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Abbreviation: iPLA2
Appearance Frequency: 120 time(s)
Long forms: 29

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Long Form No. Long Form Research Area Co-occurring Abbreviation PubMed/MEDLINE Info. (Year, Title)
calcium-independent phospholipase A2
(59 times)
Biochemistry
(22 times)
BEL (10 times)
cPLA2 (9 times)
DHA (7 times)
1997 A novel cytosolic calcium-independent phospholipase A2 contains eight ankyrin motifs.
calcium-independent PLA2
(17 times)
Biochemistry
(6 times)
PLA2 (14 times)
cPLA2 (7 times)
BEL (4 times)
1998 Activation by P2X7 agonists of two phospholipases A2 (PLA2) in ductal cells of rat submandibular gland. Coupling of the calcium-independent PLA2 with kallikrein secretion.
independent phospholipase A2
(7 times)
Antioxidants
(1 time)
BEL (2 times)
COX-2 (2 times)
AD (1 time)
2001 Interleukin-1beta induced cyclooxygenase 2 expression and prostaglandin E2 secretion by human neuroblastoma cells: implications for Alzheimer's disease.
involved Ca(2+)-independent phospholipase A(2)
(5 times)
Biochemistry
(4 times)
BEL (2 times)
PKC (2 times)
AA (1 time)
1998 Inhibition of Ca2+-independent phospholipase A2 by bromoenol lactone attenuates prostaglandin generation induced by interleukin-1 beta and dibutyryl cAMP in rat mesangial cells.
independent PLA2
(4 times)
Drug Therapy
(1 time)
PLA2 (3 times)
cPLA2 (2 times)
sPLA2 (2 times)
2001 Stimulation of protease activated receptors on RT4 cells mediates arachidonic acid release via Ca2+ independent phospholipase A2.
inhibitor for the Ca2+-independent phospholipase A2
(3 times)
Neurology
(1 time)
BEL (2 times)
4-HHE (1 time)
4-HNE (1 time)
2002 Roles of various phospholipases A2 in providing lysophospholipid acceptors for fatty acid phospholipid incorporation and remodelling.
increased membrane-associated, Ca(2+)-independent phospholipase A2
(2 times)
Physiology
(1 time)
HCAECs (1 time)
PAF (1 time)
PAF-AH (1 time)
2002 Regulation of membrane-associated iPLA2 activity by a novel PKC isoform in ventricular myocytes.
intracellular PLA2
(2 times)
Neurology
(1 time)
PLA2 (2 times)
AA (1 time)
aiPLA2 (1 time)
1999 85 kDa cytosolic phospholipase A2 is a target for chronic lithium in rat brain.
calcium-independent cellular PLA2
(1 time)
Pathology
(1 time)
cPLA2 (1 time)
PLA2 (1 time)
sPLA2 (1 time)
2017 Specific inhibition of Xenorhabdus hominickii, an entomopathogenic bacterium, against different types of host insect phospholipase A2.
10  importantly, the application of a specific PRDX6 phospholipase A2
(1 time)
Pharmacology
(1 time)
PRDX6 (1 time)
2019 Identification of PRDX6 as a regulator of ferroptosis.
11  increased expression of via phospholipase A2
(1 time)
Cell Biology
(1 time)
LPS (1 time)
2011 Proinflammatory treatment of astrocytes with lipopolysaccharide results in augmented Ca2+ signaling through increased expression of via phospholipase A2 (iPLA2).
12  ineffective, the Ca(2+)-independent phospholipase A2
(1 time)
Biochemistry
(1 time)
BEL (1 time)
LPA (1 time)
1999 Ca(2+)-independent phospholipase A2 is required for alpha2-adrenergic-induced preadipocyte spreading.
13  inhibition of Ca2+-independent PLA2
(1 time)
Biochemistry
(1 time)
BEL (1 time)
PAP (1 time)
PLA2 (1 time)
1996 Bromoenol lactone inhibits magnesium-dependent phosphatidate phosphohydrolase and blocks triacylglycerol biosynthesis in mouse P388D1 macrophages.
14  inhibition of caspase-3/cytosolic Ca2+-independent phospholipase A2
(1 time)
Physiology
(1 time)
EMT (1 time)
NF-kappaB (1 time)
TNBC (1 time)
2017 Garcinol sensitizes breast cancer cells to Taxol through the suppression of caspase-3/iPLA2 and NF-kappaB/Twist1 signaling pathways in a mouse 4T1 breast tumor model.
15  inhibition, suggesting the participation of a Ca2+-independent PLA2
(1 time)
Biochemistry
(1 time)
AA (1 time)
DHA (1 time)
1998 Protein kinase C inhibitors stimulate arachidonic and docosahexaenoic acids release from uterine stromal cells through a Ca2+-independent pathway.
16  inhibitor of a beta-cell phospholipase A2
(1 time)
Endocrinology
(1 time)
BEL (1 time)
1998 Mass spectrometric evidence that agents that cause loss of Ca2+ from intracellular compartments induce hydrolysis of arachidonic acid from pancreatic islet membrane phospholipids by a mechanism that does not require a rise in cytosolic Ca2+ concentration.
17  inhibitor of cPLA2 and the Ca(+2)-independent phospholipase A2
(1 time)
Hematology
(1 time)
AA (1 time)
BEL (1 time)
cPLA2 (1 time)
1999 Phospholipase A2 enzymes regulate alpha IIb beta3-mediated, but not Fc gammaRII receptor-mediated, pp125FAK phosphorylation in platelets.
18  inhibitor of cytosolic PLA2 and Ca2+ -independent PLA2
(1 time)
Toxicology
(1 time)
ATK (1 time)
PAF (1 time)
PKC (1 time)
2004 Signalling pathways regulating human neutrophil migration induced by secretory phospholipases A2.
19  inhibitor of the Ca2+-independent PLA2 isoform
(1 time)
Biochemistry
(1 time)
BEL (1 time)
PCB (1 time)
PLA2 (1 time)
2001 Participation of Ca2+/calmodulin during activation of rat neutrophils by polychlorinated biphenyls.
20  inhibits the Ca(2+)-independent cytosolic phospholipase A2
(1 time)
Biochemistry
(1 time)
cPLA2 (1 time)
MAFP (1 time)
1996 Irreversible inhibition of Ca(2+)-independent phospholipase A2 by methyl arachidonyl fluorophosphonate.
21  intestinal phospholipase A2
(1 time)
Medicine
(1 time)
--- 1995 Bactericidal properties of murine intestinal phospholipase A2.
22  intracellular phospholipase A2
(1 time)
Biochemistry
(1 time)
COX-2 (1 time)
HGF (1 time)
NF (1 time)
2012 Interruption of hepatocyte growth factor signaling augmented oridonin-induced death in human non-small cell lung cancer A549 cells via c-met-nuclear factor-kappaB-cyclooxygenase-2 and c-Met-Bcl-2-caspase-3 pathways.
23  investigate whether group VIA Ca2+-independent PLA2
(1 time)
Biochemistry
(1 time)
PLA2 (1 time)
ROS (1 time)
STS (1 time)
2006 Calcium-independent phospholipase A2 localizes in and protects mitochondria during apoptotic induction by staurosporine.
24  investigated the role of Ca2+-independent phospholipase A2
(1 time)
Pharmacology
(1 time)
cPLA2 (1 time)
HIF-1 (1 time)
MAFP (1 time)
2006 Involvement of Ca2+-independent phospholipase A2 in the translocation of hypoxia-inducible factor-1alpha to the nucleus under hypoxic conditions.
25  ischemia caused elevation of the phospholipase A2
(1 time)
Biochemistry
(1 time)
CRH (1 time)
2010 Cardioprotective activity of urocortin by preventing caspase-independent, non-apoptotic death in cultured neonatal rat cardiomyocytes exposed to ischemia.
26  Islet Ca2+-independent phospholipase A2
(1 time)
Endocrinology
(1 time)
BEL (1 time)
2005 Inhibition of Ca2+-independent phospholipase A2 results in insufficient insulin secretion and impaired glucose tolerance.
27  isoform of phospholipase A2
(1 time)
Cardiology
(1 time)
NO (1 time)
2008 Ca2+-independent PLA2 controls endothelial store-operated Ca2+ entry and vascular tone in intact aorta.
28  isoform, Ca2+-independent cytosolic phospholipase A2
(1 time)
Drug Therapy
(1 time)
cPLA2 (1 time)
PLA2 (1 time)
TNF-alpha (1 time)
1997 Phospholipase A2 inhibitors in development.
29  isoforms of group VI phospholipase A2
(1 time)
Biochemistry
(1 time)
LH-iPLA2 (1 time)
SH-iPLA2 (1 time)
1999 Human pancreatic islets express mRNA species encoding two distinct catalytically active isoforms of group VI phospholipase A2 (iPLA2) that arise from an exon-skipping mechanism of alternative splicing of the transcript from the iPLA2 gene on chromosome 22q13.1.