| 1 |
paclitaxel
(2466 times)
|
Pharmacology
(574 times)
|
MDR (117 times)
DOX (103 times)
NPs (100 times)
|
1997 Phase I trial and pharmacologic trial of sequences of paclitaxel and topotecan in previously treated ovarian epithelial malignancies: a Gynecologic Oncology Group study.
|
| 2 |
pertussis toxin
(1834 times)
|
Biochemistry
(331 times)
|
PKC (154 times)
PLC (105 times)
CTX (94 times)
|
1985 Pertussis toxin reverses adenosine inhibition of neuronal glutamate release.
|
| 3 |
pentoxifylline
(851 times)
|
Pharmacology
(113 times)
|
TNF-alpha (103 times)
TNF (62 times)
LPS (47 times)
|
1984 Filterability of subpopulations of leukocytes: effect of pentoxifylline.
|
| 4 |
picrotoxin
(178 times)
|
Neurology
(71 times)
|
GABA (41 times)
PTZ (18 times)
BIC (14 times)
|
1980 Pharmacological dissection of pyloric network of the lobster stomatogastric ganglion using picrotoxin.
|
| 5 |
pneumothorax
(120 times)
|
Pulmonary Medicine
(21 times)
|
CT (20 times)
US (18 times)
CXR (10 times)
|
1988 Prediction of pneumothorax rate in percutaneous needle aspiration of the lung.
|
| 6 |
palytoxin
(88 times)
|
Pharmacology
(32 times)
|
TTX (7 times)
OA (4 times)
CA (2 times)
|
1975 Palytoxin: effects on contractility and 45Ca2+ uptake in isolated ventricle strips.
|
| 7 |
pentraxin
(31 times)
|
Allergy and Immunology
(4 times)
|
IL (8 times)
CRP (4 times)
BMI (3 times)
|
2002 A malaria scavenger receptor-like protein essential for parasite development.
|
| 8 |
piritrexim
(29 times)
|
Chemistry
(11 times)
|
DHFR (13 times)
MTX (8 times)
TMP (8 times)
|
1987 Initial clinical studies of piritrexim.
|
| 9 |
pectenotoxin
(15 times)
|
Toxicology
(5 times)
|
OA (8 times)
YTX (5 times)
AZA (4 times)
|
1998 Identification and Characterization of Pectenotoxin (PTX) 4 and PTX7 as Spiroketal Stereoisomers of Two Previously Reported Pectenotoxins.
|
| 10 |
pemetrexed
(7 times)
|
Neoplasms
(1 time)
|
5,10-meTHF (1 time)
AICAR (1 time)
AMPK (1 time)
|
2013 Folic acid uptake by the human syncytiotrophoblast is affected by gestational diabetes, hyperleptinemia, and TNF-alpha.
|
| 11 |
nab-paclitaxel
(6 times)
|
Antineoplastic Agents
(5 times)
|
CT (2 times)
OS (2 times)
PFS (2 times)
|
2012 [A case report of liver metastasis of breast cancer successfully treated by hepatic arterial infusion of docetaxel and systemic administration of nab-paclitaxel].
|
| 12 |
pumiliotoxin
(3 times)
|
Toxicology
(2 times)
|
---
|
1981 Inhibition of calcium-dependent ATPase from sarcoplasmic reticulum by a new class of indolizidine alkaloids, pumiliotoxins A, B, and 251D.
|
| 13 |
passive targeting of paclitaxel
(2 times)
|
Chemistry
(2 times)
|
2AAECM (2 times)
HEAA (2 times)
NGs (2 times)
|
2014 pH and glutathion-responsive hydrogel for localized delivery of paclitaxel.
|
| 14 |
pemetrexed diacid
(2 times)
|
Pharmacology
(1 time)
|
CLSM (1 time)
DSC (1 time)
FT-IR (1 time)
|
2017 Lipid drug conjugate nanoparticle as a potential nanocarrier for the oral delivery of pemetrexed diacid: Formulation design, characterization, ex vivo, and in vivo assessment.
|
| 15 |
pertussis toxin-sensitive
(2 times)
|
Psychopharmacology
(1 time)
|
G protein (1 time)
LC (1 time)
NE (1 time)
|
1992 Pertussis toxin-mediated ribosylation of G proteins blocks the hypnotic response to an alpha 2-agonist in the locus coeruleus of the rat.
|
| 16 |
polymer-paclitaxel
(2 times)
|
Biomimetics
(1 time)
|
MRI (1 time)
RAFT (1 time)
|
2016 Construction of polymer-paclitaxel conjugate linked via a disulfide bond.
|
| 17 |
prepared to carry paclitaxel
(2 times)
|
Chemistry
(1 time)
|
ATP (1 time)
FA (1 time)
FSST (1 time)
|
2011 Preparation and in vitro properties of redox-responsive polymeric nanoparticles for paclitaxel delivery.
|
| 18 |
proposed treatment with pentoxifylline
(2 times)
|
Pulmonary Medicine
(1 time)
|
FTE (1 time)
ORN (1 time)
|
1994 [Effect of pentoxifylline on respiratory distress syndrome in dogs].
|
| 19 |
PTX-DCMs
(2 times)
|
Biomedical Engineering
(1 time)
|
DCMs (1 time)
DCs (1 time)
LPS (1 time)
|
2011 Well-defined, reversible disulfide cross-linked micelles for on-demand paclitaxel delivery.
|
| 20 |
8-(3-phenylpropyl)-1,3,7-triethylxanthine
(1 time)
|
Toxicology
(1 time)
|
LDH (1 time)
|
2018 8-(3-phenylpropyl)-1,3,7-triethylxanthine is a synthetic caffeine substitute with stronger metabolic modulator activity.
|
| 21 |
anti-palytoxin
(1 time)
|
Toxicology
(1 time)
|
---
|
2003 Ostreopsis sp., a possible origin of palytoxin (PTX) in parrotfish Scarus ovifrons.
|
| 22 |
delta-philanthotoxin
(1 time)
|
Pharmacology
(1 time)
|
---
|
1982 delta-Philanthotoxin, a semi-irreversible blocker of ion-channels.
|
| 23 |
drug-paclitaxel
(1 time)
|
Biomedical Engineering
(1 time)
|
HNP (1 time)
HTCC (1 time)
|
2013 Codelivery of mTERT siRNA and paclitaxel by chitosan-based nanoparticles promoted synergistic tumor suppression.
|
| 24 |
paclitaxel alone
(1 time)
|
Health Services
(1 time)
|
ACD (1 time)
ACP (1 time)
CIPN (1 time)
|
2012 Taxane-induced peripheral neuropathy and health-related quality of life in postoperative breast cancer patients undergoing adjuvant chemotherapy: N-SAS BC 02, a randomized clinical trial.
|
| 25 |
paclitaxel based endovascular treatment
(1 time)
|
General Surgery
(1 time)
|
CLTI (1 time)
DCBs (1 time)
DESs (1 time)
|
2020 Paclitaxel and Mortality Following Peripheral Angioplasty: An Adjusted and Case Matched Multicentre Analysis.
|
| 26 |
paclitaxel group
(1 time)
|
Complementary Therapies
(1 time)
|
BZYQ (1 time)
NC (1 time)
TC (1 time)
|
2014 Bu-zhong-yi-qi pill alleviate the chemotherapy-related fatigue in 4 T1 murine breast cancer model.
|
| 27 |
paclitaxel-coated
(1 time)
|
Cardiology
(1 time)
|
BMS (1 time)
OCT (1 time)
PLIA (1 time)
|
2016 Optical coherence tomography study of chronic-phase vessel healing after implantation of bare metal and paclitaxel-eluting self-expanding nitinol stents in the superficial femoral artery.
|
| 28 |
paclitaxel-eluting stent
(1 time)
|
General Surgery
(1 time)
|
CLI (1 time)
DES (1 time)
EVT (1 time)
|
2016 Incidence and its characteristics of repetition of reintervention after drug-eluting stent implantation for femoropopliteal lesion.
|
| 29 |
palytoxin toxin
(1 time)
|
Biology
(1 time)
|
PMC (1 time)
|
2013 Probabilistic model checking analysis of palytoxin effects on cell energy reactions of the Na+/K+-ATPase.
|
| 30 |
particle that contained paclitaxel
(1 time)
|
Breast Neoplasms
(1 time)
|
ALG (1 time)
HPLC (1 time)
TEM (1 time)
|
2016 Synthesis, Structural Characterization, and Preclinical Efficacy of a Novel Paclitaxel-Loaded Alginate Nanoparticle for Breast Cancer Treatment.
|
| 31 |
particularly the methylxanthines: caffeine, pentoxifylline
(1 time)
|
Biology
(1 time)
|
HED (1 time)
PDE inhibitors (1 time)
RCTs (1 time)
|
2017 Phosphodiesterase Inhibitors (PDE Inhibitors) and Male Reproduction.
|
| 32 |
patients treated with pentoxifylline
(1 time)
|
Transplantation
(1 time)
|
HPT (1 time)
|
1997 Pentoxifylline, ciprofloxacin and prednisone failed to prevent transplant-related toxicities in bone marrow transplant recipients and were associated with an increased incidence of infectious complications.
|
| 33 |
PEG-PLA to encapsulate paclitaxel
(1 time)
|
Nanotechnology
(1 time)
|
IF-7 (1 time)
|
2019 A carbohydrate mimetic peptide modified size-shrinkable micelle nanocluster for anti-tumor targeting and penetrating drug delivery.
|
| 34 |
pentaxin-related gene
(1 time)
|
Molecular Biology
(1 time)
|
BKLF (1 time)
OSF-2 (1 time)
|
2004 Comparable transforming capacities and differential gene expression patterns of variant FUS/CHOP fusion transcripts derived from soft tissue liposarcomas.
|
| 35 |
Pentoxyfylline drug
(1 time)
|
Drug Therapy
(1 time)
|
Cbp (1 time)
|
2015 Osteogenic effect of locally applied Pentoxyfilline gel: in vitro and in vivo evaluations.
|
| 36 |
peritoneal metastasis were administered systemic chemotherapy first including S-1+paclitaxel
(1 time)
|
Antineoplastic Agents
(1 time)
|
---
|
2010 [Strategy of treatment for gastric cancer with peritoneal metastasis].
|
| 37 |
Pertussis toxin treatment
(1 time)
|
Drug Therapy
(1 time)
|
IBMX (1 time)
PGASMC (1 time)
SHR (1 time)
|
1998 Guanine nucleotide-binding inhibitory protein-mediated inhibition of adenylyl cyclase is enhanced in spontaneously hypertensive rat preglomerular arteriolar smooth muscle cells.
|
| 38 |
PGG-PTX molecules at f
(1 time)
|
Molecular Biology
(1 time)
|
MD (1 time)
PGG-PTX (1 time)
RMSD (1 time)
|
2012 Effects of solution concentration on the physicochemical properties of a polymeric anticancer therapeutic.
|
| 39 |
Pharmacological treatment with picrotoxin
(1 time)
|
Biology
(1 time)
|
EPSPs (1 time)
IPSPs (1 time)
|
2005 Effects of pharmacological treatment and photoinactivation on the directional responses of an insect neuron.
|
| 40 |
philanthotoxin
(1 time)
|
Pharmacology
(1 time)
|
---
|
1992 Philanthotoxins block glutamatergic transmission in rat hippocampus--I. Reduction of high affinity glutamate uptake demonstrated by light microscopy surface autoradiography.
|
| 41 |
phosphate, subtotal NX rats parathyroidectomized
(1 time)
|
Medicine
(1 time)
|
---
|
1978 A micropuncture study of renal phosphate transport in rats with chronic renal failure and secondary hyperparathyroidism.
|
| 42 |
picrotoxin-induced
(1 time)
|
Psychopharmacology
(1 time)
|
---
|
1983 Facilitation of diazepam action by anticonvulsant agents against picrotoxin induced convulsions.
|
| 43 |
pipretixin
(1 time)
|
Antineoplastic Agents
(1 time)
|
LTX (1 time)
PPAT (1 time)
|
2019 In Silico Structure Modeling and Molecular Docking Analysis of Phosphoribosyl Pyrophosphate Amidotransferase (PPAT) with Antifolate Inhibitors.
|
| 44 |
polyester to encapsulate chemotherapeutic paclitaxel
(1 time)
|
Biomimetics
(1 time)
|
HCC (1 time)
PHB (1 time)
STC2 (1 time)
|
2018 Overcoming STC2 mediated drug resistance through drug and gene co-delivery by PHB-PDMAEMA cationic polyester in liver cancer cells.
|
| 45 |
possible that pentoxifilline
(1 time)
|
Medicine
(1 time)
|
ACEI (1 time)
DPE (1 time)
RAAS (1 time)
|
2008 [Clinical state of a patient with nephrotic proteinuria successfully treated with combined therapy with angiotensin II receptor antagonists and angiotensin II converting enzyme inhibitors and pentoxifylline].
|
| 46 |
postconventional transbronchial biopsy pneumothorax
(1 time)
|
Respiratory Tract Diseases
(1 time)
|
SL (1 time)
TBLCB (1 time)
TUS (1 time)
|
2019 Protocolized Thoracic Ultrasonography in Transbronchial Lung Cryobiopsies: A Potential Role as an Exclusion Study for Pneumothorax.
|
| 47 |
potential to cause pneumothorax
(1 time)
|
Traumatology
(1 time)
|
CI (1 time)
|
2009 Delayed pneumothorax after stab wound to thorax and upper abdomen: Truth or myth?
|
| 48 |
Pralatrexate
(1 time)
|
Neoplasms
(1 time)
|
ALP (1 time)
ALT (1 time)
AST (1 time)
|
2019 Clinical efficacy and mechanism of Pralatrexate combined with Palbociclib Isethionate in treatment of bladder cancer patients.
|
| 49 |
pre-TXP parathyroidectomy
(1 time)
|
Transplantation
(1 time)
|
Ca (1 time)
PTH (1 time)
|
2007 Elevated calcium phosphate product after renal transplantation is a risk factor for graft failure.
|
| 50 |
predicting the risk of pneumothorax
(1 time)
|
Pulmonary Medicine
(1 time)
|
FNA (1 time)
|
1993 Pneumothorax with fine-needle aspiration of thoracic lesions. Is spirometry a predictor?
|
| 51 |
prepared the paclitaxel
(1 time)
|
Biochemistry
(1 time)
|
LIFU (1 time)
NPs (1 time)
|
2018 An experimental study of ovarian cancer imaging and therapy by paclitaxel-loaded phase-transformation lipid nanoparticles combined with low-intensity focused ultrasound.
|
| 52 |
present study is to evaluate the inhibitory effects of taxol
(1 time)
|
Rheumatology
(1 time)
|
C II (1 time)
CFA (1 time)
CIA (1 time)
|
2019 Taxol alleviates collagen-induced arthritis in mice by inhibiting the formation of microvessels.
|
| 53 |
present study on understanding the taxol
(1 time)
|
Molecular Biology
(1 time)
|
BSA (1 time)
DFT (1 time)
EEM (1 time)
|
2019 Exploring the Binding Interaction Mechanism of Taxol in beta-Tubulin and Bovine Serum Albumin: A Biophysical Approach.
|
| 54 |
previously that derivatives of pentoxifylline
(1 time)
|
Biophysics
(1 time)
|
MDR (1 time)
P-gp (1 time)
PTX-UHM (1 time)
|
2005 Prolongation of pentoxifylline aliphatic side chain positively affects the reversal of P-glycoprotein-mediated multidrug resistance in L1210/VCR line cells.
|
| 55 |
primary nude mouse tumor xenograft
(1 time)
|
Neoplasms
(1 time)
|
BM (1 time)
HDCT (1 time)
HR-NB (1 time)
|
2009 Fenretinide-induced caspase-8 activation and apoptosis in an established model of metastatic neuroblastoma.
|
| 56 |
Prior to development of nab-paclitaxel
(1 time)
|
|
5-FU (1 time)
GEM (1 time)
|
2018 Phase I study of third-line palliative chemotherapy with low dose paclitaxel for pancreatic cancer.
|
| 57 |
progenitor toxin
(1 time)
|
Microbiology
(1 time)
|
BoNT (1 time)
|
2003 Structural analysis by X-ray crystallography and calorimetry of a haemagglutinin component (HA1) of the progenitor toxin from Clostridium botulinum.
|
| 58 |
properties to systemically co-deliver paclitaxel
(1 time)
|
Nanotechnology
(1 time)
|
CCK-8 (1 time)
FBS (1 time)
NPs (1 time)
|
2018 Smart polymeric nanoparticles with pH-responsive and PEG-detachable properties for co-delivering paclitaxel and survivin siRNA to enhance antitumor outcomes.
|
| 59 |
prospectively tested pentoxifylline
(1 time)
|
Nephrology
(1 time)
|
CIN (1 time)
|
2012 Efficacy of pentoxifylline in prevention of contrast-induced nephropathy in angioplasty patients.
|
| 60 |
proximal tubule segments from normal, parathyroidectomized
(1 time)
|
Physiology
(1 time)
|
Ca (1 time)
PTH (1 time)
|
1986 Na,K-ATPase activity and 25(OH)vitamin D3 hydroxylation in rat proximal tubules.
|
| 61 |
PTX administration decreased c-Fos expression within the hypothalamic paraventricular nucleus
(1 time)
|
Vascular Diseases
(1 time)
|
VEH (1 time)
|
2020 Systemic administration of pentoxifylline attenuates the development of hypertension in renovascular hypertensive rats.
|
| 62 |
PTX alone
(1 time)
|
Biochemistry
(1 time)
|
17-AAG (1 time)
RAP (1 time)
TRIO (1 time)
|
2017 Triolimus: A Multi-Drug Loaded Polymeric Micelle Containing Paclitaxel, 17-AAG, and Rapamycin as a Novel Radiosensitizer.
|
| 63 |
PTX arrangement, although globular shapes exist at f
(1 time)
|
Biochemistry
(1 time)
|
AA (1 time)
CG (1 time)
MD (1 time)
|
2010 Characterization of a clinical polymer-drug conjugate using multiscale modeling.
|
| 64 |
PTX group
(1 time)
|
Complementary Therapies
(1 time)
|
TSA (2 times)
MMP (1 time)
PARP (1 time)
|
2008 [Effects of trichostatin A and paclitaxel on apoptosis and microtubule stabilization in endometrial carcinoma cells: an in vitro research].
|
| 65 |
PTX IPCNs
(1 time)
|
Biomedical Engineering
(1 time)
|
IND (1 time)
IPCNs (1 time)
PEI (1 time)
|
2019 Computer-assisted engineering of programmed drug releasing multilayer nanomedicine via indomethacin-mediated ternary complex for therapy against a multidrug resistant tumor.
|
| 66 |
PTX loaded L-PD
(1 time)
|
Chemistry
(1 time)
|
---
|
2019 Reduction-Triggered Paclitaxel Release Nano-Hybrid System Based on Core-Crosslinked Polymer Dots with a pH-Responsive Shell-Cleavable Colorimetric Biosensor.
|
| 67 |
PTX+ sham NPX
(1 time)
|
Metabolism
(1 time)
|
CKD (1 time)
NPX (1 time)
Sham (1 time)
|
2008 Differential effects of intermittent PTH(1-34) and PTH(7-34) on bone microarchitecture and aortic calcification in experimental renal failure.
|
| 68 |
PTX, and Al-stained surface had decreased in all but one
(1 time)
|
Nephrology
(1 time)
|
Al (1 time)
|
1992 Pretransplant parathyroidectomy in renal failure: effects on bone histology and aluminum deposits during dialysis and after kidney transplantation.
|
| 69 |
PTX, and M
(1 time)
|
Molecular Biology
(1 time)
|
NIR (1 time)
TfR (1 time)
|
2012 Transferrin-conjugated micelles: enhanced accumulation and antitumor effect for transferrin-receptor-overexpressing cancer models.
|
| 70 |
PTX, M
(1 time)
|
Biomimetics
(1 time)
|
FA (1 time)
|
2015 Anti-tumor activity of folate targeted biodegradable polymer-paclitaxel conjugate micelles on EMT-6 breast cancer model.
|
| 71 |
PTX, resistant to paclitaxel
(1 time)
|
Neoplasms
(1 time)
|
---
|
2004 Antitumour and antiangiogenic effects of IDN 5390, a novel C-seco taxane, in a paclitaxel-resistant human ovarian tumour xenograft.
|
| 72 |
PTX-ADSCs
(1 time)
|
Pharmacological Phenomena
(1 time)
|
ADSCs (1 time)
CM (1 time)
OvCa (1 time)
|
2020 Adipose-Derived Stem Cells Primed with Paclitaxel Inhibit Ovarian Cancer Spheroid Growth and Overcome Paclitaxel Resistance.
|
| 73 |
PTX-MSC-EMs
(1 time)
|
Pharmacology
(1 time)
|
EMs (1 time)
MSCs (1 time)
NTA (1 time)
|
2018 A New Approach for Loading Anticancer Drugs Into Mesenchymal Stem Cell-Derived Exosome Mimetics for Cancer Therapy.
|
| 74 |
PTX-S-S-VE, the conjugation of paclitaxel
(1 time)
|
Natural Science Disciplines
(1 time)
|
VE (1 time)
|
2015 Programmed Hydrolysis in Designing Paclitaxel Prodrug for Nanocarrier Assembly.
|
| 75 |
PTX/PECTGel, assembled from paclitaxel
(1 time)
|
Biocompatible Materials
(1 time)
|
EAC (1 time)
NPs (1 time)
|
2013 A reconstituted "two into one" thermosensitive hydrogel system assembled by drug-loaded amphiphilic copolymer nanoparticles for the local delivery of paclitaxel.
|
| 76 |
PTX/PEOALAGel based on paclitaxel
(1 time)
|
Pharmacy
(1 time)
|
i.v (1 time)
NPs (1 time)
PEOALA (1 time)
|
2017 A reconstituted thermosensitive hydrogel system based on paclitaxel-loaded amphiphilic copolymer nanoparticles and antitumor efficacy.
|
| 77 |
PTX/TMZ-NPs
(1 time)
|
Neoplasms
(1 time)
|
NPs (1 time)
TMZ (1 time)
|
2016 The synergic antitumor effects of paclitaxel and temozolomide co-loaded in mPEG-PLGA nanoparticles on glioblastoma cells.
|
| 78 |
SOC-paclitaxel
(1 time)
|
Nanotechnology
(1 time)
|
DL (1 time)
SOC (1 time)
|
2016 Nanomedicine engulfed by macrophages for targeted tumor therapy.
|
| 79 |
TS-1+paclitaxel
(1 time)
|
Antineoplastic Agents
(1 time)
|
---
|
2006 [A case of long-term survival of gastric cancer with peritoneal metastasis effectively treated by TS-1 and paclitaxel (PTX) combination therapy].
|
| 80 |
UBX-parathyroidectomized
(1 time)
|
Endocrinology
(1 time)
|
---
|
1975 Effects of the ultimobranchial and parathyroid glands and vitamins D2, D3 and dihydrotachysterol2 on blood calcium and intestinal calcium transport in the frog.
|
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