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Abbreviation: DHFR
Appearance Frequency: 2376 time(s)
Long forms: 15

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Long Form No. Long Form Research Area Co-occurring Abbreviation PubMed/MEDLINE Info. (Year, Title)
dihydrofolate reductase
(2340 times)
(542 times)
MTX (366 times)
DHPS (169 times)
TS (146 times)
1973 Studies concerned with overcoming resistance to methotrexate: a comparison of the effects of methotrexate and 2,4-diamino-5-(3',4'-dichlorophenyl)-6-methylpyrimidine (BW50197) on the colony forming ability of L5178Y cells.
dihydrofolic acid reductase
(7 times)
Molecular Biology
(2 times)
MTX (4 times)
2-AF (1 time)
CHO (1 time)
1982 Variable content of double minute chromosomes is not correlated with degree of phenotype instability in methotrexate-resistant human cell lines.
dihydrofolate reductase-encoding gene
(5 times)
Molecular Biology
(5 times)
CHO (2 times)
MTX (2 times)
CFU-GM (1 time)
1990 Use of a selectable reporter for the isolation of mammalian regulatory genes.
(4 times)
(1 time)
HSR (1 time)
kb (1 time)
MTX (1 time)
1987 Novel submicroscopic extrachromosomal elements containing amplified genes in human cells.
dihydrofolate reductase thymidylate synthase
(4 times)
(2 times)
PO (1 time)
PS (1 time)
1998 Plasmodium falciparum: effect of chemical structure on efficacy and specificity of antisense oligonucleotides against malaria in vitro.
developed for human dihydrofolate reductase
(3 times)
(1 time)
PCR (1 time)
QSAR (1 time)
TS (1 time)
1986 pH-Stat titration method for dihydrofolate reductase activity measurements: application to determination of substrate Michaelis constant and antifolate inhibition constant.
drug-resistant forms of dihydrofolate reductase
(3 times)
(1 time)
CML (2 times)
MTX (1 time)
NBMPR-P (1 time)
1990 Invariant amino acid replacement affects the dihydrofolate reductase function and its gene expression.
determined for the dihydrofolate reductase
(2 times)
Anti-Bacterial Agents
(1 time)
--- 1991 Temporal and topological clustering of diverged residues among enterobacterial dihydrofolate reductases.
dihydrofolate reductase inhibitors
(2 times)
(1 time)
AChE (2 times)
ACE (1 time)
BZR (1 time)
2013 Quantum mechanics-based properties for 3D-QSAR.
10  Danish Heart Failure Registry
(1 time)
(1 time)
HF (1 time)
2016 The Danish Heart Failure Registry.
11  degraded FAT10-dihydrofolate reductase
(1 time)
(1 time)
--- 2009 Degradation of FAT10 by the 26S proteasome is independent of ubiquitylation but relies on NUB1L.
12  development has been dihydrofolate reductase
(1 time)
(1 time)
MTX (1 time)
1987 Design and rationale for novel antifolates.
13  dihydrofolate reductase coding sequence
(1 time)
(1 time)
GUS (1 time)
hpt (1 time)
mas (1 time)
1991 Transgenic rice cell lines and plants: expression of transferred chimeric genes.
14  dual targeting ofdihydrofolate reductase
(1 time)
Mtb (1 time)
PAS (1 time)
2019 Drugging the Folate Pathway in Mycobacterium tuberculosis: The Role of Multi-targeting Agents.
15  preSu9(1-112)-dihydrofolate reductase
(1 time)
(1 time)
--- 1999 N-terminal tail export from the mitochondrial matrix. Adherence to the prokaryotic "positive-inside" rule of membrane protein topology.