| 1 |
signal transducer and activator of transcription 3
(4082 times)
|
Neoplasms
(971 times)
|
IL-6 (415 times)
JAK2 (235 times)
IL (218 times)
|
1995 Activation of signal transducer and activator of transcription-3 (Stat3) expression by interferon-gamma and interleukin-6 in hepatoma cells.
|
| 2 |
signal transducer and activator 3
(13 times)
|
Neoplasms
(4 times)
|
IL-6 (3 times)
mRCC (2 times)
APR (1 time)
|
1998 Requirement for cooperative interaction of interleukin-6 responsive element type 2 and glucocorticoid responsive element in the synergistic activation of mouse metallothionein-I gene by interleukin-6 and glucocorticoid.
|
| 3 |
STAT3-C
(8 times)
|
Neoplasms
(3 times)
|
EMT (2 times)
ALA (1 time)
AS (1 time)
|
2006 Cyclin D1 is transcriptionally regulated by and required for transformation by activated signal transducer and activator of transcription 3.
|
| 4 |
STAT3 siRNA
(4 times)
|
Genetics, Medical
(1 time)
|
siRNA (2 times)
STAT1 (2 times)
CNTF (1 time)
|
2013 [Small interfering RNA targeting STAT3 enhances antitumor activity of doxorubicin].
|
| 5 |
STAT3KO
(3 times)
|
Cardiology
(2 times)
|
Cre (1 time)
CsA (1 time)
GFAP (1 time)
|
2008 STAT3 is a critical regulator of astrogliosis and scar formation after spinal cord injury.
|
| 6 |
signal transducer-activated transcript-3
(2 times)
|
Physiology
(1 time)
|
CHOP (1 time)
DIO (1 time)
ER (1 time)
|
2006 Role of hypothalamic Foxo1 in the regulation of food intake and energy homeostasis.
|
| 7 |
signal transduction and transcription-3
(2 times)
|
Neoplasms
(1 time)
|
BCL (1 time)
BL (1 time)
DLBCL (1 time)
|
2013 A new diagnostic algorithm for Burkitt and diffuse large B-cell lymphomas based on the expression of CSE1L and STAT3 and on MYC rearrangement predicts outcome.
|
| 8 |
signal and transducer of transcription 3
(1 time)
|
Molecular Biology
(1 time)
|
HIF (1 time)
VEGF (1 time)
|
2005 HIF-1alpha, STAT3, CBP/p300 and Ref-1/APE are components of a transcriptional complex that regulates Src-dependent hypoxia-induced expression of VEGF in pancreatic and prostate carcinomas.
|
| 9 |
siRNA-STAT3
(1 time)
|
|
siRNA-STAT1 (1 time)
|
2017 Acitretin modulates HaCaT cells proliferation through STAT1- and STAT3-dependent signaling.
|
| 10 |
STAT3 delta
(1 time)
|
Molecular Biology
(1 time)
|
CSF-1R (1 time)
|
1999 Regulation by Gi2 proteins of v-fms-induced proliferation and transformation via Src-kinase and STAT3.
|
| 11 |
STAT3 P-Tyr705
(1 time)
|
Pathology
(1 time)
|
IL-11 (1 time)
|
2001 Increased expression of the interleukin-11 receptor and evidence of STAT3 activation in prostate carcinoma.
|
| 12 |
STAT3 peptide
(1 time)
|
Cell Biology
(1 time)
|
IL-6 (1 time)
|
2013 Interleukin-6-induced satellite cell proliferation is regulated by induction of the JAK2/STAT3 signalling pathway through cyclin D1 targeting.
|
| 13 |
STAT3 ph
(1 time)
|
Occupational Medicine
(1 time)
|
JAK/STAT (1 time)
JAK2 (1 time)
MPL (1 time)
|
2016 Activation of Janus kinase/signal transducers and activators of transcription pathway involved in megakaryocyte proliferation induced by vanadium resembles some aspects of essential thrombocythemia.
|
| 14 |
STAT3 phosphorylated on Y705, pSTAT3
(1 time)
|
Neoplasms
(1 time)
|
NSCLC (1 time)
PL (1 time)
sh (1 time)
|
2015 Small-molecule targeting of signal transducer and activator of transcription (STAT) 3 to treat non-small cell lung cancer.
|
| 15 |
STAT3 Y705F
(1 time)
|
Neoplasms
(1 time)
|
JAK2 (1 time)
OPN (1 time)
STAT (1 time)
|
2010 Activation of JAK2/STAT3 signaling by osteopontin promotes tumor growth in human breast cancer cells.
|
| 16 |
STAT3-deficient mice
(1 time)
|
Gastroenterology
(1 time)
|
DSS (1 time)
IEC (1 time)
IL (1 time)
|
2013 Deletion of intestinal epithelial cell STAT3 promotes T-lymphocyte STAT3 activation and chronic colitis following acute dextran sodium sulfate injury in mice.
|
| 17 |
STAT3beta
(1 time)
|
Allergy and Immunology
(1 time)
|
ASM (1 time)
|
2009 Critical role for STAT3 in IL-17A-mediated CCL11 expression in human airway smooth muscle cells.
|
| 18 |
STAT3CA
(1 time)
|
Gastroenterology
(1 time)
|
BAR-T (1 time)
Ser727 (1 time)
Tyr705 (1 time)
|
2015 Mitochondrial STAT3 contributes to transformation of Barrett's epithelial cells that express oncogenic Ras in a p53-independent fashion.
|
| 19 |
STAT3DB
(1 time)
|
Molecular Biology
(1 time)
|
PDGFRalpha (1 time)
|
2006 Neoplastic transformation by the gep oncogene, Galpha12, involves signaling by STAT3.
|
| 20 |
STAT3wt
(1 time)
|
Hematology
(1 time)
|
CTCL (1 time)
MF (1 time)
STAT (1 time)
|
2004 In vivo activation of STAT3 in cutaneous T-cell lymphoma. Evidence for an antiapoptotic function of STAT3.
|
| 21 |
stress responsive transcription factor, transducer and activator of transcription 3
(1 time)
|
Cell Death
(1 time)
|
NF-kappaB (1 time)
PERK (1 time)
TNF-alpha (1 time)
|
2018 Modulation of nuclear factor-kappa B activation by the endoplasmic reticulum stress sensor PERK to mediate estrogen-induced apoptosis in breast cancer cells.
|
| 22 |
suggesting that nobiletin also acts through the CD36
(1 time)
|
Food
(1 time)
|
CD36 (1 time)
GAS (1 time)
NF-kappaB (1 time)
|
2018 Nobiletin Inhibits CD36-Dependent Tumor Angiogenesis, Migration, Invasion, and Sphere Formation Through the Cd36/Stat3/Nf-Kappab Signaling Axis.
|
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