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Abbreviation: int
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Long forms: 190

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Long Form No. Long Form Research Area Co-occurring Abbreviation PubMed/MEDLINE Info. (Year, Title)
in vitro CL
(37 times)
Pharmacology
(16 times)
CL (3 times)
AFE (2 times)
HLMs (2 times)
1995 Kinetics of diazepam metabolism in rat hepatic microsomes and hepatocytes and their use in predicting in vivo hepatic clearance.
integrase gene
(26 times)
Microbiology
(7 times)
att (2 times)
PAI (2 times)
ABC-F (1 time)
1993 Characterization of genetic elements required for site-specific integration of the temperate lactococcal bacteriophage phi LC3 and construction of integration-negative phi LC3 mutants.
interaction energy DeltaE
(11 times)
Chemistry
(10 times)
DFT (3 times)
S-T (2 times)
BDEs (1 time)
2005 Proton transfer of NH3-HCl catalyzed by only one molecule.
interaction DeltaE(≠)
(6 times)
Chemistry
(5 times)
DFT (1 time)
MMO (1 time)
OxIn (1 time)
2007 Transition-state energy and position along the reaction coordinate in an extended activation strain model.
independent of Q
(5 times)
Physiology
(3 times)
INT (1 time)
MRT (1 time)
PMR (1 time)
1988 Effect of a protein binding change on unbound and total plasma concentrations for drugs of intermediate hepatic extraction.
intestinal CL
(5 times)
Pharmacology
(2 times)
AUC (1 time)
DMIS (1 time)
2009 Pharmacokinetics of ipriflavone and its two metabolites, M1 and M5, after the intravenous and oral administration of ipriflavone to rat model of diabetes mellitus induced by streptozotocin.
intrinsic clearance, CL
(4 times)
Pharmacology
(2 times)
AUC (1 time)
CPF (1 time)
CPF-O (1 time)
2009 On the prediction of hepatic clearance using the diluted plasma in metabolic stability assay.
inspiratory R
(3 times)
Pulmonary Medicine
(1 time)
ATS (1 time)
ERS (1 time)
LMS (1 time)
2010 Reference ranges for interrupter resistance technique: the Asthma UK Initiative.
interaction P
(3 times)
Chemistry
(1 time)
BRIP1 (1 time)
comp (1 time)
SNPs (1 time)
2009 Polymorphisms in BRCA1, BRCA1-interacting genes and susceptibility of breast cancer in Chinese women.
10  intercostal muscles
(3 times)
Pulmonary Medicine
(3 times)
DI (3 times)
EMG (3 times)
CAS (1 time)
2002 Airflow limitation in asthmatic children assessed with a non-invasive EMG technique.
11  internal energies, E
(3 times)
Chemistry Techniques, Analytical
(2 times)
ESI (1 time)
ESI-MS (1 time)
2007 Gas phase noncovalent protein complexes that retain solution binding properties: Binding of xylobiose inhibitors to the beta-1, 4 exoglucanase from cellulomonas fimi.
12  I: With high variability in Cl
(2 times)
Pharmacology
(1 time)
--- 1998 An area correction method to reduce intrasubject variability in bioequivalence studies.
13  identified by comparing their sodA
(2 times)
Microbiology
(2 times)
--- 2005 Rapid and accurate identification of human isolates of Pasteurella and related species by sequencing the sodA gene.
14  in vitro and in vivo CL
(2 times)
Pharmacology
(2 times)
PT (1 time)
WS (1 time)
2004 Comparison of the use of liver models for predicting drug clearance using in vitro kinetic data from hepatic microsomes and isolated hepatocytes.
15  in vivo predicted CL
(2 times)
Pharmacology
(2 times)
BSA (1 time)
UGT (1 time)
2009 Prediction of drug clearance by glucuronidation from in vitro data: use of combined cytochrome P450 and UDP-glucuronosyltransferase cofactors in alamethicin-activated human liver microsomes.
16  indicating that DeltaE
(2 times)
Chemistry Techniques, Analytical
(1 time)
CDA (1 time)
CTCs (1 time)
DTT (1 time)
2006 A thermodynamic study on the complexation between riboflavin and a diaminotriazine derivative mediated by triple hydrogen bonds at water/oil interfaces.
17  integrin
(2 times)
Allergy and Immunology
(1 time)
DT104 (1 time)
invA (1 time)
RM (1 time)
2000 Detection of multidrug-resistant Salmonella typhimurium DT104 by multiplex polymerase chain reaction.
18  interacts, n
(2 times)
Chemistry
(2 times)
mon (6 times)
2005 Interaction of Ag(I), Hg(II), and Cu(II) with 1,2-ethanedithiol immobilized on chitosan: thermochemical data from isothermal calorimetry.
19  interleukin (IL)-2Rbeta(+) CD3
(2 times)
Allergy and Immunology
(1 time)
IL (2 times)
FACS (1 time)
IgM (1 time)
2006 Reasons why DBA/2 mice are resistant to malarial infection: expansion of CD3int B220+ gammadelta T cells with double-negative CD4- CD8- phenotype in the liver.
20  inverse correlation was found between R
(2 times)
Biochemistry
(1 time)
HLMs (1 time)
max (1 time)
MEFV (1 time)
2003 Applicability of interrupter resistance measurements using the MicroRint in daily practice.
21  (beta-NF)-induced RLM; meanwhile, the Cl
(1 time)
Chemistry
(1 time)
beta-NF (1 time)
DEX (1 time)
RLM (1 time)
2012 Stereoselective metabolism of tetrahydropalmatine enantiomers in rat liver microsomes.
22  anti-IL-2R beta mAb decreased the number of DX5(+) CD3
(1 time)
Allergy and Immunology
(1 time)
HSP65 (1 time)
IL-2R beta (1 time)
IL-4 (1 time)
2002 Roles of NKT cells in resistance against infection with Toxoplasma gondii and in expression of heat shock protein 65 in the host macrophages.
23  element-integrase gene
(1 time)
Anti-Bacterial Agents
(1 time)
ICEs (1 time)
2009 SXT-related integrating conjugative element and IncC plasmids in Vibrio cholerae O1 strains in Eastern Africa.
24  enzyme-inhibitor complexes, which are required for the calculations of DeltaE
(1 time)
Chemistry Techniques, Analytical
(1 time)
ESI (1 time)
2007 Gas phase noncovalent protein complexes that retain solution binding properties: Binding of xylobiose inhibitors to the beta-1, 4 exoglucanase from cellulomonas fimi.
25  I and hence tactic behavior are sensitive to both pH
(1 time)
Bacteriology
(1 time)
MCPs (1 time)
1982 Effects of pH and repellent tactic stimuli on protein methylation levels in Escherichia coli.
26  I was found to decrease when pH
(1 time)
Bacteriology
(1 time)
MCPs (1 time)
1982 Effects of pH and repellent tactic stimuli on protein methylation levels in Escherichia coli.
27  I* channel for all four wavelengths, but E
(1 time)
Chemistry
(1 time)
cc (1 time)
2011 Vibrationally resolved photofragment translational spectroscopy of CH3I from 277 to 304 nm with increasing effect of the hot band.
28  identified by determining the positions of their sodA
(1 time)
Microbiology
(1 time)
--- 1998 Identification of streptococci to species level by sequencing the gene encoding the manganese-dependent superoxide dismutase.
29  identified to be limited by the (acetate)
(1 time)
Biomedical Engineering
(1 time)
--- 2013 Metabolic engineering of Clostridium acetobutylicum ATCC 824 for the high-yield production of a biofuel composed of an isopropanol/butanol/ethanol mixture.
30  identify CD11b(+)Gr-1
(1 time)
Neoplasms
(1 time)
MCA (1 time)
NK (1 time)
WT (1 time)
2012 NLRP3 suppresses NK cell-mediated responses to carcinogen-induced tumors and metastases.
31  identify compounds with CL
(1 time)
Molecular Biology
(1 time)
OPLS (1 time)
PCA (1 time)
QSARs (1 time)
2013 In silico categorization of in vivo intrinsic clearance using machine learning.
32  identify here highly cycling Lin(-)c-Kit
(1 time)
Allergy and Immunology
(1 time)
DCs (1 time)
2007 Identification of clonogenic common Flt3+M-CSFR+ plasmacytoid and conventional dendritic cell progenitors in mouse bone marrow.
33  If the TMDD model predictions are not sensitive to k
(1 time)
Pharmacology
(1 time)
MM (1 time)
TMDD (1 time)
tot (1 time)
2010 Selection between Michaelis-Menten and target-mediated drug disposition pharmacokinetic models.
34  IL-10 production byTcells,IL-10-producing F4/80(+)CD11b(+)CD11c
(1 time)
Microbiology
(1 time)
CB (1 time)
Treg (1 time)
2013 A single strain of Clostridium butyricum induces intestinal IL-10-producing macrophages to suppress acute experimental colitis in mice.
35  IL-10 was found to be resident CD11b(+)Gr1
(1 time)
Allergy and Immunology
(1 time)
IL (1 time)
MDSCs (1 time)
STAT1 (1 time)
2013 STAT1-regulated lung MDSC-like cells produce IL-10 and efferocytose apoptotic neutrophils with relevance in resolution of bacterial pneumonia.
36  IL-10 was prominently produced by host- and donor-derived CD5
(1 time)
Allergy and Immunology
(1 time)
GVHD (1 time)
HSCT (1 time)
2014 Donor and host B cell-derived IL-10 contributes to suppression of graft-versus-host disease.
37  IL-18Ralpha(+) and either CD4(-)CD8(-) (DN) or CD8alphabeta
(1 time)
Hematology
(1 time)
MAIT (1 time)
2011 Human MAIT cells are xenobiotic-resistant, tissue-targeted, CD161hi IL-17-secreting T cells.
38  IL-1beta and TNF-alpha were higher in Ly-6C
(1 time)
Neurology
(1 time)
CNS (1 time)
EAE (1 time)
IL-1beta (1 time)
2014 In acute experimental autoimmune encephalomyelitis, infiltrating macrophages are immune activated, whereas microglia remain immune suppressed.
39  IL-22-producing RORgammathiNKp46+NK1.1
(1 time)
Allergy and Immunology
(1 time)
IL-22 (1 time)
2009 RORgammat and commensal microflora are required for the differentiation of mucosal interleukin 22-producing NKp46+ cells.
40  IL-2Rbeta+ NK1- TCR
(1 time)
Gastroenterology
(1 time)
MNC (1 time)
mRNA (1 time)
NK1 (1 time)
1997 Mouse liver T cells: their change with aging and in comparison with peripheral T cells.
41  IL-33-treated recipients exhibited increased CD11b(+) Gr-1
(1 time)
Allergy and Immunology
(1 time)
INT (1 time)
2011 IL-33 expands suppressive CD11b+ Gr-1(int) and regulatory T cells, including ST2L+ Foxp3+ cells, and mediates regulatory T cell-dependent promotion of cardiac allograft survival.
42  IL-4 production, whereas transfer of CD11c
(1 time)
Allergy and Immunology
(1 time)
DC (1 time)
2014 Helminth-conditioned dendritic cells prime CD4+ T cells to IL-4 production in vivo.
43  image constitute what we term the h
(1 time)
Diagnostic Imaging
(1 time)
--- 1996 A representation for mammographic image processing.
44  image, and examine the sensitivity of h
(1 time)
Diagnostic Imaging
(1 time)
--- 1996 A representation for mammographic image processing.
45  imaging process and the h
(1 time)
Diagnostic Imaging
(1 time)
--- 1996 A representation for mammographic image processing.
46  imipramine, clomipramine, and trimipramine, whereas CL
(1 time)
Pharmacology
(1 time)
UGT (1 time)
2010 Role of human UGT2B10 in N-glucuronidation of tricyclic antidepressants, amitriptyline, imipramine, clomipramine, and trimipramine.
47  immature neutrophilic CD11b(+) Ly-6C
(1 time)
Allergy and Immunology
(1 time)
--- 2013 Immature mouse granulocytic myeloid cells are characterized by production of ficolin-B.
48  impact of prediction uncertainty of CL
(1 time)
Toxicology
(1 time)
PL (1 time)
QPPR (1 time)
2012 Quantitative Property-Property Relationship for Screening-Level Prediction of Intrinsic Clearance of Volatile Organic Chemicals in Rats and Its Integration within PBPK Models to Predict Inhalation Pharmacokinetics in Humans.
49  impact of the lack of knowledge of CL
(1 time)
Toxicology
(1 time)
PL (1 time)
QPPR (1 time)
2012 Quantitative Property-Property Relationship for Screening-Level Prediction of Intrinsic Clearance of Volatile Organic Chemicals in Rats and Its Integration within PBPK Models to Predict Inhalation Pharmacokinetics in Humans.
50  impact on the measured values of x(c) and phi
(1 time)
Biophysics
(1 time)
IMRT (1 time)
MLC (1 time)
2011 Real-time verification of multileaf collimator-driven radiotherapy using a novel optical attenuation-based fluence monitor.
51  importance of a moderate DeltaG
(1 time)
Biochemistry
(1 time)
RRF (3 times)
2013 Thermodynamic assessment of domain-domain interactions and in vitro activities of mesophilic and thermophilic ribosome recycling factors.
52  important effect on both Cl
(1 time)
Biochemistry
(1 time)
GC (1 time)
HDC (1 time)
TC (1 time)
1988 Hepatic transport of bile acids in the isolated perfused rat liver. Structure-kinetic relationship.
53  important on the values of n
(1 time)
Chemistry
(1 time)
--- 2010 Direct determinations of energetic parameters at chitosan/Cr(VI) interfaces by means of immersion heat-conduction microcalorimetry.
54  improved significantly when using uptake CL
(1 time)
Toxicology
(1 time)
CL (1 time)
2012 Use of uptake intrinsic clearance from attached rat hepatocytes to predict hepatic clearance for poorly permeable compounds.
55  improvements were observed only when t
(1 time)
Natural Science Disciplines
(1 time)
--- 2014 Origin of the improved mobility and photo-bias stability in a double-channel metal oxide transistor.
56  IMRT segments, phi
(1 time)
Biophysics
(1 time)
IMRT (1 time)
MLC (1 time)
2011 Real-time verification of multileaf collimator-driven radiotherapy using a novel optical attenuation-based fluence monitor.
57  in silico estimated parameters, particularly when Cl
(1 time)
Chemistry
(1 time)
--- 2012 Prediction of the human oral bioavailability by using in vitro and in silico drug related parameters in a physiologically based absorption model.
58  in vitro data for Cl
(1 time)
Chemistry
(1 time)
--- 2012 Prediction of the human oral bioavailability by using in vitro and in silico drug related parameters in a physiologically based absorption model.
59  in vitro metabolic CL
(1 time)
Pharmacology
(1 time)
AFE (1 time)
CL (1 time)
mBcrp (1 time)
2010 Relationship between passive permeability, efflux, and predictability of clearance from in vitro metabolic intrinsic clearance.
60  in vitro recovery of CL
(1 time)
Pharmacology
(1 time)
ERY (1 time)
MDZ (1 time)
2010 Inhibition of CYP3A by erythromycin: in vitro-in vivo correlation in rats.
61  in vitro to measure pH
(1 time)
Gastroenterology
(1 time)
CF (1 time)
SNARF-1 (1 time)
2003 Direct measurement of acid permeation into rat oesophagus.
62  in vitro, but pH
(1 time)
Gastroenterology
(1 time)
CF (1 time)
SNARF-1 (1 time)
2003 Direct measurement of acid permeation into rat oesophagus.
63  in vivo hepatic metabolic CL
(1 time)
Pharmacology
(1 time)
AFE (1 time)
PHHs (1 time)
2016 Determination of Human Hepatocyte Intrinsic Clearance for Slowly Metabolized Compounds: Comparison of a Primary Hepatocyte/Stromal Cell Co-culture with Plated Primary Hepatocytes and HepaRG.
64  in vivo there was also a high correlation with CL
(1 time)
Toxicology
(1 time)
CZX (1 time)
HCZX (1 time)
2000 Chlorzoxazone: a probe drug whose metabolism can be used to monitor toluene exposure in rats.
65  inappropriate CL
(1 time)
Pharmacology
(1 time)
PB-IVIV (1 time)
2007 Prediction of human pharmacokinetics--evaluation of methods for prediction of hepatic metabolic clearance.
66  include both terminally differentiated, highly cytotoxic EOMES
(1 time)
Virology
(1 time)
ART (1 time)
EOMES (1 time)
hi (1 time)
2014 High eomesodermin expression among CD57+ CD8+ T cells identifies a CD8+ T cell subset associated with viral control during chronic human immunodeficiency virus infection.
67  including CD4(+)CTLA-4(+), CD4(+)IL10(+), CD4(+)CD25
(1 time)
Allergy and Immunology
(1 time)
DAS28 (1 time)
PB (1 time)
RA (1 time)
2009 Quantification and phenotype of regulatory T cells in rheumatoid arthritis according to disease activity score-28.
68  including morphology or 7-AAD staining: eg percentages of SytoR 16
(1 time)
Transplantation
(1 time)
7-AAD (1 time)
2001 Large populations of non-clonogenic early apoptotic CD34-positive cells are present in frozen-thawed peripheral blood stem cell transplants.
69  increase of the proportion of cells expressing the P
(1 time)
Genetics
(1 time)
--- 2012 Cellular variability of RpoS expression underlies subpopulation activation of an integrative and conjugative element.
70  increase with CL
(1 time)
Pharmacology
(1 time)
INT (1 time)
1988 Effect of a protein binding change on unbound and total plasma concentrations for drugs of intermediate hepatic extraction.
71  increased blood flow without pH
(1 time)
Gastroenterology
(1 time)
CAP (1 time)
CSAN (1 time)
LAF (1 time)
2010 Lafutidine, a protective H₂ receptor antagonist, enhances mucosal defense in rat esophagus.
72  increased disease activity and decreased levels of splenic CD11b(+)Gr-1
(1 time)
Allergy and Immunology
(1 time)
--- 2009 Autoantigen immunization at different sites reveals a role for anti-inflammatory effects of IFN-gamma in regulating susceptibility to experimental autoimmune encephalomyelitis.
73  increased the Km and decreased the CL
(1 time)
Pharmacology
(1 time)
DMSO (1 time)
2007 Effect of commonly used organic solvents on the kinetics of cytochrome P450 2B6- and 2C8-dependent activity in human liver microsomes.
74  increasing flake thickness was achieved due to the non-cumulative R
(1 time)
Nanotechnology
(1 time)
FET (1 time)
2015 Self-screened high performance multi-layer MoS₂ transistor formed by using a bottom graphene electrode.
75  increasing with decreasing Q
(1 time)
Botany
(1 time)
SP (1 time)
1999 Differences in chemical composition relative to functional differentiation between petioles and laminas of Fraxinus excelsior.
76  incrementally vary selected log K(x)
(1 time)
Environmental Health
(1 time)
DLM (1 time)
HFO (1 time)
LFER (1 time)
2009 Uranyl adsorption onto hydrous ferric oxide-A re-evaluation for the diffuse layer model database.
77  incubation at selected T
(1 time)
Chemistry
(1 time)
BSA (1 time)
DSC (1 time)
FTIR (1 time)
2011 Denaturation behaviors of two-state and non-two-state proteins examined by an interruption-incubation protocol.
78  incubations were consistent with its discrete CL
(1 time)
Pharmacology
(1 time)
PK (1 time)
2008 N-in-1 dosing pharmacokinetics in drug discovery: experience, theoretical and practical considerations.
79  incubations, the determination of Cl
(1 time)
Biochemistry
(1 time)
UGTs (1 time)
2005 Rapid simultaneous determination of metabolic clearance of multiple compounds catalyzed in vitro by recombinant human UDP-glucuronosyltransferases.
80  indefinitely but reached a second proliferative lifespan barrier, termed M
(1 time)
Cell Biology
(1 time)
--- 2003 Telomere-based proliferative lifespan barriers in Werner-syndrome fibroblasts involve both p53-dependent and p53-independent mechanisms.
81  indicate that the IL-7Ralpha(-)CD34(+)beta7
(1 time)
Allergy and Immunology
(1 time)
ILCs (1 time)
2013 Intestinal Lin- c-Kit+ NKp46- CD4- population strongly produces IL-22 upon IL-1beta stimulation.
82  indicate that, together, reductions in HR
(1 time)
Physiology
(1 time)
--- 2008 Decreased maximal heart rate with aging is related to reduced {beta}-adrenergic responsiveness but is largely explained by a reduction in intrinsic heart rate.
83  indicated by the delta
(1 time)
Chemistry
(1 time)
--- 2002 Interaction of indigo carmine dye with chitosan evaluated by adsorption and thermochemical data.
84  indicated fewer titratable groups with pK
(1 time)
Biochemistry
(1 time)
--- 1975 Titration study of acetylated lysozyme.
85  indicated that intermediate
(1 time)
Allergy and Immunology
(1 time)
IL (1 time)
mAb (1 time)
TCR (1 time)
1996 Cytotoxic activity against tumour cells mediated by intermediate TCR cells in the liver and spleen.
86  indicates that cryopreserved human hepatocytes systematically underpredict CL
(1 time)
Pharmacology
(1 time)
--- 2005 Prediction of metabolic clearance using cryopreserved human hepatocytes: kinetic characteristics for five benzodiazepines.
87  indicates that N-demethylation and 14-(R)-hydroxylation account for 65% of CL
(1 time)
Pharmacokinetics
(1 time)
CAM (1 time)
2003 CYP isoforms involved in the metabolism of clarithromycin in vitro: comparison between the identification from disappearance rate and that from formation rate of metabolites.
88  indirectly, PW
(1 time)
Physiology
(1 time)
--- 2011 Measured and predicted mechanical internal work in human locomotion.
89  individual cells that had activated P
(1 time)
Genetics
(1 time)
--- 2012 Cellular variability of RpoS expression underlies subpopulation activation of an integrative and conjugative element.
90  induced hyperaemia without changing pH
(1 time)
Gastroenterology
(1 time)
ASIC (1 time)
CA (1 time)
TRPV1 (1 time)
2008 CO2 chemosensing in rat oesophagus.
91  infiltrating skin, we observed CD11b(+)Ly-6C
(1 time)
Allergy and Immunology
(1 time)
BCG (1 time)
2010 Mycobacterium bovis bacillus Calmette-Guerin vaccination mobilizes innate myeloid-derived suppressor cells restraining in vivo T cell priming via IL-1R-dependent nitric oxide production.
92  inflammation is associated with high numbers of DR
(1 time)
Gastroenterology
(1 time)
CD (1 time)
DC (1 time)
LPMCs (1 time)
2016 Reduced numbers of mucosal DR(int) macrophages and increased numbers of CD103(+) dendritic cells during anti-TNF-alpha treatment in patients with Crohn's disease.
93  inflammatory Ly-6C
(1 time)
Allergy and Immunology
(1 time)
--- 2009 Gr-1 antibody induces STAT signaling, macrophage marker expression and abrogation of myeloid-derived suppressor cell activity in BM cells.
94  inflation volume of C
(1 time)
Biomedical Engineering
(1 time)
SR (1 time)
2004 [German Artificial Sphincter System--GASS. Development and in vitro evaluation of a novel, fully-implantable, highly integrated sphincter prosthesis for therapy of high-grade fecal incontinence].
95  influence metal association to QDs, but decreased (Cu)
(1 time)
Environmental Health
(1 time)
QDs (1 time)
2012 Cell-wall-dependent effect of carboxyl-CdSe/ZnS quantum dots on lead and copper availability to green microalgae.
96  influence of methodological differences on predicted R
(1 time)
Pulmonary Medicine
(1 time)
ATS (1 time)
ERS (1 time)
LMS (1 time)
2010 Reference ranges for interrupter resistance technique: the Asthma UK Initiative.
97  infusions was underestimated by measurements of pH
(1 time)
Cardiology
(1 time)
--- 1994 Correction of intramyocardial hypercarbic acidosis with sodium bicarbonate.
98  inhibited by quinidine, the CL
(1 time)
Drug Therapy
(1 time)
--- 2004 Effect of quinidine on the 10-hydroxylation of R-warfarin: species differences and clearance projection.
99  inhibitor further decreased Vv
(1 time)
Physiology
(1 time)
alpha-SMA (1 time)
NF-kappaB (1 time)
TNF-alpha (1 time)
1999 Role of TNFR1 and TNFR2 receptors in tubulointerstitial fibrosis of obstructive nephropathy.
100  inhibitory effect of cyclosporine on the CL
(1 time)
Pharmacology
(1 time)
HLMs (1 time)
rCYP (1 time)
2007 Metabolism of sirolimus in the presence or absence of cyclosporine by genotyped human liver microsomes and recombinant cytochromes P450 3A4 and 3A5.