| 1 |
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
(3765 times)
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Neurology
(1653 times)
|
PD (1348 times)
DA (539 times)
TH (397 times)
|
1983 Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis.
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| 2 |
membrane permeability transition pore
(22 times)
|
Molecular Biology
(4 times)
|
ROS (6 times)
CypD (4 times)
cyt c (2 times)
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2007 A novel mitochondrial matrix serine/threonine protein phosphatase regulates the mitochondria permeability transition pore and is essential for cellular survival and development.
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| 3 |
MPT pore
(6 times)
|
Neurology
(2 times)
|
MPT (5 times)
ANT (2 times)
CsA (2 times)
|
2009 Drugs targeting the mitochondrial pore act as cytotoxic and cytostatic agents in temozolomide-resistant glioma cells.
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| 4 |
mitochondrial permeability pore
(5 times)
|
Metabolism
(2 times)
|
ALS (2 times)
ER (1 time)
GSK3beta (1 time)
|
2004 A unique pathway of cardiac myocyte death caused by hypoxia-acidosis.
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| 5 |
multiple tandem forward primers and a common reverse primer
(4 times)
|
Hematology
(2 times)
|
G6PD (3 times)
PCR (2 times)
G871A (1 time)
|
1999 Molecular basis of glucose-6-phosphate dehydrogenase deficiency among Filipinos.
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| 6 |
calcium-induced permeability transition pore
(2 times)
|
Physiology
(1 time)
|
ATP (1 time)
IS (1 time)
|
2011 Mitochondrial KATP channels participate in the limitation of infarct size by cariporide.
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| 7 |
methyl-4-phenylpyridine
(2 times)
|
Neurology
(1 time)
|
BG (1 time)
HPLC (1 time)
PD (1 time)
|
1995 Neuronal changes in the substantia nigra with aging: a Golgi study.
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| 8 |
MPTP-injected
(2 times)
|
Histocytochemistry
(1 time)
|
DHA (4 times)
PD (2 times)
SN (2 times)
|
2016 The protective mechanism of docosahexaenoic acid in mouse model of Parkinson: The role of hemeoxygenase.
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| 9 |
1,2,3,6-tetrahydro-1-methyl-4-phenylpyridine
(1 time)
|
Neurology
(1 time)
|
GC-MS (1 time)
|
1998 Environmental MPTP as a factor in the aetiology of Parkinson's disease?
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| 10 |
1,2,3,6-tetrahydro-1-methyl-4-phenylpyridine hydrochloride
(1 time)
|
Neurology
(1 time)
|
DA (1 time)
mTOR (1 time)
PD (1 time)
|
2011 Nucleolar disruption in dopaminergic neurons leads to oxidative damage and parkinsonism through repression of mammalian target of rapamycin signaling.
|
| 11 |
1-methyl-4-(2'-methylphenyl)-1,2,3,6-tetrahydrophine
(1 time)
|
Medicine
(1 time)
|
FTD (1 time)
PGRN (1 time)
|
2012 Progranulin deficiency promotes neuroinflammation and neuron loss following toxin-induced injury.
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| 12 |
many dopaminergic cells of the SNc and retina from parkinsonian
(1 time)
|
Parkinson Disease
(1 time)
|
SNc (1 time)
TH (1 time)
|
2013 Saffron pre-treatment offers neuroprotection to Nigral and retinal dopaminergic cells of MPTP-Treated mice.
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| 13 |
mean pulmonary trunk pressure
(1 time)
|
Medicine
(1 time)
|
---
|
2004 [Characterization of arrhythmia in pulmonary hypertension in patients with bronchial obstructive diseases].
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| 14 |
membrane potential and mitochondrial transition pore opening
(1 time)
|
Biochemistry
(1 time)
|
eNOS and iNOS (1 time)
hCG (1 time)
HUVEC (1 time)
|
2015 Human Chorionic Gonadotropin Protects Vascular Endothelial Cells from Oxidative Stress by Apoptosis Inhibition, Cell Survival Signalling Activation and Mitochondrial Function Protection.
|
| 15 |
metabolic profiling in the SN and STR of 1-methyl-1,2,3,6-tetrahydropyridine
(1 time)
|
Diagnostic Imaging
(1 time)
|
PD (1 time)
SN (1 time)
STR (1 time)
|
2017 Neurometabolic profiles of the substantia nigra and striatum of MPTP-intoxicated common marmosets: An in vivo proton MRS study at 9.4T.
|
| 16 |
mitochondrial calcium retention capacity, indicating decreased permeability transition pore
(1 time)
|
Drug Therapy
(1 time)
|
---
|
2019 Mitochondrial Complex I Inhibition by Metformin Limits Reperfusion Injury.
|
| 17 |
mitochondrial susceptibility to calcium-induced permeability transition pore
(1 time)
|
Toxicology
(1 time)
|
MDA (1 time)
SH (1 time)
SOD (1 time)
|
2012 In vitro salicylate does not further impair aging-induced brain mitochondrial dysfunction.
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| 18 |
modulation of sensitivity ofmitochondnal permeability transition pore
(1 time)
|
Physiology
(1 time)
|
NO (1 time)
NOS (1 time)
|
2009 [No-dependent modulation of the sensitivity of the mitochondrial permeability transition pore opening under ischemia-reperfusion of the isolated heart].
|
| 19 |
monkey unilaterally lesioned with 4-phenyl-1,2,3,6-tetrahydropyridine hydrochloride
(1 time)
|
Diagnostic Imaging
(1 time)
|
---
|
1996 Mapping drug-induced changes in cerebral R2* by Multiple Gradient Recalled Echo functional MRI.
|
| 20 |
more susceptible to neurotoxic effects of 1,2,3,6-tetrahydropyridine
(1 time)
|
Neurology
(1 time)
|
DA (1 time)
|
1996 Changes induced by ovariectomy on the acute effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in a model of rat poor metabolizer of debrisoquine.
|
| 21 |
most probable transition path
(1 time)
|
Chemistry
(1 time)
|
NtrC (1 time)
|
2008 Finding transition pathways using the string method with swarms of trajectories.
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| 22 |
MPTP-induced
(1 time)
|
Cell Biology
(1 time)
|
DHA (2 times)
GDNF (1 time)
NTN (1 time)
|
2010 The effects of docosahexaenoic acid on glial derived neurotrophic factor and neurturin in bilateral rat model of Parkinson's disease.
|
| 23 |
MPTP-resistant
(1 time)
|
Neurology
(1 time)
|
---
|
2009 Strain-specific sensitivity to MPTP of C57BL/6 and BALB/c mice is age dependent.
|
| 24 |
mucin-producing tumor of the pancreas
(1 time)
|
General Surgery
(1 time)
|
CT (1 time)
ERCP (1 time)
|
2001 Mucin-producing tumor of the pancreas associated with pyothorax: report of a case.
|
| 25 |
multiprotein pore
(1 time)
|
Biochemistry
(1 time)
|
GK (1 time)
MPT (1 time)
|
2003 Diabetes induces metabolic adaptations in rat liver mitochondria: role of coenzyme Q and cardiolipin contents.
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| 26 |
murine protein tyrosine phosphatase
(1 time)
|
Psychopharmacology
(1 time)
|
---
|
2000 [The role of calcineurin on the induction of synaptic plasticity].
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| 27 |
myocardial pathology through permeability transition pore opening
(1 time)
|
Biochemistry
(1 time)
|
IFM (1 time)
SSM (1 time)
|
2016 Sex differences in the regulation of spatially distinct cardiac mitochondrial subpopulations.
|
| 28 |
N-methylating 4-phenyl-1,2,3,6-tetrahydropyridine to 1-methyl-4-phenyltetrahydropyridine
(1 time)
|
Biochemistry
(1 time)
|
---
|
1986 Role of N-methyltransferases in the neurotoxicity associated with the metabolites of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and other 4-substituted pyridines present in the environment.
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