| 1 |
IkappaB kinase
(1462 times)
|
Biochemistry
(270 times)
|
NF-kappaB (429 times)
TNF-alpha (134 times)
LPS (126 times)
|
1997 IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activation.
|
| 2 |
inhibitor of kappaB kinase
(220 times)
|
Biochemistry
(36 times)
|
NF-kappaB (102 times)
TNF-alpha (28 times)
TNF (18 times)
|
2000 Glutathione S-transferase p elicits protection against H2O2-induced cell death via coordinated regulation of stress kinases.
|
| 3 |
IkappaBalpha kinase
(55 times)
|
Biochemistry
(16 times)
|
NF-kappaB (20 times)
TNF (12 times)
IL (5 times)
|
1999 Protein kinase C and calcineurin synergize to activate IkappaB kinase and NF-kappaB in T lymphocytes.
|
| 4 |
IkappaB kinase complex
(47 times)
|
Molecular Biology
(13 times)
|
NF-kappaB (22 times)
TNF (8 times)
IL (5 times)
|
1997 The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation.
|
| 5 |
inhibitor of nuclear factor kappa-B kinase
(38 times)
|
Pharmacology
(11 times)
|
NF-kappaB (14 times)
ERK (7 times)
IL-6 (7 times)
|
2003 Negative regulation of FcepsilonRI-mediated mast cell activation by a ubiquitin-protein ligase Cbl-b.
|
| 6 |
IkB kinase
(30 times)
|
Allergy and Immunology
(6 times)
|
LPS (5 times)
NF-kappaB (4 times)
NF-kB (4 times)
|
1999 NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase.
|
| 7 |
inhibitor-kappaB kinase complex
(3 times)
|
Neoplasms
(1 time)
|
NF-kappaB (3 times)
ADC (1 time)
CHUK (1 time)
|
2005 A selective novel low-molecular-weight inhibitor of IkappaB kinase-beta (IKK-beta) prevents pulmonary inflammation and shows broad anti-inflammatory activity.
|
| 8 |
Ikappa beta kinase
(2 times)
|
Physiology
(1 time)
|
HNSCC (1 time)
IL-6 (1 time)
NF-kappaB (1 time)
|
2009 Suppression of interleukin 6 and 8 production in head and neck cancer cells with curcumin via inhibition of Ikappa beta kinase.
|
| 9 |
IkBalpha kinase
(2 times)
|
Biochemistry
(1 time)
|
ALL (1 time)
ALP (1 time)
IL-1beta (1 time)
|
2004 Identification and characterization of the IKKalpha promoter: positive and negative regulation by ETS-1 and p53, respectively.
|
| 10 |
phospho-IkappaB kinases
(2 times)
|
Genetics, Medical
(1 time)
|
NF-kappaB (2 times)
DCs (1 time)
DN (1 time)
|
2008 Clostridium difficile toxin A promotes dendritic cell maturation and chemokine CXCL2 expression through p38, IKK, and the NF-kappaB signaling pathway.
|
| 11 |
(NIK)-IkappaB alpha kinase
(1 time)
|
Pharmacology
(1 time)
|
JNK (1 time)
LPS (1 time)
MAPKs (1 time)
|
2006 Tanshinone IIA inhibits LPS-induced NF-kappaB activation in RAW 264.7 cells: possible involvement of the NIK-IKK, ERK1/2, p38 and JNK pathways.
|
| 12 |
anti-IkappaB kinase
(1 time)
|
Biochemistry
(1 time)
|
IkappaB (1 time)
IL (1 time)
iNOS (1 time)
|
2001 A pyrrolidinone derivative inhibits cytokine-induced iNOS expression and NF-kappaB activation by preventing phosphorylation and degradation of IkappaB-alpha.
|
| 13 |
holo-IkappaB kinase
(1 time)
|
Biochemistry
(1 time)
|
---
|
1999 Role of adapter function in oncoprotein-mediated activation of NF-kappaB. Human T-cell leukemia virus type I Tax interacts directly with IkappaB kinase gamma.
|
| 14 |
IkappaB is phosphorylated by specific kinases
(1 time)
|
Cell Biology
(1 time)
|
LPS (1 time)
MAP (1 time)
|
2003 Surfactant blocks lipopolysaccharide signaling by inhibiting both mitogen-activated protein and IkappaB kinases in human alveolar macrophages.
|
| 15 |
IkappaB kinase-gamma
(1 time)
|
Chemistry
(1 time)
|
NF-kappaB (1 time)
|
2006 Influence of hypothermia on post-ischemic inflammation: role of nuclear factor kappa B (NFkappaB).
|
| 16 |
IkappaB kinases alpha
(1 time)
|
Allergy and Immunology
(1 time)
|
ACP (1 time)
Apaf-1 (1 time)
Bax (1 time)
|
2018 The impaired immune function and structural integrity by dietary iron deficiency or excess in gill of fish after infection with Flavobacterium columnare: Regulation of NF-kappaB, TOR, JNK, p38MAPK, Nrf2 and MLCK signalling.
|
| 17 |
IkappaB kinases-alpha/beta
(1 time)
|
Chemistry
(1 time)
|
A375DR (1 time)
BRAFi (1 time)
NF-kappaB (1 time)
|
2019 Onconase Restores Cytotoxicity in Dabrafenib-Resistant A375 Human Melanoma Cells and Affects Cell Migration, Invasion and Colony Formation Capability.
|
| 18 |
IkappaB-inducing kinase
(1 time)
|
Biotechnology
(1 time)
|
Skp2 (1 time)
|
2006 IKKalpha controls p52/RelB at the skp2 gene promoter to regulate G1- to S-phase progression.
|
| 19 |
IkappaB-related kinases
(1 time)
|
Biochemistry
(1 time)
|
IKK-2 (1 time)
IKK1 (1 time)
rh (1 time)
|
2002 Kinetic mechanisms of IkappaB-related kinases (IKK) inducible IKK and TBK-1 differ from IKK-1/IKK-2 heterodimer.
|
| 20 |
IKK phosphorylation
(1 time)
|
Cell Biology
(1 time)
|
ECM (1 time)
ICA (1 time)
|
2020 Icariin inhibits the inflammation through down-regulating NF-kappaB/HIF-2alpha signal pathways in chondrocytes.
|
| 21 |
IKK-alpha or IKK-beta
(1 time)
|
Molecular Biology
(1 time)
|
NF (1 time)
|
2010 IKK-dependent, NF-kappaB-independent control of autophagic gene expression.
|
| 22 |
IKKalpha and IKKbeta
(1 time)
|
Allergy and Immunology
(1 time)
|
mito-Q (1 time)
NAC (1 time)
|
2007 High concentration of antioxidants N-acetylcysteine and mitoquinone-Q induces intercellular adhesion molecule 1 and oxidative stress by increasing intracellular glutathione.
|
| 23 |
inflammatory markers, enzyme kB kinase
(1 time)
|
Biochemistry
(1 time)
|
CGA (1 time)
NAFLD (1 time)
RAS (1 time)
|
2019 Telmisartan and/or chlorogenic acid attenuates fructose-induced non-alcoholic fatty liver disease in rats: Implications of cross-talk between angiotensin, the sphingosine kinase/sphingoine-1-phosphate pathway, and TLR4 receptors.
|
| 24 |
information, knowledge, and knowhow
(1 time)
|
Health Systems Agencies
(1 time)
|
CLHS (1 time)
IBD (1 time)
|
2021 Getting what is needed, when it's needed: Sharing information, knowledge, and know-how in a Collaborative Learning Health System.
|
| 25 |
inhibited the steps TAK1-->IkappaB kinase
(1 time)
|
Neoplasms
(1 time)
|
AML (1 time)
ROS (1 time)
|
2010 Antineoplastic mechanisms of niclosamide in acute myelogenous leukemia stem cells: inactivation of the NF-kappaB pathway and generation of reactive oxygen species.
|
| 26 |
inhibitor kappa B kinase signalosome
(1 time)
|
Physiological Phenomena
(1 time)
|
CHC (1 time)
IkappaB (1 time)
|
2014 Clathrin complexes with the inhibitor kappa B kinase signalosome: imaging the interactome.
|
| 27 |
inhibitor of kappa B factor kinase
(1 time)
|
Allergy and Immunology
(1 time)
|
PKCtheta (1 time)
|
2000 The physical association of protein kinase C theta with a lipid raft-associated inhibitor of kappa B factor kinase (IKK) complex plays a role in the activation of the NF-kappa B cascade by TCR and CD28.
|
| 28 |
inhibitor of kappaB protein kinase
(1 time)
|
Biomedical Engineering
(1 time)
|
Cbl (1 time)
ECs (1 time)
FAK (1 time)
|
2009 Shear Stress Regulates the Flk-1/Cbl/PI3K/NF-kappaB Pathway Via Actin and Tyrosine Kinases.
|
| 29 |
Inverse Kinematics Knee
(1 time)
|
Diagnostic Imaging
(1 time)
|
AP (1 time)
FKK (1 time)
ML (1 time)
|
2007 An inverse kinematics model for post-operative knee. Ligament parameters estimation from knee motion.
|
| 30 |
Ismall ka, CyrillicB kinase
(1 time)
|
Cell Biology
(1 time)
|
HSP27 (2 times)
TRAF6 (1 time)
|
2008 HSP27 regulates IL-1 stimulated IKK activation through interacting with TRAF6 and affecting its ubiquitination.
|
| 31 |
NFkappaB-IkappaB kinase
(1 time)
|
Endocrinology
(1 time)
|
ER (1 time)
KO (1 time)
|
2020 Effect of KCNH6 on Hepatic Endoplasmic Reticulum Stress and Glucose Metabolism.
|
| 32 |
phospho-IkB kinase concentration
(1 time)
|
Medicine
(1 time)
|
COX-2 (1 time)
PR (1 time)
|
2010 A computer simulation of progesterone and Cox2 inhibitor treatment for preterm labor.
|
| 33 |
phosphorylated-IkappaB kinase
(1 time)
|
Medicine
(1 time)
|
ACN (1 time)
GSH-Px (1 time)
MDA (1 time)
|
2017 Effects of acrylonitrile-induced oxidative stress on testicular apoptosis through activation of NF-kappaB signaling pathway in male sprague dawley rats.
|
| 34 |
Ras-Raf-IkappaB kinase
(1 time)
|
Virology
(1 time)
|
LTR (1 time)
PKR (1 time)
TLR (1 time)
|
2005 Leukemia virus long terminal repeat activates NFkappaB pathway by a TLR3-dependent mechanism.
|
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