1 |
IkappaB kinase
(1462 times)
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Biochemistry (270 times)
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NF-kappaB (429 times) TNF-alpha (134 times) LPS (126 times)
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1997 IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activation.
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2 |
inhibitor of kappaB kinase
(220 times)
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Biochemistry (36 times)
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NF-kappaB (102 times) TNF-alpha (28 times) TNF (18 times)
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2000 Glutathione S-transferase p elicits protection against H2O2-induced cell death via coordinated regulation of stress kinases.
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3 |
IkappaBalpha kinase
(55 times)
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Biochemistry (16 times)
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NF-kappaB (20 times) TNF (12 times) IL (5 times)
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1999 Protein kinase C and calcineurin synergize to activate IkappaB kinase and NF-kappaB in T lymphocytes.
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4 |
IkappaB kinase complex
(47 times)
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Molecular Biology (13 times)
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NF-kappaB (22 times) TNF (8 times) IL (5 times)
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1997 The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation.
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5 |
inhibitor of nuclear factor kappa-B kinase
(38 times)
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Pharmacology (11 times)
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NF-kappaB (14 times) ERK (7 times) IL-6 (7 times)
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2003 Negative regulation of FcepsilonRI-mediated mast cell activation by a ubiquitin-protein ligase Cbl-b.
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6 |
IkB kinase
(30 times)
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Allergy and Immunology (6 times)
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LPS (5 times) NF-kappaB (4 times) NF-kB (4 times)
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1999 NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase.
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7 |
inhibitor-kappaB kinase complex
(3 times)
|
Neoplasms (1 time)
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NF-kappaB (3 times) ADC (1 time) CHUK (1 time)
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2005 A selective novel low-molecular-weight inhibitor of IkappaB kinase-beta (IKK-beta) prevents pulmonary inflammation and shows broad anti-inflammatory activity.
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8 |
Ikappa beta kinase
(2 times)
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Physiology (1 time)
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HNSCC (1 time) IL-6 (1 time) NF-kappaB (1 time)
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2009 Suppression of interleukin 6 and 8 production in head and neck cancer cells with curcumin via inhibition of Ikappa beta kinase.
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9 |
IkBalpha kinase
(2 times)
|
Biochemistry (1 time)
|
ALL (1 time) ALP (1 time) IL-1beta (1 time)
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2004 Identification and characterization of the IKKalpha promoter: positive and negative regulation by ETS-1 and p53, respectively.
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10 |
phospho-IkappaB kinases
(2 times)
|
Genetics, Medical (1 time)
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NF-kappaB (2 times) DCs (1 time) DN (1 time)
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2008 Clostridium difficile toxin A promotes dendritic cell maturation and chemokine CXCL2 expression through p38, IKK, and the NF-kappaB signaling pathway.
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11 |
(NIK)-IkappaB alpha kinase
(1 time)
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Pharmacology (1 time)
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JNK (1 time) LPS (1 time) MAPKs (1 time)
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2006 Tanshinone IIA inhibits LPS-induced NF-kappaB activation in RAW 264.7 cells: possible involvement of the NIK-IKK, ERK1/2, p38 and JNK pathways.
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12 |
anti-IkappaB kinase
(1 time)
|
Biochemistry (1 time)
|
IkappaB (1 time) IL (1 time) iNOS (1 time)
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2001 A pyrrolidinone derivative inhibits cytokine-induced iNOS expression and NF-kappaB activation by preventing phosphorylation and degradation of IkappaB-alpha.
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13 |
holo-IkappaB kinase
(1 time)
|
Biochemistry (1 time)
|
---
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1999 Role of adapter function in oncoprotein-mediated activation of NF-kappaB. Human T-cell leukemia virus type I Tax interacts directly with IkappaB kinase gamma.
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14 |
IkappaB is phosphorylated by specific kinases
(1 time)
|
Cell Biology (1 time)
|
LPS (1 time) MAP (1 time)
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2003 Surfactant blocks lipopolysaccharide signaling by inhibiting both mitogen-activated protein and IkappaB kinases in human alveolar macrophages.
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15 |
IkappaB kinase-gamma
(1 time)
|
Chemistry (1 time)
|
NF-kappaB (1 time)
|
2006 Influence of hypothermia on post-ischemic inflammation: role of nuclear factor kappa B (NFkappaB).
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16 |
IkappaB kinases alpha
(1 time)
|
Allergy and Immunology (1 time)
|
ACP (1 time) Apaf-1 (1 time) Bax (1 time)
|
2018 The impaired immune function and structural integrity by dietary iron deficiency or excess in gill of fish after infection with Flavobacterium columnare: Regulation of NF-kappaB, TOR, JNK, p38MAPK, Nrf2 and MLCK signalling.
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17 |
IkappaB kinases-alpha/beta
(1 time)
|
Chemistry (1 time)
|
A375DR (1 time) BRAFi (1 time) NF-kappaB (1 time)
|
2019 Onconase Restores Cytotoxicity in Dabrafenib-Resistant A375 Human Melanoma Cells and Affects Cell Migration, Invasion and Colony Formation Capability.
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18 |
IkappaB-inducing kinase
(1 time)
|
Biotechnology (1 time)
|
Skp2 (1 time)
|
2006 IKKalpha controls p52/RelB at the skp2 gene promoter to regulate G1- to S-phase progression.
|
19 |
IkappaB-related kinases
(1 time)
|
Biochemistry (1 time)
|
IKK-2 (1 time) IKK1 (1 time) rh (1 time)
|
2002 Kinetic mechanisms of IkappaB-related kinases (IKK) inducible IKK and TBK-1 differ from IKK-1/IKK-2 heterodimer.
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20 |
IKK phosphorylation
(1 time)
|
Cell Biology (1 time)
|
ECM (1 time) ICA (1 time)
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2020 Icariin inhibits the inflammation through down-regulating NF-kappaB/HIF-2alpha signal pathways in chondrocytes.
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21 |
IKK-alpha or IKK-beta
(1 time)
|
Molecular Biology (1 time)
|
NF (1 time)
|
2010 IKK-dependent, NF-kappaB-independent control of autophagic gene expression.
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22 |
IKKalpha and IKKbeta
(1 time)
|
Allergy and Immunology (1 time)
|
mito-Q (1 time) NAC (1 time)
|
2007 High concentration of antioxidants N-acetylcysteine and mitoquinone-Q induces intercellular adhesion molecule 1 and oxidative stress by increasing intracellular glutathione.
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23 |
inflammatory markers, enzyme kB kinase
(1 time)
|
Biochemistry (1 time)
|
CGA (1 time) NAFLD (1 time) RAS (1 time)
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2019 Telmisartan and/or chlorogenic acid attenuates fructose-induced non-alcoholic fatty liver disease in rats: Implications of cross-talk between angiotensin, the sphingosine kinase/sphingoine-1-phosphate pathway, and TLR4 receptors.
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24 |
information, knowledge, and knowhow
(1 time)
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Health Systems Agencies (1 time)
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CLHS (1 time) IBD (1 time)
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2021 Getting what is needed, when it's needed: Sharing information, knowledge, and know-how in a Collaborative Learning Health System.
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25 |
inhibited the steps TAK1-->IkappaB kinase
(1 time)
|
Neoplasms (1 time)
|
AML (1 time) ROS (1 time)
|
2010 Antineoplastic mechanisms of niclosamide in acute myelogenous leukemia stem cells: inactivation of the NF-kappaB pathway and generation of reactive oxygen species.
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26 |
inhibitor kappa B kinase signalosome
(1 time)
|
Physiological Phenomena (1 time)
|
CHC (1 time) IkappaB (1 time)
|
2014 Clathrin complexes with the inhibitor kappa B kinase signalosome: imaging the interactome.
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27 |
inhibitor of kappa B factor kinase
(1 time)
|
Allergy and Immunology (1 time)
|
PKCtheta (1 time)
|
2000 The physical association of protein kinase C theta with a lipid raft-associated inhibitor of kappa B factor kinase (IKK) complex plays a role in the activation of the NF-kappa B cascade by TCR and CD28.
|
28 |
inhibitor of kappaB protein kinase
(1 time)
|
Biomedical Engineering (1 time)
|
Cbl (1 time) ECs (1 time) FAK (1 time)
|
2009 Shear Stress Regulates the Flk-1/Cbl/PI3K/NF-kappaB Pathway Via Actin and Tyrosine Kinases.
|
29 |
Inverse Kinematics Knee
(1 time)
|
Diagnostic Imaging (1 time)
|
AP (1 time) FKK (1 time) ML (1 time)
|
2007 An inverse kinematics model for post-operative knee. Ligament parameters estimation from knee motion.
|
30 |
Ismall ka, CyrillicB kinase
(1 time)
|
Cell Biology (1 time)
|
HSP27 (2 times) TRAF6 (1 time)
|
2008 HSP27 regulates IL-1 stimulated IKK activation through interacting with TRAF6 and affecting its ubiquitination.
|
31 |
NFkappaB-IkappaB kinase
(1 time)
|
Endocrinology (1 time)
|
ER (1 time) KO (1 time)
|
2020 Effect of KCNH6 on Hepatic Endoplasmic Reticulum Stress and Glucose Metabolism.
|
32 |
phospho-IkB kinase concentration
(1 time)
|
Medicine (1 time)
|
COX-2 (1 time) PR (1 time)
|
2010 A computer simulation of progesterone and Cox2 inhibitor treatment for preterm labor.
|
33 |
phosphorylated-IkappaB kinase
(1 time)
|
Medicine (1 time)
|
ACN (1 time) GSH-Px (1 time) MDA (1 time)
|
2017 Effects of acrylonitrile-induced oxidative stress on testicular apoptosis through activation of NF-kappaB signaling pathway in male sprague dawley rats.
|
34 |
Ras-Raf-IkappaB kinase
(1 time)
|
Virology (1 time)
|
LTR (1 time) PKR (1 time) TLR (1 time)
|
2005 Leukemia virus long terminal repeat activates NFkappaB pathway by a TLR3-dependent mechanism.
|