| 1 |
Toll-like receptor 4
(7636 times)
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Allergy and Immunology
(1051 times)
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LPS (2217 times)
NF-kappaB (1029 times)
TNF-alpha (906 times)
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1998 Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene.
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| 2 |
Toll receptor 4
(9 times)
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Pharmacology
(2 times)
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IL-1beta (3 times)
LPS (2 times)
TNF-alpha (2 times)
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2007 Functional cell permeable motifs within medically relevant proteins.
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| 3 |
lipopolysaccharide-Toll-like receptor 4
(3 times)
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Biochemistry
(1 time)
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CDAA (2 times)
NASH (2 times)
Ac-HSCs (1 time)
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2007 Autophosphorylation docking site Tyr-867 in Mer receptor tyrosine kinase allows for dissociation of multiple signaling pathways for phagocytosis of apoptotic cells and down-modulation of lipopolysaccharide-inducible NF-kappaB transcriptional activation.
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| 4 |
TLR4-KO
(3 times)
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Psychophysiology
(2 times)
|
WT (2 times)
CIH (1 time)
CPP (1 time)
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2015 Involvement of TLR4 in the long-term epigenetic changes, rewarding and anxiety effects induced by intermittent ethanol treatment in adolescence.
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| 5 |
Toll-4 receptor
(3 times)
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Physiology
(1 time)
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TNF-alpha (2 times)
AST (1 time)
CLP (1 time)
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2005 Failure of neutrophil migration toward infectious focus in severe sepsis: a critical event for the outcome of this syndrome.
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| 6 |
HMGB-1-toll-like receptor 4
(1 time)
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Neoplasms
(1 time)
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CIPN (1 time)
DRG (1 time)
HMGB1 (1 time)
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2019 High mobility group box-1-toll-like receptor 4-phosphatidylinositol 3-kinase/protein kinase B-mediated generation of matrix metalloproteinase-9 in the dorsal root ganglion promotes chemotherapy-induced peripheral neuropathy.
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| 7 |
tissues istoll-like receptor 4
(1 time)
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Neurology
(1 time)
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---
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2018 TLR4 inhibitor TAK-242 attenuates the adverse neural effects of diet-induced obesity.
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| 8 |
TLR4 deficiency
(1 time)
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Natural Science Disciplines
(1 time)
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ROS (1 time)
TLR (1 time)
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2017 Toll-like Receptor 4 Deficiency Reduces Oxidative Stress and Macrophage Mediated Inflammation in Hypertensive Kidney.
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| 9 |
TLR4 dimerization
(1 time)
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Allergy and Immunology
(1 time)
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ER (1 time)
LPS (1 time)
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2009 Chaperones and transport proteins regulate TLR4 trafficking and activation.
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| 10 |
TLR4 gene
(1 time)
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Veterinary Medicine
(1 time)
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HF J (1 time)
NZ (1 time)
PCR-SSCP (1 time)
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2017 Variation in the Toll-like Receptor 4 (TLR4) gene affects milk traits in dairy cows.
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| 11 |
TLR4 knockout
(1 time)
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General Surgery
(1 time)
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TLRs (1 time)
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2017 Enhanced Calvarial Bone Healing in CD11c-TLR4-/- and MyD88-/- Mice.
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| 12 |
TLR4 PF4
(1 time)
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Biochemistry
(1 time)
|
FAL (1 time)
IL-1beta (1 time)
NLRP3 (1 time)
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2018 TLR4-dependent upregulation of the platelet NLRP3 inflammasome promotes platelet aggregation in a murine model of hindlimb ischemia.
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| 13 |
TLR4 siRNA-treated and celastrol-treated group
(1 time)
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Complementary Therapies
(1 time)
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ANOVA (1 time)
FFAs (1 time)
IL (1 time)
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2018 [Influence of celastrol on toll-like receptor 4-mediated signaling pathway in the free fatty acids-induced HepG2 cells].
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| 14 |
TLR4 WT
(1 time)
|
Psychophysiology
(1 time)
|
CIH (1 time)
NA (1 time)
OSA (1 time)
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2018 Toll-like receptor-4 deficiency alleviates chronic intermittent hypoxia-induced renal injury, inflammation, and fibrosis.
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| 15 |
TLR4-A1
(1 time)
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Pain
(1 time)
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ATF (1 time)
DAMPs (1 time)
DRG (1 time)
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2021 TLR4 Antagonism Reduces Movement-Induced Nociception and ATF-3 Expression in Experimental Osteoarthritis.
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| 16 |
TLR4-defective mice
(1 time)
|
Allergy and Immunology
(1 time)
|
LPS (1 time)
MALDI TOF (1 time)
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2011 A deep rough type structure in Bordetella bronchiseptica lipopolysaccharide modulates host immune responses.
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| 17 |
Tlr4a and Tlr4b
(1 time)
|
Allergy and Immunology
(1 time)
|
MD (1 time)
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2016 Identification of Evolutionarily Conserved Md1 Splice Variants That Regulate Innate Immunity through Differential Induction of NF-кB.
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| 18 |
TLR4ca
(1 time)
|
Cardiology
(1 time)
|
HEK (1 time)
LPS (1 time)
PTX (1 time)
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2004 Toll-like receptor 4 coupled GI protein signaling pathways regulate extracellular signal-regulated kinase phosphorylation and AP-1 activation independent of NFkappaB activation.
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| 19 |
TLRs 4 and 3 was reduced in both PBC
(1 time)
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Gastroenterology
(1 time)
|
CHC (1 time)
PBC (1 time)
PMC (1 time)
|
2012 Hepatic expression of toll-like receptors 3, 4, and 9 in primary biliary cirrhosis and chronic hepatitis C.
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| 20 |
toll like report 4
(1 time)
|
Endocrinology
(1 time)
|
DKD (1 time)
Egr-1 (1 time)
mTOR (1 time)
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2018 Klotho Restraining Egr1/TLR4/mTOR Axis to Reducing the Expression of Fibrosis and Inflammatory Cytokines in High Glucose Cultured Rat Mesangial Cells.
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| 21 |
toll, such as receptor 4
(1 time)
|
Complementary Therapies
(1 time)
|
HSP70 (1 time)
IOD (1 time)
LDH (1 time)
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2011 Salvianolic acid B inhibits the TLR4-NFkappaB-TNFalpha pathway and attenuates neonatal rat cardiomyocyte injury induced by lipopolysaccharide.
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| 22 |
toll-like family of receptor 4
(1 time)
|
Medicine
(1 time)
|
HMGB1 (1 time)
HSCs (1 time)
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2013 High mobility group box-1 promotes the proliferation and migration of hepatic stellate cells via TLR4-dependent signal pathways of PI3K/Akt and JNK.
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| 23 |
Toll-like receptor 4 activation
(1 time)
|
Cell Biology
(1 time)
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HSMC (1 time)
LPS (1 time)
ROS (1 time)
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2010 Exposure of Toll-like receptors 4 to bacterial lipopolysaccharide (LPS) impairs human colonic smooth muscle cell function.
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| 24 |
Toll-like receptor 4 gene of humans
(1 time)
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Genetics
(1 time)
|
LPSs (1 time)
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2000 Phylogenetic variation and polymorphism at the toll-like receptor 4 locus (TLR4).
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| 25 |
toll-like receptor 4 gene product
(1 time)
|
Vascular Diseases
(1 time)
|
---
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2006 The lack of association between four point mutations in the promoter region of the toll-like 4 receptor gene and myocardial infarction.
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| 26 |
toll-like receptor 4 knockout mice
(1 time)
|
General Surgery
(1 time)
|
---
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2017 TLR4 Inactivation in Myeloid Cells Accelerates Bone Healing of a Calvarial Defect Model in Mice.
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| 27 |
Toll-like receptor 4 protein
(1 time)
|
Gastroenterology
(1 time)
|
FC (1 time)
HC (1 time)
HF (1 time)
|
2013 Free cholesterol accumulation in hepatic stellate cells: mechanism of liver fibrosis aggravation in nonalcoholic steatohepatitis in mice.
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| 28 |
toll-like receptor 4 signaling pathway
(1 time)
|
Medicine
(1 time)
|
DN (1 time)
MT (1 time)
TGF-beta1 (1 time)
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2020 Melatonin ameliorates hyperglycaemia-induced renal inflammation by inhibiting the activation of TLR4 and TGF-beta1/Smad3 signalling pathway.
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| 29 |
Toll-like receptor 4-mediated
(1 time)
|
Biology
(1 time)
|
AMPK (1 time)
H-Fx (1 time)
NAFLD (1 time)
|
2022 Fucoxanthin Attenuates Free Fatty Acid-Induced Nonalcoholic Fatty Liver Disease by Regulating Lipid Metabolism/Oxidative Stress/Inflammation via the AMPK/Nrf2/TLR4 Signaling Pathway.
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| 30 |
toll-like receptor 4-related protein
(1 time)
|
Biochemistry
(1 time)
|
MAPK (1 time)
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2019 Effect of oleic acid on induction of steatosis and cytotoxicity in BRL 3A cells.
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