| 1 |
murine double minute 2
(908 times)
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Neoplasms
(282 times)
|
OR (34 times)
CI (30 times)
SNP (26 times)
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1993 The p53-binding protein MDM2 gene is differentially expressed in human breast carcinoma.
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| 2 |
MDM2 proto-oncogene
(9 times)
|
Biochemistry
(4 times)
|
ATM (1 time)
CALB1 (1 time)
CHX (1 time)
|
2017 The involvement of E6, p53, p16, MDM2 and Gal-3 in the clinical outcome of patients with cervical cancer.
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| 3 |
MDM2 oncogene, E3 ubiquitin protein ligase
(5 times)
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Neoplasms
(3 times)
|
DEGs (3 times)
PPI (3 times)
GO (2 times)
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2014 MDM2 oncogene, E3 ubiquitin protein ligase T309G polymorphism and risk of oesophageal or gastric cancer: meta-analysis of 15 studies.
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| 4 |
mouse 3T3 cell double minute 2
(5 times)
|
Reproductive Medicine
(2 times)
|
Akt (2 times)
TRP53 (2 times)
cGAS (1 time)
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2008 Preimplantation embryo development in the mouse requires the latency of TRP53 expression, which is induced by a ligand-activated PI3 kinase/AKT/MDM2-mediated signaling pathway.
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| 5 |
Mdm2 p53 binding protein homolog
(4 times)
|
Cell Biology
(1 time)
|
2AA (1 time)
Aen (1 time)
ATM (1 time)
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2010 Gene expression following ionising radiation: identification of biomarkers for dose estimation and prediction of individual response.
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| 6 |
MDM2 protein, p76
(3 times)
|
Molecular Biology
(1 time)
|
ERalpha (1 time)
UTRs (1 time)
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2000 p76(MDM2) inhibits the ability of p90(MDM2) to destabilize p53.
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| 7 |
murine double mutant 2
(3 times)
|
Biology
(2 times)
|
I3C (1 time)
NBs (1 time)
NSCLC (1 time)
|
2013 hsa-miR29b, a critical downstream target of non-canonical Wnt signaling, plays an anti-proliferative role in non-small cell lung cancer cells via targeting MDM2 expression.
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| 8 |
mouse double minute gene number 2
(2 times)
|
Biochemistry
(2 times)
|
SCYL1-BP1 (2 times)
Pirh2 (1 time)
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2010 A newly identified Pirh2 substrate SCYL1-BP1 can bind to MDM2 and accelerate MDM2 self-ubiquitination.
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| 9 |
L-Mdm2 expression and enhanced p90
(1 time)
|
Biochemistry
(1 time)
|
---
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2004 PTEN regulates Mdm2 expression through the P1 promoter.
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| 10 |
main inhibitors of p53, hMDM2
(1 time)
|
Neoplasms
(1 time)
|
---
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2011 Oncogenic functions of hMDMX in in vitro transformation of primary human fibroblasts and embryonic retinoblasts.
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| 11 |
Mdm2 gene codes, in addition to the full-length p90
(1 time)
|
Molecular Biology
(1 time)
|
---
|
2010 Regulation of MDM4 (MDMX) function by p76(MDM2): a new facet in the control of p53 activity.
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| 12 |
mdm2 gene, p76
(1 time)
|
Biochemistry
(1 time)
|
---
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2000 p76(MDM2) inhibits the ability of p90(MDM2) to destabilize p53.
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| 13 |
mdm2 gene, whose product
(1 time)
|
Pathology
(1 time)
|
---
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2000 Amplification and overexpression of mdm2 gene in ependymomas.
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| 14 |
MDM2 homolog
(1 time)
|
Biochemistry
(1 time)
|
5-HT1ARs (1 time)
GPCRs (1 time)
N2A (1 time)
|
2019 Acute ethanol exposure reduces serotonin receptor 1A internalization by increasing ubiquitination and degradation of β-arrestin2.
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| 15 |
mdm2 mRNA and p90
(1 time)
|
Molecular Biology
(1 time)
|
TCR (1 time)
UV (1 time)
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2001 Defects in transcription coupled repair interfere with expression of p90(MDM2) in response to ultraviolet light.
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| 16 |
mdm2 mRNA that can encode p76
(1 time)
|
Biochemistry
(1 time)
|
---
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2000 p76(MDM2) inhibits the ability of p90(MDM2) to destabilize p53.
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| 17 |
mdm2 oncogene encodes p90
(1 time)
|
Biochemistry
(1 time)
|
---
|
2000 p76(MDM2) inhibits the ability of p90(MDM2) to destabilize p53.
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| 18 |
MDM2 proteins, including the inhibitor of p53, p90
(1 time)
|
Molecular Biology
(1 time)
|
---
|
2001 Purification of a fragment of MDM2 for production of polyclonal antisera.
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| 19 |
MDM2 SNP309
(1 time)
|
Brain
(1 time)
|
---
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2008 Influence of MDM2 SNP309 alone or in combination with the TP53 R72P polymorphism in oligodendroglial tumors.
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| 20 |
MDM2-FL
(1 time)
|
Neoplasms
(1 time)
|
---
|
2020 MDM2-C Functions as an E3 Ubiquitin Ligase.
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| 21 |
mouse double minute 2 oncogene E3 ubiquitin protein ligase
(1 time)
|
Neoplasms
(1 time)
|
DLBCL (2 times)
Bcl-2 (1 time)
CCND1 (1 time)
|
2014 Prevalence and clinical implications of cyclin D1 expression in diffuse large B-cell lymphoma (DLBCL) treated with immunochemotherapy: a report from the International DLBCL Rituximab-CHOP Consortium Program.
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| 22 |
mouse double minute 2 repressor
(1 time)
|
Medicine
(1 time)
|
TYP (1 time)
UQCRC2 (1 time)
|
2013 Nutlin-3a decreases male fertility via UQCRC2.
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| 23 |
mouse double minute-2 homolog protein
(1 time)
|
Physiological Phenomena
(1 time)
|
Per2 (1 time)
|
2020 A Systems Biology Approach Identifies Hidden Regulatory Connections Between the Circadian and Cell-Cycle Checkpoints.
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| 24 |
murine double minute 2 E3 ubiquitin ligase
(1 time)
|
Medicine
(1 time)
|
APF (1 time)
as-APF (1 time)
IC/PBS (1 time)
|
2012 A synthetic form of frizzled 8-associated antiproliferative factor enhances p53 stability through USP2a and MDM2.
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| 25 |
murine double minute 2 gene product, p90
(1 time)
|
Molecular Biology
(1 time)
|
---
|
2001 Purification of a fragment of MDM2 for production of polyclonal antisera.
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| 26 |
nucleolus-ARF-murine double minute 2
(1 time)
|
Cell Biology
(1 time)
|
ARF (1 time)
GLTSCR2 (1 time)
|
2012 Nucleolar protein GLTSCR2 stabilizes p53 in response to ribosomal stresses.
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