1 |
nuclear factor-kappaB
(25591 times)
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Biochemistry (3248 times)
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TNF-alpha (4379 times) LPS (3233 times) iNOS (1915 times)
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1988 Transcription and replication of human immunodeficiency virus-1 in B lymphocytes in vitro.
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2 |
nuclear factor kappa-light-chain-enhancer of activated B cells
(1245 times)
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Pharmacology (128 times)
|
TNF-alpha (189 times) LPS (144 times) IL (118 times)
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2006 Expression of inflammation-related genes in endothelial cells is not directly affected by microparticles from preeclamptic patients.
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3 |
nuclear transcription factor-kappaB
(541 times)
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Pharmacology (87 times)
|
TNF-alpha (114 times) LPS (88 times) NO (52 times)
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1997 Tumor necrosis factor alpha activates NF-kappaB in acid sphingomyelinase-deficient mouse embryonic fibroblasts.
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4 |
nuclear factor-kappa-gene binding
(29 times)
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Pharmacology (7 times)
|
IL-6 (5 times) SOD (5 times) MAPK (4 times)
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2003 [Inhibition of activation of nuclear factor-kappaB enhanced apoptosis of leukemic cells induced by homoharringtonine].
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5 |
nuclear factor kappa B protein
(19 times)
|
Pharmacology (4 times)
|
TNF-alpha (5 times) COX-2 (2 times) iNOS (2 times)
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2006 Tripterine inhibits the expression of adhesion molecules in activated endothelial cells.
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6 |
transcription factor kappaB
(19 times)
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Biochemistry (4 times)
|
AP (2 times) CIA (2 times) ELISA (2 times)
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1997 Interferon-gamma-induced interferon regulatory factor-1 (IRF-1) expression in rodent and human islet cells precedes nitric oxide production.
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7 |
nuclear factor of kappa light polypeptide gene enhancer in B-cells
(17 times)
|
Medicine (3 times)
|
AP-1 (2 times) CagA (2 times) IkappaB (2 times)
|
2006 Corticotropin releasing hormone and the skin.
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8 |
necrosis factor-kappaB
(8 times)
|
Rheumatology (1 time)
|
ROS (3 times) APR (2 times) TNF-alpha (2 times)
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2000 Cyclosporin A protects against angiotensin II-induced end-organ damage in double transgenic rats harboring human renin and angiotensinogen genes.
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9 |
nuclear kappa B factor
(7 times)
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Biochemistry (4 times)
|
IL-1beta (5 times) IL-6 (5 times) TNF-alpha (5 times)
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2011 Molecular mechanisms of inflammation during exacerbations of chronic obstructive pulmonary disease.
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10 |
nuclear factor kappa activated B cells
(6 times)
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Neoplasms (3 times)
|
LPO (3 times) BL (2 times) PARP-1 (2 times)
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2013 A selective antagonist reveals a potential role of G protein-coupled receptor 55 in platelet and endothelial cell function.
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11 |
nuclear factor kappa enhancer binding protein
(5 times)
|
Natural Science Disciplines (1 time)
|
TNF-alpha (2 times) COX-2 (1 time) ECs (1 time)
|
2009 The role of ubiquitin in NF-kappaB regulatory pathways.
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12 |
nuclear factor of the kappa-enhancer in B cells
(4 times)
|
Pharmacology (2 times)
|
IL (2 times) C/EBP (1 time) CNS (1 time)
|
2004 Caspase-1 activates nuclear factor of the kappa-enhancer in B cells independently of its enzymatic activity.
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13 |
nuclear regulatory factor-kappaB
(4 times)
|
Allergy and Immunology (2 times)
|
TNF-alpha (3 times) IL (2 times) LPS (2 times)
|
1999 A reactive oxygen-generating system activates nuclear factor-kappaB and releases tumor necrosis factor-alpha in coronary smooth muscle cells.
|
14 |
(IkappaB-alpha)-nuclear factor kappaB
(3 times)
|
Inflammation (1 time)
|
IkappaBalpha (3 times) iNOS (3 times) LPS (3 times)
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2015 Methylene Blue Attenuates iNOS Induction Through Suppression of Transcriptional Factor Binding Amid iNOS mRNA Transcription.
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15 |
nuclear factor for immunoglobulin kappa chain in B cells
(3 times)
|
Cell Biology (1 time)
|
PMA (2 times) AP-1 (1 time) CBN (1 time)
|
2001 Modulation of CREB and NF-kappaB signal transduction by cannabinol in activated thymocytes.
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16 |
NF kappa-light-chain-enhancer of activated B cells
(2 times)
|
Allergy and Immunology (2 times)
|
6-MP (1 time) 6-T-GTP (1 time) CXCL8 (1 time)
|
2014 Inhibition of GTPase Rac1 in endothelium by 6-mercaptopurine results in immunosuppression in nonimmune cells: new target for an old drug.
|
17 |
nuclear factor binding kappaB site
(2 times)
|
Biochemistry (1 time)
|
PKC (1 time)
|
1996 Up-regulation of protein kinase C-epsilon promotes the expression of cytokine-inducible nitric oxide synthase in RAW 264.7 cells.
|
18 |
nuclear factor-kappaB activation
(2 times)
|
Pathology (1 time)
|
AA (1 time) COX-2 (1 time) EC (1 time)
|
2001 Sequence analysis identifies TTRAP, a protein that associates with CD40 and TNF receptor-associated factors, as a member of a superfamily of divalent cation-dependent phosphodiesterases.
|
19 |
nuclear translocation of the transcription factor kappa-B
(2 times)
|
General Surgery (1 time)
|
EMSA (1 time) LPS (1 time) NAC (1 time)
|
2003 Reactive oxygen species mediate endotoxin-induced human dermal endothelial NF-kappaB activation.
|
20 |
(IkappaB)-nuclear factor-kappa B
(1 time)
|
Cell Biology (1 time)
|
IFN-gamma (1 time) IkappaB (1 time) JAKs (1 time)
|
2010 Reactive oxygen species are involved in the IFN-gamma-stimulated production of Th2 chemokines in HaCaT keratinocytes.
|
21 |
beta-IkappaBalpha-nuclear factor-kappaB
(1 time)
|
Chemistry (1 time)
|
AP-1 (1 time) CIA (1 time) Col II (1 time)
|
2018 Chondroprotective Effects and Mechanisms of Dextromethorphan: Repurposing Antitussive Medication for Osteoarthritis Treatment.
|
22 |
factor nuclear receptor kappa B
(1 time)
|
Allergy and Immunology (1 time)
|
PBC (1 time) PPARalpha (1 time) PSC (1 time)
|
2022 Fenofibrate Downregulates NF-κB Signaling to Inhibit Pro-inflammatory Cytokine Secretion in Human THP-1 Macrophages and During Primary Biliary Cholangitis.
|
23 |
GPER-ERK-nuclear factor kappa B
(1 time)
|
Molecular Biology (1 time)
|
CI/RI (1 time) ELISAs (1 time) ERK (1 time)
|
2022 Icaritin inhibits neuroinflammation in a rat cerebral ischemia model by regulating microglial polarization through the GPER-ERK-NF-κB signaling pathway.
|
24 |
IgE-FcepsilonRI-nuclear factor kappa B
(1 time)
|
Clinical Medicine (1 time)
|
AR (1 time) IgE (1 time) IL (1 time)
|
2021 Investigating the inflammatory cascade effect of basophil activation in children with allergic rhinitis or asthma, via the IgE-FcepsilonRI-NF-kappaB signaling pathway.
|
25 |
IKK-IkappaB-nuclear factor kappaB
(1 time)
|
Pharmacology (1 time)
|
DSB (1 time) IKK (1 time) LPS (1 time)
|
2014 Deoxysappanone B, a homoisoflavone from the Chinese medicinal plant Caesalpinia sappan L., protects neurons from microglia-mediated inflammatory injuries via inhibition of IkappaB kinase (IKK)-NF-kappaB and p38/ERK MAPK pathways.
|
26 |
n factor-kappaB
(1 time)
|
Pulmonary Medicine (1 time)
|
AA (1 time) HI (1 time) IL (1 time)
|
2015 p-STAT6, PU.1, and NF-kappaB are involved in allergen-induced late-phase airway inflammation in asthma patients.
|
27 |
neuronal factor kappaB
(1 time)
|
Neoplasms (1 time)
|
CTLs (1 time) FasL (1 time) NK (1 time)
|
2004 The role of Fas ligand and transforming growth factor beta in tumor progression: molecular mechanisms of immune privilege via Fas-mediated apoptosis and potential targets for cancer therapy.
|
28 |
neurotrophic factor kappaB
(1 time)
|
Chemistry (1 time)
|
MGO (2 times) AGEs (1 time) HBMEC (1 time)
|
2015 The protective role of isorhamnetin on human brain microvascular endothelial cells from cytotoxicity induced by methylglyoxal and oxygen-glucose deprivation.
|
29 |
NF -kappa B
(1 time)
|
Biology (1 time)
|
NIK (1 time) Smac (1 time) TNF-alpha (1 time)
|
2016 The SMAC mimetic BV6 induces cell death and sensitizes different cell lines to TNF-alpha and TRAIL-induced apoptosis.
|
30 |
NF(kappa)-B
(1 time)
|
Neurology (1 time)
|
COX-1 (1 time) COX-2 (1 time) HF (1 time)
|
2005 High dietary fat induces NADPH oxidase-associated oxidative stress and inflammation in rat cerebral cortex.
|
31 |
NF-kappa B inhibitor alpha
(1 time)
|
Complementary Therapies (1 time)
|
BALF (1 time) hvKp (1 time)
|
2021 Influence of LncRNA NKILA on Bloodstream Infection of Hypervirulent Klebsiella pneumoniae and Its Ability to Induce Delayed Neutrophil Apoptosis.
|
32 |
NF-kappa-beta
(1 time)
|
Medicine (1 time)
|
PAH (1 time) WES (1 time)
|
2021 Novel TNIP2 and TRAF2 Variants Are Implicated in the Pathogenesis of Pulmonary Arterial Hypertension.
|
33 |
NF-kappaappaB
(1 time)
|
Reproductive Medicine (1 time)
|
ABP (1 time) AR (1 time) ATZ (1 time)
|
2012 The protective effects of quercetin on the cytotoxicity of atrazine on rat Sertoli-germ cell co-culture.
|
34 |
NGF-dependent nuclear transcription factor-kappaB
(1 time)
|
Neurology (1 time)
|
CARD (1 time) NGF (1 time)
|
2001 A prosurvival function for the p75 receptor death domain mediated via the caspase recruitment domain receptor-interacting protein 2.
|
35 |
non-canonical-nuclear factor kappaB
(1 time)
|
Cells (1 time)
|
LT (1 time)
|
2021 LTbetaR Signaling Controls Lymphatic Migration of Immune Cells.
|
36 |
Notch1-Nuclear factor-kappaB
(1 time)
|
Substance-Related Disorders (1 time)
|
ASH (1 time)
|
2013 Notch1-nuclear factor kappaB involves in oxidative stress-induced alcoholic steatohepatitis.
|
37 |
nuclear factor kappa-B transcription factor
(1 time)
|
Complementary Therapies (1 time)
|
AMPK (1 time) PPARgamma (1 time) ROS (1 time)
|
2015 Lemon verbena (Lippia citriodora) polyphenols alleviate obesity-related disturbances in hypertrophic adipocytes through AMPK-dependent mechanisms.
|
38 |
nuclear factor kappa-light polypeptide B
(1 time)
|
Cell Biology (1 time)
|
PKC (1 time)
|
2017 Combining Fluorescence and Bioluminescence Microscopy to Study the Series of Events from Cellular Signal Transduction to Gene Expression.
|
39 |
nuclear factor kappa-light-chain-enhancer of activated genetic polymorphisms in B cells
(1 time)
|
Communicable Diseases (1 time)
|
---
|
2018 [Association between nuclear factor kappa-light-chain-enhancer of activated B cells genetic polymorphisms and HCV susceptibility among the Chinese population under high-risk].
|
40 |
Nuclear Factor kappaappa beta
(1 time)
|
Neoplasms (1 time)
|
IkappaBalpha (1 time)
|
2011 NF-kappaB activation by peroxynitrite through IkappaBalpha-dependent phosphorylation versus nitration in colon cancer cells.
|
41 |
nuclear factor-kappa binding protein
(1 time)
|
Biochemistry (1 time)
|
AR (1 time) ICAM (1 time) TNF-alpha (1 time)
|
2003 Role of aldose reductase in TNF-alpha-induced apoptosis of vascular endothelial cells.
|
42 |
nuclear factor-kappaB inhibitor
(1 time)
|
Reproductive Medicine (1 time)
|
CIS (1 time) GSH-Px (1 time) i.p (1 time)
|
2009 Chemoprotective effect of a nuclear factor-kappaB inhibitor, pyrrolidine dithiocarbamate, against cisplatin-induced testicular damage in rats.
|
43 |
nuclear factor-kappaB reporter
(1 time)
|
Microbiology (1 time)
|
---
|
2019 Functional Multigenomic Screening of Human-Associated Bacteria for NF-kappaB-Inducing Bioactive Effectors.
|
44 |
Nuclear Factors at kappa-chain promoters in B-cells
(1 time)
|
Allergy and Immunology (1 time)
|
I-kappaB (1 time) TNFR1 (1 time)
|
2008 Ubiquitin-mediated regulation of TNFR1 signaling.
|
45 |
nuclear factors kappaB, an enhancer
(1 time)
|
Veterinary Medicine (1 time)
|
CrHis (1 time) FBW (1 time) FI (1 time)
|
2013 Chromium histidinate protects against heat stress by modulating the expression of hepatic nuclear transcription factors in quail.
|
46 |
nuclear phosphorylated factor-kappaB
(1 time)
|
Biology (1 time)
|
HUVECs (1 time) IR (1 time) NSCLC (1 time)
|
2019 Involvement of endothelial CK2 in the radiation induced perivascular resistant niche (PVRN) and the induction of radioresistance for non-small cell lung cancer (NSCLC) cells.
|
47 |
nuclear transcription factor-kappa B expression
(1 time)
|
Complementary Therapies (1 time)
|
ROS (1 time) STZ (1 time)
|
2009 [Effect of Astragalus and Arctium in different combinations on reactive oxygen species content and nuclear transcription factor kappaB expression in renal tissue of streptozotocin rats].
|
48 |
nuclear transfactor-Kappab
(1 time)
|
Chemistry (1 time)
|
EGCG (1 time) PEDF (1 time) VEGF (1 time)
|
2018 Epigallocatechin gallate inhibits corneal neovascularization in ratalkaline burn model.
|
49 |
nuclear translocation and activation of factor-kappa B
(1 time)
|
Cell Biology (1 time)
|
ALF (1 time) Nrf2 (1 time) OI (1 time)
|
2021 Protective Role of 4-Octyl Itaconate in Murine LPS/D-GalN-Induced Acute Liver Failure via Inhibiting Inflammation, Oxidative Stress, and Apoptosis.
|
50 |
reducednuclear factor kappa B
(1 time)
|
Biochemistry (1 time)
|
ATF4 (1 time) HRCEpiC (1 time) HRPTEpic (1 time)
|
2020 Metformin rescues Parkin protein expression and mitophagy in high glucose-challenged human renal epithelial cells by inhibiting NF-kappaB via PP2A activation.
|
51 |
STAT6-ERK-nuclear factor kappa beta
(1 time)
|
Hematology (1 time)
|
ALL (1 time) ERK (1 time) IGF1 (1 time)
|
2018 Synergistic action of dual IGF1/R and MEK inhibition sensitizes childhood acute lymphoblastic leukemia (ALL) cells to cytotoxic agents and involves downregulation of STAT6 and PDAP1.
|
52 |
TNF-alpha-induced-nuclear factor-kappa B
(1 time)
|
Neoplasms (1 time)
|
---
|
2007 Aqueous extract of Magnolia officinalis mediates proliferative capacity, p21WAF1 expression and TNF-alpha-induced NF-kappaB activity in human urinary bladder cancer 5637 cells; involvement of p38 MAP kinase.
|