| 1 |
hypoxia-inducible factor-1alpha
(5565 times)
|
Neoplasms
(1003 times)
|
VEGF (1144 times)
ROS (243 times)
EMT (149 times)
|
1997 Abnormal angiogenesis and responses to glucose and oxygen deprivation in mice lacking the protein ARNT.
|
| 2 |
hypoxia-inducible transcription factor-1alpha
(75 times)
|
Neoplasms
(13 times)
|
VEGF (12 times)
CRC (3 times)
IL-6 (3 times)
|
2001 Imaging of whole tumor cut sections using a novel scanning beam confocal fluorescence MACROscope.
|
| 3 |
hypoxia-inducible factor 1 subunit alpha
(28 times)
|
Biochemistry
(5 times)
|
mTOR (3 times)
VEGF (3 times)
DR (2 times)
|
2002 Disruption of oxygen homeostasis underlies congenital Chuvash polycythemia.
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| 4 |
HIF-1 is formed by a regulatory alpha-subunit
(2 times)
|
Toxicology
(1 time)
|
HIF-1 (2 times)
WSSV (2 times)
LDH (1 time)
|
2018 Regulation of lactate dehydrogenase in response to WSSV infection in the shrimp Litopenaeus vannamei.
|
| 5 |
hypoxia-inhibitory factor-1alpha
(2 times)
|
Metabolism
(1 time)
|
EdU (1 time)
HCC (1 time)
HFpEF (1 time)
|
2019 Hypoxia-inducible factor 1-alpha (HIF-1alpha) as a factor mediating the relationship between obesity and heart failure with preserved ejection fraction.
|
| 6 |
heat shock-induced factor-1alpha
(1 time)
|
Neoplasms
(1 time)
|
CSCs (1 time)
ERK (1 time)
HCC (1 time)
|
2016 ELK3 promotes the migration and invasion of liver cancer stem cells by targeting HIF-1alpha.
|
| 7 |
HIF-1 alpha subunit
(1 time)
|
Dentistry
(1 time)
|
CA-HIF1A (1 time)
DMOG (1 time)
HIF-1 (1 time)
|
2018 Activation of hypoxia-inducible factor1 attenuates periapical inflammation and bone loss.
|
| 8 |
HIF-1 consists of a heterodimeric oxygen-regulated alpha subunit
(1 time)
|
Biology
(1 time)
|
ARNT (1 time)
DPBS (1 time)
HIF-1 (1 time)
|
2018 Co-immunoprecipitation Assay Using Endogenous Nuclear Proteins from Cells Cultured Under Hypoxic Conditions.
|
| 9 |
HIF-1 is composed of an oxygen-regulated alpha subunit
(1 time)
|
Molecular Biology
(1 time)
|
bHLH (1 time)
HIF-1 (1 time)
ODDD (1 time)
|
2010 Molecular characterization of hypoxia and hypoxia-inducible factor 1 alpha (HIF-1alpha) from Taiwan voles (Microtus kikuchii).
|
| 10 |
HIF-1 is dictated primarily by its alpha subunit
(1 time)
|
|
HIF-1 (1 time)
PHDs (1 time)
SIAH2 (1 time)
|
2021 Regulation of the SIAH2-HIF-1 Axis by Protein Kinases and Its Implication in Cancer Therapy.
|
| 11 |
HIF-1 oxygen-dependent alpha subunit
(1 time)
|
Cell Biology
(1 time)
|
BBB (1 time)
HIF-1 (1 time)
TJ (1 time)
|
2014 Hypoxia selectively disrupts brain microvascular endothelial tight junction complexes through a hypoxia-inducible factor-1 (HIF-1) dependent mechanism.
|
| 12 |
HIF-1 requires binding of its alpha-subunit
(1 time)
|
Chemistry
(1 time)
|
HIF-1 (1 time)
|
2015 Structural Elucidation and Synthesis of Eudistidine A: An Unusual Polycyclic Marine Alkaloid that Blocks Interaction of the Protein Binding Domains of p300 and HIF-1alpha.
|
| 13 |
hypoxia factor-1alpha
(1 time)
|
Neoplasms
(1 time)
|
NSCLC (1 time)
ROIs (1 time)
VEGF (1 time)
|
2009 [Correlations of 99 Tc m-HL91 SPECT hypoxia imaging with HIF-1alpha and VEGF expression in non-small cell lung cancer].
|
| 14 |
hypoxia inducible growth factor-1alpha
(1 time)
|
Pharmacology
(1 time)
|
ACEI (1 time)
DEN (1 time)
HCC (1 time)
|
2013 Targeting different angiogenic pathways with combination of curcumin, leflunomide and perindopril inhibits diethylnitrosamine-induced hepatocellular carcinoma in mice.
|
| 15 |
hypoxia response factor-1 alpha
(1 time)
|
Biochemistry
(1 time)
|
IGF-1R (1 time)
mTOR (1 time)
|
2017 Regulation of the insulin-Akt signaling pathway and glycolysis during dehydration stress in the African clawed frog Xenopus laevis.
|
| 16 |
hypoxia transcription factor-1 alpha
(1 time)
|
Neurosurgery
(1 time)
|
CHAD (1 time)
NP (1 time)
qRT-PCR (1 time)
|
2018 Are Specific Gene Expressions of Extracellular Matrix and Nucleus Pulposus Affected by Primary Cell Cultures Prepared from Intact or Degenerative Intervertebral Disc Tissues?
|
| 17 |
hypoxia-inducible 1alpha transcription factor
(1 time)
|
Neoplasms
(1 time)
|
EMT (1 time)
MET (1 time)
|
2013 The paradox of E-cadherin: role in response to hypoxia in the tumor microenvironment and regulation of energy metabolism.
|
| 18 |
hypoxia-sensitive inducible factor 1alpha
(1 time)
|
Cell Biology
(1 time)
|
sFlt-1 (1 time)
TRPV6 (1 time)
|
2012 Differential expression of calcium transport channels in placenta primary cells and tissues derived from preeclamptic placenta.
|
| 19 |
hypoxic conditions, treatment of Tca8113 cells with siRNA
(1 time)
|
Medicine
(1 time)
|
RT (1 time)
siRNA (1 time)
|
2009 Effects of hypoxia inducible factor-1alpha (HIF-1alpha) on the growth & adhesion in tongue squamous cell carcinoma cells.
|
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