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Abbreviation: Leu
Appearance Frequency: 511 time(s)
Long forms: 109

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Long Form No. Long Form Research Area Co-occurring Abbreviation PubMed/MEDLINE Info. (Year, Title)
leucine
(320 times)
Physiology
(53 times)
Val (72 times)
Ile (59 times)
Phe (44 times)
1970 Chromosomal location of the C gene involved in the biosynthesis of nicotinamide adenine dinucleotide in Escherichia coli K-12.
L-leucine
(49 times)
Chemistry
(9 times)
Phe (13 times)
Met (9 times)
Trp (6 times)
1977 Effect of maternal protein deprivation on the development of neonatal intestinal function in rats.
Leu-tRNA
(21 times)
Biochemistry
(10 times)
LeuRS (7 times)
Phe (4 times)
aaRSs (2 times)
1990 Significance of the third tRNA binding site, the E site, on E. coli ribosomes for the accuracy of translation: an occupied E site prevents the binding of non-cognate aminoacyl-tRNA to the A site.
leucyl-tRNA
(4 times)
Biochemistry
(2 times)
LeuRS (2 times)
CTD (1 time)
MtbLeuRS (1 time)
2007 An antifungal agent inhibits an aminoacyl-tRNA synthetase by trapping tRNA in the editing site.
leucylation of tRNA
(4 times)
Biochemistry
(4 times)
LeuRS (3 times)
Ser (3 times)
1996 The discriminator bases G73 in human tRNA(Ser) and A73 in tRNA(Leu) have significantly different roles in the recognition of aminoacyl-tRNA synthetases.
Leuconostoc
(3 times)
Nutritional Sciences
(1 time)
EPS (1 time)
LAB (1 time)
Lb (1 time)
2007 Changes in intestinal microbiota and humoral immune response following probiotic administration in brown trout (Salmo trutta).
LeuRS and tRNA
(3 times)
Biochemistry
(2 times)
LeuRS (2 times)
CTD (1 time)
MtbLeuRS (1 time)
2002 Leucyl-tRNA synthetase consisting of two subunits from hyperthermophilic bacteria Aquifex aeolicus.
control-region-like sequence and tRNA
(2 times)
Molecular Biology
(1 time)
Ile (1 time)
mtDNA (1 time)
1996 Gene rearrangements in snake mitochondrial genomes: highly concerted evolution of control-region-like sequences duplicated and inserted into a tRNA gene cluster.
L-(1-14C)leucine
(2 times)
Physiology
(2 times)
GIT (1 time)
HDHV (1 time)
KIC (1 time)
1982 In vivo leucine oxidation at rest and during two intensities of exercise.
10  leucine enkephalin
(2 times)
Physiology
(1 time)
MET (2 times)
CSF (1 time)
DYN (1 time)
1996 Relationship between vasopressin and opioids in hypoxia induced pial artery vasodilation.
11  leupeptin
(2 times)
Food
(1 time)
CatB (1 time)
GRh2 (1 time)
LF (1 time)
1998 [Cell to cell transfer of dense bodies induced by intracisternal infusion of leupeptin in rat cerebellum--quantitative and ultrastructural studies].
12  leuprolide
(2 times)
Endocrinology
(1 time)
Bus (1 time)
CC (1 time)
GnRH-a (1 time)
1992 Steroidogenesis in vitro of human granulosa-luteal cells pretreated in vivo with two gonadotropin releasing hormone analogs employing different protocols.
13  (alphabeta-LeuRS) catalyzes the hydrolytic editing of both mischarged tRNA
(1 time)
Biotechnology
(1 time)
--- 2005 Leucyl-tRNA synthetase from the ancestral bacterium Aquifex aeolicus contains relics of synthetase evolution.
14  (Asp-Ala-His-Lys-Ser-Glu-Val-Ala-), the carboxy terminus
(1 time)
Science
(1 time)
--- 1979 Fetal and adult albumins are indistinguishable by immunological and physicochemical criteria.
15  15N-leucine
(1 time)
Medicine
(1 time)
BCAA (1 time)
FHF (1 time)
Gln (1 time)
1997 A 15N GC/MS study of in vivo glutamine synthesis in liver failure rats.
16  226leucine
(1 time)
Geriatrics
(1 time)
EOAD (1 time)
PCR (1 time)
Phe (1 time)
2016 PSEN1 L226F mutation in a patient with early-onset Alzheimer's disease in Korea.
17  3H-leucine incorporation in proteins and in aminoacyl-tRNA
(1 time)
Biology
(1 time)
--- 1990 [Circadian rhythm of tRNA aminoacylation in hepatocyte culture].
18  5'-leader and 3'-trailer sequences as did pre-tRNAs
(1 time)
Cell Biology
(1 time)
--- 1988 Saccharomyces cerevisiae SUP53 tRNA gene transcripts are processed by mammalian cell extracts in vitro but are not processed in vivo.
19  Arg-Lys sequences to yield free
(1 time)
Biochemistry
(1 time)
--- 1983 Processing of prodynorphin at single and paired basic residues in porcine neurointermediate lobe.
20  clover-leaf structure except for tRNA
(1 time)
DNA, Mitochondrial
(1 time)
DHU (1 time)
2016 The complete mitochondrial genome of western Mediterranean mouse, Mus spretus (Rodentia: Muridae).
21  dansyl-leucine
(1 time)
Biochemistry
(1 time)
Asp (1 time)
NDA (1 time)
2008 Development of a novel capillary electrophoresis chemiluminescence system for amino acid analysis.
22  dynorphin-like immunoreactivity decreased in some neurons and that
(1 time)
Neurology
(1 time)
--- 1990 Localization of chemical messengers in magnocellular neurons of the hypothalamic supraoptic and paraventricular nuclei: an immunohistochemical study using experimental manipulations.
23  Gly-Leu, stabilized by two intramolecular
(1 time)
Biochemistry
(1 time)
AIB (1 time)
1993 Conformational difference between diastereomers of Dnp-Val-Aib-Gly-Leu-pNA studied by x-ray crystal analyses.
24  Gly-Leu-Leu-Thr-Gly
(1 time)
Biochemistry
(1 time)
--- 1991 Purification and characterization of cytochrome P-45014DM (lanosterol 14 alpha-demethylase) from pig liver microsomes.
25  hydrolysate-leucine
(1 time)
Nutritional Sciences
(1 time)
IR (1 time)
2014 Effects of whey protein and leucine supplementation on insulin resistance in non-obese insulin-resistant model rats.
26  Ile-Ile-Leu- Pro
(1 time)
Chemistry
(1 time)
Glu (1 time)
2011 Characterization of major zinc containing myonecrotic and procoagulant metalloprotease 'malabarin' from non lethal trimeresurus malabaricus snake venom with thrombin like activity: its neutralization by chelating agents.
27  L-(1-14C)leucine counts: uptake = E x
(1 time)
Endocrinology
(1 time)
--- 1988 Measurement of L-[1-14C]leucine kinetics in splanchnic and leg tissues in humans. Effect of amino acid infusion.
28  L-(4,5-3H)leucine
(1 time)
Medicine
(1 time)
IDDM (1 time)
KIC (1 time)
1986 Defective suppression by insulin of leucine-carbon appearance and oxidation in type 1, insulin-dependent diabetes mellitus. Evidence for insulin resistance involving glucose and amino acid metabolism.
29  L-leucine into the tRNA
(1 time)
Biochemistry
(1 time)
--- 1992 An enzymatic method for the estimation of L-leucine in rat blood.
30  laid the foundation for the NMR study of tRNA
(1 time)
Molecular Biology
(1 time)
--- 2011 1H, 15N chemical shift assignments of the imino groups in the base pairs of Escherichia coli tRNA(Leu) (CAG).
31  large number of different mutations is found in the tRNA
(1 time)
Biochemistry
(1 time)
--- 1998 Impairment of tRNA processing by point mutations in mitochondrial tRNA(Leu)(UUR) associated with mitochondrial diseases.
32  large ribosomal subunit and the tRNA
(1 time)
Biology
(1 time)
--- 1981 The characterization of the area of rat mitochondrial DNA containing the large ribosomal RNA gene.
33  last two residues flattened against the external surfaces
(1 time)
Allergy and Immunology
(1 time)
--- 1987 The binding of opioid peptides to the Mcg light chain dimer: flexible keys and adjustable locks.
34  layer that is immunoreactive with antisera against beta-endorphin
(1 time)
Allergy and Immunology
(1 time)
--- 1990 Neuropeptide-immunoreactive cells in human thymus.
35  lead ions in reaction mixture increase tRNA
(1 time)
Medicine
(1 time)
--- 2003 [Effects of lead ions on activities of tRNALeu and leucyl-tRNA synthetase of mouse liver].
36  Leu to tRNA
(1 time)
Biochemistry
(1 time)
LeuRS (1 time)
2002 Discrimination of tRNA(Leu) isoacceptors by the mutants of Escherichia coli leucyl-tRNA synthetase in editing.
37  Leuce Duby
(1 time)
Genomics
(1 time)
Aig (1 time)
DEGs (1 time)
MAPKs (1 time)
2018 Genome-Wide Transcriptome Analysis Reveals the Comprehensive Response of Two Susceptible Poplar Sections to Marssonina brunnea Infection.
38  leucine aminopeptidase
(1 time)
Environmental Health
(1 time)
AOB (1 time)
CHL (1 time)
IPU (1 time)
2018 Assessment of the impact of three pesticides on microbial dynamics and functions in a lab-to-field experimental approach.
39  leucine content within the HP diet
(1 time)
Biochemistry
(1 time)
Ala (1 time)
2013 Dietary L-leucine and L-alanine supplementation have similar acute effects in the prevention of high-fat diet-induced obesity.
40  leucine from tRNA
(1 time)
Biochemistry
(1 time)
aaRSs (1 time)
CP1 (1 time)
LeuRS (1 time)
2004 Molecular modeling study of the editing active site of Escherichia coli leucyl-tRNA synthetase: two amino acid binding sites in the editing domain.
41  leucine into non-cognate phenylalanine codons by mutant tRNAs
(1 time)
Biochemistry
(1 time)
--- 2000 Modification defect at anticodon wobble nucleotide of mitochondrial tRNAs(Leu)(UUR) with pathogenic mutations of mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes.
42  leucine specificity was contingent on the presence of the tRNA
(1 time)
Molecular Biology
(1 time)
Ser (2 times)
tRNAs (1 time)
2000 tRNA leucine identity and recognition sets.
43  leucine tRNA species, tRNA
(1 time)
Biochemistry
(1 time)
cmnm5Um (1 time)
1999 Modified nucleosides in the first positions of the anticodons of tRNA(Leu)4 and tRNA(Leu)5 from Escherichia coli.
44  leucine with tRNA
(1 time)
Molecular Biology
(1 time)
hcLeuRS (1 time)
LeuRSs (1 time)
ScLeuRS (1 time)
2014 A bridge between the aminoacylation and editing domains of leucyl-tRNA synthetase is crucial for its synthetic activity.
45  leucine, 1.1 x 10(-5)m; adenosine triphosphate, 6.5 x 10(-4)m; tRNA(I)
(1 time)
Bacteriology
(1 time)
tRNA (1 time)
1972 Leucyl-transfer ribonucleic acid synthetase from a wild-type and temperature-sensitive mutant of Salmonella typhimurium.
46  leucine, and tRNA
(1 time)
Biochemistry
(1 time)
--- 2005 The C-terminal appended domain of human cytosolic leucyl-tRNA synthetase is indispensable in its interaction with arginyl-tRNA synthetase in the multi-tRNA synthetase complex.
47  leucocyte numbers
(1 time)
Genetics
(1 time)
Bas (1 time)
EOS (1 time)
LYM (1 time)
2008 Quantitative trait loci for white blood cell numbers in swine.
48  leucyl isoacceptors tRNA
(1 time)
Molecular Biology
(1 time)
--- 2010 YibK is the 2'-O-methyltransferase TrmL that modifies the wobble nucleotide in Escherichia coli tRNA(Leu) isoacceptors.
49  leucyl tRNA from S. coelicolor, the bldA encoded tRNA
(1 time)
Molecular Biology
(1 time)
PCR (1 time)
1997 Use of polymerase chain reaction to identify a leucyl tRNA in Streptomyces coelicolor.
50  leucyl-tRNA synthase leads to a mischarged norvalyl-tRNA
(1 time)
Biology
(1 time)
--- 2013 Norvaline and norleucine may have been more abundant protein components during early stages of cell evolution.
51  leucyl-tRNA synthetase (E.C. 6.1.1.4) was specifically labelled with 3'-oxidized tRNA
(1 time)
Biology
(1 time)
--- 1987 Affinity labelling of E. coli leucyl-tRNA synthetase with 3'-oxidized tRNA(Leu).
52  leucyl-tRNA synthetase (LeuRS):tRNA
(1 time)
Science
(1 time)
Glu (1 time)
GluRS (1 time)
LeuRS (1 time)
2009 Dynamical networks in tRNA:protein complexes.
53  leucyl-tRNA synthetase by formation of a stable tRNA
(1 time)
Science
(1 time)
tRNA (1 time)
2007 An antifungal agent inhibits an aminoacyl-tRNA synthetase by trapping tRNA in the editing site.
54  leucyl-tRNA synthetase can edit the mischarged tRNA
(1 time)
Biochemistry
(1 time)
--- 2000 CP1 domain in Escherichia coli leucyl-tRNA synthetase is crucial for its editing function.
55  leucyl-tRNA synthetase complexed with the misaminoacylated tRNA
(1 time)
Biotechnology
(1 time)
MD (1 time)
MMs (1 time)
QMs (1 time)
2012 Biological applications of hybrid quantum mechanics/molecular mechanics calculation.
56  leucyl-tRNA synthetase recognizes tRNA
(1 time)
Molecular Biology
(1 time)
--- 1993 Recognition nucleotides of Escherichia coli tRNA(Leu) and its elements facilitating discrimination from tRNASer and tRNA(Tyr).
57  leucyl-tRNA synthetase with 3'-oxidized tRNA
(1 time)
Biology
(1 time)
--- 1987 Affinity labelling of E. coli leucyl-tRNA synthetase with 3'-oxidized tRNA(Leu).
58  leucyl-tRNA synthetases with archaeal tRNA binding domains that distinguish tRNA
(1 time)
Biochemistry
(1 time)
--- 2014 Coexistence of bacterial leucyl-tRNA synthetases with archaeal tRNA binding domains that distinguish tRNA(Leu) in the archaeal mode.
59  leucyl-tRNA, tRNA
(1 time)
Molecular Biology
(1 time)
--- 2014 The determination of tRNALeu recognition nucleotides for Escherichia coli L/F transferase.
60  leucylation of E. coli tRNA
(1 time)
Biochemistry
(1 time)
--- 2003 The processing of human mitochondrial leucyl-tRNA synthetase in the insect cells.
61  leuprolide acetate
(1 time)
Endocrinology
(1 time)
CPA (1 time)
TE (1 time)
2016 Cyproterone acetate vs leuprolide acetate in combination with transdermal oestradiol in transwomen: a comparison of safety and effectiveness.
62  LeuRS (hcLeuRS) and tRNA
(1 time)
Biochemistry
(1 time)
hcLeuRS (1 time)
LeuRS (1 time)
tRNA (1 time)
2011 Modular pathways for editing non-cognate amino acids by human cytoplasmic leucyl-tRNA synthetase.
63  LeuRS (LeuRSTT) with tRNA
(1 time)
Molecular Biology
(1 time)
LeuRS (1 time)
2005 The crystal structure of leucyl-tRNA synthetase complexed with tRNALeu in the post-transfer-editing conformation.
64  LeuRS (MtbLeuRS) and studied the effects on tRNA
(1 time)
Biochemistry
(1 time)
CTD (1 time)
LeuRS (1 time)
MtbLeuRS (1 time)
2013 Crucial role of the C-terminal domain of Mycobacterium tuberculosis leucyl-tRNA synthetase in aminoacylation and editing.
65  LeuRS alphabeta plays an important role in minihelix
(1 time)
Biochemistry
(1 time)
LeuRS (1 time)
2006 Split leucine-specific domain of leucyl-tRNA synthetase from the hyperthermophilic bacterium Aquifex aeolicus.
66  LeuRS by covalently trapping tRNA
(1 time)
Biochemistry
(1 time)
LeuRS (1 time)
2015 Analysis of the Resistance Mechanism of a Benzoxaborole Inhibitor Reveals Insight into the Leucyl-tRNA Synthetase Editing Mechanism.
67  LeuRS can mischarge tRNA
(1 time)
Biochemistry
(1 time)
LeuRS (1 time)
2002 Discrimination of tRNA(Leu) isoacceptors by the mutants of Escherichia coli leucyl-tRNA synthetase in editing.
68  LeuRS deacylates the mischarged Ile-tRNA
(1 time)
Biochemistry
(1 time)
--- 2006 Crystal structures of the editing domain of Escherichia coli leucyl-tRNA synthetase and its complexes with Met and Ile reveal a lock-and-key mechanism for amino acid discrimination.
69  LeuRS editing active site which requires the presence of tRNA
(1 time)
Natural Science Disciplines
(1 time)
LeuRS (1 time)
SpLeuRS (1 time)
2013 Discovery of a potent benzoxaborole-based anti-pneumococcal agent targeting leucyl-tRNA synthetase.
70  LeuRS for the anticodon stem of tRNA
(1 time)
Biochemistry
(1 time)
LeuRSs (1 time)
2015 Modulation of Aminoacylation and Editing Properties of Leucyl-tRNA Synthetase by a Conserved Structural Module.
71  LeuRS mutants charge tRNA
(1 time)
Biochemistry
(1 time)
LeuRS (1 time)
2009 Defects in transient tRNA translocation bypass tRNA synthetase quality control mechanisms.
72  LeuRS recognition of tRNA
(1 time)
Molecular Biology
(1 time)
LeuRS (1 time)
2005 The crystal structure of leucyl-tRNA synthetase complexed with tRNALeu in the post-transfer-editing conformation.
73  LeuRS system, the anticodon of tRNA
(1 time)
Biochemistry
(1 time)
LeuRS (1 time)
2004 Leucyl-tRNA synthetase from the hyperthermophilic bacterium Aquifex aeolicus recognizes minihelices.
74  LeuRS with tRNA
(1 time)
Biochemistry
(1 time)
CP1 (1 time)
GlLeuRS (1 time)
LeuRS (1 time)
2009 Two tyrosine residues outside the editing active site in Giardia lamblia leucyl-tRNA synthetase are essential for the post-transfer editing.
75  LeuRS x tRNA
(1 time)
Biochemistry
(1 time)
Ile (2 times)
LeuRS (1 time)
Thr (1 time)
2007 The C-terminal domain of the archaeal leucyl-tRNA synthetase prevents misediting of isoleucyl-tRNA(Ile).
76  LeuRS-A can discriminate between the two isoacceptors of tRNA
(1 time)
Biochemistry
(1 time)
CP1 (1 time)
LeuRS (1 time)
1999 Discrimination of tRNALeu isoacceptors by the insertion mutant of Escherichia coli leucyl-tRNA synthetase.
77  LeuRS-B can catalyze mischarging of tRNA
(1 time)
Biochemistry
(1 time)
--- 2000 CP1 domain in Escherichia coli leucyl-tRNA synthetase is crucial for its editing function.
78  LeuRS-intrinsic editing domain, the fidelity of tRNA
(1 time)
Cell Biology
(1 time)
EGOC (1 time)
LeuRS (1 time)
TORC1 (1 time)
2012 Leucyl-tRNA synthetase controls TORC1 via the EGO complex.
79  LeuRSs catalyzed the aminoacylation of tRNA
(1 time)
Biochemistry
(1 time)
LeuRS (1 time)
1999 The peptide bond between E292-A293 of Escherichia coli leucyl-tRNA synthetase is essential for its activity.
80  LeuRSs have been reported to recognize tRNA
(1 time)
Biochemistry
(1 time)
CaLeuRS (1 time)
CTD (1 time)
LeuRS (1 time)
2016 C-terminal Domain of Leucyl-tRNA Synthetase from Pathogenic Candida albicans Recognizes both tRNASer and tRNALeu.
81  LeuRSs with respect to tRNA
(1 time)
Biochemistry
(1 time)
CP1 (1 time)
LeuRS (1 time)
2009 A unique insertion in the CP1 domain of Giardia lamblia leucyl-tRNA synthetase.
82  level of mature tRNA
(1 time)
Biochemistry
(1 time)
BA (1 time)
1996 Cucumber chloroplast trnL(CAA) gene: nucleotide sequence and in vivo expression analysis in etiolated cucumber seedlings treated with benzyladenine and light.
83  levels decreased according to an exponential curve
(1 time)
Pediatrics
(1 time)
CECRT (1 time)
2005 Kinetic modeling of plasma leucine levels during continuous venovenous extracorporeal removal therapy in neonates with maple syrup urine disease.
84  levels of glucose and insulin
(1 time)
Endocrinology
(1 time)
CHO (1 time)
mTOR (1 time)
PI 3-kinase (1 time)
2005 Leucine reduces the duration of insulin-induced PI 3-kinase activity in rat skeletal muscle.
85  levels of immunoreactive
(1 time)
Biochemistry
(1 time)
--- 1985 A general procedure for analysis of proenkephalin B derived opioid peptides.
86  lichens by using the tRNA
(1 time)
Microbiology
(1 time)
--- 1998 Sequence variation of the tRNA(Leu) intron as a marker for genetic diversity and specificity of symbiotic cyanobacteria in some lichens.
87  light sensitivity; the mutants Trp-126----Phe
(1 time)
Biochemistry
(1 time)
Ala (1 time)
1992 Light-stable rhodopsin. II. An opsin mutant (TRP-265----Phe) and a retinal analog with a nonisomerizable 11-cis configuration form a photostable chromophore.
88  likely to require the tRNA
(1 time)
Molecular Biology
(1 time)
nt (1 time)
ORF (1 time)
tsp (1 time)
1990 Transcriptional and translational features of a sporulation gene of Streptomyces griseus.
89  limitation resulted in a broad response. tRNA
(1 time)
Bacteriology
(1 time)
--- 2008 Global responses of Methanococcus maripaludis to specific nutrient limitations and growth rate.
90  linked series of CUG
(1 time)
Biochemistry
(1 time)
ASCT2 (1 time)
2001 Truncated forms of the dual function human ASCT2 neutral amino acid transporter/retroviral receptor are translationally initiated at multiple alternative CUG and GUG codons.
91  lipase consensus sequence Gly-X
(1 time)
Biochemistry
(1 time)
cPLA2 (1 time)
PLB (1 time)
1994 Serine 228 is essential for catalytic activities of 85-kDa cytosolic phospholipase A2.
92  liver, kidney, and heart as well as diminution of tRNA
(1 time)
Medicine
(1 time)
--- 2008 Subacute effects of cadmium and zinc ions on protein synthesis and cell death in mouse liver.
93  liverwort Blasia pusilla, was examined using the tRNA
(1 time)
Microbiology
(1 time)
--- 2001 Genetic diversity of Nostoc symbionts endophytically associated with two bryophyte species.
94  localization of immunoreactive dynorphin(1-8)
(1 time)
Neurology
(1 time)
--- 1987 A re-examination of the localization of immunoreactive dynorphin(1-8), [Leu]enkephalin and [Met]enkephalin in the rat neurohypophysis.
95  localized; does immunoreactive
(1 time)
Neurology
(1 time)
--- 1987 A re-examination of the localization of immunoreactive dynorphin(1-8), [Leu]enkephalin and [Met]enkephalin in the rat neurohypophysis.
96  loci of neuronal systems immunoreactive for beta-endorphin
(1 time)
Biochemistry
(1 time)
--- 1983 Comparative distribution of opiate receptors and three opioid peptide neuronal systems in rhesus monkey central nervous system.
97  long variable-arm (V-arm) structures form in tRNA
(1 time)
Molecular Biology
(1 time)
nov-tRNAs (1 time)
tRNA (1 time)
V-arm (1 time)
2016 Expansion of Noncanonical V-Arm-Containing tRNAs in Eukaryotes.
98  low availability of intracellular tRNA
(1 time)
Biochemistry
(1 time)
--- 1993 Effect of a rare leucine codon, TTA, on expression of a foreign gene in Streptomyces lividans.
99  Low concentrations of zinc ions in reaction mixture increase tRNA
(1 time)
Medicine
(1 time)
--- 2004 The effects of zinc ions on activities of tRNALeu and leucyl-tRNA synthetase of mice liver.
100  low efficiency, but native tRNA
(1 time)
Molecular Biology
(1 time)
--- 1997 Only one nucleotide insertion to the long variable arm confers an efficient serine acceptor activity upon Saccharomyces cerevisiae tRNA(Leu) in vitro.