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Abbreviation: ENaC
Appearance Frequency: 2016 time(s)
Long forms: 61

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Long Form No. Long Form Research Area Co-occurring Abbreviation PubMed/MEDLINE Info. (Year, Title)
epithelial sodium channel
(1934 times)
Physiology
(605 times)
CFTR (128 times)
CF (98 times)
CCD (73 times)
1994 Membrane topology of the amiloride-sensitive epithelial sodium channel.
epithelial amiloride-sensitive sodium channel
(8 times)
Molecular Biology
(3 times)
AGT (1 time)
alphaENaC (1 time)
AMPK (1 time)
1996 Cell surface expression of the epithelial Na channel and a mutant causing Liddle syndrome: a quantitative approach.
expression and activity of the epithelial sodium channel
(8 times)
Nephrology
(3 times)
AT1R (1 time)
BPD (1 time)
CFTR (1 time)
1998 Salt and water transport across the alveolar epithelium in the developing lung: correlations between function and recent molecular biology advances (Review).
enhanced epithelial sodium channel
(4 times)
Endocrinology
(3 times)
CVD (2 times)
ERalpha (2 times)
SGK-1 (2 times)
2010 Hyperaldosteronism in Klotho-deficient mice.
epithelial Na(+)-selective channels
(2 times)
Physiology
(1 time)
CCD (1 time)
CF (1 time)
DCT (1 time)
1996 Cell-specific expression of amiloride-sensitive, Na(+)-conducting ion channels in the kidney.
epithelial sodium channel family
(2 times)
Biochemistry
(1 time)
AM (1 time)
ARDS (1 time)
EtOH (1 time)
1999 Mutational analysis of cysteine-rich domains of the epithelium sodium channel (ENaC). Identification of cysteines essential for channel expression at the cell surface.
excessive Na(+) absorption through the epithelial sodium channel
(2 times)
Biochemistry
(2 times)
CF (2 times)
ASL (1 time)
CFTR (1 time)
2006 Airway surface liquid volume regulates ENaC by altering the serine protease-protease inhibitor balance: a mechanism for sodium hyperabsorption in cystic fibrosis.
expression of Na-K ATPase and epithelial sodium channel
(2 times)
Medicine
(1 time)
ALI (1 time)
AQP1 (1 time)
BAL (1 time)
2007 [Effect of aldosterone on aquaporin and ionophorous protein expressions in guinea pig cochlea].
extrarenal epithelial sodium channel
(2 times)
Physiology
(1 time)
ECs (1 time)
EnNaC (1 time)
PROBE (1 time)
2011 Body fluid expansion in acromegaly is related to enhanced epithelial sodium channel (ENaC) activity.
10  alpha,beta,gamma-epithelial sodium channels
(1 time)
Biochemistry
(1 time)
CAP3 (1 time)
MAPs (1 time)
2012 Energetic and structural basis for activation of the epithelial sodium channel by matriptase.
11  alphabetagamma-epithelial Na+ channel
(1 time)
Pulmonary Medicine
(1 time)
--- 2004 cAMP-stimulated Na+ transport in H441 distal lung epithelial cells: role of PKA, phosphatidylinositol 3-kinase, and sgk1.
12  early aldosterone action on epithelial sodium channel
(1 time)
Molecular Biology
(1 time)
PI3Ks (1 time)
2014 Phosphoinositide 3-kinase pathway mediates early aldosterone action on morphology and epithelial sodium channel in mammalian renal epithelia.
13  EET-A inhibits epithelial sodium channel
(1 time)
Medicine
(1 time)
EET-A (2 times)
Ang II (1 time)
EETs (1 time)
2014 Epoxyeicosatrienoic acid analogue lowers blood pressure through vasodilation and sodium channel inhibition.
14  effect on Na(+) channel
(1 time)
Physiology
(1 time)
--- 2002 Segmental variability of ENaC subunit expression in rat colon during dietary sodium depletion.
15  effects against epithelial sodium channels
(1 time)
Chemistry
(1 time)
HMA (1 time)
uPA (1 time)
2018 6-Substituted Hexamethylene Amiloride (HMA) Derivatives as Potent and Selective Inhibitors of the Human Urokinase Plasminogen Activator for Use in Cancer.
16  electrogenic Na+ transport by the epithelial sodium channel
(1 time)
Biomedical Research
(1 time)
--- 2019 Potassium acts through mTOR to regulate its own secretion.
17  electrogenic, amiloride-sensitive, epithelial sodium channel
(1 time)
Nephrology
(1 time)
--- 2011 Vasopressin-dependent coupling between sodium transport and water flow in a mouse cortical collecting duct cell line.
18  Electroporation-mediated gene delivery of epithelial sodium channel
(1 time)
Cardiology
(1 time)
ARDS (1 time)
2015 Electroporation-mediated gene delivery of Na+,K+ -ATPase, and ENaC subunits to the lung attenuates acute respiratory distress syndrome in a two-hit porcine model.
19  ENaC/degenerin family of ion channels include the epithelial sodium channel
(1 time)
Physiology
(1 time)
ASICs (2 times)
2002 An external site controls closing of the epithelial Na+ channel ENaC.
20  ENaC/degenerin ion channel superfamily includes the amiloride-sensitive epithelial sodium channel
(1 time)
Biomedical Research
(1 time)
ASIC (1 time)
2016 Potential Roles of Amiloride-Sensitive Sodium Channels in Cancer Development.
21  encode alpha, beta or gamma subunit of epithelial sodium channels
(1 time)
Biochemistry
(1 time)
PHA (1 time)
PRA (1 time)
2008 Renin-aldosterone response, urinary Na/K ratio and growth in pseudohypoaldosteronism patients with mutations in epithelial sodium channel (ENaC) subunit genes.
22  encoding for a Na+ channel protein
(1 time)
Nephrology
(1 time)
--- 2010 Proteomics and tubulopathies.
23  Endiandrin A acts as co-stimulator of colonic epithelial sodium channels
(1 time)
Medicine
(1 time)
End A (1 time)
GR (1 time)
JNK (1 time)
2012 The plant-derived glucocorticoid receptor agonist Endiandrin A acts as co-stimulator of colonic epithelial sodium channels (ENaC) via SGK-1 and MAPKs.
24  endoluminal activation of the epithelial sodium channel
(1 time)
Physiology
(1 time)
--- 2019 Proteasuria-The impact of active urinary proteases on sodium retention in nephrotic syndrome.
25  enhanced amiloride sensitive Na+ conductance
(1 time)
Biochemistry
(1 time)
cAMP (1 time)
CFTR (1 time)
IBMX (1 time)
1997 Inhibition of epithelial Na+ currents by intracellular domains of the cystic fibrosis transmembrane conductance regulator.
26  enhanced plasma aldosterone, ileal activation of epithelial sodium channel
(1 time)
Gastroenterology
(1 time)
SGLT1 (1 time)
2005 Comparative study of epithelial gene expression in the small intestine among total proctocolectomized, dietary sodium-depleted, and aldosterone-infused rats.
27  enters through apical sodium channels
(1 time)
Allergy and Immunology
(1 time)
AECII (1 time)
ALI (1 time)
LPS (1 time)
2012 Sevoflurane reduces severity of acute lung injury possibly by impairing formation of alveolar oedema.
28  entry mechanism: the amiloride-sensitive Na(+) channel
(1 time)
Nephrology
(1 time)
--- 2006 A hypothesis linking sodium and lithium reabsorption in the distal nephron.
29  enzyme Na-K-ATPase or inhibit the epithelial sodium channel
(1 time)
Endocrine System Diseases
(1 time)
IR (1 time)
MS (1 time)
OLF (1 time)
2015 Identification of Putative Natriuretic Hormones Isolated from Human Urine.
30  epithelia express specific Na(+) channels
(1 time)
Biochemistry
(1 time)
CFTR (1 time)
2002 Where have all the Na+ channels gone? In search of functional ENaC in exocrine pancreas.
31  epithelial Na(+) channel subunit
(1 time)
Nephrology
(1 time)
DOT (1 time)
NAD (1 time)
2013 Epigenetics and the control of the collecting duct epithelial sodium channel.
32  epithelial Na+ channel complex
(1 time)
Physiology
(1 time)
RPA (1 time)
1998 Developmental regulation of epithelial sodium channel subunit mRNA expression in rat colon and lung.
33  epithelial sodium channel alpha-subunit
(1 time)
Neoplasms
(1 time)
ALI (1 time)
ASK1 (1 time)
HALI (1 time)
2016 SOCS-1 rescues IL-1beta-mediated suppression of epithelial sodium channel in mouse lung epithelial cells via ASK-1.
34  epithelial sodium channel sensitive to amiloride
(1 time)
Embryology
(1 time)
--- 2013 Expression of the epithelial sodium channel sensitive to amiloride (ENaC) in normal and preeclamptic human placenta.
35  epithelial type of Na(+) channel
(1 time)
Biochemistry
(1 time)
RVI (1 time)
2000 The hypertonicity-induced Na(+) conductance of rat hepatocytes: physiological significance and molecular correlate.
36  epithelium and the activity of alveolar Na(+) channel
(1 time)
Cell Biology
(1 time)
Ca (1 time)
2003 Large conductance Ca2+-activated K+ channels sense acute changes in oxygen tension in alveolar epithelial cells.
37  epithelium, we investigated the role of CFTR in regulating g
(1 time)
Physiology
(1 time)
CF (1 time)
CFTR (1 time)
2003 Functional interaction of CFTR and ENaC in sweat glands.
38  epithelium; and epithelial sodium channel
(1 time)
Natural Science Disciplines
(1 time)
AQPs (1 time)
2019 Distribution of aquaporins and sodium transporters in the gastrointestinal tract of a desert hare, Lepus yarkandensis.
39  ERRalpha, Na⁺/K⁺-ATPase and epithelial sodium channel
(1 time)
Chemistry
(1 time)
ChIP (1 time)
DS (1 time)
ERRalpha (1 time)
2016 High Salt Diet Affects Renal Sodium Excretion and ERRalpha Expression.
40  essential for epithelial sodium channel
(1 time)
Physiology
(1 time)
PLG (1 time)
uPA (1 time)
2019 Urokinase-type plasminogen activator (uPA) is not essential for epithelial sodium channel (ENaC)-mediated sodium retention in experimental nephrotic syndrome.
41  Estrogen negatively regulates the renal epithelial sodium channel
(1 time)
Biochemistry
(1 time)
--- 2019 Estrogen negatively regulates the renal epithelial sodium channel (ENaC) by promoting Derlin-1 expression and AMPK activation.
42  ethanol affects epithelial sodium channels
(1 time)
Cell Biology
(1 time)
ROS (1 time)
TEMPOL (1 time)
2012 Ethanol stimulates epithelial sodium channels by elevating reactive oxygen species.
43  examined activation of the human epithelial sodium channel
(1 time)
Biochemistry
(1 time)
microS (1 time)
2009 Alternative mechanism of activation of the epithelial na+ channel by cleavage.
44  examined the mechanism of amiloride-sensitive Na(+) channels
(1 time)
Endocrinology
(1 time)
--- 2007 Frog ANP increases the amiloride-sensitive Na(+) channel activity in urinary bladder cells of Japanese tree frog, Hyla japonica.
45  examines whether serine proteases can activate the amiloride-sensitive sodium channel
(1 time)
Nephrology
(1 time)
--- 2000 Activation of the amiloride-sensitive epithelial sodium channel by the serine protease mCAP1 expressed in a mouse cortical collecting duct cell line.
46  exchange, and both alveolar epithelial sodium channel
(1 time)
Cell Biology
(1 time)
AFC (1 time)
OA (1 time)
2013 Lipoxin A(4) activates alveolar epithelial sodium channel, Na,K-ATPase, and increases alveolar fluid clearance.
47  exchangers
(1 time)
Sexual Dysfunction, Physiological
(1 time)
CC (1 time)
EFS (1 time)
ICP (1 time)
2019 Amiloride Relaxes Rat Corpus Cavernosum Relaxation InVitro and Increases Intracavernous Pressure InVivo.
48  excretion and renal epithelial sodium channel
(1 time)
Vascular Diseases
(1 time)
HS (1 time)
TRPV1 (1 time)
WT (1 time)
2014 Transient receptor potential vanilloid 1 activation by dietary capsaicin promotes urinary sodium excretion by inhibiting epithelial sodium channel alpha subunit-mediated sodium reabsorption.
49  excretion by altering the activity of epithelial sodium channels
(1 time)
Receptors, Purinergic
(1 time)
BP (1 time)
RAAS (1 time)
2009 ENaC, renal sodium excretion and extracellular ATP.
50  explanation is that alcohol regulates epithelial sodium channels
(1 time)
Medicine
(1 time)
ARDS (1 time)
EtOH (1 time)
NOX (1 time)
2013 Ethanol alters alveolar fluid balance via Nadph oxidase (NOX) signaling to epithelial sodium channels (ENaC) in the lung.
51  expressed low-conductance amiloride sensitive sodium channels
(1 time)
Molecular Biology
(1 time)
--- 1998 Environmental KCl causes an upregulation of apical membrane maxi K and ENaC channels in everted Ambystoma collecting tubule.
52  expressed the amiloride-sensitive Na(+) channel
(1 time)
Nephrology
(1 time)
DCT (1 time)
mDCT (1 time)
NCC (1 time)
2004 In vitro characterization of aldosterone and cAMP effects in mouse distal convoluted tubule cells.
53  expression and cellular localization of epithelial sodium channel
(1 time)
Biochemistry
(1 time)
gamma2MSH (1 time)
MC3R (1 time)
2013 Gamma-melanocyte stimulating hormone regulates the expression and cellular localization of epithelial sodium channel in inner medullary collecting duct cells.
54  expression and modulation of the amiloride-sensitive epithelial sodium channel
(1 time)
Pulmonary Medicine
(1 time)
--- 2004 Spectrum of ion channels in alveolar epithelial cells: implications for alveolar fluid balance.
55  expression of amiloride sensitive sodium channels
(1 time)
Biochemistry
(1 time)
--- 2011 ENaC channels in oocytes from Xenopus laevis and their regulation by xShroom1 protein.
56  expression of apical Na+ channels
(1 time)
Pathology
(1 time)
UC (1 time)
2004 Decreased expression of apical Na+ channels and basolateral Na+, K+-ATPase in ulcerative colitis.
57  expression of AQP, Na+,K(+)-ATPase and the amiloride-sensitive Na+ channel
(1 time)
Physiology
(1 time)
AQP (1 time)
1997 Perinatal changes in expression of aquaporin-4 and other water and ion transporters in rat lung.
58  expression of epithelial sodium channel
(1 time)
Cardiology
(1 time)
ET-1 (1 time)
2006 Endothelin ETA receptor blockade with darusentan increases sodium and potassium excretion in aging rats.
59  expression of Na(+) channel
(1 time)
Cell Biology
(1 time)
HME (1 time)
2007 P2Y receptor regulation of sodium transport in human mammary epithelial cells.
60  number (N) and open probability (P(o)) of epithelial sodium channels
(1 time)
Biochemistry
(1 time)
GST (1 time)
S1A (1 time)
2004 Syntaxin 1A regulates ENaC channel activity.
61  well-established amiloride-sensitive Na(+) channel
(1 time)
Physiology
(1 time)
CNG (1 time)
PsTx (1 time)
2011 Alveolar epithelial CNGA1 channels mediate cGMP-stimulated, amiloride-insensitive, lung liquid absorption.