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■ Abbreviation / Long Form : AGE / aged garlic extract

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Total Number of Papers: 185
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Abbreviation:   AGE  (>> Co-occurring Abbreviation)
Long Form:   aged garlic extract
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No. Year Title Co-occurring Abbreviation
2021 Aged Garlic Extract Reduces IL-6: A Double-Blind Placebo-Controlled Trial in Females with a Low Risk of Cardiovascular Disease. CAC, CT
2021 Attenuation of chronic tension headache frequency and severity with daily L-arginine and aged garlic extract dietary supplementation. ---
2021 Cytoprotective Potential of Aged Garlic Extract (AGE) and Its Active Constituent, S-allyl-l-cysteine, in Presence of Carvedilol during Isoproterenol-Induced Myocardial Disturbance and Metabolic Derangements in Rats. CAR, HTH, ISO, LDH, MI, SAC, SOD, TBARS
2021 Identification and Characterization of Sulfur Heterocyclic Compounds That Contribute to the Acidic Odor of Aged Garlic Extract. GC-O
2021 S-1-propenylcysteine improves TNF-α-induced vascular endothelial barrier dysfunction by suppressing the GEF-H1/RhoA/Rac pathway. GEF-H1, HUVECs, MLC, S1PC, TNF-alpha
2020 3-Allyltrisulfanyl-alanine Formation during the Preparation of Aged Garlic Extract. ATrSA, SAMC
2020 Aged garlic extract and its constituent, S-allyl-L-cysteine, induce the apoptosis of neuroblastoma cancer cells due to mitochondrial membrane depolarization. MDR, MMD, MPT, NB, RLM, SAC, WT
2020 Aged garlic extract reduces left ventricular myocardial mass in patients with diabetes: A prospective randomized controlled double-blind study. CCTA, DM, LVM
2020 Aged garlic extract reduces low attenuation plaque in coronary arteries of patients with diabetes: A randomized, double-blind, placebo-controlled study. CCTA, DC, DM, LAP, NCP, SD, TP
10  2020 Aged garlic extract rescues ethephon-induced kidney damage by modulating oxidative stress, apoptosis, inflammation, and histopathological changes in rats. Nrf2
11  2020 BACH1 mediates the antioxidant properties of aged garlic extract. BACH1, HMOX1, NO, Nrf2, S1PC, SAC
12  2020 Benefits of aged garlic extract on Alzheimer's disease: Possible mechanisms of action. AD
13  2020 Bioactive components from garlic on brain resiliency against neuroinflammation and neurodegeneration. FruArg, IL, LPS, Nrf2, SAC
14  2020 Characterization of key aroma compounds in aged garlic extract. ---
15  2020 Chemistry of aged garlic: Diversity of constituents in aged garlic extract and their production mechanisms via the combination of chemical and enzymatic reactions. cis-S1PC, GGSAC, GGT, GSAMC, LC, MS, NMR, SAMC
16  2020 Cytoprotective and antioxidant effects of aged garlic extract against adriamycin-induced cardiotoxicity in adult male rats. ADR
17  2020 Effect of S-Allyl -L-Cysteine on MCF-7 Cell Line 3-Mercaptopyruvate Sulfurtransferase/Sulfane Sulfur System, Viability and Apoptosis. CBS, FC, MPST, SAC
18  2020 Effects of aged garlic extract on arterial elasticity in a placebo-controlled clinical trial using EndoPAT™ technology. AI
19  2020 Effects of garlic supplementation on serum inflammatory markers: A systematic review and meta-analysis of randomized controlled trials. CRP, IL-6, RCTs, TNF-alpha
20  2020 Mechanisms underlying the attenuation of chronic inflammatory diseases by aged garlic extract: Involvement of the activation of AMP-activated protein kinase. AMPK
21  2020 Periodontal disease and its prevention, by traditional and new avenues. ---
22  2020 S -1-Propenylcysteine, a sulfur compound in aged garlic extract, alleviates cold-induced reduction in peripheral blood flow in rat via activation of the AMPK/eNOS/NO pathway. AMPK, eNOS, NOx, S1PC, SAC, SAMC
23  2020 Short-term impact of aged garlic extract on endothelial function in diabetes: A randomized, double-blind, placebo-controlled trial. CAVI
24  2020 Sulfur-containing amino acids in aged garlic extract inhibit inflammation in human gingival epithelial cells by suppressing intercellular adhesion molecule-1 expression and IL-6 secretion. hbetaD3, ICAM-1, IL-6, NF-kappaB, S1PC, SAC, SAMC, TNF-alpha
25  2020 The effect of aged garlic extract on the atherosclerotic process - a randomized double-blind placebo-controlled trial. CAC, CVD
26  2020 The preventive and therapeutic application of garlic and other plant ingredients in the treatment of periodontal diseases. ---
27  2019 Aged garlic extract ameliorates fatty liver and insulin resistance and improves the gut microbiota profile in a mouse model of insulin resistance. TG
28  2019 Aged garlic extract and S-allylcysteine increase the GLUT3 and GCLC expression levels in cerebral ischemia. GCLC, i.p, MCAO, qPCR, ROS, SAC
29  2019 Aged garlic extract preserves cutaneous microcirculation in patients with increased risk for cardiovascular diseases: A double-blinded placebo-controlled study. ANOVA
30  2019 Anti-cancer activities of S-allylmercaptocysteine from aged garlic. SAMC
31  2019 Protective effect of aged garlic extracts against hepatotoxicity induced by ethephon in Wistar albino rat. ALT, AST, CAT, Hb, Hct, MDA, RBCs, SOD
32  2018 Aged garlic extract supplementation modifies inflammation and immunity of adults with obesity: A randomized, double-blind, placebo-controlled clinical trial. PBMC
33  2018 Changes of S-Allylmercaptocysteine and gamma-Glutamyl- S-allylmercaptocysteine Contents and Their Putative Production Mechanisms in Garlic Extract during the Aging Process. GGT, GS1PC, GSAC, GSAMC, SAMC
34  2018 In vivo combined treatment of rats with ivermectin and aged garlic extract attenuates ivermectin-induced cytogenotoxicity in bone marrow cells. BW, IVM, MDT
35  2018 Isolation and Identification of Three gamma-Glutamyl Tripeptides and Their Putative Production Mechanism in Aged Garlic Extract. GGS1PC, GGSAC, GGT, LC-MS
36  2018 Safety and efficacy of aged garlic extract in dogs: upregulation of the nuclear factor erythroid 2-related factor 2 (Nrf2) signaling pathway and Nrf2-regulated phase II antioxidant enzymes. Nrf2
37  2018 The antioxidant, aged garlic extract, exerts cytotoxic effects on wild-type and multidrug-resistant human cancer cells by altering mitochondrial permeability. MDR, MPT
38  2018 The Efficacy of Aged Garlic Extract on Gingivitis - A Randomized Clinical Trial. ---
39  2018 The potential effect of garlic extract and curcumin nanoparticles against complication accompanied with experimentally induced diabetes in rats. AGEPs, AST, LDH, MnSOD, OS, qRT-PCR, RAGE, STZ
40  2017 Aged garlic extract exerts endothelium-dependent vasorelaxant effect on rat aorta by increasing nitric oxide production. NE, NO, NOS
41  2017 Aged garlic extract suppresses inflammation in apolipoprotein E-knockout mice. apoE-KO, CRP, IRAK4, p-AMPK, TNF-alpha, TXB2
42  2017 Aged garlic extract suppresses the increase of plasma glycated albumin level and enhances the AMP-activated protein kinase in adipose tissue in TSOD mice. AMPK, TSOD
43  2017 Chemical and Biological Properties of S-1-Propenyl-l-Cysteine in Aged Garlic Extract. S1PC
44  2017 Effects of Aged Garlic Extract on Cholinergic, Glutamatergic and GABAergic Systems with Regard to Cognitive Impairment in Abeta-Induced Rats. AD, GAD
45  2017 Metabolomic study on the antihypertensive effect of S-1-propenylcysteine in spontaneously hypertensive rats using liquid chromatography coupled with quadrupole-Orbitrap mass spectrometry. S1PC, SAC, SBP, SHR, WKY
46  2017 Neuroprotective Effects of Aged Garlic Extract on Cognitive Dysfunction and Neuroinflammation Induced by beta-Amyloid in Rats. AD, IL-1beta, NOR, TNF-alpha
47  2017 Randomized trial evaluating the effect of aged garlic extract with supplements versus placebo on adipose tissue surrogates for coronary atherosclerosis progression. CAC, CI, EAT, PAAT, PAT, SAT
48  2017 The impact of aged garlic extract on adriamycin-induced testicular changes in adult male Wistar rats. ADR
49  2016 Aged garlic extract and S-allylcysteine prevent apoptotic cell death in a chemical hypoxia model. ROS, SAC
50  2016 Aged Garlic Extract Attenuates Neuronal Injury in a Rat Model of Spinal Cord Ischemia/Reperfusion Injury. BBB, I/R
51  2016 Aged Garlic Extract Inhibits Human Platelet Aggregation by Altering Intracellular Signaling and Platelet Shape Change. AC, cGMP, IBMX, sGC
52  2016 Aged Garlic Extract Modifies Human Immunity. NK
53  2016 Aged Garlic Extract Reduces Low Attenuation Plaque in Coronary Arteries of Patients with Metabolic Syndrome in a Prospective Randomized Double-Blind Study. CCTA, DC, LAP, MetS, NCP, TPV
54  2016 Aged garlic extract suppresses platelet aggregation by changing the functional property of platelets. ---
55  2016 Aged Garlic Extract Suppresses the Development of Atherosclerosis in Apolipoprotein E-Knockout Mice. APOE, TC, TGs
56  2016 Alliin Attenuated RANKL-Induced Osteoclastogenesis by Scavenging Reactive Oxygen Species through Inhibiting Nox1. HSCs, Nox1, RANKL, ROS
57  2016 Anti-diabetic and anti-oxidant potential of aged garlic extract (AGE) in streptozotocin-induced diabetic rats. AGE-D, CD, CN, STZ
58  2016 Development of a Method and Validation for the Quantitation of FruArg in Mice Plasma and Brain Tissue Using UPLC-MS/MS. FruArg
59  2016 Development of an Analytic Method for Sulfur Compounds in Aged Garlic Extract with the Use of a Postcolumn High Performance Liquid Chromatography Method with Sulfur-Specific Detection. cis-S1PC, LC-MS, SAMC
60  2016 Effect of the Aged Garlic Extract on Cardiovascular Function in Metabolic Syndrome Rats. CF, MS
61  2016 Effects of aged garlic extract and FruArg on gene expression and signaling pathways in lipopolysaccharide-activated microglial cells. FruArg, LPS
62  2016 Garlic and Heart Disease. CAC, CRP, PWV
63  2016 Gastroprotective effect of garlic in indomethacin induced gastric ulcer in rats. NO
64  2016 Impact of titanium dioxide on androgen receptors, seminal vesicles and thyroid hormones of male rats: possible protective trial with aged garlic extract. AR
65  2016 New insight on using aged garlic extract against toxic impacts of titanium dioxide bulk salt triggers inflammatory and fibrotic cascades in male rats. ---
66  2016 Protective Effects of AGE and Its Components on Neuroinflammation and Neurodegeneration. ---
67  2016 The effects of garlic extract upon endothelial function, vascular inflammation, oxidative stress and insulin resistance in adults with type 2 diabetes at high cardiovascular risk. A pilot double blind randomized placebo controlled trial. RI
68  2015 Aged garlic extract ameliorates the oxidative stress, histomorphological, and ultrastructural changes of cisplatin-induced nephrotoxicity in adult male rats. CP
69  2015 Aged garlic extract enhances heme oxygenase-1 and glutamate-cysteine ligase modifier subunit expression via the nuclear factor erythroid 2-related factor 2-antioxidant response element signaling pathway in human endothelial cells. GCLM, HO-1, Nrf2
70  2015 Aged garlic extract inhibits 1,2-dimethylhydrazine-induced colon tumor development by suppressing cell proliferation. ACF, DMH
71  2015 Antioxidant and hypolipidemic potential of aged garlic extract and its constituent, s-allyl cysteine, in rats. SAC
72  2015 Isolation, purification and identification of antioxidants in an aqueous aged garlic extract. ---
73  2014 Aged garlic extract protects against oxidative stress and renal changes in cisplatin-treated adult male rats. CAT, CP, MDA, SOD
74  2014 Allium sativum: facts and myths regarding human health. ---
75  2014 Effect of aged garlic extract and s-allyl cysteine and their interaction with atenolol during isoproterenol induced myocardial toxicity in rats. CK-MB, ECG, HTH, LDH, SAC, SOD, TBARS
76  2014 Effect of aged garlic extract on immune responses to experimental fibrosarcoma tumor in BALB/c mice. IFN-gamma
77  2014 Effects of aged garlic extract and endurance exercise on skeletal muscle FNDC-5 and circulating irisin in high-fat-diet rat models. FNDC-5, HFD
78  2014 Protective effect of aged garlic extract against the oxidative stress induced by cisplatin on blood cells parameters and hepatic antioxidant enzymes in rats. AST, CAT, CP, MDA, SOD
79  2014 Proteomic analysis of the effects of aged garlic extract and its FruArg component on lipopolysaccharide-induced neuroinflammatory response in microglial cells. FruArg, LPS, NO
80  2014 The protective effect of aged garlic extract on nonsteroidal anti-inflammatory drug-induced gastric inflammations in male albino rats. CAT, MDA, MPO, SOD, TNF-alpha
81  2013 Aged garlic extract enhances exercise-mediated improvement of metabolic parameters in high fat diet-induced obese rats. HFD
82  2013 Aged garlic extract improves adiponectin levels in subjects with metabolic syndrome: a double-blind, placebo-controlled, randomized, crossover study. CV, MS
83  2013 Antioxidant action and therapeutic efficacy of Allium sativum L. ---
84  2013 Comparison of antioxidant activity of hydroethanolic fresh and aged garlic extracts and their effects on cerebral ischemia. GCE
85  2013 Effects of aged garlic extract on left ventricular diastolic function and fibrosis in a rat hypertension model. DS, LV, SBP
86  2013 Effects of the aged garlic extract on spinal cord injury model in rat. MDA, SCI, SOD
87  2013 Evaluation of The Number of CD4(+) CD25(+) FoxP3(+) Treg Cells in Normal Mice Exposed to AFB1 and Treated with Aged Garlic Extract. AFB1, DTH, i.p
88  2013 Immunomodulatory activity of aged garlic extract against implanted fibrosarcoma tumor in mice. IFN-gamma, IL-4, PBS
89  2013 In vitro activity-guided identification of antioxidants in aged garlic extract. HPS
90  2013 Renoprotective effect of aged garlic extract in streptozotocin-induced diabetic rats. ---
91  2013 Synergistic effect of aged garlic extract and naltrexone on improving immune responses to experimentally induced fibrosarcoma tumor in BALB/c mice. IFN-gamma, IL-4, NTX
92  2012 Aged garlic extract and coenzyme Q10 have favorable effect on inflammatory markers and coronary atherosclerosis progression: A randomized clinical trial. CAC, CoQ10, CRP
93  2012 Aged garlic extract inhibits platelet activation by increasing intracellular cAMP and reducing the interaction of GPIIb/IIIa receptor with fibrinogen. FACS
94  2012 Aged garlic extract restores nitric oxide bioavailability in cultured human endothelial cells even under conditions of homocysteine elevation. HAT/MET, Hcy, NO
95  2012 Beneficial effects of aged garlic extract and coenzyme Q10 on vascular elasticity and endothelial function: the FAITH randomized clinical trial. CoQ10, DTM, PWV
96  2012 Independent beneficial effects of aged garlic extract intake with regular exercise on cardiovascular risk in postmenopausal women. AGEI, BMI, CVD, MDA, TC, TG
97  2012 The antioxidant mechanisms underlying the aged garlic extract- and S-allylcysteine-induced protection. SAC
98  2011 Aged garlic extract attenuates cerebral damage and cyclooxygenase-2 induction after ischemia and reperfusion in rats. 8-OHdG, COX-2
99  2011 Aged garlic extract inhibits homocysteine-induced scavenger receptor CD36 expression and oxidized low-density lipoprotein cholesterol uptake in human macrophages in vitro. Hcy, oxLDL
100  2011 Aged garlic extract scavenges superoxide radicals. ---