| 1 |
epidermal growth factor receptor
(20301 times)
|
Neoplasms
(8471 times)
|
NSCLC (3218 times)
TKIs (1050 times)
PFS (822 times)
|
0 [Effect of Erlotinib in 2nd and 3rd Line Anticancer Treatment in Patients with Squamous Cell Lung Cancer - Case Series].
|
| 2 |
EGF receptor
(1608 times)
|
Neoplasms
(391 times)
|
EGF (814 times)
NSCLC (65 times)
TGF-alpha (64 times)
|
1980 Genetic analysis of epidermal growth factor action: assignment of human epidermal growth factor receptor gene to chromosome 7.
|
| 3 |
anti-EGF receptor
(27 times)
|
Neoplasms
(15 times)
|
EGF (10 times)
mCRC (3 times)
NSCLC (3 times)
|
1994 [Growth control of a human glioma cell line by multiple autocrine loop blockade].
|
| 4 |
EGFRvIII
(26 times)
|
Neoplasms
(16 times)
|
GBM (5 times)
mAbs (2 times)
NSCLC (2 times)
|
1997 Epidermal growth factor receptor stimulation of diacylglycerol kinase.
|
| 5 |
EGF and its receptor
(14 times)
|
Neoplasms
(2 times)
|
EGF (14 times)
CNS (1 time)
CNT (1 time)
|
1994 Modulation of epidermal growth factor binding and receptor gene expression by hormones and growth factors in sheep pituitary cells.
|
| 6 |
EGFRwt
(5 times)
|
Neoplasms
(5 times)
|
GBM (2 times)
OS (2 times)
EGFRvIII (1 time)
|
2003 Prognostic value of epidermal growth factor receptor in patients with glioblastoma multiforme.
|
| 7 |
anti-EGFR Affibody molecule, Ac-Cys-Z
(4 times)
|
Radiotherapy
(1 time)
|
hEGF (1 time)
HNSCC (1 time)
p.i (1 time)
|
2010 Imaging of EGFR expression in murine xenografts using site-specifically labelled anti-EGFR 111In-DOTA-Z EGFR:2377 Affibody molecule: aspect of the injected tracer amount.
|
| 8 |
Economic AnalysisEpidermal Growth Factor Receptor Mutation
(3 times)
|
Biomedical Technology
(3 times)
|
CCO (3 times)
MAS (3 times)
PEPP (3 times)
|
2010 Gene expression profiling for guiding adjuvant chemotherapy decisions in women with early breast cancer: an evidence-based and economic analysis.
|
| 9 |
epidermal GFR
(3 times)
|
Metabolism
(1 time)
|
GFRs (2 times)
DCN (1 time)
ECM (1 time)
|
2011 Mast cell tryptase stimulates production of decorin by human testicular peritubular cells: possible role of decorin in male infertility by interfering with growth factor signaling.
|
| 10 |
epidermal growth receptor factor
(3 times)
|
Otolaryngology
(1 time)
|
AC (1 time)
NSCLC (1 time)
PET (1 time)
|
1995 [Proliferation behavior of cholesteatoma].
|
| 11 |
erlotinib, gefitinib
(3 times)
|
Neoplasms
(2 times)
|
NSCLC (3 times)
|
2008 Targeted therapy for the treatment of non-small cell lung cancer: focus on inhibition of epidermal growth factor receptor.
|
| 12 |
EGF and TGF alpha and their common receptor
(2 times)
|
Gastroenterology
(1 time)
|
EGF (1 time)
HP (1 time)
NO (1 time)
|
1992 Adaptation of gastric mucosa to chronic alcohol administration is associated with increased mucosal expression of growth factors and their receptor.
|
| 13 |
EGF receptor gene
(2 times)
|
Neoplasms
(1 time)
|
aa (1 time)
CM (1 time)
GBM (1 time)
|
2013 Construction of an immunotoxin, D2C7-(scdsFv)-PE38KDEL, targeting EGFRwt and EGFRvIII for brain tumor therapy.
|
| 14 |
EGF to its cell surface receptor
(2 times)
|
Neoplasms
(2 times)
|
EGF (2 times)
AP-1 (1 time)
HNSCC (1 time)
|
2008 Fucoidan from Laminaria cichorioides inhibits AP-1 transactivation and cell transformation in the mouse epidermal JB6 cells.
|
| 15 |
EGFR-siRNA
(2 times)
|
Gastroenterology
(1 time)
|
BE (1 time)
CDX2 (1 time)
EGF (1 time)
|
2012 The role of nitric oxide in the induction of caudal-type homeobox 2 through epidermal growth factor receptor in the development of Barrett's esophagus.
|
| 16 |
EGFR-TKIs
(2 times)
|
Neoplasms
(1 time)
|
NSCLC (2 times)
mOS (1 time)
mPFS (1 time)
|
2015 Experience with erlotinib in the treatment of non-small cell lung cancer.
|
| 17 |
EGFRt-EGFP
(2 times)
|
Neoplasms
(1 time)
|
EGF (1 time)
ERK (1 time)
GBM (1 time)
|
2004 Expression of cytoplasmic-domain substituted epidermal growth factor receptor inhibits tumorigenicity of EGFR-overexpressed human glioblastoma multiforme.
|
| 18 |
enhanced growth factor receptor
(2 times)
|
Cell Biology
(1 time)
|
GPCR (1 time)
S1P (1 time)
SphK1 (1 time)
|
2006 Estrogen transactivates EGFR via the sphingosine 1-phosphate receptor Edg-3: the role of sphingosine kinase-1.
|
| 19 |
epidermal GF receptor
(2 times)
|
Neurosurgery
(1 time)
|
GF (2 times)
CL (1 time)
DCN (1 time)
|
1999 Inhibition of phospholipase C-gamma1 activation blocks glioma cell motility and invasion of fetal rat brain aggregates.
|
| 20 |
Epidermal growth factor inhibitors
(2 times)
|
Dermatology
(1 time)
|
HNSCC (1 time)
|
2006 [Treatment of acneiform rash by epidermal growth factor inhibitors with oral tetracyclines].
|
| 21 |
epidermal growth factor mutations
(2 times)
|
Internal Medicine
(1 time)
|
---
|
2017 De novo activating epidermal growth factor mutations (EGFR) in small-cell lung cancer.
|
| 22 |
epidermal receptor growth factor
(2 times)
|
Neoplasms
(1 time)
|
BCSS (1 time)
FISH (1 time)
IHC (1 time)
|
0 [Two perspectives on venous thromboembolism in oncology].
|
| 23 |
HB-EGF-induced EGF receptor
(2 times)
|
Neurology
(1 time)
|
HB-EGF (2 times)
ADAM17 (1 time)
CsA (1 time)
|
2012 Cyclosporin A and tacrolimus induce renal Erk1/2 pathway via ROS-induced and metalloproteinase-dependent EGF-receptor signaling.
|
| 24 |
alpha6beta4-EGF receptor
(1 time)
|
Reproductive Medicine
(1 time)
|
AR (1 time)
EGF (1 time)
|
2003 Androgen receptor and prostate cancer invasion.
|
| 25 |
anti-EGFR Ac-Cys-Z
(1 time)
|
Nuclear Medicine
(1 time)
|
---
|
2012 PET of EGFR expression with an 18F-labeled affibody molecule.
|
| 26 |
anti-endothelial growth factor
(1 time)
|
Gastroenterology
(1 time)
|
5-FU (1 time)
mCRC (1 time)
NCCN (1 time)
|
2012 Treatment decisions after diagnosis of metastatic colorectal cancer.
|
| 27 |
EGF are mediated through the receptor
(1 time)
|
Biochemistry
(1 time)
|
---
|
2011 MAPK scaffold IQGAP1 binds the EGF receptor and modulates its activation.
|
| 28 |
EGF binds to specific receptors
(1 time)
|
Cell Biology
(1 time)
|
---
|
2016 Unconventional EGF-induced ERK1/2-mediated Kv1.3 endocytosis.
|
| 29 |
EGF family member
(1 time)
|
Genes, Neoplasm
(1 time)
|
Ad (1 time)
|
2011 Expression of the Adenovirus Early Gene 1A Transcription-Repression Domain Alone Downregulates HER2 and Results in the Death of Human Breast Cancer Cells Upregulated for the HER2 Proto-Oncogene.
|
| 30 |
EGF from EGF receptor
(1 time)
|
Complementary Therapies
(1 time)
|
BPH (1 time)
EGF (1 time)
GM-CSF (1 time)
|
2012 Androgen-independent effects of Serenoa repens extract (Prostasan) on prostatic epithelial cell proliferation and inflammation.
|
| 31 |
EGF, TGF alpha and their receptor
(1 time)
|
Gynecology
(1 time)
|
3beta-HSD (1 time)
scc (1 time)
|
1995 [Human folliculogenesis and local regulation].
|
| 32 |
EGF/TGF-alpha receptor
(1 time)
|
Molecular Biology
(1 time)
|
wa-1 (1 time)
wa-2 (1 time)
|
1994 The mouse waved-2 phenotype results from a point mutation in the EGF receptor tyrosine kinase.
|
| 33 |
EGF/TGF-alpha tyrosine kinase receptor
(1 time)
|
Cell Biology
(1 time)
|
Cip1 (1 time)
TGF-alpha (1 time)
|
2000 The tetraspanin CD9 associates with transmembrane TGF-alpha and regulates TGF-alpha-induced EGF receptor activation and cell proliferation.
|
| 34 |
EGFR amplification
(1 time)
|
General Surgery
(1 time)
|
GBM (1 time)
TMZ (1 time)
|
2012 Paradoxical relationship between the degree of EGFR amplification and outcome in glioblastomas.
|
| 35 |
EGFR antibodies
(1 time)
|
Neoplasms
(1 time)
|
BUN (1 time)
LP (1 time)
NSCLC (1 time)
|
2015 A cisplatin‑incorporated liposome that targets the epidermal growth factor receptor enhances radiotherapeutic efficacy without nephrotoxicity.
|
| 36 |
EGFR gene
(1 time)
|
General Surgery
(1 time)
|
EGFR-TKIs (1 time)
NSCLC (1 time)
p-EGFR (1 time)
|
2011 The influence of intracellular epidermal growth factor receptor (EGFR) signal activation on the outcome of EGFR tyrosine kinase inhibitor treatment for pulmonary adenocarcinoma.
|
| 37 |
EGFR inhibitor
(1 time)
|
Biochemistry
(1 time)
|
COX (1 time)
E2-BSA-FITC (1 time)
OECs (1 time)
|
2015 Regulation of cyclooxygenase-2 expression in rat oviductal epithelial cells: Evidence for involvement of GPR30/Src kinase-mediated EGFR signaling.
|
| 38 |
EGFR pharmDX kit
(1 time)
|
Science
(1 time)
|
ATC (1 time)
PDTC (1 time)
|
2004 Epidermal growth factor receptor as a novel therapeutic target in anaplastic thyroid carcinomas.
|
| 39 |
EGFR, as pan-Erb
(1 time)
|
Vascular Diseases
(1 time)
|
KSR1 (1 time)
TF (1 time)
|
2010 Modulation of the oncogene-dependent tissue factor expression by kinase suppressor of ras 1.
|
| 40 |
EGFR-targeting protein, the DOTA-Z
(1 time)
|
Nuclear Medicine
(1 time)
|
---
|
2010 Imaging of EGFR expression in murine xenografts using site-specifically labelled anti-EGFR 111In-DOTA-Z EGFR:2377 Affibody molecule: aspect of the injected tracer amount.
|
| 41 |
EGFRlow
(1 time)
|
Neoplasms
(1 time)
|
PC (1 time)
TKI (1 time)
|
2011 Epidermal Growth Factor Receptor (EGFR) mutation analysis, gene expression profiling and EGFR protein expression in primary prostate cancer.
|
| 42 |
EGFRmut
(1 time)
|
General Surgery
(1 time)
|
IHC (1 time)
OS (1 time)
RFS (1 time)
|
2017 Clinical Significance of C-MET Overexpression and Epidermal Growth Factor Receptor Mutation in Platinum-Based Adjuvant Chemotherapy Outcome in Surgically Resected Lung Adenocarcinoma.
|
| 43 |
elegans identified CDT-2 as an attenuator of LET-23
(1 time)
|
Embryology
(1 time)
|
---
|
2010 The Caenorhabditis elegans CDT-2 ubiquitin ligase is required for attenuation of EGFR signalling in vulva precursor cells.
|
| 44 |
encoding the whole isoform a
(1 time)
|
Neoplasms
(1 time)
|
Ext-Ab (1 time)
|
2012 Adult diffuse gliomas produce mRNA transcripts encoding EGFR isoforms lacking a tyrosine kinase domain.
|
| 45 |
endothelial growth factor receptors expression
(1 time)
|
Chemistry
(1 time)
|
LNCs (1 time)
|
2013 EGFR siRNA lipid nanocapsules efficiently transfect glioma cells in vitro.
|
| 46 |
endothelial-GF receptor
(1 time)
|
Male Urogenital Diseases
(1 time)
|
CG (1 time)
EG (1 time)
FG (1 time)
|
2015 The effect of penile urethral fat graft application on urethral angiogenesis.
|
| 47 |
enrolled CRC patients treated with antiepidermal growth factor receptor
(1 time)
|
Medicine
(1 time)
|
CI (1 time)
CRC (1 time)
HR (1 time)
|
2017 Prognostic value of KRAS codon 13 gene mutation for overall survival in colorectal cancer: Direct and indirect comparison meta-analysis.
|
| 48 |
epidermal growth factor and its transmembrane receptor
(1 time)
|
Neoplasms
(1 time)
|
---
|
2008 Developments in epidermal growth factor receptor-targeting therapy for solid tumors: focus on matuzumab (EMD 72000).
|
| 49 |
epidermal growth factor of upstream receptor
(1 time)
|
Medicine
(1 time)
|
---
|
2011 [Identification of K-RAS mutations in colorectal cancer patients in Israel].
|
| 50 |
epidermal growth factor tyrosine kinase receptors
(1 time)
|
Biochemistry
(1 time)
|
---
|
2002 Interaction between two ubiquitin-protein isopeptide ligases of different classes, CBLC and AIP4/ITCH.
|
| 51 |
epidermal growth factor urothelial receptor
(1 time)
|
Urology
(1 time)
|
EGF (1 time)
|
1994 [Quantitative determination of epidermal growth factor urothelial receptor (EGFR) in superficial and invasive bladder carcinoma].
|
| 52 |
epidermal growth factor-like repeats
(1 time)
|
Brain
(1 time)
|
CADASIL (1 time)
|
2009 Distinct phenotypic and functional features of CADASIL mutations in the Notch3 ligand binding domain.
|
| 53 |
epidermal growth factor/TGF alpha receptor
(1 time)
|
Endocrinology
(1 time)
|
PAI-1 (1 time)
TGF alpha (1 time)
TNF-alpha (1 time)
|
1997 Tumor necrosis factor-alpha regulates plasminogen activator inhibitor-1 in rat testicular peritubular cells.
|
| 54 |
ErbB family consists of four proteins including
(1 time)
|
Neoplasms
(1 time)
|
CRC (1 time)
pEGFR (1 time)
pErbB2 (1 time)
|
2014 Localization of phosphorylated ErbB1-4 and heregulin in colorectal cancer.
|
| 55 |
erlotinib, gefitinib, cetuximab
(1 time)
|
Neoplasms
(1 time)
|
NSCLC (1 time)
VEGF (1 time)
|
2009 Investigational agents in the management of non-small cell lung cancer.
|
| 56 |
erlotinib, gefitinib, lapatinib
(1 time)
|
Clinical Trials as Topic
(1 time)
|
---
|
2015 Novel targeted therapies in chordoma: an update.
|
| 57 |
evaluate the gamma-imaging properties of an antiepidermal growth factor receptor
(1 time)
|
Nuclear Medicine
(1 time)
|
DTPA (1 time)
PEG (1 time)
ROIs (1 time)
|
2001 Conjugation with (111)In-DTPA-poly(ethylene glycol) improves imaging of anti-EGF receptor antibody C225.
|
| 58 |
evaluate the possibility of treatment with antiepidermal growth factor receptor
(1 time)
|
Neoplasms
(1 time)
|
ADCC (1 time)
SCC (1 time)
TGF (1 time)
|
2007 Cetuximab induce antibody-dependent cellular cytotoxicity against EGFR-expressing esophageal squamous cell carcinoma.
|
| 59 |
evident that growth factor receptors
(1 time)
|
Cell Biology
(1 time)
|
CTGF (1 time)
ECM (1 time)
PAI-1 (1 time)
|
2010 Linking cell structure to gene regulation: signaling events and expression controls on the model genes PAI-1 and CTGF.
|
| 60 |
expression of growth factor
(1 time)
|
Dentistry
(1 time)
|
---
|
2006 Expression of p53, Ki-67, and EGFR in odontogenic keratocysts before and after decompression.
|
| 61 |
expression of growth factor receptors
(1 time)
|
Neoplasms
(1 time)
|
---
|
2000 Immunohistochemical analysis of expression of a 65 kDa oncofetal protein (p65), epidermal growth factor receptor (EGFR), oncogene c-erb B2 and tumor suppressor gene p53 protein products in breast cancer patients.
|
| 62 |
expression profiles of five parameters as potential mediators in neoangiogenesis
(1 time)
|
Gastroenterology
(1 time)
|
---
|
2009 Haemorrhoids are related to changes of cell function in mucosa and submucosa.
|
| 63 |
HB-EGF processing or EGF receptor
(1 time)
|
Science
(1 time)
|
14,15-EET (1 time)
HB-EGF (1 time)
|
2002 Heparin-binding EGF-like growth factor mediates the biological effects of P450 arachidonate epoxygenase metabolites in epithelial cells.
|
| 64 |
HB-EGF, the EGF receptor
(1 time)
|
Nephrology
(1 time)
|
HB-EGF (1 time)
RPGN (1 time)
|
2012 Epidermal growth factor: a new therapeutic target in glomerular disease.
|
| 65 |
include growth factors and their receptors
(1 time)
|
Gynecology
(1 time)
|
---
|
2009 [Expression of selected angiogenesis markers and modulators in pre-, peri- and postmenopausal women with ovarian cancer].
|
| 66 |
pathways--Epithelial Growth Factor Receptor
(1 time)
|
Neoplasms
(1 time)
|
GC (1 time)
MAPK (1 time)
MSI (1 time)
|
2011 Oncogenic mutations in gastric cancer with microsatellite instability.
|
| 67 |
STAT3-EGF receptor
(1 time)
|
Neoplasms
(1 time)
|
CCND1 (1 time)
HA (1 time)
MMP (1 time)
|
2013 A novel inhibitor of STAT3 homodimerization selectively suppresses STAT3 activity and malignant transformation.
|
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