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■ Search Result - Abbreviation : PI3K

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Abbreviation: PI3K
Appearance Frequency: 15363 time(s)
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Long Form No. Long Form Research Area Co-occurring Abbreviation PubMed/MEDLINE Info. (Year, Title)
phosphatidylinositol 3-kinase
(15063 times)
Neoplasms
(2721 times)
mTOR (1297 times)
MAPK (1243 times)
ERK (961 times)
0 Is There aBenefit of HER2-Positive Breast Cancer Subtype Determination in Clinical Practice?
PI3 kinase
(196 times)
Cell Biology
(33 times)
MAPK (14 times)
mTOR (6 times)
PI (6 times)
1996 Carbachol inhibits insulin-stimulated phosphatidylinositol 3-kinase activity in SH-SY5Y neuroblastoma cells.
PIK3CA
(19 times)
Neoplasms
(7 times)
3'-UTR (1 time)
AKT1 (1 time)
ASM (1 time)
2005 PIK3CA mutations correlate with hormone receptors, node metastasis, and ERBB2, and are mutually exclusive with PTEN loss in human breast carcinoma.
PI3Kgamma
(7 times)
Biochemistry
(2 times)
PI3Ks (2 times)
ADP (1 time)
GPCRs (1 time)
1996 Phosphopleckstrin inhibits gbetagamma-activable platelet phosphatidylinositol-4,5-bisphosphate 3-kinase.
pathway including phosphoinositol-3-kinase
(4 times)
Clinical Laboratory Techniques
(1 time)
ACTA1 (1 time)
BRAFi (1 time)
cdc (1 time)
2009 Cation currents in human airway epithelial cells induced by infection with influenza A virus.
phosphatidylinositol 3-kinase-dependent
(4 times)
Endocrinology
(2 times)
MAPK (2 times)
NO (2 times)
ERK (1 time)
2005 Gamma-tocotrienol inhibits neoplastic mammary epithelial cell proliferation by decreasing Akt and nuclear factor kappaB activity.
PIK3R1
(4 times)
Molecular Biology
(1 time)
GO (1 time)
HFD (1 time)
lepa (1 time)
2014 Transcriptional activation of PIK3R1 by PPARgamma in adipocytes.
PI3K/AKT/mTOR
(3 times)
Neoplasms
(3 times)
EMT (1 time)
2015 Targeting drivers of melanoma with synthetic small molecules and phytochemicals.
p-PI3K
(2 times)
Communicable Diseases
(1 time)
ABCA1 (1 time)
2018 microRNA-107 inhibits gastric cancer cell proliferation and metastasis by targeting PI3K/AKT pathway.
10  phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
(2 times)
Neoplasms
(1 time)
MYOD1 (2 times)
GAS5 (1 time)
HIF1A (1 time)
2014 Insulin acutely triggers transcription of Slc2a4 gene: participation of the AT-rich, E-box and NFKB-binding sites.
11  PI3K-C2beta
(2 times)
Cell Biology
(1 time)
HCV (1 time)
LPA (1 time)
PtdIns3P (1 time)
2005 Class II phosphoinositide 3-kinase defines a novel signaling pathway in cell migration.
12  PtdIns 3 kinases
(2 times)
Biotechnology
(1 time)
FGF (1 time)
MAPK (1 time)
PI3,4,5P3 (1 time)
2007 Opposed growth factor signals control protein degradation in muscles of Caenorhabditis elegans.
13  (KIT)-phosphoinositol 3 kinase
(1 time)
Cell Biology
(1 time)
dpp (1 time)
mTORC1 (1 time)
2018 MAPK3/1 participates in the activation of primordial follicles through mTORC1-KITL signaling.
14  3-phosphoinositide-dependent kinase-1
(1 time)
Medicine
(1 time)
CHBP (1 time)
FOXO3a (1 time)
IRI (1 time)
2015 Cyclic helix B peptide inhibits ischemia reperfusion-induced renal fibrosis via the PI3K/Akt/FoxO3a pathway.
15  alpha5beta1-phosphatidylinositol-3-kinase
(1 time)
Biomedical Engineering
(1 time)
Gel-HA (1 time)
PDA (1 time)
RD (1 time)
2019 Mussel-inspired injectable hydrogel and its counterpart for actuating proliferation and neuronal differentiation of retinal progenitor cells.
16  EGFR-Ras-PI 3 kinase
(1 time)
Antioxidants
(1 time)
CK2 (1 time)
EGFR (1 time)
ER (1 time)
2019 Mechanism of Rapid Nuclear Factor-E2-Related Factor 2 (Nrf2) Activation via Membrane-Associated Estrogen Receptors: Roles of NADPH Oxidase 1, Neutral Sphingomyelinase 2 and Epidermal Growth Factor Receptor (EGFR).
17  G(alpha)(i3)-Gbetagamma-phosphoinositide 3-kinase
(1 time)
Molecular Biology
(1 time)
INSL3 (1 time)
RXFP (1 time)
2009 Relaxin family peptide receptor (RXFP1) coupling to G(alpha)i3 involves the C-terminal Arg752 and localization within membrane Raft Microdomains.
18  Gi-Gbetagamma-phosphoinositide 3-kinase
(1 time)
Drug Therapy
(1 time)
beta-AR (1 time)
CaMKII (1 time)
CHF (1 time)
2005 Emerging concepts and therapeutic implications of beta-adrenergic receptor subtype signaling.
19  KL-Kit-PI3 kinase
(1 time)
Endocrinology
(1 time)
GSK-3 (1 time)
2007 Phosphorylation and inactivation of glycogen synthase kinase-3 by soluble kit ligand in mouse oocytes during early follicular development.
20  laminin-DGC-Gbetagamma-phosphatidylinositol 3-kinase
(1 time)
Cell Biology
(1 time)
AP-1 (1 time)
DGC (1 time)
JNK (1 time)
2012 Laminin-alpha1 LG4-5 domain binding to dystroglycan mediates muscle cell survival, growth, and the AP-1 and NF-kappaB transcription factors but also has adverse effects.
21  pan-PI3 kinase
(1 time)
Pulmonary Medicine
(1 time)
BAL (1 time)
IPF (1 time)
mTOR (1 time)
2016 Exploration of a potent PI3 kinase/mTOR inhibitor as a novel anti-fibrotic agent in IPF.
22  pan-PI3K inhibitors
(1 time)
Neoplasms
(1 time)
BC (1 time)
ER (1 time)
mTOR (1 time)
2014 Managing postmenopausal women with hormone receptor-positive advanced breast cancer who progress on endocrine therapies with inhibitors of the PI3K pathway.
23  pathway, the inositol-3 phosphate kinase
(1 time)
Cell Biology
(1 time)
--- 2010 Cyclin A2 confers cisplatin resistance to endometrial carcinoma cells via up-regulation of an Akt-binding protein, periplakin.
24  pathways, i.e., phosphoinositol-3 kinase
(1 time)
Hormones
(1 time)
HIF-1alpha (1 time)
2015 Adipose tissue dysfunction and its effects on tumor metabolism.
25  PDGF-initiated phosphoinositide-3 kinase
(1 time)
Neoplasms
(1 time)
LOH (1 time)
NHERF1 (1 time)
PDGFR (1 time)
2008 Na+/H+ exchanger regulatory factor 1 inhibits platelet-derived growth factor signaling in breast cancer cells.
26  PHB in phophatidylinositol-3-kinase
(1 time)
Biochemistry
(1 time)
ERK (1 time)
MAPK (1 time)
TGF-beta (1 time)
2010 The role of prohibitin in cell signaling.
27  Phosphatidyl-inositol-3,4,5-triphosphate 3-phosphatase and phosphatidylinositol-3 kinase
(1 time)
Behavioral Sciences
(1 time)
CFC (1 time)
DDR2 (1 time)
PP2A (1 time)
2015 Networks of protein kinases and phosphatases in the individual phases of contextual fear conditioning in the C57BL/6J mouse.
28  phosphatidylinositol 3-kinase/serine/threonine kinase
(1 time)
Complementary Therapies
(1 time)
ELISA (1 time)
ERalpha (1 time)
ERP (1 time)
2015 [Effects of acupuncture on PI3K/Akt/mTOR signaling pathway in rats with premature ovarian failure].
29  phosphatidylinositol tallow alcohol 3-kinase
(1 time)
Reproductive Medicine
(1 time)
DA (1 time)
NO (1 time)
p-AKT (1 time)
2018 Icariin improves the sexual function of male mice through the PI3K/AKT/eNOS/NO signalling pathway.
30  phosphatidylinositol-3 kinase p85 subunit
(1 time)
Geriatrics
(1 time)
CR (1 time)
IRS-1 (1 time)
2000 Effect of long-term caloric restriction on GLUT4, phosphatidylinositol-3 kinase p85 subunit, and insulin receptor substrate-1 protein levels in rhesus monkey skeletal muscle.
31  phospho-PI3 kinase
(1 time)
MCAO (1 time)
MDA (1 time)
Nrf2 (1 time)
2017 RhGLP-1 (7-36) protects diabetic rats against cerebral ischemia-reperfusion injury via up-regulating expression of Nrf2/HO-1 and increasing the activities of SOD.
32  Phosphoenolpyruvate 3-kinases
(1 time)
Pharmacology
(1 time)
GLUT1 (1 time)
INSR (1 time)
IRS-1 (1 time)
2013 Regulation effects of TZQ-F on adipocyte differentiation and insulin action.
33  phosphoinositide 3'-hydroxykinase
(1 time)
Biochemistry
(1 time)
DMPM (1 time)
PI (1 time)
PIP (1 time)
1995 Interfacial catalysis by phosphoinositide 3'-hydroxykinase.
34  Phosphoinositide 3-kinase Class I
(1 time)
CSC (1 time)
EMT (1 time)
TICs (1 time)
2018 Role of Akt Isoforms Controlling Cancer Stem Cell Survival, Phenotype and Self-Renewal.
35  phosphoinositide 3-kinase-related protein kinase
(1 time)
Chemistry
(1 time)
CP (1 time)
EMT (1 time)
NF-B (1 time)
2020 Association of the Epithelial-Mesenchymal Transition (EMT) with Cisplatin Resistance.
36  phosphoinositide 3-kinase/protein kinase B
(1 time)
Medicine
(1 time)
cyto c (1 time)
TBI (1 time)
2012 Salidroside improves behavioral and histological outcomes and reduces apoptosis via PI3K/Akt signaling after experimental traumatic brain injury.
37  phosphoinositides by the classIIphosphatidylinositol 3-kinase
(1 time)
Biochemistry
(1 time)
PX (1 time)
2018 Molecular Basis for Membrane Recruitment by the PX and C2 Domains of Class II Phosphoinositide 3-Kinase-C2alpha.
38  phosphoinositide‑3‑kinase regulatory subunit 1
(1 time)
Molecular Biology
(1 time)
--- 2018 MicroRNA‑148a inhibition protects against ovariectomy‑induced osteoporosis through PI3K/AKT signaling by estrogen receptor alpha.
39  phosphorylation including phosphatidylinositol-3-kinase
(1 time)
Reproductive Medicine
(1 time)
CaMKII (1 time)
PKA (1 time)
PP1 (1 time)
2014 PKA and CaMKII mediate PI3K activation in bovine sperm by inhibition of the PKC/PP1 cascade.
40  phosphorylation, IRS/phosphatidylinositol 3-kinase
(1 time)
Gastroenterology
(1 time)
CRP (1 time)
ERK (1 time)
IRS (1 time)
2011 C-reactive protein impairs hepatic insulin sensitivity and insulin signaling in rats: role of mitogen-activated protein kinases.
41  PI3K activation, we used p85alpha
(1 time)
Medicine
(1 time)
PKA (1 time)
2014 The p85 regulatory subunit of PI3K mediates cAMP-PKA and insulin biological effects on MCF-7 cell growth and motility.
42  PI3K derived from a thymic lymphoma, p65
(1 time)
Biology
(1 time)
--- 2000 Increased phosphoinositide 3-kinase activity induces a lymphoproliferative disorder and contributes to tumor generation in vivo.
43  PI3K p110delta
(1 time)
Pulmonary Medicine
(1 time)
BM-Eos (1 time)
2012 The p110delta subunit of PI3K regulates bone marrow-derived eosinophil trafficking and airway eosinophilia in allergen-challenged mice.
44  PI3K regulatory subunit, p65
(1 time)
Biology
(1 time)
--- 2002 A Role for phosphoinositide 3-kinase in the control of cell division and survival during retinal development.
45  PI3K-based immune therapies for transplantation.Phosphatidylinositol-3-kinases
(1 time)
Biology
(1 time)
--- 2017 Regulation of T cell alloimmunity by PI3Kgamma and PI3Kdelta.
46  PI3K-C2 alpha
(1 time)
Biochemistry
(1 time)
PI3Ks (1 time)
2002 Direct effects of caffeine and theophylline on p110 delta and other phosphoinositide 3-kinases. Differential effects on lipid kinase and protein kinase activities.
47  PI3K-C2alpha and PI3K-C2beta
(1 time)
--- 2003 Topographical expression of class IA and class II phosphoinositide 3-kinase enzymes in normal human tissues is consistent with a role in differentiation.
48  PI3K-Deltap85
(1 time)
Biochemistry
(1 time)
--- 2004 Phosphatidylinositol 3-kinase and frabin mediate Cryptosporidium parvum cellular invasion via activation of Cdc42.
49  PI3K-DN
(1 time)
Allergy and Immunology
(1 time)
A/E (1 time)
CTL (1 time)
FasL (1 time)
2003 Differential implication of protein kinase C isoforms in cytotoxic T lymphocyte degranulation and TCR-induced Fas ligand expression.
50  PI3K-H1047R
(1 time)
Molecular Biology
(1 time)
--- 2013 Autophagy restricts proliferation driven by oncogenic phosphatidylinositol 3-kinase in three-dimensional culture.
51  PI3K-IR
(1 time)
Psychopharmacology
(1 time)
ASODN (1 time)
i.c.v (1 time)
MOR (1 time)
2003 [Direct involvement of the supraspinal phosphoinositide 3-kinase/phospholipase C gamma 1 pathway in the mu-opioid receptor agonist-induced supraspinal antinociception in the mouse].
52  PI3K/Akt pathway through recruitment of Grb2/Gab2 followed by p85
(1 time)
Biochemistry
(1 time)
GDNF (1 time)
2000 Signaling complexes and protein-protein interactions involved in the activation of the Ras and phosphatidylinositol 3-kinase pathways by the c-Ret receptor tyrosine kinase.
53  PI3K/mTOR
(1 time)
Molecular Biology
(1 time)
NB (1 time)
2014 Detection of PI3K inhibition in human neuroblastoma using multiplex luminex bead immunoassay: a targeted approach for pathway analysis.
54  PI3K/PTEN signaling axis through dual regulation of both p110
(1 time)
Cell Biology
(1 time)
--- 2010 p85 plays a critical role in controlling flux through the PI3K/PTEN signaling axis through dual regulation of both p110 (PI3K) and PTEN.
55  PI3Kalpha
(1 time)
Neoplasms
(1 time)
PDAC (1 time)
2020 Atypical KRASG12R Mutant Is Impaired in PI3K Signaling and Macropinocytosis in Pancreatic Cancer.
56  PI3Kbeta
(1 time)
Hematology
(1 time)
--- 2013 The proline-rich tyrosine kinase Pyk2 regulates platelet integrin alphaIIbbeta3 outside-in signaling.
57  PI3Kdelta
(1 time)
Allergy and Immunology
(1 time)
CLL (1 time)
2019 The PI3K p110delta Isoform Inhibitor Idelalisib Preferentially Inhibits Human Regulatory T Cell Function.
58  PI3Kp110alpha
(1 time)
Neoplasms
(1 time)
OSCC (1 time)
2020 Selective inhibition of PI3K110alpha as a novel therapeutic strategy for cetuximab‑resistant oral squamous cell carcinoma.
59  PIK3CA, AKT1, and PTEN
(1 time)
Neoplasms
(1 time)
GIST (1 time)
LOH (1 time)
OG (1 time)
2019 Driver gene alterations and activated signaling pathways toward malignant progression of gastrointestinal stromal tumors.
60  PIK3CA, AKT1, PIK3CG
(1 time)
Neoplasms
(1 time)
MCC (1 time)
MCV (1 time)
TIL (1 time)
2015 UV-Associated Mutations Underlie the Etiology of MCV-Negative Merkel Cell Carcinomas.
61  PIK3CA, TSC1 and ATM
(1 time)
Neoplasms
(1 time)
NGS (1 time)
PC (1 time)
2019 Genetic profiling as a clinical tool in advanced parathyroid carcinoma.
62  PIK3R1 and PIK3CA genes, respectively
(1 time)
Neoplasms
(1 time)
BRAF (1 time)
OS (1 time)
SNPs (1 time)
2017 Impact of phosphoinositide-3-kinase and vitamin D3 nuclear receptor single-nucleotide polymorphisms on the outcome of malignant melanoma patients.
63  plaque, including phosphatidylinositol-3 kinase
(1 time)
Medicine
(1 time)
CAD (1 time)
HIF-1alpha (1 time)
HUVEC (1 time)
2019 [Role of miR-106b-5p in the regulation of gene profiles in endothelial cells].
64  prediction identified phosphoinositide-3 kinases
(1 time)
Medicine
(1 time)
IDD (1 time)
NP (1 time)
2013 MiR-27a regulates apoptosis in nucleus pulposus cells by targeting PI3K.
65  Shc-PI-3 kinase
(1 time)
Hematology
(1 time)
GM-CSF (1 time)
IL-3 (1 time)
SHIP (1 time)
2007 The Shc-binding site of the betac subunit of the GM-CSF/IL-3/IL-5 receptors is a negative regulator of hematopoiesis.
66  species-phosphoinositide3-kinase
(1 time)
Diabetes Mellitus
(1 time)
CUR (1 time)
IL (1 time)
TAECs (1 time)
2018 Curcumin attenuates high glucose-induced inflammatory injury through the reactive oxygen species-phosphoinositide 3-kinase/protein kinase B-nuclear factor-kappaB signaling pathway in rat thoracic aorta endothelial cells.
67  TNF-alpha-mediated-phosphatidylinositol-3-kinase
(1 time)
Chemistry
(1 time)
CDDO-Me (1 time)
eNOS (1 time)
NF-kappaB (1 time)
2019 CDDO-Me Attenuates Vasogenic Edema and Astroglial Death by Regulating NF-kappaB p65 Phosphorylations and Nrf2 Expression Following Status Epilepticus.