1 |
Toll-like receptor 4
(7636 times)
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Allergy and Immunology (1051 times)
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LPS (2217 times) NF-kappaB (1029 times) TNF-alpha (906 times)
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1998 Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene.
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2 |
Toll receptor 4
(9 times)
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Pharmacology (2 times)
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IL-1beta (3 times) LPS (2 times) TNF-alpha (2 times)
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2007 Functional cell permeable motifs within medically relevant proteins.
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3 |
lipopolysaccharide-Toll-like receptor 4
(3 times)
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Biochemistry (1 time)
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CDAA (2 times) NASH (2 times) Ac-HSCs (1 time)
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2007 Autophosphorylation docking site Tyr-867 in Mer receptor tyrosine kinase allows for dissociation of multiple signaling pathways for phagocytosis of apoptotic cells and down-modulation of lipopolysaccharide-inducible NF-kappaB transcriptional activation.
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4 |
TLR4-KO
(3 times)
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Psychophysiology (2 times)
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WT (2 times) CIH (1 time) CPP (1 time)
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2015 Involvement of TLR4 in the long-term epigenetic changes, rewarding and anxiety effects induced by intermittent ethanol treatment in adolescence.
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5 |
Toll-4 receptor
(3 times)
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Physiology (1 time)
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TNF-alpha (2 times) AST (1 time) CLP (1 time)
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2005 Failure of neutrophil migration toward infectious focus in severe sepsis: a critical event for the outcome of this syndrome.
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6 |
HMGB-1-toll-like receptor 4
(1 time)
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Neoplasms (1 time)
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CIPN (1 time) DRG (1 time) HMGB1 (1 time)
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2019 High mobility group box-1-toll-like receptor 4-phosphatidylinositol 3-kinase/protein kinase B-mediated generation of matrix metalloproteinase-9 in the dorsal root ganglion promotes chemotherapy-induced peripheral neuropathy.
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7 |
tissues istoll-like receptor 4
(1 time)
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Neurology (1 time)
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2018 TLR4 inhibitor TAK-242 attenuates the adverse neural effects of diet-induced obesity.
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8 |
TLR4 deficiency
(1 time)
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Natural Science Disciplines (1 time)
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ROS (1 time) TLR (1 time)
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2017 Toll-like Receptor 4 Deficiency Reduces Oxidative Stress and Macrophage Mediated Inflammation in Hypertensive Kidney.
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9 |
TLR4 dimerization
(1 time)
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Allergy and Immunology (1 time)
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ER (1 time) LPS (1 time)
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2009 Chaperones and transport proteins regulate TLR4 trafficking and activation.
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10 |
TLR4 gene
(1 time)
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Veterinary Medicine (1 time)
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HF J (1 time) NZ (1 time) PCR-SSCP (1 time)
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2017 Variation in the Toll-like Receptor 4 (TLR4) gene affects milk traits in dairy cows.
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11 |
TLR4 knockout
(1 time)
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General Surgery (1 time)
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TLRs (1 time)
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2017 Enhanced Calvarial Bone Healing in CD11c-TLR4-/- and MyD88-/- Mice.
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12 |
TLR4 PF4
(1 time)
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Biochemistry (1 time)
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FAL (1 time) IL-1beta (1 time) NLRP3 (1 time)
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2018 TLR4-dependent upregulation of the platelet NLRP3 inflammasome promotes platelet aggregation in a murine model of hindlimb ischemia.
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13 |
TLR4 siRNA-treated and celastrol-treated group
(1 time)
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Complementary Therapies (1 time)
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ANOVA (1 time) FFAs (1 time) IL (1 time)
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2018 [Influence of celastrol on toll-like receptor 4-mediated signaling pathway in the free fatty acids-induced HepG2 cells].
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14 |
TLR4 WT
(1 time)
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Psychophysiology (1 time)
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CIH (1 time) NA (1 time) OSA (1 time)
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2018 Toll-like receptor-4 deficiency alleviates chronic intermittent hypoxia-induced renal injury, inflammation, and fibrosis.
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15 |
TLR4-A1
(1 time)
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Pain (1 time)
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ATF (1 time) DAMPs (1 time) DRG (1 time)
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2021 TLR4 Antagonism Reduces Movement-Induced Nociception and ATF-3 Expression in Experimental Osteoarthritis.
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16 |
TLR4-defective mice
(1 time)
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Allergy and Immunology (1 time)
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LPS (1 time) MALDI TOF (1 time)
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2011 A deep rough type structure in Bordetella bronchiseptica lipopolysaccharide modulates host immune responses.
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17 |
Tlr4a and Tlr4b
(1 time)
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Allergy and Immunology (1 time)
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MD (1 time)
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2016 Identification of Evolutionarily Conserved Md1 Splice Variants That Regulate Innate Immunity through Differential Induction of NF-кB.
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18 |
TLR4ca
(1 time)
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Cardiology (1 time)
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HEK (1 time) LPS (1 time) PTX (1 time)
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2004 Toll-like receptor 4 coupled GI protein signaling pathways regulate extracellular signal-regulated kinase phosphorylation and AP-1 activation independent of NFkappaB activation.
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19 |
TLRs 4 and 3 was reduced in both PBC
(1 time)
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Gastroenterology (1 time)
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CHC (1 time) PBC (1 time) PMC (1 time)
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2012 Hepatic expression of toll-like receptors 3, 4, and 9 in primary biliary cirrhosis and chronic hepatitis C.
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20 |
toll like report 4
(1 time)
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Endocrinology (1 time)
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DKD (1 time) Egr-1 (1 time) mTOR (1 time)
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2018 Klotho Restraining Egr1/TLR4/mTOR Axis to Reducing the Expression of Fibrosis and Inflammatory Cytokines in High Glucose Cultured Rat Mesangial Cells.
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21 |
toll, such as receptor 4
(1 time)
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Complementary Therapies (1 time)
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HSP70 (1 time) IOD (1 time) LDH (1 time)
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2011 Salvianolic acid B inhibits the TLR4-NFkappaB-TNFalpha pathway and attenuates neonatal rat cardiomyocyte injury induced by lipopolysaccharide.
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22 |
toll-like family of receptor 4
(1 time)
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Medicine (1 time)
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HMGB1 (1 time) HSCs (1 time)
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2013 High mobility group box-1 promotes the proliferation and migration of hepatic stellate cells via TLR4-dependent signal pathways of PI3K/Akt and JNK.
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23 |
Toll-like receptor 4 activation
(1 time)
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Cell Biology (1 time)
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HSMC (1 time) LPS (1 time) ROS (1 time)
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2010 Exposure of Toll-like receptors 4 to bacterial lipopolysaccharide (LPS) impairs human colonic smooth muscle cell function.
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24 |
Toll-like receptor 4 gene of humans
(1 time)
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Genetics (1 time)
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LPSs (1 time)
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2000 Phylogenetic variation and polymorphism at the toll-like receptor 4 locus (TLR4).
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25 |
toll-like receptor 4 gene product
(1 time)
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Vascular Diseases (1 time)
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2006 The lack of association between four point mutations in the promoter region of the toll-like 4 receptor gene and myocardial infarction.
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26 |
toll-like receptor 4 knockout mice
(1 time)
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General Surgery (1 time)
|
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2017 TLR4 Inactivation in Myeloid Cells Accelerates Bone Healing of a Calvarial Defect Model in Mice.
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27 |
Toll-like receptor 4 protein
(1 time)
|
Gastroenterology (1 time)
|
FC (1 time) HC (1 time) HF (1 time)
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2013 Free cholesterol accumulation in hepatic stellate cells: mechanism of liver fibrosis aggravation in nonalcoholic steatohepatitis in mice.
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28 |
toll-like receptor 4 signaling pathway
(1 time)
|
Medicine (1 time)
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DN (1 time) MT (1 time) TGF-beta1 (1 time)
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2020 Melatonin ameliorates hyperglycaemia-induced renal inflammation by inhibiting the activation of TLR4 and TGF-beta1/Smad3 signalling pathway.
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29 |
Toll-like receptor 4-mediated
(1 time)
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Biology (1 time)
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AMPK (1 time) H-Fx (1 time) NAFLD (1 time)
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2022 Fucoxanthin Attenuates Free Fatty Acid-Induced Nonalcoholic Fatty Liver Disease by Regulating Lipid Metabolism/Oxidative Stress/Inflammation via the AMPK/Nrf2/TLR4 Signaling Pathway.
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30 |
toll-like receptor 4-related protein
(1 time)
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Biochemistry (1 time)
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MAPK (1 time)
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2019 Effect of oleic acid on induction of steatosis and cytotoxicity in BRL 3A cells.
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