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Abbreviation: scFv
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Long Form No. Long Form Research Area Co-occurring Abbreviation PubMed/MEDLINE Info. (Year, Title)
single-chain variable fragment
(966 times)
Allergy and Immunology
(156 times)
ELISA (57 times)
mAb (51 times)
CAR (34 times)
1994 Real-time biospecific interaction analysis of a natural human polyreactive monoclonal IgM antibody and its Fab and scFv fragments with several antigens.
single-chain Fv
(464 times)
Biochemistry
(93 times)
mAb (34 times)
CEA (16 times)
ELISA (16 times)
1991 Conformational stability, folding, and ligand-binding affinity of single-chain Fv immunoglobulin fragments expressed in Escherichia coli.
single-chain fragment variable
(287 times)
Allergy and Immunology
(52 times)
ELISA (15 times)
mAbs (15 times)
mAb (12 times)
1995 An improved phage display antibody cloning system using newly designed PCR primers optimized for Pfu DNA polymerase.
single-chain Fv fragment
(99 times)
Biochemistry
(27 times)
mAb (6 times)
ELISA (4 times)
IMAC (4 times)
1993 Chaperonin assisted phage display of antibody fragments on filamentous bacteriophages.
single-chain variable fragment antibody
(39 times)
Biochemistry
(4 times)
ELISA (4 times)
icELISA (3 times)
Ad (2 times)
1999 pSKAP/S: An expression vector for the production of single-chain Fv alkaline phosphatase fusion proteins.
single-chain Fv antibody fragment
(37 times)
Allergy and Immunology
(8 times)
ELISA (2 times)
IMAC (2 times)
mAb (2 times)
1994 Intra- and extracellular expression of an scFv antibody fragment in E. coli: effect of bacterial strains and pathway engineering using GroES/L chaperonins.
single-chain variable antibody fragment
(32 times)
Hematology
(5 times)
EGFP (2 times)
FVIII (2 times)
HCV (2 times)
1998 Production, crystallization and diffraction to atomic resolution of an antibody Fv specific for the blood-group A oligosaccharide antigen.
single-chain Fv antibody
(29 times)
Allergy and Immunology
(7 times)
DCs (2 times)
mAb (2 times)
125I-MFE-23-his (1 time)
1997 Seed-specific immunomodulation of abscisic acid activity induces a developmental switch.
single-chain Fv domain
(8 times)
Biophysics
(2 times)
CII (1 time)
ICAbs (1 time)
ITAM (1 time)
1993 Specific activation and targeting of cytotoxic lymphocytes through chimeric single chains consisting of antibody-binding domains and the gamma or zeta subunits of the immunoglobulin and T-cell receptors.
10  single-chain Fv molecule
(5 times)
Molecular Biology
(2 times)
Ab (1 time)
cDNA (1 time)
CEA (1 time)
1996 A melanoma-specific VH antibody cloned from a fusion phage library of a vaccinated melanoma patient.
11  Single chain Fv antibody fragments
(3 times)
Biochemistry
(2 times)
PVYO (1 time)
2000 Virus strain discrimination using recombinant antibodies.
12  single chain constructs combining the variable fragments
(2 times)
Biochemistry
(1 time)
HuscFv (1 time)
sc-dsFv (1 time)
2010 Engineering anti-vascular endothelial growth factor single chain disulfide-stabilized antibody variable fragments (sc-dsFv) with phage-displayed sc-dsFv libraries.
13  single chain Fv fragment of an antibody
(2 times)
Biochemistry
(1 time)
ABA (1 time)
2004 Directed in vitro evolution and crystallographic analysis of a peptide-binding single chain antibody fragment (scFv) with low picomolar affinity.
14  single-chain antibody fragment of variable region
(2 times)
Biochemistry
(1 time)
ciELISA (1 time)
EPO (1 time)
NCS/T (1 time)
2004 Single chain antibodies that recognize the N-glycosylation site.
15  single-chain fixed-variable
(2 times)
Neoplasms
(1 time)
DR5 (2 times)
mAb (1 time)
rAAV (1 time)
2006 Therapeutic expression of an anti-death receptor 5 single-chain fixed-variable region prevents tumor growth in mice.
16  single-chain immunoglobulin Fv fragments
(2 times)
Biochemistry
(2 times)
BsFv (1 time)
1997 Cloning and expression in Escherichia coli of a human gelatinase B-inhibitory single-chain immunoglobulin variable fragment (scFv).
17  Single-chain variable fragment antibodies
(2 times)
Biochemical Phenomena
(1 time)
GPI (1 time)
scFvs (1 time)
2005 Sheep red blood cells armed with anti-CD20 single-chain variable fragments (scFvs) fused to a glycosylphosphatidylinositol (GPI) anchor: a strategy to target CD20-positive tumor cells.
18  single-chain variable fragment from this monoclonal antibody
(2 times)
Chemistry Techniques, Analytical
(1 time)
EHEC (1 time)
EPEC (1 time)
2003 Influence of solution and gas phase processes on protein-carbohydrate binding affinities determined by nanoelectrospray Fourier transform ion cyclotron resonance mass spectrometry.
19  fragment--single chain fragment-variable
(1 time)
Botany
(1 time)
mAb (1 time)
2003 Anti-solasodine glycoside single-chain Fv antibody stimulates biosynthesis of solasodine glycoside in plants.
20  scaffold to form immunoreactive PEG
(1 time)
Biochemistry
(1 time)
scFv-Cys (1 time)
2004 Production of soluble ScFvs with C-terminal-free thiol for site-specific conjugation or stable dimeric ScFvs on demand.
21  scFv fragments
(1 time)
Nanotechnology
(1 time)
HC (1 time)
MNP (1 time)
TZ (1 time)
2013 Assessing the in vivo targeting efficiency of multifunctional nanoconstructs bearing antibody-derived ligands.
22  scFv, designated as Dmab
(1 time)
Biotechnology
(1 time)
hPBMCs (1 time)
scFvs (1 time)
2008 High-level expression of a functional humanized single-chain variable fragment antibody against CD25 in Pichia pastoris.
23  scFv, SS
(1 time)
Biotechnology
(1 time)
--- 1999 Improving antibody affinity by mimicking somatic hypermutation in vitro.
24  selected for detailed cross-reactivity studies, generation of recombinant single-chain antibody
(1 time)
Virology
(1 time)
aa (1 time)
HBV (1 time)
mAbs (1 time)
2016 New broadly reactive neutralizing antibodies against hepatitis B virus surface antigen.
25  sequences, V(H)/V(L) interface engineering could be generally applied to various
(1 time)
Biochemistry
(1 time)
--- 2010 VH/VL interface engineering to promote selective expression and inhibit conformational isomerization of thrombopoietin receptor agonist single-chain diabody.
26  single chain antibody Fv
(1 time)
Cell Biology
(1 time)
CIR (1 time)
mAb (1 time)
2003 Anti-idiotypic antibody facilitates scFv chimeric immune receptor gene transduction and clonal expansion of human lymphocytes for tumor therapy.
27  single chain Fraction variable
(1 time)
Molecular Biology
(1 time)
ELISA (1 time)
MALDI TOF (1 time)
RANK (1 time)
2014 Expression, characterization, and evaluation of a RANK-binding single chain fraction variable: an osteoclast targeting drug delivery strategy.
28  single chain fragments of the variable regions of human immunoglobulins
(1 time)
Biochemistry
(1 time)
HRV2 (1 time)
OVR (1 time)
RAP (1 time)
1996 Preferential recognition of the very low-density lipoprotein receptor ligand binding site by antibodies from phage display libraries.
29  single chain Fv derivative of a monoclonal antibody
(1 time)
Genetics, Medical
(1 time)
CTLs (1 time)
TCR (1 time)
1995 A spacer region between the single chain antibody- and the CD3 zeta-chain domain of chimeric T cell receptor components is required for efficient ligand binding and signaling activity.
30  single chain Fv fragment of anti-hen egg-white lysozyme antibody
(1 time)
Biomedical Engineering
(1 time)
AP (1 time)
MTG (1 time)
2004 Enzymatic labeling of a single chain variable fragment of an antibody with alkaline phosphatase by microbial transglutaminase.
31  Single chain of fragment of variance of IgG
(1 time)
Neurology
(1 time)
ALS (1 time)
mAb (1 time)
2011 [Antibody therapy targeting ALS-linked misfolded protein].
32  single-chain antibody fragments variable
(1 time)
Biology
(1 time)
IL-1RAcP (1 time)
RFS (1 time)
TNBC (1 time)
2018 Synthetic human monoclonal antibody targets hIL1 receptor accessory protein chain with therapeutic potential in triple-negative breast cancer.
33  single-chain fragment containing antibody V domains
(1 time)
Acquired Immunodeficiency Syndrome
(1 time)
--- 2004 Cross-clade HIV-1 neutralization by an antibody fragment from a lupus phage display library.
34  single-chain Fv Ab
(1 time)
Allergy and Immunology
(1 time)
--- 1996 Multivalent antibody fragments with high functional affinity for a tumor-associated carbohydrate antigen.
35  single-chain Fv configuration
(1 time)
Dermatology
(1 time)
--- 1996 Recombinant anti-human melanoma antibodies are versatile molecules.
36  single-chain Fv dimers genes
(1 time)
Gastrointestinal Diseases
(1 time)
SEC (1 time)
VH-VL (1 time)
2010 Construction of non-covalent single-chain Fv dimers for hepatocellular carcinoma and their biological functions.
37  single-chain intracellular Fv
(1 time)
Cell Biology
(1 time)
CD (1 time)
HP1 (1 time)
Pc (1 time)
2002 Loss of heterochromatin protein 1 (HP1) chromodomain function in mammalian cells by intracellular antibodies causes cell death.
38  single-chain V region fragment
(1 time)
Allergy and Immunology
(1 time)
DCs (1 time)
2012 An anti-nucleic acid antibody delivers antigen to the cross-presentation pathway in dendritic cells and potentiates therapeutic antitumor effects.
39  single-chain variable fragments of immunoglobulin
(1 time)
Biotechnology
(1 time)
FCM (1 time)
GFP (1 time)
TfR (1 time)
2012 Generation and functional characterization of the anti-transferrin receptor single-chain antibody-GAL4 (TfRscFv-GAL4) fusion protein.
40  single-chain variable Fv domain
(1 time)
Biotechnology
(1 time)
Phab (1 time)
SPR (1 time)
2012 Production and characterization of a recombinant single-chain antibody (scFv) for tracing the sigma54 factor of Pseudomonas putida.
41  single-chain variable-fragment molecules
(1 time)
Molecular Biology
(1 time)
ACMV (1 time)
ELISA (1 time)
2000 Expression of functional recombinant antibody molecules in insect cell expression systems.
42  SOST-single-chain Fv
(1 time)
Biochemistry
(1 time)
--- 2014 Expression of sclerostin scFv and the effect of sclerostin scFv on healing of osteoporotic femur fracture in rats.
43  subsets of human cells by envelope modification with antibody fragments
(1 time)
Genetics, Medical
(1 time)
Env (1 time)
MLV (1 time)
SNV (1 time)
2001 Targeted gene transfer to lymphocytes using murine leukaemia virus vectors pseudotyped with spleen necrosis virus envelope proteins.
44  successive panning of the non-immune phage miniantibody
(1 time)
Allergy and Immunology
(1 time)
--- 2011 Generation of scFv phages specific to Staphylococcus enterotoxin C1 by panning on related antigens.
45  Y1-scFv single chain antibody
(1 time)
Allergy and Immunology
(1 time)
vWF (1 time)
2006 Molecular characterization of a human monoclonal antibody that interacts with a sulfated tyrosine-containing epitope of the GPIb receptor and inhibits platelet functions.