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Abbreviation: SAICAR
Appearance Frequency: 57 time(s)
Long forms: 16

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Long Form No. Long Form Research Area Co-occurring Abbreviation PubMed/MEDLINE Info. (Year, Title)
succinylaminoimidazole carboxamide ribotide
(27 times)
Biochemistry
(9 times)
S-Ado (15 times)
ADSL (9 times)
AICAR (4 times)
1976 Biochemical genetics of Chinese hamster cell mutants with deviant purine metabolism. IV. Isolation of a mutant which accumulates adenylosuccinic acid and succinylaminoimidazole carboxamide ribotide.
5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide
(7 times)
Biochemistry
(4 times)
AIR (3 times)
AICAR (2 times)
ASL (2 times)
1980 Two complementary radiometric methods for the measurement of 5-amino-4-imidazole-N-succinocarboxamide ribonucleotide synthetase (SAICAR synthetase).
4-(N-succinocarboxamide)-5-aminoimidazole ribonucleotide
(4 times)
Biochemistry
(3 times)
CAIR (3 times)
AIR (2 times)
MFP (1 time)
1999 Evidence for the direct transfer of the carboxylate of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to generate 4-carboxy-5-aminoimidazole ribonucleotide catalyzed by Escherichia coli PurE, an N5-CAIR mutase.
5'-phosphoribosyl-4-succinocarboxamide-5-aminoimidazole
(3 times)
Molecular Biology
(2 times)
AICA riboside (1 time)
1986 Detection of 5'-phosphoribosyl-4-(N-succinylcarboxamide)-5-aminoimidazole in urine by use of the Bratton-Marshall reaction: identification of patients deficient in adenylosuccinate lyase activity.
succinyl-5-aminoimidazole-4-carboxamide-1-ribose-5'-phosphate
(3 times)
Cell Biology
(1 time)
PKM2 (2 times)
FBP (1 time)
2014 SAICAR induces protein kinase activity of PKM2 that is necessary for sustained proliferative signaling of cancer cells.
4-((N-succinylamino)carbonyl)-5-aminoimidazole ribonucleotide
(2 times)
Biochemistry
(2 times)
AIR (2 times)
NAIR (2 times)
CAIR (1 time)
1994 Carboxylases in de novo purine biosynthesis. Characterization of the Gallus gallus bifunctional enzyme.
phosphoribosylaminoimidazole-succinocarboxamide
(2 times)
Cell Biology
(1 time)
AICAR (1 time)
AIR (1 time)
Asp (1 time)
2015 Catalytic pathway, substrate binding and stability in SAICAR synthetase: A structure and molecular dynamics study.
N-succino-AICAR
(1 time)
Neoplasms
(1 time)
AICAR (1 time)
FAICAR (1 time)
OMP (1 time)
1989 Dual effects of pyrazofurin and 3-deazauridine upon pyrimidine and purine biosynthesis in mouse L1210 leukemia.
N-succinocarboxamide ribonucleotide 5'-phosphate
(1 time)
Biochemistry
(1 time)
AICAR (2 times)
2011 Physiological and toxic effects of purine intermediate 5-amino-4-imidazolecarboxamide ribonucleotide (AICAR) in yeast.
10  SAICA ribotide
(1 time)
Genetics, Medical
(1 time)
ADSL (1 time)
S-Ado (1 time)
SAICA (1 time)
2000 Clinical, biochemical and molecular genetic correlations in adenylosuccinate lyase deficiency.
11  some derivatives and analogues of N-(5-amino-1-beta-D-ribofuranosylimidazole-4-carbonyl)-L-aspartic acid 5'-phosphate
(1 time)
Chemistry
(1 time)
--- 1968 Purines, pyrimidines, and imidazoles. XXVII. The synthesis of some derivatives and analogues of N-(5-amino-1-beta-D-ribofuranosylimidazole-4-carbonyl)-L-aspartic acid 5'-phosphate (SAICAR) including a competitive enzyme (adenylosuccinate AMP-lyase no. 4.3.2.2.) inhibitor-N-(5-amino-1-beta-D-ribofuranosylimidazole-4-carbonyl)-L-threo-beta-methyl aspartic acid 5'-phosphate.
12  Specifically, adenylosuccinate synthetase and phosphoribosylaminoimidazole-succinocarboxamide
(1 time)
Medicine
(1 time)
--- 2017 Insight into cordycepin biosynthesis of Cordyceps militaris: Comparison between a liquid surface culture and a submerged culture through transcriptomic analysis.
13  substrates, 5-amino-4-imidazole-N-succinocarboxamide ribotide
(1 time)
Metabolism
(1 time)
ADSL (1 time)
S-Ado (1 time)
SAICAr (1 time)
2005 Preparation of 5-amino-4-imidazole-N-succinocarboxamide ribotide, 5-amino-4-imidazole-N-succinocarboxamide riboside and succinyladenosine, compounds usable in diagnosis and research of adenylosuccinate lyase deficiency.
14  succinyl-AICAR
(1 time)
Molecular Biology
(1 time)
--- 2009 Metabolic intermediates selectively stimulate transcription factor interaction and modulate phosphate and purine pathways.
15  synthesis of AMP: the conversion of phosphoribosylsuccinyl-aminoimidazole carboxamide
(1 time)
Biochemistry
(1 time)
ADSL (1 time)
WT (1 time)
2012 Structural and biochemical characterization of human adenylosuccinate lyase (ADSL) and the R303C ADSL deficiency-associated mutation.
16  synthetase and succinoaminoimidazole carboxamide ribonucleotide
(1 time)
Biochemistry
(1 time)
--- 1993 Two purine biosynthetic enzymes that are required for cadmium tolerance in Schizosaccharomyces pombe utilize cysteine sulfinate in vitro.