1 |
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
(4135 times)
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Neurology (1744 times)
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PD (1650 times) DA (583 times) TH (452 times)
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1983 Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis.
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2 |
MPT pore
(6 times)
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Neurology (2 times)
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MPT (5 times) ANT (2 times) CsA (2 times)
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2009 Drugs targeting the mitochondrial pore act as cytotoxic and cytostatic agents in temozolomide-resistant glioma cells.
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3 |
mitochondrial permeability pore
(5 times)
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Metabolism (2 times)
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ALS (2 times) ER (1 time) GSK-3beta (1 time)
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2004 A unique pathway of cardiac myocyte death caused by hypoxia-acidosis.
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4 |
multiple tandem forward primers and a common reverse primer
(4 times)
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Hematology (2 times)
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G6PD (3 times) PCR (2 times) G871A (1 time)
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1999 Molecular basis of glucose-6-phosphate dehydrogenase deficiency among Filipinos.
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5 |
calcium-induced permeability transition pore
(2 times)
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Physiology (1 time)
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ATP (1 time) IS (1 time)
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2011 Mitochondrial KATP channels participate in the limitation of infarct size by cariporide.
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6 |
methyl-4-phenylpyridine
(2 times)
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Neurology (1 time)
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BG (1 time) HPLC (1 time) PD (1 time)
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1995 Neuronal changes in the substantia nigra with aging: a Golgi study.
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7 |
MPTP-injected
(2 times)
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Histocytochemistry (1 time)
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DHA (4 times) PD (2 times) SN (2 times)
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2016 The protective mechanism of docosahexaenoic acid in mouse model of Parkinson: The role of hemeoxygenase.
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8 |
1,2,3,6-tetrahydro-1-methyl-4-phenylpyridine
(1 time)
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Neurology (1 time)
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GC-MS (1 time)
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1999 Environmental MPTP as a factor in the aetiology of Parkinson's disease?
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9 |
1,2,3,6-tetrahydro-1-methyl-4-phenylpyridine hydrochloride
(1 time)
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Neurology (1 time)
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DA (1 time) mTOR (1 time) PD (1 time)
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2011 Nucleolar disruption in dopaminergic neurons leads to oxidative damage and parkinsonism through repression of mammalian target of rapamycin signaling.
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10 |
1-methyl-4-(2'-methylphenyl)-1,2,3,6-tetrahydrophine
(1 time)
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Medicine (1 time)
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FTD (1 time) PGRN (1 time)
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2012 Progranulin deficiency promotes neuroinflammation and neuron loss following toxin-induced injury.
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11 |
many dopaminergic cells of the SNc and retina from parkinsonian
(1 time)
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Parkinson Disease (1 time)
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SNc (1 time) TH (1 time)
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2013 Saffron pre-treatment offers neuroprotection to Nigral and retinal dopaminergic cells of MPTP-Treated mice.
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12 |
mean pulmonary trunk pressure
(1 time)
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Medicine (1 time)
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---
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2005 [Characterization of arrhythmia in pulmonary hypertension in patients with bronchial obstructive diseases].
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13 |
membrane potential and mitochondrial transition pore opening
(1 time)
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Biochemistry (1 time)
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eNOS and iNOS (1 time) hCG (1 time) HUVEC (1 time)
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2015 Human Chorionic Gonadotropin Protects Vascular Endothelial Cells from Oxidative Stress by Apoptosis Inhibition, Cell Survival Signalling Activation and Mitochondrial Function Protection.
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14 |
metabolic profiling in the SN and STR of 1-methyl-1,2,3,6-tetrahydropyridine
(1 time)
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Diagnostic Imaging (1 time)
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PD (1 time) SN (1 time) STR (1 time)
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2016 Neurometabolic profiles of the substantia nigra and striatum of MPTP-intoxicated common marmosets: An in vivo proton MRS study at 9.4T.
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15 |
mitochondrial calcium retention capacity, indicating decreased permeability transition pore
(1 time)
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Drug Therapy (1 time)
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---
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2019 Mitochondrial Complex I Inhibition by Metformin Limits Reperfusion Injury.
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16 |
mitochondrial susceptibility to calcium-induced permeability transition pore
(1 time)
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Toxicology (1 time)
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MDA (1 time) SH (1 time) SOD (1 time)
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2012 In vitro salicylate does not further impair aging-induced brain mitochondrial dysfunction.
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17 |
models were established via treatment with rotenone or 1methyl4phenyl1,2,3,6-tetrahydropyridine
(1 time)
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Molecular Biology (1 time)
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DA (1 time) GFAP (1 time) NeuN (1 time)
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2022 Comparison of the effect of rotenone and 1‑methyl‑4‑phenyl‑1,2,3,6‑tetrahydropyridine on inducing chronic Parkinson's disease in mouse models.
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18 |
modulation of sensitivity ofmitochondnal permeability transition pore
(1 time)
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Physiology (1 time)
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NO (1 time) NOS (1 time)
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2009 [No-dependent modulation of the sensitivity of the mitochondrial permeability transition pore opening under ischemia-reperfusion of the isolated heart].
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19 |
monkey unilaterally lesioned with 4-phenyl-1,2,3,6-tetrahydropyridine hydrochloride
(1 time)
|
Diagnostic Imaging (1 time)
|
---
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1996 Mapping drug-induced changes in cerebral R2* by Multiple Gradient Recalled Echo functional MRI.
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20 |
more susceptible to neurotoxic effects of 1,2,3,6-tetrahydropyridine
(1 time)
|
Neurology (1 time)
|
DA (1 time)
|
1996 Changes induced by ovariectomy on the acute effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in a model of rat poor metabolizer of debrisoquine.
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21 |
most probable transition path
(1 time)
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Chemistry (1 time)
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NtrC (1 time)
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2008 Finding transition pathways using the string method with swarms of trajectories.
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22 |
MPTP-induced
(1 time)
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Cell Biology (1 time)
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DHA (2 times) GDNF (1 time) NTN (1 time)
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2010 The effects of docosahexaenoic acid on glial derived neurotrophic factor and neurturin in bilateral rat model of Parkinson's disease.
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23 |
MPTP-resistant
(1 time)
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Neurology (1 time)
|
---
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2009 Strain-specific sensitivity to MPTP of C57BL/6 and BALB/c mice is age dependent.
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24 |
mucin-producing tumor of the pancreas
(1 time)
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General Surgery (1 time)
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CT (1 time) ERCP (1 time)
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2001 Mucin-producing tumor of the pancreas associated with pyothorax: report of a case.
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25 |
multi-rate Poisson tree process
(1 time)
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Parasitology (1 time)
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ESUs (1 time) PTP (1 time)
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2020 Molecular diversity and coalescent species delimitation of avian haemosporidian parasites in an endemic bird species of South America.
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26 |
multiprotein pore
(1 time)
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Biochemistry (1 time)
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GK (1 time) MPT (1 time)
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2003 Diabetes induces metabolic adaptations in rat liver mitochondria: role of coenzyme Q and cardiolipin contents.
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27 |
murine protein tyrosine phosphatase
(1 time)
|
Psychopharmacology (1 time)
|
---
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2001 [The role of calcineurin on the induction of synaptic plasticity].
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28 |
myocardial pathology through permeability transition pore opening
(1 time)
|
Biochemistry (1 time)
|
IFM (1 time) SSM (1 time)
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2016 Sex differences in the regulation of spatially distinct cardiac mitochondrial subpopulations.
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29 |
N-methylating 4-phenyl-1,2,3,6-tetrahydropyridine to 1-methyl-4-phenyltetrahydropyridine
(1 time)
|
Biochemistry (1 time)
|
---
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1986 Role of N-methyltransferases in the neurotoxicity associated with the metabolites of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and other 4-substituted pyridines present in the environment.
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