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■ Abbreviation / Long Form : 1-NP / 1-nitropyrene

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Total Number of Papers: 190
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Abbreviation:   1-NP  (>> Co-occurring Abbreviation)
Long Form:   1-nitropyrene
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No. Year Title Co-occurring Abbreviation
2023 Role of Human Aldo-Keto Reductases and Nuclear Factor Erythroid 2-Related Factor 2 in the Metabolic Activation of 1-Nitropyrene via Nitroreduction in Human Lung Cells. 1-AP, AKRs, AOX, CDDO-Im, NQO1, Nrf2, XO
2022 1-Nitropyrene exposure induces mitochondria dysfunction and impairs oocyte maturation in mice. MMP, ROS
2022 Effect of Methyl Gallate on 1-Nitropyrene-Induced Keratinocyte Toxicity in a Human and Canine Skin Model. MAPKKs, MAPKs, MG
2022 Health Risk Assessment of Inhalation Exposure to Airborne Particle-Bound Nitrated Polycyclic Aromatic Hydrocarbons in Urban and Suburban Areas of South China. 2-NF, 9-NT, ILCRs, nitro-PAHs
2022 Mitochondrial ROS-mediated ribosome stalling and GCN2 activation are partially involved in 1-nitropyrene-induced steroidogenic inhibition in testes. ROS
2022 Role of Human Aldo-Keto Reductases in the Nitroreduction of 1-Nitropyrene and 1,8-Dinitropyrene. 1,8-ANP, 1,8-DNP, 1-AP, AKRs
2022 The plant streptolysin S (SLS)-associated gene B confers nitroaromatic tolerance and detoxification. Pen, SLS, TNT
2022 Urinary 1-aminopyrene level in Koreans as a biomarker for the amount of exposure to atmospheric 1-nitropyrene. 1-AP, DEPs, HPLC-FD, nitro-PAH
2022 Uterine decidual stromal cell-derived exosomes mediate the indirect effects of 1-nitropyrene on trophoblast biological behaviors. DKK1, EMT, HDSC-EXOs, HDSCs
10  2021 1-Nitropyrene exposure impairs embryo implantation through disrupting endometrial receptivity genes expression and producing excessive ROS. LIF, ROS
11  2021 1-Nitropyrene Induced Reactive Oxygen Species-Mediated Apoptosis in Macrophages through AIF Nuclear Translocation and AMPK/Nrf-2/HO-1 Pathway Activation. AIF, AOE, CAT, GPx, nitro-PAHs, SOD
12  2021 Assessment of occupational exposure to diesel particulate matter through evaluation of 1-nitropyrene and 1-aminopyrene in surface coal miners, India. 1-AP, DPM
13  2021 Calculating source contributions to urban atmospheric polycyclic aromatic hydrocarbons and nitropolycyclic aromatic hydrocarbons using 1-nitropyrene and pyrene: An application to an Asian dust event. PAHs, PYR
14  2021 Genotoxic effects of 1-nitropyrene in macrophages are mediated through a p53-dependent pathway involving cytochrome c release, caspase activation, and PARP-1 cleavage. ---
15  2021 Proinflammatory Responses of 1-Nitropyrene against RAW264.7 Macrophages through Akt Phosphorylation and NF-kappaB Pathways. IL, NF
16  2021 Reactive oxygen species-evoked endoplasmic reticulum stress mediates 1-nitropyrene-induced epithelial-mesenchymal transition and pulmonary fibrosis. ASMA, EMT, ER, NAC, Re, RI, ROS
17  2020 Calculating sources of combustion-derived particulates using 1-nitropyrene and pyrene as markers. PAHs, Pc, PM, PYR, TSP
18  2020 Long-term 1-nitropyrene exposure induces endoplasmic reticulum stress and inhibits steroidogenesis in mice testes. ---
19  2020 Long-Term Trends in Urban Atmospheric Polycyclic Aromatic Hydrocarbons and Nitropolycyclic Aromatic Hydrocarbons: China, Russia, and Korea from 1999 to 2014. 6-NBaP, BaP, NPAHs, PAHs, PYR, TSP
20  2020 Reactive oxygen species-mediated cellular genotoxic stress is involved in 1-nitropyrene-induced trophoblast cycle arrest and fetal growth restriction. IUGR, NAC, PBN, ROS
21  2019 Acute 1-NP exposure induces inflammatory responses through activating various inflammatory signaling pathways in mouse lungs and human A549 cells. MAPK, NF-kappaB, NPAHs
22  2019 Emission Characteristics of Polycyclic Aromatic Hydrocarbons and Nitro-Polycyclic Aromatic Hydrocarbons from Open Burning of Rice Straw in the North of Vietnam. 2-NF, 2-NP, 6-NC, BaP, Flu, IDP, NPAHs, PAHs, PM, RS, TSP
23  2019 Fluorescence Enhancement of Ethanolic Solution of Nitroarenes and Its Analytical Application. 3-NBA
24  2019 Gestational 1-nitropyrene exposure causes gender-specific impairments on postnatal growth and neurobehavioral development in mice. ---
25  2019 Maternal 1-nitropyrene exposure during pregnancy increases susceptibility of allergic asthma in adolescent offspring. OVA, PND
26  2018 Effects of Ambient Atmospheric PM2.5, 1-Nitropyrene and 9-Nitroanthracene on DNA Damage and Oxidative Stress in Hearts of Rats. 9-NA, BW, GST, HO-1, MDA, PAHs, SOD
27  2018 Evaluation of 1-Nitropyrene as a Surrogate Measure for Diesel Exhaust. DE, DPM, EC, MSHA, OC, TC
28  2018 Gestational 1-nitropyrene exposure causes fetal growth restriction through disturbing placental vascularity and proliferation. ---
29  2018 Quantification of DNA and Protein Adducts of 1-Nitropyrene: Significantly Higher Levels of Protein than DNA Adducts in the Internal Organs of 1-Nitropyrene Exposed Rats. ---
30  2017 Airborne nitro-PAHs induce Nrf2/ARE defense system against oxidative stress and promote inflammatory process by activating PI3K/Akt pathway in A549 cells. 3-NF, DNA-PKcs, HO-1, nitro-PAHs, PM, ROS
31  2017 DNA damage and repair, oxidative stress and metabolism biomarker responses in lungs of rats exposed to ambient atmospheric 1-nitropyrene. ---
32  2017 Long term trends in atmospheric concentrations of polycyclic aromatic hydrocarbons and nitropolycyclic aromatic hydrocarbons: A study of Japanese cities from 1997 to 2014. 6-NBaP, BaP, HPLC, NPAHs, PAH, PAHs, PYR, TSP
33  2017 Oxidative stress and genotoxicity biomarker responses in tilapia (Oreochromis niloticus) exposed to environmental concentration of 1-nitropyrene. ---
34  2016 DNA Damage Potential of Engine Emissions Measured In Vitro by Micronucleus Test in Human Bronchial Epithelial Cells. 3-NBA, EOM, MN
35  2016 Nitro-PAH exposures of occupationally-exposed traffic workers and associated urinary 1-nitropyrene metabolite concentrations. DE
36  2016 Photo-induced toxicity and oxidative stress responses in Tigriopus japonicus exposed to nitro-polycyclic aromatic hydrocarbons and artificial light. nitro-PAHs, ROS
37  2016 Toxic Effects of the Major Components of Diesel Exhaust in Human Alveolar Basal Epithelial Cells (A549). 3-NBA, PAH
38  2015 Combination of precolumn nitro-reduction and ultraperformance liquid chromatography with fluorescence detection for the sensitive quantification of 1-nitronaphthalene, 2-nitrofluorene, and 1-nitropyrene in meat products. 1-NN, 2-NF, nitro-PAHs, UPLC-FLD
39  2015 Mechanistic Basis for the Bypass of a Bulky DNA Adduct Catalyzed by a Y-Family DNA Polymerase. ---
40  2015 Negative Ion Laser Desorption/Ionization Time-of-Flight Mass Spectrometric Analysis of Small Molecules Using Graphitic Carbon Nitride Nanosheet Matrix. BPs, MALDI-TOF MS, nitro-PAHs
41  2015 Neighborhood-Scale Spatial Models of Diesel Exhaust Concentration Profile Using 1-Nitropyrene and Other Nitroarenes. NPAHs
42  2015 Urinary metabolites of 1-nitropyrene in US-Mexico border residents who frequently cross the San Ysidro Port of Entry. 8-OHNP, DPM
43  2015 [Combined effects of 1-nitropyrene and 1,2-naphthoquinone on cytotoxicity and DNA damage in A549 cells]. 1,2-NQ, LDH, ROS
44  2014 AhR and Arnt differentially regulate NF-kappaB signaling and chemokine responses in human bronchial epithelial cells. 1-AP, AhR, Arnt, NF
45  2014 Calcium signaling and beta2-adrenergic receptors regulate 1-nitropyrene induced CXCL8 responses in BEAS-2B cells. beta2AR, IL-8, IL-8, nitro-PAHs
46  2014 DNA adduct formation and induction of detoxification mechanisms in Dreissena polymorpha exposed to nitro-PAHs. PAHs
47  2014 Sensitivity of Salmonella YG5161 for detecting PAH-associated mutagenicity in air particulate matter. PM
48  2013 Differential chemokine induction by 1-nitropyrene and 1-aminopyrene in bronchial epithelial cells: importance of the TACE/TGF-alpha/EGFR-pathway. 1-AP, EGFR, TACE, TGF
49  2013 Mechanisms of chemokine responses by polycyclic aromatic hydrocarbons in bronchial epithelial cells: sensitization through toll-like receptor-3 priming. 1-AP
50  2012 Antimutagenic properties of Mangifera indica L. stem bark extract and evaluation of its effects on hepatic CYP1A1. 2-AAF, BP, CP, DMNA, MSBE
51  2012 Electrochemical genotoxicity assay based on a SOS/umu test using hydrodynamic voltammetry in a droplet. 1,8-DNP, 2AA, 4NQO, AF-2, HAs, PQI, RDE
52  2012 Evaluation of urinary metabolites of 1-nitropyrene as biomarkers for exposure to diesel exhaust in taxi drivers of Shenyang, China. DE, PM
53  2012 Kinetic analysis of the bypass of a bulky DNA lesion catalyzed by human Y-family DNA polymerases. AP, hPolkappa
54  2012 Kinetic studies of heterogeneous reactions of polycyclic aromatic hydrocarbon aerosols with NO₃ radicals. BaA, Ch, PAHs, Py, VUV-ATOFMS
55  2011 2,3,7,8-Tetrachlorodibenzo-p-dioxin's suppression of 1-nitropyrene-induced p53 expression is mediated by cytochrome P450 1A1. AhR, BaP, beta-NF, MDM2, PFT-alpha, TCDD
56  2011 Atmospheric formation of hydroxynitropyrenes from a photochemical reaction of particle-associated 1-nitropyrene. DEPs, SRM
57  2011 DNA damage and DNA damage response in human bronchial epithelial BEAS-2B cells following exposure to 2-nitrobenzanthrone and 3-nitrobenzanthrone: role in apoptosis. 2-NBA, 3-NBA, ATM, Chk, nitro-PAHs, PARP
58  2011 Mechanisms involved in lipid accumulation and apoptosis induced by 1-nitropyrene in Hepa1c1c7 cells. AMPK, BP, nitro-PAH, SCD1
59  2010 Organic pollution and genotoxicity of sediments of the Palun marshes (Berre lagoon, France). 1-AP, dw, PAHs
60  2010 Relationship between DNA damage and micronucleus in mouse liver. CP, DEN, PH
61  2009 1-Nitropyrene stabilizes the mRNA of cytochrome P450 1a1, a carcinogen-metabolizing enzyme, via the Akt pathway. AhR, BaP, Cyp1a1, sh
62  2009 Cytokine and chemokine expression patterns in lung epithelial cells exposed to components characteristic of particulate air pollution. IL, LPS, LT, PM, TNF, ufCB
63  2009 Determination of 1-nitropyrene in low volume ambient air samples by high-performance liquid chromatography with fluorescence detection. HPLC
64  2009 Differential effects of nitro-PAHs and amino-PAHs on cytokine and chemokine responses in human bronchial epithelial BEAS-2B cells. 3-NBA, 3-NF, AhR, IL-8, nitro-PAHs
65  2009 Exposures to particulate air pollution and nitro-polycyclic aromatic hydrocarbons among taxi drivers in Shenyang, China. 2-NFL, 2-NP, EC, NPAHs, OC, PM
66  2009 Low levels of the air pollutant 1-nitropyrene induce DNA damage, increased levels of reactive oxygen species and endoplasmic reticulum stress in human endothelial cells. AhR, ER, HUVECs, nitro-PAHs, ROS
67  2009 Signalling pathways involved in 1-nitropyrene (1-NP)-induced and 3-nitrofluoranthene (3-NF)-induced cell death in Hepa1c1c7 cells. 3-NF, AIF, Chk, EndoG, PCDs
68  2008 1-Nitropyrene (1-NP) induces apoptosis and apparently a non-apoptotic programmed cell death (paraptosis) in Hepa1c1c7 cells. PI
69  2008 Aldo-keto reductase 1C2 is essential for 1-nitropyrene's but not for benzo[a]pyrene's induction of p53 phosphorylation and apoptosis. AKRs, phen, UA
70  2008 Hibiscus sabdariffa L. extracts inhibit the mutagenicity in microsuspension assay and the proliferation of HeLa cells. HAE, PCA
71  2008 Sorptive behavior of nitro-PAHs in street runoff and their potential as indicators of diesel vehicle exhaust particles. DEP, GC-MS, NPAHs, PAHs
72  2007 Analysis of 1-nitropyrene in air particulate matter standard reference materials by using two-dimensional high performance liquid chromatography with online reduction and tandem mass spectrometry detection. 1-AP, DPM, PM
73  2007 Identification and quantification of 1-nitropyrene metabolites in human urine as a proposed biomarker for exposure to diesel exhaust. DEP, NPAHs
74  2007 Polycyclic aromatic hydrocarbons aggravate antigen-induced nasal blockage in experimental allergic rhinitis. BaP, PAHs
75  2006 Nitrocompound activation by cell-free extracts of nitroreductase-proficient Salmonella typhimurium strains. 1,3-DNP, 1,6-DNP, 1,8-DNP, 2,7-DNF, 2-NF, 4NQO, CFE, MTZ, NFN, NFZ, NR
76  2005 Binding effect of polychlorinated compounds and environmental carcinogens on rice bran fiber. DFs, GC, HPLC, PCB, PCDDs, PCDFs, RBF
77  2005 Genotoxic damage in mine workers exposed to diesel exhaust, and the effects of glutathione transferase genotypes. BIOMODEM
78  2005 Suppressive effect of 1-nitropyrene on benzo[a]pyrene-induced CYP1A1 protein expression in HepG2 cells. BaP, CYP1A1, PAHs, ROS
79  2004 Effects of exposure to diesel exhaust particles (DEP) on pulmonary metabolic activation of mutagenic agents. 2-AF, 2AA, CB, DEP
80  2004 Vibrational spectra and surface-enhanced vibrational spectra of 1-nitropyrene. DFT, RAIRS, RRS, SEIRA, SERS, SEVS
81  2003 Antimutagenic activity of phenolic compounds, oligosaccharides and quinolizidinic alkaloids from Lupinus campestris seeds. CH, PC, Qas
82  2003 Comparative study of the antioxidant effect of ardisin and epigallocatechin gallate in rat hepatocytes exposed to benomyl and 1-nitropyrene. EGCG, GPx, GR, MDA
83  2003 Exposure to dust and particle-associated 1-nitropyrene of drivers of diesel-powered equipment in underground mining. ---
84  2002 Comparative mutagenesis of the C8-guanine adducts of 1-nitropyrene and 1,6- and 1,8-dinitropyrene in a CpG repeat sequence. A slipped frameshift intermediate model for dinucleotide deletion. 1,6- and 1,8-DNPs
85  2002 DNA adducts from nitroreduction of 2,7-dinitrofluorene, a mammary gland carcinogen, catalyzed by rat liver or mammary gland cytosol. 2,7-diNF, 2-NF
86  2002 Leaf extract from Ardisia compressa protects against 1-nitropyrene-induced cytotoxicity and its antioxidant defense disruption in cultured rat hepatocytes. AC
87  2002 Long-term effects of 1-nitropyrene on oncogene and tumor suppressor gene expression. ---
88  2002 Polycyclic aromatic hydrocarbons induce IL-8 expression through nuclear factor kappaB activation in A549 cell line. IL-8, PAH
89  2002 Salmonella typhimurium mutagenicity tester strains that overexpress oxygen-insensitive nitroreductases nfsA and nfsB. 1,6-DNP, 2-NF, 2-NN, 4NQO, NF
90  2001 Metabolic activation of carcinogenic 1-nitropyrene by human cytochrome P450 1B1 in Salmonella typhimurium strain expressing an O-acetyltransferase in SOS/umu assay. 1-AP, HPLC, OAT
91  2000 Antimutagenicity of ethanol extracts of bee glue against environmental mutagens. 4-NO, ECD, EROD, IQ
92  2000 Bioactivation of diesel exhaust particle extracts and their major nitrated polycyclic aromatic hydrocarbon components, 1-nitropyrene and dinitropyrenes, by human cytochromes P450 1A1, 1A2, and 1B1. 1,8-DNP, 2-NF, 3-NF, DEP
93  2000 Differential incision of bulky carcinogen-DNA adducts by the UvrABC nuclease: comparison of incision rates and the interactions of Uvr subunits with lesions of different structures. ---
94  2000 Influence of DNA repair on mutation spectra in Salmonella. 2-AAF, Ames
95  2000 Polycyclic aromatic hydrocarbon carcinogens increase ubiquitination of p21 protein after the stabilization of p53 and the expression of p21. mRNA, PAHs
96  2000 Recognition and incision of site-specifically modified C8 guanine adducts formed by 2-aminofluorene, N-acetyl-2-aminofluorene and 1-nitropyrene by UvrABC nuclease. AF, AP
97  2000 The effects of 1-nitropyrene, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and 7,12-dimethylbenz[a]anthracene on 8-hydroxy-2'-deoxyguanosine levels in the rat mammary gland and modulation by dietary 1,4-phenylenebis(methylene) selenocyanate. DMBA, PhIP
98  1999 Biological fate of [14C]-1-nitropyrene in rats following intragastric administration. ---
99  1999 Neoplastic potential of rat tracheal epithelial cell lines induced by 1-nitropyrene and dibenzo(a,i)pyrene. CFE, DBP, EGVs, RTE, SCC
100  1999 The DNA repair inhibitors hydroxyurea and cytosine arabinoside enhance the sensitivity of the alkaline single-cell gel electrophoresis ('comet') assay in metabolically-competent MCL-5 cells. 2-NF, 3-MCA, 8-MeIQx, DES, DMBA, HU, MNNG, PhIP