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Abbreviation: MAPK
Appearance Frequency: 17539 time(s)
Long forms: 41

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Long Form No. Long Form Research Area Co-occurring Abbreviation PubMed/MEDLINE Info. (Year, Title)
mitogen-activated protein kinase
(17133 times)
Biochemistry
(2595 times)
ERK (2399 times)
JNK (1495 times)
PI3K (1130 times)
1992 Mitogen-activated-protein-kinase-catalyzed phosphorylation of microtubule-associated proteins, microtubule-associated protein 2 and microtubule-associated protein 4, induces an alteration in their function.
MAP kinase
(343 times)
Molecular Biology
(82 times)
MAP (27 times)
MAPKK (19 times)
PI3K (17 times)
1993 Inhibition of the EGF-activated MAP kinase signaling pathway by adenosine 3',5'-monophosphate.
microtubule-associated protein kinase
(12 times)
Biochemistry
(4 times)
MEK (2 times)
BDNF (1 time)
CT (1 time)
1993 Direct stimulation by tyrosine phosphorylation of microtubule-associated protein (MAP) kinase activity by granulocyte-macrophage colony-stimulating factor in human neutrophils.
mitogen-activated PK
(5 times)
Botany
(1 time)
PK (3 times)
TK (2 times)
2-APB (1 time)
2001 Proadrenomedullin-derived peptides as autocrine-paracrine regulators of cell growth.
Mitogen activated phosphokinase
(3 times)
Medicine
(2 times)
COX-2 (1 time)
GA (1 time)
HO-1 (1 time)
2001 Peroxynitrite induces neuronal cell death in aging and age-associated disorders: A review.
mitogen-activated kinase protein
(3 times)
Neoplasms
(2 times)
AP-1 (1 time)
CML (1 time)
GA (1 time)
1999 p50(cdc37) acting in concert with Hsp90 is required for Raf-1 function.
mitogen-activated phosphorylated kinase
(3 times)
Molecular Biology
(1 time)
ALA (1 time)
CM (1 time)
ICAM-1 (1 time)
2005 The nitrogen mustard melphalan activates mitogen-activated phosphorylated kinases (MAPK), nuclear factor-kappaB and inflammatory response in lung epithelial cells.
Ras-MAP kinase
(3 times)
Neurology
(1 time)
7 DIV (1 time)
CREB (1 time)
phospho-CREB (1 time)
1997 v-src-induced cell shape changes in rat fibroblasts require new gene transcription and precede loss of focal adhesions.
flk-1-mediated activation of p38
(2 times)
Science
(1 time)
--- 2006 VEGF, a prosurvival factor, acts in concert with TGF-beta1 to induce endothelial cell apoptosis.
10  ERK-MAPK
(1 time)
Cell Biology
(1 time)
mTORC1 (1 time)
2008 Deconstructing feedback-signaling networks to improve anticancer therapy with mTORC1 inhibitors.
11  interleukin-1beta-mitogen-activated protein kinase
(1 time)
Allergy and Immunology
(1 time)
EPS (1 time)
FLSs (1 time)
2015 Effect of ebosin on modulating interleukin-1beta-induced inflammatory responses in rat fibroblast-like synoviocytes.
12  IRS-2-mediated PI 3-kinase activation as well as p42
(1 time)
Physiology
(1 time)
2-DG (1 time)
IRS (1 time)
PI 3-kinase (1 time)
1999 TNF-alpha impairs insulin signaling and insulin stimulation of glucose uptake in C2C12 muscle cells.
13  many efforts to develop drugs that target the RAS-RAF-MEK-ERK
(1 time)
Clinical Medicine
(1 time)
NSCLC (1 time)
2015 KRAS mutant lung cancer: progress thus far on an elusive therapeutic target.
14  MAP/Erk kinase
(1 time)
Allergy and Immunology
(1 time)
IL (1 time)
1996 Interleukin-7 induces T cell proliferation in the absence of Erk/MAP kinase activity.
15  MAPK-activated protein kinase-2, a well-known downstream effector of p38
(1 time)
Biochemistry
(1 time)
--- 2000 Activation of p38 mitogen-activated protein kinase and mitochondrial Ca(2+)-mediated oxidative stress are essential for the enhanced expression of grp78 induced by the protein phosphatase inhibitors okadaic acid and calyculin A.
16  MAPK/ERK
(1 time)
Endocrinology
(1 time)
MEK (1 time)
2012 The Akt inhibitor MK2206 synergizes, but perifosine antagonizes, the BRAF(V600E) inhibitor PLX4032 and the MEK1/2 inhibitor AZD6244 in the inhibition of thyroid cancer cells.
17  MAPKAPK-2, that lie upstream and downstream of p38
(1 time)
Biochemistry
(1 time)
HEK (1 time)
2008 Activation of p38(MAPK) mediates the angiostatic effect of the chemokine receptor CXCR3-B.
18  MAPkinases ERK-1/-2, p38
(1 time)
Pulmonary Medicine
(1 time)
ERK (1 time)
T-bet (1 time)
2007 IL-12-induced T-bet expression and IFNgamma release in lymphocytes from asthmatics--role of MAPkinases ERK-1/-2, p38(MAPK) and effect of dexamethasone.
19  may promote NF-kappaB signaling via activation of mitogen-activated kinase
(1 time)
Cell Biology
(1 time)
BDNF (1 time)
IKK (1 time)
NF-kappaB (1 time)
2008 Ankyrin-rich membrane spanning protein plays a critical role in nuclear factor-kappa B signaling.
20  mechanism for TGFbeta and Alk5-dependent Erk1/2
(1 time)
Cell Biology
(1 time)
--- 2015 Endocytic deficiency induced by ITSN-1s knockdown alters the Smad2/3-Erk1/2 signaling balance downstream of Alk5.
21  mechanism for TPA-induced ERK
(1 time)
Medicine
(1 time)
AS (1 time)
ODN (1 time)
TPA (1 time)
2005 Activation of protein kinase C alpha is required for TPA-triggered ERK (MAPK) signaling and growth inhibition of human hepatoma cell HepG2.
22  mediated by NADPH oxidase involving PI 3-K and p42/44
(1 time)
Pharmacology
(1 time)
11-keto-BAs (1 time)
AA (1 time)
LT (1 time)
2004 Coupling of boswellic acid-induced Ca2+ mobilisation and MAPK activation to lipid metabolism and peroxide formation in human leucocytes.
23  MEK-1, prevented the dual phosphorylation of p42/44
(1 time)
Biochemistry
(1 time)
HGF/SF (1 time)
PtdIns3K (1 time)
Rama (1 time)
2001 Hepatocyte growth factor/scatter factor stimulates migration of rat mammary fibroblasts through both mitogen-activated protein kinase and phosphatidylinositol 3-kinase/Akt pathways.
24  MEK-ERK1/2-pathway independent of p38
(1 time)
Cell Biology
(1 time)
MK (1 time)
OSMR (1 time)
SOCS (1 time)
2015 Oncostatin M regulates SOCS3 mRNA stability via the MEK-ERK1/2-pathway independent of p38(MAPK)/MK2.
25  members of the 'mitogen-activated protein kinase
(1 time)
Neoplasms
(1 time)
TGCT (1 time)
2004 Cisplatin-induced apoptosis in human malignant testicular germ cell lines depends on MEK/ERK activation.
26  microkeratome-assisted posterior keratoplasty
(1 time)
Ophthalmology
(1 time)
CH (1 time)
CRF (1 time)
HTH PK (1 time)
2015 [Evaluation of corneal biomechanics before and after up-to-date keratoplasty in patients with bullous keratopathy].
27  Microwave-assisted synthesis of 5-aminopyrazol-4-yl ketones and the p38
(1 time)
Biochemistry
(1 time)
--- 2008 Microwave-assisted synthesis of 5-aminopyrazol-4-yl ketones and the p38(MAPK) inhibitor RO3201195 for study in Werner syndrome cells.
28  migration through a G(i)-linked and a PI3-K coupled, p38
(1 time)
General Surgery
(1 time)
EGF (1 time)
PI3K (1 time)
S1P (1 time)
2003 Sphingosine-1-phosphate stimulates smooth muscle cell migration through galpha(i)- and pi3-kinase-dependent p38(MAPK) activation.
29  migration through galpha(i)- and pi3-kinase-dependent p38
(1 time)
General Surgery
(1 time)
EGF (1 time)
PI3K (1 time)
S1P (1 time)
2003 Sphingosine-1-phosphate stimulates smooth muscle cell migration through galpha(i)- and pi3-kinase-dependent p38(MAPK) activation.
30  mitogen protein-activated kinase
(1 time)
Neurology
(1 time)
IL (1 time)
LDH (1 time)
MMP-9 (1 time)
2011 Mild stretch-induced injury increases susceptibility to interleukin-1beta-induced release of matrix metalloproteinase-9 from astrocytes.
31  mitogen-activated/extracellular signal-regulated protein kinase
(1 time)
Chemistry
(1 time)
IGF-I (1 time)
IRS-2 (1 time)
2001 Inhibition of insulin-like growth factor-1 receptor and IRS-2 signaling by ethanol in SH-SY5Y neuroblastoma cells.
32  Mitotic-Associated Protein Kinase
(1 time)
Biotechnology
(1 time)
ERK7 (1 time)
TORC1 (1 time)
2011 ERK7 is a negative regulator of protein secretion in response to amino-acid starvation by modulating Sec16 membrane association.
33  MKP-1 was a target in vivo and in vitro for p42
(1 time)
Science
(1 time)
MAP (1 time)
MKP (1 time)
1999 Reduced MAP kinase phosphatase-1 degradation after p42/p44MAPK-dependent phosphorylation.
34  MKP-1's intrinsic ability to dephosphorylate p44
(1 time)
Science
(1 time)
MAP (1 time)
MKP (1 time)
1999 Reduced MAP kinase phosphatase-1 degradation after p42/p44MAPK-dependent phosphorylation.
35  modulation of PKC-alpha and -beta₂-mitogen-activated protein kinase
(1 time)
Chemistry
(1 time)
ERK (1 time)
PKC (1 time)
STZ (1 time)
2012 Curcumin prevents diabetic cardiomyopathy in streptozotocin-induced diabetic rats: possible involvement of PKC-MAPK signaling pathway.
36  modulation via ROS-dependent ASK1-p38
(1 time)
Neurology
(1 time)
ASK1 (1 time)
beta-Ecd (1 time)
DN (1 time)
2016 beta-Ecdysterone Protects SH-SY5Y Cells Against 6-Hydroxydopamine-Induced Apoptosis via Mitochondria-Dependent Mechanism: Involvement of p38(MAPK)-p53 Signaling Pathway.
37  multiple factors of the KIT-RAS-RAF-MEK-ERK
(1 time)
Neoplasms
(1 time)
AML (1 time)
2018 Endogenous Tumor Suppressor microRNA-193b: Therapeutic and Prognostic Value in Acute Myeloid Leukemia.
38  mutant kinase inhibited IL-1beta-induced p38
(1 time)
Biochemistry
(1 time)
IL-1beta (1 time)
iNOS (1 time)
NO (1 time)
1999 Both p38alpha(MAPK) and JNK/SAPK pathways are important for induction of nitric-oxide synthase by interleukin-1beta in rat glomerular mesangial cells.
39  myelin basic protein kinases
(1 time)
Biochemistry
(1 time)
--- 1998 Stimulation of MAP kinase and S6 kinase by vanadium and selenium in rat adipocytes.
40  p38-MAP kinase
(1 time)
Endocrinology
(1 time)
MAP (1 time)
2001 Hyperglycemia activates p53 and p53-regulated genes leading to myocyte cell death.
41  pheromone-mediated-mitogen activated protein kinase
(1 time)
Cell Biology
(1 time)
--- 1998 Saccharomyces cerevisiae STE11 may contribute to the stabilities of a scaffold protein, STE5, in the pheromone signaling pathway.