| 1 |
extracellular signal-regulated kinase
(14335 times)
|
Biochemistry
(2168 times)
|
MAPK (2557 times)
JNK (2205 times)
PI3K (947 times)
|
0 MAPK/ERK signal pathway alterations in patients with Langerhans Cell Histiocytosis.
|
| 2 |
externally regulated kinase
(4 times)
|
Psychophysiology
(1 time)
|
CDK2 (1 time)
GM-CSF (1 time)
IFN-gamma (1 time)
|
2006 ERK phosphorylation and FosB expression are associated with L-DOPA-induced dyskinesia in hemiparkinsonian mice.
|
| 3 |
early response kinase
(3 times)
|
Physiology
(1 time)
|
CAFs (1 time)
EMT (1 time)
ERK1 (1 time)
|
1999 Early response kinase and PI 3-kinase activation in adult cardiomyocytes and their role in hypertrophy.
|
| 4 |
ERK-MAPK
(3 times)
|
Biological Science Disciplines
(1 time)
|
eIF (1 time)
JNK (1 time)
PP1 (1 time)
|
2006 Active ERK contributes to protein translation by preventing JNK-dependent inhibition of protein phosphatase 1.
|
| 5 |
extracellular kinase
(3 times)
|
Cell Biology
(1 time)
|
COX-2 (1 time)
CRP (1 time)
GPx (1 time)
|
2013 Cannabinoid receptor agonists upregulate and enhance serotonin 2A (5-HT(2A)) receptor activity via ERK1/2 signaling.
|
| 6 |
extracellular signal-regulated mitogen-activated protein kinase
(3 times)
|
Physiology
(2 times)
|
FHL2 (1 time)
JNK (1 time)
LF (1 time)
|
2003 CD40 induces human multiple myeloma cell migration via phosphatidylinositol 3-kinase/AKT/NF-kappa B signaling.
|
| 7 |
expression levels of phosphorylated (p)‑extracellular signal‑regulated kinase
(2 times)
|
Molecular Biology
(2 times)
|
Ang II (1 time)
BDNF (1 time)
DM (1 time)
|
2018 Protection of Luteolin-7-O-glucoside against apoptosis induced by hypoxia/reoxygenation through the MAPK pathways in H9c2 cells.
|
| 8 |
extra-signal response kinase
(2 times)
|
Cell Biology
(1 time)
|
COX (1 time)
IL (1 time)
JNK (1 time)
|
2004 Neuronal differentiation of embryonic midbrain cells by upregulation of peroxisome proliferator-activated receptor-gamma via the JNK-dependent pathway.
|
| 9 |
downstream-phosphorylated signal-regulated kinase
(1 time)
|
Biomedical Research
(1 time)
|
ES (1 time)
JNK (1 time)
p-NF-kappaB (1 time)
|
2018 Electric Stimulation of Ear Reduces the Effect of Toll-Like Receptor 4 Signaling Pathway on Kainic Acid-Induced Epileptic Seizures in Rats.
|
| 10 |
E-NADPH-ketoglutarate species
(1 time)
|
Biochemistry
(1 time)
|
ERC (1 time)
ERI (1 time)
|
1998 Identification and characterization of kinetically competent carbinolamine and alpha-iminoglutarate complexes in the glutamate dehydrogenase-catalyzed oxidation of L-glutamate using a multiwavelength transient state approach.
|
| 11 |
early response regulated kinase
(1 time)
|
Cell Biology
(1 time)
|
uPA (1 time)
uPAR (1 time)
VN (1 time)
|
2005 Urokinase plasminogen activator receptor promotes macrophage infiltration into the vascular wall of ApoE deficient mice.
|
| 12 |
Eckmann, Ruelle and Khamporst
(1 time)
|
Cardiology
(1 time)
|
BP (1 time)
HRV (1 time)
|
1996 [Evaluation of the degree of diabetic dysautonomy with the analysis of heart rate measured at rest with the FINAPRES system].
|
| 13 |
effect of hypoxia on the phosphorylation of MAPK
(1 time)
|
Biochemistry
(1 time)
|
Bcl-2 (1 time)
|
2007 The role of Bax/Bcl-2 and pro-caspase peptides in hypoxia/reperfusion-dependent regulation of MAPK(ERK): discordant proteomic effect of MAPK(p38).
|
| 14 |
effectors phosphatidylinositol-3 kinase/AKT and p44/42 mitogen-activated protein kinases
(1 time)
|
Biochemistry
(1 time)
|
EGF (1 time)
EGFR (1 time)
|
2019 Nicotine exposure induces the proliferation of oral cancer cells through the alpha7 subunit of the nicotinic acetylcholine receptor.
|
| 15 |
EGFR, including phosphorylated (p‑AKT) and p‑
(1 time)
|
Genetics, Medical
(1 time)
|
EGFR (1 time)
NSCLC (1 time)
|
2019 Quinalizarin, a specific CK2 inhibitor, can reduce icotinib resistance in human lung adenocarcinoma cell lines.
|
| 16 |
EGFR/MAPK
(1 time)
|
Pathology
(1 time)
|
SCC (1 time)
|
2012 MAPK/ERK-dependent translation factor hyperactivation and dysregulated laminin gamma2 expression in oral dysplasia and squamous cell carcinoma.
|
| 17 |
Ekstrand, Ricketts and Kidd
(1 time)
|
Dentistry
(1 time)
|
ACDS (1 time)
ICDAS (1 time)
|
2019 Histological validation of the automated caries detection system (ACDS) in classifying occlusal caries with the ICDAS II system in vitro.
|
| 18 |
Ekstrand-Ricketts-Kidd
(1 time)
|
Dentistry
(1 time)
|
---
|
2009 Validity and reproducibility of ICDAS II in primary teeth.
|
| 19 |
Elk-related tyrosine kinase
(1 time)
|
Metabolism
(1 time)
|
DN (1 time)
JNK (1 time)
MEKK1 (1 time)
|
2008 JNK/c-Jun signaling mediates an anti-apoptotic effect of RANKL in osteoclasts.
|
| 20 |
enzymatic activation of mitogen activated protein kinase
(1 time)
|
Biochemistry
(1 time)
|
NLS (1 time)
PKCalpha (1 time)
TTA (1 time)
|
2002 Nuclear import of factors involved in signaling is inhibited in C3H/10T1/2 cells treated with tetradecylthioacetic acid.
|
| 21 |
epidermal growth factor via the MAP-kinase
(1 time)
|
Biochemistry
(1 time)
|
---
|
2006 ERK modulates DNA bending and enhancesome structure by phosphorylating HMG1-boxes 1 and 2 of the RNA polymerase I transcription factor UBF.
|
| 22 |
ERK by peroxynitrite is involved in the impaired MAPK
(1 time)
|
Gastroenterology
(1 time)
|
LPO (1 time)
PHT (1 time)
SO (1 time)
|
2008 Significance of ERK nitration in portal hypertensive gastropathy and its therapeutic implications.
|
| 23 |
ERK by peroxynitrite might alter MAPK
(1 time)
|
Gastroenterology
(1 time)
|
LPO (1 time)
PHT (1 time)
SO (1 time)
|
2008 Significance of ERK nitration in portal hypertensive gastropathy and its therapeutic implications.
|
| 24 |
ERK kinase (MEK)
(1 time)
|
Biocompatible Materials
(1 time)
|
BMPR (1 time)
BSP II (1 time)
Col-GAG (1 time)
|
2017 Nonmineralized and Mineralized Collagen Scaffolds Induce Differential Osteogenic Signaling Pathways in Human Mesenchymal Stem Cells.
|
| 25 |
established that B-Raf signaling through the MAP kinase
(1 time)
|
Cell Biology
(1 time)
|
siRNA (1 time)
|
2008 Knockdown of B-Raf impairs spindle formation and the mitotic checkpoint in human somatic cells.
|
| 26 |
establishing the proteomic distribution of MAPK
(1 time)
|
Biochemistry
(1 time)
|
AP (1 time)
ROB (1 time)
|
2007 Discordant tissue-specific expression of SAPK/MAPK(JNK)-related cofactors in hypoxia and hypoxia/reoxygenation in a model of anoxia-tolerance.
|
| 27 |
ET-1 and the phosphorylation of signal-regulated kinase
(1 time)
|
Biology
(1 time)
|
BNP (1 time)
mRVP (1 time)
SMA (1 time)
|
2018 STVNa attenuates right ventricle hypertrophy and pulmonary artery remodeling in rats induced by transverse aortic constriction.
|
| 28 |
event that boosts the mitogen-activated protein kinase
(1 time)
|
Biochemistry
(1 time)
|
PKC (1 time)
|
2000 Protein kinase C activation by acidic proteins including 14-3-3.
|
| 29 |
export of MAP kinase
(1 time)
|
Cell Biology
(1 time)
|
LMB (1 time)
MEK (1 time)
NES (1 time)
|
2000 Nuclear export of MAP kinase (ERK) involves a MAP kinase kinase (MEK)-dependent active transport mechanism.
|
| 30 |
expression and activation of AKT, but not mitogen-activated protein kinase
(1 time)
|
Biomedical Research
(1 time)
|
alpha-SMA (1 time)
ECM (1 time)
FC (1 time)
|
2017 Fibrillar Type I Collagen Enhances the Differentiation and Proliferation of Myofibroblasts by Lowering alpha2beta1 Integrin Expression in Cardiac Fibrosis.
|
| 31 |
expression and an increase phosphorylated‑extracellular signal regulated kinase
(1 time)
|
Molecular Biology
(1 time)
|
iNOS (1 time)
MMP (1 time)
PGE2 (1 time)
|
2017 D-limonene exhibits anti-inflammatory and antioxidant properties in an ulcerative colitis rat model via regulation of iNOS, COX-2, PGE2 and ERK signaling pathways.
|
| 32 |
expression and inhibitingextracellular-signal-regulated kinase
(1 time)
|
Cell Biology
(1 time)
|
ALI (1 time)
ARDS (1 time)
LPS (1 time)
|
2019 Tannic acid protects against experimental acute lung injury through downregulation of TLR4 and MAPK.
|
| 33 |
expression of MAPK
(1 time)
|
Biochemistry
(1 time)
|
AP (1 time)
ROB (1 time)
|
2007 Discordant tissue-specific expression of SAPK/MAPK(JNK)-related cofactors in hypoxia and hypoxia/reoxygenation in a model of anoxia-tolerance.
|
| 34 |
expression of the intercellular signal-regulated kinases
(1 time)
|
Chemistry
(1 time)
|
GLUT2 (1 time)
IR (1 time)
IRS-1 (1 time)
|
2012 Fraction from wax apple [Syzygium samarangense (Blume) Merrill and Perry] fruit extract ameliorates insulin resistance via modulating insulin signaling and inflammation pathway in tumor necrosis factor alpha-treated FL83B mouse hepatocytes.
|
| 35 |
expression of TLR-2, phosphorylation of MAPKs
(1 time)
|
Biotechnology
(1 time)
|
iNOS (1 time)
|
2019 Micronized and Heat-Treated Lactobacillus plantarum LM1004 Stimulates Host Immune Responses Via the TLR-2/MAPK/NF-kappaB Signalling Pathway In Vitro and In Vivo.
|
| 36 |
expression regulation knowledge
(1 time)
|
Neurology
(1 time)
|
---
|
2007 Linking children's neuropsychological processing of emotion with their knowledge of emotion expression regulation.
|
| 37 |
external receptor kinase
(1 time)
|
Toxicology
(1 time)
|
CASPASE-8 (1 time)
IL-1beta (1 time)
iNOS (1 time)
|
2007 Effects of bacterial toxins on endothelial tight junction in vitro: a mechanism-based investigation.
|
| 38 |
extracellular growth factor-regulated kinase
(1 time)
|
Microbiology
(1 time)
|
IL-8 (1 time)
PI3K (1 time)
|
2005 A phosphatidyl-inositol-3-kinase-dependent anti-inflammatory pathway activated by Salmonella in epithelial cells.
|
| 39 |
extracellular protein kinase
(1 time)
|
Molecular Biology
(1 time)
|
Abeta25-35 (1 time)
AD (1 time)
AST (1 time)
|
2016 Beneficial Effect of Astragaloside on Alzheimer's Disease Condition Using Cultured Primary Cortical Cells Under beta-amyloid Exposure.
|
| 40 |
extracellular regulated signal-activated kinase
(1 time)
|
Histocytochemistry
(1 time)
|
GC (1 time)
HER2 (1 time)
JNK (1 time)
|
2019 Human Epidermal Growth Factor Receptor-2 Promotes Invasion and Metastasis in Gastric Cancer by Activating Mitogen-activated Protein Kinase Signaling.
|
| 41 |
extracellular regulatory kinase activation
(1 time)
|
Biology
(1 time)
|
EGF (1 time)
NGF (1 time)
|
2017 A combined model reduction algorithm for controlled biochemical systems.
|
| 42 |
extracellular signal conditioning kinase
(1 time)
|
Neoplasms
(1 time)
|
EGFR (1 time)
|
2013 [Molecular mechanism of chemosensitization to paclitaxel in human melanoma cells induced by targeting the EGFR signaling pathway].
|
| 43 |
Extracellular-Signal-regulated-Kinase kinase
(1 time)
|
Pharmacology
(1 time)
|
BSA (1 time)
|
2011 Advanced-glycation-end-product-cholesterol-aggregated-protein accelerates the proliferation of mesangial cells mediated by transforming-growth-factor-beta 1 receptors and the ERK-MAPK pathway.
|
| 44 |
influence signal-regulated kinase
(1 time)
|
Biochemistry
(1 time)
|
CCP (1 time)
JNK (1 time)
LDH (1 time)
|
2019 Inhibiting c-Jun N-terminal kinase (JNK)-mediated apoptotic signaling pathway in PC12 cells by a polysaccharide (CCP) from Coptis chinensis against Amyloid-beta (Abeta)-induced neurotoxicity.
|
| 45 |
L-Carnitine rescues ketamine-induced attenuated heart rate and MAPK
(1 time)
|
Embryology
(1 time)
|
NMDA (1 time)
|
2012 L-Carnitine rescues ketamine-induced attenuated heart rate and MAPK (ERK) activity in zebrafish embryos.
|
| 46 |
Ras-Raf-MEK-ERK
(1 time)
|
Antineoplastic Agents
(1 time)
|
---
|
2005 Raf kinase as a target for anticancer therapeutics.
|
| 47 |
receptor-mediated signal-regulated kinase
(1 time)
|
Allergy and Immunology
(1 time)
|
RBL-CXCR1 (1 time)
|
2009 Differential activation and regulation of CXCR1 and CXCR2 by CXCL8 monomer and dimer.
|
| 48 |
signal-related regulated kinase
(1 time)
|
Biochemistry
(1 time)
|
ADO (1 time)
ARs (1 time)
MEK (1 time)
|
2010 Protein kinase Cmu mediates adenosine-stimulated steroidogenesis in primary rat adrenal cells.
|
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