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■ Abbreviation / Long Form : ACSL / acyl-CoA synthetase

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Total Number of Papers: 81
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Abbreviation:   ACSL  (>> Co-occurring Abbreviation)
Long Form:   acyl-CoA synthetase
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No. Year Title Co-occurring Abbreviation
2022 ACSL3 regulates lipid droplet biogenesis and ferroptosis sensitivity in clear cell renal cell carcinoma. 5-LOX, ACSL3, ccRCC
2022 Molecular Characterization, Tissue Distribution Profile, and Nutritional Regulation of acsl Gene Family in Golden Pompano (Trachinotus ovatus). ---
2021 Gender dependent differences in lipid metabolism in individuals with type 2 diabetes mellitus. FAS, HOMA-IR, MCAT, NF-kbeta, OADs, PPARgamma, SREBP1, TNF-alpha, VLDL
2021 Palmitate-mediated induction of neuropeptide Y expression occurs through intracellular metabolites and not direct exposure to proinflammatory cytokines. MIF, NAMPT, NPY
2021 Weighted gene co-expression network analysis of the salt-responsive transcriptomes reveals novel hub genes in green halophytic microalgae Dunaliella salina. AccC, ALDO, DEGs, KEGG, LOOCV, MAP3K13, RCD1, WGCNA
2020 Effects and mechanisms of fatty acid metabolism‑mediated glycolysis regulated by betulinic acid‑loaded nanoliposomes in colorectal cancer. BA, CPT, CRC, HK, PK, PKM2
2020 Long-Chain Acyl-CoA Synthetase 4-Mediated Fatty Acid Metabolism Sustains Androgen Receptor Pathway-Independent Prostate Cancer. AR
2020 Long-chain acyl-CoA synthetase-1 mediates the palmitic acid-induced inflammatory response in human aortic endothelial cells. LPS, PA, SFA, TLR
2020 Low Expression of Sirtuin 1 in the Dairy Cows with Mild Fatty Liver Alters Hepatic Lipid Metabolism. ACC, APOE, CAT, CPT1, CPT2, FAS, GSH-Px, L-FABP, LCAD, LDLR, MnSOD, MTTP, p45 NF-E2, PPARalpha, ROS, SIRT1, TG
10  2020 Molecular Cloning, Characterization, and Expression Regulation of Acyl-CoA Synthetase 6 Gene and Promoter in Common Carp Cyprinus carpio. acyl-CoA, PPARalpha, SP1, SREBP-1c, TFs
11  2020 Suppression of long chain acyl-CoA synthetase blocks intracellular fatty acid flux and glucose uptake in skeletal myotubes. DAG, TAG
12  2020 The Echinodermata PPAR: Functional characterization and exploitation by the model lipid homeostasis regulator tributyltin. LBD, PPAR, RXR, TBT
13  2019 Diet and Exercise Training Influence Skeletal Muscle Long-Chain acyl-CoA Synthetases. HFD, LFD, SED
14  2019 It takes a village: channeling fatty acid metabolism and triacylglycerol formation via protein interactomes. GPAT, OMM, TAG
15  2018 Increasing Acyl CoA thioesterase activity alters phospholipid profile without effect on insulin action in skeletal muscle of rats. ACOT, EDL, HFD
16  2018 Lactobacillus gasseri in the Upper Small Intestine Impacts an ACSL3-Dependent Fatty Acid-Sensing Pathway Regulating Whole-Body Glucose Homeostasis. ---
17  2018 Modeling the Transition From Decompensated to Pathological Hypertrophy. ---
18  2018 Regulatory mechanism of fatty acid‑CoA metabolic enzymes under endoplasmic reticulum stress in lung cancer. ACOT, ER, SLC27A4, UPRs
19  2018 Syntaxin 17 promotes lipid droplet formation by regulating the distribution of acyl-CoA synthetase 3. ER, LDs, SNARE, Stx17
20  2018 The effects of ginsenoside Rb1 on fatty acid β-oxidation, mediated by AMPK, in the failing heart. ADR, AMPK, CPT, FAO, Gs-Rbl, HF, MCAD, PCr
21  2017 Complementary ACSL isoforms contribute to a non-Warburg advantageous energetic status characterizing invasive colon cancer cells. CRC, MUFA, PUFA
22  2017 Long-chain acyl-CoA synthetase isoforms differ in preferences for eicosanoid species and long-chain fatty acids. EETs
23  2017 Low acyl-CoA synthetase 5 expression in colorectal carcinomas is prognostic for early tumour recurrence. ACSL5
24  2017 Triacsin C reduces lipid droplet formation and induces mitochondrial biogenesis in primary rat hepatocytes. LD, NAFLD, TAG
25  2016 Astrocyte arachidonate and palmitate uptake and metabolism is differentially modulated by dibutyryl-cAMP treatment. dbcAMP, FABP, SNCA
26  2016 Long-chain acyl-CoA synthetase 2 knockdown leads to decreased fatty acid oxidation in fat body and reduced reproductive capacity in the insect Rhodnius prolixus. ---
27  2016 Systematic Analysis of Gene Expression Alterations and Clinical Outcomes for Long-Chain Acyl-Coenzyme A Synthetase Family in Cancer. ---
28  2015 Cardiac energy dependence on glucose increases metabolites related to glutathione and activates metabolic genes controlled by mechanistic target of rapamycin. FA
29  2015 Eicosapentaenoic Acid Prevents Saturated Fatty Acid-Induced Vascular Endothelial Dysfunction: Involvement of Long-Chain Acyl-CoA Synthetase. HUVEC, PA
30  2015 Long-chain acyl-CoA synthetase in fatty acid metabolism involved in liver and other diseases: an update. ---
31  2014 A peroxisomal long-chain acyl-CoA synthetase from Glycine max involved in lipid degradation. TAG
32  2014 Arachidonic acid downregulates acyl-CoA synthetase 4 expression by promoting its ubiquitination and proteasomal degradation. AA
33  2014 Compartmentalized acyl-CoA metabolism in skeletal muscle regulates systemic glucose homeostasis. FA
34  2014 Deficiency of oncostatin M receptor beta (OSMRbeta) exacerbates high-fat diet-induced obesity and related metabolic disorders in mice. OSM, OSMRbeta, WT
35  2014 High-level exogenous trans10, cis12 conjugated linoleic acid plays an anti-lipogenesis role in bovine mammary epithelial cells. acetyl-CoA, BMECs, CLA, DGAT2, FAS, SCD1, TAG, UFA
36  2014 Inhibition of long chain fatty acyl-CoA synthetase (ACSL) and ischemia reperfusion injury. ---
37  2014 Role of long-chain acyl-CoA synthetase 4 in formation of polyunsaturated lipid species in hepatic stellate cells. HSC, LDs, PUFAs, TAG
38  2013 Diversity and history of the long-chain acyl-CoA synthetase (Acsl) gene family in vertebrates. ACS
39  2013 Effect of non-esterified fatty acids on fatty acid metabolism-related genes in calf hepatocytes cultured in vitro. ACADL, ACC, CPT IA, NEB
40  2013 Eicosapentaenoic acid suppresses palmitate-induced cytokine production by modulating long-chain acyl-CoA synthetase 1 expression in human THP-1 macrophages. EPA, JELIS, LPS, TNF
41  2013 Gestational diabetes mellitus decreases placental uptake of long-chain polyunsaturated fatty acids: involvement of long-chain acyl-CoA synthetase. AA, DHA, GDM, LCPUFAs
42  2013 High-fructose diet downregulates long-chain acyl-CoA synthetase 3 expression in liver of hamsters via impairing LXR/RXR signaling pathway. LXR, LXRE, RXR
43  2013 Identification and biochemical characterization of five long-chain acyl-coenzyme A synthetases from the diatom Phaeodactylum tricornutum. ---
44  2013 Overexpression of human fatty acid transport protein 2/very long chain acyl-CoA synthetase 1 (FATP2/Acsvl1) reveals distinct patterns of trafficking of exogenous fatty acids. PA, PC, PE, PI, PS
45  2013 Palmitic acid induces osteoblastic differentiation in vascular smooth muscle cells through ACSL3 and NF-kappaB, novel targets of eicosapentaenoic acid. ACS, BMP, EPA, FFAs, HASMC, PA, VSMC
46  2013 Propylisopropylacetic acid (PIA), a constitutional isomer of valproic acid, uncompetitively inhibits arachidonic acid acylation by rat acyl-CoA synthetase 4: a potential drug for bipolar disorder. AA, BD, MTMCD, PIA, PID, VPA
47  2012 Evaluation of the porcine ACSL4 gene as a candidate gene for meat quality traits in pigs. ---
48  2012 Novel triacsin C analogs as potential antivirals against rotavirus infections. TG
49  2011 ACSL3 and GSK-3beta are essential for lipid upregulation induced by endoplasmic reticulum stress in liver cells. ER
50  2011 Insulin and insulin signaling play a critical role in fat induction of insulin resistance in mouse. HFD, STZ
51  2011 Mitochondrial carnitine palmitoyltransferase 1a (CPT1a) is part of an outer membrane fatty acid transfer complex. CPT1a, MOM, VDAC
52  2011 Reduction of serum free fatty acids and triglycerides by liver-targeted expression of long chain acyl-CoA synthetase 3. ---
53  2010 Long chain acyl-CoA synthetase-3 is a molecular target for peroxisome proliferator-activated receptor delta in HepG2 hepatoma cells. OSM, PPARdelta, PPRE
54  2010 Valproate uncompetitively inhibits arachidonic acid acylation by rat acyl-CoA synthetase 4: relevance to valproate's efficacy against bipolar disorder. AA, DHA, VPA
55  2009 Hepatic expression of long-chain acyl-CoA synthetase 3 is upregulated in hyperlipidemic hamsters. HFHC
56  2009 Methods to monitor Fatty Acid transport proceeding through vectorial acylation. FATP
57  2009 RNA interference of long-chain acyl-CoA synthetase 6 suppresses the neurite outgrowth of mouse neuroblastoma NB41A3 cells. siRNA
58  2009 Subcellular distribution of key enzymes of lipid metabolism during the euthermia-hibernation-arousal cycle. FAS
59  2009 Suppression of long chain acyl-CoA synthetase 3 decreases hepatic de novo fatty acid synthesis through decreased transcriptional activity. ACSL3, FATP, siRNA
60  2009 Targeting the fatty acid transport proteins (FATP) to understand the mechanisms linking fatty acid transport to metabolism. FATP, FATP
61  2009 The role of alpha-synuclein in brain lipid metabolism: a downstream impact on brain inflammatory response. SNCA
62  2008 Association between fatty acid compositions and genotypes of FABP4 and LXR-alpha in Japanese black cattle. cyt b5, DGAT2, LXRalpha
63  2008 Fatty acid transport and activation and the expression patterns of genes involved in fatty acid trafficking. FATP, qPCR
64  2008 Functional domains of the fatty acid transport proteins: studies using protein chimeras. FATP
65  2008 Mammalian long-chain acyl-CoA synthetases. ACS
66  2008 Vectorial acylation: linking fatty acid transport and activation to metabolic trafficking. FATP
67  2007 Alpha-synuclein gene ablation increases docosahexaenoic acid incorporation and turnover in brain phospholipids. SNCA
68  2007 Long-chain acyl-CoA synthetases and fatty acid channeling. FATP
69  2007 Mechanistic studies of the long chain acyl-CoA synthetase Faa1p from Saccharomyces cerevisiae. ---
70  2007 Ontogeny of mRNA expression and activity of long-chain acyl-CoA synthetase (ACSL) isoforms in Mus musculus heart. FA
71  2007 Rosiglitazone inhibits acyl-CoA synthetase activity and fatty acid partitioning to diacylglycerol and triacylglycerol via a peroxisome proliferator-activated receptor-gamma-independent mechanism in human arterial smooth muscle cells and macrophages. PPAR, SMCs
72  2006 Acyl-CoA synthetase activity links wild-type but not mutant alpha-synuclein to brain arachidonate metabolism. SNCA
73  2006 Alterations in intestinal fatty acid metabolism in inflammatory bowel disease. IBD, LXR
74  2006 Characterization of the porcine acyl-CoA synthetase long-chain 4 gene and its association with growth and meat quality traits. QTL
75  2006 Direct interaction of Saccharomyces cerevisiae Faa1p with the Omi/HtrA protease orthologue Ynm3p alters lipid homeostasis. ---
76  2006 Mutagenesis of rat acyl-CoA synthetase 4 indicates amino acids that contribute to fatty acid binding. ---
77  2006 Overexpression of acyl-CoA synthetase-1 increases lipid deposition in hepatic (HepG2) cells and rodent liver in vivo. LC-CoA, TG
78  2006 Overexpression of rat long chain acyl-coa synthetase 1 alters fatty acid metabolism in rat primary hepatocytes. Ad-Acsl1, FA
79  2005 Characterization of recombinant long-chain rat acyl-CoA synthetase isoforms 3 and 6: identification of a novel variant of isoform 6. ---
80  2005 Rat long chain acyl-CoA synthetase 5 increases fatty acid uptake and partitioning to cellular triacylglycerol in McArdle-RH7777 cells. Ad-ACSL5, TAG
81  2005 Valproic acid selectively inhibits conversion of arachidonic acid to arachidonoyl-CoA by brain microsomal long-chain fatty acyl-CoA synthetases: relevance to bipolar disorder. ---