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Abbreviation: ROCK
Appearance Frequency: 931 time(s)
Long forms: 40

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Long Form No. Long Form Research Area Co-occurring Abbreviation PubMed/MEDLINE Info. (Year, Title)
Rho-associated kinase
(858 times)
Cell Biology
(139 times)
MLC (43 times)
RhoA (27 times)
MLCK (23 times)
1999 Relaxation of contracted rabbit tracheal and human bronchial smooth muscle by Y-27632 through inhibition of Ca2+ sensitization.
Rho-associated protein serine/threonine kinase
(11 times)
Cell Biology
(3 times)
Cas (1 time)
CFL1 (1 time)
CsA (1 time)
2001 Y-27632, an inhibitor of Rho-associated kinases, prevents tyrosine phosphorylation of focal adhesion kinase and paxillin induced by bombesin: dissociation from tyrosine phosphorylation of p130(CAS).
Rho-associated coiled-coil forming protein serine/threonine kinase
(10 times)
Pharmacology
(4 times)
alpha-SMA (1 time)
BBB (1 time)
CE (1 time)
2000 Pharmacological properties of Y-27632, a specific inhibitor of rho-associated kinases.
role of the Rho/Rho-associated kinase
(7 times)
Molecular Biology
(2 times)
AJC (1 time)
CECs (1 time)
Cx43 (1 time)
2003 Implication of Rho-associated kinase in the elevation of extracellular dopamine levels and its related behaviors induced by methamphetamine in rats.
rotating cartesian k-space
(5 times)
Radiotherapy
(1 time)
bSSFP (1 time)
GTV (1 time)
MRgRT (1 time)
2017 Self-gated 4D multiphase, steady-state imaging with contrast enhancement (MUSIC) using rotating cartesian K-space (ROCK): Validation in children with congenital heart disease.
Rockefeller
(4 times)
Toxicology
(2 times)
AChE (1 time)
GST (1 time)
MFO (1 time)
2007 Age and body size influence male sperm capacity of the dengue vector Aedes aegypti (Diptera: Culicidae).
Research in Osteochondritis of the Knee
(2 times)
Orthopedics
(1 time)
OCD (2 times)
ICC (1 time)
MRI (1 time)
2014 Trochlear groove osteochondritis dissecans of the knee patellofemoral joint.
Rigidity Optimized Conformational Kinetics
(2 times)
Chemistry
(1 time)
AsnRS (1 time)
2004 Sampling protein conformations and pathways.
Rac1-Rho kinase
(1 time)
Neoplasms
(1 time)
ADF (1 time)
DADS (1 time)
LIMK (1 time)
2013 DADS downregulates the Rac1-ROCK1/PAK1-LIMK1-ADF/cofilin signaling pathway, inhibiting cell migration and invasion.
10  Random Oligonucleotide Construction Kit
(1 time)
Biotechnology
(1 time)
--- 2001 ROCK: a spreadsheet-based program for the generation and analysis of random oligonucleotide primers used in PCR.
11  rats, and measured contractility and expression of PKs/RhoA/Rho kinase
(1 time)
Medicine
(1 time)
eNOS (1 time)
L-NAME (1 time)
PK (1 time)
2016 Phosphodiesterase inhibitor KMUP-3 displays cardioprotection via protein kinase G and increases cardiac output via G-protein-coupled receptor agonist activity and Ca(2+) sensitization.
12  RBrcGMP or stimulation of Rho kinase
(1 time)
Biomedical Engineering
(1 time)
NO (1 time)
PEG (1 time)
PKG (1 time)
2014 The role of valvular endothelial cell paracrine signaling and matrix elasticity on valvular interstitial cell activation.
13  regulation of actin cytoskeleton organization by RhoA/Rho-kinase
(1 time)
Biological Transport
(1 time)
IEB (1 time)
IEC (1 time)
TJ (1 time)
2014 Connecting metabolism to intestinal barrier function: The role of leptin.
14  regulation of artery contraction, Rho kinase
(1 time)
Vascular Diseases
(1 time)
RMA (1 time)
SMA (1 time)
2012 Different effect of Rho kinase inhibition on calcium signaling in rat isolated large and small arteries.
15  regulation of execution events we focused on Rho kinase
(1 time)
Cell Biology
(1 time)
--- 2006 Rho kinase regulates phagocytosis, surface expression of GlcNAc, and Golgi fragmentation of apoptotic PC12 cells.
16  regulation of the dynamics of the actin cytoskeleton, Rho-kinase
(1 time)
Biochemistry
(1 time)
ARC (1 time)
2008 Adenosine-oligoarginine conjugate, a novel bisubstrate inhibitor, effectively dissociates the actin cytoskeleton.
17  relatively common vascular malformations, characterized by increased Rho kinase
(1 time)
Neuropharmacology
(1 time)
CCMs (1 time)
2016 B-Cell Depletion Reduces the Maturation of Cerebral Cavernous Malformations in Murine Models.
18  relevance of the Rho-kinase
(1 time)
Urology
(1 time)
EFS (1 time)
PKC (1 time)
2008 Synergistic effects in neuromuscular activation and calcium-sensitization in the bladder trigone.
19  remodelling via activation of Rho kinase
(1 time)
Microbiology
(1 time)
HF (1 time)
2010 TGF-b2 induction regulates invasiveness of Theileria-transformed leukocytes and disease susceptibility.
20  Research in Osteochondritis dissecans of the Knee
(1 time)
General Surgery
(1 time)
OCD (1 time)
2016 Research in Osteochondritis Dissecans of the Knee: 2016 Update.
21  Research on Calculus Kinetics
(1 time)
Urology
(1 time)
--- 2002 Abstracts of the Research on Calculus Kinetics (ROCK) Society Meeting. 9-10 February 2002, San Antonio, Texas, USA.
22  response of the cytoplasm is abrogated by specific Rho-kinase
(1 time)
Biophysics
(1 time)
HUVECs (1 time)
VEGF (1 time)
2006 Microrheology and ROCK signaling of human endothelial cells embedded in a 3D matrix.
23  result of an increased RhoA/Rho-kinase
(1 time)
Sexual Dysfunction, Physiological
(1 time)
cGMP (1 time)
hBCs (1 time)
OAB (1 time)
2009 Vardenafil modulates bladder contractility through cGMP-mediated inhibition of RhoA/Rho kinase signaling pathway in spontaneously hypertensive rats.
24  Rho activity, Rho kinase
(1 time)
Pulmonary Medicine
(1 time)
CCh (1 time)
SNAP (1 time)
2006 Regulation of airway smooth muscle RhoA/ROCK activities by cholinergic and bronchodilator stimuli.
25  Rho effector kinase
(1 time)
Pharmacology
(1 time)
NF-kappaBeta (1 time)
P-gp (1 time)
TNF-alpha (1 time)
2018 Colchicine Pharmacokinetics and Mechanism of Action.
26  Rho-associated coiled-coil containing serine/threonine protein kinase
(1 time)
Cell Biology
(1 time)
tTG (1 time)
2006 Cell surface transglutaminase promotes RhoA activation via integrin clustering and suppression of the Src-p190RhoGAP signaling pathway.
27  Rho-associated kinase inhibitor
(1 time)
Stem Cells
(1 time)
hESCs (1 time)
hiPSCs (1 time)
hPSCs (1 time)
2012 Synergistic effect of medium, matrix, and exogenous factors on the adhesion and growth of human pluripotent stem cells under defined, xeno-free conditions.
28  Rho-associated protein kinase/Rho-kinase
(1 time)
Biochemistry
(1 time)
--- 2014 Rho-kinase as a therapeutic target in vascular diseases: striking nitric oxide signaling.
29  Rho-effector Rho-kinase
(1 time)
Cell Biology
(1 time)
GAP (1 time)
2009 Myosin IXa regulates epithelial differentiation and its deficiency results in hydrocephalus.
30  RhoA and its associated kinase
(1 time)
Neurology
(1 time)
DRGN (1 time)
GC (1 time)
2016 Anti-glycan antibodies halt axon regeneration in a model of Guillain Barre Syndrome axonal neuropathy by inducing microtubule disorganization via RhoA-ROCK-dependent inactivation of CRMP-2.
31  RhoA and its effector Rho Kinase
(1 time)
Chemistry
(1 time)
OPCs (1 time)
2010 A central role for RhoA during oligodendroglial maturation in the switch from netrin-1-mediated chemorepulsion to process elaboration.
32  RhoA translocation and activity, Rho Kinase
(1 time)
Biochemistry
(1 time)
Hcy (1 time)
PS (1 time)
2011 Homocysteine induces phosphatidylserine exposure in cardiomyocytes through inhibition of Rho kinase and flippase activity.
33  Roche medicinal chemistry knowledge
(1 time)
Drug Therapy
(1 time)
--- 2011 ROCK: the Roche medicinal chemistry knowledge application - design, use and impact.
34  ROCK I and ROCK II
(1 time)
Pharmacology
(1 time)
--- 2003 Expression and functional role of Rho-kinase in rat urinary bladder smooth muscle.
35  rock.icr.ac.uk
(1 time)
Neoplasms
(1 time)
--- 2010 ROCK: a breast cancer functional genomics resource.
36  Rockefeller strain
(1 time)
Parasitology
(1 time)
MOYO (1 time)
1994 Reinterpretation of the genetics of susceptibility of Aedes aegypti to Plasmodium gallinaceum.
37  role of agonist-induced Rho kinase
(1 time)
Cell Biology
(1 time)
NHLF (1 time)
SPP (1 time)
TGF-beta1 (1 time)
2007 Diverse signaling pathways regulate fibroblast differentiation and transformation through Rho kinase activation.
38  role of H-ras and its implications in the RhoA/Rho kinase
(1 time)
Gastroenterology
(1 time)
IAS (1 time)
SMC (1 time)
2007 H-ras inhibits RhoA/ROCK leading to a decrease in the basal tone in the internal anal sphincter.
39  role of pharmacological inhibition of rho kinase
(1 time)
Brain
(1 time)
RGC (1 time)
2008 ROCK inhibition and CNTF interact on intrinsic signalling pathways and differentially regulate survival and regeneration in retinal ganglion cells.
40  up-regulation of the contractile RhoA/Rho-kinase
(1 time)
Sexual Dysfunction, Physiological
(1 time)
Bax (1 time)
Bcl-2 (1 time)
dUTP (1 time)
2011 Chronic treatment with an oral rho-kinase inhibitor restores erectile function by suppressing corporal apoptosis in diabetic rats.