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■ Search Result - Abbreviation : hPXR

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Abbreviation: hPXR
Appearance Frequency: 145 time(s)
Long forms: 8

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Long Form No. Long Form Research Area Co-occurring Abbreviation PubMed/MEDLINE Info. (Year, Title)
human pregnane X receptor
(91 times)
Pharmacology
(39 times)
CYP3A4 (17 times)
hCAR (9 times)
LBD (5 times)
1999 The orphan human pregnane X receptor mediates the transcriptional activation of CYP3A4 by rifampicin through a distal enhancer module.
human PXR
(42 times)
Pharmacology
(25 times)
PXR (39 times)
CAR (6 times)
hCAR (6 times)
2002 Insights from a three-dimensional model into ligand binding to constitutive active receptor.
PXR-humanized
(7 times)
Pharmacology
(6 times)
PXR (7 times)
HFD (2 times)
WT (2 times)
2007 Rifaximin is a gut-specific human pregnane X receptor activator.
h of treatment because pregnane X receptor
(1 time)
Pharmacology
(1 time)
CCM (1 time)
2001 Calcium channel modulators of the dihydropyridine family are human pregnane X receptor activators and inducers of CYP3A, CYP2B, and CYP2C in human hepatocytes.
human and mice, a PXR-humanized mouse
(1 time)
Biochemistry
(1 time)
BAC (1 time)
hCYP3A4 (1 time)
PAC (1 time)
2007 CYP3A4 and pregnane X receptor humanized mice.
human nuclear pregnane X receptor
(1 time)
Science
(1 time)
--- 2001 The human nuclear xenobiotic receptor PXR: structural determinants of directed promiscuity.
human transcription factor pregnane X receptor
(1 time)
Chemistry
(1 time)
CYP3A4 (1 time)
2006 Evaluation of 170 xenobiotics as transactivators of human pregnane X receptor (hPXR) and correlation to known CYP3A4 drug interactions.
humanized PXR
(1 time)
Pharmacology
(1 time)
NP (1 time)
PXR (1 time)
WT (1 time)
2011 Nonylphenol-mediated CYP induction is PXR-dependent: The use of humanized mice and human hepatocytes suggests that hPXR is less sensitive than mouse PXR to nonylphenol treatment.