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Abbreviation: CYP17
Appearance Frequency: 211 time(s)
Long forms: 24

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Long Form No. Long Form Research Area Co-occurring Abbreviation PubMed/MEDLINE Info. (Year, Title)
cytochrome P450c17
(112 times)
Endocrinology
(26 times)
AR (7 times)
BMI (4 times)
CI (4 times)
1990 Combined 17 alpha-hydroxylase/17,20-lyase deficiency due to a 7-basepair duplication in the N-terminal region of the cytochrome P45017 alpha (CYP17) gene.
cytochrome P450 17alpha-hydroxylase/17,20-lyase
(62 times)
Endocrinology
(14 times)
PCOS (6 times)
3beta-HSD (4 times)
DHEA (4 times)
1996 Expression of the gene for cytochrome P-450 17 alpha-hydroxylase/C17-20 lyase (CYP17) in porcine Leydig cells: identification of a DNA sequence that mediates cAMP response.
17alpha-hydroxylase-C17,20-lyase
(7 times)
Biochemistry
(6 times)
AR (2 times)
PC (2 times)
CBMI (1 time)
2007 Synthesis and evaluation of novel 17-indazole androstene derivatives designed as CYP17 inhibitors.
cytochrome P450 subfamily 17
(6 times)
Obstetrics
(2 times)
OR (3 times)
CI (2 times)
CYP19 (2 times)
2010 Polymorphisms in catechol-O-methyltransferase and cytochrome p450 subfamily 19 genes predispose towards Madurella mycetomatis-induced mycetoma susceptibility.
cytochrome P450, family 17, subfamily A, polypeptide 1
(3 times)
Neoplasms
(2 times)
AR (2 times)
mCRPC (2 times)
AA (1 time)
2012 Abiraterone in prostate cancer: a new angle to an old problem.
C17-20 lyase P-450
(2 times)
Biochemistry
(2 times)
bp (1 time)
CAT (1 time)
CII (1 time)
1992 Cyclic AMP regulates expression of the rat gene for steroid 17 alpha-hydroxylase/C17-20 lyase P-450 (CYP17) in rat Leydig cells.
CYP17 gene
(2 times)
Neoplasms
(1 time)
BPH (1 time)
CI (1 time)
OR (1 time)
2000 Increased risk of prostate cancer and benign prostatic hyperplasia associated with a CYP17 gene polymorphism with a gene dosage effect.
c-fos expression inhibits 17alpha-hydroxylase 17,20 lyase
(1 time)
Endocrinology
(1 time)
PCOS (1 time)
TPA (1 time)
2007 The mechanism for protein kinase C inhibition of androgen production and 17alpha-hydroxylase expression in a theca cell tumor model.
c-fos functions to inhibit the production of 17alpha-hydroxylase 17,20 lyase
(1 time)
Endocrinology
(1 time)
AP-1 (1 time)
2009 Molecular mechanism for repression of 17alpha-hydroxylase expression and androstenedione production in granulosa cells.
10  cancer risk and polymorphism in 17 hydroxylase
(1 time)
Neoplasms
(1 time)
CI (1 time)
OR (1 time)
SRD5A2 (1 time)
1999 Prostate cancer risk and polymorphism in 17 hydroxylase (CYP17) and steroid reductase (SRD5A2).
11  case of familial 17alpha-hydroxylase/17,20 lyase
(1 time)
Endocrinology
(1 time)
--- 2002 17-Hydroxylase/17,20 lyase deficiency diagnosed during childhood.
12  caused by genetic defects in the gene encoding P450c17
(1 time)
Biochemistry
(1 time)
--- 1995 17 alpha-Hydroxylase/17,20-lyase defects.
13  caused by mutations of the 17alpha-hydroxylase
(1 time)
Genetics, Medical
(1 time)
RFLP (1 time)
1998 Identification of a novel splicing mutation and 1-bp deletion in the 17alpha-hydroxylase gene of Japanese patients with 17alpha-hydroxylase deficiency.
14  cell, is principally at the level of P450c17
(1 time)
Endocrinology
(1 time)
HSD3B2 (1 time)
StAR (1 time)
2008 Androgen synthesis in adrenarche.
15  chemoprevention of prostatic carcinoma have been considered, whereas the 17alpha-hydroxylase/17,20-lyase
(1 time)
Biochemistry
(1 time)
--- 2013 Steroidal 5alpha-reductase and 17alpha-hydroxylase/17,20-lyase (CYP17) inhibitors useful in the treatment of prostatic diseases.
16  cloned and examined the expression of 17alpha-hydroxylase/17,20 lyase
(1 time)
Neurology
(1 time)
--- 2003 Cloning of the zebra finch androgen synthetic enzyme CYP17: a study of its neural expression throughout posthatch development.
17  compound 3beta-hydroxy-17-(1H-benzimidazole-1-yl)androsta-5,16-diene (VN/124-1) is a potent 17alpha-hydroxylase/17,20-lyase
(1 time)
Antineoplastic Agents
(1 time)
AR (1 time)
2008 Androgen receptor inactivation contributes to antitumor efficacy of 17{alpha}-hydroxylase/17,20-lyase inhibitor 3beta-hydroxy-17-(1H-benzimidazole-1-yl)androsta-5,16-diene in prostate cancer.
18  conversion of cholesterol to pregnenolone, 17alpha-hydroxylase/17,20-lyase
(1 time)
Endocrinology
(1 time)
3beta-HSD (1 time)
DHEA (1 time)
DHEAS (1 time)
1998 Adrenarche results from development of a 3beta-hydroxysteroid dehydrogenase-deficient adrenal reticularis.
19  CYP gene family, P450c17
(1 time)
Biochemistry
(1 time)
BS (1 time)
CYP2C11 (1 time)
PR (1 time)
2001 Microsomal p450s use specific proline-rich sequences for efficient folding, but not for maintenance of the folded structure.
20  CYP proteins: 17alpha-hydroxylase-C17/20-lyase
(1 time)
Pharmaceutical Preparations
(1 time)
CYP's (1 time)
2015 Novel functionalized 5-(phenoxymethyl)-1,3-dioxane analogs exhibiting cytochrome P450 inhibition: a patent evaluation WO2015048311 (A1).
21  Cytochrome b(5) modulation of 17(alpha) hydroxylase and 17-20 lyase
(1 time)
Endocrinology
(1 time)
--- 2005 Cytochrome b(5) modulation of 17{alpha} hydroxylase and 17-20 lyase (CYP17) activities in steroidogenesis.
22  cytochrome P17
(1 time)
Neoplasms
(1 time)
CRPC (1 time)
2010 Efficacy of abiraterone acetate in post-docetaxel castration-resistant prostate cancer.
23  Cytochrome P450-C17 enzyme
(1 time)
Molecular Biology
(1 time)
PCOS (1 time)
SNPs (1 time)
2012 Association study of CYP17 and HSD11B1 in polycystic ovary syndrome utilizing comprehensive gene coverage.
24  cytochromes P-450(17alpha,lyase)
(1 time)
Biochemistry
(1 time)
--- 1997 Direct inhibitions of the activities of steroidogenic cytochrome P-450 mono-oxygenase systems by anticonvulsants.