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Abbreviation: IC50
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Long Form No. Long Form Research Area Co-occurring Abbreviation PubMed/MEDLINE Info. (Year, Title)
inhibitory concentration 50
(187 times)
Pharmacology
(31 times)
RT-PCR (5 times)
5-FU (4 times)
CC50 (4 times)
1983 A simple radiometric in vitro assay for acetylcholinesterase inhibitors.
concentration causing 50% inhibition
(23 times)
Physiology
(4 times)
12-HETE (1 time)
12-HPETE (1 time)
ABEC (1 time)
1984 Platelet receptor recognition site on human fibrinogen. Synthesis and structure-function relationship of peptides corresponding to the carboxy-terminal segment of the gamma chain.
its concentrations for 50% inhibition
(15 times)
Biochemistry
(5 times)
5-HETE (2 times)
HLM (2 times)
5,12-diHETE (1 time)
1982 Selective inhibition of platelet lipoxygenase by esculetin.
inhibited cell growth by 50
(11 times)
Neoplasms
(4 times)
5-aza (1 time)
5-FU (1 time)
AR (1 time)
1984 Galactosyltransferase activity and cell growth: uridine diphosphate (UDP)galactose inhibition of murine leukemic L1210 cells.
inhibiting 50% of enzyme activity
(9 times)
Toxicology
(4 times)
CA (2 times)
COX (2 times)
4-AP (1 time)
1994 Dibasic (amidinoaryl)propanoic acid derivatives as novel blood coagulation factor Xa inhibitors.
inhibit cell proliferation by 50
(8 times)
Neoplasms
(4 times)
5-FU (2 times)
TS (2 times)
DEX (1 time)
1989 Enhanced sensitivity of the rat hepatoma cell to the daunorubicin analogue 4-demethoxydaunorubicin associated with induction of DNA damage.
induce 50% inhibition
(6 times)
Drug Therapy
(2 times)
ADP (1 time)
CDCA (1 time)
CI (1 time)
1987 Inhibition by amiloride of contractile elements in smooth muscle of guinea pig taenia cecum and chicken gizzard.
inhibit the ATPase activity by 50
(6 times)
Genetics, Medical
(1 time)
DHFR (1 time)
MC (1 time)
MTX (1 time)
1986 Thiopurine methyltransferase: structure-activity relationships for benzoic acid inhibitors and thiophenol substrates.
incorporation into DNA by 50
(4 times)
Pharmacology
(2 times)
--- 2001 Aromatic extended bisamidines: synthesis, inhibition of topoisomerases, and anticancer cytotoxicity in vitro.
10  inhibit 50% of the collagenase activity
(4 times)
Dentistry
(2 times)
BMVC (1 time)
GCF (1 time)
LJP (1 time)
1992 Tetracycline inhibition identifies the cellular origin of interstitial collagenases in human periodontal diseases in vivo.
11  induced 50% growth inhibition
(3 times)
Neoplasms
(1 time)
FCS (1 time)
G. lamblia (1 time)
HPLC (1 time)
1995 Effects of suramin on human lung cancer cell lines.
12  inhibit 50% of ACE enzymatic activity
(3 times)
Pharmacology
(2 times)
ACE (1 time)
PAF (1 time)
PDE (1 time)
1988 Relative inhibitory potency and plasma drug levels of angiotensin converting enzyme inhibitors in the rat.
13  inhibit the growth of HT-29 cells by 50
(3 times)
Neoplasms
(2 times)
BCRP (1 time)
EHNA (1 time)
MAIQ (1 time)
1990 Effect of ribonucleotide reductase inhibitors on the growth of human colon carcinoma HT-29 cells in culture.
14  inhibit the proliferation of cells by 50
(3 times)
Neoplasms
(2 times)
CDDP (1 time)
PNS (1 time)
1993 In vitro antitumor activity of a new platinum complex, DWA2114R against human tumor cell lines.
15  inhibited 50% cell viability
(3 times)
Mycotoxins
(1 time)
ALDH1 (1 time)
ChIP (1 time)
OSCC (1 time)
2009 Trichothecene-induced cytotoxicity on human cell lines.
16  inhibited 50% of the cell growth
(3 times)
Communicable Diseases
(1 time)
EP (1 time)
HIV (1 time)
IC 90 (1 time)
1993 In vitro antiviral activity of didanosine compared with that of other dideoxynucleoside analogs against laboratory strains and clinical isolates of human immunodeficiency virus.
17  inhibiting concentration for 50% block
(3 times)
Neurology
(2 times)
AFM (1 time)
BAC (1 time)
Cts-g-PAAm (1 time)
1990 Pharmacological and Biochemical Properties of Nicotinic Receptors from Chick Retina.
18  inhibitory concentration of 50% of free radicals
(3 times)
Hematologic Agents
(2 times)
STZ (3 times)
A.E.P.F.A.S (1 time)
APAE (1 time)
2017 Potent antihyperglycemic and hypoglycemic effect of Tamarix articulata Vahl. in normal and streptozotocin-induced diabetic rats.
19  Inhibitory drug concentrations in 50% of cells
(3 times)
Pharmacognosy
(1 time)
HL-PST (1 time)
NSAIDs (1 time)
1991 Comparison of cytotoxicity in heart cells and tumor cells exposed to DNA intercalating agents in vitro.
20  Acacetin caused 50% growth inhibition
(2 times)
Cell Biology
(1 time)
PARP (2 times)
AIF (1 time)
MAPK (1 time)
2007 Acacetin-induced apoptosis of human breast cancer MCF-7 cells involves caspase cascade, mitochondria-mediated death signaling and SAPK/JNK1/2-c-Jun activation.
21  IC50 value of 30.75 mug/ml compared to ascorbic acid
(2 times)
Pharmacology
(2 times)
EFA (1 time)
NO (1 time)
2013 Antinociceptive and antioxidant potential of the crude ethanol extract of the leaves of Ageratum conyzoides grown in Bangladesh.
22  incorporation by 50
(2 times)
Virology
(1 time)
CC50 (1 time)
EICAR (1 time)
IMP dehydrogenase (1 time)
1996 Inhibitors of infectious pancreatic necrosis virus (IPNV) replication.
23  increased 50% inhibitory concentration
(2 times)
Pediatrics
(1 time)
17-AAG (1 time)
ALL (1 time)
Hz (1 time)
2005 Effects of 17-allylamino-17-demethoxygeldanamycin (17-AAG) on pediatric acute lymphoblastic leukemia (ALL) with respect to Bcr-Abl status and imatinib mesylate sensitivity.
24  induce 50% of the maximal relaxation
(2 times)
Pharmacology
(1 time)
EOPB (1 time)
NMDA (1 time)
WKY (1 time)
1995 Inhibition by propofol (2,6 di-isopropylphenol) of the N-methyl-D-aspartate subtype of glutamate receptor in cultured hippocampal neurones.
25  induces a 50% reduction of viability
(2 times)
Allergy and Immunology
(2 times)
PSMA (2 times)
2006 A recombinant PSMA-specific single-chain immunotoxin has potent and selective toxicity against prostate cancer cells.
26  inhibit 50% of the colony formation
(2 times)
Antineoplastic Agents
(1 time)
BM (1 time)
DXR (1 time)
1992 Reduced cardiotoxicity and increased cytotoxicity in a novel anthracycline analogue, 4'-amino-3'-hydroxy-doxorubicin.
27  inhibit 50% of the parasitic growth
(2 times)
Parasitology
(1 time)
ABTS (1 time)
FRAP (1 time)
ORAC (1 time)
2014 Activity of olive leaf extracts against the promastigote stage of Leishmania species and their correlation with the antioxidant activity.
28  inhibit activity by 50
(2 times)
Molecular Biology
(1 time)
AChE (1 time)
PDE (1 time)
1989 Inotropic responses to cyclic nucleotide phosphodiesterase inhibitors in immature and adult rabbit myocardium.
29  inhibit colour development by 50
(2 times)
Nutritional Sciences
(1 time)
DON (1 time)
ELISA (1 time)
LC (1 time)
1994 Quantitation and stability of fumonisins B1 and B2 in milk.
30  inhibited colony formation by 50
(2 times)
Antineoplastic Agents
(1 time)
9-AC (1 time)
CAM (1 time)
CFU-GM (1 time)
1988 Inhibition of hemopoiesis in murine marrow cell cultures by recombinant murine tumor necrosis factor alpha: evidence for long-term effects on stromal cells.
31  inhibiting cell survival by 50
(2 times)
Neoplasms
(1 time)
FCS (1 time)
GST (1 time)
Pt (1 time)
1994 Effect of ultrafilterable platinum concentration on cisplatin and carboplatin cytotoxicity in human tumor and bone marrow cells in vitro.
32  inhibition concentration of 50% cell growth
(2 times)
Neoplasms
(2 times)
LRP (1 time)
2010 [Effect of Bufalin on proliferation and apoptosis of human non-small cell lung cancer A549 cell].
33  inhibition of the 50% of AChE activity
(2 times)
Veterinary Medicine
(1 time)
CPF (1 time)
DFU (1 time)
NSAID (1 time)
2001 In vitro effects of cyclooxygenase inhibitors in whole blood of horses, dogs, and cats.
34  inhibitory concentration of gefitinib yielding 50% cell viability
(2 times)
Neoplasms
(2 times)
NSCLC (2 times)
miR-630 (1 time)
TKI (1 time)
2018 PD-L1 confers resistance to EGFR mutation-independent tyrosine kinase inhibitors in non-small cell lung cancer via upregulation of YAP1 expression.
35  into pseudo-Hill plots and the concentrations at 50% inhibition
(2 times)
Chemistry Techniques, Analytical
(2 times)
FP (2 times)
ER (1 time)
hrER-beta (1 time)
2003 Study on interactions of endocrine disruptors with estrogen receptor-beta using fluorescence polarization.
36  steroid causing 50% inhibition
(2 times)
Allergy and Immunology
(1 time)
HD (1 time)
HECM (1 time)
IL-2R (1 time)
1995 Comparative study of the effects of different glucocorticosteroids on eosinophil survival primed by cultured epithelial cell supernatants obtained from nasal mucosa and nasal polyps.
37  (ADP)-induced platelet aggregation with 50% inhibition
(1 time)
Hematology
(1 time)
ADP (1 time)
1992 Antithrombotic properties of L-cysteine, N-(mercaptoacetyl)-D-Tyr-Arg-Gly-Asp-sulfoxide (G4120) in a hamster platelet-rich femoral vein thrombosis model.
38  adrenaline-induced arrhythmia by 50
(1 time)
Pharmacology
(1 time)
--- 1993 Effects of gallopamil, a Ca2+ channel blocker in models of ventricular arrhythmia in dogs.
39  anti-influenza virus type A activity with 50% inhibition
(1 time)
Complementary Therapies
(1 time)
--- 2006 Phytochemical screening and antiviral activity of some medicinal plants from the island Soqotra.
40  chlorpyrifos-inhibitory concentration 50
(1 time)
Insects
(1 time)
AChE (1 time)
CarE (1 time)
CAT (1 time)
2017 Effects of chlorpyrifos on enzymatic systems of Cydia pomonella (Lepidoptera: Tortricidae) adults.
41  collagen-induced platelet aggregation by 50
(1 time)
Chemistry, Clinical
(1 time)
--- 2007 Utility of PFA-100 closure time vs. optical aggregometry in assessing the efficacy of platelet membrane glycoprotein IIb/IIIa antagonists in vitro.
42  concentration causing 50% inhibition of the initial rate of glucuronidation
(1 time)
Neoplasms
(1 time)
--- 1993 Bile acid inhibition of xenobiotic-metabolizing enzymes is a factor in the mechanism of colon carcinogenesis: tests of aspects of the concept with glucuronosyltransferase.
43  concentration causing 50% reduction of the signal intensity
(1 time)
Allergy and Immunology
(1 time)
DMPO (1 time)
OZ (1 time)
PMA (1 time)
1989 [Influences of anti-allergic drugs on superoxide generation from the hypoxanthine-xanthine oxidase system or polymorphonuclear leukocytes].
44  concentrations causing 50% inhibition of in vitro growth of Plasmodium berghei
(1 time)
Biology
(1 time)
--- 2014 In vitro antiplasmodial activity, cytotoxicity and chemical profiles of sponge species of Cuban coasts.
45  concentrations causing 50% reproductive inhibition
(1 time)
Chemistry
(1 time)
SSDs (1 time)
2016 Increasing uranium exposure durations to the aquatic snail Amerianna cumingi does not result in lower toxicity estimates.
46  copper-induced lipid hydroperoxidation of LDL by 50
(1 time)
Pharmacology
(1 time)
LDL (1 time)
1996 Inhibition of lipid hydroperoxidation of low density lipoprotein by the Ca(2+)-channel and alpha 1-adrenoceptor antagonist monatepil maleate.
47  experiments causing 50% cell growth inhibition
(1 time)
Neoplasms
(1 time)
MTT (1 time)
2008 Cytotoxicity of a series of ferrocene-containing beta-diketones.
48  FHV-1-induced plaque formation by 50
(1 time)
Ophthalmology
(1 time)
--- 2014 In vitro cytotoxicity and antiviral efficacy against feline herpesvirus type 1 of famciclovir and its metabolites.
49  HSV-2-infected cells, with a 50% neutralizing dilution
(1 time)
Anti-Bacterial Agents
(1 time)
HSV-2 (1 time)
2015 Antiviral activity of a single-domain antibody immunotoxin binding to glycoprotein D of herpes simplex virus 2.
50  hydrophilic compound; 50% inhibition
(1 time)
Botany
(1 time)
--- 1984 Identification of calmodulin in the green alga Mougeotia and its possible function in chloroplast reorientational movement.
51  I-DOX, and the concentration of drug that inhibited by 50
(1 time)
Neoplasms
(1 time)
AUC (1 time)
CFU-GM (1 time)
I-DOX (1 time)
1990 Pharmacology and clinical toxicity of 4'-iodo-4'-deoxydoxorubicin: an example of successful application of pharmacokinetics to dose escalation in phase I trials.
52  I:Poly C causing a 50% inhibition
(1 time)
Pharmacology
(1 time)
--- 1998 Interferon-inducer polyriboinosinic-polyribocytidylic acid: a potent anti-gastric ulcer agent and inhibitor of the gastric proton pump in rats.
53  IC50 < 1 mumol x L(-1), such as toremifene citrate
(1 time)
Pharmacology
(1 time)
--- 2015 [Study of gonadal hormone drugs in blocking filovirus entry of cells in vitro].
54  IC50 of 0.04 M comparable to SB203580
(1 time)
Biochemistry
(1 time)
--- 2019 Design and molecular modeling of novel P38alpha MAPK inhibitors targeting breast cancer, synthesized from oxygen heterocyclic natural compounds.
55  IC50 value of 1.2muM, similar to that of CA-4
(1 time)
Chemistry
(1 time)
CA-4 (1 time)
2018 2-Alkoxycarbonyl-3-arylamino-5-substituted thiophenes as a novel class of antimicrotubule agents: Design, synthesis, cell growth and tubulin polymerization inhibition.
56  IC50 values for normal cells MCF10A
(1 time)
Medicine, Chinese Traditional
(1 time)
ADHC-AXpn (1 time)
DHC-Xpn (1 time)
2016 Novel cycloartane triterpenoid from Cimicifuga foetida (Sheng ma) induces mitochondrial apoptosis via inhibiting Raf/MEK/ERK pathway and Akt phosphorylation in human breast carcinoma MCF-7 cells.
57  IC50 values identical to that of 1
(1 time)
Chemistry
(1 time)
--- 2004 Synthesis, antiprotozoal and cytotoxic activities of new N-(3,4-dimethyl-5-isoxazolyl)-1,2-naphthoquinone-4-amino derivatives.
58  IC50 values in a range comparable to those of 1
(1 time)
Chemistry
(1 time)
--- 2004 Synthesis, antiprotozoal and cytotoxic activities of new N-(3,4-dimethyl-5-isoxazolyl)-1,2-naphthoquinone-4-amino derivatives.
59  IC50 values of 1-4
(1 time)
Chemistry
(1 time)
--- 2014 New ruthenium(II) arene complexes of anthracenyl-appended diazacycloalkanes: effect of ligand intercalation and hydrophobicity on DNA and protein binding and cleavage and cytotoxicity.
60  IC50 values on both TbrPDEB1
(1 time)
Biochemistry
(1 time)
HAT (1 time)
2016 Synthesis and evaluation of analogs of the phenylpyridazinone NPD-001 as potent trypanosomal TbrPDEB1 phosphodiesterase inhibitors and in vitro trypanocidals.
61  IC50 were determined for thetinctures A and B
(1 time)
MIC (1 time)
2017 Chemical and microbiological characterization of tinctures and microcapsules loaded with Brazilian red propolis extract.
62  IC50, and in DU4475 cells treated with drug A
(1 time)
Diagnostic Imaging
(1 time)
CLPS (1 time)
2001 1H NMR visible lipids are induced by phosphonium salts and 5-fluorouracil in human breast cancer cells.
63  IC50pre
(1 time)
Biochemistry
(1 time)
QSAR (1 time)
2019 Virtual design of novel Plasmodium falciparum cysteine protease falcipain-2 hybrid lactone-chalcone and isatin-chalcone inhibitors probing the S2 active site pocket.
64  IC50s < 20 mug/ml, seven were against T. b. rhodesiense
(1 time)
Pharmacology
(1 time)
SI (1 time)
SIs (1 time)
2019 In vitro antiplasmodial, antitrypanosomal and antileishmanial activities of selected medicinal plants from Ugandan flora: Refocusing into multi-component potentials.
65  IC50s comparable to that of artemisinin
(1 time)
Chemistry
(1 time)
--- 2015 Structure-activity relationship of hybrids of Cinchona alkaloids and bile acids with invitro antiplasmodial and antitrypanosomal activities.
66  IC50 = 1.94 mug/ml, which is comparable to that of nalidixic acid
(1 time)
Biochemistry
(1 time)
--- 2018 Synthesis, antimicrobial activity and molecular modeling study of 3-(5-amino-(2H)-1,2,4-triazol-3-yl]-naphthyridinones as potential DNA-gyrase inhibitors.
67  icELISA possesses a concentration of producing 50% inhibition
(1 time)
Chemistry
(1 time)
CAP (1 time)
icELISA (1 time)
2014 Development of a sensitive monoclonal antibody-based indirect competitive enzyme-linked immunosorbent assay for analysing chlorantraniliprole residues.
68  idarubicin concentration resulting in 50% inhibition
(1 time)
Neoplasms
(1 time)
--- 1988 Phase I clinical trial of orally administered 4-demethoxydaunorubicin (idarubicin) with pharmacokinetic and in vitro drug sensitivity testing in children with refractory leukemia.
69  II at the apparent concentrations producing 50% inhibition
(1 time)
Physiology
(1 time)
U-II (1 time)
1987 Contraction of major artery segments of rat by fish neuropeptide urotensin II.
70  II that caused 50% inhibition
(1 time)
Chemistry
(1 time)
cdELISA (1 time)
ciELISA (1 time)
KLH (1 time)
2006 A sensitive enzyme-linked immunosorbent assay for detecting carcinogenic aristolochic acid in herbal remedies.
71  IK with concentration needed to obtain 50% of the block
(1 time)
Drug Therapy
(1 time)
hERG (1 time)
1998 Blockade of HERG and Kv1.5 by ketoconazole.
72  imatinib-mediated apoptosis with a concentration inhibiting growth by 50
(1 time)
Neoplasms
(1 time)
CI (1 time)
SCF (1 time)
2002 Potential use of imatinib in Ewing's Sarcoma: evidence for in vitro and in vivo activity.
73  IMI binding to the Drosophila or Musca nAChR by 50
(1 time)
Biochemistry
(1 time)
IMI (1 time)
nAChR (1 time)
1997 Synthesis of a novel [125I]neonicotinoid photoaffinity probe for the Drosophila nicotinic acetylcholine receptor.
74  imidaclothiz producing 50% inhibition of the signal
(1 time)
Chemistry Techniques, Analytical
(1 time)
HPLC (1 time)
MNPs (1 time)
RSDs (1 time)
2017 Upconversion fluorescence immunoassay for imidaclothiz by magnetic nanoparticle separation.
75  improved assay performance, giving 50% B/B0
(1 time)
Chemistry Techniques, Analytical
(1 time)
--- 2010 Dipstick format of an improved ELISA for on-site atrazine monitoring in water in Pakistan.
76  in vitro 50% of enzymatic activity
(1 time)
Endocrinology
(1 time)
AZ (1 time)
CA (1 time)
1999 Inhibitory effects of cadmium on carbonic anhydrase activity and ionic regulation of the estuarine crab Chasmagnathus granulata (Decapoda, Grapsidae).
77  in vitro growth of 4 cultured NSCLC lines by 50
(1 time)
Neoplasms
(1 time)
AUC (1 time)
CDDP (1 time)
NSCLC (1 time)
1995 Pharmacokinetic correlation between experimental and clinical effects on human non-small cell lung cancers of cis-diammineglycolatoplatinum (254-S) and cis-diamminedichloroplatinum.
78  in vitro; the concentrations at which 50% of parasites were killed
(1 time)
Biochemistry
(1 time)
ER (1 time)
HAT (1 time)
VSG (1 time)
2009 Post-translational import of protein into the endoplasmic reticulum of a trypanosome: an in vitro system for discovery of anti-trypanosomal chemical entities.
79  inactivate 50% of 7 microM GAPDH
(1 time)
Biochemistry
(1 time)
GAPDH (1 time)
GAPDH-SH (1 time)
1998 Glyceraldehyde-3-phosphate dehydrogenase inactivation by peroxynitrite.
80  incorporation of 3H-leucine by 50% at a concentration
(1 time)
Neoplasms
(1 time)
SCLC (1 time)
1991 Cytotoxic activity of ricin A chain immunotoxins recognising cluster 1, w4 and 5A antigens associated with human small cell lung cancer.
81  increased by ODS and subsequent AG50W purifications
(1 time)
Biochemistry
(1 time)
ACE (1 time)
1999 Preparation and characterization of novel bioactive peptides responsible for angiotensin I-converting enzyme inhibition from wheat germ.
82  increased the 50% twitch depression
(1 time)
Genetics
(1 time)
DEX (1 time)
nAChR (1 time)
NDMRs (1 time)
2014 Different magnitude of resistance to non-depolarizing muscle relaxants in dexamethasone-treated rat diaphragm associated with altered acetylcholine receptor expression.
83  increased the dose producing 50% inhibition of enzyme activity
(1 time)
Biochemistry
(1 time)
--- 1989 Comparative ability of digoxin and an aminosugar cardiac glycoside to bind to and inhibit Na+,K+-adenosine triphosphatase. Effect of potassium.
84  increases in LDH release by 50
(1 time)
Pharmacology
(1 time)
LDH (1 time)
TTX (1 time)
1995 Neuroprotective profile of lifarizine (RS-87476) in rat cerebrocortical neurones in culture.
85  increasing the concentration needed to inhibit binding by 50
(1 time)
Hematology
(1 time)
GC (1 time)
GPIb (1 time)
vWF (1 time)
1986 Partial characterization of a binding site for von Willebrand factor on glycocalicin.
86  increasing time of exposure, culminating in a 50% growth inhibition
(1 time)
Neoplasms
(1 time)
--- 1997 Genistein inhibits growth of B16 melanoma cells in vivo and in vitro and promotes differentiation in vitro.
87  incubation of 48-72 h, by 50
(1 time)
Parasitology
(1 time)
--- 2006 Fractions of an antimalarial neem-leaf extract have activities superior to chloroquine, and are gametocytocidal.
88  incubation, the concentrations of 50 percent inhibition
(1 time)
Environmental Health
(1 time)
EGME (1 time)
MAA (1 time)
MALD (1 time)
2002 Involvement of caspase 3 mediated apoptosis in hematopoietic cytotoxicity of metabolites of ethylene glycol monomethyl ether.
89  indica, respectively, exhibited anti-RSV activity with 50% inhibition
(1 time)
Complementary Therapies
(1 time)
CPE (1 time)
HSV-1 (1 time)
RSV (1 time)
2004 Antiviral activities of medicinal herbs traditionally used in southern mainland China.
90  indicated the 50% inhibition of the control
(1 time)
Chemistry
(1 time)
ELISA (1 time)
icELISA (1 time)
2017 Construction of an Immunized Rabbit Phage Display Library for Selecting High Activity against Bacillus thuringiensis Cry1F Toxin Single-Chain Antibodies.
91  Indirect competitive ELISA showed 50% displacement
(1 time)
Chemistry Techniques, Analytical
(1 time)
LC (1 time)
m-CPBA (1 time)
2001 Enzyme immunoassay for aflatoxin B1-lysine adduct and its validation.
92  indirect-acting alpha-adrenenoceptor agonists by 50
(1 time)
Neurology
(1 time)
--- 2007 The classical competitive antagonism of phentolamine on smooth muscle preparations, investigated by two procedures.
93  individual values of tacrolimus 50% inhibition of lymphocyte proliferation
(1 time)
CMV (1 time)
LIST (1 time)
2012 Clinical Significance of the Pharmacological Efficacy of Tacrolimus Estimated by the Lymphocyte Immunosuppressant Sensitivity Test (LIST) Before and After Renal Transplantation.
94  induce 50% cell death
(1 time)
Hematology
(1 time)
CLL (1 time)
PARP (1 time)
PI (1 time)
2005 Adaphostin-induced apoptosis in CLL B cells is associated with induction of oxidative stress and exhibits synergy with fludarabine.
95  induce 50% inhibition of cell growth
(1 time)
Chemistry
(1 time)
GI (1 time)
2011 Synthesis and antitumoral evaluation of 7-chloro-4-quinolinylhydrazones derivatives.
96  induce 50% inhibition of DNA synthesis for CDDP-liposomes
(1 time)
Neoplasms
(1 time)
CDDP (1 time)
1989 Enhancement of both intracellular uptake and antitumor action of cisplatinum on human neuroblastoma cells by encapsulation in liposomes.
97  induce 50% inhibition of the maximal contractile response
(1 time)
Urology
(1 time)
--- 1999 An in vivo evaluation of the therapeutic potential of sympatholytic agents on premature ejaculation.
98  induce a 50% cytotoxicity
(1 time)
Hematology
(1 time)
CLL (1 time)
IFN (1 time)
1995 In vitro sensitivity of B-CLL cells to fludarabine and interferons.
99  induced 50% growth inhibition on KB cells at a concentration
(1 time)
Neoplasms
(1 time)
EGF-R (1 time)
mAb (1 time)
TAA (1 time)
1994 5-Aza-2'-deoxycytidine induces growth inhibition and upregulation of epidermal growth factor receptor on human epithelial cancer cells.
100  induced 50% inhibition of BCPCF efflux
(1 time)
Neoplasms
(1 time)
BCPCF (1 time)
2003 Flavonoids as inhibitors of MRP1-like efflux activity in human erythrocytes. A structure-activity relationship study.