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Abbreviation: HBx
Appearance Frequency: 763 time(s)
Long forms: 35

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Long Form No. Long Form Research Area Co-occurring Abbreviation PubMed/MEDLINE Info. (Year, Title)
hepatitis B virus X protein
(377 times)
Neoplasms
(84 times)
HCC (169 times)
HBV (101 times)
HIF-1alpha (12 times)
1989 Dimerization of hepatitis B viral X protein synthesized in a cell-free system.
HBV X protein
(155 times)
Neoplasms
(35 times)
HBV (133 times)
HCC (79 times)
NF-kappaB (7 times)
1996 Hepatitis B virus X protein partially substitutes for E1A transcriptional function during adenovirus infection.
hepatitis B virus X
(112 times)
Gastroenterology
(18 times)
HCC (42 times)
HBV (32 times)
HPCs (4 times)
1995 An antisense promoter within the hepatitis B virus X gene.
hepatitis B x protein
(25 times)
Gastroenterology
(8 times)
HBV (18 times)
HCC (13 times)
cccDNA (2 times)
1998 Hepatitis B x protein inhibits p53-dependent DNA repair in primary mouse hepatocytes.
HBV X
(20 times)
Virology
(5 times)
HBV (16 times)
HCC (10 times)
CP (2 times)
2002 Virus replication and virion export in X-deficient hepatitis B virus transgenic mice.
hepatitis B X
(13 times)
Gastroenterology
(7 times)
HBV (6 times)
HCC (6 times)
anti-HCV (1 time)
1992 Hepatitis B virus X protein is not central to the viral life cycle in vitro.
HBV-encoded X protein
(11 times)
Neoplasms
(4 times)
HBV (9 times)
HCC (9 times)
cccDNA (1 time)
2005 Integration of the hepatitis B virus X fragment in hepatocellular carcinoma and its effects on the expression of multiple molecules: a key to the cell cycle and apoptosis.
HBV x gene
(7 times)
Gastroenterology
(2 times)
HBV (5 times)
HCC (2 times)
AFB1 (1 time)
1997 Hepatitis B virus X-protein binds damaged DNA and sensitizes liver cells to ultraviolet irradiation.
Hepatitis B virus-encoded X protein
(7 times)
Gastroenterology
(2 times)
HCC (5 times)
4-HNE (1 time)
ATP (1 time)
2009 Proteomic analysis of differently expressed proteins in human hepatocellular carcinoma cell lines HepG2 with transfecting hepatitis B virus X gene.
10  HBV regulatory protein X
(4 times)
Biological Science Disciplines
(1 time)
HBV (4 times)
cccDNA (2 times)
DDB1 (1 time)
2015 Technical standards for hepatitis B virus X protein (HBx) research.
11  HBV protein x
(3 times)
Molecular Biology
(1 time)
HBV (3 times)
HCC (2 times)
AAV (1 time)
2006 Hepatocarcinogenesis in viral Hepatitis B infection: the role of HBx and p53.
12  HBV and its X protein
(2 times)
Neoplasms
(1 time)
HBV (2 times)
HCC (1 time)
2002 Brain metastasis from hepatocellular carcinoma associated with hepatitis B virus.
13  HBV counters this restriction by expressing the X protein
(2 times)
Virology
(2 times)
DDB1 (2 times)
HBV (2 times)
PHH (2 times)
2019 Hepatitis B Virus X Protein Function Requires Zinc Binding.
14  HBV-encoded X
(2 times)
Cell Biology
(1 time)
HBV (2 times)
HCC (2 times)
cccDNA (1 time)
2013 Hepatitis B virus X protein-induced aberrant epigenetic modifications contributing to human hepatocellular carcinoma pathogenesis.
15  hepatitis B protein X
(2 times)
Medicine
(1 time)
HBV (2 times)
FFAR2 (1 time)
GPR43 (1 time)
2019 Hepatitis B virus infection is not associated with fatty liver disease: Evidence from a cohort study and functional analysis.
16  hepatitis B virus-encoded X
(2 times)
Biochemistry
(1 time)
ALDH1 (1 time)
HCC (1 time)
miRNAs (1 time)
2009 Proteomic profiling identifies aberrant epigenetic modifications induced by hepatitis B virus X protein.
17  HBV accessory protein X
(1 time)
Gastroenterology
(1 time)
HBV (1 time)
2016 Identification of FDA-approved drugs that target hepatitis B virus transcription.
18  HBV also expresses active proteins such as X
(1 time)
Gastroenterology
(1 time)
HBV (1 time)
HCC (1 time)
2016 [Pathogenesis of hepatitis B virus-related hepatocellular carcinoma].
19  HBV DNA and expression vectors for the viral protein X
(1 time)
Virology
(1 time)
HBV (1 time)
HCC (1 time)
1995 In vitro transformation by hepatitis B virus DNA.
20  HBV encodes a small non-structural X protein
(1 time)
Natural Science Disciplines
(1 time)
APOBEC (1 time)
HBV (1 time)
HIV-1 (1 time)
2017 Hepatitis B virus X protein is capable of down-regulating protein level of host antiviral protein APOBEC3G.
21  HBV encodes a viral onco-protein, transactivator protein X
(1 time)
Cell Transformation, Neoplastic
(1 time)
ECM (1 time)
HBV (1 time)
HCC (1 time)
2018 Hepatitis transactivator protein X promotes extracellular matrix modification through HIF/LOX pathway in liver cancer.
22  HBV encodes seven viral proteins, including the nonstructural X
(1 time)
Virology
(1 time)
HBV (1 time)
2008 Hepatitis B virus HBx protein localizes to mitochondria in primary rat hepatocytes and modulates mitochondrial membrane potential.
23  HBV induces HIV-1 transcription through its X protein
(1 time)
Virology
(1 time)
HBV (1 time)
HIV-1 (1 time)
LTR (1 time)
2011 The X protein of HBV induces HIV-1 long terminal repeat transcription by enhancing the binding of C/EBPbeta and CREB1/2 regulatory proteins to the long terminal repeat of HIV-1.
24  HBV nonstructural protein, X protein
(1 time)
Science
(1 time)
AR (1 time)
HBV (1 time)
HCC (1 time)
2007 Hepatitis B virus X protein enhances androgen receptor-responsive gene expression depending on androgen level.
25  HBV proteins including the nonstructural X protein
(1 time)
Virology
(1 time)
HBV (1 time)
HCC (1 time)
2011 The hepatitis B virus HBx protein modulates cell cycle regulatory proteins in cultured primary human hepatocytes.
26  HBV RNAs and that encoding the X protein
(1 time)
Biochemistry
(1 time)
ccDNA (1 time)
EGFR (1 time)
HBV (1 time)
2020 HBx increases EGFR expression by inhibiting miR129-5p function.
27  HBV stimulates by its X protein
(1 time)
Cell Biology
(1 time)
G6PD (1 time)
HBV (1 time)
2015 Hepatitis B virus stimulates G6PD expression through HBx-mediated Nrf2 activation.
28  HBV X supermolecule
(1 time)
Communicable Diseases
(1 time)
HBV (1 time)
HCC (1 time)
2019 Molecular mechanistic insight of hepatitis B virus mediated hepatocellular carcinoma.
29  HBV's so-called X gene product
(1 time)
Biochemistry
(1 time)
NAFLD (1 time)
2008 Viral hepatitis and fatty liver disease: how an unwelcome guest makes pate of the host.
30  HBV-encoded regulatory protein X
(1 time)
Allergy and Immunology
(1 time)
HBV (1 time)
IFN (1 time)
ISG (1 time)
2019 Type III interferon-induced CBFbeta inhibits HBV replication by hijacking HBx.
31  HBV-encoded X antigen
(1 time)
Pathology
(1 time)
GAS2 (1 time)
HBV (1 time)
HCC (1 time)
2015 Truncated HBx-dependent silencing of GAS2 promotes hepatocarcinogenesis through deregulation of cell cycle, senescence and p53-mediated apoptosis.
32  HBV-mediated pathogenesis is only partially understood, but X protein
(1 time)
Biochemistry
(1 time)
HBV (1 time)
2014 Quantitative proteomic analysis of exosome protein content changes induced by hepatitis B virus in Huh-7 cells using SILAC labeling and LC-MS/MS.
33  HBx encodes the X protein
(1 time)
Molecular Biology
(1 time)
ATF (1 time)
HBV (1 time)
HCC (1 time)
2013 Creation of a six-fingered artificial transcription factor that represses the hepatitis B virus HBx gene integrated into a human hepatocellular carcinoma cell line.
34  hepatitis B virus infection, and that viral X protein
(1 time)
Gastroenterology
(1 time)
iNOS (1 time)
NF-kappaB (1 time)
2001 Hepatitis B virus X protein transactivates inducible nitric oxide synthase gene promoter through the proximal nuclear factor kappaB-binding site: evidence that cytoplasmic location of X protein is essential for gene transactivation.
35  Hepatitis B virus x gene product
(1 time)
Biochemistry
(1 time)
CsA (1 time)
2003 Activation of calcium signaling by hepatitis B virus-X protein in liver cells.