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■ Search Result - Abbreviation : COX-2

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Abbreviation: COX-2
Appearance Frequency: 11341 time(s)
Long forms: 55

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Long Form No. Long Form Research Area Co-occurring Abbreviation PubMed/MEDLINE Info. (Year, Title)
cyclooxygenase-2
(11204 times)
Neoplasms
(1752 times)
iNOS (1685 times)
PGE2 (1159 times)
LPS (1135 times)
1993 Interleukin-1 differentially modulates chondrocyte expression of cyclooxygenase-2 and phospholipase A2.
contribution of cyclooxygenase-2
(42 times)
Biochemistry
(9 times)
PGE2 (6 times)
3'-UTR (2 times)
CCI (2 times)
1999 Role of interleukin 1 in the regulation of cyclooxygenase gene expression in rat endometrial stromal cells.
cyclo-oxygenase 2 inhibitors
(14 times)
Epidemiology
(4 times)
NSAIDs (6 times)
GI (2 times)
NSAID (2 times)
2001 [Selective cyclooxygenase 2 inhibitors (COX-2)].
cyclooxygenase isoform 2
(9 times)
Veterinary Medicine
(3 times)
AA (1 time)
ASAC (1 time)
DGLA (1 time)
1999 [Aspirin].
cost-effectiveness of cyclooxygenase-2
(5 times)
Pain Management
(1 time)
NSAIDs (3 times)
QALY (3 times)
GI (2 times)
2003 Pharmacoeconomic modeling of prior-authorization intervention for COX-2 specific inhibitors in a 3-tier copay plan.
characterization of cyclooxygenase-2
(4 times)
Chemistry
(1 time)
COX-1 (1 time)
PGs (1 time)
2001 An immunohistological study on cyclooxygenase-2 in human dental pulp.
anti-cyclo-oxygenase-2
(3 times)
Histocytochemistry
(1 time)
ACE (1 time)
AQU-1 (1 time)
COX-1 (1 time)
2001 Melatonin reduces dinitrobenzene sulfonic acid-induced colitis.
class of selective cyclooxygenase-2
(3 times)
Medicine
(1 time)
COX-1 (1 time)
ED50 (1 time)
HWB (1 time)
1999 Discovery of a new class of selective cyclooxygenase-2 (COX-2) inhibitor that covalently modifies the isozyme.
constitutive overexpression of cyclooxygenase-2
(3 times)
Neoplasms
(3 times)
IGF-I (1 time)
IGFBP-3 (1 time)
NSCLC (1 time)
2003 Mouse skin as a model for cancer chemoprevention by nonsteroidal anti-inflammatory drugs.
10  selective-cyclooxygenase-2
(3 times)
Histocytochemistry
(2 times)
TNBS (2 times)
5-LOX (1 time)
CD (1 time)
2009 Effect of COX-2 inhibitor after TNBS-induced colitis in Wistar rats.
11  consequence of elevated cyclooxygenase-2
(2 times)
Pharmacology
(1 time)
--- 1999 Nimesulide and renal impairment.
12  coxibs, selective inhibitors of cyclooxygenase-2
(2 times)
Brain
(1 time)
--- 2010 Mechanism of K(v)2.1 channel inhibition by a selective COX-2 inhibitor SC-791-modification of gating.
13  cyclooxygenase active site of mouse prostaglandin endoperoxide synthase-2
(2 times)
Biomedical Engineering
(1 time)
COX (1 time)
1999 The binding of arachidonic acid in the cyclooxygenase active site of mouse prostaglandin endoperoxide synthase-2 (COX-2). A putative L-shaped binding conformation utilizing the top channel region.
14  cyclooxygenase or prostaglandin endoperoxide synthase
(2 times)
Cell Death
(1 time)
NF-kappaB (1 time)
TCR (1 time)
2004 In situ analysis of interleukin-1-induced transcription of cox-2 and il-8 in cultured human myometrial cells.
15  cyclooxygenase-2 specific inhibitors
(2 times)
Rheumatology
(1 time)
PPI (2 times)
C/E (1 time)
EGFR (1 time)
2005 Cost-effectiveness analysis of NSAIDs, NSAIDs with concomitant therapy to prevent gastrointestinal toxicity, and COX-2 specific inhibitors in the treatment of rheumatoid arthritis.
16  cyclooxygenase-2-specific
(2 times)
Medicine
(1 time)
CI (1 time)
CKD (1 time)
eGFR (1 time)
2004 Prescription of nonsteroidal anti-inflammatory drugs and muscle relaxants for back pain in the United States.
17  3-methyl-1-phenylchromeno(4,3-c)pyrazol-4(1H)-ones as potential cyclooxygenase-2
(1 time)
Biochemistry
(1 time)
SI (1 time)
2014 Synthesis, biological evaluation and docking analysis of 3-methyl-1-phenylchromeno[4,3-c]pyrazol-4(1H)-ones as potential cyclooxygenase-2 (COX-2) inhibitors.
18  c oxidase-2
(1 time)
Physiological Phenomena
(1 time)
AMP (1 time)
AMPK (1 time)
ATP (1 time)
2018 Benfotiamine, a Lipid-Soluble Analog of Vitamin B1, Improves the Mitochondrial Biogenesis and Function in Blunt Snout Bream (Megalobrama amblycephala) Fed High-Carbohydrate Diets by Promoting the AMPK/PGC-1beta/NRF-1 Axis.
19  capacity of expressing both cyclooxygenase-2
(1 time)
Neoplasms
(1 time)
IL (1 time)
PMA (1 time)
siRNA (1 time)
2006 Reciprocal regulation of cyclooxygenase-2 and 15-hydroxyprostaglandin dehydrogenase expression in A549 human lung adenocarcinoma cells.
20  carcinomas overexpress cyclooxygenase-2
(1 time)
Molecular Biology
(1 time)
AA (1 time)
CA-Akt (1 time)
DMBA (1 time)
2005 Inhibition of TPA-induced cyclooxygenase-2 (COX-2) expression by apigenin through downregulation of Akt signal transduction in human keratinocytes.
21  celecoxib on expression of cyclooxygenase-2
(1 time)
Medicine
(1 time)
FCM (1 time)
RT-PCR (1 time)
2006 [Effects of nonsteroidal anti-inflammatory drug celecoxib on expression of cyclooxygenase-2 (COX-2) in ovarian carcinoma cell].
22  cells overexpressing cyclooxygenase-2
(1 time)
Molecular Biology
(1 time)
HuR (1 time)
HuR-CP1 (1 time)
IR (1 time)
2017 Repression of caspase-3 and RNA-binding protein HuR cleavage by cyclooxygenase-2 promotes drug resistance in oral squamous cell carcinoma.
23  changes of beta-catenin and cyclooxygenase-2
(1 time)
Neoplasms
(1 time)
AOM (1 time)
PA (1 time)
2013 Suppression of beta-catenin and cyclooxygenase-2 expression and cell proliferation in azoxymethane-induced colonic cancer in rats by rice bran phytic acid (PA).
24  CO on the cyclooxygenase-2
(1 time)
Allergy and Immunology
(1 time)
CO (1 time)
HO (1 time)
LPS (1 time)
2010 Carbon monoxide induces cyclooxygenase-2 expression through MAPKs and PKG in phagocytes.
25  codelivery of cyclooxygenase-2
(1 time)
Biomedical Engineering
(1 time)
--- 2018 Celecoxib-Induced Self-Assembly of Smart Albumin-Doxorubicin Conjugate for Enhanced Cancer Therapy.
26  coexpression of shRNA against cyclooxygenase-2
(1 time)
Neoplasms
(1 time)
pol (1 time)
shRNA (1 time)
TRAIL (1 time)
2010 Potent antitumor activity in experimental hepatocellular carcinoma by adenovirus-mediated coexpression of TRAIL and shRNA against COX-2.
27  combination of potent in vitro cyclooxygenase-2
(1 time)
Biochemistry
(1 time)
5-LOX (1 time)
AI (1 time)
2010 Phenylacetic acid regioisomers possessing a N-difluoromethyl-1,2-dihydropyrid-2-one pharmacophore: evaluation as dual inhibitors of cyclooxygenases and 5-lipoxygenase with anti-inflammatory activity.
28  commonly named coxibs
(1 time)
Drug Therapy
(1 time)
--- 2008 Cardiovascular effects of valdecoxib: transducing human pharmacology results into clinical read-outs.
29  comparisons of cyclooxygenase 2
(1 time)
Neoplasms
(1 time)
CAB (1 time)
HF (1 time)
2008 A new prostate cancer therapeutic approach: combination of androgen ablation with COX-2 inhibitor.
30  consequence of upregulation of cyclooxygenase-2
(1 time)
Biochemistry
(1 time)
PPARgamma (1 time)
2011 15-Deoxy-Delta,⁴-prostaglandin J₂, an electrophilic lipid mediator of anti-inflammatory and pro-resolving signaling.
31  consisting of cyclooxygenase isoform-2
(1 time)
Biochemistry
(1 time)
PGE2 (1 time)
2014 Prostaglandin E2 produced by inducible COX-2 and mPGES-1 promoting cancer cell proliferation in vitro and in vivo.
32  coupling of inducible enzymes, cyclooxygenase-2
(1 time)
Biophysics
(1 time)
IL-1beta (1 time)
mPGES-1 (1 time)
PG (1 time)
2006 Effect of peroxisome proliferator activated receptor (PPAR)gamma agonists on prostaglandins cascade in joint cells.
33  COX type-2
(1 time)
Drug Therapy
(1 time)
AD (1 time)
COX-1 (1 time)
1998 The potential application of cyclo-oxygenase type 2 inhibitors to Alzheimer's disease.
34  COX-2 and iNOS
(1 time)
Gastroenterology
(1 time)
GMBF (1 time)
iNOS (1 time)
RT-PCR (1 time)
2004 Cyclooxygenase 2, pS2, inducible nitric oxide synthase and transforming growth factor alpha in gastric adaptation to stress.
35  COX-2 and PGE2 exhibited near-normal levels (p > 0.05) at LASER 3
(1 time)
Biotechnology
(1 time)
LLLT (1 time)
2015 Low-level laser therapy in IL-1beta, COX-2, and PGE2 modulation in partially injured Achilles tendon.
36  COX-2 and VEGF expression scores and survival
(1 time)
Liver Diseases
(1 time)
CH (1 time)
HCC (1 time)
HG-HCC (1 time)
2012 Cyclooxygenase-2 and vascular endothelial growth factor in chronic hepatitis, cirrhosis and hepatocellular carcinoma.
37  COX-2 inhibitor 2
(1 time)
Biomedical Engineering
(1 time)
5-LOX (1 time)
COX-1 (1 time)
IVD (1 time)
2010 Novel insights into the mechanism of decreased expression of type X collagen in human mesenchymal stem cells from patients with osteoarthritis cultured on nitrogen-rich plasma polymers: implication of cyclooxygenase-1.
38  COX-2 selective nonsteroidal anti-inflammatory drug
(1 time)
Gastroenterology
(1 time)
--- 2009 A prospective, randomized, comparative trial of a COX-2 selective nonsteroidal anti-inflammatory drug versus placebo in inguinal herniorrhaphy patients.
39  COX-2, NFkappaB and TNF-alpha levels at day 1 significantly decreased
(1 time)
Gastroenterology
(1 time)
CAT (1 time)
EGCG (1 time)
GSH-Px (1 time)
2014 Beneficial effects of green tea catechin on massive hepatectomy model in rats.
40  COX-2-selective inhibitors
(1 time)
Rheumatology
(1 time)
NICE (1 time)
NSAIDs (1 time)
nsNSAIDs (1 time)
2005 A regional audit of the use of COX-2 selective non-steroidal anti-inflammatory drugs (NSAIDs) in rheumatology clinics in the West Midlands, in relation to NICE guidelines.
41  COX-2/5-LOX inhibitory activities in vitro, and 15e showed optimal inhibitory activities
(1 time)
Biochemistry
(1 time)
--- 2014 Discovery of potential anti-inflammatory drugs: diaryl-1,2,4-triazoles bearing N-hydroxyurea moiety as dual inhibitors of cyclooxygenase-2 and 5-lipoxygenase.
42  COX2.8473
(1 time)
Hematology
(1 time)
CAD (1 time)
2008 Common polymorphisms of cyclooxygenase-2 and prostaglandin E2 receptor and increased risk for acute coronary syndrome in coronary artery disease.
43  coxib based cyclooxygenase-2
(1 time)
Neoplasms
(1 time)
DMC (1 time)
ERS (1 time)
PDT (1 time)
2011 Enhancement of photodynamic therapy by 2,5-dimethyl celecoxib, a non-cyclooxygenase-2 inhibitor analog of celecoxib.
44  cyclo-oxygenase-2 activity
(1 time)
Medicine
(1 time)
AIA (1 time)
ED (1 time)
NOS (1 time)
2016 Endothelial Dysfunction in Rheumatoid Arthritis: Mechanistic Insights and Correlation with Circulating Markers of Systemic Inflammation.
45  cyclooxigenase type 2 inhibitor
(1 time)
Nuclear Medicine
(1 time)
--- 2008 [Demonstration of angiogenesis and the effect on an antiangiogenetic therapy with 99mTc labeled erythrocytes].
46  cyclooxy-2
(1 time)
Molecular Biology
(1 time)
IkappaB (1 time)
LPS (1 time)
NF (1 time)
2004 gamma-Mangostin inhibits inhibitor-kappaB kinase activity and decreases lipopolysaccharide-induced cyclooxygenase-2 gene expression in C6 rat glioma cells.
47  cyclooxygenase 2 homologue
(1 time)
Biology
(1 time)
--- 2005 Biological activity of sea bass (Dicentrarchus labrax L.) recombinant interleukin-1beta.
48  cyclooxygenase 2 mRNA
(1 time)
Neurology
(1 time)
IL-1beta (1 time)
ROS (1 time)
2006 Immobilization stress induces cell death through production of reactive oxygen species in the mouse cerebral cortex.
49  cyclooxygenase-2 selective
(1 time)
Internal Medicine
(1 time)
COX-2s (1 time)
NSAIDs (1 time)
PCPs (1 time)
2006 Over and under-utilization of cyclooxygenase-2 selective inhibitors by primary care physicians and specialists: the tortoise and the hare revisited.
50  cyclooxygenase-2/prostanoid pathway
(1 time)
Environmental Health
(1 time)
CXB (1 time)
2018 Celecoxib, a cyclooxygenase-2 inhibitor, offers chemoprevention against reproductive and neurobehavioural abnormalities induced by atrazine in male Wistar rats.
51  cyclooxygenases was evaluated indirectly by the determination of prostaglandin E2
(1 time)
Pharmacology
(1 time)
AUC (1 time)
2006 Pharmacodynamics, chiral pharmacokinetics, and pharmacokinetic-pharmacodynamic modeling of fenoprofen in patients with diabetes mellitus.
52  cytokines, or expression of cyclooxygenase-2
(1 time)
Allergy and Immunology
(1 time)
EPA (1 time)
iNOS (1 time)
MUFA (1 time)
2015 Incorporation of eicosatrienoic acid exerts mild anti-inflammatory properties in murine RAW264.7 cells.
53  markers-Cycloxygenase-2
(1 time)
Biomedical Engineering
(1 time)
IL-6 (1 time)
2018 Repositing honey incorporated electrospun nanofiber membranes to provide anti-oxidant, anti-bacterial and anti-inflammatory microenvironment for wound regeneration.
54  procumbentin--cyclooxygenase-2
(1 time)
Complementary Therapies
(1 time)
5-LOX (1 time)
COX-1 (1 time)
i.p (1 time)
2009 Antiinflammatory and antinociceptive activities of gossypin and procumbentin--cyclooxygenase-2 (COX-2) inhibition studies.
55  synthase-cyclooxygenase-2
(1 time)
Ophthalmology
(1 time)
CHX (1 time)
PAF (1 time)
1997 Platelet-activating factor induces cyclooxygenase-2 gene expression in corneal epithelium. Requirement of calcium in the signal transduction pathway.