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Abbreviation: HaCaT
Appearance Frequency: 1037 time(s)
Long forms: 62

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Long Form No. Long Form Research Area Co-occurring Abbreviation PubMed/MEDLINE Info. (Year, Title)
human keratinocytes
(943 times)
Pharmacology
(108 times)
ROS (108 times)
UVB (34 times)
AD (26 times)
1990 c-Ha-ras oncogene expression in immortalized human keratinocytes (HaCaT) alters growth potential in vivo but lacks correlation with malignancy.
human epithelial cells
(10 times)
Dentistry
(2 times)
cDMEM (1 time)
DIM (1 time)
EMSA (1 time)
2001 Regulation of the human transforming growth factor beta type II receptor gene promoter by novel Sp1 sites.
human adult low calcium temperature
(9 times)
Pharmacology
(2 times)
14DAP (1 time)
ANDRO (1 time)
DCFH-DA (1 time)
2004 Functional characterization of sodium- and chloride-dependent taurine transport in human keratinocytes.
human immortalized epidermal cells
(5 times)
Skin Diseases
(1 time)
FLG (1 time)
HD (1 time)
IL-17 (1 time)
2020 Adenovirus-Mediated LAMA3 Transduction Enhances Hemidesmosome Formation and Periodontal Reattachment during Wound Healing.
human cell lines-keratinocytes
(4 times)
Chemistry
(2 times)
CAT (1 time)
PCD (1 time)
PS (1 time)
2006 Effects of sodium arsenite on catalase activity, gene and protein expression in HaCaT cells.
human epithelial keratinocyte
(4 times)
Chemistry Techniques, Analytical
(2 times)
SSR (2 times)
AB (1 time)
2010 Three dimensional collagen gels as a cell culture matrix for the study of live cells by Raman spectroscopy.
human-derived keratinocytes
(3 times)
Nanotechnology
(1 time)
AFM (1 time)
CELC (1 time)
DNA (1 time)
2013 Phototoxicity of zinc oxide nanoparticles in HaCaT keratinocytes-generation of oxidative DNA damage during UVA and visible light irradiation.
healing against human keratinocytes
(2 times)
Biochemistry
(1 time)
HSF (1 time)
2017 OM-LV20, a novel peptide from odorous frog skin, accelerates wound healing in vitro and in vivo.
human cancer cell lines, which is contrary to normal
(2 times)
Biology
(2 times)
--- 2020 Cytotoxicity Evaluation of Novel bis(2-aminoethyl)amine Derivatives.
10  human epidermal immortal keratinocytes
(2 times)
Nanotechnology
(1 time)
DOC-LS (1 time)
2014 Evaluation of transdermal salidroside delivery using niosomes via in vitro cellular uptake.
11  human immortalized non-malignant keratinocytes
(2 times)
Medicine
(1 time)
DMMB (1 time)
MTX (1 time)
RPE (1 time)
2019 Self-assembling water-soluble polymethacrylate-MTX conjugates: The significance of macromolecules architecture on drug conjugation efficiency, the final shape of particles, and drug release.
12  checked against cell lines by using Keratinocytes cell lines
(1 time)
Natural Science Disciplines
(1 time)
--- 2019 Ampicillin Silver Nanoformulations against Multidrug resistant bacteria.
13  HaCaT Keratinocyte
(1 time)
Biochemistry
(1 time)
EMT (1 time)
SASP (1 time)
2017 Paeonol attenuates aging MRC-5 cells and inhibits epithelial-mesenchymal transition of premalignant HaCaT cells induced by aging MRC-5 cell-conditioned medium.
14  hair growth-associated gene expression in dermal papilla cells and keratinocytes
(1 time)
Complementary Therapies
(1 time)
CTE (1 time)
2013 Hair growth-promoting effect of Carthamus tinctorius floret extract.
15  HARVs promoted aggregation of keratinocytes
(1 time)
Cell Biology
(1 time)
HARVs (1 time)
2009 Generation of a tumor spheroid in a microgravity environment as a 3D model of melanoma.
16  HAT and PAR-2 mRNA, and immortalized keratinocytes
(1 time)
Dermatology
(1 time)
BrdU (1 time)
HAT (1 time)
PAR (1 time)
2004 Human airway trypsin-like protease induces PAR-2-mediated IL-8 release in psoriasis vulgaris.
17  have a distinctive and iodine-dependent reaction to ionizing radiation, keratinocytes
(1 time)
Environmental Health
(1 time)
LINAC (1 time)
2016 Influence of iodine supply on the radiation-induced DNA-fragmentation.
18  have cultured normal epithelial cells
(1 time)
Ophthalmology
(1 time)
FRMMs (1 time)
2019 Sensitive detection of the concentrations for normal epithelial cells based on Fano resonance metamaterial biosensors in terahertz range.
19  healing rate in keratinocyte
(1 time)
Pharmacology
(1 time)
--- 2015 Modulating prime molecular expressions and in vitro wound healing rate in keratinocyte (HaCaT) population under characteristic honey dilutions.
20  healing used keratinocytes
(1 time)
ELF (1 time)
EMFs (1 time)
LF (1 time)
2015 Experimental model for ELF-EMF exposure: Concern for human health.
21  healthy cells, such as immortalized human epithelial
(1 time)
Chemistry
(1 time)
CPT (1 time)
PAA (1 time)
PVA (1 time)
2020 Nanofibrous silica microparticles/polymer hybrid aerogels for sustained delivery of poorly water-soluble camptothecin.
22  healthy individuals on keratinocytes
(1 time)
Dermatology
(1 time)
AE (1 time)
PBMC (1 time)
1995 Cytokine-mediated effects of peripheral blood mononuclear cells from patients with atopic eczema on keratinocytes (HaCaT) in a new coculture system.
23  healthy keratinocyte cells
(1 time)
Biochemistry
(1 time)
--- 2022 Chemical Composition and Tyrosinase Inhibitory Activities of Fatty Acids Obtained from Heterotrophic Microalgae, S. limacinum and C. cohnii.
24  heparin and human keratinocyte
(1 time)
Biochemistry
(1 time)
GAGs (1 time)
HPV (1 time)
VLPs (1 time)
1999 The L1 major capsid protein of human papillomavirus type 11 recombinant virus-like particles interacts with heparin and cell-surface glycosaminoglycans on human keratinocytes.
25  high temperature keratinocyte
(1 time)
Biophysics
(1 time)
--- 2013 The biological impact of concurrent exposure to metallic nanoparticles and a static magnetic field.
26  high-resolution microscopy of intact keratinocyte
(1 time)
Physiological Phenomena
(1 time)
TEM (1 time)
TRPC (1 time)
2023 TRPC1 channel clustering during store-operated Ca2+ entry in keratinocytes.
27  high-temperature keratinocytes cell line
(1 time)
Biotechnology
(1 time)
CsA (1 time)
DUSPs (1 time)
ELISA (1 time)
2023 Variances in the Expression Profile of DUSP1-7 and miRNAs Regulating Their Expression in the Hacat Line Under LPS and Cyclosporine A.
28  higher cell viability and improved metabolic activity in both keratinocytes
(1 time)
UV (1 time)
2021 Protective Effects of Linearthin and Other Chalcone Derivatives from Aspalathus linearis (Rooibos) against UVB Induced Oxidative Stress and Toxicity in Human Skin Cells.
29  higher dependence and keratinocytes
(1 time)
Biology
(1 time)
LDL (1 time)
2015 The effect of LDL particles on the behaviour of epithelial noncancer and cancer cell lines after in vitro induced injury.
30  highly differentiating keratinocyte cell line
(1 time)
Neoplasms
(1 time)
Cx (1 time)
GJIC (1 time)
1994 Expression and function of connexin in normal and transformed human keratinocytes in culture.
31  histamine-induced human keratinocytes cell
(1 time)
Complementary Therapies
(1 time)
ELISA (1 time)
IL (1 time)
MAPK (1 time)
2018 Curcumin derivative, 2,6-bis(2-fluorobenzylidene)cyclohexanone (MS65) inhibits interleukin-6 production through suppression of NF-kappaB and MAPK pathways in histamine-induced human keratinocytes cell (HaCaT).
32  HNSCC, we generated gene expression signatures using immortalized keratinocytes
(1 time)
Genetics
(1 time)
CoGAPS (1 time)
EGFR (1 time)
HNSCC (1 time)
2012 Gene expression signatures modulated by epidermal growth factor receptor activation and their relationship to cetuximab resistance in head and neck squamous cell carcinoma.
33  honey-alginate and alginate matrices on re-epithelialization in keratinocyte
(1 time)
Biomimetics
(1 time)
--- 2013 Assessment of molecular events during in vitro re-epithelialization under honey-alginate matrix ambience.
34  human adult epidermal cells
(1 time)
Chemistry
(1 time)
CTGF (1 time)
DFUs (1 time)
EE (1 time)
2021 Sulfated alginate/polycaprolactone double-emulsion nanoparticles for enhanced delivery of heparin-binding growth factors in wound healing applications.
35  human adult low-calcium elevated temperature
(1 time)
Antineoplastic Agents
(1 time)
HDF (1 time)
2015 Cytotoxic effect and mechanism inducing cell death of alpha-mangostin liposomes in various human carcinoma and normal cells.
36  human calcium- and temperature-dependent
(1 time)
Medicine
(1 time)
DIDS (1 time)
TEA (1 time)
2004 Mitochondrial membrane potential (DeltaPsi) and Ca(2+)-induced differentiation in HaCaT keratinocytes.
37  human cell lines established in culture, immortalized skin keratinocyte
(1 time)
Dermatology
(1 time)
qRT-PCR (1 time)
2016 Expression of heparanase in basal cell carcinoma and squamous cell carcinoma.
38  human epithelial cell
(1 time)
Biology
(1 time)
--- 2006 ELF non ionizing radiation changes the distribution of the inner chemical functional groups in human epithelial cell (HaCaT) culture.
39  human epithelium-derived cells, immortalized keratinocytes
(1 time)
Dose-Response Relationship, Drug
(1 time)
MMP (1 time)
2019 Effects of Dose Rate on the Reproductive Cell Death and Early Mitochondrial Membrane Potential in Different Human Epithelium-Derived Cells Exposed to Gamma Rays.
40  human keratinocyte cell line of skin tissue
(1 time)
Carbohydrates
(1 time)
GC-MS (1 time)
2016 Effect of fucoidan from Turbinaria conoides on human lung adenocarcinoma epithelial (A549) cells.
41  human keratinocyte cell line with complete epidermal differentiation capacity
(1 time)
Dermatology
(1 time)
CGP (1 time)
1991 High density of beta 2-adrenoceptors in a human keratinocyte cell line with complete epidermal differentiation capacity (HaCaT).
42  Human keratinocyte cultures
(1 time)
Allergy and Immunology
(1 time)
AMPs (1 time)
DENV (1 time)
IFITM3 (1 time)
2018 Human keratinocyte cultures (HaCaT) can be infected by DENV, triggering innate immune responses that include IFNlamda and LL37.
43  human keratinocyte immortal cells
(1 time)
Pharmacology
(1 time)
--- 2016 A novel steroid and cytotoxic constituents from Dioscorea membranacea Pierre against hepatocellular carcinoma and cholangiocarcinoma cells.
44  human keratinocytes and precancerous
(1 time)
Dermatology
(1 time)
PI3K (1 time)
2010 Inhibition of Akt signaling by exclusion from lipid rafts in normal and transformed epidermal keratinocytes.
45  human keratinocytes, immortalized keratinocytes
(1 time)
Dermatology
(1 time)
--- 2002 Differential responses of S100A2 to oxidative stress and increased intracellular calcium in normal, immortalized, and malignant human keratinocytes.
46  human non-malignant immortalized keratinocytes
(1 time)
Biology
(1 time)
ERs (1 time)
HFF (1 time)
siRNAs (1 time)
2021 Silibinin treatment protects human skin cells from UVB injury through upregulation of estrogen receptors.
47  human non-tumorigenic keratinocytes
(1 time)
Botany
(1 time)
--- 2017 Metabolite Profile and Antiproliferative Effects in HaCaT Cells of a Salix reticulata Extract.
48  human normal immortalized epithelial cell lines
(1 time)
Neoplasms
(1 time)
CC (1 time)
EMT (1 time)
FIGO (1 time)
2020 miR-4429 Regulates the Proliferation, Migration, Invasion, and Epithelial-Mesenchymal Transition of Cervical Cancer by Targeting FOXM1.
49  human precancerous keratinocytes
(1 time)
Medicine
(1 time)
PP2 (1 time)
2011 Barium promotes anchorage-independent growth and invasion of human HaCaT keratinocytes via activation of c-SRC kinase.
50  human skin cell lines were employed: normal keratinocytes
(1 time)
Biology
(1 time)
ALS (1 time)
bio (1 time)
CAPB (1 time)
2021 Soapwort (Saponaria officinalis L.) Extract vs. Synthetic Surfactants-Effect on Skin-Mimetic Models.
51  human skin cells representing various skin layers, namely keratinocytes
(1 time)
Biology
(1 time)
ChEO (1 time)
2022 Assessment of safety and health-benefits of Citrus hystrix DC. peel essential oil, with regard to its bioactive constituents in an in vitro model of physiological and pathological skin conditions.
52  human skin equivalent using a spontaneously transformed keratinocyte cell line
(1 time)
Dermatology
(1 time)
--- 1999 Reconstruction of a human skin equivalent using a spontaneously transformed keratinocyte cell line (HaCaT).
53  human skin, represented by a keratinocytes cell line
(1 time)
Biochemistry
(1 time)
ERG (1 time)
ovo (1 time)
2022 First evidence of dermo-protective activity of marine sulfur-containing histidine compounds.
54  Human spontaneously immortalized keratinocytes
(1 time)
Pharmacology
(1 time)
MMP (1 time)
2013 Low zoledronate concentrations stimulate human keratinocyte proliferation.
55  hurpin transcripts are more abundant in immortalized keratinocytes
(1 time)
Molecular Biology
(1 time)
ov-serpins (1 time)
SCCA1 (1 time)
SCCA2 (1 time)
1999 Cloning and characterization of hurpin (protease inhibitor 13): A new skin-specific, UV-repressible serine proteinase inhibitor of the ovalbumin serpin family.
56  hydrogel using epidermal keratinocyte
(1 time)
Drug Therapy
(1 time)
--- 2022 Honey-based Silver Sulfadiazine Microsponge-Loaded Hydrogel: In vitro and In vivo Evaluation for Burn Wound Healing.
57  hyper-proliferative keratinocyte cell line
(1 time)
Chemistry
(1 time)
CLSM (1 time)
MTX (1 time)
NLCs (1 time)
2016 Nanostructured lipid carrier mediates effective delivery of methotrexate to induce apoptosis of rheumatoid arthritis via NF-kappaB and FOXO1.
58  hyperproliferant keratinocytes
(1 time)
Chemistry
(1 time)
--- 2015 Effects of topical corticosteroids on cell proliferation, cell cycle progression and apoptosis: in vitro comparison on HaCaT.
59  hyperproliferation of keratinocyte
(1 time)
Polymers
(1 time)
HA-pNIPAM (1 time)
2021 Self-Assembled Thermoresponsive Nanogel from Grafted Hyaluronic Acid as a Biocompatible Delivery Platform for Curcumin with Enhanced Drug Loading and Biological Activities.
60  hypothesis of a trans-differentiation process from an epidermal
(1 time)
Cell Biology
(1 time)
--- 1993 "Trans-differentiation" from epidermal to mesenchymal/myogenic phenotype is associated with a drastic change in cell-cell and cell-matrix adhesion molecules.
61  hypoxia damages to keratinocytes
(1 time)
Allergy and Immunology
(1 time)
--- 2015 Fucosterol protects cobalt chloride induced inflammation by the inhibition of hypoxia-inducible factor through PI3K/Akt pathway.
62  Superoxide-hydrogen peroxide imbalance differentially modulates the keratinocytes cell line
(1 time)
Molecular Biology
(1 time)
NO (1 time)
S-HP (1 time)
2019 Superoxide-hydrogen peroxide imbalance differentially modulates the keratinocytes cell line (HaCaT) oxidative metabolism via Keap1-Nrf2 redox signaling pathway.