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Abbreviation: LC50
Appearance Frequency: 241 time(s)
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Long Form No. Long Form Research Area Co-occurring Abbreviation PubMed/MEDLINE Info. (Year, Title)
lethal concentration 50
(157 times)
Environmental Health
(47 times)
EC50 (7 times)
RF (7 times)
SOD (7 times)
1994 Toxicity of compound A in rats. Effect of a 3-hour administration.
lethal concentration for 50% mortality
(13 times)
Environmental Health
(5 times)
GC-MS (2 times)
a.i (1 time)
AChE (1 time)
1995 Acute toxicity of fluorescein to turbot (Scophthalmus maximus).
lethal concentration to 50% of the population
(10 times)
Environmental Health
(4 times)
ANOVA (1 time)
BIPV (1 time)
BZ (1 time)
2001 On the validity of classifying chemicals for persistence, bioaccumulation, toxicity, and potential for long-range transport.
lethal concentration 50% subject
(3 times)
Environmental Health
(1 time)
DT (1 time)
PBO (1 time)
2016 Status of Resistance of Bemisia tabaci (Hemiptera: Aleyrodidae) to Neonicotinoids in Iran and Detoxification by Cytochrome P450-Dependent Monooxygenases.
lethal concentration required to kill 50% of the population
(3 times)
Toxicology
(2 times)
AP-PLA2 (1 time)
BCA (1 time)
CV (1 time)
2013 Interactive effects of pesticide mixtures, predators, and environmental regimes on the toxicity of two pesticides to red-eyed tree frog larvae.
Lethal concentration to 50% of exposed organisms
(3 times)
Chemistry
(2 times)
OilToxEx (1 time)
OWD (1 time)
TAN (1 time)
2002 Development and application of an oil toxicity and exposure model, OilToxEx.
lethal concentration of 50% individuals
(2 times)
Environmental Health
(1 time)
LT50 (1 time)
PIB (1 time)
PM (1 time)
2007 Interaction of Xestia c-nigrum granulovirus with peritrophic matrix and Spodoptera litura nucleopolyhedrovirus in Spodoptera litura.
lethal concentration that kills 50% of the exposed larvae
(2 times)
Parasitology
(1 time)
LC90 (2 times)
EDX (1 time)
FTIR (1 time)
2014 Optimization and synthesis of silver nanoparticles using Isaria fumosorosea against human vector mosquitoes.
lethal concentrations for 50% of parasites
(2 times)
Medicine
(1 time)
DNK (1 time)
ROS (1 time)
2015 In vitro and in vivo anthelmintic activity of (-)-6,6'-dinitrohinokinin against schistosomula and juvenile and adult worms of Schistosoma mansoni.
10  Lethal concentrations sufficient to kill 50% of insects
(2 times)
Physiology
(1 time)
--- 1999 Selection of Beauveria bassiana and Metarhizium anisopliae isolates to control Triatoma infestans.
11  lethal exposure concentration associated with a mortality of 50
(2 times)
Environmental Health
(2 times)
AUC (1 time)
CBC (1 time)
2004 Accumulation and toxicity of cadmium in the aquatic oligochaete Tubifex tubifex: a kinetic modeling approach.
12  5-lipoxygenase, causing a 50% death rate
(1 time)
Biology
(1 time)
--- 2004 [Apoptosis in P388 leukemia cells induced by specific inhibitors of 5- and 12-lipoxygenase and the product of cyclooxygenase, prostaglandin E2].
13  B-lineage ALL samples tested, the concentration producing 50% cytotoxicity
(1 time)
Neoplasms
(1 time)
ALL (1 time)
1996 Comparative cytotoxicity of dexamethasone and prednisolone in childhood acute lymphoblastic leukemia.
14  L arsenate induced 50% mortality
(1 time)
--- 2020 Chronic arsenate exposure affects amphipod size distribution and reproduction.
15  L(-1) of silver caused 50% mortality
(1 time)
Environmental Health
(1 time)
--- 2009 Water chemistry influences the toxicity of silver to the green-lipped mussel Perna viridis.
16  LA50 was employed to predict the 96 h Cu toxicity
(1 time)
Environmental Health
(1 time)
BLM (1 time)
2012 Application of the biotic ligand model to predict copper acute toxicity to Medaka fish in typical Chinese rivers.
17  large database of concentrations causing 50% lethality
(1 time)
Biology
(1 time)
FET (1 time)
MOA (1 time)
QSARs (1 time)
2016 Development of a general baseline toxicity QSAR model for the fish embryo acute toxicity test.
18  larvae of A. ipsilon, with a 50%-lethal concentration
(1 time)
Zoology
(1 time)
--- 2018 Sublethal and Hormesis Effects of Clothianidin on the Black Cutworm (Lepidoptera: Noctuidae).
19  larvae, the concentration required to kill 50% of larvae
(1 time)
Biotechnology
(1 time)
--- 1997 Cloning and expression of the Bacillus sphaericus 2362 mosquitocidal genes in a non-toxic unicellular cyanobacterium, Synechococcus PCC6301.
20  layer causing 50% mortality
(1 time)
Environmental Health
(1 time)
AE (1 time)
EqP (1 time)
2008 Sediment toxicity of a rapidly biodegrading nonionic surfactant: Comparing the equilibrium partitioning approach with measurements in pore water.
21  LC50 values of 2.959-5.013muM compared to that of 1
(1 time)
Chemistry
(1 time)
--- 2016 Synthesis, biological activities and structure-activity relationships for new avermectin analogues.
22  leading to 50% cell death
(1 time)
Anesthesiology
(1 time)
--- 2011 Lipophilicity but not stereospecificity is a major determinant of local anaesthetic-induced cytotoxicity in human T-lymphoma cells.
23  leading to a 50% decrease in cell number
(1 time)
Gastroenterology
(1 time)
Sch B (1 time)
2004 Down-modulation of heat shock protein 70 and up-modulation of Caspase-3 during schisandrin B-induced apoptosis in human hepatoma SMMC-7721 cells.
24  lethal concentration at which 50% cells were killed
(1 time)
Molecular Biology
(1 time)
--- 2012 Effect of ascorbic acid and hydrogen peroxide on mouse neuroblastoma cells.
25  lethal concentration for 50% cell death
(1 time)
Neoplasms
(1 time)
--- 2019 Heterogeneity and Plasticity of Human Breast Cancer Cells in Response to Molecularly-Targeted Drugs.
26  lethal concentration for 50% of exposed cells
(1 time)
Toxicology
(1 time)
CAsE (1 time)
cisPt (1 time)
DMA (1 time)
2000 Studies on the mechanisms of arsenic-induced self tolerance developed in liver epithelial cells through continuous low-level arsenite exposure.
27  Lethal concentration in 50% of test species
(1 time)
Ecology
(1 time)
EC50 (1 time)
LOEC (1 time)
PNEC (1 time)
2015 Acute toxicity of peroxy sulfonated oleic acids (PSOA) to freshwater aquatic species and sludge microflora as observed in laboratory environments.
28  lethal concentration of 50% of cells
(1 time)
Dentistry
(1 time)
HP (1 time)
NR (1 time)
2015 Penetration and cytotoxicity of a bleaching gel activated by LED/laser in restored teeth.
29  lethal concentration of 50% of organisms tested
(1 time)
Chemistry
(1 time)
PFOS (1 time)
2016 Metabolomic responses to sublethal contaminant exposure in neonate and adult Daphnia magna.
30  lethal concentration of poultry litter to 50% of the earthworms
(1 time)
Environmental Health
(1 time)
FQs (1 time)
2020 Fluoroquinolone-contaminated poultry litter strongly affects earthworms as verified through lethal and sub-lethal evaluations.
31  lethal concentration on cell viability of 50
(1 time)
Natural Science Disciplines
(1 time)
--- 2017 Enhanced efficiency of cell death by lysosome-specific photodamage.
32  lethal concentration required to kill 50% of nematodes
(1 time)
Parasitology
(1 time)
AMT (1 time)
IVM (1 time)
LDT (1 time)
2022 Phytochemical modulation of P-Glycoprotein and its gene expression in an ivermectin-resistant Haemonchus contortus isolate in vitro.
33  lethal concentration required to produce a mortality of 50
(1 time)
Parasitology
(1 time)
GVCR (1 time)
2020 Molluscicidal and parasiticidal activities of Eryngium triquetrum essential oil on Schistosoma mansoni and its intermediate snail host Biomphalaria glabrata, a double impact.
34  lethal concentration that killed 50% of individuals
(1 time)
Occupational Medicine
(1 time)
CAT (1 time)
GPx (1 time)
ROS (1 time)
2012 Mortality and antioxidant responses in the planarian (Dugesia japonica) after exposure to copper.
35  lethal concentration that kills 50% of larvae
(1 time)
Parasitology
(1 time)
--- 2016 HISTOCHEMICAL EFFECTS OF SOME BIOLOGICAL AGENTS ON CULEX PIPIENS LARVAE.
36  lethal concentration to inhibit 50% of Cooperia spp. egg hatching
(1 time)
Parasitology
(1 time)
AH (1 time)
EHA (1 time)
SEM (1 time)
2015 Elucidation of Leucaena leucocephala anthelmintic-like phytochemicals and the ultrastructural damage generated to eggs of Cooperia spp.
37  lethal concentration values required to kill 50% of thenematode population
(1 time)
HF (1 time)
SCN (1 time)
VOCs (1 time)
2021 Slight induction and strong inhibition of Heterodera glycines hatching by short-chain molecules released by different plant species.
38  Lethal concentration values that kill 50% of the brine shrimps
(1 time)
Health Services Research
(1 time)
BST (1 time)
EC50 (1 time)
2012 Indigenous to Tanzania.
39  lethal concentrations at 50% of the tested populations
(1 time)
Tropical Medicine
(1 time)
kdr (1 time)
RR (1 time)
2021 Insecticide resistance in Aedes aegypti from Tapachula, Mexico: Spatial variation and response to historical insecticide use.
40  lethal concentrations at which 50% of the tadpoles
(1 time)
Chemistry
(1 time)
--- 2008 Effects of diazinon on larvae of the Asian common toad (Bufo melanostictus, Schneider 1799).
41  lethal concentrations capable of killing 50% of the test population
(1 time)
Bacteriology
(1 time)
CFU (1 time)
IPS-78 (1 time)
ITU (1 time)
1991 Formulation of a flowable liquid concentrate of Bacillus thuringiensis serotype H-14 spores and crystals as mosquito larvicide.
42  lethal concentrations needed to kill 50% of the larvae
(1 time)
Zoology
(1 time)
LT50 (1 time)
2016 Laboratory Evaluation of the Toxicity of Systemic Insecticides to Emerald Ash Borer Larvae.
43  lethal concentrations of 1503 ppm
(1 time)
Zoology
(1 time)
DMSO (1 time)
2008 Toxicity of extract of Magonia pubescens (Sapindales: Sapindaceae) St. Hil. to control the brown dog tick, Rhipicephalus sanguineus (Latreille) (Acari: Ixodidae).
44  Lethal concentrations of 50% for BDEO on C. macellaria
(1 time)
Biology
(1 time)
--- 2017 Insecticide activity of Baccharis dracunculifolia essential oil against Cochliomyia macellaria (Diptera: Calliphoridae).
45  lethal concentrations of ivermectin that killed 50
(1 time)
Tropical Medicine
(1 time)
MDA (1 time)
2017 Ivermectin susceptibility, sporontocidal effect, and inhibition of time to re-feed in the Amazonian malaria vector Anopheles darlingi.
46  lethal concentrations of substituted chalcones capable of killing 50
(1 time)
Toxicology
(1 time)
--- 2020 Larvicidal activity of substituted chalcones against Aedes aegypti (Diptera: Culicidae) and non-target organisms.
47  lethal concentrations required to eliminate the 50
(1 time)
Parasitology
(1 time)
EF (1 time)
2019 Effect of entomopathogenic native fungi from paddock soils against Rhipicephalus microplus larvae with different toxicological behaviors to acaricides.
48  lethal concentrations that cause death of 50
(1 time)
Toxicology
(1 time)
NPs (1 time)
qRT-PCR (1 time)
2020 Transcriptome alterations and genotoxic influences in zebrafish larvae after exposure to dissolved aluminum and aluminum oxide nanoparticles.
49  lethal concentrations, that kills 50% of exposed snails
(1 time)
Environmental Health
(1 time)
ALP (1 time)
AST (1 time)
F-ZnO (1 time)
2022 Molluscicidal and biochemical effects of green-synthesized F-doped ZnO nanoparticles against land snail Monacha cartusiana under laboratory and field conditions.
50  lethality assay, the 50% fatal concentrations
(1 time)
Biology
(1 time)
BPA (1 time)
LDPT (1 time)
NTDT (1 time)
2022 Silibinin and Naringenin against Bisphenol A-Induced Neurotoxicity in Zebrafish Model-Potential Flavonoid Molecules for New Drug Design, Development, and Therapy for Neurological Disorders.
51  lipid weight basis predicted to result in 50% kit mortality
(1 time)
Chemistry
(1 time)
PCBs (1 time)
PCDDs (1 time)
PCDFs (1 time)
2017 Use of polychlorinated biphenyl and toxic equivalent concentrations in scat from mink(Neovison vison) fed fish from the upper Hudson River to predict dietary and hepatic concentrations and health effects.
52  lower concentrations, i.e., concentration at which 50% is observed
(1 time)
Parasitology
(1 time)
ppm (1 time)
2019 Utilizing larvicidal and pupicidal efficacy of Eucalyptus and neem oil against Aedes mosquito: An approach for mosquito control.
53  lowest concentration at which 50% of the organisms died
(1 time)
Chemistry
(1 time)
--- 2002 Copper toxicity to larval Mercenaria mercenaria (hard clam).