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■ Search Result - Abbreviation : PI3K

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Abbreviation: PI3K
Appearance Frequency: 13207 time(s)
Long forms: 54

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Long Form No. Long Form Research Area Co-occurring Abbreviation PubMed/MEDLINE Info. (Year, Title)
phosphatidylinositol 3-kinase
(12941 times)
Neoplasms
(2410 times)
MAPK (1091 times)
mTOR (1007 times)
ERK (854 times)
1990 Phosphorylation of the PDGF receptor beta subunit creates a tight binding site for phosphatidylinositol 3 kinase.
PI3 kinase
(183 times)
Cell Biology
(31 times)
MAPK (13 times)
mTOR (6 times)
VEGF (6 times)
1996 Carbachol inhibits insulin-stimulated phosphatidylinositol 3-kinase activity in SH-SY5Y neuroblastoma cells.
PIK3CA
(17 times)
Neoplasms
(6 times)
3'-UTR (1 time)
AKT1 (1 time)
ASM (1 time)
2005 PIK3CA mutations correlate with hormone receptors, node metastasis, and ERBB2, and are mutually exclusive with PTEN loss in human breast carcinoma.
PI3Kgamma
(7 times)
Biochemistry
(2 times)
PI3Ks (2 times)
ADP (1 time)
GPCRs (1 time)
1996 Phosphopleckstrin inhibits gbetagamma-activable platelet phosphatidylinositol-4,5-bisphosphate 3-kinase.
phosphatidylinositol 3-kinase-dependent
(4 times)
Endocrinology
(2 times)
MAPK (2 times)
NO (2 times)
ERK (1 time)
2005 Gamma-tocotrienol inhibits neoplastic mammary epithelial cell proliferation by decreasing Akt and nuclear factor kappaB activity.
pathway including phosphoinositol-3-kinase
(3 times)
Physiology
(1 time)
BRAFi (1 time)
MEKi (1 time)
PD-L1 (1 time)
2009 Cation currents in human airway epithelial cells induced by infection with influenza A virus.
PI3K/AKT/mTOR
(3 times)
Neoplasms
(3 times)
EMT (1 time)
2015 Targeting drivers of melanoma with synthetic small molecules and phytochemicals.
PI3K-C2beta
(2 times)
Biochemistry
(1 time)
HCV (1 time)
LPA (1 time)
PtdIns3P (1 time)
2005 Class II phosphoinositide 3-kinase defines a novel signaling pathway in cell migration.
PIK3R1
(2 times)
Molecular Biology
(1 time)
PPARgamma (1 time)
PPREs (1 time)
2014 Transcriptional activation of PIK3R1 by PPARgamma in adipocytes.
10  (KIT)-phosphoinositol 3 kinase
(1 time)
Cell Biology
(1 time)
dpp (1 time)
mTORC1 (1 time)
2018 MAPK3/1 participates in the activation of primordial follicles through mTORC1-KITL signaling.
11  3-phosphoinositide-dependent kinase-1
(1 time)
Medicine
(1 time)
CHBP (1 time)
FOXO3a (1 time)
IRI (1 time)
2015 Cyclic helix B peptide inhibits ischemia reperfusion-induced renal fibrosis via the PI3K/Akt/FoxO3a pathway.
12  G(alpha)(i3)-Gbetagamma-phosphoinositide 3-kinase
(1 time)
Molecular Biology
(1 time)
INSL3 (1 time)
RXFP (1 time)
2009 Relaxin family peptide receptor (RXFP1) coupling to G(alpha)i3 involves the C-terminal Arg752 and localization within membrane Raft Microdomains.
13  Gi-Gbetagamma-phosphoinositide 3-kinase
(1 time)
Drug Therapy
(1 time)
beta-AR (1 time)
CaMKII (1 time)
CHF (1 time)
2005 Emerging concepts and therapeutic implications of beta-adrenergic receptor subtype signaling.
14  KL-Kit-PI3 kinase
(1 time)
Endocrinology
(1 time)
GSK-3 (1 time)
2007 Phosphorylation and inactivation of glycogen synthase kinase-3 by soluble kit ligand in mouse oocytes during early follicular development.
15  laminin-DGC-Gbetagamma-phosphatidylinositol 3-kinase
(1 time)
Cell Biology
(1 time)
AP-1 (1 time)
DGC (1 time)
JNK (1 time)
2012 Laminin-alpha1 LG4-5 domain binding to dystroglycan mediates muscle cell survival, growth, and the AP-1 and NF-kappaB transcription factors but also has adverse effects.
16  pan-PI3 kinase
(1 time)
Pulmonary Medicine
(1 time)
BAL (1 time)
IPF (1 time)
mTOR (1 time)
2016 Exploration of a potent PI3 kinase/mTOR inhibitor as a novel anti-fibrotic agent in IPF.
17  pan-PI3K inhibitors
(1 time)
Neoplasms
(1 time)
BC (1 time)
ER (1 time)
mTOR (1 time)
2014 Managing postmenopausal women with hormone receptor-positive advanced breast cancer who progress on endocrine therapies with inhibitors of the PI3K pathway.
18  pathway, the inositol-3 phosphate kinase
(1 time)
Cell Biology
(1 time)
--- 2010 Cyclin A2 confers cisplatin resistance to endometrial carcinoma cells via up-regulation of an Akt-binding protein, periplakin.
19  pathways, i.e., phosphoinositol-3 kinase
(1 time)
Hormones
(1 time)
HIF-1alpha (1 time)
2015 Adipose tissue dysfunction and its effects on tumor metabolism.
20  PDGF-initiated phosphoinositide-3 kinase
(1 time)
Neoplasms
(1 time)
LOH (1 time)
NHERF1 (1 time)
PDGFR (1 time)
2008 Na+/H+ exchanger regulatory factor 1 inhibits platelet-derived growth factor signaling in breast cancer cells.
21  PHB in phophatidylinositol-3-kinase
(1 time)
Biochemistry
(1 time)
ERK (1 time)
MAPK (1 time)
TGF-beta (1 time)
2010 The role of prohibitin in cell signaling.
22  Phosphatidyl-inositol-3,4,5-triphosphate 3-phosphatase and phosphatidylinositol-3 kinase
(1 time)
Behavioral Sciences
(1 time)
CFC (1 time)
DDR2 (1 time)
PP2A (1 time)
2015 Networks of protein kinases and phosphatases in the individual phases of contextual fear conditioning in the C57BL/6J mouse.
23  phosphatidylinositol 3-kinase/serine/threonine kinase
(1 time)
Complementary Therapies
(1 time)
ELISA (1 time)
ERalpha (1 time)
ERP (1 time)
2015 [Effects of acupuncture on PI3K/Akt/mTOR signaling pathway in rats with premature ovarian failure].
24  phosphatidylinositol tallow alcohol 3-kinase
(1 time)
Reproductive Medicine
(1 time)
DA (1 time)
NO (1 time)
p-Akt (1 time)
2018 Icariin improves the sexual function of male mice through the PI3K/AKT/eNOS/NO signalling pathway.
25  phosphatidylinositol-3 kinase p85 subunit
(1 time)
Geriatrics
(1 time)
CR (1 time)
IRS-1 (1 time)
2000 Effect of long-term caloric restriction on GLUT4, phosphatidylinositol-3 kinase p85 subunit, and insulin receptor substrate-1 protein levels in rhesus monkey skeletal muscle.
26  phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
(1 time)
Biochemistry
(1 time)
MYOD1 (2 times)
HIF1A (1 time)
MEF2 (1 time)
2014 Insulin acutely triggers transcription of Slc2a4 gene: participation of the AT-rich, E-box and NFKB-binding sites.
27  phospho-PI3 kinase
(1 time)
MCAO (1 time)
MDA (1 time)
Nrf2 (1 time)
2017 RhGLP-1 (7-36) protects diabetic rats against cerebral ischemia-reperfusion injury via up-regulating expression of Nrf2/HO-1 and increasing the activities of SOD.
28  Phosphoenolpyruvate 3-kinases
(1 time)
Pharmacology
(1 time)
GLUT1 (1 time)
INSR (1 time)
IRS-1 (1 time)
2013 Regulation effects of TZQ-F on adipocyte differentiation and insulin action.
29  phosphoinositide 3'-hydroxykinase
(1 time)
Biochemistry
(1 time)
DMPM (1 time)
PI (1 time)
PIP (1 time)
1995 Interfacial catalysis by phosphoinositide 3'-hydroxykinase.
30  Phosphoinositide 3-kinase Class I
(1 time)
CSC (1 time)
EMT (1 time)
TICs (1 time)
2018 Role of Akt Isoforms Controlling Cancer Stem Cell Survival, Phenotype and Self-Renewal.
31  phosphoinositide 3-kinase/protein kinase B
(1 time)
Medicine
(1 time)
cyto c (1 time)
TBI (1 time)
2012 Salidroside improves behavioral and histological outcomes and reduces apoptosis via PI3K/Akt signaling after experimental traumatic brain injury.
32  phosphorylation including phosphatidylinositol-3-kinase
(1 time)
Reproductive Medicine
(1 time)
CaMKII (1 time)
PKA (1 time)
PP1 (1 time)
2014 PKA and CaMKII mediate PI3K activation in bovine sperm by inhibition of the PKC/PP1 cascade.
33  phosphorylation, IRS/phosphatidylinositol 3-kinase
(1 time)
Gastroenterology
(1 time)
CRP (1 time)
ERK (1 time)
IRS (1 time)
2011 C-reactive protein impairs hepatic insulin sensitivity and insulin signaling in rats: role of mitogen-activated protein kinases.
34  PI3K activation, we used p85alpha
(1 time)
Medicine
(1 time)
PKA (1 time)
2014 The p85 regulatory subunit of PI3K mediates cAMP-PKA and insulin biological effects on MCF-7 cell growth and motility.
35  PI3K derived from a thymic lymphoma, p65
(1 time)
Biology
(1 time)
--- 2000 Increased phosphoinositide 3-kinase activity induces a lymphoproliferative disorder and contributes to tumor generation in vivo.
36  PI3K p110delta
(1 time)
Pulmonary Medicine
(1 time)
BM-Eos (1 time)
2012 The p110delta subunit of PI3K regulates bone marrow-derived eosinophil trafficking and airway eosinophilia in allergen-challenged mice.
37  PI3K regulatory subunit, p65
(1 time)
Biology
(1 time)
--- 2002 A Role for phosphoinositide 3-kinase in the control of cell division and survival during retinal development.
38  PI3K-based immune therapies for transplantation.Phosphatidylinositol-3-kinases
(1 time)
Biology
(1 time)
--- 2017 Regulation of T cell alloimmunity by PI3Kgamma and PI3Kdelta.
39  PI3K-C2 alpha
(1 time)
Biochemistry
(1 time)
PI3Ks (1 time)
2002 Direct effects of caffeine and theophylline on p110 delta and other phosphoinositide 3-kinases. Differential effects on lipid kinase and protein kinase activities.
40  PI3K-C2alpha and PI3K-C2beta
(1 time)
--- 2003 Topographical expression of class IA and class II phosphoinositide 3-kinase enzymes in normal human tissues is consistent with a role in differentiation.
41  PI3K-Deltap85
(1 time)
Biochemistry
(1 time)
--- 2004 Phosphatidylinositol 3-kinase and frabin mediate Cryptosporidium parvum cellular invasion via activation of Cdc42.
42  PI3K-DN
(1 time)
Allergy and Immunology
(1 time)
A/E (1 time)
CTL (1 time)
FasL (1 time)
2003 Differential implication of protein kinase C isoforms in cytotoxic T lymphocyte degranulation and TCR-induced Fas ligand expression.
43  PI3K-H1047R
(1 time)
Molecular Biology
(1 time)
--- 2013 Autophagy restricts proliferation driven by oncogenic phosphatidylinositol 3-kinase in three-dimensional culture.
44  PI3K-IR
(1 time)
Psychopharmacology
(1 time)
ASODN (1 time)
i.c.v (1 time)
MOR (1 time)
2003 [Direct involvement of the supraspinal phosphoinositide 3-kinase/phospholipase C gamma 1 pathway in the mu-opioid receptor agonist-induced supraspinal antinociception in the mouse].
45  PI3K/Akt pathway through recruitment of Grb2/Gab2 followed by p85
(1 time)
Biochemistry
(1 time)
GDNF (1 time)
2000 Signaling complexes and protein-protein interactions involved in the activation of the Ras and phosphatidylinositol 3-kinase pathways by the c-Ret receptor tyrosine kinase.
46  PI3K/mTOR
(1 time)
Molecular Biology
(1 time)
NB (1 time)
2014 Detection of PI3K inhibition in human neuroblastoma using multiplex luminex bead immunoassay: a targeted approach for pathway analysis.
47  PI3K/PTEN signaling axis through dual regulation of both p110
(1 time)
Cell Biology
(1 time)
--- 2010 p85 plays a critical role in controlling flux through the PI3K/PTEN signaling axis through dual regulation of both p110 (PI3K) and PTEN.
48  PI3Kbeta
(1 time)
Hematology
(1 time)
--- 2013 The proline-rich tyrosine kinase Pyk2 regulates platelet integrin alphaIIbbeta3 outside-in signaling.
49  PIK3CA, AKT1, PIK3CG
(1 time)
Neoplasms
(1 time)
MCC (1 time)
MCV (1 time)
TIL (1 time)
2015 UV-Associated Mutations Underlie the Etiology of MCV-Negative Merkel Cell Carcinomas.
50  PIK3R1 and PIK3CA genes, respectively
(1 time)
Neoplasms
(1 time)
BRAF (1 time)
OS (1 time)
SNPs (1 time)
2017 Impact of phosphoinositide-3-kinase and vitamin D3 nuclear receptor single-nucleotide polymorphisms on the outcome of malignant melanoma patients.
51  prediction identified phosphoinositide-3 kinases
(1 time)
Medicine
(1 time)
IDD (1 time)
NP (1 time)
2013 MiR-27a regulates apoptosis in nucleus pulposus cells by targeting PI3K.
52  PtdIns-3-kinase
(1 time)
Biotechnology
(1 time)
FGF (1 time)
MAPK (1 time)
2007 Opposed growth factor signals control protein degradation in muscles of Caenorhabditis elegans.
53  Shc-PI-3 kinase
(1 time)
Hematology
(1 time)
GM-CSF (1 time)
IL-3 (1 time)
SHIP (1 time)
2007 The Shc-binding site of the betac subunit of the GM-CSF/IL-3/IL-5 receptors is a negative regulator of hematopoiesis.
54  species-phosphoinositide3-kinase
(1 time)
Diabetes Mellitus
(1 time)
CUR (1 time)
IL (1 time)
TAECs (1 time)
2017 Curcumin attenuates high glucose-induced inflammatory injury through the reactive oxygen species-phosphoinositide 3-kinase/protein kinase B-nuclear factor-kappaB signaling pathway in rat thoracic aorta endothelial cells.