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■ Search Result - Abbreviation : siRNA

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Abbreviation: siRNA
Appearance Frequency: 10965 time(s)
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Long Form No. Long Form Research Area Co-occurring Abbreviation PubMed/MEDLINE Info. (Year, Title)
small interfering RNA
(10579 times)
Neoplasms
(1764 times)
RNAi (983 times)
ROS (278 times)
VEGF (252 times)
2001 Post-transcriptional gene silencing in plants.
small interfering ribonucleic acid
(122 times)
Neoplasms
(17 times)
mRNA (8 times)
ELISA (5 times)
HIF-1alpha (5 times)
2003 Molecular mechanisms, diagnosis, and rational approaches to management of and therapy for Charcot-Marie-Tooth disease and related peripheral neuropathies.
small inhibitory RNA
(81 times)
Neoplasms
(16 times)
CCT-eta (3 times)
EGFR (3 times)
GR (3 times)
2003 IL-1alpha-induced COX-2 expression in human intestinal myofibroblasts is dependent on a PKCzeta-ROS pathway.
silencing RNA
(45 times)
Neoplasms
(14 times)
ER (2 times)
HGF (2 times)
IL (2 times)
2003 Induction of G0/G1 cell cycle arrest in ovarian carcinoma cells by the anti-inflammatory drug NS-398, but not by COX-2-specific RNA interference.
short interfering RNA duplexes
(33 times)
Molecular Biology
(8 times)
RNAi (6 times)
RSV (3 times)
dsRNA (2 times)
2002 Silencing of Bruton's tyrosine kinase (Btk) using short interfering RNA duplexes (siRNA).
small interfering double-stranded RNA
(14 times)
Neoplasms
(4 times)
RNAi (3 times)
BI-1 (1 time)
BPH (1 time)
2002 Isoform-specific knockdown and expression of adaptor protein ShcA using small interfering RNA.
silencer RNA
(8 times)
Pharmacology
(2 times)
Ang II (1 time)
APP (1 time)
CCK-8 (1 time)
2003 CUGBP2 plays a critical role in apoptosis of breast cancer cells in response to genotoxic injury.
small interfering oligoribonucleotides
(3 times)
Medicine
(1 time)
CHX (1 time)
DED (1 time)
RCCs (1 time)
2005 Reduction of the antiapoptotic protein cFLIP enhances the susceptibility of human renal cancer cells to TRAIL apoptosis.
small interfering RNA-mediated
(3 times)
Molecular Biology
(1 time)
CD2AP (1 time)
ChIP (1 time)
IRF-1 (1 time)
2007 RNA interference of interferon regulatory factor-1 gene expression in THP-1 cell line leads to Toll-like receptor-4 overexpression/activation as well as up-modulation of annexin-II.
10  specific interfering RNA
(3 times)
Neoplasms
(2 times)
CaMK (1 time)
CK (1 time)
HO-1 (1 time)
2005 Calcium/calmodulin-dependent kinase I and calcium/calmodulin-dependent kinase kinase participate in the control of cell cycle progression in MCF-7 human breast cancer cells.
11  double-stranded interfering RNA
(2 times)
Physicochemical Phenomena
(1 time)
RNAi (2 times)
apoB (1 time)
BDNF (1 time)
2007 RNA interference-mediated inhibition of brain-derived neurotrophic factor expression increases cocaine's cytotoxicity in cultured cells.
12  double-stranded ribonucleotide
(2 times)
Biochemistry
(1 time)
shRNA (1 time)
2011 General method for labeling siRNA by click chemistry with fluorine-18 for the purpose of PET imaging.
13  silencing interference RNA
(2 times)
Cell Biology
(1 time)
BAEpC (1 time)
Eph (1 time)
MPM (1 time)
2014 Tobacco smoke induces epithelial barrier dysfunction via receptor EphA2 signaling.
14  Silencing of mRNA expression by RNA interference
(2 times)
Reproductive Medicine
(1 time)
CASP3 (1 time)
COX (1 time)
POU5F1 (1 time)
2006 Gene expression of cox5a, 5b, or 6b1 and their roles in preimplantation mouse embryos.
15  small interfering RNA technique
(2 times)
Neoplasms
(2 times)
AI (1 time)
LASP1 (1 time)
Rb (1 time)
2007 Overexpression of LASP-1 mediates migration and proliferation of human ovarian cancer cells and influences zyxin localisation.
16  small, interfering, hairpin RNA
(2 times)
Neurology
(1 time)
hpRNA (2 times)
CMV (1 time)
IGF-IR (1 time)
2004 Downregulation of uPA, uPAR and MMP-9 using small, interfering, hairpin RNA (siRNA) inhibits glioma cell invasion, angiogenesis and tumor growth.
17  SMS2-silencing RNA
(2 times)
Cell Biology
(1 time)
ALI (1 time)
HPAECs (1 time)
N2a (1 time)
2012 Role of sphingomyelin synthesis in pulmonary endothelial cell cytoskeletal activation and endotoxin-induced lung injury.
18  subjected MCs to RNA interference
(2 times)
Nephrology
(2 times)
IFN (2 times)
MCs (2 times)
MDA5 (2 times)
2016 Interferon-Stimulated Gene 15, a Type I Interferon-Dependent Transcript, Is Involved in a Negative Feedback Loop in Innate Immune Reactions in Human Mesangial Cells.
19  synthetic interfering RNAs
(2 times)
Histocytochemistry
(1 time)
aiRNAs (1 time)
PCa (1 time)
qRT-PCR (1 time)
2011 Silencing USP22 by asymmetric structure of interfering RNA inhibits proliferation and induces cell cycle arrest in bladder cancer cells.
20  Aire-silenced
(1 time)
Allergy and Immunology
(1 time)
AIRE (1 time)
miRNAs (1 time)
mRNA (1 time)
2013 Autoimmune regulator (Aire) controls the expression of microRNAs in medullary thymic epithelial cells.
21  atelocollagen-small interfering RNA
(1 time)
Molecular Biology
(1 time)
--- 2005 Fiber molecular model of atelocollagen-small interfering RNA (siRNA) complex.
22  double-stranded RNA interference
(1 time)
Biochemistry
(1 time)
ILK (1 time)
2003 Conditional knock-out of integrin-linked kinase demonstrates an essential role in protein kinase B/Akt activation.
23  linc-OIP5-small interfering RNA
(1 time)
Molecular Biology
(1 time)
lincRNAs (1 time)
qRT-PCR (1 time)
2017 Knockdown of linc-OIP5 inhibits proliferation and migration of glioma cells through down-regulation of YAP-NOTCH signaling pathway.
24  pCMV-NF-kappaB-small interference RNA
(1 time)
Gastrointestinal Diseases
(1 time)
ADM (1 time)
HCC (1 time)
MDR (1 time)
2016 Reversal of multidrug resistance of hepatocellular carcinoma cells by metformin through inhibiting NF-kappaB gene transcription.
25  pSilencer-PUMA-small interfering RNA
(1 time)
Neoplasms
(1 time)
mRNA (1 time)
2015 Effect of capilliposide for induction apoptosis in human nasopharyngeal cancer CNE-2 cells through up-regulating PUMA expression.
26  salutary effects were absent in MSC
(1 time)
Cardiology
(1 time)
AWT (1 time)
ELISA (1 time)
GFP (1 time)
2010 Gene manipulated peritoneal cell patch repairs infarcted myocardium.
27  screened and found asmall interfering RNA
(1 time)
Nucleic Acids
(1 time)
AS (1 time)
FGFR2 (1 time)
P253R (1 time)
2018 Adeno-Associated Virus-Mediated RNAi against Mutant Alleles Attenuates Abnormal Calvarial Phenotypes in an Apert Syndrome Mouse Model.
28  secretagogue-small interfering RNA
(1 time)
Rheumatology
(1 time)
HSG (1 time)
SS (1 time)
2011 A secretagogue-small interfering RNA conjugate confers resistance to cytotoxicity in a cell model of Sjogren's syndrome.
29  selective RNA targeting
(1 time)
Biochemistry
(1 time)
--- 2015 Dual oxidase 2 generated reactive oxygen species selectively mediate the induction of mucins by epidermal growth factor in enterocytes.
30  several challenges associated with the cargo
(1 time)
Drug Delivery Systems
(1 time)
--- 2012 Delivery and biodistribution of siRNA for cancer therapy: challenges and future prospects.
31  shell and core, facilitating the independent encapsulations of large
(1 time)
Biomedical Engineering
(1 time)
--- 2017 Core-shell hierarchical mesostructured silica nanoparticles for gene/chemo-synergetic stepwise therapy of multidrug-resistant cancer.
32  short dsRNA oligonucleotides
(1 time)
Neoplasms
(1 time)
HIF (1 time)
IAA (1 time)
NDRG1 (1 time)
2012 Inhibition of N-Myc down regulated gene 1 in in vitro cultured human glioblastoma cells.
33  short hairpin RNA
(1 time)
Medicine
(1 time)
Bcl-2 (1 time)
RT-PCR (1 time)
2015 Overexpression of RLIP76 Required for Proliferation in Meningioma Is Associated with Recurrence.
34  short inhibitory RNA duplexes
(1 time)
Cell Biology
(1 time)
NES (1 time)
2002 Deregulated human Cdc14A phosphatase disrupts centrosome separation and chromosome segregation.
35  short interfering 21-23 mer double-stranded RNA
(1 time)
Biochemistry
(1 time)
LTR (1 time)
RNAi (1 time)
2005 Lentiviral-mediated delivery of combined HIV-1 decoy TAR and Vif siRNA as a single RNA molecule that cleaves to inhibit HIV-1 in transduced cells.
36  show that knockdown of N-CoR either transiently
(1 time)
Cell Biology
(1 time)
--- 2007 A critical role for the co-repressor N-CoR in erythroid differentiation and heme synthesis.
37  show, usingsmall interfering RNA
(1 time)
Biological Science Disciplines
(1 time)
ER (1 time)
V-ATPase (1 time)
2018 IP3 Receptors Preferentially Associate with ER-Lysosome Contact Sites and Selectively Deliver Ca2+ to Lysosomes.
38  SHP-2 genes were knocked down by interference RNA
(1 time)
Ophthalmology
(1 time)
HCE (1 time)
HGF (1 time)
PTPs (1 time)
2008 Association of protein tyrosine phosphatases (PTPs)-1B with c-Met receptor and modulation of corneal epithelial wound healing.
39  signaling pathway, RNA interference
(1 time)
Allergy and Immunology
(1 time)
MyD88 (1 time)
NF (1 time)
PGRPs (1 time)
2008 RNAi suppression of zebrafish peptidoglycan recognition protein 6 (zfPGRP6) mediated differentially expressed genes involved in Toll-like receptor signaling pathway and caused increased susceptibility to Flavobacterium columnare.
40  signaling pathways involved, we performed RNA interference
(1 time)
Breast Neoplasms
(1 time)
--- 2008 G-Protein Inwardly Rectifying Potassium Channel 1 (GIRK1) Knockdown Decreases Beta-Adrenergic, MAP Kinase and Akt Signaling in the MDA-MB-453 Breast Cancer Cell Line.
41  significantly attenuated in IR
(1 time)
Biochemistry
(1 time)
FBPase (1 time)
G6Pase (1 time)
HPTC (1 time)
2017 Reduced Insulin Receptor Expression Enhances Proximal Tubule Gluconeogenesis.
42  significantly increased, compared with CCNY knockdown
(1 time)
Medicine
(1 time)
CCNY (1 time)
HCC (1 time)
qRT-PCR (1 time)
2018 Cyclin Y Modulates the Proliferation, Invasion, and Metastasis of Hepatocellular Carcinoma Cells.
43  significantly inhibited by catalase or by inhibiting the expression
(1 time)
Cardiology
(1 time)
DAPT (1 time)
si (1 time)
TACE (1 time)
2011 Cyclic stretch stimulates vascular smooth muscle cell alignment by redox-dependent activation of Notch3.
44  silence of RBPMS using RNA interference
(1 time)
Pharmacology
(1 time)
CRC (1 time)
miR-21-3p (1 time)
2018 Inhibition of microRNA-21-3p suppresses proliferation as well as invasion and induces apoptosis by targeting RNA-binding protein with multiple splicing through Smad4/extra cellular signal-regulated protein kinase signalling pathway in human colorectal cancer HCT116 cells.
45  silencing approach
(1 time)
Gastroenterology
(1 time)
THTR (1 time)
2012 Relative contribution of THTR-1 and THTR-2 in thiamin uptake by pancreatic acinar cells: studies utilizing Slc19a2 and Slc19a3 knockout mouse models.
46  silencing inhibitory RNA
(1 time)
Nephrology
(1 time)
DA (1 time)
l-DOPA (1 time)
LAT2 (1 time)
2004 The dopamine precursor L-dihydroxyphenylalanine is transported by the amino acid transporters rBAT and LAT2 in renal cortex.
47  silencing RhoA expression
(1 time)
Vascular Diseases
(1 time)
M3G (1 time)
M6G (1 time)
MNTX (1 time)
2006 Methylnaltrexone inhibits opiate and VEGF-induced angiogenesis: role of receptor transactivation.
48  Slc52a2-small interfering RNA
(1 time)
Pharmacology
(1 time)
--- 2013 Involvement of riboflavin transporter RFVT2/Slc52a2 in hepatic homeostasis of riboflavin in mice.
49  small inducible RNA
(1 time)
Molecular Biology
(1 time)
Chk1 (1 time)
2006 Dissecting the roles of checkpoint kinase 1/CDC2 and mitogen-activated protein kinase kinase 1/2/extracellular signal-regulated kinase 1/2 in relation to 7-hydroxystaurosporine-induced apoptosis in human multiple myeloma cells.
50  small inhibitor ribonucleic acid
(1 time)
Otolaryngology
(1 time)
CTGF (1 time)
TGF (1 time)
2016 The role of Smad3 in the fibrotic phenotype in human vocal fold fibroblasts.
51  small inhibitory hairpin RNA
(1 time)
Anatomy
(1 time)
DRG (1 time)
NRP-1 (1 time)
2004 Functional knockdown of neuropilin-1 in the developing chick nervous system by siRNA hairpins phenocopies genetic ablation in the mouse.
52  small inhibitory RNA duplex
(1 time)
Medicine
(1 time)
AFAP1L1 (1 time)
Sp (1 time)
2013 The transcription factor Sp3 regulates the expression of a metastasis-related marker of sarcoma, actin filament-associated protein 1-like 1 (AFAP1L1).
53  small inhibitory RNA molecules
(1 time)
Ophthalmology
(1 time)
IE-3 (1 time)
MCMV (1 time)
2014 Decrease of murine cytomegalovirus-induced retinitis by intravenous delivery of immediate early protein-3-specific siRNA.
54  small interfering complementary RNA
(1 time)
Biochemistry
(1 time)
ECFCs (1 time)
mRNA (1 time)
RNAi (1 time)
2008 Inhibition of alpha-globin gene expression by RNAi.
55  small interfering double-stranded RNA molecules
(1 time)
Biochemistry
(1 time)
CS-HOBT (1 time)
MWs (1 time)
2010 Nucleic acid delivery with chitosan hydroxybenzotriazole.
56  small interfering ribonucleic acid duplexes
(1 time)
Dermatology
(1 time)
DPC (1 time)
2012 Effect of HSPC016 gene expression on the aggregative growth of dermal papillae cells.
57  small interfering RNA of MRTF-A
(1 time)
Brain
(1 time)
--- 2011 Myocardin-related transcription factor-A promoting neuronal survival against apoptosis induced by hypoxia/ischemia.
58  small interfering RNA sequences against
(1 time)
Neoplasms
(1 time)
lncRNA (1 time)
PCa (1 time)
PCGEM1 (1 time)
2014 Reciprocal regulation of PCGEM1 and miR-145 promote proliferation of LNCaP prostate cancer cells.
59  small interfering RNA-mediated posttranscriptional knockdown
(1 time)
Genetics, Medical
(1 time)
Q-ON (1 time)
2005 Engineered Streptomyces quorum-sensing components enable inducible siRNA-mediated translation control in mammalian cells and adjustable transcription control in mice.
60  small interfering RNA-negative
(1 time)
Biomedical Engineering
(1 time)
CLSM (1 time)
FTIR (1 time)
GPC (1 time)
2012 A mPEG-PLGA-b-PLL copolymer carrier for adriamycin and siRNA delivery.
61  Small interfering synthetic double-stranded RNA
(1 time)
Biotechnology
(1 time)
hCTLA4Ig (1 time)
PEI (1 time)
2009 Enhanced delivery of siRNA complexes by sonoporation in transgenic rice cell suspension cultures.
62  small ribonuclear acid
(1 time)
Cell Biology
(1 time)
FABP (1 time)
2015 Expression and function of fatty acid-binding protein 4 in epithelial cell of uterine endometrium.
63  small-interfering oligos
(1 time)
Neoplasms
(1 time)
CRY2 (1 time)
2010 Phenotypic effects of the circadian gene Cryptochrome 2 on cancer-related pathways.
64  smokers with and without COPD, along with RelB knock-down
(1 time)
Pulmonary Medicine
(1 time)
CSE (1 time)
2015 Decreased expression of the NF-kappaB family member RelB in lung fibroblasts from Smokers with and without COPD potentiates cigarette smoke-induced COX-2 expression.
65  specific small EGR-1 interfering RNA
(1 time)
Neoplasms
(1 time)
FCM (1 time)
MTT (1 time)
RT-PCR (1 time)
2009 Down-regulation of Egr-1 by siRNA inhibits growth of human prostate carcinoma cell line PC-3.
66  stabilized AgNPs-Qe with a layer of molecules
(1 time)
Biomimetics
(1 time)
AgNPs-Qe (1 time)
N/P (1 time)
Qe (1 time)
2016 Silver nanoparticles-quercetin conjugation to siRNA against drug-resistant Bacillus subtilis for effective gene silencing: in vitro and in vivo.
67  study was to inhibit alphaV-mediated angiogenesis in vitro using RNAs
(1 time)
Hematology
(1 time)
asON (1 time)
HUVEC (1 time)
2005 Use of RNA interference to inhibit integrin subunit alphaV-mediated angiogenesis.
68  subjected the cells to RNA interference
(1 time)
Medicine
(1 time)
BA (1 time)
dsRNA (1 time)
ELISA (1 time)
2017 CCL5 is induced by TLR 3 signaling in HuCCT1 human biliary epithelial cells: possible involvement in the pathogenesis of biliary atresia.
69  such effects, RNA interference
(1 time)
Zoology
(1 time)
LPS (1 time)
NF (1 time)
QT-PCR (1 time)
2009 Zebrafish peptidoglycan recognition protein SC (zfPGRP-SC) mediates multiple intracellular signaling pathways.
70  supported by ER-alpha downregulation
(1 time)
Medicine
(1 time)
DIM (1 time)
2011 Estrogen induced metastatic modulators MMP-2 and MMP-9 are targets of 3,3'-diindolylmethane in thyroid cancer.
71  suppressed by RNA interference
(1 time)
Pathology
(1 time)
HCCs (1 time)
2006 PIN1 expression contributes to hepatic carcinogenesis.
72  survival experiments after molecular
(1 time)
Neoplasms
(1 time)
ATM (1 time)
HRS (1 time)
2007 Transition in survival from low-dose hyper-radiosensitivity to increased radioresistance is independent of activation of ATM Ser1981 activity.
73  synthetic 21-23 nt RNAs
(1 time)
Biochemistry
(1 time)
ES (1 time)
RNAi (1 time)
2002 Small interfering RNA and gene silencing in transgenic mice and rats.
74  synthetic RNA
(1 time)
Molecular Biology
(1 time)
CJD (1 time)
FAD (1 time)
rpAD (1 time)
2017 Strain-Specific Altered Regulatory Response of Rab7a and Tau in Creutzfeldt-Jakob Disease and Alzheimer's Disease.
75  synthetic RNA oligonucleotides
(1 time)
Cell Biology
(1 time)
hESC (1 time)
2010 Efficient, high-throughput transfection of human embryonic stem cells.