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■ Abbreviation / Long Form : 3alpha-diol / 3alpha-androstanediol

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Total Number of Papers: 23
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Abbreviation:   3alpha-diol  (>> Co-occurring Abbreviation)
Long Form:   3alpha-androstanediol
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No. Year Title Co-occurring Abbreviation
2019 Design and development of letrozole nanoemulsion: A comparative evaluation of brain targeted nanoemulsion with free letrozole against status epilepticus and neurodegeneration in mice. 5 alpha-DHT, KA, LET, LET-NE, LET-NE, PDI, SE
2018 Aromatase inhibition by letrozole attenuates kainic acid-induced seizures but not neurotoxicity in mice. 3alpha-HSOR, 5 alpha-DHT, DHT, KA
2017 Effects of non-contingent cocaine on 3alpha-androstanediol. I. Disruption of male sexual behavior. ---
2013 Neurosteroid 3alpha-androstanediol efficiently counteracts paclitaxel-induced peripheral neuropathy and painful symptoms. ---
2012 Gestational or acute restraint in adulthood reduces levels of 5alpha-reduced testosterone metabolites in the hippocampus and produces behavioral inhibition of adult male rats. DHT
2012 [The antiepileptic role of 3alpha-androstanediol on the epileptic rats induced by pentylenetetrazole]. EEG, PTZ, TP
2009 Antiseizure effects of 3alpha-androstanediol and/or 17beta-estradiol may involve actions at estrogen receptor beta. ERs
2007 Pre-receptor regulation of the androgen receptor. 5 alpha-DHT, AKR, AR, HSDs
2006 Androgens' effects to enhance learning may be mediated in part through actions at estrogen receptor-beta in the hippocampus. AS-ODNs, DHT, ERs
10  2006 Self-administration of 3alpha-androstanediol increases locomotion and analgesia and decreases aggressive behavior of male hamsters. ---
11  2004 5alpha-reduced androgens may have actions in the hippocampus to enhance cognitive performance of male rats. 3alpha-HSD, DHT
12  2004 Dissection of the physiological interconversion of 5alpha-DHT and 3alpha-diol by rat 3alpha-HSD via transient kinetics shows that the chemical step is rate-determining: effect of mutating cofactor and substrate-binding pocket residues on catalysis. 3alpha-HSDs, 5 alpha-DHT
13  2004 Mnemonic effects of testosterone and its 5alpha-reduced metabolites in the conditioned fear and inhibitory avoidance tasks. DHT
14  2004 Testosterone modulation of seizure susceptibility is mediated by neurosteroids 3alpha-androstanediol and 17beta-estradiol. DHT, PTZ
15  2004 Testosterone's analgesic, anxiolytic, and cognitive-enhancing effects may be due in part to actions of its 5alpha-reduced metabolites in the hippocampus. DHT
16  2004 Testosterone's metabolism in the hippocampus may mediate its anti-anxiety effects in male rats. 3alpha-HSD, DHT
17  2003 Human type 3 3alpha-hydroxysteroid dehydrogenase (aldo-keto reductase 1C2) and androgen metabolism in prostate cells. 17beta-HSD, 5 alpha-DHT, AKRs, NADPH
18  2003 Proposed mechanism for sperm chromatin condensation/decondensation in the male rat. 3alpha-HSD, 5 alpha-DHT, ABP
19  2003 Role of human type 3 3alpha-hydroxysteroid dehydrogenase (AKR1C2) in androgen metabolism of prostate cancer cells. 3alpha-HSD, 5 alpha-DHT, AKRs
20  2002 The nucleus accumbens as a site of action for rewarding properties of testosterone and its 5alpha-reduced metabolites. CPP, DHT, NA
21  2001 The testosterone metabolite and neurosteroid 3alpha-androstanediol may mediate the effects of testosterone on conditioned place preference. AR, CPP, DHT, GBR, NA
22  1998 Androgen concentrations and their receptors in the periurethral region are higher than those of the subcapsular zone in benign prostatic hyperplasia (BPH). ARc, ARn, BPH, DHT
23  1975 In vivo androgen retention in mouse kidney. DHT