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Abbreviation: IkappaB
Appearance Frequency: 783 time(s)
Long forms: 60

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Long Form No. Long Form Research Area Co-occurring Abbreviation PubMed/MEDLINE Info. (Year, Title)
inhibitor of kappaB
(597 times)
Pharmacology
(105 times)
NF-kappaB (362 times)
LPS (138 times)
TNF-alpha (98 times)
1996 Inhibition of NF-kappaB/Rel induces apoptosis of murine B cells.
inhibitor of nuclear factor-kappaB
(57 times)
Pharmacology
(8 times)
NF-kappaB (30 times)
ERK (7 times)
JNK (7 times)
1998 IkappaB is a substrate for a selective pathway of lysosomal proteolysis.
inhibitory factor-kappaB
(30 times)
Pharmacology
(5 times)
NF-kappaB (22 times)
NO (10 times)
iNOS (8 times)
1998 Heat shock inhibits cytokine-induced nitric oxide synthase expression by rat and human islets.
NF-kappaB inhibitor
(14 times)
Endocrinology
(3 times)
NF-kappaB (7 times)
TNF-alpha (3 times)
IL (2 times)
2001 Induction of beta-transducin repeat-containing protein by JNK signaling and its role in the activation of NF-kappaB.
I kappa B
(12 times)
Cell Biology
(3 times)
NF-kappaB (10 times)
IKK (2 times)
iNOS (2 times)
2004 Expanded nuclear roles for IkappaBs.
inhibitor of kappaB protein
(8 times)
Allergy and Immunology
(2 times)
NF-kappaB (4 times)
LPS (3 times)
iNOS (2 times)
1999 Inactivation of the inhibitory kappaB protein kinase/nuclear factor kappaB pathway by Par-4 expression potentiates tumor necrosis factor alpha-induced apoptosis.
NF-kappaB inhibitor protein
(4 times)
Zoology
(1 time)
NF-kappaB (2 times)
TNF-alpha (2 times)
CIK (1 time)
2002 Interferon gamma antagonizes interleukin-1beta-induced cyclooxygenase-2 expression and prostaglandin E(2) production in human myometrial cells.
factor-kappaB inhibitor
(3 times)
Nutritional Sciences
(1 time)
8-OHdG (1 time)
COX-2 (1 time)
GSE (1 time)
2011 Grape seed extract ameliorates tumor necrosis factor-alpha-induced inflammatory status of human umbilical vein endothelial cells.
inhibiting the phosphorylation of NF kappaB inhibitor
(3 times)
Cell Biology
(1 time)
NF-kappaB (2 times)
ER (1 time)
HDL (1 time)
2012 Pharmacologic ER stress induces non-alcoholic steatohepatitis in an animal model.
10  increased inhibitor of NF-kappaB
(2 times)
Cardiology
(1 time)
alpha 1-AT (1 time)
ICAM-1 (1 time)
IR (1 time)
2001 Alpha-1-antitrypsin and a broad spectrum metalloprotease inhibitor, RS113456, have similar acute anti-inflammatory effects.
11  inhibited by binding to NF-kappaB inhibitor
(2 times)
Science
(1 time)
CRC (2 times)
NF-kappaB (2 times)
CD (1 time)
2007 NFKB and NFKBI polymorphisms in relation to susceptibility of tumour and other diseases.
12  inhibitor of kappaB kinase
(2 times)
Allergy and Immunology
(1 time)
CLP (1 time)
GalN (1 time)
IL-18 (1 time)
2012 Protective effect of low molecular fraction of MGN-3, a modified arabinoxylan from rice bran, on acute liver injury by inhibition of NF-kappaB and JNK/MAPK expression.
13  inhibitor of transcription factor NF-kappaB
(2 times)
Environmental Health
(1 time)
COX-2 (1 time)
IL-1R (1 time)
IL-6 (1 time)
2011 The IkappaB kinase complex regulates the stability of cytokine-encoding mRNA induced by TLR-IL-1R by controlling degradation of regnase-1.
14  anti-inhibitory kappaB
(1 time)
Biochemistry
(1 time)
IL-1 alpha (1 time)
M-CSF (1 time)
NF-kappaB (1 time)
2001 Inhibitor of nuclear factor-kappaB induction by cAMP antagonizes interleukin-1-induced human macrophage-colony-stimulating-factor expression.
15  I kappa B beta protein
(1 time)
Brain
(1 time)
FFI (1 time)
HIF-1alpha (1 time)
PS (1 time)
2006 Intracerebral hemorrhage elicits aberration in cardiomyocyte contractile function and intracellular Ca2+ transients.
16  IFN-gamma, inhibitor of NF-kappaB
(1 time)
Allergy and Immunology
(1 time)
IFN (1 time)
ISGs (1 time)
ISREs (1 time)
2009 Roles of IKK-beta, IRF1, and p65 in the activation of chemokine genes by interferon-gamma.
17  IKKalpha subunits of kappaB inhibitor
(1 time)
Molecular Biology
(1 time)
IKK (1 time)
NF-kappaB (1 time)
TNF-alpha (1 time)
2003 Anandamide inhibits nuclear factor-kappaB activation through a cannabinoid receptor-independent pathway.
18  IKKbeta and inhibitor of kappa-B
(1 time)
Biochemistry
(1 time)
IKKbeta (1 time)
IL-1beta (1 time)
NALP3 (1 time)
2016 Mefunidone ameliorates renal inflammation and tubulointerstitial fibrosis via suppression of IKKbeta phosphorylation.
19  IKKbeta, nuclear factor-kappaB inhibitory proteins
(1 time)
Biology
(1 time)
AST (1 time)
IKK (1 time)
MDA (1 time)
2016 Protective effect of Sophoraflavanone G on streptozotocin (STZ)-induced inflammation in diabetic rats.
20  immunoglobulin kappa chain in B cells
(1 time)
Biochemistry
(1 time)
iNOS (1 time)
NF-kappaB (1 time)
NO (1 time)
1999 Role of tyrosine kinase activity in 2,2',2''-tripyridine-induced nitricoxide generation in macrophages.
21  inactivate inhibitor of kappaB
(1 time)
Biochemistry
(1 time)
ICAM-1 (1 time)
NF-kappaB (1 time)
PKCalpha (1 time)
2012 The NF-kappaB target genes ICAM-1 and VCAM-1 are differentially regulated during spontaneous differentiation of Caco-2 cells.
22  inactivated the NF-kappaB inhibitor
(1 time)
Neoplasms
(1 time)
BCCL (1 time)
ECM (1 time)
2019 Placenta-conditioned extracellular matrix (ECM) activates breast cancer cell survival mechanisms: A key for future distant metastases.
23  inactive NF-kappaB-inhibitor of NF-kappaB
(1 time)
Therapeutics
(1 time)
AML (1 time)
MDS (1 time)
2010 NF-kappaB as a potential therapeutic target in myelodysplastic syndromes and acute myeloid leukemia.
24  include receptors, adaptor proteins, NF-kappaB
(1 time)
Virology
(1 time)
DUBs (1 time)
HIV-1 (1 time)
NF-kappaB (1 time)
2018 Suppression of NF-kappaB Activity: A Viral Immune Evasion Mechanism.
25  included the decreased phosphorylation/degradation of NF-kappaB inhibitor
(1 time)
Allergy and Immunology
(1 time)
AD (1 time)
cAMP (1 time)
dbcAMP (1 time)
2002 Molecular mechanisms underlying cyclic AMP inhibition of macrophage dependent TNF-alpha production and neurotoxicity in response to amyloidogenic C-terminal fragment of Alzheimer's amyloid precursor protein.
26  increased hypothalamic inhibitory factor kappaB
(1 time)
Endocrinology
(1 time)
CRF (1 time)
i.c.v (1 time)
NF-kappaB (1 time)
2005 Role played by hypothalamic nuclear factor-{kappa}B in alcohol-mediated activation of the rat hypothalamic-pituitary-adrenal axis.
27  increasing the expression of nuclear factor-kappaB inhibitor
(1 time)
Drug Therapy
(1 time)
5-ASA (1 time)
NF (1 time)
PPAR (1 time)
2008 Reduction of peroxisome proliferation-activated receptor gamma expression by gamma-irradiation as a mechanism contributing to inflammatory response in rat colon: modulation by the 5-aminosalicylic acid agonist.
28  inflammation, inhibitor of nuclear factor-kappaB
(1 time)
Signal Transduction
(1 time)
--- 2008 Bacterial-modulated signaling pathways in gut homeostasis.
29  inhibited NF-kappaB activation by preventing degradation of the kappaB protein
(1 time)
Biochemistry
(1 time)
BK (1 time)
NF-kappaB (1 time)
NO (1 time)
2012 Inhibitory role of kinins on microglial nitric oxide and tumor necrosis factor-alpha production.
30  inhibitor kappa B-alpha
(1 time)
Allergy and Immunology
(1 time)
COX-2 (1 time)
IL-1beta (1 time)
iNOS (1 time)
2014 Anti-neuroinflammatory effect of aurantiamide acetate from the marine fungus Aspergillus sp. SF-5921: inhibition of NF-kappaB and MAPK pathways in lipopolysaccharide-induced mouse BV2 microglial cells.
31  inhibitor of kappa beta signaling
(1 time)
Brain
(1 time)
GLUT1 (1 time)
PDK4 (1 time)
POMC (1 time)
2009 Estradiol impairs hypothalamic molecular responses to hypoglycemia.
32  inhibitor of kappa light polypeptide gene enhancer in B-cells
(1 time)
Molecular Biology
(1 time)
AOM/DSS (1 time)
NF-kappaB1 (1 time)
TNF-alpha (1 time)
2016 The B-cell tumor promoter Bcl-3 suppresses inflammation-associated colon tumorigenesis in epithelial cells.
33  inhibitor of kappaB factor
(1 time)
Allergy and Immunology
(1 time)
CD28RE (1 time)
JNK (1 time)
MEKK1 (1 time)
2002 Vav cooperates with CD28 to induce NF-kappaB activation via a pathway involving Rac-1 and mitogen-activated kinase kinase 1.
34  inhibitor of NF-kappaB transcription factor
(1 time)
Biochemistry
(1 time)
HOS (1 time)
2002 Induction of homologue of Slimb ubiquitin ligase receptor by mitogen signaling.
35  inhibitor of nuclear factor kappa‑light‑chain‑enhancer of activated B cells (NF‑kappaB)
(1 time)
Molecular Biology
(1 time)
MMP (1 time)
TAGLN2 (1 time)
2019 Transgelin 2 overexpression inhibits cervical cancer cell invasion and migration.
36  inhibitor of nuclear transcription factor kappaB
(1 time)
Biochemistry
(1 time)
hIKKbeta (1 time)
IKK (1 time)
KD (1 time)
2013 Crystal structure of a human IkappaB kinase beta asymmetric dimer.
37  inhibitor-kappaappa B
(1 time)
Complementary Therapies
(1 time)
alpha-SMA (1 time)
GSH-Px (1 time)
Hyp (1 time)
2017 Fuzheng Huayu Formula () prevents rat renal interstitial fibrosis induced by HgCl2 via antioxidative stress and down-regulation of nuclear factor-kappa B activity.
38  inhibitors of the NF-kappaB family
(1 time)
Allergy and Immunology
(1 time)
MZB (1 time)
NF-kappaB (1 time)
2008 IkappaBalpha is required for marginal zone B cell lineage development.
39  inhibitory domains of the Drosophila melanogaster NF-kappaB transcription factor inhibitor
(1 time)
Biology
(1 time)
CcIV (1 time)
p.p (1 time)
2007 Cloning and characterization of two Campoletis chlorideae ichnovirus vankyrin genes expressed in parasitized host Helicoverpa armigera.
40  inhibitory kappa B kinase
(1 time)
Cell Biology
(1 time)
iNOS (1 time)
miRNA (1 time)
MSCs (1 time)
2011 MicroRNA profiling reveals age-dependent differential expression of nuclear factor kappaB and mitogen-activated protein kinase in adipose and bone marrow-derived human mesenchymal stem cells.
41  inhibitory protein of nuclear factor-kappaB
(1 time)
Pharmacology
(1 time)
APS (1 time)
DN (1 time)
NF-kappaB (1 time)
2007 Merit of Astragalus polysaccharide in the improvement of early diabetic nephropathy with an effect on mRNA expressions of NF-kappaB and IkappaB in renal cortex of streptozotoxin-induced diabetic rats.
42  inhibitory proteins of the NF-kappaB inhibitor
(1 time)
Neoplasms
(1 time)
NF-kappaB (1 time)
2004 Nuclear factor-kappaB modulation as a therapeutic approach in hematologic malignancies.
43  inhibits NF-kappaB inhibitor
(1 time)
Allergy and Immunology
(1 time)
COX (1 time)
IL (1 time)
iNOS (1 time)
2013 The p38 MAPK inhibitor JLU1124 inhibits the inflammatory response induced by lipopolysaccharide through the MAPK-NF-kappaB pathway in RAW264.7 macrophages.
44  inhibits phosphorylation of nuclear factor kappaB inhibitor
(1 time)
Biochemistry
(1 time)
BCL (1 time)
IL-6 (1 time)
JNK (1 time)
2009 Adiponectin inhibits pro-inflammatory signaling in human macrophages independent of interleukin-10.
45  iNOS gene expression, NF-kappaB activation, and NF-kappaB inhibitor
(1 time)
Biochemistry
(1 time)
IKK (1 time)
IL (1 time)
iNOS (1 time)
2001 A pyrrolidinone derivative inhibits cytokine-induced iNOS expression and NF-kappaB activation by preventing phosphorylation and degradation of IkappaB-alpha.
46  iNOS production and kappa B inhibitor protein
(1 time)
Endocrinology
(1 time)
ERK (1 time)
iNOS (1 time)
JNK (1 time)
2005 Extracellular signal-regulated kinase is essential for interleukin-1-induced and nuclear factor kappaB-mediated gene expression in insulin-producing INS-1E cells.
47  interacted with inhibitor of NF-kappaB
(1 time)
Cell Biology
(1 time)
HDAC1 (1 time)
MMP9 (1 time)
NF-kappaB (1 time)
2012 PKD2 and PKD3 promote prostate cancer cell invasion by modulating NF-kappaB- and HDAC1-mediated expression and activation of uPA.
48  interaction with kappaB inhibitors
(1 time)
Hygiene
(1 time)
--- 2008 [The structure of NF- kappaB family proteins and their role in apoptosis].
49  into nucleus and NF-kappa-B inhibitor
(1 time)
Environmental Health
(1 time)
HPLC (1 time)
LTR (1 time)
MS (1 time)
2014 First report on isolation of methyl gallate with antioxidant, anti-HIV-1 and HIV-1 enzyme inhibitory activities from a mushroom (Pholiota adiposa).
50  intramitochondrial inhibitor of NF-kappaB
(1 time)
Biochemistry
(1 time)
AD (1 time)
NF-kappaB (1 time)
2014 Intromitochondrial IkappaB/NF-kappaB signaling pathway is involved in amyloid beta peptide-induced mitochondrial dysfunction.
51  NF-kappaB inhibitory subunits
(1 time)
Biochemistry
(1 time)
HIV-1 (1 time)
HOCl (1 time)
ROS (1 time)
1997 Activation of the NF-kappaB transcription factor in a T-lymphocytic cell line by hypochlorous acid.
52  NF-kappaB-inducing kinase, inhibitor of NF-kappaB
(1 time)
Metabolism
(1 time)
HO (1 time)
LPS (1 time)
MAPK (1 time)
2004 Role of NF-kappaB and p38 MAP kinase signaling pathways in the lipopolysaccharide-dependent activation of heme oxygenase-1 gene expression.
53  NF-kappaB-inhibiting factor
(1 time)
Environmental Health
(1 time)
IgM (1 time)
IKKalpha (1 time)
IKKbeta (1 time)
2013 Molecular mechanism of inflammatory response in mouse liver caused by exposure to CeCl₃.
54  NF-kappaB-inhibitory-kappaB
(1 time)
Neoplasms
(1 time)
4-HR (1 time)
NF-kappaB (1 time)
pNF-kappaB (1 time)
2011 4-hexylresorcinol inhibits NF-kappaB phosphorylation and has a synergistic effect with cisplatin in KB cells.
55  NFkappaB-inducing kinase and the phosphorylation of NFkappaB inhibitory proteins
(1 time)
Neoplasms
(1 time)
IKK (1 time)
IKK2 (1 time)
PPs (1 time)
2000 A dominant negative form of IKK2 prevents suppression of apoptosis by the peroxisome proliferator nafenopin.
56  p-IKKalpha/beta, an inhibitor of NF-kappaB
(1 time)
Environmental Health
(1 time)
COX-2 (1 time)
EMSA (1 time)
HCB (1 time)
2016 Tetrachlorobenzoquinone exhibits neurotoxicity by inducing inflammatory responses through ROS-mediated IKK/IkappaB/NF-kappaB signaling.
57  phosphorylated-inhibitor of kappa B
(1 time)
Gastroenterology
(1 time)
EMT (1 time)
IgammaB (1 time)
ILK (1 time)
2016 Integrin-linked kinase overexpression promotes epithelial-mesenchymal transition via nuclear factor-kappaB signaling in colorectal cancer cells.
58  repressors--inhibitors of kappaB
(1 time)
Biochemistry
(1 time)
AT (1 time)
COPD (1 time)
IKAP (1 time)
2013 Effects of hypoxia on adipose tissue expression of NFkappaB, IkappaBalpha, IKKgamma and IKAP in patients with chronic obstructive pulmonary disease.
59  TNF-alpha-induced kappaB inhibitor
(1 time)
Chemistry
(1 time)
AP (1 time)
CREB (1 time)
HO-1 (1 time)
2011 Andrographolide inhibits ICAM-1 expression and NF-kappaB activation in TNF-alpha-treated EA.hy926 cells.
60  total-inhibitory NFkappaB
(1 time)
Endocrinology
(1 time)
NF-kappaB (1 time)
XIAP (1 time)
2002 Involvement of inhibitory nuclear factor-kappaB (NFkappaB)-independent NFkappaB activation in the gonadotropic regulation of X-linked inhibitor of apoptosis expression during ovarian follicular development in vitro.