1 |
extracellular signal-regulated kinase
(14974 times)
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Biochemistry (2222 times)
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MAPK (2673 times) JNK (2319 times) PI3K (988 times)
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1992 Evidence for a Ras-dependent extracellular signal-regulated protein kinase (ERK) cascade.
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2 |
external regulated kinases
(4 times)
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Geriatrics (1 time)
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CDK2 (1 time) GM-CSF (1 time) IFN-gamma (1 time)
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2005 ERK phosphorylation and FosB expression are associated with L-DOPA-induced dyskinesia in hemiparkinsonian mice.
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3 |
early response kinase
(3 times)
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Physiology (1 time)
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CAFs (1 time) EMT (1 time) ERK1 (1 time)
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1999 Early response kinase and PI 3-kinase activation in adult cardiomyocytes and their role in hypertrophy.
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4 |
ERK-MAPK
(3 times)
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Biological Science Disciplines (1 time)
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eIF (1 time) JNK (1 time) PP1 (1 time)
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2006 Active ERK contributes to protein translation by preventing JNK-dependent inhibition of protein phosphatase 1.
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5 |
extracellular kinase
(3 times)
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Cell Biology (1 time)
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COX-2 (1 time) CRP (1 time) GPx (1 time)
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2012 Cannabinoid receptor agonists upregulate and enhance serotonin 2A (5-HT(2A)) receptor activity via ERK1/2 signaling.
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6 |
extracellular signal-regulated mitogen-activated protein kinase
(3 times)
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Physiology (2 times)
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FHL2 (1 time) JNK (1 time) LF (1 time)
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2002 CD40 induces human multiple myeloma cell migration via phosphatidylinositol 3-kinase/AKT/NF-kappa B signaling.
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7 |
expression levels of phosphorylated (p)extracellular signalregulated kinase
(2 times)
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Molecular Biology (2 times)
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Ang II (1 time) BDNF (1 time) DM (1 time)
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2018 Protection of Luteolin-7-O-glucoside against apoptosis induced by hypoxia/reoxygenation through the MAPK pathways in H9c2 cells.
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8 |
extra-signal response kinase
(2 times)
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Cell Biology (1 time)
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COX (1 time) IL (1 time) JNK (1 time)
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2004 Neuronal differentiation of embryonic midbrain cells by upregulation of peroxisome proliferator-activated receptor-gamma via the JNK-dependent pathway.
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9 |
extracellular protein kinases
(2 times)
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Molecular Biology (1 time)
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Abeta25-35 (1 time) AD (1 time) AST (1 time)
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2015 Beneficial Effect of Astragaloside on Alzheimer's Disease Condition Using Cultured Primary Cortical Cells Under beta-amyloid Exposure.
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10 |
downstream-phosphorylated signal-regulated kinase
(1 time)
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Biomedical Research (1 time)
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ES (1 time) JNK (1 time) p-NF-kappaB (1 time)
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2018 Electric Stimulation of Ear Reduces the Effect of Toll-Like Receptor 4 Signaling Pathway on Kainic Acid-Induced Epileptic Seizures in Rats.
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11 |
E-NADPH-ketoglutarate species
(1 time)
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Biochemistry (1 time)
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ERC (1 time) ERI (1 time)
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1998 Identification and characterization of kinetically competent carbinolamine and alpha-iminoglutarate complexes in the glutamate dehydrogenase-catalyzed oxidation of L-glutamate using a multiwavelength transient state approach.
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12 |
early response regulated kinase
(1 time)
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Cell Biology (1 time)
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uPA (1 time) uPAR (1 time) VN (1 time)
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2004 Urokinase plasminogen activator receptor promotes macrophage infiltration into the vascular wall of ApoE deficient mice.
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13 |
Eckmann, Ruelle and Khamporst
(1 time)
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Cardiology (1 time)
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BP (1 time) HRV (1 time)
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1996 [Evaluation of the degree of diabetic dysautonomy with the analysis of heart rate measured at rest with the FINAPRES system].
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14 |
effect of hypoxia on the phosphorylation of MAPK
(1 time)
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Biochemistry (1 time)
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Bcl-2 (1 time)
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2007 The role of Bax/Bcl-2 and pro-caspase peptides in hypoxia/reperfusion-dependent regulation of MAPK(ERK): discordant proteomic effect of MAPK(p38).
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15 |
effectors phosphatidylinositol-3 kinase/AKT and p44/42 mitogen-activated protein kinases
(1 time)
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Biochemistry (1 time)
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EGF (1 time) EGFR (1 time)
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2019 Nicotine exposure induces the proliferation of oral cancer cells through the alpha7 subunit of the nicotinic acetylcholine receptor.
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16 |
EGFR, including phosphorylated (pAKT) and p
(1 time)
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Genetics, Medical (1 time)
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EGFR (1 time) NSCLC (1 time)
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2019 Quinalizarin, a specific CK2 inhibitor, can reduce icotinib resistance in human lung adenocarcinoma cell lines.
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17 |
EGFR/MAPK
(1 time)
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Pathology (1 time)
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SCC (1 time)
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2012 MAPK/ERK-dependent translation factor hyperactivation and dysregulated laminin gamma2 expression in oral dysplasia and squamous cell carcinoma.
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18 |
Ekstrand, Ricketts and Kidd
(1 time)
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Dentistry (1 time)
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ACDS (1 time) ICDAS (1 time)
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2018 Histological validation of the automated caries detection system (ACDS) in classifying occlusal caries with the ICDAS II system in vitro.
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19 |
Ekstrand-Ricketts-Kidd
(1 time)
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Dentistry (1 time)
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---
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2009 Validity and reproducibility of ICDAS II in primary teeth.
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20 |
Elk-related tyrosine kinase
(1 time)
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Metabolism (1 time)
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DN (1 time) JNK (1 time) MEKK1 (1 time)
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2008 JNK/c-Jun signaling mediates an anti-apoptotic effect of RANKL in osteoclasts.
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21 |
enzymatic activation of mitogen activated protein kinase
(1 time)
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Biochemistry (1 time)
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NLS (1 time) PKCalpha (1 time) TTA (1 time)
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2002 Nuclear import of factors involved in signaling is inhibited in C3H/10T1/2 cells treated with tetradecylthioacetic acid.
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22 |
epidermal growth factor via the MAP-kinase
(1 time)
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Biochemistry (1 time)
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---
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2006 ERK modulates DNA bending and enhancesome structure by phosphorylating HMG1-boxes 1 and 2 of the RNA polymerase I transcription factor UBF.
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23 |
ERK by peroxynitrite is involved in the impaired MAPK
(1 time)
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Gastroenterology (1 time)
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LPO (1 time) PHT (1 time) SO (1 time)
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2008 Significance of ERK nitration in portal hypertensive gastropathy and its therapeutic implications.
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24 |
ERK by peroxynitrite might alter MAPK
(1 time)
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Gastroenterology (1 time)
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LPO (1 time) PHT (1 time) SO (1 time)
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2008 Significance of ERK nitration in portal hypertensive gastropathy and its therapeutic implications.
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25 |
ERK kinase (MEK)
(1 time)
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Biocompatible Materials (1 time)
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BMPR (1 time) BSP II (1 time) Col-GAG (1 time)
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2017 Nonmineralized and Mineralized Collagen Scaffolds Induce Differential Osteogenic Signaling Pathways in Human Mesenchymal Stem Cells.
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26 |
Erkodent Erich Kopp, Pfalzgrafenweiler Germany
(1 time)
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ATR-FTIR (1 time) PETG (1 time) RAS (1 time)
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2020 ATR-FTIR Analysis and One-Week Stress Relaxation of Four Orthodontic Aligner Materials.
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27 |
Erkodur
(1 time)
|
|
CAM (1 time) COP (1 time) DUR (1 time)
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2020 Initial Bacterial Adhesion and Biofilm Formation on Aligner Materials.
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28 |
established that B-Raf signaling through the MAP kinase
(1 time)
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Cell Biology (1 time)
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siRNA (1 time)
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2008 Knockdown of B-Raf impairs spindle formation and the mitotic checkpoint in human somatic cells.
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29 |
establishing the proteomic distribution of MAPK
(1 time)
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Biochemistry (1 time)
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AP (1 time) ROB (1 time)
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2007 Discordant tissue-specific expression of SAPK/MAPK(JNK)-related cofactors in hypoxia and hypoxia/reoxygenation in a model of anoxia-tolerance.
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30 |
ET-1 and the phosphorylation of signal-regulated kinase
(1 time)
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Biology (1 time)
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BNP (1 time) mRVP (1 time) SMA (1 time)
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2018 STVNa attenuates right ventricle hypertrophy and pulmonary artery remodeling in rats induced by transverse aortic constriction.
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31 |
event that boosts the mitogen-activated protein kinase
(1 time)
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Biochemistry (1 time)
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PKC (1 time)
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2000 Protein kinase C activation by acidic proteins including 14-3-3.
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32 |
export of MAP kinase
(1 time)
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Cell Biology (1 time)
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LMB (1 time) MEK (1 time) NES (1 time)
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2000 Nuclear export of MAP kinase (ERK) involves a MAP kinase kinase (MEK)-dependent active transport mechanism.
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33 |
expression and activation of AKT, but not mitogen-activated protein kinase
(1 time)
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Biomedical Research (1 time)
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alpha-SMA (1 time) ECM (1 time) FC (1 time)
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2017 Fibrillar Type I Collagen Enhances the Differentiation and Proliferation of Myofibroblasts by Lowering alpha2beta1 Integrin Expression in Cardiac Fibrosis.
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34 |
expression and an increase phosphorylatedextracellular signal regulated kinase
(1 time)
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Molecular Biology (1 time)
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iNOS (1 time) MMP (1 time) PGE2 (1 time)
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2017 D-limonene exhibits anti-inflammatory and antioxidant properties in an ulcerative colitis rat model via regulation of iNOS, COX-2, PGE2 and ERK signaling pathways.
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35 |
expression and inhibitingextracellular-signal-regulated kinase
(1 time)
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Cell Biology (1 time)
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ALI (1 time) ARDS (1 time) LPS (1 time)
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2018 Tannic acid protects against experimental acute lung injury through downregulation of TLR4 and MAPK.
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36 |
expression levels of pextracellular signalregulated kinase
(1 time)
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Neoplasms (1 time)
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ISO (1 time) MAPK (1 time) NAC (1 time)
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2020 Isoorientin induces the apoptosis and cell cycle arrest of A549 human lung cancer cells via the ROS‑regulated MAPK, STAT3 and NF‑kappaB signaling pathways.
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37 |
expression of MAPK
(1 time)
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Biochemistry (1 time)
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AP (1 time) ROB (1 time)
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2007 Discordant tissue-specific expression of SAPK/MAPK(JNK)-related cofactors in hypoxia and hypoxia/reoxygenation in a model of anoxia-tolerance.
|
38 |
expression of the intercellular signal-regulated kinases
(1 time)
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Chemistry (1 time)
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GLUT2 (1 time) IR (1 time) IRS-1 (1 time)
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2012 Fraction from wax apple [Syzygium samarangense (Blume) Merrill and Perry] fruit extract ameliorates insulin resistance via modulating insulin signaling and inflammation pathway in tumor necrosis factor alpha-treated FL83B mouse hepatocytes.
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39 |
expression of TLR-2, phosphorylation of MAPKs
(1 time)
|
Biotechnology (1 time)
|
iNOS (1 time)
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2019 Micronized and Heat-Treated Lactobacillus plantarum LM1004 Stimulates Host Immune Responses Via the TLR-2/MAPK/NF-kappaB Signalling Pathway In Vitro and In Vivo.
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40 |
expression regulation knowledge
(1 time)
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Neurology (1 time)
|
---
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2007 Linking children's neuropsychological processing of emotion with their knowledge of emotion expression regulation.
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41 |
expressions of genes of the MAPK pathway
(1 time)
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Biology (1 time)
|
ROS (1 time) SOD (1 time)
|
2020 Polystyrene nanoplastic induces ROS production and affects the MAPK-HIF-1/NFkB-mediated antioxidant system in Daphnia pulex.
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42 |
external receptor kinase
(1 time)
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Toxicology (1 time)
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CASPASE-8 (1 time) IL-1beta (1 time) iNOS (1 time)
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2007 Effects of bacterial toxins on endothelial tight junction in vitro: a mechanism-based investigation.
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43 |
extracellular regulated signal-activated kinase
(1 time)
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Histocytochemistry (1 time)
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GC (1 time) HER2 (1 time) JNK (1 time)
|
2018 Human Epidermal Growth Factor Receptor-2 Promotes Invasion and Metastasis in Gastric Cancer by Activating Mitogen-activated Protein Kinase Signaling.
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44 |
extracellular regulatory kinase activation
(1 time)
|
Biology (1 time)
|
EGF (1 time) NGF (1 time)
|
2017 A combined model reduction algorithm for controlled biochemical systems.
|
45 |
extracellular signal conditioning kinase
(1 time)
|
Neoplasms (1 time)
|
EGFR (1 time)
|
2013 [Molecular mechanism of chemosensitization to paclitaxel in human melanoma cells induced by targeting the EGFR signaling pathway].
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46 |
Extracellular-Signal-regulated-Kinase kinase
(1 time)
|
Pharmacology (1 time)
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BSA (1 time)
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2011 Advanced-glycation-end-product-cholesterol-aggregated-protein accelerates the proliferation of mesangial cells mediated by transforming-growth-factor-beta 1 receptors and the ERK-MAPK pathway.
|
47 |
influence signal-regulated kinase
(1 time)
|
Biochemistry (1 time)
|
CCP (1 time) JNK (1 time) LDH (1 time)
|
2019 Inhibiting c-Jun N-terminal kinase (JNK)-mediated apoptotic signaling pathway in PC12 cells by a polysaccharide (CCP) from Coptis chinensis against Amyloid-beta (Abeta)-induced neurotoxicity.
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48 |
L-Carnitine rescues ketamine-induced attenuated heart rate and MAPK
(1 time)
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Embryology (1 time)
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NMDA (1 time)
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2011 L-Carnitine rescues ketamine-induced attenuated heart rate and MAPK (ERK) activity in zebrafish embryos.
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49 |
Ras-Raf-MEK-ERK
(1 time)
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Antineoplastic Agents (1 time)
|
---
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2005 Raf kinase as a target for anticancer therapeutics.
|
50 |
receptor-mediated signal-regulated kinase
(1 time)
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Allergy and Immunology (1 time)
|
RBL-CXCR1 (1 time)
|
2009 Differential activation and regulation of CXCR1 and CXCR2 by CXCL8 monomer and dimer.
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51 |
signal-related regulated kinase
(1 time)
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Biochemistry (1 time)
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ADO (1 time) ARs (1 time) MEK (1 time)
|
2010 Protein kinase Cmu mediates adenosine-stimulated steroidogenesis in primary rat adrenal cells.
|