| 1 |
nuclear factor-kappaB
(25591 times)
|
Biochemistry
(3248 times)
|
TNF-alpha (4379 times)
LPS (3233 times)
iNOS (1915 times)
|
1988 Transcription and replication of human immunodeficiency virus-1 in B lymphocytes in vitro.
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| 2 |
nuclear factor kappa-light-chain-enhancer of activated B cells
(1245 times)
|
Pharmacology
(128 times)
|
TNF-alpha (189 times)
LPS (144 times)
IL (118 times)
|
2006 Expression of inflammation-related genes in endothelial cells is not directly affected by microparticles from preeclamptic patients.
|
| 3 |
nuclear transcription factor-kappaB
(541 times)
|
Pharmacology
(87 times)
|
TNF-alpha (114 times)
LPS (88 times)
NO (52 times)
|
1997 Tumor necrosis factor alpha activates NF-kappaB in acid sphingomyelinase-deficient mouse embryonic fibroblasts.
|
| 4 |
nuclear factor-kappa-gene binding
(29 times)
|
Pharmacology
(7 times)
|
IL-6 (5 times)
SOD (5 times)
MAPK (4 times)
|
2003 [Inhibition of activation of nuclear factor-kappaB enhanced apoptosis of leukemic cells induced by homoharringtonine].
|
| 5 |
nuclear factor kappa B protein
(19 times)
|
Pharmacology
(4 times)
|
TNF-alpha (5 times)
COX-2 (2 times)
iNOS (2 times)
|
2006 Tripterine inhibits the expression of adhesion molecules in activated endothelial cells.
|
| 6 |
transcription factor kappaB
(19 times)
|
Biochemistry
(4 times)
|
AP (2 times)
CIA (2 times)
ELISA (2 times)
|
1997 Interferon-gamma-induced interferon regulatory factor-1 (IRF-1) expression in rodent and human islet cells precedes nitric oxide production.
|
| 7 |
nuclear factor of kappa light polypeptide gene enhancer in B-cells
(17 times)
|
Medicine
(3 times)
|
AP-1 (2 times)
CagA (2 times)
IkappaB (2 times)
|
2006 Corticotropin releasing hormone and the skin.
|
| 8 |
necrosis factor-kappaB
(8 times)
|
Rheumatology
(1 time)
|
ROS (3 times)
APR (2 times)
TNF-alpha (2 times)
|
2000 Cyclosporin A protects against angiotensin II-induced end-organ damage in double transgenic rats harboring human renin and angiotensinogen genes.
|
| 9 |
nuclear kappa B factor
(7 times)
|
Biochemistry
(4 times)
|
IL-1beta (5 times)
IL-6 (5 times)
TNF-alpha (5 times)
|
2011 Molecular mechanisms of inflammation during exacerbations of chronic obstructive pulmonary disease.
|
| 10 |
nuclear factor kappa activated B cells
(6 times)
|
Neoplasms
(3 times)
|
LPO (3 times)
BL (2 times)
PARP-1 (2 times)
|
2013 A selective antagonist reveals a potential role of G protein-coupled receptor 55 in platelet and endothelial cell function.
|
| 11 |
nuclear factor kappa enhancer binding protein
(5 times)
|
Natural Science Disciplines
(1 time)
|
TNF-alpha (2 times)
COX-2 (1 time)
ECs (1 time)
|
2009 The role of ubiquitin in NF-kappaB regulatory pathways.
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| 12 |
nuclear factor of the kappa-enhancer in B cells
(4 times)
|
Pharmacology
(2 times)
|
IL (2 times)
C/EBP (1 time)
CNS (1 time)
|
2004 Caspase-1 activates nuclear factor of the kappa-enhancer in B cells independently of its enzymatic activity.
|
| 13 |
nuclear regulatory factor-kappaB
(4 times)
|
Allergy and Immunology
(2 times)
|
TNF-alpha (3 times)
IL (2 times)
LPS (2 times)
|
1999 A reactive oxygen-generating system activates nuclear factor-kappaB and releases tumor necrosis factor-alpha in coronary smooth muscle cells.
|
| 14 |
(IkappaB-alpha)-nuclear factor kappaB
(3 times)
|
Inflammation
(1 time)
|
IkappaBalpha (3 times)
iNOS (3 times)
LPS (3 times)
|
2015 Methylene Blue Attenuates iNOS Induction Through Suppression of Transcriptional Factor Binding Amid iNOS mRNA Transcription.
|
| 15 |
nuclear factor for immunoglobulin kappa chain in B cells
(3 times)
|
Cell Biology
(1 time)
|
PMA (2 times)
AP-1 (1 time)
CBN (1 time)
|
2001 Modulation of CREB and NF-kappaB signal transduction by cannabinol in activated thymocytes.
|
| 16 |
NF kappa-light-chain-enhancer of activated B cells
(2 times)
|
Allergy and Immunology
(2 times)
|
6-MP (1 time)
6-T-GTP (1 time)
CXCL8 (1 time)
|
2014 Inhibition of GTPase Rac1 in endothelium by 6-mercaptopurine results in immunosuppression in nonimmune cells: new target for an old drug.
|
| 17 |
nuclear factor binding kappaB site
(2 times)
|
Biochemistry
(1 time)
|
PKC (1 time)
|
1996 Up-regulation of protein kinase C-epsilon promotes the expression of cytokine-inducible nitric oxide synthase in RAW 264.7 cells.
|
| 18 |
nuclear factor-kappaB activation
(2 times)
|
Pathology
(1 time)
|
AA (1 time)
COX-2 (1 time)
EC (1 time)
|
2001 Sequence analysis identifies TTRAP, a protein that associates with CD40 and TNF receptor-associated factors, as a member of a superfamily of divalent cation-dependent phosphodiesterases.
|
| 19 |
nuclear translocation of the transcription factor kappa-B
(2 times)
|
General Surgery
(1 time)
|
EMSA (1 time)
LPS (1 time)
NAC (1 time)
|
2003 Reactive oxygen species mediate endotoxin-induced human dermal endothelial NF-kappaB activation.
|
| 20 |
(IkappaB)-nuclear factor-kappa B
(1 time)
|
Cell Biology
(1 time)
|
IFN-gamma (1 time)
IkappaB (1 time)
JAKs (1 time)
|
2010 Reactive oxygen species are involved in the IFN-gamma-stimulated production of Th2 chemokines in HaCaT keratinocytes.
|
| 21 |
beta-IkappaBalpha-nuclear factor-kappaB
(1 time)
|
Chemistry
(1 time)
|
AP-1 (1 time)
CIA (1 time)
Col II (1 time)
|
2018 Chondroprotective Effects and Mechanisms of Dextromethorphan: Repurposing Antitussive Medication for Osteoarthritis Treatment.
|
| 22 |
factor nuclear receptor kappa B
(1 time)
|
Allergy and Immunology
(1 time)
|
PBC (1 time)
PPARalpha (1 time)
PSC (1 time)
|
2022 Fenofibrate Downregulates NF-κB Signaling to Inhibit Pro-inflammatory Cytokine Secretion in Human THP-1 Macrophages and During Primary Biliary Cholangitis.
|
| 23 |
GPER-ERK-nuclear factor kappa B
(1 time)
|
Molecular Biology
(1 time)
|
CI/RI (1 time)
ELISAs (1 time)
ERK (1 time)
|
2022 Icaritin inhibits neuroinflammation in a rat cerebral ischemia model by regulating microglial polarization through the GPER-ERK-NF-κB signaling pathway.
|
| 24 |
IgE-FcepsilonRI-nuclear factor kappa B
(1 time)
|
Clinical Medicine
(1 time)
|
AR (1 time)
IgE (1 time)
IL (1 time)
|
2021 Investigating the inflammatory cascade effect of basophil activation in children with allergic rhinitis or asthma, via the IgE-FcepsilonRI-NF-kappaB signaling pathway.
|
| 25 |
IKK-IkappaB-nuclear factor kappaB
(1 time)
|
Pharmacology
(1 time)
|
DSB (1 time)
IKK (1 time)
LPS (1 time)
|
2014 Deoxysappanone B, a homoisoflavone from the Chinese medicinal plant Caesalpinia sappan L., protects neurons from microglia-mediated inflammatory injuries via inhibition of IkappaB kinase (IKK)-NF-kappaB and p38/ERK MAPK pathways.
|
| 26 |
n factor-kappaB
(1 time)
|
Pulmonary Medicine
(1 time)
|
AA (1 time)
HI (1 time)
IL (1 time)
|
2015 p-STAT6, PU.1, and NF-kappaB are involved in allergen-induced late-phase airway inflammation in asthma patients.
|
| 27 |
neuronal factor kappaB
(1 time)
|
Neoplasms
(1 time)
|
CTLs (1 time)
FasL (1 time)
NK (1 time)
|
2004 The role of Fas ligand and transforming growth factor beta in tumor progression: molecular mechanisms of immune privilege via Fas-mediated apoptosis and potential targets for cancer therapy.
|
| 28 |
neurotrophic factor kappaB
(1 time)
|
Chemistry
(1 time)
|
MGO (2 times)
AGEs (1 time)
HBMEC (1 time)
|
2015 The protective role of isorhamnetin on human brain microvascular endothelial cells from cytotoxicity induced by methylglyoxal and oxygen-glucose deprivation.
|
| 29 |
NF -kappa B
(1 time)
|
Biology
(1 time)
|
NIK (1 time)
Smac (1 time)
TNF-alpha (1 time)
|
2016 The SMAC mimetic BV6 induces cell death and sensitizes different cell lines to TNF-alpha and TRAIL-induced apoptosis.
|
| 30 |
NF(kappa)-B
(1 time)
|
Neurology
(1 time)
|
COX-1 (1 time)
COX-2 (1 time)
HF (1 time)
|
2005 High dietary fat induces NADPH oxidase-associated oxidative stress and inflammation in rat cerebral cortex.
|
| 31 |
NF-kappa B inhibitor alpha
(1 time)
|
Complementary Therapies
(1 time)
|
BALF (1 time)
hvKp (1 time)
|
2021 Influence of LncRNA NKILA on Bloodstream Infection of Hypervirulent Klebsiella pneumoniae and Its Ability to Induce Delayed Neutrophil Apoptosis.
|
| 32 |
NF-kappa-beta
(1 time)
|
Medicine
(1 time)
|
PAH (1 time)
WES (1 time)
|
2021 Novel TNIP2 and TRAF2 Variants Are Implicated in the Pathogenesis of Pulmonary Arterial Hypertension.
|
| 33 |
NF-kappaappaB
(1 time)
|
Reproductive Medicine
(1 time)
|
ABP (1 time)
AR (1 time)
ATZ (1 time)
|
2012 The protective effects of quercetin on the cytotoxicity of atrazine on rat Sertoli-germ cell co-culture.
|
| 34 |
NGF-dependent nuclear transcription factor-kappaB
(1 time)
|
Neurology
(1 time)
|
CARD (1 time)
NGF (1 time)
|
2001 A prosurvival function for the p75 receptor death domain mediated via the caspase recruitment domain receptor-interacting protein 2.
|
| 35 |
non-canonical-nuclear factor kappaB
(1 time)
|
Cells
(1 time)
|
LT (1 time)
|
2021 LTbetaR Signaling Controls Lymphatic Migration of Immune Cells.
|
| 36 |
Notch1-Nuclear factor-kappaB
(1 time)
|
Substance-Related Disorders
(1 time)
|
ASH (1 time)
|
2013 Notch1-nuclear factor kappaB involves in oxidative stress-induced alcoholic steatohepatitis.
|
| 37 |
nuclear factor kappa-B transcription factor
(1 time)
|
Complementary Therapies
(1 time)
|
AMPK (1 time)
PPARgamma (1 time)
ROS (1 time)
|
2015 Lemon verbena (Lippia citriodora) polyphenols alleviate obesity-related disturbances in hypertrophic adipocytes through AMPK-dependent mechanisms.
|
| 38 |
nuclear factor kappa-light polypeptide B
(1 time)
|
Cell Biology
(1 time)
|
PKC (1 time)
|
2017 Combining Fluorescence and Bioluminescence Microscopy to Study the Series of Events from Cellular Signal Transduction to Gene Expression.
|
| 39 |
nuclear factor kappa-light-chain-enhancer of activated genetic polymorphisms in B cells
(1 time)
|
Communicable Diseases
(1 time)
|
---
|
2018 [Association between nuclear factor kappa-light-chain-enhancer of activated B cells genetic polymorphisms and HCV susceptibility among the Chinese population under high-risk].
|
| 40 |
Nuclear Factor kappaappa beta
(1 time)
|
Neoplasms
(1 time)
|
IkappaBalpha (1 time)
|
2011 NF-kappaB activation by peroxynitrite through IkappaBalpha-dependent phosphorylation versus nitration in colon cancer cells.
|
| 41 |
nuclear factor-kappa binding protein
(1 time)
|
Biochemistry
(1 time)
|
AR (1 time)
ICAM (1 time)
TNF-alpha (1 time)
|
2003 Role of aldose reductase in TNF-alpha-induced apoptosis of vascular endothelial cells.
|
| 42 |
nuclear factor-kappaB inhibitor
(1 time)
|
Reproductive Medicine
(1 time)
|
CIS (1 time)
GSH-Px (1 time)
i.p (1 time)
|
2009 Chemoprotective effect of a nuclear factor-kappaB inhibitor, pyrrolidine dithiocarbamate, against cisplatin-induced testicular damage in rats.
|
| 43 |
nuclear factor-kappaB reporter
(1 time)
|
Microbiology
(1 time)
|
---
|
2019 Functional Multigenomic Screening of Human-Associated Bacteria for NF-kappaB-Inducing Bioactive Effectors.
|
| 44 |
Nuclear Factors at kappa-chain promoters in B-cells
(1 time)
|
Allergy and Immunology
(1 time)
|
I-kappaB (1 time)
TNFR1 (1 time)
|
2008 Ubiquitin-mediated regulation of TNFR1 signaling.
|
| 45 |
nuclear factors kappaB, an enhancer
(1 time)
|
Veterinary Medicine
(1 time)
|
CrHis (1 time)
FBW (1 time)
FI (1 time)
|
2013 Chromium histidinate protects against heat stress by modulating the expression of hepatic nuclear transcription factors in quail.
|
| 46 |
nuclear phosphorylated factor-kappaB
(1 time)
|
Biology
(1 time)
|
HUVECs (1 time)
IR (1 time)
NSCLC (1 time)
|
2019 Involvement of endothelial CK2 in the radiation induced perivascular resistant niche (PVRN) and the induction of radioresistance for non-small cell lung cancer (NSCLC) cells.
|
| 47 |
nuclear transcription factor-kappa B expression
(1 time)
|
Complementary Therapies
(1 time)
|
ROS (1 time)
STZ (1 time)
|
2009 [Effect of Astragalus and Arctium in different combinations on reactive oxygen species content and nuclear transcription factor kappaB expression in renal tissue of streptozotocin rats].
|
| 48 |
nuclear transfactor-Kappab
(1 time)
|
Chemistry
(1 time)
|
EGCG (1 time)
PEDF (1 time)
VEGF (1 time)
|
2018 Epigallocatechin gallate inhibits corneal neovascularization in ratalkaline burn model.
|
| 49 |
nuclear translocation and activation of factor-kappa B
(1 time)
|
Cell Biology
(1 time)
|
ALF (1 time)
Nrf2 (1 time)
OI (1 time)
|
2021 Protective Role of 4-Octyl Itaconate in Murine LPS/D-GalN-Induced Acute Liver Failure via Inhibiting Inflammation, Oxidative Stress, and Apoptosis.
|
| 50 |
reducednuclear factor kappa B
(1 time)
|
Biochemistry
(1 time)
|
ATF4 (1 time)
HRCEpiC (1 time)
HRPTEpic (1 time)
|
2020 Metformin rescues Parkin protein expression and mitophagy in high glucose-challenged human renal epithelial cells by inhibiting NF-kappaB via PP2A activation.
|
| 51 |
STAT6-ERK-nuclear factor kappa beta
(1 time)
|
Hematology
(1 time)
|
ALL (1 time)
ERK (1 time)
IGF1 (1 time)
|
2018 Synergistic action of dual IGF1/R and MEK inhibition sensitizes childhood acute lymphoblastic leukemia (ALL) cells to cytotoxic agents and involves downregulation of STAT6 and PDAP1.
|
| 52 |
TNF-alpha-induced-nuclear factor-kappa B
(1 time)
|
Neoplasms
(1 time)
|
---
|
2007 Aqueous extract of Magnolia officinalis mediates proliferative capacity, p21WAF1 expression and TNF-alpha-induced NF-kappaB activity in human urinary bladder cancer 5637 cells; involvement of p38 MAP kinase.
|
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