 time)
2009 Forskolin attenuates the action of insulin on the Akt-mTOR pathway in human skeletal muscle.
94  After pretreatment of protein kinase B
(1 time)
Medicine
(1 time)
APP (1 time)
CRMP2 (1 time)
HI (1 time)
2015 [The Involvement of CRMP-2 on Axonal and Dendrictic Injury after Hypoxic-Ischemic Brain Injury in Neonatal Rat].
95  After the inhibition of protein kinase B
(1 time)
Biochemistry
(1 time)
NF-kappaB (1 time)
p38 MAPK (1 time)
PKC (1 time)
2003 Pretreatment with PKC inhibitor triggers TNF-alpha induced apoptosis in TNF-alpha-resistant B16 melanoma BL6 cells.
96  after transient forebrain ischemia through phosphatidylinositol 3-kinase-protein kinase B
(1 time)
Brain
(1 time)
--- 2002 Decreased akt activity is associated with activation of forkhead transcription factor after transient forebrain ischemia in gerbil hippocampus.
97  AGC family of protein kinases, such as protein kinase B
(1 time)
Neoplasms
(1 time)
PKC (1 time)
2013 3-Phosphoinositide-dependent protein kinase-1 as an emerging target in the management of breast cancer.
98  AGC protein kinase family including protein kinase B
(1 time)
Biochemistry
(1 time)
mPDK-1 (1 time)
2002 Substitution of the autophosphorylation site Thr516 with a negatively charged residue confers constitutive activity to mouse 3-phosphoinositide-dependent protein kinase-1 in cells.
99  agonist CPA causes protein kinase B
(1 time)
Pharmacology
(1 time)
EGFR (1 time)
OGD (1 time)
PTX (1 time)
2009 Adenosine A(1) receptor-mediated transactivation of the EGF receptor produces a neuroprotective effect on cortical neurons in vitro.
100  AGS cells, oxaliplatin treatment promoted both protein kinase B
(1 time)
Gastroenterology
(1 time)
FasL (1 time)
NF-kappaB (1 time)
2011 LY294002 potentiates the anti-cancer effect of oxaliplatin for gastric cancer via death receptor pathway.