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■ Abbreviation / Long Form : 5-HETE / 5-hydroxy-6,8,11,14-eicosatetraenoic acid

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Total Number of Papers: 66
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Abbreviation:   5-HETE  (>> Co-occurring Abbreviation)
Long Form:   5-hydroxy-6,8,11,14-eicosatetraenoic acid
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No. Year Title Co-occurring Abbreviation
2017 Structure-activity relationship study of beta-oxidation resistant indole-based 5-oxo-6,8,11,14-eicosatetraenoic acid (5-oxo-ETE) receptor antagonists. 5-LO, 5-oxo-ETE, OXE-R
2014 Two Potent OXE-R Antagonists: Assignment of Stereochemistry. 5-oxo-ETE, AA, HPLC
2011 5-oxo-ETE is a major oxidative stress-induced arachidonate metabolite in B lymphocytes. 5-oxo-ETE, AA, LTB4
2011 Enhanced formation of 5-oxo-6,8,11,14-eicosatetraenoic acid by cancer cells in response to oxidative stress, docosahexaenoic acid and neutrophil-derived 5-hydroxy-6,8,11,14-eicosatetraenoic acid. 5-HEDH, 5-LO, 5-oxo-ETE, NEM
2009 Oxidative stress-induced changes in pyridine nucleotides and chemoattractant 5-lipoxygenase products in aging neutrophils. 5-oxo-ETE
2009 Substrate selectivity of 5-hydroxyeicosanoid dehydrogenase and its inhibition by 5-hydroxy-Delta6-long-chain fatty acids. 5-HEDH, 5-LO, 5-oxo-ETE
2008 Anti-inflammatory and anti-tumour effects of Abies georgei extracts. AA
2008 [Effect of herba schizonepetae volatile oil (STO) on activity of 5-lipoxygenase in rat thoracic cavity leukocytes]. 5-LO, AA, LTB4, STO
2007 Airway epithelial cells synthesize the lipid mediator 5-oxo-ETE in response to oxidative stress. 5-HEDH, 5-oxo-ETE
10  2006 Metabolism of 5-hydroxy-6,8,11,14-eicosatetraenoic acid by human endothelial cells. 5-oxo-ETE
11  2005 Biochemistry, biology and chemistry of the 5-lipoxygenase product 5-oxo-ETE. 5-HEDH
12  2001 Role of nitric oxide in the metabolism of arachidonic acid in the rat anterior pituitary gland. COX, LOX, NO
13  2000 5-Lipoxygenase-derived oxylipins from the red alga Rhodymenia pertusa. 5-HEPE, 5R,6S-diHETE
14  2000 LTA(4)-derived 5-oxo-eicosatetraenoic acid: pH-dependent formation and interaction with the LTB(4) receptor of human polymorphonuclear leukocytes. 5,12-diHETEs, 5,6-diHETEs, 5-oxo-ETE, PMN
15  1997 Correlation between arachidonic acid oxygenation and luminol-induced chemiluminescence in neutrophils: inhibition by diethyldithiocarbamate. 5-LOX, DTC, LTB4, PLA2
16  1996 Stimulating properties of 5-oxo-eicosanoids for human monocytes: synergism with monocyte chemotactic protein-1 and -3. ETE, LTB4, MCP
17  1996 Synthesis of 5-oxo-6,8,11,14-eicosatetraenoic acid by human monocytes and lymphocytes. 5-oxo-ETE, LTB4, PMA
18  1996 The suppression of 5-lipoxygenation of arachidonic acid in human polymorphonuclear leucocytes by the 15-lipoxygenase product (15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoic acid: structure-activity relationship and mechanism of action. LTB4, PMN
19  1995 5-Oxo-6,8,11,14-eicosatetraenoic acid is a potent stimulator of human eosinophil migration. 5-oxo-15-hydroxy-ETE, 5-oxo-ETE, PAF
20  1995 Effects of stilbenes isolated from medicinal plants on arachidonate metabolism and degranulation in human polymorphonuclear leukocytes. 5,12-diHETE, IC50, LTC4, PMNL
21  1995 Formation of a 5-oxo metabolite of 5,8,11,14,17-eicosapentaenoic acid and its effects on human neutrophils and eosinophils. 5-HEPE, 5-oxo-EPE, 5-oxo-ETE, EPA
22  1994 Effects of phorbol myristate acetate on the synthesis of 5-oxo-6,8,11,14-eicosatetraenoic acid by human polymorphonuclear leukocytes. 5-oxo-ETE, LTB4, PMA, PMNL
23  1994 Inhibitory effects of sulfonated shale oils (ammonium bituminosulphonates, Ichthyols) on enzymes of polyenoic fatty acid metabolism. 13-HpODE
24  1994 Role of nitric oxide in eicosanoid synthesis and uterine motility in estrogen-treated rat uteri. NMMA, NP, PGE2, TXB2
25  1993 Stimulation of human neutrophils by 5-oxo-6,8,11,14-eicosatetraenoic acid by a mechanism independent of the leukotriene B4 receptor. 5,15-di-HETE, 5-oxo-15-hydroxy-ETE, 5-oxo-ETE, LTB4
26  1993 [A comparison of the effects of 5-hydroxyeicosatetraenoic acid and hepoxilin A3 on the plasticity of the snail neuronal cholinoreceptors]. ---
27  1992 Enhancement of platelet 12-HETE production in the presence of polymorphonuclear leukocytes during calcium ionophore stimulation. 12-HETE, PMNs
28  1991 Actions of gallic esters on the arachidonic acid metabolism of human polymorphonuclear leukocytes. ---
29  1991 Arachidonic acid metabolites and chloride secretion in rabbit distal colonic mucosa. AA, PGF2 alpha, TXB2
30  1990 Biosynthesis of platelet-activating factor (PAF) in human polymorphonuclear leucocytes. The role of lyso-PAF disposal and free arachidonic acid. 15-HETE, LTB4, MIX, PAF, PMN
31  1990 Transformation of arachidonic acid by 5- and 15-lipoxygenase pathways in bovine adrenal fasciculata cells. 11,14,15-THET, 15-HETE, 15-HPETE
32  1989 Mechanism of release of beta-endorphin from rat pituitary cells. Role of lipoxygenase products of arachidonic acid. beta-End-IR
33  1989 The inhibition of 5-lipoxygenase by RG 6866. 5-LOX, PMN
34  1988 Synergistic stimulation of neutrophils. Possible involvement of 5-hydroxy-6,8,11,14-eicosatetraenoate in superoxide release. ---
35  1987 Arachidonic acid and its lipoxygenase metabolites stimulate prolactin release in superfused pituitary cells. 15-HETE, LT, TRH
36  1987 Formation of leukotriene B4, 20-hydroxy leukotriene B4 and other arachidonic acid metabolites by macrophages during peritonitis in patients with continuous ambulatory peritoneal dialysis. 6-keto-PGF1 alpha, CAPD, LTB4, TXB2
37  1987 Involvement of 5-lipoxygenase pathway in norepinephrine stimulation of rat pineal melatonin synthesis. NDGA, NE
38  1987 Kinetic studies on the inactivation of 5-lipoxygenase by 5(S)-hydroperoxyeicosatetraenoic acid. 5-HPETE, AA, DTT
39  1987 Relationship of glucocorticoid suppression of arachidonic acid metabolism to alteration of neutrophil function. ADCC, LTB4
40  1987 Stimulation of gonadotropin release by arachidonic acid and its lipoxygenase metabolites in superfused pituitary cells. 15-HETE
41  1987 Stimulation of luteinizing hormone release and cyclic nucleotide production by arachidonic acid in cultured pituitary gonadotrophs. cAMP, GnRH, LH
42  1987 Studies on the activities of tannins and related compounds, X. Effects of caffeetannins and related compounds on arachidonate metabolism in human polymorphonuclear leukocytes. LTB4, PGE2, PMNL
43  1986 Metabolism of 5-hydroxyicosatetraenoate by human neutrophils: production of a novel omega-oxidized derivative. 5,20-diHETE
44  1986 Studies on the biosynthesis of leukotrienes in guinea pig lung in vitro by use of high-performance liquid chromatography. LTs, RP-HPLC
45  1985 Characterization and separation of the arachidonic acid 5-lipoxygenase and linoleic acid omega-6 lipoxygenase (arachidonic acid 15-lipoxygenase) of human polymorphonuclear leukocytes. 15-HETE, 15-HPETE, 5-HPETE, RP-HPLC
46  1985 Cyclooxygenase and lipoxygenase pathways in the preimplantation rabbit uterus and blastocyst. ---
47  1985 Double bond requirement for the 5-lipoxygenase pathway. ---
48  1985 Effects of stilbene derivatives on arachidonate metabolism in leukocytes. HHT, IC50
49  1985 Inhibition of platelet and neutrophil phospholipase A2 by hydroxyeicosatetraenoic acids (HETES). A novel pharmacological mechanism for regulating free fatty acid release. 12-HETE, 15-HETE, HETEs, PLA2
50  1985 Lipoxygenase products of arachidonic acid modulate biosynthesis of platelet-activating factor (1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine) by human neutrophils via phospholipase A2. 5-HPETE, NDGA
51  1985 Mechanism of action of gonadotropin releasing hormone: role of lipoxygenase products of arachidonic acid in luteinizing hormone release. ETYA, GnRH, LH, NDGA
52  1985 The 5-lipoxygenase products can modulate the synthesis of platelet-activating factor (alkyl-acetyl GPC) in Ca-ionophore A23187-stimulated rat peritoneal macrophages. 14C-alkyl-acetyl GPC, 14C-alkyl-acyl GPC, 5-HPETE, BPB, IND
53  1984 Activation of a 15-lipoxygenase/leukotriene pathway in human polymorphonuclear leukocytes by the anti-inflammatory agent ibuprofen. PMNs
54  1984 Nonsteroidal anti-inflammatory drugs stimulate 15-lipoxygenase/leukotriene pathway in human polymorphonuclear leukocytes. NSAIDs, PMN
55  1984 The effect of aspirin on the metabolism of exogenous arachidonic acid in human polymorphonuclear leukocytes. 14C-AA, PMNL
56  1983 Biosynthesis of cyclooxygenase and lipoxygenase metabolites of arachidonic acid by rabbit renal microsomes. 12-HETE, AA, LT, RP-HPLC, UV
57  1983 Inhibition of platelet thromboxane synthetase by sulfasalazine. LTB4
58  1983 Modulation of insulin secretion by lipoxygenase products of arachidonic acid. Relation to lipoxygenase activity of pancreatic islets. 12-HETE, 15-HETE, 15-HPETE, BHT, NDGA
59  1982 Evidence for pulmonary release of 5-hydroxyeicosatetraenoic acid (5-hete) during endotoxemia in unanesthetized sheep. ---
60  1982 Sulfasalazine inhibits the synthesis of chemotactic lipids by neutrophils. 5,12 diHETE
61  1981 Effect of various lipoxygenase metabolites of arachidonic acid on degranulation of polymorphonuclear leukocytes. ---
62  1981 Esterification of an endogenously synthesized lipoxygenase product into granulocyte cellular lipids. HHT
63  1981 Evidence for inhibition of leukotriene A4 synthesis by 5,8,11,14-eicosatetraynoic acid in guinea pig polymorphonuclear leukocytes. ETYA
64  1980 Lipoxygenation of arachidonic acid as a source of polymorphonuclear leukocyte chemotactic factors in synovial fluid and tissue in rheumatoid arthritis and spondyloarthritis. NIA, RA, SA
65  1980 Monohydroxyeicosatetraenoic acids (HETEs) induce degranulation of human neutrophils. 12-HETE
66  1979 Metabolism of arachidonic acid in ionophore-stimulated neutrophils. Esterification of a hydroxylated metabolite into phospholipids. ---