| 1 |
protein kinase RNA-like endoplasmic reticulum kinase
(399 times)
|
Biochemistry
(53 times)
|
ER (196 times)
UPR (96 times)
CHOP (88 times)
|
2001 Characterization of phosphopeptides from protein digests using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and nanoelectrospray quadrupole time-of-flight mass spectrometry.
|
| 2 |
protein kinase RNA-like ER kinase
(266 times)
|
Cell Biology
(35 times)
|
ER (209 times)
UPR (84 times)
CHOP (72 times)
|
2002 Distinct roles of activating transcription factor 6 (ATF6) and double-stranded RNA-activated protein kinase-like endoplasmic reticulum kinase (PERK) in transcription during the mammalian unfolded protein response.
|
| 3 |
PKR-like ER kinase
(169 times)
|
Cell Biology
(30 times)
|
ER (117 times)
UPR (60 times)
CHOP (41 times)
|
2001 Translational control by the ER transmembrane kinase/ribonuclease IRE1 under ER stress.
|
| 4 |
Prospective Evaluation of Radial Keratotomy
(50 times)
|
Ophthalmology
(32 times)
|
RK (3 times)
BBR (2 times)
IOP (2 times)
|
1983 Rationale for and design of the National Eye Institute Prospective Evaluation of Radial Keratotomy (PERK) Study.
|
| 5 |
pancreatic ER kinase
(33 times)
|
Neurology
(7 times)
|
ER (24 times)
IRE1 (11 times)
UPR (8 times)
|
2002 Endoplasmic reticulum stress and the development of diabetes: a review.
|
| 6 |
pancreatic endoplasmic reticulum kinase
(20 times)
|
Pharmacology
(3 times)
|
ER (7 times)
UPR (7 times)
EAE (4 times)
|
2004 Cytoprotection by pre-emptive conditional phosphorylation of translation initiation factor 2.
|
| 7 |
protein kinase
(16 times)
|
General Surgery
(3 times)
|
ER (5 times)
ATF6 (3 times)
GRP78 (3 times)
|
2003 Cycloheximide inhibits neurotoxic responses induced by kainic acid in mice.
|
| 8 |
protein kinase RNA-activated-like ER kinase
(10 times)
|
Cell Biology
(3 times)
|
ER (10 times)
UPR (6 times)
CHOP (3 times)
|
2012 MicroRNA-30c-2* limits expression of proadaptive factor XBP1 in the unfolded protein response.
|
| 9 |
PKR-like ER protein kinase
(9 times)
|
Medicine
(2 times)
|
ER (9 times)
ATF6 (6 times)
IRE1 (6 times)
|
2007 [Unfolded protein response: its role in physiology and physiopathology].
|
| 10 |
PKR-like ER-resident kinase
(6 times)
|
Virology
(2 times)
|
ER (4 times)
ATF4 (3 times)
UPR (2 times)
|
2003 Protein synthesis and endoplasmic reticulum stress can be modulated by the hepatitis C virus envelope protein E2 through the eukaryotic initiation factor 2alpha kinase PERK.
|
| 11 |
proline-rich extensin-like receptor kinase
(6 times)
|
Botany
(3 times)
|
AGP (1 time)
BAECs (1 time)
BFA (1 time)
|
2005 A comprehensive expression analysis of the Arabidopsis proline-rich extensin-like receptor kinase gene family using bioinformatic and experimental approaches.
|
| 12 |
pancreatic ER stress kinase
(5 times)
|
Biology
(2 times)
|
ATF4 (3 times)
CHOP (3 times)
eIF2alpha (3 times)
|
2010 EIF2alpha and caspase-12 activation are involved in oxygen-glucose-serum deprivation/restoration-induced apoptosis of spinal cord astrocytes.
|
| 13 |
protein kinase-like ER-resident kinase
(5 times)
|
Biophysics
(1 time)
|
ER (5 times)
CHOP (2 times)
UPR (2 times)
|
2005 Hepatitis C virus envelope proteins regulate CHOP via induction of the unfolded protein response.
|
| 14 |
phospho-pancreatic ER kinase
(4 times)
|
Ophthalmology
(2 times)
|
ER (3 times)
eIF-2 alpha (2 times)
eIF2alpha (2 times)
|
2007 Endoplasmic reticulum stress is activated in light-induced retinal degeneration.
|
| 15 |
pancreatic ER kinase-like ER kinase
(3 times)
|
Cardiology
(1 time)
|
ER (2 times)
ATF6 (1 time)
CHOP (1 time)
|
2012 Glucose regulated protein 78 diminishes alpha-synuclein neurotoxicity in a rat model of Parkinson disease.
|
| 16 |
pancreatic EIF2-alpha kinase
(2 times)
|
Allergy and Immunology
(1 time)
|
ATF4 (1 time)
ATG13 (1 time)
ER (1 time)
|
2018 ER-stress regulates macrophage polarization through pancreatic EIF-2alpha kinase.
|
| 17 |
PKR-endoplasmic reticulum-related kinase
(2 times)
|
Psychiatry
(1 time)
|
AD (2 times)
eIF2alpha (1 time)
|
2013 Mechanisms that lessen benefits of beta-secretase reduction in a mouse model of Alzheimer's disease.
|
| 18 |
protein kinase-like ER eukaryotic initiation factor-2alpha kinase
(2 times)
|
Medicine
(1 time)
|
ER (2 times)
AMP (1 time)
ATF6 (1 time)
|
2013 Activation of the unfolded protein response in vascular endothelial cells of nondiabetic obese adults.
|
| 19 |
pancreatic endoplasmic reticulum kinase-like endoplasmic reticulum kinase
(1 time)
|
Molecular Biology
(1 time)
|
ATF (1 time)
BiP (1 time)
CHOP (1 time)
|
2013 PPARgamma-inactive Delta2-troglitazone independently triggers ER stress and apoptosis in breast cancer cells.
|
| 20 |
pancreatic ER eukaryotic translation initiation factor-2a kinase
(1 time)
|
Clinical Laboratory Techniques
(1 time)
|
ATF6 (1 time)
CHOP (1 time)
ER (1 time)
|
2021 Exogenous hydrogen sulfide protects against hepatic ischemia/reperfusion injury by inhibiting endoplasmic reticulum stress and cell apoptosis.
|
| 21 |
parameter estimation via regression with kernels
(1 time)
|
Diagnostic Imaging
(1 time)
|
qMRI (1 time)
|
2018 Dictionary-Free MRI PERK: Parameter Estimation via Regression with Kernels.
|
| 22 |
pathways exist:protein kinase RNA-like ER kinase
(1 time)
|
Medicine
(1 time)
|
ATF4 (1 time)
ATF6 (1 time)
eIF2alpha (1 time)
|
2016 miRNA-1283 Regulates the PERK/ATF4 Pathway in Vascular Injury by Targeting ATF4.
|
| 23 |
PERK and IRE1alpha were upregulated ~2-fold at 70d and remained
(1 time)
|
Neurosciences
(1 time)
|
ALS (1 time)
RG (1 time)
WG (1 time)
|
2015 Activation of the endoplasmic reticulum stress response in skeletal muscle of G93A*SOD1 amyotrophic lateral sclerosis mice.
|
| 24 |
PERK knockdown
(1 time)
|
Dentistry
(1 time)
|
ALP (1 time)
ATF4 (1 time)
BSP (1 time)
|
2021 Endoplasmic reticulum stress response mediated by the PERK-eIF2α-ATF4 pathway is involved in odontoblastic differentiation of human dental pulp cells.
|
| 25 |
PERKDeltaC
(1 time)
|
Biochemistry
(1 time)
|
A/A (1 time)
S/S (1 time)
Ser51Ala (1 time)
|
2006 The roles of translation initiation regulation in ultraviolet light-induced apoptosis.
|
| 26 |
PerkinElmer
(1 time)
|
Gynecology
(1 time)
|
FMF (1 time)
VP (1 time)
|
2018 Risk assessment for preterm preeclampsia in first trimester: Comparison of three calculation algorithms.
|
| 27 |
phospho-extracellular regulated protein kinases
(1 time)
|
Biochemistry
(1 time)
|
ATF6 (1 time)
ER (1 time)
IRE1alpha (1 time)
|
2016 Naringenin ameliorates hypoxia/reoxygenation-induced endoplasmic reticulum stress-mediated apoptosis in H9c2 myocardial cells: involvement in ATF6, IRE1alpha and PERK signaling activation.
|
| 28 |
phospho-PKR-like endoreticulum
(1 time)
|
Neurology
(1 time)
|
CREB (1 time)
ECS (1 time)
GSK-3beta (1 time)
|
2010 Phenylbutyric acid prevents rats from electroconvulsion-induced memory deficit with alterations of memory-related proteins and tau hyperphosphorylation.
|
| 29 |
phosphorylated endoplasmic reticulum-localized eukaryotic initiation factor-2alpha kinase
(1 time)
|
Pathology
(1 time)
|
CHOP (1 time)
|
2007 Aggregated myocilin induces russell bodies and causes apoptosis: implications for the pathogenesis of myocilin-caused primary open-angle glaucoma.
|
| 30 |
PKR-like ER stress kinase
(1 time)
|
Biology
(1 time)
|
ATF4 (1 time)
ER (1 time)
HCC (1 time)
|
2019 Melatonin Increases the Sensitivity of Hepatocellular Carcinoma to Sorafenib through the PERK-ATF4-Beclin1 Pathway.
|
| 31 |
PKR-like ER-associated kinase
(1 time)
|
Anatomy
(1 time)
|
ATF6 (1 time)
BiP (1 time)
CL (1 time)
|
2017 Roles of Grp78 in Female Mammalian Reproduction.
|
| 32 |
PKR-like ER-localized eIF2-alpha kinase
(1 time)
|
Medicine
(1 time)
|
CHOP (1 time)
eIF2 (1 time)
ER (1 time)
|
2013 Endoplasmic reticulum stress contributes to Helicobacter pylori VacA-induced apoptosis.
|
| 33 |
PKR-like ER-regulated kinase
(1 time)
|
Medicine
(1 time)
|
CHOP (1 time)
eIF2alpha (1 time)
ER (1 time)
|
2013 Triglyceride-rich lipoprotein modulates endothelial vascular cell adhesion molecule (VCAM)-1 expression via differential regulation of endoplasmic reticulum stress.
|
| 34 |
PKR-related ER kinase
(1 time)
|
Science
(1 time)
|
ER (1 time)
IRE1 (1 time)
UPR (1 time)
|
2006 The crystal structure of human IRE1 luminal domain reveals a conserved dimerization interface required for activation of the unfolded protein response.
|
| 35 |
protein endoplasmic-reticular-resident kinase
(1 time)
|
Complementary Therapies
(1 time)
|
eIF-2 alpha (1 time)
ER (1 time)
GADD153 (1 time)
|
2013 A Taiwanese Propolis Derivative Induces Apoptosis through Inducing Endoplasmic Reticular Stress and Activating Transcription Factor-3 in Human Hepatoma Cells.
|
| 36 |
Protein kinase receptor-like ER kinase
(1 time)
|
Biology
(1 time)
|
IRE1 (1 time)
|
2019 The role of PERK and IRE1 signaling pathways in excessive fluoride mediated impairment of lymphocytes in rats' spleen invivo and invitro.
|
| 37 |
protein kinase-like ER-integral
(1 time)
|
Molecular Biology
(1 time)
|
ER (1 time)
HRI (1 time)
KO (1 time)
|
2010 Hepatic heme-regulated inhibitor (HRI) eukaryotic initiation factor 2alpha kinase: a protagonist of heme-mediated translational control of CYP2B enzymes and a modulator of basal endoplasmic reticulum stress tone.
|
| 38 |
protein response, the endoplasmic reticulum resident RNA-dependent kinase
(1 time)
|
Neurology
(1 time)
|
---
|
2004 Dominant-negative calcium channel suppression by truncated constructs involves a kinase implicated in the unfolded protein response.
|
| 39 |
protein-PRKR-like ER kinase
(1 time)
|
Cell Biology
(1 time)
|
eIF2alpha (1 time)
ER (1 time)
PI3K (1 time)
|
2018 Chrysin leads to cell death in endometriosis by regulation of endoplasmic reticulum stress and cytosolic calcium level.
|
| 40 |
Providing Effective Resources and Knowledge
(1 time)
|
Family Practice
(1 time)
|
TCI (1 time)
|
2015 Measuring teamwork in primary care: Triangulation of qualitative and quantitative data.
|
A Search Service for Abbreviation / Long Form