1 |
retinoblastoma protein
(847 times)
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Neoplasms (225 times)
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CDK (87 times) CDKs (37 times) HPV (27 times)
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1991 Antibodies specific for the human retinoblastoma protein identify a family of related polypeptides.
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2 |
phosphorylated retinoblastoma
(29 times)
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Neoplasms (9 times)
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CDK (6 times) PCNA (4 times) 3'-UTR (2 times)
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2002 Cyclooxygenase (COX)-2 and cell cycle activity in a transgenic mouse model of Alzheimer's disease neuropathology.
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3 |
Rb protein
(23 times)
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Neoplasms (8 times)
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Rb (7 times) CDK (3 times) 5-aza-dC (1 time)
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1993 Effect of sodium butyrate on the expression of retinoblastoma (RB1) and P53 gene and phosphorylation of retinoblastoma protein in human colon tumor cell line HT29.
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4 |
product of the retinoblastoma gene
(15 times)
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Molecular Biology (6 times)
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ADH (1 time) CDK (1 time) CDK9 (1 time)
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1992 Transforming growth factor beta 1 regulation of c-myc expression, pRB phosphorylation, and cell cycle progression in keratinocytes.
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5 |
protein retinoblastoma
(13 times)
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Neoplasms (6 times)
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ADC (1 time) ANM (1 time) CDK (1 time)
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1999 Decreased retinoblastoma protein expression in gamma-irradiated mouse ovarian follicles.
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6 |
product of the retinoblastoma tumor suppressor gene
(12 times)
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Neoplasms (4 times)
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CDKs (2 times) Ad (1 time) B-CLL (1 time)
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1989 Molecular mechanisms of transformation by the human papillomaviruses.
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7 |
phosphorylated Rb
(9 times)
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Molecular Biology (2 times)
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CDK (3 times) Rb (3 times) 3-MA (1 time)
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2010 Reversible regulation of the retinoblastoma protein/E2F-1 pathway during "reverse cardiac remodelling" after ventricular unloading.
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8 |
phospho-Rb
(7 times)
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Cell Biology (3 times)
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Rb (2 times) 5-FU (1 time) CgA (1 time)
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2008 Expression and localization of Ski determine cell type-specific TGFbeta signaling effects on the cell cycle.
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9 |
phospho-retinoblastoma
(6 times)
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Cell Biology (2 times)
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Rb (2 times) BDNF (1 time) BM-MSC (1 time)
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2001 Role of inducible heat shock protein 70 in radiation-induced cell death.
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10 |
protein encoded by retinoblastoma susceptibility gene
(3 times)
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Hematology (2 times)
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BrdUrd (1 time) G-CSF (1 time) PBPC (1 time)
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1994 [Cyclins and proliferative pathology].
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11 |
phosphorylated retinoblastoma tumor-suppressor protein
(2 times)
|
Neoplasms (2 times)
|
Akt (1 time) CAK (1 time) MAT1 (1 time)
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2004 MAT1-modulated cyclin-dependent kinase-activating kinase activity cross-regulates neuroblastoma cell G1 arrest and neurite outgrowth.
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12 |
plant homolog of the tumor suppressor Retinoblastoma
(2 times)
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Biology (1 time)
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RBR (2 times) MET1 (1 time) PRC2 (1 time)
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2008 A dynamic reciprocal RBR-PRC2 regulatory circuit controls Arabidopsis gametophyte development.
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13 |
proteins related to the retinoblastoma tumor suppressor protein
(2 times)
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Molecular Biology (1 time)
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---
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1998 The retinoblastoma protein is essential for cyclin A repression in quiescent cells.
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14 |
multi-protein complex and the retinoblastoma
(1 time)
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Virology (1 time)
|
---
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2013 Interaction of CtBP with adenovirus E1A suppresses immortalization of primary epithelial cells and enhances virus replication during productive infection.
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15 |
non-phosphorylated band of retinoblastoma protein
(1 time)
|
Chemistry (1 time)
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PD (1 time)
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2008 Intracellular signaling pathways involved in post-mitotic dopaminergic PC12 cell death induced by 6-hydroxydopamine.
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16 |
p21-associated retinoblastoma protein
(1 time)
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Gastroenterology (1 time)
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CDK (1 time)
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2003 Regulation and role of p21 and p27 cyclin-dependent kinase inhibitors during hepatocyte differentiation and growth.
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17 |
part through collaboration with the retinoblastoma
(1 time)
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Molecular Biology (1 time)
|
---
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2009 E2f3b plays an essential role in myogenic differentiation through isoform-specific gene regulation.
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18 |
part, to the inactivation of the retinoblastoma
(1 time)
|
Molecular Biology (1 time)
|
IRBP (1 time)
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1994 Apoptosis or retinoblastoma: alternative fates of photoreceptors expressing the HPV-16 E7 gene in the presence or absence of p53.
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19 |
pathway and the retinoblastoma
(1 time)
|
Molecular Biology (1 time)
|
---
|
1999 Tissue-specific alternative splicing in the human INK4a/ARF cell cycle regulatory locus.
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20 |
pathways both leading to retinoblastoma protein
(1 time)
|
Neoplasms (1 time)
|
HCC (1 time)
|
2009 Senescence and immortality in hepatocellular carcinoma.
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21 |
PDGF-BB-induced phosphorylation of retinoblastoma protein
(1 time)
|
Cardiology (1 time)
|
CDKs (1 time) PDGF-BB (1 time) RASMCs (1 time)
|
2009 Antiproliferative action of cudraflavone B, isolated from Cudrania tricuspidata, through the downregulation of pRb phosphorylation in aortic smooth muscle cell proliferation signaling.
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22 |
perform LT functions related to interactions with retinoblastoma susceptibility gene
(1 time)
|
Virology (1 time)
|
CyT (1 time) LT (1 time)
|
1996 Genetic analysis of polyomavirus large T nuclear localization: nuclear localization is required for productive association with pRb family members.
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23 |
phosphoproteins related to the retinoblastoma gene product
(1 time)
|
Virology (1 time)
|
MEFs (1 time) SV40 (1 time) Tag (1 time)
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1996 Simian virus 40 large T antigen alters the phosphorylation state of the RB-related proteins p130 and p107.
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24 |
phosphorylated retinoblastoma protein expression
(1 time)
|
Reproductive Medicine (1 time)
|
HPV (1 time) siRNA (1 time)
|
2007 Silencing of HPV 18 oncoproteins With RNA interference causes growth inhibition of cervical cancer cells.
|
25 |
phosphorylates and inactivates the retinoblastoma
(1 time)
|
Medicine (1 time)
|
siRNA (1 time)
|
2008 ErbB2 induces Notch1 activity and function in breast cancer cells.
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26 |
phosphorylating key substrates, including the retinoblastoma tumor suppressor gene products
(1 time)
|
Hematology (1 time)
|
CDKs (1 time)
|
1997 Control of G1 progression by D-type cyclins: key event for cell proliferation.
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27 |
phosphorylation of Rb protein
(1 time)
|
Biochemistry (1 time)
|
---
|
1992 Abundance and state of phosphorylation of the retinoblastoma susceptibility gene product in human colon cancer.
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28 |
phosphorylation of the retinoblastoma tumor suppressor
(1 time)
|
Nephrology (1 time)
|
MCs (1 time) TGF-beta1 (1 time)
|
1997 TGF-beta1-induced cell cycle arrest in renal mesangial cells involves inhibition of cyclin E-cdk 2 activation and retinoblastoma protein phosphorylation.
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29 |
phosphorylation of the tumor suppressor retinoblastoma
(1 time)
|
Neoplasms (1 time)
|
ARB (1 time) CDK4 (1 time) EGFR (1 time)
|
2020 Antihypertensive drug telmisartan suppresses the proliferation of gastric cancer cells invitro and invivo.
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30 |
phosphorylation state of the Retinoblastoma gene product
(1 time)
|
Molecular Biology (1 time)
|
---
|
1995 Heat treatment induces dephosphorylation of pRb and dissociation of T-antigen/pRb complex during transforming infection with SV40.
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31 |
phosphorylation/inactivation of the retinoblastoma
(1 time)
|
Neoplasms (1 time)
|
---
|
2003 The tyrphostin AG1024 accelerates the degradation of phosphorylated forms of retinoblastoma protein (pRb) and restores pRb tumor suppressive function in melanoma cells.
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32 |
Pml regulated the subcellular distribution of the retinoblastoma protein
(1 time)
|
Neurology (1 time)
|
NPCs (1 time)
|
2009 The tumor suppressor Pml regulates cell fate in the developing neocortex.
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33 |
polymerase degradation, and underphosphorylation of the retinoblastoma protein
(1 time)
|
Neoplasms (1 time)
|
ara-C (2 times)
|
1999 Dysregulation of the cyclin-dependent kinase inhibitor p21WAF1/CIP1/MDA6 increases the susceptibility of human leukemia cells (U937) to 1-beta-D-arabinofuranosylcytosine-mediated mitochondrial dysfunction and apoptosis.
|
34 |
potential role of retinoblastoma protein
(1 time)
|
Cell Biology (1 time)
|
Rb (1 time)
|
1997 Stage-specific expression and phosphorylation of retinoblastoma protein (pRb) in the rat seminiferous epithelium.
|
35 |
presence of a non-functional retinoblastoma protein
(1 time)
|
Molecular Biology (1 time)
|
HCC (1 time)
|
1997 Resistance to p53-mediated growth arrest and apoptosis in Hep 3B hepatoma cells.
|
36 |
Previously, we reported that breast cancer cells with retinoblastoma
(1 time)
|
Neoplasms (1 time)
|
CDK4 (1 time) MEFs (1 time)
|
2006 The differential staurosporine-mediated G1 arrest in normal versus tumor cells is dependent on the retinoblastoma protein.
|
37 |
principally regulated by its temporal association with retinoblastoma pocket protein
(1 time)
|
Molecular Biology (1 time)
|
CDK (1 time)
|
2005 E2F transcription factors and pRb pocket proteins in cell cycle progression.
|
38 |
process requires a functional retinoblastoma
(1 time)
|
Biochemistry (1 time)
|
PI (1 time)
|
2002 The expression of keratin k10 in the basal layer of the epidermis inhibits cell proliferation and prevents skin tumorigenesis.
|
39 |
product of the tumor suppressor gene retinoblastoma
(1 time)
|
Virology (1 time)
|
HPV-1 (1 time)
|
2001 Induction of pRb degradation by the human papillomavirus type 16 E7 protein is essential to efficiently overcome p16INK4a-imposed G1 cell cycle Arrest.
|
40 |
progression by interacting with the retinoblastoma gene product
(1 time)
|
Pathology (1 time)
|
MCLs (1 time)
|
1996 Expression of retinoblastoma gene product (pRb) in mantle cell lymphomas. Correlation with cyclin D1 (PRAD1/CCND1) mRNA levels and proliferative activity.
|
41 |
progressors, with increases in the levels of retinoblastoma
(1 time)
|
Cell Biology (1 time)
|
DPP2 (1 time)
|
2009 Dipeptidyl peptidase 2 is an essential survival factor in the regulation of cell quiescence.
|
42 |
proliferation, retinoblastoma
(1 time)
|
Virology (1 time)
|
CDK2 (1 time) HPV-1 (1 time)
|
2004 Human papillomavirus type 16 E6 promotes retinoblastoma protein phosphorylation and cell cycle progression.
|
43 |
protein expression, including retinoblastoma
(1 time)
|
Reproductive Medicine (1 time)
|
CDK4 (1 time) MTT (1 time)
|
2005 Contragestazol (DL111-IT) inhibits proliferation of human androgen-independent prostate cancer cell line PC3 in vitro and in vivo.
|
44 |
protein Rb
(1 time)
|
Neoplasms (1 time)
|
TBLR1 (1 time)
|
2014 Transducin (beta)-like 1 X-linked receptor 1 promotes proliferation and tumorigenicity in human breast cancer via activation of beta-catenin signaling.
|
45 |
proteins from the retinoblastoma
(1 time)
|
Geriatrics (1 time)
|
AD (1 time) ALS (1 time)
|
2001 Hyperphosphorylation of the retinoblastoma gene product and altered subcellular distribution of E2F-1 during Alzheimer's disease and amyotrophic lateral sclerosis.
|
46 |
proteins involved in the retinoblastoma
(1 time)
|
Pathology (1 time)
|
SDC (1 time)
|
2003 Salivary duct carcinoma: immunohistochemical profile of an aggressive salivary gland tumour.
|
47 |
proteins such as retinoblastoma
(1 time)
|
Pathology (1 time)
|
HPV (1 time) SILs (1 time)
|
2002 Changes in retinoblastoma gene expression during cervical cancer progression.
|
48 |
proteins that bypass the retinoblastoma
(1 time)
|
Cell Biology (1 time)
|
Cip1 (1 time)
|
2004 RhoE inhibits cell cycle progression and Ras-induced transformation.
|
49 |
provides a link between the retinoblastoma
(1 time)
|
Cell Biology (1 time)
|
---
|
2007 E2F-dependent induction of p14ARF during cell cycle re-entry in human T cells.
|
50 |
PVs cause neoplastic transformation by inhibiting retinoblastoma
(1 time)
|
Pathology (1 time)
|
PV (1 time) SCCs (1 time) UV-exposed (1 time)
|
2012 Loss of retinoblastoma protein, but not p53, is associated with the presence of papillomaviral DNA in feline viral plaques, Bowenoid in situ carcinomas, and squamous cell carcinomas.
|
51 |
RB-associated protein
(1 time)
|
Ophthalmology (1 time)
|
Rb (1 time)
|
2018 Immunohistochemical assay for neuron-specific enolase, synaptophysin, and RB-associated protein as a diagnostic aid in advanced retinoblastomas.
|
52 |
Rb1-encoded protein
(1 time)
|
Molecular Biology (1 time)
|
---
|
2006 The retinoblastoma tumor-suppressor gene, the exception that proves the rule.
|
53 |
readily phosphorylated the retinoblastoma protein
(1 time)
|
Cell Biology (1 time)
|
CDK4 (1 time)
|
1994 D-type cyclin-dependent kinase activity in mammalian cells.
|
54 |
substrate-retinoblastoma protein
(1 time)
|
Cell Biology (1 time)
|
cdk's (1 time)
|
1998 [Dependence of the process leading to phosphorylation of retinoblastoma protein (pRb) on the status of the actin cytoskeleton].
|