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Abbreviation: THC
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Long Form No. Long Form Research Area Co-occurring Abbreviation PubMed/MEDLINE Info. (Year, Title)
delta-9-tetrahydrocannabinol
(1838 times)
Pharmacology
(497 times)
CBD (261 times)
CBN (74 times)
MS (35 times)
1969 A comparison of LSD-25 with (-)-delta-9-trans-tetrahydrocannabinol (THC) and attempted cross tolerance between LSD and THC.
total haemocyte count
(180 times)
Allergy and Immunology
(122 times)
SOD (66 times)
PO (65 times)
DHC (21 times)
2000 Responses of giant freshwater prawn (Macrobrachium rosenbergii) to challenge by two strains of Aeromonas spp.
tetrahydrocurcumin
(106 times)
Pharmacology
(25 times)
CUR (12 times)
DMC (6 times)
BDMC (5 times)
1982 Anti-inflammatory and irritant activities of curcumin analogues in rats.
total hydrocarbons
(43 times)
Environmental Health
(37 times)
CO (18 times)
PM (13 times)
NOx (9 times)
1992 Hydrocarbon exposures at petroleum bulk terminals and agencies.
total hemoglobin concentration
(29 times)
Biomedical Engineering
(8 times)
DOT (6 times)
DCS (5 times)
US (4 times)
2004 Spatial variations in optical and physiological properties of healthy breast tissue.
total hydrocarbon
(25 times)
Environmental Health
(23 times)
PM (6 times)
VOCs (5 times)
CO (4 times)
1999 Comparison of Analytical Techniques for Measuring Hydrocarbon Emissions from the Manufacture of Fiberglass-Reinforced Plastics.
total hydrocarbon content
(12 times)
Environmental Health
(6 times)
WAF (3 times)
BTEX (2 times)
CD (2 times)
2004 The ecotoxicology of vegetable versus mineral based lubricating oils: 3. Coral fertilization and adult corals.
9-delta-tetrahydocannabinol and cannabidiol
(10 times)
Neurology
(7 times)
MS (9 times)
NRS (2 times)
10MWT (1 time)
2005 Randomized, controlled trial of cannabis-based medicine in central pain in multiple sclerosis.
tensor hypercontraction
(9 times)
Chemistry
(9 times)
GPUs (2 times)
LS-THC (2 times)
AIMD (1 time)
2012 Communication: Tensor hypercontraction. III. Least-squares tensor hypercontraction for the determination of correlated wavefunctions.
10  tetrahydrochrysene
(9 times)
Endocrinology
(4 times)
ER (6 times)
MPP (2 times)
PR (2 times)
1999 Integrated "3+1" oxorhenium(V) complexes as estrogen mimics.
11  thermohaline circulation
(9 times)
Science
(5 times)
AMOC (1 time)
GCM (1 time)
GIN (1 time)
2002 Instability of glacial climate in a model of the ocean- atmosphere-cryosphere system.
12  telehomecare
(7 times)
Drug Therapy
(4 times)
CF (4 times)
COPD (1 time)
WTP (1 time)
2004 Telehomecare: a comparison of three Canadian models.
13  thulium-holmium-chromium:YAG
(7 times)
General Surgery
(7 times)
EHL (1 time)
ESWL (1 time)
UL (1 time)
1989 A fiberoptic compatible midinfrared laser with CO2 laser-like effect: application to atherosclerosis.
14  transhepatic cholangiography
(7 times)
Gastroenterology
(4 times)
CT (4 times)
ERCP (3 times)
ERC (2 times)
1979 Transhepatic cholangiography: the radiological method of choice in suspected obstructive jaundice.
15  Teaching Health Center
(6 times)
Primary Health Care
(4 times)
GME (2 times)
AMCs (1 time)
AY (1 time)
1993 [The teaching health centers of Barcelona. The opinions of residents].
16  total hospital charges
(6 times)
General Surgery
(3 times)
LOS (5 times)
NIS (3 times)
MEDPAR (2 times)
1998 A detailed analysis of charges for hematopoietic stem cell transplantation at a children's hospital.
17  transplantable hepatocellular carcinomas
(6 times)
Neoplasms
(4 times)
NHCP (2 times)
AFP (1 time)
BrdU (1 time)
1978 Comparison of transcription stimulating, phenol-soluble non-histone chromosomal proteins in normal rat liver and transplantable hepatocellular carcinomas.
18  3,4,5-trihydorxycinnamic acid
(5 times)
Cell Biology
(2 times)
LPS (4 times)
HO-1 (3 times)
ALI (1 time)
2012 3,4,5-Trihydroxycinnamic Acid Inhibits LPS-Induced iNOS Expression by Suppressing NF-kappaB Activation in BV2 Microglial Cells.
19  tall hair cells
(5 times)
Otolaryngology
(2 times)
SHC (3 times)
EIT (1 time)
HC (1 time)
1978 The ultrastructure of the basilar papilla of the chick.
20  tetrahydrocoptisine
(4 times)
Pharmacology
(4 times)
NF-kappaB (2 times)
NO (2 times)
THB (2 times)
1976 [Behavioral pharmacology of berberine-type alkaloids. (2) Central depressant effects of tetrahydroberberine (THB) and related compounds].
21  total hospital costs
(4 times)
General Surgery
(2 times)
LOS (2 times)
AH (1 time)
ICU LOS (1 time)
1992 Endoscopic laser therapy for obstructing and/or bleeding colorectal carcinoma.
22  (R,R)-5,11-diethyl-5,6,11,12-tetrahydro-2,8-chrysenediol
(3 times)
Drug Therapy
(1 time)
BPA (1 time)
DPN (1 time)
EPCs (1 time)
2011 Estrogen increases nitric-oxide production in human bronchial epithelium.
23  5,11-cis-diethyl-5,6,11,12-tetrahydrochrysene-2,8-diol
(3 times)
Molecular Biology
(2 times)
LBD (3 times)
ER (2 times)
8-PN (1 time)
2002 Structural characterization of a subtype-selective ligand reveals a novel mode of estrogen receptor antagonism.
24  T-helper cells
(3 times)
Allergy and Immunology
(2 times)
CTL (2 times)
IL-2 (2 times)
BBD (1 time)
1987 Frequency and functional characterization of specific T-helper cells infiltrating rat kidney allografts during acute rejection.
25  tertiary health care
(3 times)
Pharmaceutical Preparations
(2 times)
EDL (1 time)
FDCs (1 time)
INRUD (1 time)
2011 Comparison of three clinical environments for pre-clinical clinical skills training.
26  thiacloprid
(3 times)
Environmental Health
(2 times)
TWW (2 times)
DOC (1 time)
FEN (1 time)
2017 Laboratory persistence in soil of thiacloprid, pendimethalin and fenarimol incubated with treated wastewater and dissolved organic matter solutions. Contribution of soil biota.
27  thrombin-hirudin complex
(3 times)
Hematology
(3 times)
rH (2 times)
UH (2 times)
ATIII (1 time)
1994 Thrombin-Hirudin complex formation, thrombin-antithrombin III complex formation, and thrombin generation after intrinsic activation of plasma.
28  Tiaramide hydrochloride
(3 times)
Allergy and Immunology
(1 time)
BK (1 time)
1978 The anti-anaphylactic action of tiaramide hydrochloride.
29  trihexosylceramide
(3 times)
Biochemistry
(2 times)
DHC (2 times)
BMP (1 time)
DRM (1 time)
1988 [Isolation and identification of products of accumulation in Fabry disease].
30  2',4',6',4-tetrahydroxychalcone
(2 times)
Biomedical Engineering
(1 time)
CHS (1 time)
CTAL (1 time)
PHC (1 time)
2001 Enzymatic formation of aurones in the extracts of yellow snapdragon flowers.
31  5,6,11,12-tetrahydrochrysene
(2 times)
Biochemistry
(1 time)
ER (2 times)
RBA (1 time)
1992 Donor-acceptor tetrahydrochrysenes, inherently fluorescent, high-affinity ligands for the estrogen receptor: binding and fluorescence characteristics and fluorometric assay of receptor.
32  9-carboxy-11-nor-delta-9-tetrahydrocannabinol
(2 times)
Neurology
(2 times)
2-AG (1 time)
AANAT (1 time)
AEA (1 time)
2006 Cannabinoids attenuate norepinephrine-induced melatonin biosynthesis in the rat pineal gland by reducing arylalkylamine N-acetyltransferase activity without involvement of cannabinoid receptors.
33  cannabinoids--tetrahydrocannabinol
(2 times)
Chemistry, Clinical
(1 time)
CBD (1 time)
CBN (1 time)
CVs (1 time)
1990 Genetic effects of marijuana.
34  T hybridoma cells
(2 times)
Allergy and Immunology
(2 times)
AIDS (1 time)
RT (1 time)
1988 Processing by accessory cells for presentation to murine T cells of apamin, a disulfide-bonded 18 amino acid peptide.
35  Teen Health Clinics
(2 times)
Medical Informatics
(2 times)
ASA (2 times)
CPR (1 time)
CSMSA (1 time)
1995 A server architecture for ambulatory patient record systems.
36  Tele-HomeCare
(2 times)
Health Services
(2 times)
IOF (1 time)
QOL (1 time)
2006 Taking the call-bell home: a qualitative evaluation of Tele-HomeCare for children.
37  telehealthcare
(2 times)
Pulmonary Medicine
(2 times)
COPD (2 times)
AE (1 time)
CAT (1 time)
2016 Telehealthcare for Chronic Obstructive Pulmonary Disease in Switzerland Is Feasible and Appreciated by Patients.
38  temporary hemodialysis catheters
(2 times)
Kidney Transplantation
(1 time)
CRBI (1 time)
CRF (1 time)
CRS (1 time)
2007 Outcome and survival of temporary hemodialysis catheters: a prospective study from a single center in Iraq.
39  tetrahydrocortisol
(2 times)
Chemistry, Physical
(1 time)
11 beta-OHSD (1 time)
allo-THC (1 time)
apoA-I (1 time)
1991 Urinary steroid profiles and alcohol-related blood pressure elevation.
40  total extractable hydrocarbon content
(2 times)
Environmental Health
(1 time)
EC (1 time)
TOC (1 time)
TOM (1 time)
2006 Assessment and treatment of hydrocarbon inundated soils using inorganic nutrient (N-P-K) supplements: II. A case study of eneka oil spillage in Niger Delta, Nigeria.
41  total health care costs
(2 times)
Economics, Medical
(1 time)
ASCVD (1 time)
CV (1 time)
HRU (1 time)
2008 Health-related factors associated with the healthcare costs of office workers.
42  total heart calcification
(2 times)
Cardiology
(1 time)
ARC (1 time)
AVC (1 time)
CVD (1 time)
2013 Association between heart calcification assessed by echocardiography and future cardiovascular disease mortality and morbidity.
43  Total hemocytes
(2 times)
Biology
(2 times)
CAT (1 time)
CFU (1 time)
HH (1 time)
2004 Effects of hypercapnic hypoxia on the clearance of Vibrio campbellii in the Atlantic blue crab, Callinectes sapidus Rathbun.
44  Total Hospital Capacity
(2 times)
Disaster Medicine
(2 times)
AMB (1 time)
AMSI (1 time)
HACSC (1 time)
2012 Disaster metrics: quantification of acute medical disasters in trauma-related multiple casualty events through modeling of the Acute Medical Severity Index.
45  total number of hemocytes
(2 times)
Allergy and Immunology
(2 times)
CMS (1 time)
LPO (1 time)
PA (1 time)
2016 Ocean acidification weakens the immune response of blood clam through hampering the NF-kappa beta and toll-like receptor pathways.
46  total unburned hydrocarbon
(2 times)
Environmental Health
(2 times)
CO (2 times)
MGO (2 times)
BD (1 time)
2010 Experimental investigation of engine emissions with marine gas oil-oxygenate blends.
47  trans healthcare
(2 times)
Public Health
(1 time)
ITHCCH (2 times)
2017 [Quality development within interdisciplinary transgender healthcare : Results and implications of aparticipatory research project].
48  transient hypercapnia
(2 times)
Diagnostic Imaging
(2 times)
BOLD (1 time)
DeltaCBF (1 time)
FAIR (1 time)
2000 The effect of transient hypercapnia on task-related changes in cerebral blood flow and blood oxygenation in awake normal humans: a functional magnetic resonance imaging study.
49  Transient hypoxic contractions
(2 times)
Physiology
(1 time)
VSM (2 times)
SR (1 time)
1988 [Cellular mechanisms of hypoxic coronary spasm].
50  triple-headed gamma camera
(2 times)
Radiology
(1 time)
CNR (1 time)
DHC (1 time)
FWHMx,y (1 time)
1994 Myocardial [18F]FDG tomography using a conventional gamma camera and a seven pinhole collimator.
51  tunneled hemodialysis catheter
(2 times)
Nephrology
(1 time)
PB (1 time)
SBP (1 time)
2003 Utility of percutaneous intervention in the management of tunneled hemodialysis catheters.
52  typical hyperostosis cranii
(2 times)
Radiology
(1 time)
--- 1981 Computerized tomography in typical hyperostosis cranii (THC).
53  (3S)-1,2,3,4-tetrahydro-3-hydroxymethyl-beta-carboline-2- carbodithioate
(1 time)
Pharmacology
(1 time)
--- 1987 Effects of methyl (+) (3S)-1,2,3,4-tetrahydro-3-hydroxymethyl-beta-carboline-2- carbodithioate(THC), a new hepatoprotective agent, on protein synthesis and chronic liver injury induced by carbon tetrachroride in rats.
54  (INCREMENT)9-tetrahydrocannabinol
(1 time)
Behavioral Sciences
(1 time)
ICSS (1 time)
2016 Pharmacological modulation of neuropathic pain-related depression of behavior: effects of morphine, ketoprofen, bupropion and [INCREMENT]9-tetrahydrocannabinol on formalin-induced depression of intracranial self-stimulation in rats.
55  11-nor-9-carboxy-Delta9-tetrahydrocannabinol
(1 time)
Toxicology
(1 time)
MDMA (1 time)
2017 Evaluation of an Automated Reader and Color Interpretation-Based Immunoassays for Multiplexed Drug-of-Abuse Testing in Urine.
56  3,6,7-trihydroxycoumarin
(1 time)
Botany
(1 time)
--- 2003 Tissular localization of coumarins in the green alga Dasycladus vermicularis (Scopoli) Krasser: a photoprotective role?
57  4'-Tetrahydroxychalcone
(1 time)
Neoplasms
(1 time)
ISL (1 time)
2018 Suppression of lung cancer progression by isoliquiritigenin through its metabolite 2, 4, 2', 4'-Tetrahydroxychalcone.
58  9-THC
(1 time)
Endocrinology
(1 time)
--- 2004 On the application of cannabis in paediatrics and epileptology.
59  alpha-trihydroxy-5 beta-cholanoic acid
(1 time)
Biochemistry
(1 time)
G3 alpha 6oxo (1 time)
GCDC (1 time)
GHC (1 time)
1991 Ion-pair high-performance liquid chromatography of bile salt conjugates: application to pig bile.
60  around-the-clock oral synthetic Delta9-tetrahydrocannabinol
(1 time)
Toxicology
(1 time)
BP (1 time)
2013 Tolerance to effects of high-dose oral delta9-tetrahydrocannabinol and plasma cannabinoid concentrations in male daily cannabis smokers.
61  delta(Delta)9-tetrahydrocannabinol
(1 time)
Antineoplastic Agents
(1 time)
CINV (1 time)
PD (1 time)
PK (1 time)
2017 A review of oral cannabinoids and medical marijuana for the treatment of chemotherapy-induced nausea and vomiting: a focus on pharmacokinetic variability and pharmacodynamics.
62  Delta9-THC
(1 time)
Neuropharmacology
(1 time)
BDNF (1 time)
Delta9-THC (1 time)
miR (1 time)
2016 Delta9-Tetrahydrocannabinol (Delta9-THC) Promotes Neuroimmune-Modulatory MicroRNA Profile in Striatum of Simian Immunodeficiency Virus (SIV)-Infected Macaques.
63  T cell proliferation and gp120-specific IFNgamma production. ∆(9)-Tetrahydrocannabinol
(1 time)
Neuropharmacology
(1 time)
CB1 (1 time)
MHC-II (1 time)
WT (1 time)
2015 Modulation of HIVGP120 Antigen-Specific Immune Responses In Vivo by Delta9-Tetrahydrocannabinol.
64  T-cell hybridomas
(1 time)
Allergy and Immunology
(1 time)
BLCL (1 time)
EBV (1 time)
HCV (1 time)
2005 Recognition of endogenously synthesized HLA-DR4 restricted HCV epitopes presented by autologous EBV transformed B-lymphoblastoid cell line.
65  TACI highly conserved
(1 time)
Allergy and Immunology
(1 time)
CVID (1 time)
2012 Immunological characteristics and two novel mutations in TACI in a cohort of 28 pediatric patients with common variable immunodeficiency.
66  TACI highly conserved cytoplasmic domain
(1 time)
Allergy and Immunology
(1 time)
CSR (1 time)
TACI (1 time)
2013 Naturally occurring mutation affecting the MyD88-binding site of TNFRSF13B impairs triggering of class switch recombination.
67  Tambol Health Centers
(1 time)
Medicine
(1 time)
--- 2012 Core competencies to prevent and control chronic diseases of Tambol Health Centers' head in Thailand.
68  target heparin concentration
(1 time)
Anesthesiology
(1 time)
ACT (1 time)
CPB (1 time)
HDR (1 time)
1996 Age-related differences in heparin sensitivity and heparin-protamine interactions in cardiac surgery patients.
69  targets, ∆9-tetrahydrocannabinol
(1 time)
Natural Science Disciplines
(1 time)
--- 2015 Finding cannabinoids in hair does not prove cannabis consumption.
70  taurohyocholate
(1 time)
General Surgery
(1 time)
TC (1 time)
TDHC (1 time)
TLC (1 time)
1990 Taurohyocholate, taurocholate, and tauroursodeoxycholate but not tauroursocholate and taurodehydrocholate counteract effects of taurolithocholate in rat liver.
71  Teen Health Center
(1 time)
Health Services Research
(1 time)
CI (1 time)
HD (1 time)
HPV (1 time)
2018 Prevalence of potential sexual abuse in adolescents and young adults and feasibility of an assessment and management plan used in three research projects.
72  Tehran Hepatitis Center
(1 time)
Liver Diseases
(1 time)
TBTO (1 time)
2015 Efficacy and Tolerability of Peginterferon alpha-2a and Peginterferon alpha-2b in Iranian Patients With Chronic Hepatitis C.
73  Teklehaymanot Health Center
(1 time)
Biomedical Research
(1 time)
LFT (1 time)
RIs (1 time)
TASH (1 time)
2012 Robust reference intervals for liver function test (LFT) analytes in newborns and infants.
74  Tele-home care
(1 time)
Nursing
(1 time)
--- 2005 [The current status, feasibility and difficulties of tele-home care].
75  Tele-homecare technology
(1 time)
Health Services Research
(1 time)
COPD (1 time)
2013 Telehomecare technologies enhance self-management and empowerment among patients with chronic obstructive pulmonary disease (COPD) - where does health literacy fit into this equation?
76  telephonic health coaching
(1 time)
Rheumatology
(1 time)
FI (1 time)
TKR (1 time)
2018 Financial Incentives and Health Coaching to Improve Physical Activity Following Total Knee Replacement: A Randomized Controlled Trial.
77  telomeric heterochromatin
(1 time)
Molecular Biology
(1 time)
ActD (1 time)
CHD (1 time)
2005 [Dynamic binding of the telomeric human protein TRF1 to intrachromosomal blocks (TTAGGG)n in living Chinese hamster cells depends on transcription].
78  tentative human consensus
(1 time)
Science
(1 time)
ESTs (1 time)
1995 Initial assessment of human gene diversity and expression patterns based upon 83 million nucleotides of cDNA sequence.
79  Terazosin hydrochloride
(1 time)
Neoplasms
(1 time)
NSAID (1 time)
1999 Efficacy of selective alpha-1 blocker therapy in the treatment of acute urinary symptoms during radiotherapy for localized prostate cancer.
80  Tertiary Health Center
(1 time)
Environmental Health
(1 time)
CHC (1 time)
H-day (1 time)
SHC (1 time)
2016 The Impact of General Strike on Government Healthcare Delivery in Kerala State in India.
81  tested and optimised for routine analysis of hydrocarbons
(1 time)
Biology
(1 time)
PAH (1 time)
PCB (1 time)
SFE (1 time)
1999 Routine analysis of hydrocarbons, PCB and PAH in marine sediments using supercritical CO2 extraction
82  tested whether administration of ∆9-tetrahydrocannabinol
(1 time)
Pharmacology
(1 time)
AITC (1 time)
2018 Anti-migraine effect of ∆9-tetrahydrocannabinol in the female rat.
83  tetraheme cytochrome c subunit
(1 time)
Biochemistry
(1 time)
HiPIP (1 time)
HP (1 time)
RC (1 time)
2004 Electron transfer from HiPIP to the photooxidized tetraheme cytochrome subunit of Allochromatium vinosum reaction center: new insights from site-directed mutagenesis and computational studies.
84  tetrahydrocolumbamine
(1 time)
Botany
(1 time)
CjSMT (1 time)
2010 Metabolic diversification of benzylisoquinoline alkaloid biosynthesis through the introduction of a branch pathway in Eschscholzia californica.
85  tetrahydrozoline hydrochloride
(1 time)
Chemistry Techniques, Analytical
(1 time)
OFX (1 time)
PAC (1 time)
POP (1 time)
2002 Simultaneous determination of ofloxacin, tetrahydrozoline hydrochloride, and prednisolone acetate by high-performance liquid chromatography.
86  tetryl, cocaine, and tetrahydrocannabinol
(1 time)
Chemistry Techniques, Analytical
(1 time)
SDI (1 time)
2016 Direct Analysis of Nonvolatile Chemical Compounds on Surfaces Using a Hand-Held Mass Spectrometer with Synchronized Discharge Ionization Function.
87  Thai herbal compression
(1 time)
Biomedical Research
(1 time)
OA (1 time)
TM (1 time)
2014 Thai massage, and Thai herbal compress versus oral ibuprofen in symptomatic treatment of osteoarthritis of the knee: a randomized controlled trial.
88  thalamocortical
(1 time)
Neurology
(1 time)
BMI (1 time)
INC (1 time)
1995 Cortical synchronized activity evoked by thalamocortical stimulation in vitro.
89  than MDMA, especially marijuana
(1 time)
Psychopharmacology
(1 time)
--- 2006 Cognitive function and mood in MDMA/THC users, THC users and non-drug using controls.
90  Thana Health Complex
(1 time)
Medicine
(1 time)
--- 1995 Perception of indoor patients on the services of some Thana Health Complexes.
91  THC concentration, but no CBD
(1 time)
Cannabinoids
(1 time)
CBD (1 time)
2018 A Novel Observational Method for Assessing Acute Responses to Cannabis: Preliminary Validation Using Legal Market Strains.
92  THC-set
(1 time)
Drug Therapy
(1 time)
CBD (1 time)
2005 Randomized, double-blind, placebo-controlled study about the effects of cannabidiol (CBD) on the pharmacokinetics of Delta9-tetrahydrocannabinol (THC) after oral application of THC verses standardized cannabis extract.
93  THC-SLNs
(1 time)
Pharmacy
(1 time)
--- 2018 Topical delivery of tetrahydrocurcumin lipid nanoparticles effectively inhibits skin inflammation: in vitro and in vivo study.
94  THC-vs vehicle-exposed male
(1 time)
Endocrinology
(1 time)
--- 1995 Effects of prenatal exposure to delta-9-tetrahydrocannabinol on reproductive, endocrine and immune parameters of male and female rat offspring.
95  THCin utero exhibited an increased latency to mount
(1 time)
Endocrinology
(1 time)
--- 1995 Effects of prenatal exposure to delta-9-tetrahydrocannabinol on reproductive, endocrine and immune parameters of male and female rat offspring.
96  THCtot
(1 time)
Medicine
(1 time)
CBD (1 time)
2016 Medicinal Cannabis: In Vitro Validation of Vaporizers for the Smoke-Free Inhalation of Cannabis.
97  therapeutic benefits of Delta⁹-tetrahydrocannabinol
(1 time)
Pharmacology
(1 time)
--- 2013 Non-psychotropic analgesic drugs from the endocannabinoid system: "magic bullet" or "multiple-target" strategies?
98  therapies containing tetrahydrocannabinol
(1 time)
CBD (1 time)
2017 A selective review of medical cannabis in cancer pain management.
99  thermal hydrocarbonization
(1 time)
Nanotechnology
(1 time)
NO (1 time)
pSiNPs (1 time)
2014 Nitric oxide-releasing porous silicon nanoparticles.
100  thermal, hydrological, and chemical
(1 time)
Chemistry
(1 time)
--- 2009 Modeling acid-gas generation from boiling chloride brines.