| 1 |
interleukin-2
(13718 times)
|
Allergy and Immunology
(4889 times)
|
IFN-gamma (1533 times)
NK (1122 times)
TNF-alpha (868 times)
|
1980 Biochemical and biological characterization of lymphocyte regulatory molecules. V. Identification of an interleukin 2-producing human leukemia T cell line.
|
| 2 |
cytokines--interleukin 2
(4 times)
|
Environmental Health
(1 time)
|
IFN-gamma (3 times)
TNF-alpha (2 times)
Con A (1 time)
|
1994 Differential nm23 gene expression at the fetal-maternal interface.
|
| 3 |
interleukin-2 receptor
(4 times)
|
Orthopedics
(1 time)
|
ATL (1 time)
BALF (1 time)
DBP (1 time)
|
1990 Activation antigens in patients with Sjogren's syndrome.
|
| 4 |
antibody-interleukin 2
(3 times)
|
Science
(2 times)
|
EpCAM (1 time)
GM-CSF (1 time)
mGM-CSF (1 time)
|
1996 Eradication of human hepatic and pulmonary melanoma metastases in SCID mice by antibody-interleukin 2 fusion proteins.
|
| 5 |
interleukin-2 therapy
(3 times)
|
Neoplasms
(1 time)
|
ALC (1 time)
CPI (1 time)
irAEs (1 time)
|
2002 [Two cases of renal cell carcinoma with ascites after interleukin-2 therapy].
|
| 6 |
intra-lesional interleukin-2
(3 times)
|
General Surgery
(3 times)
|
RECIST (1 time)
|
2011 Intra-lesional interleukin-2 for the treatment of in-transit melanoma.
|
| 7 |
DAB(389)-interleukin-2
(2 times)
|
Neoplasms
(1 time)
|
AEs (1 time)
CR (1 time)
CTCL (1 time)
|
1993 Structure/function analysis of the transmembrane domain of DAB389-interleukin-2, an interleukin-2 receptor-targeted fusion toxin. The amphipathic helical region of the transmembrane domain is essential for the efficient delivery of the catalytic domain to the cytosol of target cells.
|
| 8 |
IL-2 complex
(2 times)
|
Microbiology
(1 time)
|
BM (1 time)
BMT (1 time)
HSV-1 (1 time)
|
2016 IL-2/alpha-IL-2 Complex Treatment Cannot Be Substituted for the Adoptive Transfer of Regulatory T cells to Promote Bone Marrow Engraftment.
|
| 9 |
interleukin-2 gene
(2 times)
|
Biochemistry
(2 times)
|
I-V (1 time)
OMP (1 time)
P. mirabilis (1 time)
|
1998 Chromatin remodeling of the interleukin-2 gene: distinct alterations in the proximal versus distal enhancer regions.
|
| 10 |
A-induced lymphoproliferation, interleukin-2
(1 time)
|
Allergy and Immunology
(1 time)
|
DEX (1 time)
gamma-IFN (1 time)
|
1993 Dexamethasone suppresses T cell-mediated immunity and enhances disease susceptibility to Eimeria mivati infection.
|
| 11 |
alpha-interleukin 2
(1 time)
|
Reproductive Medicine
(1 time)
|
IFN-gamma (1 time)
NK (1 time)
PMA (1 time)
|
2002 Cytokine production in natural killer cells and lymphocytes in pregnant women compared with women in the follicular phase of the ovarian cycle.
|
| 12 |
anti-CD20-interleukin 2
(1 time)
|
Hematology
(1 time)
|
ADCC (1 time)
FACS (1 time)
ICK (1 time)
|
2005 An anti-CD20-IL-2 immunocytokine is highly efficacious in a SCID mouse model of established human B lymphoma.
|
| 13 |
Egr1-Nab2-interleukin-2
(1 time)
|
Cell Biology
(1 time)
|
---
|
2019 Differential Interleukin-2 Transcription Kinetics Render Mouse but Not Human T Cells Vulnerable to Splicing Inhibition Early after Activation.
|
| 14 |
factors-interleukin-2
(1 time)
|
Pharmacology
(1 time)
|
2hPBG (1 time)
AST (1 time)
BMI (1 time)
|
2018 Relations of hepatic steatosis with liver functions, inflammations, glucolipid metabolism in chronic hepatitis B patients.
|
| 15 |
I-IL-2
(1 time)
|
Allergy and Immunology
(1 time)
|
BBB (1 time)
IL (1 time)
Th (1 time)
|
2004 Permeability of the mouse blood-brain barrier to murine interleukin-2: predominance of a saturable efflux system.
|
| 16 |
IGIFR expression and conversely, exposure of the 2D6
(1 time)
|
Allergy and Immunology
(1 time)
|
IGIF (1 time)
IGIFR (1 time)
|
1997 A mechanism underlying synergy between IL-12 and IFN-gamma-inducing factor in enhanced production of IFN-gamma.
|
| 17 |
IL-2 enhanced MLTR
(1 time)
|
General Surgery
(1 time)
|
S.I (1 time)
|
1987 [Breast cancer-specific immunity evaluated by a new in vitro method--IL-2 enhanced MLTR].
|
| 18 |
IL-2 mAb
(1 time)
|
Science
(1 time)
|
T regs (1 time)
|
2006 Selective stimulation of T cell subsets with antibody-cytokine immune complexes.
|
| 19 |
IL-2 MS
(1 time)
|
Neurosurgery
(1 time)
|
---
|
2003 Local immunotherapy with interleukin-2 delivered from biodegradable polymer microspheres combined with interstitial chemotherapy: a novel treatment for experimental malignant glioma.
|
| 20 |
IL-2 mutein, IL-2M
(1 time)
|
Biological Science Disciplines
(1 time)
|
---
|
2020 Dynamic changes in the regulatory T-cell heterogeneity and function by murine IL-2 mutein.
|
| 21 |
IL-2 on induction of lymphokine
(1 time)
|
Neoplasms
(1 time)
|
KHF (1 time)
s.c (1 time)
|
1989 Enhancement of therapeutic effect of interleukin-2 on spontaneous pulmonary metastases of Lewis lung carcinoma by killer helper factor associated with increased induction of killer activity.
|
| 22 |
IL-2 priming
(1 time)
|
Neoplasms
(1 time)
|
MSC (1 time)
|
2015 Transcriptional profiling of interleukin-2-primed human adipose derived mesenchymal stem cells revealed dramatic changes in stem cells response imposed by replicative senescence.
|
| 23 |
IL-2 receptor
(1 time)
|
Neoplasms
(1 time)
|
Ts (1 time)
|
1991 Suppressor function of lymphocytes activated in in vitro co-culture against autologous tumor cells and expanded in interleukin-2.
|
| 24 |
IL-2 Site7
(1 time)
|
Allergy and Immunology
(1 time)
|
---
|
2013 Methylation of IL-2 promoter at birth alters the risk of asthma exacerbations during childhood.
|
| 25 |
IL-2 solution
(1 time)
|
Allergy and Immunology
(1 time)
|
DC (1 time)
IL-2 micelle (1 time)
|
2014 Combination therapy with dendritic cell vaccine and IL-2 encapsulating polymeric micelles enhances intra-tumoral accumulation of antigen-specific CTLs.
|
| 26 |
IL-2, GM-CSF and TNF-alpha, and at least one of them
(1 time)
|
Allergy and Immunology
(1 time)
|
PWM (1 time)
PWM-RBC (1 time)
|
1993 Human T lymphocyte activation by pokeweed mitogen induces production of TNF-alpha and GM-CSF and helper signaling by IL-1 and IL-6 results in IL-2-dependent T cell growth.
|
| 27 |
IL-2-L
(1 time)
|
Allergy and Immunology
(1 time)
|
---
|
1988 The construction and characterization of a biologically active recombinant IL-2 containing a lysine-rich C-terminal extension.
|
| 28 |
IL-2-producing cells
(1 time)
|
Allergy and Immunology
(1 time)
|
CTL-P (1 time)
MLC (1 time)
SC (1 time)
|
1988 Dynamics of cytotoxic T lymphocyte precursors in vivo assessed by change in the radiation sensitivity. Evidence for development of radiation-sensitive memory cells without clonal expansion.
|
| 29 |
IL-2: or TNF immunotherapy
(1 time)
|
Health Services
(1 time)
|
NO (1 time)
TNF (1 time)
|
1996 Prevention of cytokine-induced hypotension in cancer patients by the pineal hormone melatonin.
|
| 30 |
IL-2Lys20
(1 time)
|
Neoplasms
(1 time)
|
---
|
1991 Decreased tumorigenicity of a transplantable rat sarcoma following transfer and expression of an IL-2 cDNA.
|
| 31 |
IL-2MAB602
(1 time)
|
Neoplasms
(1 time)
|
IL-12 (1 time)
|
2015 Cancer-targeted IL-12 controls human rhabdomyosarcoma by senescence induction and myogenic differentiation.
|
| 32 |
IL-2R alpha, IL-2R beta-chain
(1 time)
|
Transplantation
(1 time)
|
---
|
2000 Quantitative flow cytometry to measure the TNF-alpha and IL-2 system after heart transplantation.
|
| 33 |
IL-2R gamma
(1 time)
|
Allergy and Immunology
(1 time)
|
SCID (1 time)
|
1996 Interleukin-2 receptor common gamma-chain signaling cytokines regulate activated T cell apoptosis in response to growth factor withdrawal: selective induction of anti-apoptotic (bcl-2, bcl-xL) but not pro-apoptotic (bax, bcl-xS) gene expression.
|
| 34 |
Il-2rgamma
(1 time)
|
Medicine
(1 time)
|
FAH (1 time)
HBV (1 time)
HCV (1 time)
|
2010 Human liver chimeric mice provide a model for hepatitis B and C virus infection and treatment.
|
| 35 |
in vitro long-term interleukin-2
(1 time)
|
Allergy and Immunology
(1 time)
|
mAb (1 time)
NK (1 time)
VCAM-1 (1 time)
|
1996 Expression and function of alpha 4/beta 7 integrin on human natural killer cells.
|
| 36 |
including lectins, interleukin-2
(1 time)
|
Allergy and Immunology
(1 time)
|
mAbs (1 time)
PHA (1 time)
|
1989 Potentiation of interleukin-2 production and its binding by monoclonal antibodies to the gangliosides GD3 and GD2.
|
| 37 |
including tumor necrosis factor (TNF-alpha),interleukin-2
(1 time)
|
Physiology
(1 time)
|
COS (1 time)
FGSCs (1 time)
MVH (1 time)
|
2017 [Effects of COS on promoting the pathological ovarian aging mice ovarian function by regulating immune function].
|
| 38 |
inflammatory factor-2
(1 time)
|
Neoplasms
(1 time)
|
CD31 (1 time)
EOC (1 time)
ITGbeta1 (1 time)
|
2018 Inhibition effect of triptolide on human epithelial ovarian cancer via adjusting cellular immunity and angiogenesis.
|
| 39 |
interleukin-2 and -6
(1 time)
|
Psychopharmacology
(1 time)
|
HC (1 time)
PANSS (1 time)
SCH (1 time)
|
2009 Superoxide dismutase and cytokines in chronic patients with schizophrenia: association with psychopathology and response to antipsychotics.
|
| 40 |
interleukin-2 antagonists
(1 time)
|
Transplantation
(1 time)
|
AZA (1 time)
MMF (1 time)
|
2008 Influence of immunosuppressive regimens on short-term morbidity and mortality in heart transplantation.
|
| 41 |
interleukin-2 heterozygous
(1 time)
|
Allergy and Immunology
(1 time)
|
DSS (1 time)
|
2005 Reduced susceptibility to dextran sulphate sodium-induced colitis in the interleukin-2 heterozygous (IL-2) mouse.
|
| 42 |
interleukin-2 proteins
(1 time)
|
Allergy and Immunology
(1 time)
|
NK (1 time)
PBMC (1 time)
|
1985 Comparison of the biological activities of human recombinant interleukin-2(125) and native interleukin-2.
|
| 43 |
interleukin-2-activated
(1 time)
|
Allergy and Immunology
(1 time)
|
PRV (1 time)
SLA (1 time)
|
1997 Establishment and characterization of porcine cytolytic cell lines and clones.
|
| 44 |
Interleukin-2/T-cell growth factor
(1 time)
|
Pharmacology
(1 time)
|
CTL (1 time)
|
1985 Modulation of in vitro cellular immune response by histamine agonists or antagonists in murine species.
|
| 45 |
interleukins 2, 6 and 8
(1 time)
|
Pulmonary Medicine
(1 time)
|
IFN-gamma (1 time)
IL-12 (1 time)
TNF-alpha (1 time)
|
1995 Functions of T-cell subsets and cytokines in mycobacterial infections.
|
| 46 |
intraperitoneally every 12 hours for 28 days; group IB
(1 time)
|
General Surgery
(1 time)
|
LAK (1 time)
|
1990 Adoptive immunotherapy of human pancreatic cancer with lymphokine-activated killer cells and interleukin-2 in a nude mouse model.
|
| 47 |
intraperitoneally with PBMC+Interleukin-2
(1 time)
|
Neoplasms
(1 time)
|
NK (1 time)
|
2016 Anti-ovarian tumor response of donor peripheral blood mononuclear cells is due to infiltrating cytotoxic NK cells.
|
| 48 |
ISIL in 20% PDLG
(1 time)
|
Biochemistry
(1 time)
|
ISFI (1 time)
ISILs (1 time)
NMP (1 time)
|
2012 A novel injectable in situ forming poly-DL-lactide and DL-lactide/glycolide implant containing lipospheres for controlled drug delivery.
|
| 49 |
PHA-induced lymphokine--interleukin 2
(1 time)
|
Allergy and Immunology
(1 time)
|
IFN-gamma (1 time)
mAbs (1 time)
PMNC (1 time)
|
1988 Fenoterol effects on the in vitro immune response.
|
| 50 |
PspA-interleukin-2
(1 time)
|
Allergy and Immunology
(1 time)
|
GM-CSF (1 time)
IgG1 (1 time)
PspA (1 time)
|
1998 Enhanced protective antibody responses to PspA after intranasal or subcutaneous injections of PspA genetically fused to granulocyte-macrophage colony-stimulating factor or interleukin-2.
|
| 51 |
ribavirin-interleukin-2
(1 time)
|
Gastroenterology
(1 time)
|
HCV (1 time)
IFN-alpha (1 time)
|
2006 Pilot study of interferon-alpha-ribavirin-interleukin-2 for treatment of nonresponder patients with severe liver disease infected by hepatitis C virus genotype 1.
|
| 52 |
scFv-Fc-interleukin 2
(1 time)
|
Pharmacology
(1 time)
|
ADCC (1 time)
|
2007 Efficient growth inhibition of ErbB2-overexpressing tumor cells by anti-ErbB2 ScFv-Fc-IL-2 fusion protein in vitro and in vivo.
|
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