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Abbreviation: ppGpp
Appearance Frequency: 36 time(s)
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Long Form No. Long Form Research Area Co-occurring Abbreviation PubMed/MEDLINE Info. (Year, Title)
phosphorylated guanine nucleotides guanosine-5'-diphosphate-3'-diphosphate
(2 times)
Bacteriology
(1 time)
PNPase (1 time)
1982 Evidence that Bacillus subtilis sporulation induced by the stringent response is caused by the decrease in GTP or GDP.
Physiological concentrations of guanosine 5'-diphosphate 3'-diphosphate
(2 times)
Microbiology
(1 time)
DAP (1 time)
relA (1 time)
1976 Stringent control of peptidoglycan biosynthesis in Escherichia coli K-12.
preparation of guanosine tetraphosphate
(2 times)
Biochemistry
(2 times)
--- 1974 Preparation of guanosine tetraphosphate (ppGpp) and guanosine pentaphosphate (pppGpp) from Escherichia coli ribosomes.
protein, DNA, and guanosine 5'-diphosphate 3'-diphosphate
(2 times)
Biochemistry
(1 time)
cAMP (1 time)
1978 Unusual effects of 5a,6-anhydrotetracycline and other tetracyclines. Inhibition of guanosine 5'-diphosphate 3'-diphosphate metabolism, RNA accumulation and other growth-related processes in Escherichia coli.
P2 directly senses the concentrations of guanosine 5'-disphosphate 3'-diphosphate
(1 time)
Microbiology
(1 time)
iNTP (1 time)
2004 Unique roles of the rrn P2 rRNA promoters in Escherichia coli.
pasteurianum rapidly reduced the intracellular levels of guanosine 5'-diphosphate 3'-diphosphate
(1 time)
Microbiology
(1 time)
--- 1981 Relative levels of guanosine 5'-diphosphate 3'-diphosphate (ppGpp) in some N2 fixing bacteria during derepression and repression of nitrogenase.
penicillin tolerance is directly attributable to guanosine 3',5'-bispyrophosphate
(1 time)
Bacteriology
(1 time)
--- 1995 Direct correlation between overproduction of guanosine 3',5'-bispyrophosphate (ppGpp) and penicillin tolerance in Escherichia coli.
phase is dependent upon the alarmone guanosine 3',5'-bispyrophosphate
(1 time)
Bacteriology
(1 time)
--- 2006 Growth phase-dependent regulation of the extracytoplasmic stress factor, sigmaE, by guanosine 3',5'-bispyrophosphate (ppGpp).
phase, encompasses an accumulation of guanosine 5'-diphosphate 3'-diphosphate
(1 time)
Bacteriology
(1 time)
Sti (1 time)
1990 Responses to multiple-nutrient starvation in marine Vibrio sp. strain CCUG 15956.
10  phenotype with respect to the accumulation of guanosine 3',5'-bispyrophosphate
(1 time)
Bacteriology
(1 time)
--- 1995 Isolation of a carbon starvation regulatory mutant in a marine Vibrio strain.
11  phosphorylated compounds, two of which were identified as guanosine 5'-diphosphate-3'-diphosphate
(1 time)
Biochemistry
(1 time)
--- 1975 RNA synthesis and the accumulation of guanine nucleotides during growth shift down in the blue-green alga Anacystis nidulans.
12  plant chloroplasts, guanosine tetraphosphate
(1 time)
Science
(1 time)
RSH (1 time)
SAS1 (1 time)
2015 Catalytic mechanism and allosteric regulation of an oligomeric (p)ppGpp synthetase by an alarmone.
13  polyamines in the variation of intracellular guanosine 5'-diphosphate 3'-diphosphate
(1 time)
Cell Biology
(1 time)
PSI (1 time)
1994 A role for polyamines in the control of ppGpp levels in Escherichia coli.
14  polymerase-binding protein DksA is a cofactor required for guanosine tetraphosphate
(1 time)
Microbiology
(1 time)
--- 2006 The guanosine tetraphosphate (ppGpp) alarmone, DksA and promoter affinity for RNA polymerase in regulation of sigma-dependent transcription.
15  pool size of guanosine 5'-3'-diphosphate-3'diphosphate
(1 time)
Biochemistry
(1 time)
--- 1975 Synthesis and turnover of basal level guanosine tetraphosphate in Escherichia coli.
16  poor nutrient conditions by production of the alarmone guanosine tetraphosphate
(1 time)
Biotechnology
(1 time)
--- 1995 Evaluation of the E. coli ribosomal rrnB P1 promoter and phage-derived lysis genes for the use in a biological containment system: a concept study.
17  possess common biosynthetic pathways for generating guanosine 3',5'-(bis)pyrophosphate
(1 time)
Botany
(1 time)
GDPNP (1 time)
2012 ppGpp inhibits peptide elongation cycle of chloroplast translation system in vitro.
18  post-transcriptionally, whereas the alarmone guanosine tetraphosphate
(1 time)
Natural Science Disciplines
(1 time)
SPI-2 (1 time)
2018 Guanosine tetraphosphate relieves the negative regulation of Salmonella pathogenicity island-2 gene transcription exerted by the AT-rich ssrA discriminator region.
19  preceded by rapid expansion of the guanosine 5'-diphosphate 3'-diphosphate
(1 time)
Microbiology
(1 time)
nif (1 time)
1984 Nitrogenase synthesis in Klebsiella pneumoniae: enhanced nif expression without accumulation of guanosine 5'-diphosphate 3'-diphosphate.
20  presence of 0.3 to 0.6 mM guanosine-5'-diphosphate-3'-diphosphate
(1 time)
Biochemistry
(1 time)
EF-Tu (1 time)
1979 Studies on stringent control in a cell-free system. Regulation by guanosine-5'-diphosphate-3'-diphosphate of the synthesis of elongation factor Tu.
21  present in vitro transcription system, guanosine tetraphosphate
(1 time)
Cell Biology
(1 time)
--- 1979 Identification of initiation sites for the in vitro transcription of rRNA operons rrnE and rrnA in E. coli.
22  previously shown that aprE expression requires guanosine 3',5'-bisdiphosphate
(1 time)
Biochemistry
(1 time)
LM (1 time)
2003 Inhibition of Bacillus subtilis aprE expression by lincomycin at the posttranscriptional level through inhibition of ppGpp synthesis.
23  production of large amounts of a regulatory nucleotide, guanosine-3',5'-(bis)pyrophospahte
(1 time)
Biochemistry
(1 time)
--- 2002 Multiple mechanisms of transcription inhibition by ppGpp at the lambdap(R) promoter.
24  production of signaling molecules guanosine 5'-diphosphate,3'-diphosphate
(1 time)
Science
(1 time)
--- 2018 Regulation of stringent factor by branched-chain amino acids.
25  progeny accumulate the second messenger guanosine 3',5'-bispyrophosphate
(1 time)
Microbiology
(1 time)
--- 2000 Legionella pneumophila pathogesesis: a fateful journey from amoebae to macrophages.
26  protein biosynthesis inhibitors, which also block the fomration of guanosine-5'-diphosphate-3'-diphosphate
(1 time)
Microbiology
(1 time)
SLT (1 time)
1990 Control of the activity of the soluble lytic transglycosylase by the stringent response in Escherichia coli.
27  protein showed 8-oxo-dGTP, Ap₄A, and guanosine-3',5'-tetraphosphate
(1 time)
Biochemistry
(1 time)
8-oxo-dGTP (1 time)
NUDX (1 time)
2015 Structure and molecular characterization of barley nudix hydrolase genes.
28  purified RNA polymerase holoenzyme is inhibited by guanosine tetraphosphate
(1 time)
Biochemistry
(1 time)
--- 1989 Promoter selectivity of Escherichia coli RNA polymerase: omega factor is responsible for the ppGpp sensitivity.
29  putative guanosine 3',5'-bispyrophosphate
(1 time)
Biochemistry
(1 time)
--- 2002 A RelA-SpoT homolog (Cr-RSH) identified in Chlamydomonas reinhardtii generates stringent factor in vivo and localizes to chloroplasts in vitro.
30  putative guanosine 5'-diphosphate 3'-diphosphate
(1 time)
Microbiology
(1 time)
--- 2005 Roles of Brucella abortus SpoT in morphological differentiation and intramacrophagic replication.
31  pyrophosphate from the 3'-position of guanosine 3',5'-bis(diphosphate)
(1 time)
Genetics
(1 time)
--- 1980 Uncharged tRNA inhibits guanosine 3',5'-bis (diphosphate) 3'-pyrophosphohydrolase [ppGppase], the spoT gene product, from Escherichia coli.
32  sn-glycerol-3-phosphate acyltransferase to guanosine 5-diphosphate-3-diphosphate
(1 time)
Biochemistry
(1 time)
CoA (1 time)
1975 The involvement of guanosine 5-diphosphate-3-diphosphate in the regulation of phospholipid biosynthesis in Escherichia coli. Lack of ppGpp inhibition of acyltransfer from acyl-ACP to sn-glycerol 3-phosphate.