1 |
mammalian target of rapamycin
(12239 times)
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Neoplasms (2224 times)
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PI3K (1611 times) AMPK (812 times) mTORC1 (432 times)
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1995 Isolation of a protein target of the FKBP12-rapamycin complex in mammalian cells.
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2 |
mammalian TOR
(34 times)
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Cell Biology (10 times)
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TOR (22 times) S6K1 (2 times) TORC1 (2 times)
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1999 Mammalian TOR controls one of two kinase pathways acting upon nPKCdelta and nPKCepsilon.
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3 |
molecular target of rapamycin
(21 times)
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Neoplasms (6 times)
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PI3K (4 times) CXCR4 (3 times) EGFR (3 times)
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2003 The molecular target of rapamycin (mTOR) as a therapeutic target against cancer.
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4 |
mammalian rapamycin target protein
(9 times)
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Pharmacology (2 times)
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p-mTOR (2 times) PI3K (2 times) RT-PCR (2 times)
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2017 [Occurrence, diagnosis and treatment of de novo gastrointestinal malignancies after organ transplantation].
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5 |
mechanistic target of rapamycin (serine/threonine kinase)
(6 times)
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Allergy and Immunology (2 times)
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PI3K (4 times) AKT (2 times) ALI (1 time)
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2014 New function of type I IFN: induction of autophagy.
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6 |
3-kinase-Akt-mechanistic target of rapamycin
(2 times)
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Pediatrics (1 time)
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BCAP (1 time) ccRCC (1 time) IL (1 time)
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2018 Renal Cell Carcinoma in von Hippel-Lindau Disease-From Tumor Genetics to Novel Therapeutic Strategies.
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7 |
mammalian target of sirolimus
(2 times)
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Drug Therapy (1 time)
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PBL (1 time) SRL (1 time) TDM (1 time)
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2002 Update on pharmacokinetic/pharmacodynamic studies with FTY720 and sirolimus.
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8 |
mechanistic (previously 'mammalian') target of rapamycin
(2 times)
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Neurology (1 time)
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TME (1 time)
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2016 The mTOR signalling cascade: paving new roads to cure neurological disease.
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9 |
mitochondrial target of rapamycin
(2 times)
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Molecular Biology (1 time)
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AM (1 time) GSK-3beta (1 time) IGF-1 (1 time)
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2011 PINK1 enhances insulin-like growth factor-1-dependent Akt signaling and protection against apoptosis.
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10 |
molecular target
(2 times)
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Rheumatology (1 time)
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PDB (1 time) Tfh (1 time) Th (1 time)
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2015 Activation of mTOR (mechanistic target of rapamycin) in rheumatic diseases.
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11 |
mTOR-complex
(2 times)
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Neurology (1 time)
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GBM (2 times) PI3K (2 times) EGFR (1 time)
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2016 PI3K/Akt/mTOR signaling pathway and targeted therapy for glioblastoma.
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12 |
Akt-mammalian TOR
(1 time)
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Biochemistry (1 time)
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OS (1 time)
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2014 C6 ceramide sensitizes pemetrexed-induced apoptosis and cytotoxicity in osteosarcoma cells.
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13 |
complex target of rapamycin
(1 time)
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Rheumatology (1 time)
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SLE (1 time) TSC (1 time)
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2015 Coincidence of tuberous sclerosis and systemic lupus erythematosus-a case report.
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14 |
downstream target of rapamycin
(1 time)
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Physiological Phenomena (1 time)
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BFR (1 time) ECC (1 time) S6K1 (1 time)
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2015 Blood flow restriction prevents muscle damage but not protein synthesis signaling following eccentric contractions.
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15 |
integrin-mechanistic target of the Rapamycin
(1 time)
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Cell Biology (1 time)
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BMSCs (1 time) LIPUS (1 time)
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2017 TGF-beta1-induced chondrogenesis of bone marrow mesenchymal stem cells is promoted by low-intensity pulsed ultrasound through the integrin-mTOR signaling pathway.
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16 |
m Target of Rapamycin
(1 time)
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Endocrinology (1 time)
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3-MA (1 time) 9-CPA (1 time) 9mA (1 time)
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2015 Monomethylated-adenines potentiate glucose-induced insulin production and secretion via inhibition of phosphodiesterase activity in rat pancreatic islets.
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17 |
M: echanistic T: arget of R: apamycin
(1 time)
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Neoplasms (1 time)
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---
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2015 Molecular Pathways: Increased Susceptibility to Infection Is a Complication of mTOR Inhibitor Use in Cancer Therapy.
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18 |
mammalian counterpart of TOR
(1 time)
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Cell Biology (1 time)
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ERK5 (1 time) TOR (1 time)
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2008 Integration of protein kinases mTOR and extracellular signal-regulated kinase 5 in regulating nucleocytoplasmic localization of NFATc4.
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19 |
mammalian homolog of target of rapamycin
(1 time)
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Pharmacology (1 time)
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AMPK (1 time)
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2005 AMPK, the metabolic syndrome and cancer.
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20 |
mammalian homolog of the Saccharomyces cerevisiae target of rapamycin proteins
(1 time)
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Biotechnology (1 time)
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eIF4E (1 time) FKBP (1 time) PKCdelta (1 time)
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2000 Functional interaction between RAFT1/FRAP/mTOR and protein kinase cdelta in the regulation of cap-dependent initiation of translation.
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21 |
mammalian rapamycin receptor
(1 time)
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Endocrinology (1 time)
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LVH (1 time) S6K1 (1 time) SHR (1 time)
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2021 mTOR inhibitor improves testosterone-induced myocardial hypertrophy in hypertensive rats.
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22 |
mammalian target of mammalian target rapamycin
(1 time)
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Pharmacology (1 time)
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NF-kappaB (1 time) PKM2 (1 time) PRAS40 (1 time)
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2021 Targeting PRAS40: a novel therapeutic strategy for human diseases.
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23 |
mammalian target of rapamycin is an evolutionarily conserved serine-threonine kinase
(1 time)
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Pharmacology (1 time)
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---
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2009 Effect of rapamycin on cue-induced drug craving in abstinent heroin addicts.
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24 |
mammalian target of rapamycin phosphorylation
(1 time)
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Genetics, Medical (1 time)
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LPS (1 time) siRNA (1 time)
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2018 The transcription factor cMaf is targeted by mTOR, and regulates the inflammatory response via the TLR4 signaling pathway.
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25 |
mammalian TOR homologue
(1 time)
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Biochemistry (1 time)
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---
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1995 TOR mutations confer rapamycin resistance by preventing interaction with FKBP12-rapamycin.
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26 |
mechanism by which a nutrient sensor
(1 time)
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Science (1 time)
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YY1 (1 time)
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2007 mTOR controls mitochondrial oxidative function through a YY1-PGC-1alpha transcriptional complex.
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27 |
mechanistic of rapamycin
(1 time)
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Neurology (1 time)
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AMPK (1 time) miRNAs (1 time) NCDs (1 time)
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2016 Harnessing the Power of SIRT1 and Non-coding RNAs in Vascular Disease.
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28 |
mechanistic target of rapamycin as it is known now
(1 time)
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Neoplasms (1 time)
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ASH (1 time) eIFs (1 time) HCC (1 time)
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2017 New liver cancer biomarkers: PI3K/AKT/mTOR pathway members and eukaryotic translation initiation factors.
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29 |
mechanistic TOR
(1 time)
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Cell Biology (1 time)
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TOR (1 time)
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2013 Duration of rapamycin treatment has differential effects on metabolism in mice.
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30 |
menopause, transplantologic age, CSD, previous glomerulonephritis, andmammalian target of rapamycin
(1 time)
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Transplantation (1 time)
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BMD (1 time) CSD (1 time) imTOR (1 time)
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2017 Understanding Bone Damage After Kidney Transplantation: ARetrospective Monocentric Cross Sectional Analysis.
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31 |
metabolic regulator
(1 time)
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Physiology (1 time)
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GOT (1 time) qRT-PCR (1 time) TG (1 time)
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2017 Preventive effect of L-carnitine on the disorder of lipid metabolism and circadian clock of mice subjected to chronic jet-lag.
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32 |
metabolism regulatory gene
(1 time)
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Reproductive Medicine (1 time)
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FDA (1 time) IMP (1 time) ROS (1 time)
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2019 Imperatorin improves invitro porcine embryo development by reducing oxidative stress and autophagy.
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33 |
metabolism, including serine/threonine-protein kinase TOR
(1 time)
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Genetics (1 time)
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HF (1 time) Mapk14a (1 time) SD (1 time)
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2022 A zebrafish ppargamma gene deletion reveals a protein kinase network associated with defective lipid metabolism.
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34 |
Methods: Level of rapamycin
(1 time)
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Cell Biology (1 time)
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BMDS (1 time) CA1 (1 time) CA3 (1 time)
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2022 Possible Involvement of DNA Methylation in TSC1 Gene Expression in Neuroprotection Induced by Hypoxic Preconditioning.
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35 |
mitogen-activated protein kinase
(1 time)
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Environmental Health (1 time)
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ER (1 time) MAPK (1 time) MPs (1 time)
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2021 The Kidney-Related Effects of Polystyrene Microplastics on Human Kidney Proximal Tubular Epithelial Cells HK-2 and Male C57BL/6 Mice.
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36 |
modification of an immunosuppressive regimen with introduction of rapamycin
(1 time)
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Nephrology (1 time)
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CNIs (1 time) SCC (1 time)
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2021 Rapamycin Inhibitors for Eye Squamous Cell Carcinoma after Renal Transplantation: A Case Report.
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37 |
modulation of key molecules of the rapamycin
(1 time)
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Biomedical Research (1 time)
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ANOVA (1 time) PI3K (1 time) PTEN (1 time)
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2020 Wubeizi Ointment Suppresses Keloid Formation through Modulation of the mTOR Pathway.
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38 |
monoclonal antibody rituximab, calcineurin inhibitors like cyclosporine and tacrolimus, rapamycin
(1 time)
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Endocrinology (1 time)
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MMF (1 time)
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2022 Immunosuppressed non-responders to two doses of mRNA SARS-CoV-2 vaccines achieve an immune response comparable to those of immunocompetent individuals after a third dose.
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39 |
monophosphate- activated protein kinase and the rapamycin kinase
(1 time)
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Biology (1 time)
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C-PC (1 time) NBR2 (1 time) NSCLC (1 time)
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2022 C-Phycocyanin Suppresses Cell Proliferation and Promotes Apoptosis by Regulating the AMPK Pathway in NCL-H292 Non-Small Cell Lung Cancer Cells.
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40 |
more effective than the rapamycin
(1 time)
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Biomedical Engineering (1 time)
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PPARalpha (1 time) TSC (1 time) Vif (1 time)
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2010 Systems analysis of small signaling modules relevant to eight human diseases.
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41 |
most patients receive sunitinib or amammalian target of rapamycin
(1 time)
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Neoplasms (1 time)
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DCR (1 time) mpRCC (1 time) OS (1 time)
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2021 Everolimus or sunitinib as first-line treatment of metastatic papillary renal cell carcinoma: A retrospective study of the GETUG group (Groupe d'Etude des Tumeurs Uro-Genitales).
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42 |
MS and for drug and target protein
(1 time)
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Pharmacology (1 time)
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---
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2018 Defining drug and target protein distributions after stent-based drug release: Durable versus deployable coatings.
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43 |
mTOR Complex; RAS, Rat sarcoma; RAF, rapidly accelerated fibrosarcoma
(1 time)
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Hematology (1 time)
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MB (1 time)
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2015 Metastatic Group 3 Medulloblastoma in a Patient With Tuberous Sclerosis Complex: Case Description and Molecular Characterization of the Tumor.
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44 |
mTOR ODNs to suppress mammalian target rapamycin
(1 time)
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Chemistry (1 time)
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ncRNAs (1 time) ODNs (1 time) UUO (1 time)
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2022 Synthetic Non-Coding RNA for Suppressing mTOR Translation to Prevent Renal Fibrosis Related to Autophagy in UUO Mouse Model.
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45 |
muscle protein synthesis
(1 time)
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Nutritional Sciences (1 time)
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MAFbx (1 time) MuRF-1 (1 time)
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2014 Whey protein modifies gene expression related to protein metabolism affecting muscle weight in resistance-exercised rats.
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46 |
MXene-Matrigel potentiates the amycin
(1 time)
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Biomedical Research (1 time)
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Cochlea-Orgs (1 time) SGNs (1 time)
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2022 Ti3 C2 Tx MXene Composite 3D Hydrogel Potentiates mTOR Signaling to Promote the Generation of Functional Hair Cells in Cochlea Organoids.
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47 |
phosphatidylinositol-3-kinase-AKT-mechanistic target of rapamycin
(1 time)
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Biology (1 time)
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endo-lysosomes (1 time) LPS (1 time) mTORC1 (1 time)
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2019 Enhanced translation expands the endo-lysosome size and promotes antigen presentation during phagocyte activation.
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48 |
ubiquitin-mediated proteolysis, rapamycin
(1 time)
|
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Gal (1 time) GalNAc (1 time)
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2022 Quantitative Proteomics Reveals Metabolic Reprogramming in Host Cells Induced by Trophozoites and Intermediate Subunit of Gal/GalNAc Lectins from Entamoeba histolytica.
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