| 1 |
retinoblastoma protein
(822 times)
|
Neoplasms
(219 times)
|
CDK (85 times)
CDKs (36 times)
HPV (25 times)
|
1991 Antibodies specific for the human retinoblastoma protein identify a family of related polypeptides.
|
| 2 |
phosphorylated retinoblastoma
(27 times)
|
Neoplasms
(9 times)
|
CDK (6 times)
PCNA (4 times)
3'-UTR (2 times)
|
2002 Cyclooxygenase (COX)-2 and cell cycle activity in a transgenic mouse model of Alzheimer's disease neuropathology.
|
| 3 |
Rb protein
(22 times)
|
Neoplasms
(8 times)
|
Rb (6 times)
CDK (2 times)
5-aza-dC (1 time)
|
1993 Effect of sodium butyrate on the expression of retinoblastoma (RB1) and P53 gene and phosphorylation of retinoblastoma protein in human colon tumor cell line HT29.
|
| 4 |
product of the retinoblastoma gene
(15 times)
|
Molecular Biology
(6 times)
|
ADH (1 time)
CDK (1 time)
CDK9 (1 time)
|
1992 Transforming growth factor beta 1 regulation of c-myc expression, pRB phosphorylation, and cell cycle progression in keratinocytes.
|
| 5 |
protein retinoblastoma
(13 times)
|
Neoplasms
(6 times)
|
ADC (1 time)
ANM (1 time)
CDK (1 time)
|
1999 Decreased retinoblastoma protein expression in gamma-irradiated mouse ovarian follicles.
|
| 6 |
product of the retinoblastoma tumor suppressor gene
(12 times)
|
Neoplasms
(4 times)
|
CDKs (2 times)
Ad (1 time)
B-CLL (1 time)
|
1989 Molecular mechanisms of transformation by the human papillomaviruses.
|
| 7 |
phosphorylated Rb
(7 times)
|
Science
(1 time)
|
CDK (3 times)
Rb (3 times)
ATCs (1 time)
|
2010 Reversible regulation of the retinoblastoma protein/E2F-1 pathway during "reverse cardiac remodelling" after ventricular unloading.
|
| 8 |
phospho-retinoblastoma
(5 times)
|
Cell Biology
(2 times)
|
Rb (2 times)
BDNF (1 time)
BM-MSC (1 time)
|
2001 Role of inducible heat shock protein 70 in radiation-induced cell death.
|
| 9 |
phosphorylated retinoblastoma tumor-suppressor protein
(2 times)
|
Neoplasms
(2 times)
|
Akt (1 time)
CAK (1 time)
MAT1 (1 time)
|
2004 MAT1-modulated cyclin-dependent kinase-activating kinase activity cross-regulates neuroblastoma cell G1 arrest and neurite outgrowth.
|
| 10 |
plant homolog of the tumor suppressor Retinoblastoma
(2 times)
|
Biology
(1 time)
|
RBR (2 times)
MET1 (1 time)
PRC2 (1 time)
|
2008 A dynamic reciprocal RBR-PRC2 regulatory circuit controls Arabidopsis gametophyte development.
|
| 11 |
protein encoded by the retinoblastoma susceptibility gene
(2 times)
|
Cell Biology
(1 time)
|
PHA (1 time)
|
1994 [Cyclins and proliferative pathology].
|
| 12 |
proteins related to the retinoblastoma tumor suppressor protein
(2 times)
|
Molecular Biology
(1 time)
|
---
|
1998 The retinoblastoma protein is essential for cyclin A repression in quiescent cells.
|
| 13 |
multi-protein complex and the retinoblastoma
(1 time)
|
Virology
(1 time)
|
---
|
2013 Interaction of CtBP with adenovirus E1A suppresses immortalization of primary epithelial cells and enhances virus replication during productive infection.
|
| 14 |
non-phosphorylated band of retinoblastoma protein
(1 time)
|
Chemistry
(1 time)
|
PD (1 time)
|
2008 Intracellular signaling pathways involved in post-mitotic dopaminergic PC12 cell death induced by 6-hydroxydopamine.
|
| 15 |
p21-associated retinoblastoma protein
(1 time)
|
Gastroenterology
(1 time)
|
CDK (1 time)
|
2003 Regulation and role of p21 and p27 cyclin-dependent kinase inhibitors during hepatocyte differentiation and growth.
|
| 16 |
part through collaboration with the retinoblastoma
(1 time)
|
Molecular Biology
(1 time)
|
---
|
2009 E2f3b plays an essential role in myogenic differentiation through isoform-specific gene regulation.
|
| 17 |
part, to the inactivation of the retinoblastoma
(1 time)
|
Molecular Biology
(1 time)
|
IRBP (1 time)
|
1994 Apoptosis or retinoblastoma: alternative fates of photoreceptors expressing the HPV-16 E7 gene in the presence or absence of p53.
|
| 18 |
pathway and the retinoblastoma
(1 time)
|
Molecular Biology
(1 time)
|
---
|
1999 Tissue-specific alternative splicing in the human INK4a/ARF cell cycle regulatory locus.
|
| 19 |
pathways both leading to retinoblastoma protein
(1 time)
|
Neoplasms
(1 time)
|
HCC (1 time)
|
2009 Senescence and immortality in hepatocellular carcinoma.
|
| 20 |
PDGF-BB-induced phosphorylation of retinoblastoma protein
(1 time)
|
Cardiology
(1 time)
|
CDKs (1 time)
PDGF-BB (1 time)
RASMCs (1 time)
|
2009 Antiproliferative action of cudraflavone B, isolated from Cudrania tricuspidata, through the downregulation of pRb phosphorylation in aortic smooth muscle cell proliferation signaling.
|
| 21 |
perform LT functions related to interactions with retinoblastoma susceptibility gene
(1 time)
|
Virology
(1 time)
|
CyT (1 time)
LT (1 time)
|
1996 Genetic analysis of polyomavirus large T nuclear localization: nuclear localization is required for productive association with pRb family members.
|
| 22 |
phosphoproteins related to the retinoblastoma gene product
(1 time)
|
Virology
(1 time)
|
MEFs (1 time)
SV40 (1 time)
Tag (1 time)
|
1996 Simian virus 40 large T antigen alters the phosphorylation state of the RB-related proteins p130 and p107.
|
| 23 |
phosphorylated retinoblastoma protein expression
(1 time)
|
Reproductive Medicine
(1 time)
|
HPV (1 time)
siRNA (1 time)
|
2007 Silencing of HPV 18 oncoproteins With RNA interference causes growth inhibition of cervical cancer cells.
|
| 24 |
phosphorylates and inactivates the retinoblastoma
(1 time)
|
Medicine
(1 time)
|
siRNA (1 time)
|
2008 ErbB2 induces Notch1 activity and function in breast cancer cells.
|
| 25 |
phosphorylating key substrates, including the retinoblastoma tumor suppressor gene products
(1 time)
|
Hematology
(1 time)
|
CDKs (1 time)
|
1997 Control of G1 progression by D-type cyclins: key event for cell proliferation.
|
| 26 |
phosphorylation of Rb protein
(1 time)
|
Biochemistry
(1 time)
|
---
|
1992 Abundance and state of phosphorylation of the retinoblastoma susceptibility gene product in human colon cancer.
|
| 27 |
phosphorylation of the retinoblastoma tumor suppressor
(1 time)
|
Nephrology
(1 time)
|
MCs (1 time)
TGF-beta1 (1 time)
|
1997 TGF-beta1-induced cell cycle arrest in renal mesangial cells involves inhibition of cyclin E-cdk 2 activation and retinoblastoma protein phosphorylation.
|
| 28 |
phosphorylation state of the Retinoblastoma gene product
(1 time)
|
Molecular Biology
(1 time)
|
---
|
1995 Heat treatment induces dephosphorylation of pRb and dissociation of T-antigen/pRb complex during transforming infection with SV40.
|
| 29 |
phosphorylation/inactivation of the retinoblastoma
(1 time)
|
Neoplasms
(1 time)
|
---
|
2003 The tyrphostin AG1024 accelerates the degradation of phosphorylated forms of retinoblastoma protein (pRb) and restores pRb tumor suppressive function in melanoma cells.
|
| 30 |
Pml regulated the subcellular distribution of the retinoblastoma protein
(1 time)
|
Neurology
(1 time)
|
NPCs (1 time)
|
2009 The tumor suppressor Pml regulates cell fate in the developing neocortex.
|
| 31 |
polymerase degradation, and underphosphorylation of the retinoblastoma protein
(1 time)
|
Neoplasms
(1 time)
|
ara-C (2 times)
|
1999 Dysregulation of the cyclin-dependent kinase inhibitor p21WAF1/CIP1/MDA6 increases the susceptibility of human leukemia cells (U937) to 1-beta-D-arabinofuranosylcytosine-mediated mitochondrial dysfunction and apoptosis.
|
| 32 |
potential role of retinoblastoma protein
(1 time)
|
Cell Biology
(1 time)
|
Rb (1 time)
|
1997 Stage-specific expression and phosphorylation of retinoblastoma protein (pRb) in the rat seminiferous epithelium.
|
| 33 |
presence of a non-functional retinoblastoma protein
(1 time)
|
Molecular Biology
(1 time)
|
HCC (1 time)
|
1997 Resistance to p53-mediated growth arrest and apoptosis in Hep 3B hepatoma cells.
|
| 34 |
Previously, we reported that breast cancer cells with retinoblastoma
(1 time)
|
Neoplasms
(1 time)
|
CDK4 (1 time)
MEFs (1 time)
|
2006 The differential staurosporine-mediated G1 arrest in normal versus tumor cells is dependent on the retinoblastoma protein.
|
| 35 |
principally regulated by its temporal association with retinoblastoma pocket protein
(1 time)
|
Molecular Biology
(1 time)
|
CDK (1 time)
|
2005 E2F transcription factors and pRb pocket proteins in cell cycle progression.
|
| 36 |
process requires a functional retinoblastoma
(1 time)
|
Biochemistry
(1 time)
|
PI (1 time)
|
2002 The expression of keratin k10 in the basal layer of the epidermis inhibits cell proliferation and prevents skin tumorigenesis.
|
| 37 |
product of the tumor suppressor gene retinoblastoma
(1 time)
|
Virology
(1 time)
|
HPV-1 (1 time)
|
2001 Induction of pRb degradation by the human papillomavirus type 16 E7 protein is essential to efficiently overcome p16INK4a-imposed G1 cell cycle Arrest.
|
| 38 |
progression by interacting with the retinoblastoma gene product
(1 time)
|
Pathology
(1 time)
|
MCLs (1 time)
|
1996 Expression of retinoblastoma gene product (pRb) in mantle cell lymphomas. Correlation with cyclin D1 (PRAD1/CCND1) mRNA levels and proliferative activity.
|
| 39 |
progressors, with increases in the levels of retinoblastoma
(1 time)
|
Cell Biology
(1 time)
|
DPP2 (1 time)
|
2009 Dipeptidyl peptidase 2 is an essential survival factor in the regulation of cell quiescence.
|
| 40 |
proliferation, retinoblastoma
(1 time)
|
Virology
(1 time)
|
CDK2 (1 time)
HPV-1 (1 time)
|
2004 Human papillomavirus type 16 E6 promotes retinoblastoma protein phosphorylation and cell cycle progression.
|
| 41 |
protein expression, including retinoblastoma
(1 time)
|
Reproductive Medicine
(1 time)
|
CDK4 (1 time)
MTT (1 time)
|
2005 Contragestazol (DL111-IT) inhibits proliferation of human androgen-independent prostate cancer cell line PC3 in vitro and in vivo.
|
| 42 |
protein Rb
(1 time)
|
Neoplasms
(1 time)
|
TBLR1 (1 time)
|
2014 Transducin (beta)-like 1 X-linked receptor 1 promotes proliferation and tumorigenicity in human breast cancer via activation of beta-catenin signaling.
|
| 43 |
proteins from the retinoblastoma
(1 time)
|
Geriatrics
(1 time)
|
AD (1 time)
ALS (1 time)
|
2001 Hyperphosphorylation of the retinoblastoma gene product and altered subcellular distribution of E2F-1 during Alzheimer's disease and amyotrophic lateral sclerosis.
|
| 44 |
proteins involved in the retinoblastoma
(1 time)
|
Pathology
(1 time)
|
SDC (1 time)
|
2003 Salivary duct carcinoma: immunohistochemical profile of an aggressive salivary gland tumour.
|
| 45 |
proteins such as retinoblastoma
(1 time)
|
Pathology
(1 time)
|
HPV (1 time)
SILs (1 time)
|
2002 Changes in retinoblastoma gene expression during cervical cancer progression.
|
| 46 |
proteins that bypass the retinoblastoma
(1 time)
|
Cell Biology
(1 time)
|
Cip1 (1 time)
|
2004 RhoE inhibits cell cycle progression and Ras-induced transformation.
|
| 47 |
provides a link between the retinoblastoma
(1 time)
|
Cell Biology
(1 time)
|
---
|
2007 E2F-dependent induction of p14ARF during cell cycle re-entry in human T cells.
|
| 48 |
PVs cause neoplastic transformation by inhibiting retinoblastoma
(1 time)
|
Pathology
(1 time)
|
PV (1 time)
SCCs (1 time)
UV-exposed (1 time)
|
2012 Loss of retinoblastoma protein, but not p53, is associated with the presence of papillomaviral DNA in feline viral plaques, Bowenoid in situ carcinomas, and squamous cell carcinomas.
|
| 49 |
RB-associated protein
(1 time)
|
Ophthalmology
(1 time)
|
Rb (1 time)
|
2018 Immunohistochemical assay for neuron-specific enolase, synaptophysin, and RB-associated protein as a diagnostic aid in advanced retinoblastomas.
|
| 50 |
Rb1-encoded protein
(1 time)
|
Molecular Biology
(1 time)
|
---
|
2006 The retinoblastoma tumor-suppressor gene, the exception that proves the rule.
|
| 51 |
readily phosphorylated the retinoblastoma protein
(1 time)
|
Cell Biology
(1 time)
|
CDK4 (1 time)
|
1994 D-type cyclin-dependent kinase activity in mammalian cells.
|
| 52 |
substrate-retinoblastoma protein
(1 time)
|
Cell Biology
(1 time)
|
Cdk's (1 time)
|
1998 [Dependence of the process leading to phosphorylation of retinoblastoma protein (pRb) on the status of the actin cytoskeleton].
|
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