1 |
epidermal growth factor receptor
(23595 times)
|
Neoplasms (9565 times)
|
NSCLC (4115 times) TKIs (1379 times) PFS (1087 times)
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1983 Mapping of the human gene for epidermal growth factor receptor (EGFR) on the p13 leads to q22 region of chromosome 7.
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2 |
EGF receptor
(1674 times)
|
Neoplasms (398 times)
|
EGF (851 times) TGF-alpha (94 times) NSCLC (68 times)
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1980 Genetic analysis of epidermal growth factor action: assignment of human epidermal growth factor receptor gene to chromosome 7.
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3 |
anti-EGF receptor
(27 times)
|
Neoplasms (15 times)
|
EGF (10 times) mCRC (3 times) NSCLC (3 times)
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1994 [Growth control of a human glioma cell line by multiple autocrine loop blockade].
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4 |
EGFRvIII
(27 times)
|
Neoplasms (16 times)
|
GBM (6 times) mAbs (2 times) NSCLC (2 times)
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1997 Epidermal growth factor receptor stimulation of diacylglycerol kinase.
|
5 |
EGF and its receptor
(15 times)
|
Biology (2 times)
|
EGF (15 times) CNS (1 time) CNT (1 time)
|
1994 Modulation of epidermal growth factor binding and receptor gene expression by hormones and growth factors in sheep pituitary cells.
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6 |
EGFRwt
(6 times)
|
Neoplasms (6 times)
|
GBM (3 times) EGFRvIII (2 times) OS (2 times)
|
2003 Prognostic value of epidermal growth factor receptor in patients with glioblastoma multiforme.
|
7 |
anti-EGFR Affibody molecule, Ac-Cys-Z
(4 times)
|
Neoplasms (1 time)
|
hEGF (1 time) HNSCC (1 time) p.i (1 time)
|
2009 Imaging of EGFR expression in murine xenografts using site-specifically labelled anti-EGFR 111In-DOTA-Z EGFR:2377 Affibody molecule: aspect of the injected tracer amount.
|
8 |
early growth factor receptor
(3 times)
|
Neoplasms (1 time)
|
GNP (1 time) GNPs (1 time)
|
2015 Amphiregulin Is a Critical Downstream Effector of Estrogen Signaling in ERalpha-Positive Breast Cancer.
|
9 |
Economic AnalysisEpidermal Growth Factor Receptor Mutation
(3 times)
|
Biomedical Technology (3 times)
|
CCO (3 times) MAS (3 times) PEPP (3 times)
|
2010 Gene expression profiling for guiding adjuvant chemotherapy decisions in women with early breast cancer: an evidence-based and economic analysis.
|
10 |
epidermal GFR
(3 times)
|
Metabolism (1 time)
|
GFRs (2 times) DCN (1 time) ECM (1 time)
|
2011 Mast cell tryptase stimulates production of decorin by human testicular peritubular cells: possible role of decorin in male infertility by interfering with growth factor signaling.
|
11 |
epidermal growth receptor factor
(3 times)
|
Respiratory Tract Diseases (1 time)
|
AC (1 time) NSCLC (1 time) PET (1 time)
|
1995 [Proliferation behavior of cholesteatoma].
|
12 |
erlotinib, gefitinib
(3 times)
|
Neoplasms (2 times)
|
NSCLC (3 times)
|
2008 Targeted therapy for the treatment of non-small cell lung cancer: focus on inhibition of epidermal growth factor receptor.
|
13 |
EGF and TGF alpha action on their common receptor
(2 times)
|
Gastroenterology (1 time)
|
EGF (1 time) HP (1 time) NO (1 time)
|
1992 Adaptation of gastric mucosa to chronic alcohol administration is associated with increased mucosal expression of growth factors and their receptor.
|
14 |
EGF receptor gene
(2 times)
|
Neoplasms (1 time)
|
AA (1 time) CM (1 time) GBM (1 time)
|
2013 Construction of an immunotoxin, D2C7-(scdsFv)-PE38KDEL, targeting EGFRwt and EGFRvIII for brain tumor therapy.
|
15 |
EGF to its cell surface receptor
(2 times)
|
Neoplasms (2 times)
|
EGF (2 times) AP-1 (1 time) HNSCC (1 time)
|
2008 Fucoidan from Laminaria cichorioides inhibits AP-1 transactivation and cell transformation in the mouse epidermal JB6 cells.
|
16 |
EGFR-eGFP
(2 times)
|
Neoplasms (1 time)
|
EGF (1 time) ERK (1 time) GBM (1 time)
|
2004 Expression of cytoplasmic-domain substituted epidermal growth factor receptor inhibits tumorigenicity of EGFR-overexpressed human glioblastoma multiforme.
|
17 |
EGFR-siRNA
(2 times)
|
Gastroenterology (1 time)
|
BE (1 time) CDX2 (1 time) EGF (1 time)
|
2012 The role of nitric oxide in the induction of caudal-type homeobox 2 through epidermal growth factor receptor in the development of Barrett's esophagus.
|
18 |
EGFR-TKIs
(2 times)
|
Neoplasms (1 time)
|
NSCLC (2 times) mOS (1 time) mPFS (1 time)
|
2015 Experience with erlotinib in the treatment of non-small cell lung cancer.
|
19 |
enhanced growth factor receptor
(2 times)
|
Cell Biology (1 time)
|
CDDS (1 time) GPCR (1 time) MSNs (1 time)
|
2006 Estrogen transactivates EGFR via the sphingosine 1-phosphate receptor Edg-3: the role of sphingosine kinase-1.
|
20 |
epidermal GF receptor
(2 times)
|
Neurosurgery (1 time)
|
GF (2 times) CL (1 time) DCN (1 time)
|
1999 Inhibition of phospholipase C-gamma1 activation blocks glioma cell motility and invasion of fetal rat brain aggregates.
|
21 |
Epidermal growth factor inhibitors
(2 times)
|
Neoplasms (1 time)
|
HNSCC (1 time)
|
2006 [Treatment of acneiform rash by epidermal growth factor inhibitors with oral tetracyclines].
|
22 |
epidermal receptor growth factor
(2 times)
|
Neoplasms (1 time)
|
BCSS (1 time) FISH (1 time) IHC (1 time)
|
2010 Epidermal growth factor receptor and vascular endothelial growth factor receptor 2 are specific biomarkers in triple-negative breast cancer. Results from a controlled randomized trial with long-term follow-up.
|
23 |
HB-EGF, and EGF receptor
(2 times)
|
Nephrology (1 time)
|
HB-EGF (2 times) COPD (1 time) NF-kappaB (1 time)
|
2012 Epidermal growth factor: a new therapeutic target in glomerular disease.
|
24 |
HB-EGF-induced EGF receptor
(2 times)
|
Neurology (1 time)
|
HB-EGF (2 times) ADAM17 (1 time) CsA (1 time)
|
2011 Cyclosporin A and tacrolimus induce renal Erk1/2 pathway via ROS-induced and metalloproteinase-dependent EGF-receptor signaling.
|
25 |
alpha6beta4-EGF receptor
(1 time)
|
Reproductive Medicine (1 time)
|
AR (1 time) EGF (1 time)
|
2003 Androgen receptor and prostate cancer invasion.
|
26 |
anti-EGFR Ac-Cys-Z
(1 time)
|
Nuclear Medicine (1 time)
|
---
|
2012 PET of EGFR expression with an 18F-labeled affibody molecule.
|
27 |
anti-endothelial growth factor
(1 time)
|
Gastroenterology (1 time)
|
5-FU (1 time) mCRC (1 time) NCCN (1 time)
|
2011 Treatment decisions after diagnosis of metastatic colorectal cancer.
|
28 |
EGF are mediated through the receptor
(1 time)
|
Biochemistry (1 time)
|
---
|
2011 MAPK scaffold IQGAP1 binds the EGF receptor and modulates its activation.
|
29 |
EGF binds to specific receptors
(1 time)
|
Cell Biology (1 time)
|
---
|
2015 Unconventional EGF-induced ERK1/2-mediated Kv1.3 endocytosis.
|
30 |
EGF family member
(1 time)
|
Genes, Neoplasm (1 time)
|
Ad (1 time)
|
2011 Expression of the Adenovirus Early Gene 1A Transcription-Repression Domain Alone Downregulates HER2 and Results in the Death of Human Breast Cancer Cells Upregulated for the HER2 Proto-Oncogene.
|
31 |
EGF from EGF receptor
(1 time)
|
Complementary Therapies (1 time)
|
BPH (1 time) EGF (1 time) GM-CSF (1 time)
|
2011 Androgen-independent effects of Serenoa repens extract (Prostasan) on prostatic epithelial cell proliferation and inflammation.
|
32 |
EGF, TGF alpha and their receptor
(1 time)
|
Gynecology (1 time)
|
3beta-HSD (1 time) SCC (1 time)
|
1995 [Human folliculogenesis and local regulation].
|
33 |
EGF/TGF-alpha receptor
(1 time)
|
Molecular Biology (1 time)
|
wa-1 (1 time) wa-2 (1 time)
|
1994 The mouse waved-2 phenotype results from a point mutation in the EGF receptor tyrosine kinase.
|
34 |
EGF/TGF-alpha tyrosine kinase receptor
(1 time)
|
Cell Biology (1 time)
|
Cip1 (1 time) TGF-alpha (1 time)
|
2000 The tetraspanin CD9 associates with transmembrane TGF-alpha and regulates TGF-alpha-induced EGF receptor activation and cell proliferation.
|
35 |
EGFR amplification
(1 time)
|
General Surgery (1 time)
|
GBM (1 time) TMZ (1 time)
|
2012 Paradoxical relationship between the degree of EGFR amplification and outcome in glioblastomas.
|
36 |
EGFR antibodies
(1 time)
|
Neoplasms (1 time)
|
BUN (1 time) LP (1 time) NSCLC (1 time)
|
2014 A cisplatin‑incorporated liposome that targets the epidermal growth factor receptor enhances radiotherapeutic efficacy without nephrotoxicity.
|
37 |
EGFR gene
(1 time)
|
General Surgery (1 time)
|
EGFR-TKIs (1 time) NSCLC (1 time) p-EGFR (1 time)
|
2011 The influence of intracellular epidermal growth factor receptor (EGFR) signal activation on the outcome of EGFR tyrosine kinase inhibitor treatment for pulmonary adenocarcinoma.
|
38 |
EGFR inhibitor
(1 time)
|
Biochemistry (1 time)
|
COX (1 time) E2-BSA-FITC (1 time) OECs (1 time)
|
2015 Regulation of cyclooxygenase-2 expression in rat oviductal epithelial cells: Evidence for involvement of GPR30/Src kinase-mediated EGFR signaling.
|
39 |
EGFR pathway, including erlotinib
(1 time)
|
|
CDX (1 time) Erl-SiTMR-T (1 time) HNSCC (1 time)
|
2020 Intracellular paired agent imaging enables improved evaluation of tyrosine kinase inhibitor target engagement.
|
40 |
EGFR pharmDX kit
(1 time)
|
Science (1 time)
|
ATC (1 time) PDTC (1 time)
|
2005 Epidermal growth factor receptor as a novel therapeutic target in anaplastic thyroid carcinomas.
|
41 |
EGFR tyrosine kinase inhibitor
(1 time)
|
Chemistry Techniques, Analytical (1 time)
|
---
|
2019 Determination of BPI15086 and its metabolite in human plasma by ultra-high performance liquid chromatography-MS/MS and its application to a pharmacokinetic study.
|
42 |
EGFR, as pan-Erb
(1 time)
|
Vascular Diseases (1 time)
|
KSR1 (1 time) TF (1 time)
|
2010 Modulation of the oncogene-dependent tissue factor expression by kinase suppressor of ras 1.
|
43 |
EGFR-mAbs
(1 time)
|
Neoplasms (1 time)
|
BTC (1 time) CHT (1 time) PFS (1 time)
|
2020 Anti-EGFR Monoclonal Antibodies in Advanced Biliary Tract Cancer: A Systematic Review and Meta-analysis.
|
44 |
EGFR-targeting protein, the DOTA-Z
(1 time)
|
Nuclear Medicine (1 time)
|
---
|
2009 Imaging of EGFR expression in murine xenografts using site-specifically labelled anti-EGFR 111In-DOTA-Z EGFR:2377 Affibody molecule: aspect of the injected tracer amount.
|
45 |
EGFRlow
(1 time)
|
Neoplasms (1 time)
|
PC (1 time) TKI (1 time)
|
2011 Epidermal Growth Factor Receptor (EGFR) mutation analysis, gene expression profiling and EGFR protein expression in primary prostate cancer.
|
46 |
EGFRmut
(1 time)
|
General Surgery (1 time)
|
IHC (1 time) OS (1 time) RFS (1 time)
|
2016 Clinical Significance of C-MET Overexpression and Epidermal Growth Factor Receptor Mutation in Platinum-Based Adjuvant Chemotherapy Outcome in Surgically Resected Lung Adenocarcinoma.
|
47 |
elegans identified CDT-2 as an attenuator of LET-23
(1 time)
|
Embryology (1 time)
|
---
|
2010 The Caenorhabditis elegans CDT-2 ubiquitin ligase is required for attenuation of EGFR signalling in vulva precursor cells.
|
48 |
elements of the EV/EP cargo, including oncoproteins
(1 time)
|
Nanotechnology (1 time)
|
AFM (1 time) EP (1 time) EV (1 time)
|
2019 Mapping Subpopulations of Cancer Cell-Derived Extracellular Vesicles and Particles by Nano-Flow Cytometry.
|
49 |
encoding the whole isoform a
(1 time)
|
Neoplasms (1 time)
|
Ext-Ab (1 time)
|
2011 Adult diffuse gliomas produce mRNA transcripts encoding EGFR isoforms lacking a tyrosine kinase domain.
|
50 |
endothelial growth factor receptors expression
(1 time)
|
Chemistry (1 time)
|
LNCs (1 time)
|
2013 EGFR siRNA lipid nanocapsules efficiently transfect glioma cells in vitro.
|
51 |
endothelial-GF receptor
(1 time)
|
Male Urogenital Diseases (1 time)
|
CG (1 time) EG (1 time) FG (1 time)
|
2015 The effect of penile urethral fat graft application on urethral angiogenesis.
|
52 |
enrolled CRC patients treated with antiepidermal growth factor receptor
(1 time)
|
Medicine (1 time)
|
CI (1 time) CRC (1 time) HR (1 time)
|
2017 Prognostic value of KRAS codon 13 gene mutation for overall survival in colorectal cancer: Direct and indirect comparison meta-analysis.
|
53 |
epidermal growth factor and its transmembrane receptor
(1 time)
|
Neoplasms (1 time)
|
---
|
2008 Developments in epidermal growth factor receptor-targeting therapy for solid tumors: focus on matuzumab (EMD 72000).
|
54 |
epidermal growth factor of upstream receptor
(1 time)
|
Medicine (1 time)
|
---
|
2011 [Identification of K-RAS mutations in colorectal cancer patients in Israel].
|
55 |
epidermal growth factor tyrosine kinase receptors
(1 time)
|
Biochemistry (1 time)
|
---
|
2002 Interaction between two ubiquitin-protein isopeptide ligases of different classes, CBLC and AIP4/ITCH.
|
56 |
epidermal growth factor urothelial receptor
(1 time)
|
Urology (1 time)
|
EGF (1 time)
|
1994 [Quantitative determination of epidermal growth factor urothelial receptor (EGFR) in superficial and invasive bladder carcinoma].
|
57 |
epidermal growth factor-like repeats
(1 time)
|
Brain (1 time)
|
CADASIL (1 time)
|
2009 Distinct phenotypic and functional features of CADASIL mutations in the Notch3 ligand binding domain.
|
58 |
epithelial changes after using epidermal
(1 time)
|
Ophthalmology (1 time)
|
FGFR (1 time) IRB (1 time)
|
2020 Markedly increased ocular side effect causing severe vision deterioration after chemotherapy using new or investigational epidermal or fibroblast growth factor receptor inhibitors.
|
59 |
ErbB family consists of four proteins including
(1 time)
|
Neoplasms (1 time)
|
CRC (1 time) pEGFR (1 time) pErbB2 (1 time)
|
2014 Localization of phosphorylated ErbB1-4 and heregulin in colorectal cancer.
|
60 |
erlotinib, gefitinib, cetuximab
(1 time)
|
Neoplasms (1 time)
|
NSCLC (1 time) VEGF (1 time)
|
2009 Investigational agents in the management of non-small cell lung cancer.
|
61 |
erlotinib, gefitinib, lapatinib
(1 time)
|
Clinical Trials as Topic (1 time)
|
---
|
2015 Novel targeted therapies in chordoma: an update.
|
62 |
evaluate the gamma-imaging properties of an antiepidermal growth factor receptor
(1 time)
|
Nuclear Medicine (1 time)
|
DTPA (1 time) PEG (1 time) ROIs (1 time)
|
2001 Conjugation with (111)In-DTPA-poly(ethylene glycol) improves imaging of anti-EGF receptor antibody C225.
|
63 |
evaluate the possibility of treatment with antiepidermal growth factor receptor
(1 time)
|
Neoplasms (1 time)
|
ADCC (1 time) SCC (1 time) TGF (1 time)
|
2006 Cetuximab induce antibody-dependent cellular cytotoxicity against EGFR-expressing esophageal squamous cell carcinoma.
|
64 |
evident that growth factor receptors
(1 time)
|
Cell Biology (1 time)
|
CTGF (1 time) ECM (1 time) PAI-1 (1 time)
|
2010 Linking cell structure to gene regulation: signaling events and expression controls on the model genes PAI-1 and CTGF.
|
65 |
expression of growth factor
(1 time)
|
Dentistry (1 time)
|
---
|
2006 Expression of p53, Ki-67, and EGFR in odontogenic keratocysts before and after decompression.
|
66 |
expression of growth factor receptors
(1 time)
|
Neoplasms (1 time)
|
---
|
2000 Immunohistochemical analysis of expression of a 65 kDa oncofetal protein (p65), epidermal growth factor receptor (EGFR), oncogene c-erb B2 and tumor suppressor gene p53 protein products in breast cancer patients.
|
67 |
expression profiles of five parameters as potential mediators in neoangiogenesis
(1 time)
|
Gastroenterology (1 time)
|
---
|
2009 Haemorrhoids are related to changes of cell function in mucosa and submucosa.
|
68 |
Gurken-EGF receptor
(1 time)
|
Embryology (1 time)
|
EGF (1 time)
|
2020 Signaling between somatic follicle cells and the germline patterns the egg and embryo of Drosophila.
|
69 |
HB-EGF processing or EGF receptor
(1 time)
|
Science (1 time)
|
14,15-EET (1 time) HB-EGF (1 time)
|
2002 Heparin-binding EGF-like growth factor mediates the biological effects of P450 arachidonate epoxygenase metabolites in epithelial cells.
|
70 |
include growth factors and their receptors
(1 time)
|
Gynecology (1 time)
|
---
|
2009 [Expression of selected angiogenesis markers and modulators in pre-, peri- and postmenopausal women with ovarian cancer].
|
71 |
measured, glomerular filtration rate
(1 time)
|
Biomedical Research (1 time)
|
CRP (1 time)
|
2020 Effect of Different Hemodialysis Methods on Microbiota in Uremic Patients.
|
72 |
pathways--Epithelial Growth Factor Receptor
(1 time)
|
Neoplasms (1 time)
|
GC (1 time) MAPK (1 time) MSI (1 time)
|
2010 Oncogenic mutations in gastric cancer with microsatellite instability.
|
73 |
phospho-EGF receptor
(1 time)
|
Cell Biology (1 time)
|
EGF (1 time) ROS (1 time)
|
2020 Epiregulin promotes hair growth via EGFR-medicated epidermal and ErbB4-mediated dermal stimulation.
|
74 |
STAT3-EGF receptor
(1 time)
|
Neoplasms (1 time)
|
CCND1 (1 time) HA (1 time) MMP (1 time)
|
2013 A novel inhibitor of STAT3 homodimerization selectively suppresses STAT3 activity and malignant transformation.
|