1 |
protein kinase RNA-like endoplasmic reticulum kinase
(399 times)
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Biochemistry (53 times)
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ER (196 times) UPR (96 times) CHOP (88 times)
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2001 Characterization of phosphopeptides from protein digests using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and nanoelectrospray quadrupole time-of-flight mass spectrometry.
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2 |
protein kinase RNA-like ER kinase
(266 times)
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Cell Biology (35 times)
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ER (209 times) UPR (84 times) CHOP (72 times)
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2002 Distinct roles of activating transcription factor 6 (ATF6) and double-stranded RNA-activated protein kinase-like endoplasmic reticulum kinase (PERK) in transcription during the mammalian unfolded protein response.
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3 |
PKR-like ER kinase
(169 times)
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Cell Biology (30 times)
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ER (117 times) UPR (60 times) CHOP (41 times)
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2001 Translational control by the ER transmembrane kinase/ribonuclease IRE1 under ER stress.
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4 |
Prospective Evaluation of Radial Keratotomy
(50 times)
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Ophthalmology (32 times)
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RK (3 times) BBR (2 times) IOP (2 times)
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1983 Rationale for and design of the National Eye Institute Prospective Evaluation of Radial Keratotomy (PERK) Study.
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5 |
pancreatic ER kinase
(33 times)
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Neurology (7 times)
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ER (24 times) IRE1 (11 times) UPR (8 times)
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2002 Endoplasmic reticulum stress and the development of diabetes: a review.
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6 |
pancreatic endoplasmic reticulum kinase
(20 times)
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Pharmacology (3 times)
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ER (7 times) UPR (7 times) EAE (4 times)
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2004 Cytoprotection by pre-emptive conditional phosphorylation of translation initiation factor 2.
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7 |
protein kinase
(16 times)
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General Surgery (3 times)
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ER (5 times) ATF6 (3 times) GRP78 (3 times)
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2003 Cycloheximide inhibits neurotoxic responses induced by kainic acid in mice.
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8 |
protein kinase RNA-activated-like ER kinase
(10 times)
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Cell Biology (3 times)
|
ER (10 times) UPR (6 times) CHOP (3 times)
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2012 MicroRNA-30c-2* limits expression of proadaptive factor XBP1 in the unfolded protein response.
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9 |
PKR-like ER protein kinase
(9 times)
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Medicine (2 times)
|
ER (9 times) ATF6 (6 times) IRE1 (6 times)
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2007 [Unfolded protein response: its role in physiology and physiopathology].
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10 |
PKR-like ER-resident kinase
(6 times)
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Virology (2 times)
|
ER (4 times) ATF4 (3 times) UPR (2 times)
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2003 Protein synthesis and endoplasmic reticulum stress can be modulated by the hepatitis C virus envelope protein E2 through the eukaryotic initiation factor 2alpha kinase PERK.
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11 |
proline-rich extensin-like receptor kinase
(6 times)
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Botany (3 times)
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AGP (1 time) BAECs (1 time) BFA (1 time)
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2005 A comprehensive expression analysis of the Arabidopsis proline-rich extensin-like receptor kinase gene family using bioinformatic and experimental approaches.
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12 |
pancreatic ER stress kinase
(5 times)
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Biology (2 times)
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ATF4 (3 times) CHOP (3 times) eIF2alpha (3 times)
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2010 EIF2alpha and caspase-12 activation are involved in oxygen-glucose-serum deprivation/restoration-induced apoptosis of spinal cord astrocytes.
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13 |
protein kinase-like ER-resident kinase
(5 times)
|
Biophysics (1 time)
|
ER (5 times) CHOP (2 times) UPR (2 times)
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2005 Hepatitis C virus envelope proteins regulate CHOP via induction of the unfolded protein response.
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14 |
phospho-pancreatic ER kinase
(4 times)
|
Ophthalmology (2 times)
|
ER (3 times) eIF-2 alpha (2 times) eIF2alpha (2 times)
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2007 Endoplasmic reticulum stress is activated in light-induced retinal degeneration.
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15 |
pancreatic ER kinase-like ER kinase
(3 times)
|
Cardiology (1 time)
|
ER (2 times) ATF6 (1 time) CHOP (1 time)
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2012 Glucose regulated protein 78 diminishes alpha-synuclein neurotoxicity in a rat model of Parkinson disease.
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16 |
pancreatic EIF2-alpha kinase
(2 times)
|
Allergy and Immunology (1 time)
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ATF4 (1 time) ATG13 (1 time) ER (1 time)
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2018 ER-stress regulates macrophage polarization through pancreatic EIF-2alpha kinase.
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17 |
PKR-endoplasmic reticulum-related kinase
(2 times)
|
Psychiatry (1 time)
|
AD (2 times) eIF2alpha (1 time)
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2013 Mechanisms that lessen benefits of beta-secretase reduction in a mouse model of Alzheimer's disease.
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18 |
protein kinase-like ER eukaryotic initiation factor-2alpha kinase
(2 times)
|
Medicine (1 time)
|
ER (2 times) AMP (1 time) ATF6 (1 time)
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2013 Activation of the unfolded protein response in vascular endothelial cells of nondiabetic obese adults.
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19 |
pancreatic endoplasmic reticulum kinase-like endoplasmic reticulum kinase
(1 time)
|
Molecular Biology (1 time)
|
ATF (1 time) BiP (1 time) CHOP (1 time)
|
2013 PPARgamma-inactive Delta2-troglitazone independently triggers ER stress and apoptosis in breast cancer cells.
|
20 |
pancreatic ER eukaryotic translation initiation factor-2a kinase
(1 time)
|
Clinical Laboratory Techniques (1 time)
|
ATF6 (1 time) CHOP (1 time) ER (1 time)
|
2021 Exogenous hydrogen sulfide protects against hepatic ischemia/reperfusion injury by inhibiting endoplasmic reticulum stress and cell apoptosis.
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21 |
parameter estimation via regression with kernels
(1 time)
|
Diagnostic Imaging (1 time)
|
qMRI (1 time)
|
2018 Dictionary-Free MRI PERK: Parameter Estimation via Regression with Kernels.
|
22 |
pathways exist:protein kinase RNA-like ER kinase
(1 time)
|
Medicine (1 time)
|
ATF4 (1 time) ATF6 (1 time) eIF2alpha (1 time)
|
2016 miRNA-1283 Regulates the PERK/ATF4 Pathway in Vascular Injury by Targeting ATF4.
|
23 |
PERK and IRE1alpha were upregulated ~2-fold at 70d and remained
(1 time)
|
Neurosciences (1 time)
|
ALS (1 time) RG (1 time) WG (1 time)
|
2015 Activation of the endoplasmic reticulum stress response in skeletal muscle of G93A*SOD1 amyotrophic lateral sclerosis mice.
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24 |
PERK knockdown
(1 time)
|
Dentistry (1 time)
|
ALP (1 time) ATF4 (1 time) BSP (1 time)
|
2021 Endoplasmic reticulum stress response mediated by the PERK-eIF2α-ATF4 pathway is involved in odontoblastic differentiation of human dental pulp cells.
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25 |
PERKDeltaC
(1 time)
|
Biochemistry (1 time)
|
A/A (1 time) S/S (1 time) Ser51Ala (1 time)
|
2006 The roles of translation initiation regulation in ultraviolet light-induced apoptosis.
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26 |
PerkinElmer
(1 time)
|
Gynecology (1 time)
|
FMF (1 time) VP (1 time)
|
2018 Risk assessment for preterm preeclampsia in first trimester: Comparison of three calculation algorithms.
|
27 |
phospho-extracellular regulated protein kinases
(1 time)
|
Biochemistry (1 time)
|
ATF6 (1 time) ER (1 time) IRE1alpha (1 time)
|
2016 Naringenin ameliorates hypoxia/reoxygenation-induced endoplasmic reticulum stress-mediated apoptosis in H9c2 myocardial cells: involvement in ATF6, IRE1alpha and PERK signaling activation.
|
28 |
phospho-PKR-like endoreticulum
(1 time)
|
Neurology (1 time)
|
CREB (1 time) ECS (1 time) GSK-3beta (1 time)
|
2010 Phenylbutyric acid prevents rats from electroconvulsion-induced memory deficit with alterations of memory-related proteins and tau hyperphosphorylation.
|
29 |
phosphorylated endoplasmic reticulum-localized eukaryotic initiation factor-2alpha kinase
(1 time)
|
Pathology (1 time)
|
CHOP (1 time)
|
2007 Aggregated myocilin induces russell bodies and causes apoptosis: implications for the pathogenesis of myocilin-caused primary open-angle glaucoma.
|
30 |
PKR-like ER stress kinase
(1 time)
|
Biology (1 time)
|
ATF4 (1 time) ER (1 time) HCC (1 time)
|
2019 Melatonin Increases the Sensitivity of Hepatocellular Carcinoma to Sorafenib through the PERK-ATF4-Beclin1 Pathway.
|
31 |
PKR-like ER-associated kinase
(1 time)
|
Anatomy (1 time)
|
ATF6 (1 time) BiP (1 time) CL (1 time)
|
2017 Roles of Grp78 in Female Mammalian Reproduction.
|
32 |
PKR-like ER-localized eIF2-alpha kinase
(1 time)
|
Medicine (1 time)
|
CHOP (1 time) eIF2 (1 time) ER (1 time)
|
2013 Endoplasmic reticulum stress contributes to Helicobacter pylori VacA-induced apoptosis.
|
33 |
PKR-like ER-regulated kinase
(1 time)
|
Medicine (1 time)
|
CHOP (1 time) eIF2alpha (1 time) ER (1 time)
|
2013 Triglyceride-rich lipoprotein modulates endothelial vascular cell adhesion molecule (VCAM)-1 expression via differential regulation of endoplasmic reticulum stress.
|
34 |
PKR-related ER kinase
(1 time)
|
Science (1 time)
|
ER (1 time) IRE1 (1 time) UPR (1 time)
|
2006 The crystal structure of human IRE1 luminal domain reveals a conserved dimerization interface required for activation of the unfolded protein response.
|
35 |
protein endoplasmic-reticular-resident kinase
(1 time)
|
Complementary Therapies (1 time)
|
eIF-2 alpha (1 time) ER (1 time) GADD153 (1 time)
|
2013 A Taiwanese Propolis Derivative Induces Apoptosis through Inducing Endoplasmic Reticular Stress and Activating Transcription Factor-3 in Human Hepatoma Cells.
|
36 |
Protein kinase receptor-like ER kinase
(1 time)
|
Biology (1 time)
|
IRE1 (1 time)
|
2019 The role of PERK and IRE1 signaling pathways in excessive fluoride mediated impairment of lymphocytes in rats' spleen invivo and invitro.
|
37 |
protein kinase-like ER-integral
(1 time)
|
Molecular Biology (1 time)
|
ER (1 time) HRI (1 time) KO (1 time)
|
2010 Hepatic heme-regulated inhibitor (HRI) eukaryotic initiation factor 2alpha kinase: a protagonist of heme-mediated translational control of CYP2B enzymes and a modulator of basal endoplasmic reticulum stress tone.
|
38 |
protein response, the endoplasmic reticulum resident RNA-dependent kinase
(1 time)
|
Neurology (1 time)
|
---
|
2004 Dominant-negative calcium channel suppression by truncated constructs involves a kinase implicated in the unfolded protein response.
|
39 |
protein-PRKR-like ER kinase
(1 time)
|
Cell Biology (1 time)
|
eIF2alpha (1 time) ER (1 time) PI3K (1 time)
|
2018 Chrysin leads to cell death in endometriosis by regulation of endoplasmic reticulum stress and cytosolic calcium level.
|
40 |
Providing Effective Resources and Knowledge
(1 time)
|
Family Practice (1 time)
|
TCI (1 time)
|
2015 Measuring teamwork in primary care: Triangulation of qualitative and quantitative data.
|