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Abbreviation: ERK
Appearance Frequency: 13590 time(s)
Long forms: 45

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Long Form No. Long Form Research Area Co-occurring Abbreviation PubMed/MEDLINE Info. (Year, Title)
extracellular signal-regulated kinase
(13535 times)
Biochemistry
(2081 times)
MAPK (2406 times)
JNK (2089 times)
PI3K (890 times)
1992 Evidence for a Ras-dependent extracellular signal-regulated protein kinase (ERK) cascade.
external regulated kinases
(4 times)
Psychophysiology
(1 time)
CDK2 (1 time)
GM-CSF (1 time)
IFN-gamma (1 time)
2006 ERK phosphorylation and FosB expression are associated with L-DOPA-induced dyskinesia in hemiparkinsonian mice.
early response kinase
(3 times)
Physiology
(1 time)
CAFs (1 time)
EMT (1 time)
ERK1 (1 time)
1999 Early response kinase and PI 3-kinase activation in adult cardiomyocytes and their role in hypertrophy.
ERK/MAPK
(3 times)
Biological Science Disciplines
(1 time)
eIF (1 time)
JNK (1 time)
PP1 (1 time)
2006 Active ERK contributes to protein translation by preventing JNK-dependent inhibition of protein phosphatase 1.
extracellular signal-regulated mitogen-activated protein kinase
(3 times)
Physiology
(2 times)
FHL2 (1 time)
JNK (1 time)
LF (1 time)
2003 CD40 induces human multiple myeloma cell migration via phosphatidylinositol 3-kinase/AKT/NF-kappa B signaling.
extra-signal response kinase
(2 times)
Cell Biology
(1 time)
COX (1 time)
IL (1 time)
JNK (1 time)
2004 Neuronal differentiation of embryonic midbrain cells by upregulation of peroxisome proliferator-activated receptor-gamma via the JNK-dependent pathway.
extracellular kinase
(2 times)
Neurology
(1 time)
COX-2 (1 time)
CRP (1 time)
GPx (1 time)
2013 Cannabinoid receptor agonists upregulate and enhance serotonin 2A (5-HT(2A)) receptor activity via ERK1/2 signaling.
downstream-phosphorylated signal-regulated kinase
(1 time)
Biomedical Research
(1 time)
ES (1 time)
JNK (1 time)
pNF-kappaB (1 time)
2018 Electric Stimulation of Ear Reduces the Effect of Toll-Like Receptor 4 Signaling Pathway on Kainic Acid-Induced Epileptic Seizures in Rats.
E-NADPH-ketoglutarate species
(1 time)
Biochemistry
(1 time)
ERC (1 time)
ERI (1 time)
1998 Identification and characterization of kinetically competent carbinolamine and alpha-iminoglutarate complexes in the glutamate dehydrogenase-catalyzed oxidation of L-glutamate using a multiwavelength transient state approach.
10  early response regulated kinase
(1 time)
Cell Biology
(1 time)
uPA (1 time)
uPAR (1 time)
VN (1 time)
2005 Urokinase plasminogen activator receptor promotes macrophage infiltration into the vascular wall of ApoE deficient mice.
11  Eckmann, Ruelle and Khamporst
(1 time)
Cardiology
(1 time)
BP (1 time)
HRV (1 time)
1996 [Evaluation of the degree of diabetic dysautonomy with the analysis of heart rate measured at rest with the FINAPRES system].
12  effect of hypoxia on the phosphorylation of MAPK
(1 time)
Biochemistry
(1 time)
Bcl-2 (1 time)
2007 The role of Bax/Bcl-2 and pro-caspase peptides in hypoxia/reperfusion-dependent regulation of MAPK(ERK): discordant proteomic effect of MAPK(p38).
13  EGFR/MAPK
(1 time)
Pathology
(1 time)
SCC (1 time)
2012 MAPK/ERK-dependent translation factor hyperactivation and dysregulated laminin gamma2 expression in oral dysplasia and squamous cell carcinoma.
14  Ekstrand, Ricketts and Kidd
(1 time)
Dentistry
(1 time)
ACDS (1 time)
ICDAS (1 time)
2018 Histological validation of the automated caries detection system (ACDS) in classifying occlusal caries with the ICDAS II system in vitro.
15  Ekstrand-Ricketts-Kidd
(1 time)
Dentistry
(1 time)
--- 2009 Validity and reproducibility of ICDAS II in primary teeth.
16  elevated growth rate through their activation of the MAP kinase
(1 time)
Cell Biology
(1 time)
N-region (1 time)
2017 Phosphorylation of the C-Raf N-region promotes Raf dimerization.
17  Elk-related tyrosine kinase
(1 time)
Metabolism
(1 time)
DN (1 time)
JNK (1 time)
MEKK1 (1 time)
2008 JNK/c-Jun signaling mediates an anti-apoptotic effect of RANKL in osteoclasts.
18  enzymatic activation of mitogen activated protein kinase
(1 time)
Biochemistry
(1 time)
NLS (1 time)
PKCalpha (1 time)
TTA (1 time)
2002 Nuclear import of factors involved in signaling is inhibited in C3H/10T1/2 cells treated with tetradecylthioacetic acid.
19  epidermal growth factor via the MAP-kinase
(1 time)
Biochemistry
(1 time)
--- 2006 ERK modulates DNA bending and enhancesome structure by phosphorylating HMG1-boxes 1 and 2 of the RNA polymerase I transcription factor UBF.
20  ERK by peroxynitrite is involved in the impaired MAPK
(1 time)
Gastroenterology
(1 time)
LPO (1 time)
PHT (1 time)
SO (1 time)
2008 Significance of ERK nitration in portal hypertensive gastropathy and its therapeutic implications.
21  ERK by peroxynitrite might alter MAPK
(1 time)
Gastroenterology
(1 time)
LPO (1 time)
PHT (1 time)
SO (1 time)
2008 Significance of ERK nitration in portal hypertensive gastropathy and its therapeutic implications.
22  ERK kinase (MEK)
(1 time)
Biocompatible Materials
(1 time)
BMPR (1 time)
BSP II (1 time)
Col-GAG (1 time)
2017 Nonmineralized and Mineralized Collagen Scaffolds Induce Differential Osteogenic Signaling Pathways in Human Mesenchymal Stem Cells.
23  established that B-Raf signaling through the MAP kinase
(1 time)
Cell Biology
(1 time)
siRNA (1 time)
2008 Knockdown of B-Raf impairs spindle formation and the mitotic checkpoint in human somatic cells.
24  establishing the proteomic distribution of MAPK
(1 time)
Biochemistry
(1 time)
AP (1 time)
ROB (1 time)
2007 Discordant tissue-specific expression of SAPK/MAPK(JNK)-related cofactors in hypoxia and hypoxia/reoxygenation in a model of anoxia-tolerance.
25  ET-1 and the phosphorylation of signal-regulated kinase
(1 time)
Biology
(1 time)
BNP (1 time)
mRVP (1 time)
SMA (1 time)
2018 STVNa attenuates right ventricle hypertrophy and pulmonary artery remodeling in rats induced by transverse aortic constriction.
26  event that boosts the mitogen-activated protein kinase
(1 time)
Biochemistry
(1 time)
PKC (1 time)
2000 Protein kinase C activation by acidic proteins including 14-3-3.
27  export of MAP kinase
(1 time)
Cell Biology
(1 time)
LMB (1 time)
MEK (1 time)
NES (1 time)
2000 Nuclear export of MAP kinase (ERK) involves a MAP kinase kinase (MEK)-dependent active transport mechanism.
28  expression and activation of AKT, but not mitogen-activated protein kinase
(1 time)
Biomedical Research
(1 time)
alpha-SMA (1 time)
ECM (1 time)
FC (1 time)
2017 Fibrillar Type I Collagen Enhances the Differentiation and Proliferation of Myofibroblasts by Lowering alpha2beta1 Integrin Expression in Cardiac Fibrosis.
29  expression and an increase phosphorylated‑extracellular signal regulated kinase
(1 time)
Molecular Biology
(1 time)
iNOS (1 time)
MMP (1 time)
PGE2 (1 time)
2017 D-limonene exhibits anti-inflammatory and antioxidant properties in an ulcerative colitis rat model via regulation of iNOS, COX-2, PGE2 and ERK signaling pathways.
30  expression and inhibitingextracellular-signal-regulated kinase
(1 time)
Cell Biology
(1 time)
ALI (1 time)
ARDS (1 time)
LPS (1 time)
2018 Tannic acid protects against experimental acute lung injury through downregulation of TLR4 and MAPK.
31  expression of MAPK
(1 time)
Biochemistry
(1 time)
AP (1 time)
ROB (1 time)
2007 Discordant tissue-specific expression of SAPK/MAPK(JNK)-related cofactors in hypoxia and hypoxia/reoxygenation in a model of anoxia-tolerance.
32  expression of phosphorylated (p)‑extracellular signal‑regulated kinas
(1 time)
Molecular Biology
(1 time)
Ang II (1 time)
LUTG (1 time)
2018 Protection of Luteolin-7-O-glucoside against apoptosis induced by hypoxia/reoxygenation through the MAPK pathways in H9c2 cells.
33  expression of the intercellular signal-regulated kinases
(1 time)
Chemistry
(1 time)
GLUT2 (1 time)
IR (1 time)
IRS-1 (1 time)
2012 Fraction from wax apple [Syzygium samarangense (Blume) Merrill and Perry] fruit extract ameliorates insulin resistance via modulating insulin signaling and inflammation pathway in tumor necrosis factor alpha-treated FL83B mouse hepatocytes.
34  expression regulation knowledge
(1 time)
Neurology
(1 time)
--- 2007 Linking children's neuropsychological processing of emotion with their knowledge of emotion expression regulation.
35  external receptor kinase
(1 time)
Toxicology
(1 time)
CASPASE-8 (1 time)
IL-1beta (1 time)
iNOS (1 time)
2007 Effects of bacterial toxins on endothelial tight junction in vitro: a mechanism-based investigation.
36  extracellular growth factor-regulated kinase
(1 time)
Microbiology
(1 time)
IL-8 (1 time)
PI3K (1 time)
2005 A phosphatidyl-inositol-3-kinase-dependent anti-inflammatory pathway activated by Salmonella in epithelial cells.
37  extracellular protein kinase
(1 time)
Molecular Biology
(1 time)
Abeta25-35 (1 time)
AD (1 time)
AST (1 time)
2016 Beneficial Effect of Astragaloside on Alzheimer's Disease Condition Using Cultured Primary Cortical Cells Under beta-amyloid Exposure.
38  extracellular regulated signal-activated kinase
(1 time)
Histocytochemistry
(1 time)
GC (1 time)
HER2 (1 time)
JNK (1 time)
2018 Human Epidermal Growth Factor Receptor-2 Promotes Invasion and Metastasis in Gastric Cancer by Activating Mitogen-activated Protein Kinase Signaling.
39  extracellular regulatory kinase activation
(1 time)
Biology
(1 time)
EGF (1 time)
NGF (1 time)
2017 A combined model reduction algorithm for controlled biochemical systems.
40  extracellular signal conditioning kinase
(1 time)
Neoplasms
(1 time)
EGFR (1 time)
2013 [Molecular mechanism of chemosensitization to paclitaxel in human melanoma cells induced by targeting the EGFR signaling pathway].
41  Extracellular-Signal-regulated-Kinase kinase
(1 time)
Pharmacology
(1 time)
BSA (1 time)
2011 Advanced-glycation-end-product-cholesterol-aggregated-protein accelerates the proliferation of mesangial cells mediated by transforming-growth-factor-beta 1 receptors and the ERK-MAPK pathway.
42  L-Carnitine rescues ketamine-induced attenuated heart rate and MAPK
(1 time)
Embryology
(1 time)
NMDA (1 time)
2012 L-Carnitine rescues ketamine-induced attenuated heart rate and MAPK (ERK) activity in zebrafish embryos.
43  Ras-Raf-MEK-ERK
(1 time)
Antineoplastic Agents
(1 time)
--- 2005 Raf kinase as a target for anticancer therapeutics.
44  receptor-mediated signal-regulated kinase
(1 time)
Allergy and Immunology
(1 time)
RBL-CXCR1 (1 time)
2009 Differential activation and regulation of CXCR1 and CXCR2 by CXCL8 monomer and dimer.
45  signal-related regulated kinase
(1 time)
Biochemistry
(1 time)
ADO (1 time)
ARs (1 time)
MEK (1 time)
2010 Protein kinase Cmu mediates adenosine-stimulated steroidogenesis in primary rat adrenal cells.