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Abbreviation: CD4
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Long Form No. Long Form Research Area Co-occurring Abbreviation PubMed/MEDLINE Info. (Year, Title)
cluster of differentiation 4
(167 times)
Medicine
(29 times)
HIV (52 times)
ART (15 times)
CD8 (13 times)
1992 Inhibition of phosphatidylserine synthesis induced by a CD4 mAb, B66.6 in Jurkat T cells.
CD4+ T-lymphocyte
(41 times)
Medicine
(10 times)
ART (11 times)
HIV (9 times)
VL (5 times)
1991 HIV prevalence, immunosuppression, and drug resistance in patients with tuberculosis in an area endemic for AIDS.
CD4 cell count
(24 times)
Acquired Immunodeficiency Syndrome
(10 times)
ART (10 times)
VL (6 times)
CI (5 times)
1992 Effect of CD4+ cell count measurement variability on staging HIV-1 infection.
CD4+ T-cell
(20 times)
Medicine
(5 times)
ART (8 times)
CAA (2 times)
HIV (2 times)
2005 Increased circulating interleukin-7 levels in HIV-1-infected women.
CD4 lymphocyte count
(11 times)
Acquired Immunodeficiency Syndrome
(2 times)
ART (2 times)
cART (2 times)
CI (2 times)
1995 Prospective cohort study of the effect of pregnancy on the progression of human immunodeficiency virus infection. The Groupe d'Epidemiologie Clinique Du SIDA en Aquitaine.
CD4(+) T cells/L
(6 times)
Allergy and Immunology
(2 times)
ART (4 times)
Ig (2 times)
OPA (2 times)
2008 Pharmacy refill adherence compared with CD4 count changes for monitoring HIV-infected adults on antiretroviral therapy.
cluster determinant 4
(4 times)
Biochemistry
(2 times)
DPC (2 times)
HIV (1 time)
HIV-1 (1 time)
2007 Structural characterization of the transmembrane and cytoplasmic domains of human CD4.
CD4 count
(3 times)
Acquired Immunodeficiency Syndrome
(2 times)
ADIs (1 time)
aRR (1 time)
cART (1 time)
2004 Absolute CD4 vs. CD4 percentage for predicting the risk of opportunistic illness in HIV infection.
CD4+ T-lymphocyte cell
(3 times)
Communicable Diseases
(2 times)
AEs (2 times)
OR (2 times)
cART (1 time)
2015 Immunogenicity and safety of meningococcal C conjugate vaccine in children and adolescents infected and uninfected with HIV in Rio de Janeiro, Brazil.
10  CD3+, L3T4
(2 times)
Allergy and Immunology
(1 time)
DTH (1 time)
1989 Sequential activity of gamma-delta T-cell receptor bearing lymphocytes, specific T-cell factors, and alpha-beta T-cell receptor bearing T-cells: a hypothesis.
11  CD4(+) T
(2 times)
Communicable Diseases
(1 time)
cART (1 time)
EFV (1 time)
HBV (1 time)
2010 Antiretroviral therapy hepatotoxicity: Prevalence, risk factors, and clinical characteristics in a cohort of Han Chinese.
12  CD4-positive T-lymphocyte
(2 times)
Virology
(1 time)
CD8 (1 time)
1999 [The prognostic value of virology and immunology markers in Chinese HIV-1 infected people].
13  CD4lo
(2 times)
Allergy and Immunology
(2 times)
--- 1993 The expression of CD4 by T cell precursors resident in both the thymus and the bone marrow.
14  C and those pretreated with anti-L3T4
(1 time)
Allergy and Immunology
(1 time)
GVHD (1 time)
mAb (1 time)
1993 Roles of CD8+ and CD4+ cells on lethal graft-versus-host disease in nude mice.
15  C8166 and HeLa-T4
(1 time)
Virology
(1 time)
HIV-1 (1 time)
mAb (1 time)
PAN (1 time)
1996 Two neutralizing anti-V3 monoclonal antibodies act by affecting different functions of human immunodeficiency virus type 1.
16  capped by Phe43
(1 time)
Chemistry
(1 time)
--- 2012 Structure-based design, synthesis, and characterization of dual hotspot small-molecule HIV-1 entry inhibitors.
17  cases showed the expression of T4
(1 time)
Hematology
(1 time)
ATL (1 time)
Sups (1 time)
1989 [Expressions of 2H4 and 4B4 antigens on ATL cells].
18  CD3 and either the L3T4
(1 time)
Transplantation
(1 time)
--- 1990 Antilymphocytic antibodies and bone marrow transplantation. XI. Evidence that reduced Thy-1 expression in Thy-1.1 mice prevents suppression of graft-versus-host disease with anti-Thy-1 monoclonal antibodies.
19  CD4 absolute counts
(1 time)
Acquired Immunodeficiency Syndrome
(1 time)
Hb (1 time)
2017 CD4 Lymphocyte Enumeration and Hemoglobin Assessment Aid for Priority Decisions: A Multisite Evaluation of the BD FACSPresto™ System.
20  CD4 antigens
(1 time)
Pharmacology
(1 time)
bR (1 time)
CCR5 (1 time)
HIV-1 gp120 (1 time)
2000 Molecular modeling on human CCR5 receptors and complex with CD4 antigens and HIV-1 envelope glycoprotein gp120.
21  CD4 count and hemoglobin concentration against the FACSCount
(1 time)
Medicine
(1 time)
ART (1 time)
2019 Performance of the BD-FACS Presto for CD4 count and hemoglobin measurement in a district hospital and rural laboratory in Ghana.
22  CD4 count was significantly associated with lower odds of retention
(1 time)
Acquired Immunodeficiency Syndrome
(1 time)
AOR (1 time)
ART (1 time)
CI (1 time)
2011 Retention in HIV care for individuals not yet eligible for antiretroviral therapy: rural KwaZulu-Natal, South Africa.
23  CD4 counts and viral loads were performed and their values
(1 time)
Health Services
(1 time)
HIV (1 time)
2007 A comparison of HIV health services utilization measures in a marginalized population: self-report versus medical records.
24  CD4 help and why
(1 time)
Allergy and Immunology
(1 time)
--- 2009 Recall responses by helpless memory CD8+ T cells are restricted by the up-regulation of PD-1.
25  CD4 knockout
(1 time)
Allergy and Immunology
(1 time)
MAIDS (1 time)
2001 B cell immunodeficiency fails to develop in CD4-deficient mice infected with BM5: murine AIDS as a multistep disease.
26  CD4 molecule
(1 time)
Veterinary Medicine
(1 time)
CD8A (1 time)
CD8B (1 time)
GZMA (1 time)
2014 Transcriptome analysis reveals an activation of major histocompatibility complex 1 and 2 pathways in chicken trachea immunized with infectious laryngotracheitis virus vaccine.
27  CD4 or CD8
(1 time)
Dermatology
(1 time)
EBV (1 time)
LMP1 (1 time)
TCR (1 time)
1997 An autopsy case of angioimmunoblastic T-cell lymphoma with a high content of epithelioid cells in the lymph node: immunohistochemical and genomic analyses.
28  CD4 positive cells
(1 time)
Pathology
(1 time)
--- 1991 The evolution of the interstitial infiltrate in rejecting rat renal allografts: with particular reference to the production of gamma-interferon.
29  CD4 T cells to CD8 T cells
(1 time)
Allergy and Immunology
(1 time)
--- 2002 Linkage analysis of variations in CD4:CD8 T cell subsets between C57BL/6 and DBA/2.
30  CD4 to CD8 lymphocyte subset ratio
(1 time)
Internal Medicine
(1 time)
BALF (1 time)
2003 Rhinitis/Bronchopneumonia syndrome in Irish Wolfhounds.
31  CD4 zeta
(1 time)
Allergy and Immunology
(1 time)
NK (1 time)
1995 Chimeric zeta-receptors direct human natural killer (NK) effector function to permit killing of NK-resistant tumor cells and HIV-infected T lymphocytes.
32  CD4(+)
(1 time)
Allergy and Immunology
(1 time)
TCR (1 time)
2016 Avidity of human T cell receptor engineered CD4(+) T cells drives T-helper differentiation fate.
33  CD4(+)T lymphocyte cell counts
(1 time)
Communicable Diseases
(1 time)
ART (1 time)
2016 [Survival effect after antiretroviral treatment initiating at different times on AIDS patients in Henan province, 2002-2014].
34  CD4(p55)
(1 time)
Genetics, Medical
(1 time)
DRPLA (1 time)
PTHLH (1 time)
1996 Precise chromosomal locations of the genes for dentatorubral-pallidoluysian atrophy (DRPLA), von Willebrand factor (F8vWF) and parathyroid hormone-like hormone (PTHLH) in human chromosome 12p by deletion mapping.
35  CD4+ and CD19+ subsets
(1 time)
Allergy and Immunology
(1 time)
--- 1993 In vitro primary immunization of B lymphocytes for producing human monoclonal antibodies against tumor-associated antigens.
36  CD4+ and CD8+ T cells occurred in mucosa-associated tissues
(1 time)
Allergy and Immunology
(1 time)
LP (1 time)
MC (1 time)
MLN (1 time)
1993 Characterization of T and B cells isolated from mucosa-associated tissues of the rhesus macaque.
37  CD4+ CD25+ cells from healthy HSV-2-infected humans on recall proliferative
(1 time)
Virology
(1 time)
HSV-1 (1 time)
2006 Human CD4+ CD25 high cells suppress proliferative memory lymphocyte responses to herpes simplex virus type 2.
38  CD4+ cells in the epithelium
(1 time)
Ophthalmology
(1 time)
--- 1997 Characterisation of the normal conjunctival leukocyte population.
39  CD4+ lymphocyte counts in blood
(1 time)
Neurology
(1 time)
CDC (1 time)
IDUs (1 time)
1999 Pain in ambulatory HIV-infected patients with and without intravenous drug use.
40  CD4+ T
(1 time)
Gastroenterology
(1 time)
AIDS (1 time)
cART (1 time)
NVP (1 time)
2010 [Nevirapine related hepatotoxicity: the prevalence and risk factors in a cohort of ART naive Han Chinese with AIDS].
41  CD4+ T cells in mice by treatment with anti-L3T4
(1 time)
Neoplasms
(1 time)
MAP (1 time)
1998 Vaccination with multiple antigen peptide as rejection antigen peptide in murine leukemia.
42  CD4+ T-cell lymphocytes
(1 time)
Acquired Immunodeficiency Syndrome
(1 time)
ARV (1 time)
2004 Immune status and uptake of antiretroviral interventions to prevent mother-to-child transmission of HIV-1 in Africa.
43  CD4+ T-helper cell predominance
(1 time)
Allergy and Immunology
(1 time)
GH (1 time)
LH (1 time)
2016 Granulomatous and lymphocytic hypophysitis - are they immunologically distinct?
44  CD4+ Th cells in anti-L3T4
(1 time)
Biology
(1 time)
--- 1992 Induction of T helper cells and cytokines for mucosal IgA responses.
45  CD4+T and on CD8+T cells was higher in HIV
(1 time)
Cell Biology
(1 time)
HIV (1 time)
NP (1 time)
2008 Immunologic features of HIV-1-infected women on HAART at delivery.
46  CD4+T cell-derived
(1 time)
Multiple Sclerosis
(1 time)
--- 2020 Concentrations of plasma-borne extracellular particles differ between multiple sclerosis disease courses and compared to healthy controls.
47  CD4-APC
(1 time)
Cell Biology
(1 time)
APC (1 time)
CD8 (1 time)
Cy5.5 (1 time)
2001 Cell analysis system based on immunomagnetic cell selection and alignment followed by immunofluorescent analysis using compact disk technologies.
48  CD4-bound
(1 time)
Cell Membrane
(1 time)
--- 2020 CD4-binding obstacles in conformational transitions and allosteric communications of HIV gp120.
49  CD4-BR
(1 time)
Medicine
(1 time)
HIV (1 time)
VNA (1 time)
1992 [Peptides from the principal neutralizing and CD4-binding domain: similar immunoreactive properties and structure pattern].
50  CD4-deficient
(1 time)
Laboratory Animal Science
(1 time)
CD8 (1 time)
TCR (1 time)
wpi (1 time)
2013 Effect of immunodeficiency on MPV shedding and transmission.
51  CD4-DNA
(1 time)
Allergy and Immunology
(1 time)
rCD4 (1 time)
1997 DNA-based immunization induces anti-CD4 antibodies directed primarily to native epitopes.
52  CD4-independent-HIGH
(1 time)
Virology
(1 time)
--- 2007 CD4-independent use of the CCR5 receptor by sequential primary SIVsm isolates.
53  CD4-induced shedding
(1 time)
Virology
(1 time)
HIV-1 (1 time)
1994 Increase in soluble CD4 binding to and CD4-induced dissociation of gp120 from virions correlates with infectivity of human immunodeficiency virus type 1.
54  CD4-intermediate cells
(1 time)
Virology
(1 time)
ADCC (1 time)
CD4i (1 time)
Env (1 time)
2019 CD4- and Time-Dependent Susceptibility of HIV-1-Infected Cells to Antibody-Dependent Cellular Cytotoxicity.
55  CD4-low cells
(1 time)
Virology
(1 time)
ADCC (1 time)
CD4i (1 time)
Env (1 time)
2019 CD4- and Time-Dependent Susceptibility of HIV-1-Infected Cells to Antibody-Dependent Cellular Cytotoxicity.
56  CD4-only
(1 time)
Medicine
(1 time)
FDO (1 time)
HAART (1 time)
NNRTI (1 time)
2013 Switching HIV treatment in adults based on CD4 count versus viral load monitoring: a randomized, non-inferiority trial in Thailand.
57  CD4-positive T cells and CD68-positive monocytes/macrophages
(1 time)
Allergy and Immunology
(1 time)
IFN-gamma (1 time)
IL-4 (1 time)
2001 Presence of IFN-gamma and IL-4 in human periapical granulation tissues and regeneration tissues.
58  CD4-transduced glioma cell line
(1 time)
Virology
(1 time)
GPCRs (1 time)
HIV-1 (1 time)
HIV-2 (1 time)
2008 A formylpeptide receptor, FPRL1, acts as an efficient coreceptor for primary isolates of human immunodeficiency virus.
59  CD4-VLPs
(1 time)
Science
(1 time)
bNAb (1 time)
sCD4 (1 time)
2020 Nanoparticles presenting clusters of CD4 expose a universal vulnerability of HIV-1 by mimicking target cells.
60  CD4.Q421stop
(1 time)
Science
(1 time)
ER (1 time)
1991 Signals for retention of transmembrane proteins in the endoplasmic reticulum studied with CD4 truncation mutants.
61  CD4/CD8, high CD3
(1 time)
Medicine
(1 time)
BAL (1 time)
FC (1 time)
PBL (1 time)
1997 [Use of flow cytometry in evaluation of cellular changes in interstitial lung diseases].
62  CD45RA+
(1 time)
Internal Medicine
(1 time)
DM (1 time)
OSA (1 time)
1999 [Latent autoimmune (type I) diabetes mellitus in adults. Part. II. Association of HLA antigens, status of cellular immunity and occurrence of other autoimmune diseases].
63  CD4BL
(1 time)
Acquired Immunodeficiency Syndrome
(1 time)
BL (1 time)
RC (1 time)
2009 Replication capacity in relation to immunologic and virologic outcomes in HIV-1-infected treatment-naive subjects.
64  CD4brightCD8dim
(1 time)
Allergy and Immunology
(1 time)
PBMC (1 time)
PHA (1 time)
TCR (1 time)
2001 Upregulation of CD4 on CD8+ T cells: CD4dimCD8bright T cells constitute an activated phenotype of CD8+ T cells.
65  CD4CTX
(1 time)
Biological Science Disciplines
(1 time)
--- 2018 The transcription factors Runx3 and ThPOK cross-regulate acquisition of cytotoxic function by human Th1 lymphocytes.
66  CD4CYTO
(1 time)
Biochemistry
(1 time)
HIV (1 time)
TFE (1 time)
1998 Solution structure of the cytoplasmic domain of the human CD4 glycoprotein by CD and 1H NMR spectroscopy: implications for biological functions.
67  CD4D12
(1 time)
Biochemistry
(1 time)
sCD4 (1 time)
2011 Design and characterization of stabilized derivatives of human CD4D12 and CD4D1.
68  CD4DAF
(1 time)
Biotechnology
(1 time)
DAF (1 time)
GPI (1 time)
1992 Endocytosis of glycophospholipid-anchored and transmembrane forms of CD4 by different endocytic pathways.
69  CD4high8int
(1 time)
Allergy and Immunology
(1 time)
--- 1995 Intermediate steps in thymic positive selection. Generation of CD4-8+ T cells in culture from CD4+8+, CD4int8+, and CD4+8int thymocytes with up-regulated levels of TCR-CD3.
70  CD4INTRA
(1 time)
Allergy and Immunology
(1 time)
HHV-7 (1 time)
1997 Human herpesvirus 7 induces the down-regulation of CD4 antigen in lymphoid T cells without affecting p56lck levels.
71  CD4L-1
(1 time)
Allergy and Immunology
(1 time)
--- 2011 Clonal growth of carp (Cyprinus carpio) T cells in vitro.
72  CD4Ms
(1 time)
Virology
(1 time)
Envs (1 time)
2017 Induction of a Tier-1-Like Phenotype in Diverse Tier-2 Isolates by Agents That Guide HIV-1 Env to Perturbation-Sensitive, Nonnative States.
73  CD4mut
(1 time)
Biochemistry
(1 time)
DPC (1 time)
PRE (1 time)
2010 NMR structure of the transmembrane and cytoplasmic domains of human CD4 in micelles.
74  CD4PEP1
(1 time)
Biochemistry
(1 time)
CD4D12 (1 time)
2005 Protein minimization of the gp120 binding region of human CD4.
75  CD4SP
(1 time)
Transplantation
(1 time)
BMCs (1 time)
CD8 (1 time)
PBLs (1 time)
2004 CD8 T cell of donor splenocyte mixed with bone marrow cells is more effective than CD4 T cell for induction of donor-specific tolerance in sublethally irradiated mice.
76  CD4SURF
(1 time)
Allergy and Immunology
(1 time)
HHV-7 (1 time)
1997 Human herpesvirus 7 induces the down-regulation of CD4 antigen in lymphoid T cells without affecting p56lck levels.
77  Cell depletion experiments indicated that L3T4
(1 time)
Allergy and Immunology
(1 time)
B cells (1 time)
1988 Human recombinant IL-6/B cell stimulatory factor 2 augments murine antigen-specific antibody responses in vitro and in vivo.
78  Cell Differentiation 4
(1 time)
Women's Health
(1 time)
AOR (1 time)
ART (1 time)
CA (1 time)
2018 Low uptake of cervical cancer screening among HIV positive women in Gondar University referral hospital, Northwest Ethiopia: cross-sectional study design.
79  cell subsets differed with age of thymus graft; i.e. L3T4
(1 time)
Geriatrics
(1 time)
--- 1991 Age influence on the thymic capacity to promote differentiation of T cells: induction of different composition of T cell subsets by aging thymus.
80  Cell-depletion studies revealed that L3T4
(1 time)
Allergy and Immunology
(1 time)
PFC (1 time)
SRBC (1 time)
1992 Enhancement of in vitro and in vivo antigen-specific antibody responses by interleukin 11.
81  cells depleted of OKT4
(1 time)
Allergy and Immunology
(1 time)
CD8 (1 time)
Df (1 time)
IL-2 (1 time)
1989 Allergen-specific induction of interleukin-2 (IL-2) responsiveness in lymphocytes from children with asthma. I. Antigen specificity and initial events of the induction.
82  cells lyse L. monocytogenes primed macrophages; L3T4+
(1 time)
Allergy and Immunology
(1 time)
--- 1988 Listeria monocytogenes specific T-cell lines and clones.
83  cells were blocked by anti-L3T4
(1 time)
Allergy and Immunology
(1 time)
CD8 (2 times)
CTL (1 time)
mAb (1 time)
1991 CD4-CD8- T cell receptor alpha beta T cells: generation of an in vitro major histocompatibility complex class I specific cytotoxic T lymphocyte response and allogeneic tumor rejection.
84  cells, lacking detectable expression of Thy 1, L3T4
(1 time)
Allergy and Immunology
(1 time)
ADCC (1 time)
CP (1 time)
NA (1 time)
1990 Characterization of Corynebacterium parvum-induced suppressor cells of mouse NK and ADCC activity.
85  channel from the solvent to the iron atom, and Phe46
(1 time)
Biochemistry
(1 time)
--- 1996 Mechanism of hydrogen cyanide binding to myoglobin.
86  children of 43%, double positive helper
(1 time)
Traumatology
(1 time)
PHA (1 time)
1991 Alterations of the immune system following splenectomy in childhood.
87  clones essentially proved that the T cell-specific molecules T4
(1 time)
Immune System Diseases
(1 time)
IL-2 (1 time)
MoAbs (1 time)
TCR (1 time)
2012 Toward a molecular understanding of adaptive immunity: a chronology - part II.
88  clones from L. monocytogenes infected mice: L3T4+
(1 time)
Allergy and Immunology
(1 time)
--- 1988 Listeria monocytogenes specific T-cell lines and clones.
89  clones indicated comparable frequencies for OKT4
(1 time)
Allergy and Immunology
(1 time)
IFN-gamma (1 time)
1988 Limiting-dilution analysis of T cells extracted from solid human lung tissue: comparison of precursor frequencies for proliferative responses and lymphokine production between lung and blood T cells from individual donors.
90  cluster difference 4
(1 time)
Public Health
(1 time)
AC (1 time)
ARC (1 time)
HIV (1 time)
1992 Pathological status and therapy of HIV-infected hemophiliacs in Japan.
91  cluster of differentiation 4 lymphocyte
(1 time)
Medicine
(1 time)
ASV (1 time)
cART (1 time)
DAA (1 time)
2019 Antiviral therapy for HCV in hemophilia A patients with HIV-1 co-infection.
92  combination with the monoclonal antibodies IAd-FITC, L3T4
(1 time)
Biotechnology
(1 time)
ACF (1 time)
1996 Detection of cell-surface antigens using antibody-conjugated fluorospheres (ACF): application for six-color immunofluorescence.
93  compared to SBU-T4
(1 time)
Allergy and Immunology
(1 time)
BTV (1 time)
BTV-10 (1 time)
BTV-17 (1 time)
1990 T lymphocyte subset alterations following bluetongue virus infection in sheep and cattle.
94  composed of a mixture of OPD4
(1 time)
Dermatology
(1 time)
PPE (1 time)
1991 Pigmented purpuric eruptions: immunopathologic studies supportive of a common immunophenotype.
95  confined to the T4
(1 time)
Allergy and Immunology
(1 time)
LTP (1 time)
1990 Substance P increases and prolongs increased output of T4 (CD4) lymphocytes from lymph nodes of sheep in vivo: is it a mediator of immunological memory?
96  confirmed that mRNA for L3T4
(1 time)
Allergy and Immunology
(1 time)
--- 1989 Characterization of a CD4(L3T4)-positive cytotoxic T cell clone that is restricted by class I major histocompatibility complex antigen on FBL-3 tumor cell.
97  CsA-treated mice lacked the SP L3T4
(1 time)
Allergy and Immunology
(1 time)
CsA (1 time)
DN (1 time)
DP (1 time)
1989 Cyclosporine A prevents the generation of single positive mature T cells in newborn mice.
98  CTL responses was related to a selective defect in Ly-4
(1 time)
Allergy and Immunology
(1 time)
--- 1989 Functional and phenotypic alterations in T cell subsets during the course of MAIDS, a murine retrovirus-induced immunodeficiency syndrome.
99  CTL were observed in B6 mice treated with anti-L3T4
(1 time)
Allergy and Immunology
(1 time)
CD8 (2 times)
CTL (1 time)
mAb (1 time)
1991 CD4-CD8- T cell receptor alpha beta T cells: generation of an in vitro major histocompatibility complex class I specific cytotoxic T lymphocyte response and allogeneic tumor rejection.
100  cytokine (interleukin-4/interleukin-2)-producing
(1 time)
Hematology
(1 time)
NKT (1 time)
2002 Trafficking machinery of NKT cells: shared and differential chemokine receptor expression among V alpha 24(+)V beta 11(+) NKT cell subsets with distinct cytokine-producing capacity.